Lecturer
| Contact Campus | Newnham Campus |
| Building | Building C |
| Room Reference | C214 |
| Telephone | + 61 3 6324 5465 |
| Fax | + 61 3 6324 3658 |
| Anthony.Cook@utas.edu.au |
I teach cell and molecular biology to all undergraduate levels across the School of Human Life Sciences. I am the unit coordinator for Cell and Molecular Biochemistry (CXA262) and teach as part of a larger multi-disciplinary team into Cell Biology and Function (CXA171), Introductory Biochemistry (CXA125) and Human Molecular Biology (CXA300).
NRF2 activation restores disease related metabolic deficiencies in olfactory neurosphere-derived cells from patients with sporadic Parkinson's disease. Cook AL, Vitale AM, Ravishankar S, Matigian N, Sutherland GT, Shan J, Sutharsan R, Perry C, Silburn PA, Mellick GD, Whitelaw ML, Wells CA, Mackay-Sim A, Wood SA. PLoS One. 2011;6(7):e21907.
Disease-specific, neurosphere-derived cells as models for brain disorders. Matigian N, Abrahamsen G, Sutharsan R, Cook AL, Vitale AM, Nouwens A, Bellette B, An J, Anderson M, Beckhouse AG, Bennebroek M, Cecil R, Chalk AM, Cochrane J, Fan Y, Féron F, McCurdy R, McGrath JJ, Murrell W, Perry C, Raju J, Ravishankar S, Silburn PA, Sutherland GT, Mahler S, Mellick GD, Wood SA, Sue CM, Wells CA, Mackay-Sim A. Dis Model Mech. 2010 Nov-Dec;3(11-12):785-98.
POU domain transcription factors: BRN2 as a regulator of melanocytic growth and tumourigenesis. Cook AL, Sturm RA. Pigment Cell Melanoma Res. 2008 Dec;21(6):611-26.
Analysis of cultured human melanocytes based on polymorphisms within the SLC45A2/MATP, SLC24A5/NCKX5, and OCA2/P loci. Cook AL, Chen W, Thurber AE, Smit DJ, Smith AG, Bladen TG, Brown DL, Duffy DL, Pastorino L, Bianchi-Scarra G, Leonard JH, Stow JL, Sturm RA. J Invest Dermatol. 2009 Feb;129(2):392-405.
Human melanoblasts in culture: expression of BRN2 and synergistic regulation by fibroblast growth factor-2, stem cell factor, and endothelin-3. Cook AL, Donatien PD, Smith AG, Murphy M, Jones MK, Herlyn M, Bennett DC, Leonard JH, Sturm RA. J Invest Dermatol. 2003 Nov;121(5):1150-9.
I obtained my PhD in 2004 from the University of Queensland, and have worked as a post-doctoral Research Fellow at the Institute for Molecular Bioscience, University of Queensland (2004-2007), the National Centre for Adult Stem Cell Research, Griffith University (2008-2009) and the School of Human Life Sciences, University of Tasmania (2010-2011). In October 2011, I was appointed to a tenure-track Lecturer position within the School of Human Life Sciences. I am an Investigator on past and current grants from NHMRC, Brain Foundation, Cancer Council Tasmania, Cancer Council Queensland and the University of Tasmania.
Throughout my research career, I have actively sought opportunities focused on using primary human cells to model human diseases and phenotypic traits in vitro. Within this, I have pursued my interests in transcription factor biology and have gained extensive experience in studying different transcription factor families using molecular and cellular techniques in primary cells of different lineages. My current research projects use human cells grown in the laboratory to study the biology of glaucoma and Parkinson’s disease. I have active collaborations within the School of Human Life Sciences (Dr Raj Eri, Assoc Prof Liza Snow, Dr Dean Pountney) and nationally with Dr Alex Hewitt (Centre for Eye Research Melbourne) and Dr Stephen Wood, Assoc Prof George Mellick, and Prof Alan Mackay-Sim (National Centre for Adult Stem Cell Research).