Lecturer (Microbiology)
Contact Details
| Contact Campus | Hobart CBD Campuses |
| Building | Medical Science 2 |
| Room Reference | 240-02 (Level 2) |
| Telephone | +61 3 6226 4669 |
| Mark.Ambrose@utas.edu.au |
Teaching Responsibilities
Units Taught
- CAM101 - Foundations of Medicine 1
- CAM102 - Foundations of Medicine 2
- CAM201 - Fundamentals of Clinical Practice 1
- CAM202 - Fundamentals of Clinical Practice 2
- KLA210 - Microbiology
- CJA214 - Microbiology B (Pharmacy)
- CJA313 - Medical Microbiology and Immunology
Publications
- Ambrose, M and Gatti RA (2013) Pathogenesis of Ataxia-Telangiectasia: the next generation of ATM functions. Blood (Epub Ahead of Print:doi: 10.1182/blood-2012-09-456897)
- Gizdavic-Nikolaidis, M.R., Bennett, J.R., Swift, S., Easteal, A.J. and Ambrose, M (2011) Broad-spectrum antimicrobial activity of functionalized polyanilines. Acta Biomater., 7, 4204-4209.
- MacPhee D.G, and Ambrose, M (2010) Catabolite-repression of RecA-dependent and RecA-independent spontaneous mutagenesis in stationary phase Escherichia coli. Mutation Research 686, 84-89
- Rusyn, I., Fry, R.C., Begley, T.J., Klapacz, J., Svensson, J.P., Ambrose, M and Samson L.D. (2007) Transcriptional networks in S. cerevisiae linked to an accumulation of base excision repair intermediates. PloS One, 2, e1252.
- Ambrose, M., Goldstine, J.V. and Gatti, R.A. (2007) Intrinsic mitochondrial dysfunction in ATM-deficient lymphoblastoid cells. Human Molecular Genetics, 16, 2154-2164.
Web Access Research Portal (WARP)
Additional Information
Research Interests
The research interests of the laboratory are broad and include studying DNA-damage signalling, DNA repair, and mutagenesis in bacteria, yeast and human model systems. In particular, we emphasise the use of conventional mutation detection assays, along with whole genome and proteome interrogation methodologies, to investigate the impact of physiological stress on the activation and modulation of damage-inducible error-prone DNA repair pathways.