Dr Matt Sharman
Senior Lecturer in Health Sciences
|Contact Campus||Inveresk Campus|
|Telephone||+61 3 6324 3994|
|Fax||+61 3 6324 3658|
Dr Sharman completed his PhD in 2005 in the area of cholesterol and lipoprotein metabolism, nutritional interventions and cardiovascular disease at the University of Connecticut, USA. His Doctoral work involved two major areas. Firstly, examining the effects of a high-fat, low carbohydrate diet vs. a low-fat diet on weight loss, cardiovascular disease biomarkers and inflammatory cytokines in overweight men and women. Following on from this work, the second component of his PhD involved studying the guinea pig as a potential experimental model of evaluating vascular inflammation in dietary-induced atherosclerosis.
Following his PhD, Dr Sharman completed a Postdoctoral Fellowship (2005-2010) in the field of Alzheimer's disease. During this time his research primarily focused on role of cholesterol, apoE and nutritional compounds in Alzheimer's disease pathology and prevention.
After completing a postdoctoral fellowship, Dr Sharman was employed as a Lecturer in Nutrition and Dietetics (2011-2012) at Edith Cowan University. Where he was responsible for teaching Nutritional Biochemistry, Nutrients and Metabolism and Advanced Concepts in Nutrition to nutrition and dietetics students.
Dr Sharman began at the University of Tasmania as a Senior Lecturer in Health Sciences in July 2012. He is responsible for teaching Nutrition, Biochemistry and Physiology to Biomedical, Exercise and Health Science students. Dr Sharman also stays involved in research looking at the prevention of Alzheimer's disease.
Dr Sharman is currently teaching Introductory Biochemistry (CXA215), Anatomy and Physiology 1 (CXA171), Metabolic Biochemistry (CXA261) and Nutrition and Disease (CXA385).
Dr Sharman's current research interests are directed towards the effect that lifestyle factors, such as nutrition and exercise play in the prevention of chronic diseases, specifically Alzheimer's disease. The development of effective preventative lifestyle therapies could help prevent, or delay many of the chronic diseases seen in our society today. This could result in a substantial decrease in the impact of disease burden to many people, whilst also improving their quality of life. He has established a number of collaborations including Prof Ralph Martins (Edith Cowan University), Assoc Prof Giuseppe Verdile (Curtin University of Technology) and Professor Nicola Lautenschlager (University of Melbourne).
Some of his current research research projects include:
The role of a presenilin 2 truncation (PS2V) in Alzheimer's Disease. Funded by National Health & Medical Research Council, and
A Randomised clinical trial of physical activity to delay the progression of cerebrovascular pathology. Funded by National Health & Medical Research Council.
Research Expertise and Specific Skills
- Cholesterol and Lipid Metabolism in Alzheimer's disease
- Nutritional prevention of Alzheimer's disease
- Polyphenols (Curcumin, EGCG, Resveratrol)
- Omega-3 Essential Fatty Acids (DHA)
- Exercise Interventions in Alzheimer's disease
- Lipoproteins and Cardiovascular disease
- Exercise Interventions in Preventing and Management and Metabolic Syndrome
- Nutritional Interventions in Preventing and Management of Metabolic Syndrome
- Biological Based Complementary and Alternative Medicines in Treatment of Chronic diseases