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Lou Roddam

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Louise Roddam

Senior Lecturer in Biochemistry & Molecular Biology

Room 240-03, Medical Science 2, Hobart CBD Campuses

+61 3 6226 4889 (phone)

lfroddam@utas.edu.au

Dr Louise Roddam is currently employed by the University of Tasmania and is an Honorary Associate of the Menzies Institute for Medical Research. She is co-leader of the Host-Pathogen Interactions Group and chair of the Tasmanian branch of the Australian Society for Microbiology. Dr Roddam teaches biochemistry, genetics, molecular biology, and protein chemistry. Prior to 2005 she trained as an NHMRC post-doctoral scientist in the University of Queensland Molecular Microbiology laboratory.

Career summary

Biography

Dr Lousie Roddam trained in two leading laboratories in microbial pathogenesis, one at the Australian National University, the second at the University of Queensland and has a strong research history focused on using molecular techniques to examine host-pathogen interactions.

Research Themes

Dr Roddam's research is aligned with the University's research theme of Better Health. Her work focusses on molecular aspects of bacterial virulence, with a strong interest in developing novel therapies targeting chronic infections in the lungs of people with cystic fibrosis (CF).

Memberships

Professional practice

  • Member of the National Scientific Advisory Council for the Australian Society for Microbiology (ASM) (2010-2012)
  • Scientific Division 4 co-chair (Molecular Microbiology) for the 2011 ASM national conference (2010 - 2012)

Committee associations

  • Scientific Advisor on Tasmanian Human Research Ethics Committee (2013 - current)
  • Chair of Tasmanian Branch of ASM (2007- current)
  • Member of the UTas Institutional Biosafety Committee (IBC) (2008 - current)

Administrative expertise

Panel member:

  • NHMRC (2012- current)
  • Channel 7 Children's Research Foundation (2012)

Conference Organisation:

  • Co-conference covenor, Australian Society for Microbiology (ASM) Bistate conference (Hobart 2009, 2012) 
  • Member of Local Organising Committee (LOC) of ASM National meeting (Hobart, 2011)
  • Member of 13th International Conference on Pseudomonas LOC (Sydney, 2011)

Teaching

Molecular Biology, Cellular Biology, Microbiology, Biochemistry, Immunology, Cystic Fibrosis

Teaching expertise

Dr Roddam currently teaches in a range of subjects offered through the School of Medicine. As a teacher Dr Roddam enjoys witnessing student progression as they learn, integrate and synthesise knowledge. A particular interest of Dr Roddam's is the integration of research skills into undergraduate courses.

Teaching responsibility

Unit Coordinator:

Units Contributed to:

Invitations

Dr Roddam has been invited to give the following conference symposium presentations:

  • 'What can we learn from in vivo transcript analysis of clinical CF samples?' at the National Meeting of the Australian Society for Microbiology, Brisbane 2012
  • 'Microbiology and immune modulation during intravenous antibiotic therapy' at the National Meeting of the Australian Society for Microbiology, Brisbane 2012

View more on Dr Louise Roddam in WARP

Current projects

Dr Roddam's current research focusses on bacterial-host interactions and the development of an anti-pseudomonal therapy with the aim of preventing/treating chronic lung infections for people with cystic fibrosis (CF), infections that are associated with significant morbidity and mortality.

Awards

  • Royal Hobart Hospital Research Foundation Fellowship (2006)
  • Unit-based Teaching Merit Certificate (Immunology and Medical Microbiology) (2005)
  • Australian National University Scholarship (1994)

Expertise

Dr Roddam's expertise lies in:

  • Host-pathogen interactions
  • Bacterial biofilms
  • Lung infections in cystic fibrosis
  • Pseudomonas aeruginosa
  • Molecular biology and gene expression analysis
  • Microbiology
  • Tissue culture
  • Protein purification and proteomics

Research Fields

  • Medical Bacteriology (110801)
  • Respiratory Diseases (110203)
  • Clinical Microbiology (110303)
  • Infectious Diseases (110309)
  • Medical Biochemistry and Metabolomics (110199)
  • Innate Immunity (110707)
  • Infectious Agents (060502)
  • Microbial Genetics (060503)
  • Structural Biology (incl. Macromolecular Modelling) (060112)
  • Neurology and Neuromuscular Diseases (110904)
  • Immunology (110799)
  • Medical Genetics (excl. Cancer Genetics) (110311)
  • Cellular Nervous System (110902)
  • Mycology (060505)
  • Preventive Medicine (111716)
  • Cardiovascular Medicine and Haematology (110299)
  • Bacteriology (060501)
  • Cellular Immunology (110704)
  • Central Nervous System (110903)
  • Pharmaceutical Sciences (111504)
  • Dermatology (110304)
  • Medical Microbiology (110899)
  • Microbial Ecology (060504)
  • Enzymes (060107)
  • Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies) (110702)
  • Otorhinolaryngology (110315)

Research Impact

  • Infectious Diseases (920109)
  • Respiratory System and Diseases (incl. Asthma) (920115)
  • Human Pharmaceutical Treatments (e.g. Antibiotics) (860803)
  • Expanding Knowledge in the Medical and Health Sciences (970111)
  • Endocrine Organs and Diseases (excl. Diabetes) (920106)
  • Inherited Diseases (incl. Gene Therapy) (920110)
  • Nervous System and Disorders (920111)
  • Expanding Knowledge in the Biological Sciences (970106)
  • Expanding Knowledge in the Environmental Sciences (970105)
  • Health (929999)
  • Expanding Knowledge in the Agricultural and Veterinary Sciences (970107)
  • Skin and Related Disorders (920117)
  • Immune System and Allergy (920108)
  • Human Pharmaceutical Products (860899)
  • Diabetes (920104)
  • Surgical Methods and Procedures (920118)
  • Neurodegenerative Disorders Related to Ageing (920112)

Publications

Dr Roddam reviews papers for several international journals (Journal of Molecular Microbiology and Biotechnology, Journal of Cystic Fibrosis, Microbiology).

Total publications

29

Journal Article

(20 outputs)
YearCitationAltmetrics
2015Ee R, Ambrose M, Lazenby C, Williams P, Chan G-K, et al., 'Genome sequences of two Pandoraea pnomenusa isolates recovered 11 months apart from a cystic fibrosis patient', Genome Announcements, 3, (1) Article e01389-14. ISSN 2169-8287 (2015) [Refereed Article]

DOI: 10.1128/genomeA.01389-14 [eCite] [Details]

Co-authors: Ambrose M

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2015Mulcahy EM, Hudson JB, Beggs S, Reid DW, Roddam LF, et al., 'High peripheral blood Th17 percent associated with poor lung function in cystic fibrosis', PLoS One, 10, (3) Article e0120912. ISSN 1932-6203 (2015) [Refereed Article]

DOI: 10.1371/journal.pone.0120912 [eCite] [Details]

Co-authors: Mulcahy EM; Beggs S; Reid DW; Cooley MA

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2013Konings AF, Martin LW, Sharples MJ, Roddam LF, Latham R, et al., 'Pseudomonas aeruginosa uses multiple pathways to acquire iron during chronic infection in cystic fibrosis lungs', Infection and Immunity, 81, (8) pp. 2697-2704. ISSN 0019-9567 (2013) [Refereed Article]

DOI: 10.1128/IAI.00418-13 [eCite] [Details]

Citations: Scopus - 12Web of Science - 13

Co-authors: Latham R; Reid DW

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2013Reid DW, Latham R, Lamont IL, Camara M, Roddam LF, 'Molecular analysis of changes in Pseudomonas aeruginosa load during treatment of a pulmonary exacerbation in cystic fibrosis', Journal of Cystic Fibrosis, 12, (6) pp. 688-699. ISSN 1569-1993 (2013) [Refereed Article]

DOI: 10.1016/j.jcf.2013.03.008 [eCite] [Details]

Citations: Scopus - 6Web of Science - 7

Co-authors: Reid DW; Latham R

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2012Griffin PE, Roddam LF, Belessis YC, Strachan R, Beggs S, et al., 'Expression of PPARγ and Paraoxonase 2 correlated with Pseudomonas aeruginosa infection in Cystic Fibrosis', PLoS One, 7, (7) Article e42241. ISSN 1932-6203 (2012) [Refereed Article]

DOI: 10.1371/journal.pone.0042241 [eCite] [Details]

Citations: Scopus - 6Web of Science - 6

Co-authors: Griffin PE; Beggs S; Cooley MA

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2012Wood-Baker R, Tristram S, Latham R, Haug G, Reid D, et al., 'Molecular detection of Haemophilus influenzae in COPD sputum is superior to conventional culturing methods', British Journal of Biomedical Science, 69, (1) pp. 37-39. ISSN 0967-4845 (2012) [Refereed Article]

[eCite] [Details]

Citations: Scopus - 3Web of Science - 3

Co-authors: Wood-Baker R; Tristram S; Latham R; Reid D

2011Bradbury RS, Tristram SG, Roddam LF, Reid DW, Inglis TJJ, et al., 'Antimicrobial susceptibility testing of cystic fibrosis and non-cystic fibrosis clinical isolates of Pseudomonas aeruginosa: a comparison of three methods', British Journal of Biomedical Science, 68, (1) pp. 1-4. ISSN 0967-4845 (2011) [Refereed Article]

[eCite] [Details]

Citations: Scopus - 1Web of Science - 1

Co-authors: Bradbury RS; Tristram SG; Reid DW; Champion AC

2011Jennings MP, Jen FE, Roddam LF, Apicella MA, Edwards JL, 'Neisseria gonorrhoeae pilin glycan contributes to CR3 activation during challenge of primary cervical epithelial cells', Cellular Microbiology, 13, (6) pp. 885-896. ISSN 1462-5814 (2011) [Refereed Article]

DOI: 10.1111/j.1462-5822.2011.01586.x [eCite] [Details]

Citations: Scopus - 21Web of Science - 18

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2010Anderson R, Roddam LF, Bettiol SS, Sanderson Kevin, Reid DW, 'Biosignificance of bacterial cyanogenesis in the CF lung', Journal of Cystic Fibrosis, 9, (3) pp. 158-164. ISSN 1569-1993 (2010) [Refereed Article]

DOI: 10.1016/j.jcf.2009.12.003 [eCite] [Details]

Citations: Scopus - 11Web of Science - 12

Co-authors: Anderson R; Bettiol SS; Sanderson Kevin; Reid DW

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2010Bradbury RS, Roddam LF, Merritt A, Reid DW, Champion AC, 'Virulence gene distribution in clinical, nosocomial and environmental isolates of Pseudomonas aeruginosa', Journal of Medical Microbiology, 59, (8) pp. 881-890. ISSN 0022-2615 (2010) [Refereed Article]

DOI: 10.1099/jmm.0.018283-0 [eCite] [Details]

Citations: Scopus - 16Web of Science - 14

Co-authors: Bradbury RS; Reid DW; Champion AC

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2009O'May C, Sanderson K, Roddam LF, Kirov SM, Reid DW, 'Iron-binding compounds impair Pseudomonas aeruginosa biofilm formation, especially under anaerobic conditions', Journal of Medical Microbiology, 58, (6) pp. 765-773. ISSN 0022-2615 (2009) [Refereed Article]

DOI: 10.1099/jmm.0.004416-0 [eCite] [Details]

Citations: Scopus - 35Web of Science - 30

Co-authors: O'May C; Sanderson K; Kirov SM; Reid DW

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2009Reid DW, O'May C, Kirov SM, Roddam LF, Lamont IL, et al., 'Iron chelation directed against biofilms as an adjunct to conventional antibiotics', American Journal of Physiology: Lung Cellular and Molecular Physiology, 296, (5) pp. 857-858. ISSN 1040-0605 (2009) [Letter or Note in Journal]

[eCite] [Details]

Co-authors: Reid DW; O'May C; Kirov SM; Sanderson Kevin

2009Reid DW, O'May C, Roddam LF, Lamont IL, 'Chelated iron as an anti-Pseudomonas aeruginosa biofilm therapeutic strategy', Journal of Applied Microbiology, 106, (3) pp. 1058. ISSN 1364-5072 (2009) [Letter or Note in Journal]

[eCite] [Details]

Co-authors: Reid DW; O'May C

2005Paton AW, Jennings MP, Morona R, Wang H, Forareta A, et al., 'Recombinant probiotics for treatment and prevention of enterotoxigenic Escherichia coli diarrhea ', Gastroenterology, 128, (5) pp. 1219-1228. ISSN 0016-5085 (2005) [Refereed Article]

DOI: 10.1053/j.gastro.2005.01.050 [eCite] [Details]

Citations: Scopus - 50Web of Science - 43

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2004Warren MJ, Roddam LF, Power PM, Terry TD, Jennings MP, 'Analysis of the role of pglI in pilin glycosylation of Neisseria meningitidis', FEMS Immunology and Medical Microbiology, 41, (1) pp. 43-50. ISSN 0928-8244 (2004) [Refereed Article]

DOI: 10.1016/j.femsim.2004.01.002 [eCite] [Details]

Citations: Web of Science - 20

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2003Dieckelmann M, Roddam LF, Jennings MP, 'Purification of post-translationally modified proteins from bacteria:: Homologous expression and purification of histidine-tagged pilin from neisseria meningitidis', Protein Expression and Purification, 30, (1) pp. 69-77. ISSN 1046-5928 (2003) [Refereed Article]

DOI: 10.1016/S1046-5928(03)00061-5 [eCite] [Details]

Citations: Web of Science - 3

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2003Power PM, Roddam LF, Rutter K, Fitzpatrick SZ, Srikhanta YN, et al., 'Genetic characterization of pilin glycosylation and phase variation in Neisseria meningitidis', Molecular Microbiology, 49, (3) pp. 833-847. ISSN 0950-382X (2003) [Refereed Article]

DOI: 10.1046/j.1365-2958.2003.03602.x [eCite] [Details]

Citations: Web of Science - 76

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2002Roddam LF, Lewis-Henderson W, Djordjevic M, 'Two novel chromosomal loci influence cultivar-specific nodulation failure in the interaction between strain ANU794 and subterranean clover cv. Woogenellup', Functional Plant Biology: An International Journal of Plant Function, 29 pp. 473-483. ISSN 1445-4408 (2002) [Refereed Article]

[eCite] [Details]

2000Power PM, Roddam LF, Dieckelmann M, Srikhanta YN, Tan YC, et al., 'Genetic characterization of pilin glycosylation in Neisseria meningitidis', Microbiology, 146, (4) pp. 967-979. ISSN 0026-2617 (2000) [Refereed Article]

[eCite] [Details]

1997Roddam LF, Rath A, 'Isolation and characterisation of Metarhizium anisopliae and Beauveria bassiana from subantarctic Macquarie Island', Journal of Invertebrate Pathology: Devoted to The Pathology and Microbiology of Insects and Other Invertebrates, 69 pp. 285-288. ISSN 0022-2011 (1997) [Refereed Article]

[eCite] [Details]

Conference Publication

(9 outputs)
YearCitationAltmetrics
2011Ali N, Cooley MA, Griffin P, Roddam LF, 'Cross kingdom signaling during P. aeruginosa infection of the CF lung results in a decreased capacity of the host to clear the infection', Proceedings of the National Meeting of the Australian Society of Microbiology, Hobart, pp. 127. (2011) [Conference Extract]

[eCite] [Details]

Co-authors: Ali N; Cooley MA; Griffin P

2011Alqurni F, Reid DW, Cooley MA, Roddam LF, 'The immune response of cystic fibrosis patients to different P. aeruginosa strains', Proceedings of the National Meeting of the Australian Society of Microbiology, Hobart, pp. 72. (2011) [Conference Extract]

[eCite] [Details]

Co-authors: Reid DW; Cooley MA

2011Latham R, Roddam LF, Reid DW, 'Monitoring Pseudomonas aeruginosa concentration and virulence gene expression in cystic fibrosis sputum during treatment for exacerbations', Proceedings of the National Meeting of the Australian Society of Microbiology, Hobart, pp. 133. (2011) [Conference Extract]

[eCite] [Details]

Co-authors: Latham R; Reid DW

2011Roddam LF, Latham R, Reid DW, 'Microbiology and immune modulation during intravenous antibiotic therapy for pulmonary exacerbations of CF', National Meeting of the Australian Society of Microbiology, Hobart, pp. 54. (2011) [Conference Extract]

[eCite] [Details]

Co-authors: Latham R; Reid DW

2010Roddam LF, Latham R, Reid DW, 'Gene expression analysis of bacterial populations in patient sputum samples during intravenous antibiotic therapy', National Meeting of the Australian Society of Microbiology, Sydney, pp. 70. (2010) [Conference Extract]

[eCite] [Details]

Co-authors: Latham R; Reid DW

2009Roddam LF, Latham R, Reid DW, 'Gene expression analysis demonstrates that intravenous antibiotic treatment of a chronic lung infection results in reduced bacterial load but increased virulence of surviving bacteria', National Meeting of the Australian Society of Microbiology, Perth, pp. 94-95. (2009) [Conference Extract]

[eCite] [Details]

Co-authors: Latham R; Reid DW

2008Bradbury RS, Champion AC, Roddam LF, Merritt A, Reid DW, et al., 'A survey of virulence genes in Pseudomonas aeruginosa', Australian Society for Microbiology National Scientific Meeting, Melbourne (2008) [Conference Extract]

[eCite] [Details]

Co-authors: Bradbury RS; Champion AC; Reid DW

2008Roddam LF, Latham R, Reid DW, 'Role of Pseudomonas in pulmonary exacerbations of CF', Proceedings of the ANZCF Nurses Conference, August, Hobart (2008) [Conference Extract]

[eCite] [Details]

Co-authors: Latham R; Reid DW

2006Bradbury RS, Champion AC, Roddam LF, Sanderson Kevin, Reid DW, 'Prevalence of exoY and exoS genes in clinical and environmental isolates of Pseudomonas aeruginosa', Australian Society for Microbiology National Scientific Meeting, Gold Coast, pp. P10.14. (2006) [Conference Extract]

[eCite] [Details]

Co-authors: Bradbury RS; Champion AC; Sanderson Kevin; Reid DW

Grants & Funding

Dr Roddam has been the recipient of highly competitive research and equipment funding.

Funding Summary

Number of grants

15

Total funding

$869,743

Projects

Prevalence and virulence of an emerging bacterial pathogen of Tasmanian cystic fibrosis patients (2015)$11,100
Description
Pandoraea, an emerging bacterial pathogen of cystic fibrosis is difficult to identify, is of unknown clinical significance and was recently isolated from a Tasmanian CF patient. we will investigate the prevalence of Pandoraea in Tasmanian CF patients, describe its virulence potential and investigate its susceptilility to our new antimicrobial therapy.
Funding
Royal Hobart Hospital Research Foundation ($11,100)
Scheme
Grant-Clinical Research
Administered By
University of Tasmania
Research Team
Roddam LF; Ambrose M; Beggs S; Cooley MA; Malley RC; Warren Sanchia; Wilson RR; McEwan B
Year
2015
Demonstration of the efficacy of a new therapy against lung infections in a mouse model (2014)$14,500
Funding
University of Tasmania ($14,500)
Scheme
Grant-Research Enhancement (REGS)
Administered By
University of Tasmania
Research Team
Roddam LF
Year
2014
A human paraoxonase 2-based therapy for cystic fibrosis A (2014 - 2016)$15,000
Description
Cystic Fibrosis (CF) is the most common genetic condition affecting Australians. People with CF carry a mutation in a gene, which is essential for maintaining the proper balance of salt and water in lungs. As a result, CF patients experience a continuous build-up of thick and sticky mucous in their lungs, which can be colonised by many different types of microorganisms, and especially by Pseudomonas aeruginosa. Infections by P. aeruginosa cannot be completely eradicated using currently available antibiotics because cells of this organism can group together to live in so-called biofilms (which are essentially protected cell communities), which antibiotics simply fail to penetrate successfully. This project will investigate ways to make P. aeruginosa more susceptible to existing antibiotics. The approach aims to prevent/disrupt the grouping together of individual bacterial cells in the first instance, thereby allowing the antibiotics to kill them more effectively. Current research is producing in the laboratory a human anti-biofilm enzyme, known as human paraoxonase 2 (PON2). PON2 is usually produced inside of human cells, which means it is not able to attack the bacterial cells that usually live outside human cells. By administering the recombinant human PON2 (as an aerosol, for example), together with certain antibiotics, it is anticipated that prevention and/or eradication of P. aeruginosa infections will be possible in people with CF.
Funding
Australian Cystic Fibrosis Research Trust ($15,000)
Scheme
Scholarship-Top-Up
Administered By
University of Tasmania
Research Team
Roddam LF; Cooley MA; Ambrose M
Period
2014 - 2016
Testing a new therapy against lung infections for people with cystic fibrosis (2013)$67,782
Description
P. aeruginosa uses small diffusible signal molecules called acyl-homoserine lactones (AHLs) to alter its growth, which enables it to hide from antibiotic therapies and the immune system of the host thereby preventing its eradication from the lungs. These bacterial AHL molecules can also enter and affect human cells leading to further lung damage. This project aims to demonstrate that a novel therapy that inactivates bacterial AHLs can protect human cells from these molecules. Demonstration of this is the first step in showing that this therapy can protect the lungs of people with CF from P. aeruginosa infections. In summary, this new treatment approach should at a minimum prevent a significant amount of the lung damage that occurs, resulting in better quality of life and increased life span. More importantly, this therapy also has the potential to prevent P. aeruginosa lung infections in CF.
Funding
Clifford Craig Medical Research Trust ($67,782)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Roddam LF; Cooley MA; Ambrose M; Tristram SG
Year
2013
Do adaptive regulatory cells or activated T cells dominate in cystic fibrosis? (2012)$8,228
Funding
Royal Hobart Hospital Research Foundation ($8,228)
Scheme
Grant-Starter
Administered By
University of Tasmania
Research Team
Beggs S; Cooley MA; Roddam LF; Korner H; Stock D
Year
2012
2012: The Australian Society for Microbiology 2012 Annual Specific Meeting, Brisbane (2012)$600
Funding
University of Tasmania ($600)
Scheme
Grant-Conference Support Scheme
Administered By
University of Tasmania
Research Team
Roddam LF
Year
2012
Identification of a New Target for Therapy in Cystic Fibrosis Lung Infections (2011 - 2012)$20,661
Funding
Royal Hobart Hospital Research Foundation ($20,661)
Scheme
Grant-Research
Administered By
University of Tasmania
Research Team
Cooley MA; Roddam LF; Wood-Baker R; Griffin P; Beggs S
Period
2011 - 2012
PPAR-gamma as a therapeutic target in cystic fibrosis and chronic obstructive pulmonary disease (2010)$8,000
Funding
Royal Hobart Hospital Research Foundation ($8,000)
Scheme
Grant-Starter
Administered By
University of Tasmania
Research Team
Cooley MA; Roddam LF; Wood-Baker R; Reid DW
Year
2010
Clinical research equipment to accelerate research outputs in molecular and genetic studies (2010)$156,436
Funding
Royal Hobart Hospital Research Foundation ($156,436)
Scheme
Grant-Equipment
Administered By
University of Tasmania
Research Team
Reid DW; Champion AC; Roddam LF; Walters EH
Year
2010
Pseudomonas infection as an indirect cause of CF related diabetes (2009)$96,097
Funding
Australian Cystic Fibrosis Research Trust ($96,097)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Cooley MA; Roddam LF; Reid DW; Jaffe A
Year
2009
Mechanism of exacerbations in cystic fibrosis lung disease (2009 - 2011)$245,750
Funding
National Health & Medical Research Council ($245,750)
Scheme
Grant-Project
Administered By
University of Tasmania
Research Team
Reid DW; Lamont IJ; Roddam LF; Camara M; Turner P
Period
2009 - 2011
Grant Reference
544915
Mechanism of worsening lung disease in cystic fibrosis (2009)$18,850
Funding
Rebecca L Cooper Medical Research Foundation ($18,850)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Roddam LF; Reid DW; Lamont IJ; Camara M; Turner P; Cooley MA
Year
2009
The Acquisition of New Strains of Non-Typeable Haemophilus Influenzae Is The Leading Cause of Acute Exacerbations in Tasmanian COPD Patients (2007)$43,467
Funding
Clifford Craig Medical Research Trust ($43,467)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Roddam LF; Sanderson K; Wood-Baker R; Tristram SG; Haug G
Year
2007
Pseudomonas Aeruginosa Isolated from Cystic Fibrosis Patients (2006 - 2007)$127,272
Funding
Royal Hobart Hospital Research Foundation ($127,272)
Scheme
Fellowship-Postdoctoral Research
Administered By
University of Tasmania
Research Team
Roddam LF
Period
2006 - 2007
Investigation of Antibiotic Sensitivity & Virulence Factors of the Tasmanian Clonal Strain of Pseudomonas aeuruginosa Isolated from Cystic Fibrosis Patients (2005)$36,000
Funding
Clifford Craig Medical Research Trust ($36,000)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Roddam LF; Reid DW; Champion AC; Tristram SG
Year
2005

Research Supervisions

Dr Roddam has supervised several PhD and Honours students to completion.

Current supervisions

4

Past supervisions

2

Current Supervisions

DegreeTitleCommenced
PhDCross Kingdom Signaling During P.auruginosa Infection of the CF Lung Results in a Decreased Capacity of the Host to Clear the Infection2011
PhDIntrinsic Versus Disease-Mediated Defects in the Immune System of People with Cystic Fibrosis2013
PhDStudies on Stress Response Pathways in Cellular Models of Cystic Fibrosis2013
PhDThe Impact of Mechanical Ventilation on Regional Lung Injury2015

Completed Supervisions

DegreeTitleCompleted
PhDRegulation of the LIFR and gp130 Genes by the RUNX1 Transcription Factor
Candidate: Abeer Ahmed Qadi
2012
PhDInsights into the Nature and Immune Escape of a Transmissible Cancer in Tasmanian Devils
Candidate: Cesar Dario Tovar Lopez
2012