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Ling Chen

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Ling Chen

Postdoctoral Research Fellow

Room 414-12 (Level 4), Medical Science 1, Hobart CBD Campuses

+61 3 6223 4238 (phone)

L.Chen@utas.edu.au

Dr Ling Chen is a Postdoctoral Research Fellow at the School of Medicine in the faculty of healthy. She is interested in the field of respiratory health and lung diseases.

Career summary

Qualifications

  • PhD, Chongqing University, China, 2014. The Effects of Cigarette Smoke Extract and Transforming Growth Factor- β1 on Human Airway Smooth Muscle Cells from Chronic Obstructive Pulmonary Disease
  • Masters, Chengdu Sports University, China, 2010. The Study of β2-adrenergic Receptor Gene Polymorphism in Sanda Athletes

Languages (other than English)

  • Mandarin; Chongqing dialect

Biography

Dr Chen has a PhD in Biomedical Engineering from Chongqing University, China (2014) and a master in Sport Physiology from Chengdu Sports University, China (2010). Before joining the university of Tasmania as a Postdoctoral Research Fellow in June 2014, Dr Chen had two years PhD research training at Woolcock Institute of Medical Research, Sydney (2011-2013).

Research Themes

Dr Chen's research aligns to the University's research theme of Better Health. Her research interests include investigating the pathophysiology of respiratory diseases and therapeutical approaches, and environmental effects on lung health.

View more on Dr Ling Chen in WARP

Expertise

  • Human lung tissue dissection and cell culture
  • Animal model and lung mechanics
  • Lung histology and stereology

Current projects

  • 'Effect of vitamin D on inflammatory responses in chronic obstructive pulmonary disease' - UTAS-REGS, 2015

Fields of Research

  • Respiratory Diseases (110203)
  • Ecosystem Function (050102)

Research Objectives

  • Respiratory System and Diseases (incl. Asthma) (920115)
  • Environmental Health (920405)

Publications

Total publications

20

Journal Article

(9 outputs)
YearCitationAltmetrics
2017Chen L, Eapen MS, Zosky GR, 'Vitamin D both facilitates and attenuates the cellular response to lipopolysaccharide', Scientific reports, 7 Article 45172. ISSN 2045-2322 (2017) [Refereed Article]

DOI: 10.1038/srep45172 [eCite] [Details]

Co-authors: Eapen MS; Zosky GR

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2017Chen L, Zosky G, 'Lung development', Photochemical & Photobiological Sciences, (3) pp. 339-346. ISSN 1474-9092 (2017) [Refereed Article]

DOI: 10.1039/C6PP00278A [eCite] [Details]

Co-authors: Zosky G

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2017Williams LJ, Chen L, Zosky GR, 'The respiratory health effects of geogenic (earth derived) PM10', Inhalation Toxicology, 29, (8) pp. 342-355. ISSN 0895-8378 (2017) [Refereed Article]

DOI: 10.1080/08958378.2017.1367054 [eCite] [Details]

Co-authors: Zosky GR

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2016Chen L, Wilson RR, Bennett Ellen, Zosky GR, 'Identification of vitamin D sensitive pathways during lung development', Respiratory Research, 17 pp. 1-11. ISSN 1465-993X (2016) [Refereed Article]

DOI: 10.1186/s12931-016-0362-3 [eCite] [Details]

Citations: Scopus - 2Web of Science - 3

Co-authors: Wilson RR; Bennett Ellen; Zosky GR

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2015Ge Q, Chen L, Jaffar J, Argaves WS, Twal WO, et al., 'Fibulin1C peptide induces cell attachment and extracellular matrix deposition in lung fibroblasts', Scientific Reports, 5 Article 9496. ISSN 2045-2322 (2015) [Refereed Article]

DOI: 10.1038/srep09496 [eCite] [Details]

Citations: Scopus - 4Web of Science - 5

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2014Chen L, Ge Q, Tjin G, Alkhouri H, Deng L, et al., 'Effects of cigarette smoke extract on human airway smooth muscle cells in COPD', The European Respiratory Journal, 44, (3) pp. 634-646. ISSN 0903-1936 (2014) [Refereed Article]

DOI: 10.1183/09031936.00171313 [eCite] [Details]

Citations: Scopus - 5Web of Science - 5

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2014Chen L, Perks KL, Stick SM, Kicic A, Larcombe AN, et al., 'House dust mite induced lung inflammation does not alter circulating vitamin D levels', PLoS One, 9, (11) Article e112589. ISSN 1932-6203 (2014) [Refereed Article]

DOI: 10.1371/journal.pone.0112589 [eCite] [Details]

Citations: Scopus - 3Web of Science - 2

Co-authors: Zosky G

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2014Ojo O, Lagan AL, Rajendran V, Spanjer A, Chen L, et al., 'Pathological changes in the COPD lung mesenchyme - Novel lessons learned from in vitro and in vivo studies', Pulmonary Pharmacology and Therapeutics, 29, (2) pp. 121-128. ISSN 1094-5539 (2014) [Refereed Article]

DOI: 10.1016/j.pupt.2014.04.004 [eCite] [Details]

Citations: Scopus - 15Web of Science - 13

Co-authors: Sohal SS

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2013Chen L, Black JL, Deng L, Burgess JK, Oliver BGG, 'Differential regulation of extracellular matrix and soluble fibulin-1 Levels by TGF-b1 in airway smooth muscle cells', PLoS One, 8, (6) Article e65544. ISSN 1932-6203 (2013) [Refereed Article]

DOI: 10.1371/journal.pone.0065544 [eCite] [Details]

Citations: Scopus - 10Web of Science - 7

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Conference Publication

(11 outputs)
YearCitationAltmetrics
2017Chen L, Bennett E, Wheeler A, Johnston F, Zosky G, 'Effect Of In Utero Exposure To Ceiling Particles On Post-Natal Lung Function And Immune Cell Populations', C105. Disorders of respiratory physiology and sleep in children, pp. A6889-A6889. (2017) [Conference Extract]

[eCite] [Details]

Co-authors: Bennett E; Wheeler A; Johnston F; Zosky G

2017Chen L, Bennett E, Wheeler A, Johnston F, Zosky G, 'Effect of In Utero Exposure to Ceiling Particles on Post-Natal Lung Function and Immune Cell Populations', Respirology, pp. 60, Vol 22. (2017) [Conference Extract]

[eCite] [Details]

Co-authors: Bennett E; Wheeler A; Johnston F; Zosky G

2017Chen L, Bennett E, Wheeler A, Johnston F, Zosky G, 'Effect Of In Utero Exposure To Ceiling Particles on the Early Post-Natal Immune Cell Populations', Respirology (2017) [Conference Extract]

[eCite] [Details]

Co-authors: Bennett E; Wheeler A; Johnston F; Zosky G

2015Chen L, Foong R, Bennett Ellen, Zosky GR, 'In utero vitamin D deficiency alters the expression of MMPs in foetal lung', Respirology, 27-29 March, 2015, Gold Coast, Australia, pp. 140. ISSN 1323-7799 (2015) [Conference Extract]

DOI: 10.1111/resp.12495 [eCite] [Details]

Co-authors: Bennett Ellen; Zosky GR

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2014Ge Q, Chen L, Jaffar J, Burgess JK, Oliver BG, 'The Role Of Fibulin-1C Peptides In Attachment, Proliferation And ECM Deposition In Lung Fibroblasts From Chronic Lung Diseases', American Journal of Respiratory and Critical Care Medicine, May 16-21, 2014, San Diego, pp. 1. ISSN 1073-449X (2014) [Conference Extract]

DOI: 10.1164/ajrccm-conference.2014.189.1 [eCite] [Details]

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2013Chen L, Ge Q, Black JL, Burgess JK, Oliver BG, 'Difference Between Matrix And Soluble Fibulin-1 In Airway Smooth Muscle Cells', American Journal of Respiratory and Critical Care Medicine, May 17-22, 2013, Philadelphia Pennsylvania, pp. A5632-A5632. ISSN 1073-449X (2013) [Conference Extract]

[eCite] [Details]

2013Chen L, Ge Q, Black JL, Burgess JK, Oliver BGG, 'Differences between deposited and soluble fibulin-1 in airway smooth muscle cells', Respirology, 23-27 March, 2013, Darwin, Australia, pp. 47. ISSN 1323-7799 (2013) [Conference Extract]

[eCite] [Details]

2013Chen L, Ge Q, Burgess J, Oliver B, 'Cigarette smoke extract and TGF-β1 induce distinctive expression of extracellular matrix protein genes in human airway smooth muscle cells', The European Respiratory Journal, 7-11 September 2013, Barcelona, pp. 1. ISSN 0903-1936 (2013) [Conference Extract]

[eCite] [Details]

2013Chen L, Ge Q, Faiz A, Black JL, Burgess JK, et al., 'Cigarette Smoke Extract And Tgf-β1 Induce Distinctive Expression Of Extracellular Matrix And Adhesion Molecule Genes In COPD And Non-COPD Airway Smooth Muscle Cells', American Journal of Respiratory and Critical Care Medicine, May 17-22, 2013, Philadelphia Pennsylvania ISSN 1073-449X (2013) [Conference Extract]

[eCite] [Details]

2013Ge Q, Jaffar J, Chen L, Black JL, Burgess JK, et al., 'Identification Of The Active Region Of Fibulin1 In Remodelling And Inflammation In Lung Fibroblasts', American Journal of Respiratory and Critical Care Medicine, May 17-22, 2013, Philadelphia Pennsylvania, pp. 1. ISSN 1073-449X (2013) [Conference Extract]

[eCite] [Details]

2012Ge Q, Krimmer D, Chen L, Burgess J, Black J, et al., 'Cigarette smoke induces a distinct fibrotic signature in bronchial epithelial cells in comparison to TGFß', American Journal of Respiratory and Critical Care Medicine, May 18-23, 2012, San Francisco, California, pp. 4584. ISSN 0903-1936 (2012) [Conference Extract]

[eCite] [Details]

Grants & Funding

Funding Summary

Number of grants

2

Total funding

$18,500

Projects

Annual Scientific Meeting of the Thoracic Society of Australia & New Zealand, Australia 27 March to 1 April 2015 (2015)$1,500
Funding
University of Tasmania ($1,500)
Scheme
Grant-Conference Support Scheme
Administered By
University of Tasmania
Research Team
Chen L
Year
2015
Effects of vitamin D on inflammatory responses in chronic obstructive pulmonary disease (2015)$17,000
Funding
University of Tasmania ($17,000)
Scheme
Grant-Research Enhancement (REGS)
Administered By
University of Tasmania
Research Team
Chen L
Year
2015