Senior Lecturer
Graduate Research Coordinator
BSc(Hons), PhD(Adelaide)
Contact Details
| Contact Campus | Hobart CBD Campuses |
| Building | Medical Science 2 |
| Room Reference | 240-01 (Level 2) |
| Telephone | +61 3 6226 4681 |
| Fax | +61 3 6226 4682 |
| Bruce.Lyons@utas.edu.au |
General Responsibilities
Dr Lyons' primary responsibility is the teaching of Immunology and Biosciences into units delivered to Nursing, Paramedic, Medicine and Science undergraduate students.
Teaching Responsibilities
Units Taught
- CAM101 - Foundations of Medicine 1
- CAM201 - Fundamentals of Clinical Science 1
- CAM304 - Fundamentals of Clinical Science 3
- CAM305 - Functional Clinical Practice
- CJA212 - Basic Pathological Processes and Immunity
- CJA214 - Microbiology B (Pharmacy)
- CJA313 - Medical Microbiology and Immuniology
- CJA314 - Medical Microbiology and Immuniology
- CXA107 - Fundamentals of Bioscience
- CXA204 - Bioscience 1
- CXA205 - Bioscience 2
- KLA210 - Microbiology
Publications
- Fraser, C. K., Blake, S. J., Diener, K. R., Lyons, A. B., Brown, M. P., Hughes, T. P., & Hayball, J. D. (2009). Dasatinib inhibits recombinant viral antigen-specific murine CD4+ and CD8+ T-cell responses and NK-cell cytolytic activity in vitro and in vivo. Experimental Hematology, 37, 256-265.
- Blake, S. J., Lyons, A. B., & Hughes, T. P. Nilotinib inhibits the Src-family kinase LCK and T-cell function in vitro. Journal of Cellular and Molecular Medicine, 13(3), 599-601.
- Blake, S., Hughes, T. P., Mayrhofer, G. & Lyons, A. B. (2008). The anti-leukaemic Src/Abl kinase inhibitor dasatinib (BMS-354825) inhibits the function of normal human T-lymphocytes in vitro. Clinical Immunology, 127, 330-339.
- Blake, S., Lyons, A. B., Fraser, C., Hayball, J. D. & Hughes, T. P. (2008). Dasatinib suppresses in vitro natural killer cell cytotoxicity. Blood, 111, 4415-4416.
- Diener, K. R., Moldenhauer, L., Lyons, A. B., Brown, M. P., & Hayball, J. D. (2008). Human Flt-3 ligand-mobilized dendritic cells require additional activation to drive effective immune responses. Experimental Hematology, 36, 51-60.
Web Access Research Portal (WARP)
Additional Information
Dr Lyons' PhD research examined the differentiation of human myeloid cells, and since that time he has performed research on immunology and leukaemia and has developed specialised flow cytometric techniques to examine immune phenomena. His career has been predominantly as a researcher at Universities (Edinburgh, UTAS) and research institutes (IMVS, JCSMR, Hanson Institute), and he has maintained a strong involvement in both undergraduate and postgraduate teaching. Before re-joining the University of Tasmania, Dr Lyons was employed in the private sector in the field of vaccine development (Vaxine, Flinders University)
Off-Campus Address
Advocate House
Liverpool Street
Hobart TAS 7000
Research Interests
- Off-target effects on the Immune system of small molecule leukaemia therapies
- Immune regulation and cellular trafficking
- Immune response of the Tasmanian Devil