Profiles

Lila Landowski

UTAS Home Doctor Lila Landowski
Lila Landowski

Lila Landowski

Junior Research Fellow

MSP, Hobart CBD Campuses

Dr Lila Landowski is a neuroscientist with the School of Medicine, as well as a science communicator and science advocate. She is the 2015 Premier's Young Achiever of the Year, and a finalist for Young Australian of the Year (Tasmania) in 2016. Lila is currently investigating stroke and nerve regeneration. Lila regularly engages with the community through science segments on ABC radio, public talks and in print and digital media. She taught into courses at the University of Tasmania for eight years, working across various subjects for Bachelor of Medicine, Bachelor of Medical Research, Biotechnology, Pharmacy and Science students; as well as coordinating units in the Bachelor of Dementia Care.

Biography

As a neuroscientist, Lila’s research expertise is in axon guidance, neural repair mechanisms and therapeutic development for nerve damage. In 2014, after completing her PhD at the Menzies Research Institute Tasmania, Lila trained at the Peripheral Nerve lab at the Mayo Clinic to cement her status as an emerging leader in the field of peripheral nerve injury.  She was recruited to teach and coordinate neuroscience units at the Wicking Dementia Centre at the same time. In recent years, her research focus has shifted from peripheral neuropathy to stroke. She us currently a postdoctoral fellow in the lab of Professor David Howells. For several months (from August 2016 - April 2017), Lila spent time as a visiting scholar at the Florey Institute’s Melbourne Brain Centre (Austin Hospital, Melbourne), developing surgical skills and a novel model of stroke to bring back to UTAS. With the support of a $450,000 investment from the Royal Hobart Hospital Research Foundation, her foremost research goal is to transform the success of pre-clinical stroke research.

Lila has 8 years teaching experience with the University of Tasmania, primarily in undergraduate medicine. Expanding on these roles, she coordinated units in basic neuroanatomy and pathology of dementia for at the Wicking Dementia Centre Academy.

Lila has a strong personal focus on the importance of science communication, public outreach, and community health and well-being.

Career summary

Qualifications

  • PhD - LRP receptors in a novel mechanism of axon pathfinding and peripheral nerve regeneration. Menzies Research Institute, Australia (2014)
  • BMedRes (1st Class Hons) - Metallothionein II and III; novel chemotactic cues in growth cones. Menzies Research Institute, Australia (2009)
  • BMedRes. University of Tasmania, Australia (2008)

Memberships

Professional practice

  • Society for Neuroscience (2012-present)
  • Australian Neuroscience Society (2010-present)
  • Golden Key International Honours Society (2006-present)

Administrative expertise

Unit coordination (maximum class size 577 students).

Teaching

Teaching expertise

  • CAD304 Negotiated Project in Understanding Dementia (Tutor)
  • CAD110 Negotiated Study in Understanding Dementia (Unit Coordinator)
  • CAD101 Introduction to the brain, dementia, and ageing (Unit Coordinator)
  • CAM304 Neuroanatomy (Practical Demonstrator)
  • CAM101 Histology (Practical Demonstrator)
  • CAM102 Histology (Practical Demonstrator)
  • CAM202 Histology (Practical Demonstrator)
  • CHG105/CHG111 Human Biology (Practicals, Tutorials and Lectures)
  • CHG106/CHG112 Human Biology (Practicals, Tutorials and Lectures)
  • CAM301 Introduction to lab based developmental Neuroscience (Teaching lab techniques)
  • CBA343 Introduction to lab based developmental Neuroscience (Teaching lab techniques)
  • Understanding Dementia Massive Open Online Course
  • Brain dissection and anatomy; Introduction to Medical Science and Neuroscience

View more on Dr Lila Landowski in WARP

Expertise

  • Stroke
  • Nerve regeneration
  • Axon guidance
  • Peripheral Neuropathy
  • Chemotherapy-induced Neuropathy
  • Diabetic Neuropathy
  • Neurodevelopment
  • Histology (microanatomy)

Research Themes

Lila’s research aligns to the theme of Better Health.

Her current research portfolio has two major projects (stroke and fatigue)

Stroke - The cost of stroke in the developed world is up to an estimated A$1475 billion a year. Despite decades of research, drug development for stroke has failed repeatedly. Of the 1000+ promising therapeutics developed for stroke in animal models, only one is used clinically. Even then, the utility and applicability of this drug is limited. Research from our laboratory suggests that the primary reason for the failure of translation arises from flaws with the stroke models themselves. However, we have devised a clever solution to overcome these limitations; my role is to establish this new gold-standard model of stroke. These improvements are critical: they will increase the face validity of stroke modelling, allow us to test hypotheses critical to our understanding of stroke biology and improve the success of preclinical translational stroke research. We estimate that even modest improvements in stroke modelling might achieve savings of ~$1.9bn in the estimated $14.6bn research cost of developing a new stroke therapy.

Fatigue - Fatigue is much more than just a sense of tiredness. It is also a debilitating symptom of many diseases and disorders, hampering peoples’ ability to perform the simplest of daily activities. The underlying mechanism of fatigue is unknown. We hypothesise that fatigue is ultimately a disorder resulting from an energy deficit in the brain.

Neonatal versus adult nerve regeneration – Neonate and young children's brains have a remarkable ability to recover from neuronal injury. Understanding this process will have very important implications for improving recovery from neurological diseases and injury in adults.

Neuropathy - Development of a therapeutic for chemotherapy induced neuropathy. Imagine surviving cancer, only to suffer from debilitating pain for the rest of your life? Unfortunately, this is a common reality for many people who have had chemotherapy for cancer. We have developed compelling evidence that the protein metallothionein can accelerate regeneration of peripheral nerves.  Lila would like to identify whether metallothionein can be used as prophylactic agent to prevent or reduce chemotherapy-induced neuropathy.

Awards

  • Young Australian of the Year – finalist (TAS) (2016)
  • University of Tasmania Teaching Merit Certificate (2015, 2016)
  • Premier’s Young Achiever of the Year (2015)
  • Southern Cross Tasmanian Young Achiever’s Award: Winner, Health&Wellbeing award (2015)
  • Southern Cross Tasmanian Young Achiever’s Award: Winner, Career kickstart award (2014)
  • Southern Cross Tasmanian Young Achiever’s Award: Semi-finalist, Health&Wellbeing award (2014)
  • Australian Neuroscience Society travel award (2010, 2011, 2014)
  • Australian Postgraduate Award (2010 - 2013)
  • Dako Immunohistochemistry Postgraduate Research Bursary (2012)
  • Graduate Research Candidate Conference Fund travel award (2012)
  • Cancer Council “Seize the day” award (2012)
  • Southern Cross Tasmanian Young Achiever’s Award: Semi Finalist, Science & Technology (2011)
  • AusBiotech-GSK Student Excellence Awards: State finalist (2011)

Fields of Research

  • Cellular Nervous System (110902)
  • Peripheral Nervous System (110905)
  • Central Nervous System (110903)
  • Medical and Health Sciences (119999)
  • Proteins and Peptides (030406)
  • Nutrition and Dietetics (111199)
  • Biological Sciences (069999)
  • Health Promotion (111712)
  • Medicine, Nursing and Health Curriculum and Pedagogy (130209)
  • Neurology and Neuromuscular Diseases (110904)

Research Objectives

  • Nervous System and Disorders (920111)
  • Expanding Knowledge in the Medical and Health Sciences (970111)
  • Health Education and Promotion (920205)
  • Learner and Learning Processes (930102)
  • Expanding Knowledge in the Biological Sciences (970106)
  • Allied Health Therapies (excl. Mental Health Services) (920201)
  • Cancer and Related Disorders (920102)
  • Diabetes (920104)

Publications

Total publications

62

Journal Article

(3 outputs)
YearCitationAltmetrics
2016Auderset L, Landowski LM, Foa L, Young KM, 'Low density lipoprotein receptor related proteins as regulators of neural stem and progenitor cell function', Stem Cells International Article 2108495. ISSN 1687-9678 (2016) [Refereed Article]

DOI: 10.1155/2016/2108495 [eCite] [Details]

Citations: Scopus - 9Web of Science - 10

Co-authors: Foa L; Young KM

Tweet

2016Landowski LM, Dyck PJB, Engelstad J, Taylor BV, 'Axonopathy in peripheral neuropathies: Mechanisms and therapeutic approaches for regeneration', Journal of Chemical Neuroanatomy, 76, (Pt A) pp. 19-27. ISSN 0891-0618 (2016) [Refereed Article]

DOI: 10.1016/j.jchemneu.2016.04.006 [eCite] [Details]

Citations: Scopus - 8Web of Science - 8

Co-authors: Taylor BV

Tweet

2015Landowski LM, Pavez MP, Brown LS, Gasperini R, Taylor BV, et al., 'Low-density lipoprotein receptor-related proteins in a novel mechanism of axon guidance and peripheral nerve regeneration', Journal of Biological Chemistry, 291, (3) pp. 1092-1102.. ISSN 1083-351X (2015) [Refereed Article]

DOI: 10.1074/jbc.M115.668996 [eCite] [Details]

Citations: Scopus - 9Web of Science - 7

Co-authors: Pavez MP; Brown LS; Gasperini R; Taylor BV; West AK; Foa L

Tweet

Conference Publication

(8 outputs)
YearCitationAltmetrics
2016Goldberg L, Carr A, Canty A, Klekociuk S, Ward D, et al., 'Making neuroscience important and relevant: Online learning in an innovative Bachelor of Dementia Care program', E-Learning, E-Education, and Online Training: Second International Conference, eLEOT 2015, 16-18, 2015, Novedrate, Italy, pp. 84-91. ISBN 978-3-319-28882-6 (2016) [Refereed Conference Paper]

DOI: 10.1007/978-3-319-28883-3 [eCite] [Details]

Co-authors: Goldberg L; Carr A; Canty A; Klekociuk S; Ward D; King C; McInerney F; Vickers J

Tweet

2015Landowski LM, Pavez MP, Gasperini RJ, Taylor BVM, West AK, et al., 'Low-density lipoprotein receptor-related proteins guide navigating PNS axons', 2015 PNS Meeting, 28 June - 2 July, 2015, Quebec City, Canada (2015) [Conference Extract]

[eCite] [Details]

Co-authors: Pavez MP; Gasperini RJ; Taylor BVM; West AK; Foa LC

2014Canty A, Burke KF, Carr AR, Ceperkovic H, Elliott Kate-Ellen, et al., 'Online Learning and Aspirations in the Bachelor of Dementia Care degree', Aspirations Matter 2014, 5th December, 2014, Launceston, Tasmania (2014) [Conference Extract]

[eCite] [Details]

Co-authors: Canty A; Burke KF; Carr AR; Ceperkovic H; Elliott Kate-Ellen; Goldberg LR; Grace A; Jestrimski JW; Kleinig KL; Minstrell ML; Price AD

2014Landowski L, Pavez MP, Gasperini R, Taylor BV, West AK, et al., 'LRP receptors in a novel mechanism of axon pathfinding and peripheral nerve regeneration', Proceedings of Neuroscience 2014, 15-19 November 2015, Washington DC (2014) [Conference Extract]

[eCite] [Details]

Co-authors: Pavez MP; Gasperini R; Taylor BV; West AK; Foa L

2014Landowski LM, Taylor BVM, West AK, Foa LC, 'Identification of novel neurotrophic-like factors: a candidate for promoting nerve regeneration in neuropathy', ANS Adelaide 2014, Jan 28-31, 2014, Adelaide, Australia (2014) [Conference Extract]

[eCite] [Details]

Co-authors: Taylor BVM; West AK; Foa LC

2012Landowski LM, Gasperini RJ, Taylor BVM, West AK, Foa LC, 'Metallothionein I/II induces growth cone chemotaxis via an LRP 1 and LRP 2 dependent mechanism', Neuroscience 2012, 13-17 October, 2012, New Orleans, Louisiana (2012) [Conference Extract]

[eCite] [Details]

Co-authors: Gasperini RJ; Taylor BVM; West AK; Foa LC

2012Landowski LM, Gasperini RJ, Taylor BVM, West AK, Foa LC, 'Metallothionein I/II induces growth cone chemotaxis via an LRP 1 and LRP 2 dependent mechanism', Neuroscience 2012, 13-17 October, 2012, New Orleans, Louisiana (2012) [Conference Extract]

[eCite] [Details]

Co-authors: Gasperini RJ; Taylor BVM; West AK; Foa LC

2011Landowski LM, Gasperini RJ, Small DH, Taylor BVM, West AK, et al., 'Metallothionein I/II and metallothionein III induce growth cone chemotaxis via disparate mechanisms', Australian Neuroscience Society 31st Annual Meeting, 31 Jan - 3 Feb, Auckland, New Zealand (2011) [Conference Extract]

[eCite] [Details]

Co-authors: Gasperini RJ; Small DH; Taylor BVM; West AK; Foa LC

Other Creative Work

(2 outputs)
YearCitationAltmetrics
2018Landowski LM, 'Dementia trials bring hope', ABC Radio National, ABC Radio National website, and on air (2018) [Minor Creative Work]

[eCite] [Details]

Tweet

2017Landowski LM, 'Modern Science, Modern Life', Text Publishing (Melbourne, Australia), Griffith Review, pp. 1 (2017) [Minor Creative Work]

[eCite] [Details]

Other Public Output

(49 outputs)
YearCitationAltmetrics
2018Landowski LM, 'Vision for Hobart city deal gets shot in the arm', The Mercury, Online, 16 January 2018 (2018) [Newspaper Article]

[eCite] [Details]

Tweet

2018Landowski LM, 'Inside the Brain - a journey inside the brain and how we come to be who we are. Part 1, The Amygdala', Evenings with Melanie Tait, 936 ABC Hobart, 21 January 2018 (2018) [Media Interview]

[eCite] [Details]

2018Landowski LM, 'Sexuality and neuroscience, the sexuality of the stars, and the curious sexualities of the sex industry', Interview for the podcast by Stilgherrian, Online, 27 February 2018 (2018) [Media Interview]

[eCite] [Details]

2018Landowski LM, 'Scientists have developed a new blood test that can detect Alzheimer's disease up to 20 years before symptoms begin. But there's still no cure for dementia, so why do we care?', Interview with ABC Radio Hobart, Drive program, Australia, 31 January 2018 (2018) [Media Interview]

[eCite] [Details]

2018Landowski LM, 'Beaker Street launch at TMAG. Dr Landowski discusses the effect of stress on the brain, and how to fix it with some simple life hacks', Afternoons with Lucie Cutting and Natasha Mitchell of ABC Radio National, Australia, 8 August 2018 (2018) [Media Interview]

[eCite] [Details]

2017Landowski LM, 'She'll be apples: Tasmanian women consider the future', Island Magazine, Australia, 151, p. 52. (2017) [Magazine Article]

[eCite] [Details]

2017Landowski LM, ''Debunking neuromyths', Afternoons with Helen Shield', ABC Hobart 936AM, 28 February, 2017 (2017) [Media Interview]

[eCite] [Details]

2017Landowski LM, 'The gluten-free diet conundrum', Drive with Louise Saunders, ABC radio, 19 April, 2017 (2017) [Media Interview]

[eCite] [Details]

2017Landowski LM, 'International Pint of Science festival, and Dealing with the Degenerating brain', Drive with Louise Saunders, ABC936, 15 May (2017) [Media Interview]

[eCite] [Details]

2017Landowski LM, ''Modern Life, Modern Science': Evenings with Firas Massouh on ABC radio', ABC Radio 936, 28 June 2017 (2017) [Media Interview]

[eCite] [Details]

2017Landowski LM, 'Science can be beautiful, but please don't call it basic', The Conversation, online, 19 June 2017 (2017) [Magazine Article]

[eCite] [Details]

Tweet

2017Landowski L, 'Ryk Goddard of ABC breakfast radio interviews CEO of the Royal Hobart Hospital Research Foundation Heather Francis, and the 2017 Project grant recipient Dr Lila Landowski', ABC Radio936 (2017) [Media Interview]

[eCite] [Details]

2017Landowski LM, 'Science Club' science segment: Discussing anti-inflammatories as a treatment for depression, dog MRI's and whether our canine friends experience human emotions, health risks of e-cigarettes', Evenings with Melanie Tait on 936 ABC Hobart, 13 September 2017 (2017) [Media Interview]

[eCite] [Details]

2017Landowski LM, 'The effect of the holiday season on the brain: Impact of family, love, stress, binge-eating and alcohol', Breakfast with Ryk Goddard, ABC radio Hobart, 29 December 2017 (2017) [Media Interview]

[eCite] [Details]

2017Landowski LM, 'Science Club' Science Segment (Discussing breakthrough discoveries in Neanderthal research, brain maps, stroke therapies and funnel web spider venom)', Evenings with Melanie Tait, 936 ABC Hobart, 22 March, 2017 (2017) [Media Interview]

[eCite] [Details]

2017Landowski LM, Chapman JA, ''Science Club' Science Segment (Discussing breakthrough discoveries in artificial wombs, 3D printed ovaries and a quick way to diagnose depression)', Evenings with Melanie Tait, 936 ABC Hobart, 17 May (2017) [Media Interview]

[eCite] [Details]

Co-authors: Chapman JA

2017Landowski LM, Chapman JA, ''Science Club' Science Segment (Discussing the identification of control of baldness and grey hair, attracting female cane toads with the right call, better brain health in the sexually active elderly and understanding dementia', Evenings with Melanie Tait, 936 ABC, Hobart, Tasmania, 19 July (2017) [Media Interview]

[eCite] [Details]

Co-authors: Chapman JA

2017Landowski LM, Kean ZN, Chapman JA, 'ABC Hobart 936AM Interview: Science Club Panel Discussion (Discussing breakthrough discoveries in treating peanut allergies, origin of life and neurogenesis in the amygdala)', Evening with Melanie Tait ABC 936, 24 August 2017 (2017) [Media Interview]

[eCite] [Details]

Co-authors: Chapman JA

2017Landowski LM, Palfreyman JL, Chapman JA, ''Science Club' Science Segment (Discussing the best of 2017 in Science)', Evenings with Melanie Tait on 936 ABC Hobart, 7 December 2017 (2017) [Media Interview]

[eCite] [Details]

Co-authors: Palfreyman JL; Chapman JA

2017Landowski LM, Palfreyman JL, Chapman JA, 'The Year In Science. (Science Discussion Panel)', ABC Nightlife with Helen Shield National Broadcast, 22 December 2017 (2017) [Media Interview]

[eCite] [Details]

Co-authors: Palfreyman JL; Chapman JA

2017Landowski LM, Sutherland BA, Eaton E, 'Science in the Pub, Brain edition: Neuropathy, Stroke and Alzheimer's Disease', Afternoons with Helen Shield, ABC Hobart radio, 5 July 2017 (2017) [Media Interview]

[eCite] [Details]

Co-authors: Sutherland BA; Eaton E

2017Landowski LM, Venn A, Fitzgerald LM, 'WORK IT: Gender equality under the microscope', LOIS magazine, Tasmania, Winter 2017, 3, p. 20. (2017) [Magazine Article]

[eCite] [Details]

Co-authors: Venn A; Fitzgerald LM

2017Landowski LM, 'The neuroscience of addiction: focus of gambling addiction', Breakfast with Ryk Goddard, ABC936, 21 August 2017 (2017) [Media Interview]

[eCite] [Details]

2016Landowski LM, 'Achievers charge back into spotlight', The Mercury, The Mercury (2016) [Media Interview]

[eCite] [Details]

2016Landowski LM, 'State Finalist Young Australian of the Year 2016', The Mercury, October 16, 2015, p. 18. (2016) [Award]

[eCite] [Details]

2016Landowski LM, 'Science Club', 936 ABC Hobart, Tasmania (2016) [Media Interview]

[eCite] [Details]

2016Landowski LM, 'National Science Week segment on Melanie Tait's ABC statewide evening program. Discussing: The brain's waste removal system ('glymphatic system'), the possible looming cavendish banana extinction, 400-year old greenland sharks', Evenings with Melanie Tait on 936 ABC Hobart, 17 August, 2016 (2016) [Media Interview]

[eCite] [Details]

2016Landowski LM, ''Science Club' science segment', Evenings with Melanie Tait on 936 ABC Hobart, 6 July, 2016 (2016) [Media Interview]

[eCite] [Details]

2016Landowski LM, ''Science Club' science segment: Dementia - new treatments on the horizon?', Evenings with Melanie Tait on 936 ABC Hobart, 6 July, 2016 (2016) [Media Interview]

[eCite] [Details]

2016Landowski LM, 'Science club science panel: The effects of alcohol exposure during adolescence on stress responses and the brain during adulthood', Evenings with Melanie Tait on 936 ABC Hobart, 26 May, 2016 (2016) [Media Interview]

[eCite] [Details]

2016Landowski LM, 'Science club science panel (various topics)', Evenings with Melanie Tait on 936 ABC Hobart, 27 April, 2016 (2016) [Media Interview]

[eCite] [Details]

2016Landowski LM, 'Interviewing Dr Lila Landowski about science research, brains, and what life has had in store since winning the 2015 award for Young Achiever of the Year', Evenings with Firas Massouh on 936 ABC Hobart, 12 April, 2016 (2016) [Media Interview]

[eCite] [Details]

2016Landowski LM, ''Science Club' Science Segment (Discussing breakthrough discoveries in Aboriginal genetics and evolution, limbic system and mood, quantum computers)', Evenings with Melanie Tait, 936 ABC Hobart, 28 September, Hobart, Tasmania (2016) [Media Interview]

[eCite] [Details]

2016Landowski LM, 'Science Club' Science Segment (Discussing breakthrough discoveries in the genetics of obesity, male contraceptives and shipwrecks in the Black Sea)', Evenings with Melanie Tait, 936 ABC Hobart, Hobart, Australia, 26 October (2016) [Media Interview]

[eCite] [Details]

2016Landowski LM, 'What is dementia, and what hope is there for the future?', ABC radio (National program), Hobart, Australia, 3 October (2016) [Media Interview]

[eCite] [Details]

2016Landowski LM, 'Discussing the potential impact of the USA election outcomes on the future of world scientific research', Evenings with Melanie Tait, 936 ABC Hobart, November 10, 2016 (2016) [Media Interview]

[eCite] [Details]

2016Landowski LM, 'The effect of Christmas on the brain', ABC National Mornings, Hobart, Tasmania, 24 December (2016) [Media Interview]

[eCite] [Details]

2016Landowski LM, 'Science Club - Science Segment', Evenings with Melanie Tait, 936 ABC Hobart, Hobart, Tasmania, 7 December (2016) [Media Interview]

[eCite] [Details]

2015Landowski LM, 'Readers to discuss education challenges in the Hothouse', The Mercury, Tasmania, May 15, 2015 (2015) [Newspaper Article]

[eCite] [Details]

2015Landowski LM, 'Young achiever hits the right nerve', Hobart Ovserver, May 2015, p. 3. (2015) [Newspaper Article]

[eCite] [Details]

2015Landowski LM, 'Love that learning: Education need not be about getting a job', The Mercury, Hobart, Australia, June 12, 2015, p. 7. (2015) [Newspaper Article]

[eCite] [Details]

2015Landowski LM, 'Mentor role hothoused', The Mercury, Tasmania, June 4, 2015 (2015) [Newspaper Article]

[eCite] [Details]

2015Landowski LM, 'Hothouse: So no one will be left out in the cold', The Mercury, Tasmania, May 30, 2015 (2015) [Newspaper Article]

[eCite] [Details]

2015Landowski LM, 'Tasmanian Young Achiever of the Year: making waves in neuroscience', Aphra Magazine, online, May 17, 2015 (2015) [Newspaper Article]

[eCite] [Details]

2015Landowski LM, 'Hothouse submission', The Mercury, Online, May 13, 2015 (2015) [Newspaper Article]

[eCite] [Details]

2015Landowski LM, 'Australiansuper career kick start award' (2015) [Award]

[eCite] [Details]

2015Landowski LM, 'Winner, Premier's Young Achiever of the Year, Young Achiever Awards' (2015) [Award]

[eCite] [Details]

2015Landowski LM, 'Winner, St Luke's Health & Wellbeing Award, Young Achiever Awards' (2015) [Award]

[eCite] [Details]

2014Landowski LM, '2014 AUSTRALIANSUPER CAREER KICK START AWARD, Young Achiever Awards' (2014) [Award]

[eCite] [Details]

Grants & Funding

Funding Summary

Number of grants

3

Total funding

$564,183

Projects

Blood-brain barrier energy dysfunction: the unifying cause of fatigue (2017)$99,874
Description
Fatigue can be much more than just a sense of tiredness. It is also a debilitating symptom of many diseases and disorders, hampering peoples ability to perform the simplest of daily activities. The underlying mechanism of fatigue is unknown. We hypothesise that fatigue is ultimately the result of reduced delivery of energy to the brain. We will assess how energy supply is altered in fatigued brain. A special diet (that supplies an alternative energy source for the brain) will be used to circumvent this energy deficit. We hope to establish how fatigue occurs and offer clues to a simple treatment strategy.
Funding
The Mason Foundation ($99,874)
Scheme
Grant-Judith Jane Mason & Harold Stannett Williams
Administered By
University of Tasmania
Research Team
Howells DW; Sutherland BA; Landowski LM; Eaton ED; Allan S; Morten K
Year
2017
Paving the way for future stroke drug development: creating a reproducible, humanised model of stroke (2017 - 2019)$442,570
Description
Stroke is a leading cause of death and chronic disability. Stroke therapeutics developed in animal models fail when translated into human clinical trials, due to flaws inherent in these models. We will break through this translational roadblock by using magnetic microparticles to induce an ischemic stroke that accurately represents human disease
Funding
Royal Hobart Hospital Research Foundation ($442,570)
Scheme
Grant - Project Grant Funding
Administered By
University of Tasmania
Research Team
Landowski LM; Howells DW; Castley H; Sutherland BA; Kirkcaldie MTK
Period
2017 - 2019
Development of a therapeutic agent for a chemotherapy-induced neuropathy (2015)$21,739
Description
Chemotherapy-induced neuropathy (CIN) is a dose-limiting side effect of chemotherapy treatment, causing irreversible disability in 40% of cancer survivors. CIN results from the loss or damage of neurons during chemotherapy. We have compelling evidence that the protein metallothionein promotes regeneration of peripheral nerves, and examine its therapeutic use in CIN.This project will create new knowledge in the area of chemotherapy induced neuropathy, and establish the suitability of trophic agents as disease-modifying agents for chemotherapy-induced neuropathy.
Funding
Royal Hobart Hospital Research Foundation ($21,739)
Scheme
Grant-Clinical Research
Administered By
University of Tasmania
Research Team
Taylor BVM; Landowski LM; West AK; Vickers JC; Foa LC; Guven N
Year
2015

Research Supervision

  • 2015 - 1x Honours student (BMedRes)
  • 2017 – 4x Honours students (2x BMedRes, 2x MBBS)

Current

2

Current

DegreeTitleCommenced
PhDSurgical and Anaesthetic Comorbidity in Animal Models of Stroke: A veil over effective drug development2017
PhDPericyte Dysfunction Limiting Energy Supply in Alzheimer's Disease2018