Postgraduate
"BMedLabSc, MasterMedLabSc"
| Contact Campus | Newnham Campus |
| Building | Building C |
| Room Reference | N203 |
| Telephone | +61 3 6324 5400 |
| somari@postoffice.utas.edu.au. |
Transient Receptor Vanilloid 1 (TRPV1) in Haematological Malignancies
Bachelor degree in Medical Laboratory Sciences (JUST, Jordan)
Master degree in Medical Laboratory Sciences/ Haematology and Blood Banking (JUST, Jordan).
Dr Adams, Murray John
AProf Geraghty, Dominic P
Research Supervisor: AProf Khalafallah, Alhossain
Vanilloids are natural substances found in most spicy food and capsaicin is one such vanilloid present in 'hot chilli pepper'. Transient receptor potential vanilloids 1 (TRPV1) is the receptor for capsaicin and was described originally as an afferent neuron nociceptor. Capsaicin has been found to have an anticancer properties; it promotes apoptosis and inhibits cell proliferation in cancer cells. We are investigating the effect of capsaicin on haematological malignant cells and the expression and role of TRPV1 in capsaicin-induced cell activity.
Effect of capsaicin on metabolic activity of the haematological malignant cell lines, THP-1, U266 and U937 cells.