Profiles

Rahul Patel

UTAS Home Dr Rahul Patel

Rahul Patel

Lecturer/Library Liaison

Room 4007, Pharmacy Building, Sandy Bay Campus

+61 3 6226 1079 (phone)

+61 3 6226 2870 (fax)

Rahul.Patel@utas.edu.au

INFORMATION REQUIRED: A short paragraph summarising your career, any notable achievements, etc. We'll also use this text elsewhere on other websites – for example on the new Research microsite.

Career summary

Qualifications

INFORMATION REQUIRED: Qualifications, e.g. degrees, certifications. Include titles of thesis if available. Insert details of postgraduate degrees including the title, place of award and date of award, in order of highest degree to lowest.

  • PhD, University of Tasmania, Australia, YEAR, Storage-induced chemical and physical changes to enoxaparin (low molecular weight heparin)
  • MPharmSc, University of Tasmania, Australia, YEAR, Assessment of stability and activity of enoxaparin sodium by capillary

Languages (other than English)

INFORMATION REQUIRED: A list or description of any languages other than English that you know/speak. This will be helpful in attracting international collaborators.

Biography

Rahul Patel obtained both his MPharmSc and PhD degrees from the University of Tasmania. After PhD, he obtained pharmacist registration from Queensland. He is a guest editor of the Current Drug Metabolism journal and in the editorial panel of the Journal of Pediatric Biochemistry and the International Journal of Applied Biology and Pharmaceutical Technology.

He is a reviewer of a number of international journals including the Journal of Pharmaceutical Sciences, Journal of Chromatography A and Natures Protocols. The analytical technique developed by Rahul and his colleagues was recognised by the Food and Drug Administration and now the technique is included in the United State Pharmacopeia.

Rahul Patel joined as a lecturer of Pharmacological Sciences at Pharmacy, University of Tasmania in December 2009.

Research Themes

INFORMATION REQUIRED: The UTAS research theme/s to which your work relates. These are: Better Health; Creativity, Culture and Society; Marine, Antarctic and Maritime; Environment, Resources and Sustainability; and Data, Knowledge and Decisions. Describe the broad, over-arching research interest in a way that generally describes the research activity/projects that you & your group undertake, using the format provided in the example below. E.g. Joe's research aligns to the University's research theme of Better Health. His research interests include understanding how parasites and humans interact, the management of parasites and the management of parasitic disease, particularly in third world countries. Joe's research into bed bugs has spread to working with the NIH in the USA due to epidemics of the parasite infecting large parts of New York and other cities. These parasites are resistant to current treatment regimes and, as they can carry virulent diseases, an urgent remedy is required. Joe is also researching mosquito control in Africa and Asia to determine if different mechanisms of mosquito control can alter the spread of malaria. He is also working on understanding whether different herding mechanisms of cattle alter the distribution of the Tsetse fly, which is responsible for the spread of the notorious Sleeping sickness affecting millions of people worldwide.

Memberships

Professional practice

INFORMATION REQUIRED: A list or description of any professional bodies relating to your professional practice of which you are a member.

Committee associations

INFORMATION REQUIRED: A list or description of any relevant committees or associations of which you are a member.

Other

INFORMATION REQUIRED: A list or descriptions of any other memberships that relate to your work at UTAS.

Administrative expertise

INFORMATION REQUIRED: Any administrative experience or expertise the you have, e.g. managing large projects, running a faculty, etc.

Teaching

INFORMATION REQUIRED: A description or list of teaching fields, subjects, etc. This will be useful for students searching for subjects or supervisors via Google, Bing, etc.

Teaching expertise

INFORMATION REQUIRED: Any teaching experience or expertise that you have, e.g. particular subjects, degrees, post graduate teaching, course or unit design, etc.

Teaching responsibility

INFORMATION REQUIRED: The courses and/or units you are responsible for coordinating or teaching. Include links to the Course and Unit handbook.

Appointments

INFORMATION REQUIRED: A list or description of any past (< 5 years) or present appointments to research positions, bodies, etc.

Invitations

INFORMATION REQUIRED: A list or description of any past (< 5 years) or present research invitations.

View more on Dr Rahul Patel in WARP

Collaboration

INFORMATION REQUIRED: Any past or present research collaborations, e.g. with other institutes, companies or people. Enter the broad profile of national/international projects in which they are involved and the number and names of countries to which their collaborations extend.

Current projects

INFORMATION REQUIRED: A description or list of current projects. Include links to any research project websites.

Awards

INFORMATION REQUIRED: A description or list of any research-related awards.

Expertise

INFORMATION REQUIRED: Description or list of your research areas, skill, expertise, etc. This is to help media, community and non-research specialists.

Research Fields

  • Pharmaceutical Sciences (111504)
  • Pharmacology and Pharmaceutical Sciences (111599)
  • Clinical Pharmacy and Pharmacy Practice (111503)
  • Respiratory Diseases (110203)
  • Clinical Pharmacology and Therapeutics (111502)
  • Basic Pharmacology (111501)
  • Nephrology and Urology (110312)
  • Technology (109999)
  • Public Health and Health Services (111799)
  • Health, Clinical and Counselling Psychology (170106)
  • Separation Science (030108)
  • Preventive Medicine (111716)
  • Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology) (170101)
  • Analytical Biochemistry (060101)
  • Medical and Health Sciences (119999)
  • Primary Health Care (111717)
  • Traditional Chinese Medicine and Treatments (110404)
  • Clinical Social Work Practice (160701)
  • Cellular Immunology (110704)
  • Health Promotion (111712)
  • Medical Bacteriology (110801)

Research Impact

  • Public Health (excl. Specific Population Health) (920499)
  • Digestive System Disorders (920105)
  • Substance Abuse (920414)
  • Health (929999)
  • Urogenital System and Disorders (920119)
  • Expanding Knowledge in the Medical and Health Sciences (970111)
  • Clinical Health (Organs, Diseases and Abnormal Conditions) (920199)
  • Respiratory System and Diseases (incl. Asthma) (920115)
  • Health Related to Ageing (920502)
  • Immune System and Allergy (920108)
  • Blood Disorders (920101)
  • Expanding Knowledge in Technology (970110)
  • Diabetes (920104)
  • Mental Health Services (920209)
  • Veterinary Pharmaceutical Products (860999)
  • Neurodegenerative Disorders Related to Ageing (920112)
  • Hearing, Vision, Speech and Their Disorders (920107)
  • Nervous System and Disorders (920111)
  • Injury Control (920409)
  • Evaluation of Health Outcomes (920204)
  • Health Education and Promotion (920205)
  • Health and Support Services (920299)
  • Preventive Medicine (920412)

Publications

INFORMATION REQUIRED: One or two paragraphs describing your publications or publishing history. Highlight any important publications, contributions, etc. This is also a good place to indicate if you edit or are a regular contributor to any journals, etc.

Total publications

34

Journal Article

(25 outputs)
YearCitationAltmetrics
2015Patel RP, Wanandy T, Zani RS, Jose MD, Shastri M, et al., 'Stability of trimethoprim in newly formulated liquid dosage form', Journal of Pharmacy Practice and Research, 45 pp. 1-5. ISSN 1445-937X (2015) [Refereed Article]

DOI: 10.1002/jppr.1127 [eCite] [Details]

Co-authors: Wanandy T; Shastri M

Tweet

2015Lean Q, Eri RD, Fitton JH, Patel RP, Gueven N, 'Fucoidan Extracts Ameliorate Acute Colitis', PL o S One pp. 1-18. ISSN 1932-6203 (2015) [Refereed Article]

DOI: 10.1371/journal.pone.0128453 [eCite] [Details]

Co-authors: Lean Q; Eri RD; Gueven N

Tweet

2015Lu W, Ferguson SG, Nichols D, Patel RP, Jacobson GA, 'Determination of Nicotine in Cartridge-Based Electronic Cigarettes', Analytical Letters ISSN 0003-2719 (2015) [Refereed Article]

DOI: 10.1080/00032719.2015.1048349 [eCite] [Details]

Co-authors: Lu W; Ferguson SG; Nichols D; Jacobson GA

Tweet

2015Ng H, Patel RP, Bruno R, Latham R, Wanandy T, et al., 'Filtration of crushed tablet suspensions has potential to reduce infection incidence in people who inject drugs', Drug and Alcohol Review, 34, (1) pp. 67-73. ISSN 0959-5236 (2015) [Refereed Article]

DOI: 10.1111/dar.12196 [eCite] [Details]

Co-authors: Ng H; Bruno R; Latham R; Wanandy T; McLean S

Tweet

2015Patel RP, Li K, Shastri M, Wanandy T, 'Stability of ampicillin and amoxicillin in peritoneal dialysis solutions', American Journal of Health-System Pharmacy, 72 pp. 13-14. ISSN 1079-2082 (2015) [Letter or Note in Journal]

DOI: 10.2146/ajhp130717 [eCite] [Details]

Co-authors: Li K; Shastri M; Wanandy T

Tweet

2015Patel RP, Li K, Shastri M, Wanandy T, Jose MD, 'Stability of ampicillin and amoxicillin in peritoneal dialysis solutions', American Journal of Health-System Pharmacy, 72 pp. 13-14. ISSN 1695-0674 (2015) [Letter or Note in Journal]

DOI: 10.2146/ajhp130717 [eCite] [Details]

Co-authors: Shastri M; Jose MD

Tweet

2015Lean QY, Eri RD, Randall-Demllo S, Sohal SS, Stewart N, et al., 'Orally Administered Enoxaparin Ameliorates Acute Colitis by Reducing Macrophage-Associated Inflammatory Responses', PL o S One, 10, (7) Article e0134259. ISSN 1932-6203 (2015) [Refereed Article]

DOI: 10.1371/journal.pone.0134259 [eCite] [Details]

Co-authors: Lean QY; Eri RD; Randall-Demllo S; Sohal SS; Stewart N; Peterson GM

Tweet

2015Ramdas S, Yousaf F, Shastri M, Wanandy ST, Zaidi STR, et al., 'Stability of daptomycin in peritoneal dialysis solutions packaged in dual-compartment infusion bags', European Journal of Hospital Pharmacy - Science and Practice pp. 1-4. ISSN 2047-9956 (2015) [Refereed Article]

DOI: 10.1136/ejhpharm-2015-000651 [eCite] [Details]

Co-authors: Shastri M; Wanandy ST; Zaidi STR; Khandagale M; Jose MD

Tweet

2015Shastri M, Stewart N, Eapen M, Peterson GM, Razi Zaidi ST, et al., 'Opposing Effects of Low Molecular Weight Heparins on the Release of Inflammatory Cytokines from Peripheral Blood Mononuclear Cells of Asthmatics', PL o S One pp. 1-19. ISSN 1932-6203 (2015) [Refereed Article]

DOI: 10.1371/journal.pone.0118798 [eCite] [Details]

Citations: Scopus - 2

Co-authors: Shastri M; Stewart N; Eapen M; Peterson GM; Razi Zaidi ST; Guven N; Sohal SS

Tweet

2015Shastri M, Stewart NJ, Horne J, Peterson GM, Gueven N, et al., 'In-Vitro Suppression of IL-6 and IL-8 Release from Human Pulmonary Epithelial Cells by Non-Anticoagulant Fraction of Enoxaparin', PL o S One pp. 1-23. ISSN 1932-6203 (2015) [Refereed Article]

DOI: 10.1371/journal.pone.0126763 [eCite] [Details]

Co-authors: Shastri M; Stewart NJ; Horne J; Peterson GM; Gueven N; Sohal SS

Tweet

2015Shastri M, Stewart NJ, Horne J, Razi Zaidi ST, Sohal SS, et al., 'Non-Anticoagulant Fractions of Enoxaparin Suppress Inflammatory Cytokine Release from Peripheral Blood Mononuclear Cells of Allergic Asthmatic Individuals', PL o S One, 10, (6) Article e0128803. ISSN 1932-6203 (2015) [Refereed Article]

DOI: 10.1371/journal.pone.0128803 [eCite] [Details]

Co-authors: Shastri M; Stewart NJ; Horne J; Razi Zaidi ST; Sohal SS; Peterson GM; Korner H; Gueven N

Tweet

2015Lean Q, Gueven N, Eri RD, Bhatia R, Sohal SS, et al., 'Herapins in ulcerative colitis: proposed and potential reasons for inconsistent clinical outcomes', Expert Review of Clinical Pharmacology, 8, (6) ISSN 1751-2433 (In Press) [Refereed Article]

DOI: 10.1586/17512433.2015.1082425 [eCite] [Details]

Co-authors: Lean Q; Gueven N; Eri RD; Sohal SS; Stewart N; Peterson GM

Tweet

2014Lean QY, Patel RP, Stewart N, Sohal SS, Guven N, 'Identification of pro-and anti-proliferative oligosaccharides of heparins', Integrative Biology, 6, (1) pp. 90 - 99. ISSN 0974-2816 (2014) [Refereed Article]

DOI: 10.1039/c3ib40206a [eCite] [Details]

Co-authors: Lean QY; Stewart N; Sohal SS; Guven N

Tweet

2014Nowrin K, Sohal SS, Peterson G, Patel R, Walters EH, 'Epithelial-mesenchymal transition as a fundamental underlying pathogenic process in COPD airways: fibrosis, remodeling and cancer', Expert Reviews in Respiratory Medicine, 8, (5) pp. 547-559. ISSN 1747-6348 (2014) [Refereed Article]

DOI: 10.1586/17476348.2014.948853 [eCite] [Details]

Citations: Scopus - 2Web of Science - 3

Co-authors: Nowrin K; Sohal SS; Peterson G; Walters EH

Tweet

2014Patel RP, Shastri MD, Bakkari M, Wanandy T, Jose MD, 'Stability of the combination of ceftazidime and cephazolin in icodextrin or pH neutral peritoneal dialysis solution', Peritoneal Dialysis International, 34, (2) pp. 212-218. ISSN 0896-8608 (2014) [Refereed Article]

DOI: 10.3747/pdi.2013.00034 [eCite] [Details]

Citations: Scopus - 1Web of Science - 1

Co-authors: Shastri MD; Wanandy T; Jose MD

Tweet

2014Shastri M, Peterson GM, Stewart NJ, Sohal SS, Patel RP, 'Non-anticoagulant derivatives of heparin for the management of asthma: distant dream or close reality?', Expert Opinion on Investigational Drugs: Authoritative Analysis of Randd Trends, 23, (3) pp. 357-373. ISSN 1354-3784 (2014) [Refereed Article]

DOI: 10.1517/13543784.2014.866092 [eCite] [Details]

Citations: Scopus - 5Web of Science - 5

Co-authors: Shastri M; Peterson GM; Stewart NJ; Sohal SS

Tweet

2013Patel RP, Shastri M, Wanandy ST, Jose MD, 'Physical and chemical stability of ceftazidime and cefazolin in peritoneal dialysis solutions packaged in dual-chamber infusion bags', American Journal of Health-System Pharmacy, 70, (17) pp. 1477-1478. ISSN 1079-2082 (2013) [Letter or Note in Journal]

DOI: 10.2146/ajhp120692 [eCite] [Details]

Co-authors: Shastri M; Wanandy ST; Jose MD

Tweet

2013Patel RP, Wanandy S, Loring S, Johns C, Hutchinson J, et al., 'Stability of diluted iron polymaltose in PVC infusion bags', Journal of Pharmacy Practice and Research, 43, (2) pp. 112-116. ISSN 1445-937X (2013) [Refereed Article]

[eCite] [Details]

Co-authors: Wanandy S; Johns C; Hutchinson J; Shastri M

2013Shastri MD, Johns C, Hutchinson JP, Khandagale M, Patel RP, 'Ion exchange chromatographic separation and isolation of oligosaccharides of intact low-molecular-weight heparin for the determination of their anticoagulant and anti-inflammatory properties', Analytical and Bioanalytical Chemistry, 405, (18) pp. 6043-6052. ISSN 1618-2650 (2013) [Refereed Article]

DOI: 10.1007/s00216-013-6996-9 [eCite] [Details]

Citations: Scopus - 5Web of Science - 5

Co-authors: Shastri MD; Johns C; Hutchinson JP; Khandagale M

Tweet

2012Patel PK, Patel RP, Brandon S, McLean S, Bruno R, et al., 'Effects of Filtration on the Presence of Particulate and Oxycodone Content of Injections Prepared from Crushed OxyContin® Tablets', Current Drug Safety, 7, (3) pp. 218-224. ISSN 1574-8863 (2012) [Refereed Article]

DOI: 10.2174/157488612803251298 [eCite] [Details]

Citations: Scopus - 2

Co-authors: Brandon S; McLean S; Bruno R; de Graaff B

Tweet

2009Patel R, Narkowicz CK, Jacobson GA, 'Investigation of the effect of heating on the chemistry and antifactor Xa activity of enoxaparin', Journal of Pharmaceutical Science, 98, (5) pp. 1700 - 1711. ISSN 0022-3549 (2009) [Refereed Article]

DOI: 10.1002/jps.21556 [eCite] [Details]

Citations: Scopus - 7Web of Science - 7

Co-authors: Narkowicz CK; Jacobson GA

Tweet

2009Patel R, Narkowicz CK, Jacobson GA, 'Investigation of freezing- and thawing-induced biological, chemical, and physical changes to enoxaparin solution', Journal of Pharmaceutical Science, 98, (3) pp. 1118 - 1128. ISSN 0022-3549 (2009) [Refereed Article]

DOI: 10.1002/jps.21483 [eCite] [Details]

Citations: Scopus - 6Web of Science - 7

Co-authors: Narkowicz CK; Jacobson GA

Tweet

2009Patel R, Narkowicz CK, Jacobson GA, 'Effective reversed-phase ion pair high-performance liquid chromatography method for the separation and characterization of intact low-molecular-weight heparins ', Analytical Biochemistry, 387, (1) pp. 113-121. ISSN 0003-2697 (2009) [Refereed Article]

DOI: 10.1016/j.ab.2009.01.007 [eCite] [Details]

Citations: Scopus - 19Web of Science - 19

Co-authors: Narkowicz CK; Jacobson GA

Tweet

2008Patel R, Narkowicz CK, Hutchinson J, Hilder EF, Jacobson GA, 'A simple capillary electrophoresis method for the rapid separation and determination of intact low molecular weight and unfractionated heparins', Journal of Pharmaceutical and Biomedical Analysis, 46, (1) pp. 30-35. ISSN 0731-7085 (2008) [Refereed Article]

DOI: 10.1016/j.jpba.2007.10.009 [eCite] [Details]

Citations: Scopus - 48Web of Science - 41

Co-authors: Narkowicz CK; Hutchinson J; Hilder EF; Jacobson GA

Tweet

2008Patel R, Narkowicz CK, Jacobson GA, 'In vitro stability of enoxaparin solutions (20 mg/mL) diluted in 4% glucose', Clinical Therapeutics, 30, (10) pp. 1880-1885. ISSN 0149-2918 (2008) [Refereed Article]

DOI: 10.1016/j.clinthera.2008.10.014 [eCite] [Details]

Citations: Scopus - 2Web of Science - 2

Co-authors: Narkowicz CK; Jacobson GA

Tweet

Conference Publication

(8 outputs)
YearCitationAltmetrics
2011Patel P, Patel RP, McLean SR, Bruno RB, 'Effects of Filtration on the Presence of Particulate and Buprenorphine Content of Injections Prepared from Crushed Subutex® Tablets', Drug and Alcohol Review, 13-16 November 2011, Hobart, Australia, pp. 72. ISSN 0959-5236 (2011) [Conference Extract]

[eCite] [Details]

Co-authors: McLean SR; Bruno RB

2010McLean SR, Brandon S, Bruno RB, de Graaff B, Patel RP, 'Reducing harm from pharmaceutical opioid injection: The importance and effectiveness of filters', Drug and Alcohol Review, 28 November -1 December 2010, Canberra, Australia, pp. A51. (2010) [Conference Extract]

[eCite] [Details]

Co-authors: McLean SR; Brandon S; Bruno RB; de Graaff B

2010McLean SR, Brandon S, de Graaff B, Bruno RB, Patel RP, 'Injecting OxyContin: What is the harm reduction eveidence?', Proceedings of ATDC 2010, 18-20 October 2010, Hobart, pp. 1. (2010) [Conference Extract]

[eCite] [Details]

Co-authors: McLean SR; Brandon S; de Graaff B; Bruno RB

2009Patel RP, Narkowicz CK, Jacobson GA, 'A low-volume microtitre plate assay for determination of the AFXa activity of enoxaparin', Australasian Pharmaceutical Science Association Annual Conference Aus-CRS Symposium Program and Abstract book, 9-11 December 2009, Wrest Point Convention Centre, Hobart Tasmania, pp. 140. ISBN 978-0-646-52257-9 (2009) [Conference Extract]

[eCite] [Details]

Co-authors: Narkowicz CK; Jacobson GA

2008Patel R, 'Stability enhancement ofl diluted enoxaparin sodium at paediatric dosage', Teams for tomorrow, 6-9 December 2008, Canberra, ACT, pp. 108. (2008) [Conference Extract]

[eCite] [Details]

2007Patel R, Narkowicz CK, Jacobson GA, 'The effect of heating on the chemistry and biological activity of enoxaparin', Australian Pharmaceutical Science Association, 8-11 December 2007, Manly NSW, pp. 205. ISBN 978-0-646-48458-7 (2007) [Conference Edited]

[eCite] [Details]

Co-authors: Narkowicz CK; Jacobson GA

2007Patel R, Narkowicz CK, Jacobson GA, 'The effects of freezing and thawing on the AFXa activity of enoxaparin solution', Australian Pharmaceutical Science Association, 8-11 December 2007, Manly NSW, pp. 205. ISBN 978-0-646-48458-7 (2007) [Conference Edited]

[eCite] [Details]

Co-authors: Narkowicz CK; Jacobson GA

2007Patel R, Narkowicz CK, Jacobson GA, 'Separation and characterisation of different low-molecular-weight heparins by reversed-phase ion-interaction high-performance liquid chromatography', Proceedings of the APSA Annual Conference, 8-11 December 2007, Manly NSW, pp. 205. ISBN 978-0-646-48458-7 (2007) [Conference Extract]

[eCite] [Details]

Co-authors: Narkowicz CK; Jacobson GA

Thesis

(1 outputs)
YearCitationAltmetrics
2007Patel R, 'Enoxaparin: physicochemical investigations into the effects of freezing and heating' (2007) [PhD]

[eCite] [Details]

Grants & Funding

INFORMATION REQUIRED: One or two paragraphs about your grants & projects history or achievements. Highlight any current or important projects or grants.

Funding Summary

Number of grants

12

Total funding

$267,452

Projects

Fucoidan and gut health (2015)$100,000
Description
This project represents industry interaction to develop Marinovas fucoidan extract for gut health.
Funding
Department of Industry and Science ($50,000)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Guven N; Davis E; Eri RD; Patel RP
Year
2015
Non anticoagulant molecules of heparin for the management of ulcerative colitis (2015)$15,000
Description
This project aims to achieve the identification and evaluation of non-anticoagulant molecules of heparin that are responsible for the observed beneficial effects of heparin in patients with ulcerative colitis as well as to compare potential biomarkers in a preclinical muse model with ulcerative colitis patients.
Funding
Royal Hobart Hospital Research Foundation ($15,000)
Scheme
Grant-Clinical Research
Administered By
University of Tasmania
Research Team
Patel RP; Guven N; Eri RD; Bhatia R
Year
2015
Novel molecules of heparin for the management of asthma (2014)$4,998
Description
Aim: In an international first, this project aims to achieve the evaluation and identification of heparin molecules that inhibit the effect of several important inflammatory mediators involved in the pathogenesis of asthma, without possessing significant anticoagulant effect, with a view towards examining the efficacy of identified molecules in patients with asthma. Methodology: Heparin molecules will be separated and isolated using an ion-chromatography technique. Participants will attend the clinic where 50mL of blood will be taken by a qualified nurse. Mononuclear cells will be isolated from the collected blood. Then the cells will be activated to produce inflammatory mediators in the presence or absence of heparin fractions. Outcome: This research will evaluate and identify the novel molecules responsible for the anti-asthmatic activity of the parent heparin. This study would provide better insight into the mechanism(s) of heparin for its anti-asthmatic activity. It could open new avenues for the development of a heparin formulation with high anti-asthmatic properties but devoid of any anticoagulant activity. This could potentially resolve the safety and non-compliance issues objected upon in previous clinical trials.
Funding
Royal Hobart Hospital Research Foundation ($4,998)
Scheme
Grant-Starter
Administered By
University of Tasmania
Research Team
Hunter CJ; Patel RP; Stewart NJ; Sohal SS
Year
2014
Novel Fractions of Heparin for the Treatment of Ulcerative Colitis (2014)$14,500
Funding
University of Tasmania ($14,500)
Scheme
Grant-Research Enhancement (REGS)
Administered By
University of Tasmania
Research Team
Patel RP
Year
2014
Fucoidan extract in the treatment of ulcerative colitis in an animal model (2013)$2,810
Description
Brown algal extracts, in particular those containing fucoidan have been shown to have potential applications in a number of health indications such as prediabetes, immunomodulation, cardiovascular disease, inflammation and gut health. With advances in technology, fucoidan extracts from brown seaweed can now be produced successfully on a commercial scale. These types of extracts are beginning to become more prevalent as ingredients in western dietary supplement markets. However, for the extracts to successfully enter this market, efficacy, safety and provenance must be proven to help gain acceptance. With this in mind, the objectives of this project include the following: to establish the efficacy of high purity fucoidan extract from Fucusvesiculosus in the treatment of ulcerative colitis in an animal model; and to compare the efficacy of the routes of administration of Fucusvesiculosus fucoidan in treating ulcerative colitis with particular reference to oral and intra-peritoneal dosages.
Funding
Marinova Pty Ltd ($2,810)
Scheme
Contract Research
Administered By
University of Tasmania
Research Team
Peterson GM; Guven N; Patel RP
Year
2013
The physical and chemical stability of amoxicillin, daptomycin and quinupristin/dalfopristin in Dianeal, Extraneal or Fresenius peritonieal dialysis solution under three different storage conditions (2013)$9,090
Description
The physicochemical stability of amoxicillin, daptomycin and quinupristin/dalfopristin in peritoneal dialysis solution is currently unknown. This study will determine the stability of these antibiotics in various types of PD solutions and will supply crucial information to guide current clinical practice and to provide a more convenient service for patients with end stage renal disease.
Funding
Royal Hobart Hospital Research Foundation ($9,090)
Scheme
Grant-Research
Administered By
University of Tasmania
Research Team
Wanandy ST; Patel RP; Jose MD
Year
2013
Fucoidan and marine polyphloroglucinols (2012 - 2014)$85,000
Description
Brown algal extracts, in particular those containing fucoidan and marine polyphloroglucinols, have been shown to have potential applications in a number of health indications such as pre-diabetes, immunomodulation, cardiovascular disease and inflammation. With advances in technology, fucoidan and marine polyphloroglucinol extracts from brown seaweed can now be produced successfully on a commercial scale. These types of extracts are beginning to become more prevalent as ingredients in western dietary supplement markets. However, for the extracts to successfully enter this market, efficacy, safety and provenance must be proven. With this in mind, the objectives of this PhD project include the following: to establish a generic analytical method that can be used to fingerprint and quantify fucoidan concentrations in solution, serum and urine; to determine the ability of a commercially available fucoidan/polyphloroglucinol extract (Maritech Synergy) to inhibit the uptake of glucose via an acute human study; to assess the effects of Maritech Synergy on health indications including glucose control, insulin sensitivity and pre-diabetes in a human setting; and to further the understanding of fucoidan and its metabolism.
Funding
Marinova Pty Ltd ($85,000)
Scheme
Clinical Trial
Administered By
University of Tasmania
Research Team
Peterson GM; Patel RP; Bereznicki LRE
Period
2012 - 2014
Identification and Screening of Heparin components for therapeutical Potential in the management of Asthma (2011)$16,218
Funding
University of Tasmania ($16,218)
Scheme
Grant-Institutional Research Scheme
Administered By
University of Tasmania
Research Team
Patel RP
Year
2011
Development of a Simple and Effective Ion-chromatagraphic Analysis for the Separation and Identification of Non-anticoagulant fractions of Enoxaparin (2011)$6,950
Funding
University of Tasmania ($6,950)
Scheme
Grant-Cross Theme
Administered By
University of Tasmania
Research Team
Patel RP; Hutchinson J; Johns CA; Jacobson GA; Narkowicz CK; Peterson GM
Year
2011
Investigations of the Chemical and Physical Stability of Iron Polymaltose Intravenous Infusion (2011)$6,364
Funding
Royal Hobart Hospital Research Foundation ($6,364)
Scheme
Grant-Research
Administered By
University of Tasmania
Research Team
Wanandy ST; Patel RP; Randall C; Jacobson GA; Holmes SE; Hutchinson C; Johns CA
Year
2011
Investigations into the Effect of Filtration on Drug Recovery, Particle and Bacterial Contents of Injections Prepared from Oxycodone or Buprenorphine Tablets (2010)$5,000
Funding
University of Tasmania ($5,000)
Scheme
Grant-New Appointees Research Grant Scheme (NARGS)
Administered By
University of Tasmania
Research Team
Patel RP
Year
2010
International Conference and Exhibition on Analytical and Bioanalytical Techniques - India, 2010 (2010)$1,522
Funding
University of Tasmania ($1,522)
Scheme
Grant-Conference Support Scheme
Administered By
University of Tasmania
Research Team
Patel RP
Year
2010

Research Supervisions

INFORMATION REQUIRED: One or two paragraphs describing your supervisions history. This is also good place to indicate if you are looking for any HDR candidates (include things such as what qualifications or experience you are looking for, and what projects are available).

Current supervisions

6

Current Supervisions

DegreeTitleCommenced
PhDAnti-Asthmatic Activity of Heparin2011
PhDTherapeutic Potential of Heparin in the Management of Ulcerative Colitis2012
MastersDrivers of Epithelial Mesenchymal Transition (EMT) in Chronic Obstructive Pulmonary Disease (COPD)2013
PhDThe Safety and Efficacy of Electronic-Cigarettes as Cessation Aids and the use of Electronic-Cigarettes by Smokers2013
MastersDevelopment of Analytical Techniques for the Separation and Characterisation of Biologicaly-Active Complicated Polysaccharides2013
MastersInvestigation of oral bioavailability and plasma pharmacokinetics of different oral formulations of glucosamine2014