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Stephen Richards

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Stephen Richards

Stephen Richards

Senior Lecturer

Room 414-12 (Level 4), Medical Science 1, Hobart CBD Campuses

+61 3 6226 2673 (phone)

Stephen.Richards@utas.edu.au

Biography

Following a PhD under Emeritus Prof Mike Clark at the University of Tasmania, Dr Richards did post-doctoral research at the Baker Institute in Melbourne on cardioprotection (with Frank Rosenfeldt and Bob Conyers) and calcium signalling (with Alex Bobik and Craig Neylon) in normal and failing hearts.

Following two years at an INSERM unit in Montpellier, France, looking at intracellular Ca and pH signalling in normal and failing hearts with Michel Pucéat, he returned to the University of Melbourne to work briefly with Lea Delbridge on cardiac Ca signalling, supported by an NHMRC Howard Florey Centenary Fellowship.

In mid 1999, Dr Richards took up an academic appointment with the School of Medicine at UTAS, and resumed PhD work on muscle metabolism with Profs Mike Clark (Emeritus) and Steve Rattigan. In 2006 his lab joined the novated Menzies Institute for Medical Research under the Directorship of Prof Simon Foote.

Administrative expertise

  • Honours and Graduate Research Coordination
  • Senior Management Team, Menzies Institute for Medical Research
  • Deputy Chair Animal Ethics Committee

Teaching

Teaching responsibility

Dr Richards teaches extensively in undergraduate Biochemistry units, coordinating a number of second year units. He also has overall responsibility for coordinating the Honours programs offered by Medicine, including students doing research projects with the Menzies, and serve as Graduate Coordinator for Medicine, and as one of two GRC's for the Menzies Research Institute

Research Invitations

  • Co-organiser and chair of the Freycinet Symposium on 'Impact of muscle blood flow on diabetes and exercise' Tasmania, 2004
  • Invited speaker and chair of symposium on microbubbles at The 5th International Workshop on Drug Delivery Systems in the Czech Republic in May 15-18, 2007
  • Invited speaker, Heart Foundation Research Centre, School of Medical Science, Griffith Institute of Health and Medical Research, May 15, 2008
  • Invited speaker and organiser of symposium on microbubbles at The 6th International Workshop on Drug Delivery Systems in the Czech Republic in October 3-6, 2008

View more on Dr Stephen Richards in WARP

Research Themes

Dr Richards' Group has provided considerable evidence that the metabolism of muscle is heavily influenced by the supply of blood to the myocytes via the microvasculature, not only during exercise, but also upon exposure to insulin following a meal, when the muscle must rapidly store dietary glucose as muscle glycogen.

The Group has also found that the actions of insulin on microvascular blood flow are impaired or absent in obese, or insulin resistant humans and animals. Their three chief aims are:

  1. To understand the precise mechanism by which microvascular flow is altered to enhance delivery of nutrients and hormones (such as insulin itself) to muscle cells;
  2. To determine the biochemical nature and causes of impairment of microvascular blood flow regulation by insulin in pathological states such as insulin resistance;
  3. To discover alternative means of enhancing microvascular blood flow to overcome the impairment associated with insulin resistance.

The Group has developed a range of techniques for measuring microvascular blood flow in muscle, and couples these with techniques for assessing muscle metabolism in animal models of obesity, insulin resistance, diabetes and exercise training. Recent projects have focussed on:

  • the vascular and metabolic actions of the adipocyte-derived hormone adiponectin;
  • enhancement of the vascular and metabolic actions of insulin by agents that augment nitric oxide signalling, and AMPK signalling;
  • the role of the CNS in insulin action in the microvasculature;
  • analysis of the contribution of vasomotion to enhanced microvascular delivery by insulin.

Awards

  • NH&MRC Howard Florey Centenary Fellowship (1999)
  • Simone and Cino Del Duca Foundation Research Fellowship (1998)
  • American Heart Association Young Investigator Award (1996)

Fields of Research

  • Endocrinology (110306)
  • Systems Physiology (111603)
  • Cardiology (incl. Cardiovascular Diseases) (110201)
  • Epidemiology (111706)
  • Gene and Molecular Therapy (100401)
  • Agricultural Biotechnology Diagnostics (incl. Biosensors) (100101)
  • Animal Physiology - Systems (060603)
  • Cell Metabolism (060104)
  • Peripheral Nervous System (110905)
  • Basic Pharmacology (111501)
  • Public Health and Health Services (111799)
  • Medical Biochemistry: Carbohydrates (110102)
  • Aboriginal and Torres Strait Islander Health (111701)
  • Receptors and Membrane Biology (060110)
  • Animal Physiology - Cell (060602)
  • Physiology (060699)
  • Protein Trafficking (060108)
  • Public Nutrition Intervention (111104)
  • Medical Biochemistry: Nucleic Acids (110105)
  • Medical Biotechnology (100499)
  • Sensory Systems (110906)

Research Objectives

  • Diabetes (920104)
  • Cardiovascular System and Diseases (920103)
  • Human Diagnostics (860802)
  • Human Pharmaceutical Treatments (e.g. Antibiotics) (860803)
  • Disease Distribution and Transmission (incl. Surveillance and Response) (920404)
  • Neurodegenerative Disorders Related to Ageing (920112)
  • Digestive System Disorders (920105)
  • Expanding Knowledge in the Medical and Health Sciences (970111)
  • Clinical Health (Organs, Diseases and Abnormal Conditions) (920199)
  • Specific Population Health (excl. Indigenous Health) (920599)
  • Endocrine Organs and Diseases (excl. Diabetes) (920106)
  • Expanding Knowledge in the Environmental Sciences (970105)
  • Nervous System and Disorders (920111)
  • Cancer and Related Disorders (920102)
  • Nutrition (920411)
  • Skeletal System and Disorders (incl. Arthritis) (920116)

Publications

Total publications

68

Highlighted publications

(9 outputs)
YearTypeCitationAltmetrics
2011Journal ArticleBussey CT, Kolka CM, Rattigan S, Richards SM, 'Adiponectin opposes endothelin-1-mediated vasoconstriction in the perfused rat hindlimb', American Journal of Physiology: Heart and Circulatory Physiology, 301, (1) pp. H79-H86. ISSN 0363-6135 (2011) [Refereed Article]

DOI: 10.1152/ajpheart.00864.2010 [eCite] [Details]

Citations: Scopus - 19Web of Science - 21

Co-authors: Bussey CT; Kolka CM; Rattigan S

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2011Journal ArticleGenders AJ, Bradley EA, Rattigan S, Richards SM, 'cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle', American Journal of Physiology: Endocrinology and Metabolism, 301, (2) pp. E342-E350. ISSN 0193-1849 (2011) [Refereed Article]

DOI: 10.1152/ajpendo.00691.2010 [eCite] [Details]

Citations: Scopus - 9Web of Science - 9

Co-authors: Genders AJ; Bradley EA; Rattigan S

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2007Journal ArticleRattigan S, Bussey CT, Ross RM, Richards SM, 'Obesity, Insulin Resistance, and Capillary Recruitment', Microcirculation, 14, (4-5) pp. 299-309. ISSN 1073-9688 (2007) [Refereed Article]

DOI: 10.1080/10739680701282796 [eCite] [Details]

Citations: Scopus - 24Web of Science - 21

Co-authors: Rattigan S; Bussey CT; Ross RM

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2006Conference PublicationGenders AJ, Rattigan S, Clark MG, Richards SM, 'cGMP degrading phosphodiesterases are expressed differentially in skeletal muscle vasculature', Diabetes, vol 55, Supplement 1, 9-13 June, 2006, Washington, pp. A333. ISSN 0012-1797 (2006) [Conference Extract]

[eCite] [Details]

Co-authors: Genders AJ; Rattigan S; Clark MG

2006Journal ArticleMahajan H, Kolka CM, Newman JMB, Rattigan S, Richards SM, et al., 'Vascular and metabolic effects of methacholine in relation to insulin action in muscle', Diabetologia, 49, (4) pp. 713-723. ISSN 0012-186X (2006) [Refereed Article]

DOI: 10.1007/s00125-005-0110-6 [eCite] [Details]

Citations: Scopus - 4Web of Science - 3

Co-authors: Mahajan H; Kolka CM; Newman JMB; Rattigan S; Clark MG

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2006Journal ArticleRattigan S, Zhang L, Mahajan H, Kolka CM, Richards SM, et al., 'Factors influencing the hemodynamic and metabolic effects of insulin in muscle', Current Diabetes Reviews, 2, (1) pp. 61-70. ISSN 1573-3998 (2006) [Refereed Article]

DOI: 10.2174/157339906775473653 [eCite] [Details]

Citations: Scopus - 8

Co-authors: Rattigan S; Zhang L; Mahajan H; Kolka CM; Clark MG

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2004Journal ArticleMahajan H, Richards SM, Rattigan S, Clark MG, 'Local methacholine but not bradykinin potentiates insulin-mediated capillary recruitment and glucose uptake in muscle in vivo', Diabetologia, 47, (12) pp. 2226-2234. ISSN 0012-186X (2004) [Refereed Article]

DOI: 10.1007/s00125-004-1580-7 [eCite] [Details]

Citations: Scopus - 18Web of Science - 15

Co-authors: Mahajan H; Rattigan S; Clark MG

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2003Journal ArticleMahajan H, Richards SM, Rattigan S, Clark MG, 'T-1032, a cyclic GMP phosphodiesterase-5 inhibitor, acutely blocks physiologic insulin-mediated muscle haemodynamic effects and glucose uptake in vivo', British Journal of Pharmacology, 140, (7) pp. 1283-1291. ISSN 0007-1188 (2003) [Refereed Article]

DOI: 10.1038/sj.bjp.0705548 [eCite] [Details]

Citations: Scopus - 8Web of Science - 7

Co-authors: Mahajan H; Rattigan S; Clark MG

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2003Conference PublicationRichards SM, Wheatley CM, Zhang L, Rattigan S, Barrett EJ, et al., 'Contraction-mediated muscle capillary recruitment and metabolic responses in vivo are resistant to TNFα', Diabetologia, Vol 46, Supplement 2, 24-29 August, 2003, Paris, pp. A58. ISSN 0012-186X (2003) [Conference Extract]

[eCite] [Details]

Co-authors: Zhang L; Rattigan S; Clark MG

Journal Article

(43 outputs)
YearCitationAltmetrics
2018Hu D, Remash D, Russell RD, Greenaway T, Rattigan S, et al., 'Impairments in adipose tissue microcirculation in Type 2 diabetes mellitus assessed by real-time contrast-enhanced ultrasound', Circulation: Cardiovascular Imaging, 11, (4) Article e007074. ISSN 1942-0080 (2018) [Refereed Article]

DOI: 10.1161/CIRCIMAGING.117.007074 [eCite] [Details]

Citations: Scopus - 2Web of Science - 2

Co-authors: Remash D; Russell RD; Greenaway T; Rattigan S; Squibb KA; Jones G; Premilovac D; Keske MA

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2018Hu D, Russell RD, Remash D, Greenaway T, Rattigan S, et al., 'Are the metabolic benefits of resistance training in type 2 diabetes linked to improvements in adipose tissue microvascular blood flow?', American Journal of Physiology: Endocrinology and Metabolism, 315, (6) pp. E1242-E1250. ISSN 0193-1849 (2018) [Refereed Article]

DOI: 10.1152/ajpendo.00234.2018 [eCite] [Details]

Co-authors: Russell RD; Remash D; Greenaway T; Rattigan S; Squibb KA; Jones G; Ross RM; Premilovac D; Keske MA

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2018Russell RD, Hu D, Greenaway T, Sharman JE, Rattigan S, et al., 'Oral glucose challenge impairs skeletal muscle microvascular blood flow in healthy people', American Journal of Physiology - Endocrinology and Metabolism, 315, (2) pp. E307-E315. ISSN 0193-1849 (2018) [Refereed Article]

DOI: 10.1152/ajpendo.00448.2017 [eCite] [Details]

Co-authors: Russell RD; Greenaway T; Sharman JE; Rattigan S; Keske MA

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2018Premilovac D, Attrill E, Rattigan S, Richards SM, Kim J, et al., 'Acute, local infusion of angiotensin II impairs microvascular and metabolic insulin sensitivity in skeletal muscle', Cardiovascular Research pp. 1-12. ISSN 0008-6363 (2018) [Refereed Article]

DOI: 10.1093/cvr/cvy225 [eCite] [Details]

Citations: Scopus - 1Web of Science - 4

Co-authors: Premilovac D; Rattigan S; Keske MA

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2017Keske MA, Dwyer RM, Russell RD, Blackwood SJ, Brown AA, et al., 'Regulation of microvascular flow and metabolism: An overview', Clinical and Experimental Pharmacology and Physiology, 44, (1) pp. 143-149. ISSN 0305-1870 (2017) [Refereed Article]

DOI: 10.1111/1440-1681.12688 [eCite] [Details]

Citations: Scopus - 5Web of Science - 6

Co-authors: Keske MA; Dwyer RM; Russell RD; Blackwood SJ; Brown AA; Premilovac D; Rattigan S

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2017Russell RD, Hu D, Greenaway T, Blackwood SJ, Dwyer RM, et al., 'Skeletal muscle microvascular-linked improvements in glycemic control from resistance training in individuals with Type 2 Diabetes', Diabetes Care, 40, (9) pp. 1256-1263. ISSN 0149-5992 (2017) [Refereed Article]

DOI: 10.2337/dc16-2750 [eCite] [Details]

Citations: Scopus - 7Web of Science - 5

Co-authors: Russell RD; Greenaway T; Blackwood SJ; Dwyer RM; Sharman JE; Jones G; Squibb KA; Brown AA; Otahal P; Al-Aubaidy H; Premilovac D; Hitchins S; Rattigan S; Keske MA

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2017Blackwood SJ, Dwyer RM, Bradley EA, Keske MA, Richards SM, et al., 'Determination of skeletal muscle microvascular flowmotion with contrast-enhanced ultrasound', Ultrasound in Medicine and Biology, 43, (9) pp. 2013-2023. ISSN 0301-5629 (2017) [Refereed Article]

DOI: 10.1016/j.ultrasmedbio.2017.05.012 [eCite] [Details]

Co-authors: Blackwood SJ; Dwyer RM; Bradley EA; Keske MA; Rattigan S

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2017Ng HLH, Premilovac D, Rattigan S, Richards SM, Muniyappa R, et al., 'Acute vascular and metabolic actions of the green tea polyphenol epigallocatechin 3-gallate in rat skeletal muscle', Journal of Nutritional Biochemistry, 40 pp. 23-31. ISSN 0955-2863 (2017) [Refereed Article]

DOI: 10.1016/j.jnutbio.2016.10.005 [eCite] [Details]

Citations: Scopus - 2Web of Science - 2

Co-authors: Ng HLH; Premilovac D; Rattigan S; Keske MA

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2016Keske MA, Premilovac D, Bradley EA, Dwyer RM, Richards SM, et al., 'Muscle microvascular blood flow responses in insulin resistance and ageing', The Journal of Physiology, 594, (8) pp. 2223-2231. ISSN 1469-7793 (2016) [Refereed Article]

DOI: 10.1113/jphysiol.2014.283549 [eCite] [Details]

Citations: Scopus - 18Web of Science - 21

Co-authors: Keske MA; Premilovac D; Bradley EA; Dwyer RM; Rattigan S

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2015Bradley EA, Zhang L, Genders AJ, Richards SM, Rattigan S, et al., 'Enhancement of insulin-mediated rat muscle glucose uptake and microvascular perfusion by 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside', Cardiovascular Diabetology, 14, (1) Article 91. ISSN 1475-2840 (2015) [Refereed Article]

DOI: 10.1186/s12933-015-0251-y [eCite] [Details]

Citations: Scopus - 3Web of Science - 3

Co-authors: Bradley EA; Rattigan S; Keske MA

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2014Premilovac D, Richards SM, Rattigan S, Keske MA, 'A vascular mechanism for high-sodium-induced insulin resistance in rats', Diabetologia: Clinical and Experimental Diabetes and Metabolism, 57, (12) pp. 2586-2595. ISSN 0012-186X (2014) [Refereed Article]

DOI: 10.1007/s00125-014-3373-y [eCite] [Details]

Citations: Scopus - 11Web of Science - 10

Co-authors: Premilovac D; Rattigan S; Keske MA

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2013Premilovac D, Bradley EA, Ng HLH, Richards SM, Rattigan S, et al., 'Muscle insulin resistance resulting from impaired microvascular insulin sensitivity in Sprague Dawley rats', Cardiovascular Research, 98, (1) pp. 28-36. ISSN 0008-6363 (2013) [Refereed Article]

DOI: 10.1093/cvr/cvt015 [eCite] [Details]

Citations: Scopus - 20Web of Science - 17

Co-authors: Premilovac D; Bradley EA; Ng HLH; Rattigan S; Keske MA

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2013Bradley EA, Richards SM, Keske MA, Rattigan S, 'Local NOS inhibition impairs vascular and metabolic actions of insulin in rat hindleg muscle in vivo', American Journal of Physiology: Endocrinology and Metabolism, 305, (6) pp. E745-E750. ISSN 0193-1849 (2013) [Refereed Article]

DOI: 10.1152/ajpendo.00289.2013 [eCite] [Details]

Citations: Scopus - 18Web of Science - 18

Co-authors: Bradley EA; Keske MA; Rattigan S

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2013Rattigan S, Richards SM, Keske MA, 'Microvascular contributions to insulin resistance', Diabetes, 62, (2) pp. 343-345. ISSN 0012-1797 (2013) [Contribution to Refereed Journal]

DOI: 10.2337/db12-1193 [eCite] [Details]

Citations: Scopus - 9Web of Science - 10

Co-authors: Rattigan S; Keske MA

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2013Premilovac D, Roberts-Thompson KM, Ng HLH, Bradley EA, Richards SM, et al., 'Blueberry tea enhances insulin sensitivity by augmenting insulin-mediated metabolic and microvascular responses in skeletal muscle of high fat fed rats', International Journal of Diabetology & Vascular Disease Research, 1, (8) pp. 1-10. ISSN 2328-353X (2013) [Non Refereed Article]

[eCite] [Details]

Co-authors: Premilovac D; Ng HLH; Bradley EA; Rattigan S; Keske MA

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2012St-Pierre P, Keith LJ, Richards SM, Rattigan S, Keske MA, 'Microvascular blood flow responses to muscle contraction are not altered by high-fat feeding in rats', Diabetes, Obesity and Metabolism, 14, (8) pp. 753-761. ISSN 1462-8902 (2012) [Refereed Article]

DOI: 10.1111/j.1463-1326.2012.01598.x [eCite] [Details]

Citations: Scopus - 8Web of Science - 9

Co-authors: Keith LJ; Rattigan S; Keske MA

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2011Bussey CT, Kolka CM, Rattigan S, Richards SM, 'Adiponectin opposes endothelin-1-mediated vasoconstriction in the perfused rat hindlimb', American Journal of Physiology: Heart and Circulatory Physiology, 301, (1) pp. H79-H86. ISSN 0363-6135 (2011) [Refereed Article]

DOI: 10.1152/ajpheart.00864.2010 [eCite] [Details]

Citations: Scopus - 19Web of Science - 21

Co-authors: Bussey CT; Kolka CM; Rattigan S

Tweet

2011Genders AJ, Bradley EA, Rattigan S, Richards SM, 'cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle', American Journal of Physiology: Endocrinology and Metabolism, 301, (2) pp. E342-E350. ISSN 0193-1849 (2011) [Refereed Article]

DOI: 10.1152/ajpendo.00691.2010 [eCite] [Details]

Citations: Scopus - 9Web of Science - 9

Co-authors: Genders AJ; Bradley EA; Rattigan S

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2010St Pierre P, Genders AJ, Keske MA, Richards SM, Rattigan S, 'Loss of insulin-mediated microvascular perfusion in skeletal muscle is associated with the development of insulin resistance ', Diabetes Obesity & Metabolism, 12, (9) pp. 798-805. ISSN 1462-8902 (2010) [Refereed Article]

DOI: 10.1111/j.1463-1326.2010.01235.x [eCite] [Details]

Citations: Scopus - 25Web of Science - 24

Co-authors: Genders AJ; Keske MA; Rattigan S

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2009McLean SR, Richards SM, Cover S, Brandon S, Davies NW, et al., 'Papyriferic Acid, an antifeedant triterpene from birch trees, inhibits succinate dehydrogenase from liver mitochondria', Journal of Chemical Ecology, 35, (10) pp. 1252-1261. ISSN 0098-0331 (2009) [Refereed Article]

DOI: 10.1007/s10886-009-9702-9 [eCite] [Details]

Citations: Scopus - 13Web of Science - 9

Co-authors: McLean SR; Cover S; Brandon S; Davies NW

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2009Newman JMB, Dwyer RM, St Pierre P, Richards SM, Clark MG, et al., 'Decreased microvascular vasomotion and myogenic response in rat skeletal muscle in association with acute insulin resistance', Journal of Physiology, 587, (11) pp. 2579-2588. ISSN 0022-3751 (2009) [Refereed Article]

DOI: 10.1113/jphysiol.2009.169011 [eCite] [Details]

Citations: Scopus - 45Web of Science - 42

Co-authors: Newman JMB; Dwyer RM; Clark MG; Rattigan S

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2008Dwyer T, Blizzard L, Patterson B, Ponsonby A-L, Martin K, et al., 'Association between birth weight and adolescent systolic blood pressure in a caucasian birth cohort differs according to skin type, CRH promoter or 11β-HSD2 genotype', Archives of Disease in Childhood, 93, (9) pp. 760-767. ISSN 0003-9888 (2008) [Refereed Article]

DOI: 10.1136/adc.2007.129122 [eCite] [Details]

Citations: Scopus - 3Web of Science - 3

Co-authors: Dwyer T; Blizzard L; Patterson B; Ponsonby A-L; Martin K; Quinn S; Sale MM; Dickinson JL

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2008Ponsonby AL, Blizzard CL, Pezic A, Cochrane JA, Ellis JA, et al., 'Adiposity Gain During Childhood, ACE I/D Polymorphisms and Metabolic Outcomes', Obesity, 16, (9) pp. 2141-2147. ISSN 1930-7381 (2008) [Refereed Article]

DOI: 10.1038/oby.2008.302 [eCite] [Details]

Citations: Scopus - 12Web of Science - 11

Co-authors: Ponsonby AL; Blizzard CL; Cochrane JA; Dickinson JL; Sale MM; Dwyer T

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2008Ross RM, Downey KA, Newman JMB, Richards SM, Clark MG, et al., 'Contrast-enhanced ultrasound measurement of microvascular perfusion relevant to nutrient and hormone delivery in skeletal muscle: A model study in vitro', Microvascular Research, 75, (3) pp. 323-329. ISSN 0026-2862 (2008) [Refereed Article]

DOI: 10.1016/j.mvr.2007.11.002 [eCite] [Details]

Citations: Scopus - 8Web of Science - 8

Co-authors: Ross RM; Downey KA; Newman JMB; Clark MG; Rattigan S

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2007Kolka CM, Rattigan S, Richards SM, Clark MG, 'Potential for endothelin-1-mediated impairment of contractile activity in hypertension', Clinical and Experimental Physiology and Pharmacology, 34, (3) pp. 217-222. ISSN 0305-1870 (2007) [Refereed Article]

DOI: 10.1111/j.1440-1681.2007.04575.x [eCite] [Details]

Citations: Scopus - 1Web of Science - 5

Co-authors: Kolka CM; Rattigan S; Clark MG

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2007Rattigan S, Bussey CT, Ross RM, Richards SM, 'Obesity, Insulin Resistance, and Capillary Recruitment', Microcirculation, 14, (4-5) pp. 299-309. ISSN 1073-9688 (2007) [Refereed Article]

DOI: 10.1080/10739680701282796 [eCite] [Details]

Citations: Scopus - 24Web of Science - 21

Co-authors: Rattigan S; Bussey CT; Ross RM

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2007Vollus GC, Bradley EA, Roberts NK, Newman JMB, Richards SM, et al., 'Graded occlusion of perfused rat muscle vasculature decreases insulin action', Clinical Science, 112, (8) pp. 457-466. ISSN 0143-5221 (2007) [Refereed Article]

DOI: 10.1042/CS20060311 [eCite] [Details]

Citations: Scopus - 14Web of Science - 11

Co-authors: Vollus GC; Bradley EA; Roberts NK; Newman JMB; Rattigan S; Clark MG

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2007Newman JMB, Ross RM, Richards SM, Clark MG, Rattigan S, 'Insulin and contraction increase nutritive blood flow in rat muscle in vivo: determined by microdialysis of L-[14C]glucose', Journal of Physiology, 585, (1) pp. 217-229. ISSN 0022-3751 (2007) [Refereed Article]

DOI: 10.1113/jphysiol.2007.138818 [eCite] [Details]

Citations: Scopus - 14Web of Science - 13

Co-authors: Newman JMB; Ross RM; Clark MG; Rattigan S

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2006Mahajan H, Kolka CM, Newman JMB, Rattigan S, Richards SM, et al., 'Vascular and metabolic effects of methacholine in relation to insulin action in muscle', Diabetologia, 49, (4) pp. 713-723. ISSN 0012-186X (2006) [Refereed Article]

DOI: 10.1007/s00125-005-0110-6 [eCite] [Details]

Citations: Scopus - 4Web of Science - 3

Co-authors: Mahajan H; Kolka CM; Newman JMB; Rattigan S; Clark MG

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2006Rattigan S, Bradley EA, Richards SM, Clark MG, 'Muscle metabolism and control of capillary blood flow: insulin and exercise', Essays in Biochemistry, 42, (1) pp. 133-144. ISSN 0071-1365 (2006) [Refereed Article]

DOI: 10.1042/bse0420133 [eCite] [Details]

Citations: Scopus - 7Web of Science - 6

Co-authors: Rattigan S; Bradley EA; Clark MG

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2006Rattigan S, Zhang L, Mahajan H, Kolka CM, Richards SM, et al., 'Factors influencing the hemodynamic and metabolic effects of insulin in muscle', Current Diabetes Reviews, 2, (1) pp. 61-70. ISSN 1573-3998 (2006) [Refereed Article]

DOI: 10.2174/157339906775473653 [eCite] [Details]

Citations: Scopus - 8

Co-authors: Rattigan S; Zhang L; Mahajan H; Kolka CM; Clark MG

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2005Domenighetti AA, Wang Q, Egger M, Richards SM, Pedrazzini T, et al., 'Angiotensin II-mediated phenotypic cardiomyocyte remodeling leads to age-dependent cardiac dysfunction and failure', Hypertension, 46, (2) pp. 426-432. ISSN 0194-911X (2005) [Refereed Article]

DOI: 10.1161/01.HYP.0000173069.53699.d9 [eCite] [Details]

Citations: Scopus - 74Web of Science - 68

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2005Kolka CM, Rattigan S, Richards SM, Barrett EJ EJ, Clark MG, 'Endothelial Na+ -D-glucose cotransporter: No Role in Insulin-mediated Glucose Uptake ', Hormone and Metabolic Research, 37, (11) pp. 657-661. ISSN 0018-5043 (2005) [Refereed Article]

DOI: 10.1055/s-2005-870574 [eCite] [Details]

Citations: Scopus - 2Web of Science - 2

Co-authors: Kolka CM; Rattigan S; Clark MG

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2005Kolka CM, Rattigan S, Richards SM, Clark MG, 'Metabolic and vascular actions of endothelin-1 are inhibited by insulin-mediated vasodilation in perfused rat hindlimb muscle', British Journal of Pharmacology, 145, (7) pp. 992-1000. ISSN 0007-1188 (2005) [Refereed Article]

DOI: 10.1038/sj.bjp.0706263 [eCite] [Details]

Citations: Scopus - 14Web of Science - 15

Co-authors: Kolka CM; Rattigan S; Clark MG

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2005Rattigan S, Wheatley C, Richards SM, Barrett EJ, Clark MG, 'Exercise and insulin-mediated capillary recruitment in muscle', Exercise and Sport Sciences Reviews, 33, (1) pp. 43-48. ISSN 0091-6331 (2005) [Refereed Article]

PMID: 15640720 [eCite] [Details]

Citations: Scopus - 22Web of Science - 26

Co-authors: Rattigan S

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2005Wallis MG, Smith ME, Kolka CM, Zhang L, Richards SM, et al., 'Acute glucosamine-induced insulin resistance in muscle in vivo is associated with impaired capillary recruitment', Diabetologia, 48, (10) pp. 2131-2139. ISSN 0012-186X (2005) [Refereed Article]

DOI: 10.1007/s00125-005-1887-z [eCite] [Details]

Citations: Scopus - 26Web of Science - 22

Co-authors: Smith ME; Kolka CM; Zhang L; Rattigan S; Clark MG

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2005Zhang L, Newman JMB, Richards SM, Rattigan S, Clark MG, 'Microvascular flow routes in muscle controlled by vasoconstrictors', Microvascular Research, 70, (1) pp. 7-16. ISSN 0026-2862 (2005) [Refereed Article]

DOI: 10.1016/j.mvr.2005.06.001 [eCite] [Details]

Citations: Scopus - 13Web of Science - 11

Co-authors: Zhang L; Newman JMB; Rattigan S; Clark MG

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2004Mahajan H, Richards SM, Rattigan S, Clark MG, 'Local methacholine but not bradykinin potentiates insulin-mediated capillary recruitment and glucose uptake in muscle in vivo', Diabetologia, 47, (12) pp. 2226-2234. ISSN 0012-186X (2004) [Refereed Article]

DOI: 10.1007/s00125-004-1580-7 [eCite] [Details]

Citations: Scopus - 18Web of Science - 15

Co-authors: Mahajan H; Rattigan S; Clark MG

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2004Wheatley CM, Rattigan S, Richards SM, Barrett EJ, Clark MG, 'Skeletal muscle contraction stimulates capillary recruitment and glucose uptake in insulin resistant obese Zucker rats', American Journal of Physiology - Endocrinology and Metabolism, 287, (4) pp. E804-E807. ISSN 0193-1849 (2004) [Refereed Article]

DOI: 10.1152/ajpendo.00077.2004 [eCite] [Details]

Citations: Scopus - 43Web of Science - 45

Co-authors: Rattigan S; Clark MG

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2004Zhang L, Vincent MA, Richards SM, Clerk LH, Rattigan S, et al., 'Insulin sensitivity of muscle capillary recruitment in vivo', Diabetes, 53, (2) pp. 447-453. ISSN 0012-1797 (2004) [Refereed Article]

DOI: 10.2337/diabetes.53.2.447 [eCite] [Details]

Citations: Scopus - 124Web of Science - 116

Co-authors: Zhang L; Vincent MA; Rattigan S; Clark MG

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2003Clark MG, Wallis MG, Barrett EJ, Vincent MA, Richards SM, et al., 'Blood flow and muscle metabolism: a focus on insulin action', American Journal of Physiology: Endocrinology and Metabolism, 284, (2) pp. E241-E258. ISSN 0193-1849 (2003) [Refereed Article]

DOI: 10.1152/ajpendo.00408.2002 [eCite] [Details]

Citations: Web of Science - 206

Co-authors: Clark MG; Vincent MA; Rattigan S

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2003Mahajan H, Richards SM, Rattigan S, Clark MG, 'T-1032, a cyclic GMP phosphodiesterase-5 inhibitor, acutely blocks physiologic insulin-mediated muscle haemodynamic effects and glucose uptake in vivo', British Journal of Pharmacology, 140, (7) pp. 1283-1291. ISSN 0007-1188 (2003) [Refereed Article]

DOI: 10.1038/sj.bjp.0705548 [eCite] [Details]

Citations: Scopus - 8Web of Science - 7

Co-authors: Mahajan H; Rattigan S; Clark MG

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2003Zhang L, Wheatley CM, Richards SM, Barrett EJ, Clark MG, et al., 'TNFalpha acutely inhibits vascular effects of physiological but not high insulin or contraction', American Journal of Physiology: Endocrinology and Metabolism, 285, (3 ) pp. E654-E660. ISSN 0193-1849 (2003) [Refereed Article]

DOI: 10.1152/ajpendo.00119.2003 [eCite] [Details]

Citations: Scopus - 44Web of Science - 44

Co-authors: Zhang L; Clark MG; Rattigan S

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Chapter in Book

(1 outputs)
YearCitationAltmetrics
2013Premilovac D, Ng HLH, Richards SM, Bradley EA, Dwyer RM, et al., 'Role for the Microvasculature in Glucose Uptake in Skeletal Muscle', Glucose Uptake: Regulation, Signaling Pathways and Health Implications (Endocrinology Research and Clinical Developments), Nova Science Publishers, Johnson CC and Williams DB (ed), New York, pp. 109-139. ISBN 978-1-62618-670-5 (2013) [Research Book Chapter]

[eCite] [Details]

Co-authors: Premilovac D; Ng HLH; Bradley EA; Dwyer RM; Rattigan S; Keske MA

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Conference Publication

(24 outputs)
YearCitationAltmetrics
2016Hu Donghua, Russell RD, Sharman JE, Rattigan S, Jacobson GA, et al., 'Effect of blueberry tea on improving metabolic and vascular function in people with and without type 2 diabetes - A Pilot Study', Australian Diabetes Society and Australian Diabetes Educators Association Annual Scientific Meeting 2016, 24-26 August, 2016, Gold Coast, Australia (2016) [Conference Extract]

[eCite] [Details]

Co-authors: Russell RD; Sharman JE; Rattigan S; Jacobson GA; Al-Aubaidy HAM; Keske MAV

2011Newman JMB, Dwyer RM, Keske MAV, Richards SM, Rattigan S, 'Flow motion in skeletal muscle is associated with increased nutritive flow and insulin action', Proceedings of the 71st Scientific Sessions of the American Diabetes Association, 24-28 June, San Diego, California, pp. 1740-P. (2011) [Conference Extract]

[eCite] [Details]

Co-authors: Newman JMB; Dwyer RM; Keske MAV; Rattigan S

2006Dwyer RM, Newman JMB, Richards SM, Rattigan S, Clark MG, 'Laser Doppler flowmetry, but not contrast enhanced ultrasound, influenced by flow when measuring changes in muscle capillary recruitment - a study in vitro', Proceedings of Meeting, 13th September, 2006, Copenhagen, pp. 16. (2006) [Conference Extract]

[eCite] [Details]

Co-authors: Dwyer RM; Newman JMB; Rattigan S; Clark MG

2006Genders AJ, Rattigan S, Clark MG, Richards SM, 'cGMP degrading phosphodiesterases are expressed differentially in skeletal muscle vasculature', Diabetes, vol 55, Supplement 1, 9-13 June, 2006, Washington, pp. A333. ISSN 0012-1797 (2006) [Conference Extract]

[eCite] [Details]

Co-authors: Genders AJ; Rattigan S; Clark MG

2006Genders AJ, Rattigan S, Clark MG, Richards SM, 'Differential expression of cGMP degrading phosphodiesterases in skeletal muscle vasculature', Proceedings, 24-28 September, 2006, Brisbane, pp. 130. ISSN 1328-4924 (2006) [Conference Extract]

[eCite] [Details]

Co-authors: Genders AJ; Rattigan S; Clark MG

2006Newman JMB, Clark MG, Dwyer RM, Richards SM, Rattigan S, 'Use of microdialysis to assess capillary recruitment in muscle - a study in vitro', Proceedings of Meeting, 13th September, 2006, Copenhagen, pp. 17. (2006) [Conference Extract]

[eCite] [Details]

Co-authors: Newman JMB; Clark MG; Dwyer RM; Rattigan S

2006Clark MG, Dwyer RM, Newman JMB, Richards SM, Rattigan S, 'A comparison of ultrasound and laser Doppler for Measuring Capillary Recruitment Using Models in vitro', Proceedings, 27-30 September, 2006, Indianapolis, pp. 10. (2006) [Conference Extract]

[eCite] [Details]

Co-authors: Clark MG; Dwyer RM; Newman JMB; Rattigan S

2005Kolka CM, Rattigan S, Richards SM, Clark MG, 'Endothelin-1 vascular and resultant metabolic actions in perfused rat hindlimb are opposed by insulin', Diabetologia, vol 48, Supplement 1, 10-15 September, 2005, Athens, pp. A230. ISSN 0012-186X (2005) [Conference Extract]

[eCite] [Details]

Co-authors: Kolka CM; Rattigan S; Clark MG

2005Mahajan H, Richards SM, Rattigan S, Clark MG, 'Local infusion of an inhibitor of Ca2+ dependent K+ channels (TEA), but not L-NAME blocks insulin-mediated capillary recruitment and glucose uptake in muscle in vivo', Diabetes, Vol 54, Supplement 1, June 10-14, 2005, San Diego, pp. A379. ISSN 0012-1797 (2005) [Conference Extract]

[eCite] [Details]

Co-authors: Mahajan H; Rattigan S; Clark MG

2005Vollus GC, Newman JMB, Richards SM, Barrett EJ, Rattigan S, 'Partial microsphere embolism of muscle leads to acute impairment of insulin-mediated glucose uptake without compromising resting energetics', Diabetes, Vol 54, Supplement 1, June 10-14, 2005, San Diego, pp. A379. ISSN 0012-1797 (2005) [Conference Extract]

[eCite] [Details]

Co-authors: Vollus GC; Newman JMB; Rattigan S

2005Wheatley CM, O'Farrell GM, Richards SM, Smith S, Clark MG, 'Rosiglitazone partly reverses insulin resistance in the obese Zucker rat but fails to recover insulin-mediated capillary recruitment and glucose uptake in muscle', Diabetes, Vol 54, Supplement 1, June 10-14, 2005, San Diego, pp. A642. ISSN 0012-1797 (2005) [Conference Extract]

[eCite] [Details]

Co-authors: O'Farrell GM; Clark MG

2005Clark MG, Wallis MG, Smith ME, Kolka CM, Zhang L, et al., 'Glucosamine induces acute insulin resistance in muscle in vivo assocaited with impaired capillary recruitment', Diabetologia, 48 (S1), 10-15 September, 2005, Athens, pp. A210. ISSN 0012-186X (2005) [Conference Extract]

[eCite] [Details]

Co-authors: Clark MG; Smith ME; Kolka CM; Zhang L; Rattigan S

2004Kolka CM, Rattigan S, Richards SM, Clark MG, 'Endothelin-1 as a messenger for insulin has both stimulatory and inhibitory effects on perfused muscle metabolism via its vascular actions', Diabetes, Vol 53, Supplement 2, June 4-8, 2004, Orlando, pp. A368. ISSN 0012-1797 (2004) [Conference Extract]

[eCite] [Details]

Co-authors: Kolka CM; Rattigan S; Clark MG

2004Mahajan H, Richards SM, Rattigan S, Clark MG, 'Local methacholine but not bradykinin potentiates insulin-mediated capillary recruitment and glucose uptake in muscle in vivo', Diabetes, Vol 53, Supplement 2, June 4-8, 2004, Orlando, pp. A369. ISSN 0012-1797 (2004) [Conference Extract]

[eCite] [Details]

Co-authors: Mahajan H; Rattigan S; Clark MG

2004Steinberg GR, Dwyer RM, Carey AL, Rogers S, Richards SM, et al., 'Interleukin-6 increases glucose uptake but does not increase AMPK activity in L6 myotubes and perfused rat hindlimb', Proceedings of AMPK Meeting, 23-26 March, 2004, Lorne, pp. 126. (2004) [Conference Extract]

[eCite] [Details]

Co-authors: Dwyer RM; Rattigan S; Clark MG

2004Wheatley CM, Barrett EJ, Bradley EA, Richards SM, Clark MG, et al., 'Muscle capillary recruitment and glucose uptake of genetically obese rats respond to contractions but not insulin', Diabetes, Vol 53, Supplement 2, June 4-8, 2004, Orlando, pp. A371. ISSN 0012-1797 (2004) [Conference Extract]

[eCite] [Details]

Co-authors: Bradley EA; Clark MG; Rattigan S

2004Wheatley CM, Richards SM, Clark MG, Barrett EJ, Rattigan S, 'Role of capillary recruitment in the potentiation of insulin action by prior exercise', Diabetes, Vol 53, Supplement 2, June 4-8, 2004, Orlando, pp. A28. ISSN 0012-1797 (2004) [Conference Extract]

[eCite] [Details]

Co-authors: Clark MG; Rattigan S

2003Bradley EA, Zhang L, Newman JMB, Richards SM, Clark MG, et al., 'Acute divergent effects of AICAR on insulin action in vivo', Diabetes, Vol 52, Supplement 1, June 13-17, 2003, New Orleans, pp. A344. ISSN 0012-1797 (2003) [Conference Extract]

[eCite] [Details]

Co-authors: Bradley EA; Zhang L; Newman JMB; Clark MG; Rattigan S

2003Mahajan H, Richards SM, Rattigan S, Clark MG, 'T-1032 a cyclic GMP phosphodiesterase-5 inhibitor blocks physiologic insulin-mediated muscle hemodynamic effects and glucose uptake in vivo', Diabetes, Vol 52, Supplement 1, June 13-17, 2003, New Orleans, pp. A541. ISSN 0012-1797 (2003) [Conference Extract]

[eCite] [Details]

Co-authors: Mahajan H; Rattigan S; Clark MG

2003Richards SM, Wheatley CM, Zhang L, Rattigan S, Barrett EJ, et al., 'Contraction-mediated muscle capillary recruitment and metabolic responses in vivo are resistant to TNFα', Diabetologia, Vol 46, Supplement 2, 24-29 August, 2003, Paris, pp. A58. ISSN 0012-186X (2003) [Conference Extract]

[eCite] [Details]

Co-authors: Zhang L; Rattigan S; Clark MG

2003Zhang L, Richards SM, Rattigan S, Barrett EJ, Clark MG, 'Capillary recruitment in muscle is a highly sensitive event in insulin action in vivo', Diabetes, Vol 52, Supplement 1, June 13-17, 2003, New Orleans, pp. A48. ISSN 0012-1797 (2003) [Conference Extract]

[eCite] [Details]

Co-authors: Zhang L; Rattigan S; Clark MG

2002Wheatley CM, Bradley EA, Wallis MG, Rattigan S, Richards SM, et al., 'Contraction-mediated capillary recruitment is not impaired in muscle of insulin-resistant obese Zucker rats', Diabetes, Vol 51, Supplement 2, June 14-18, 2002, San Francisco, pp. A564. ISSN 0012-1797 (2002) [Conference Extract]

[eCite] [Details]

Co-authors: Bradley EA; Rattigan S; Clark MG

2002Zhang L, Rattigan S, Richards SM, Clark MG, 'TNF? inhibits low physiologic but not high insulin-mediated capillary recruitment and glucose uptake in vivo', Diabetes, Vol 51, Supplement 2, June 14-18, 2002, San Francisco, pp. A565. ISSN 0012-1797 (2002) [Conference Extract]

[eCite] [Details]

Co-authors: Zhang L; Rattigan S; Clark MG

2001Clark MG, Barrett EJ, Richards SM, Clark ADH, Rattigan S, 'Microvascular involvement in insulin resistance of skeletal muscle', Proceedings of the 7th World Congress for Microcirculation, August 19-22, 2001, Sydney, pp. 31-37. (2001) [Non Refereed Conference Paper]

[eCite] [Details]

Co-authors: Clark MG; Clark ADH; Rattigan S

Grants & Funding

Funding Summary

Number of grants

22

Total funding

$3,324,837

Projects

Role of microvascular flowmotion in skeletal muscle glucose metabolism (2013 - 2015)$576,533
Description
Obesity and type 2 diabetes are nationally and globally reaching epidemic rates. This project investigates the regulation of blood flow within muscle and its impact on metabolism. Outcomes from the study may lead to diagnostic tools and treatments for cardiovascular disease associated with obesity, hypertension and type 2 diabetes.
Funding
National Health & Medical Research Council ($576,533)
Scheme
Grant-Project
Administered By
University of Tasmania
Research Team
Rattigan S; Keske MAV; Richards SM; Ross RM
Period
2013 - 2015
Grant Reference
1043474_HF
Adipose tissue blood flow: the link between obesity and disease risk? (2012)$7,580
Funding
The Select Foundation ($7,580)
Scheme
Grant-Small Grants Scheme
Administered By
University of Tasmania
Research Team
Richards SM; Keske MAV
Year
2012
Microvascular Defects and Insulin Resistance (2011 - 2012)$127,490
Funding
National Heart Foundation ($127,490)
Scheme
Grant-In-Aid
Administered By
University of Tasmania
Research Team
Rattigan S; Keske MAV; Richards SM
Period
2011 - 2012
NHMRC Standard Equipment Grant - 2008 (2008)$72,611
Funding
National Health & Medical Research Council ($72,611)
Scheme
Grant-Equipment
Administered By
University of Tasmania
Research Team
Keske MAV; Rattigan S; Richards SM
Year
2008
Grant Reference
580023
Interaction between adiponectin and insulin in vascular control of glucose uptake in muscle (2008 - 2009)$119,574
Funding
National Heart Foundation ($119,574)
Scheme
Grant-In-Aid
Administered By
University of Tasmania
Research Team
Rattigan S; Richards SM
Period
2008 - 2009
Central and Peripheral Actions of Insulin for the Control of Muscle Capillary Recruitment (2007 - 2009)$417,750
Funding
National Health & Medical Research Council ($417,750)
Scheme
Grant-Project
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Richards SM; Choi-Lundberg DL
Period
2007 - 2009
Grant Reference
457603
Endothelin-1, type2 diabetes and hypertension (2007 - 2008)$112,680
Funding
National Heart Foundation ($112,680)
Scheme
Grant-In-Aid
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Richards SM; Kolka CM
Period
2007 - 2008
The Effects of Insulin on the Microvasculature (2006 - 2010)$347,499
Funding
National Institutes of Health ($347,499)
Scheme
Grant
Administered By
University of Virginia
Research Team
Clark MG; Rattigan S; Richards SM
Period
2006 - 2010
Isoelectric Focussing System (2006)$15,080
Funding
National Health & Medical Research Council ($15,080)
Scheme
Grant-Equipment
Administered By
University of Tasmania
Research Team
Richards SM; Rattigan S
Year
2006
Grant Reference
361670
Nutrient and Hormone Delivery to Muscle: Interactions between Insulin and Exercise (2005 - 2007)$299,500
Funding
National Health & Medical Research Council ($299,500)
Scheme
Grant-Project Three Year
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Richards SM
Period
2005 - 2007
Grant Reference
352600
Leica DMIRB Inverted Microscope Configured for Fluorescence and Bright Field with Phase Contrast (2005)$10,000
Funding
National Health & Medical Research Council ($10,000)
Scheme
Grant-Equipment
Administered By
University of Tasmania
Research Team
Chuah MI; West AK; Holloway AF; Rattigan S; Richards SM; Chung RS; Foa LC
Year
2005
Grant Reference
264668
Ultrasound in Muscle Vascular Research, Diagnosis and Gene Therapy (2004 - 2006)$285,000
Funding
Australian Research Council ($285,000)
Scheme
Grant-Discovery Projects
Administered By
University of Tasmania
Research Team
Clark MG; Richards SM
Period
2004 - 2006
Grant Reference
DP0449669
Muscle Vascular Research and Gene Therapy Using Ultrasound (2004)$142,900
Funding
Australian Research Council ($102,900)
Collaborators
Deakin University ($10,000); Royal Melbourne Institute of Technology University ($10,000); University of Melbourne ($10,000); University of New South Wales ($10,000)
Scheme
Grant-Linkage Infrastructure
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Richards SM
Year
2004
Grant Reference
LE0452281
Refrigerated Benchtop Centrifuge (2004)$12,941
Funding
National Health & Medical Research Council ($12,941)
Scheme
Grant-Equipment
Administered By
University of Tasmania
Research Team
Holloway AF; West AK; Chuah MI; Rattigan S; Richards SM
Year
2004
Grant Reference
264536
Gradient Thermal Cycler for PCR (2004)$7,055
Funding
National Health & Medical Research Council ($7,055)
Scheme
Grant-Equipment
Administered By
University of Tasmania
Research Team
Richards SM; Rattigan S
Year
2004
Grant Reference
264536
Augmenting Microvascular Blood Flow in Muscle (2003 - 2005)$210,000
Funding
National Health & Medical Research Council ($210,000)
Scheme
Grant-Project Three Year
Administered By
University of Tasmania
Research Team
Clark MG; Richards SM; Rattigan S
Period
2003 - 2005
Grant Reference
253900
Relationship Between Muscle Insulin Resistance and High Blood Pressure (2003 - 2004)$90,000
Funding
National Heart Foundation ($90,000)
Scheme
Grant-In-Aid
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Richards SM
Period
2003 - 2004
Genetic Factors that Predispose Low Birth Weight Babies to Increased Risk of Hypertension and IGT (2002 - 2003)$95,000
Funding
National Health & Medical Research Council ($95,000)
Scheme
Grant-Project Three Year
Administered By
University of Tasmania
Research Team
Dwyer T; Sale MM; Richards SM; Morley R; Rich Stephen; Blizzard CL
Period
2002 - 2003
Grant Reference
211309
A Novel Form of Resting Muscle Thermogenesis from Na+ Cycling Regulated by Signals from Blood Vessels (2001 - 2003)$201,530
Funding
Australian Research Council ($201,530)
Scheme
Grant-Large
Administered By
University of Tasmania
Research Team
Clark MG; Richards SM
Period
2001 - 2003
Grant Reference
A00105049
Detrimental Haemodynamic Changes in Skeletal Muscle From Chronic Heart Failure (2001 - 2002)$68,400
Funding
National Heart Foundation ($68,400)
Scheme
Grant-In-Aid
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Richards SM
Period
2001 - 2002
Development of Laser Doppler Flowmetry for Assessment of Muscle Microvascular Flow in Insulin Resistance (2000)$32,200
Funding
Clifford Craig Foundation ($32,200)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Richards SM; Clark ADH
Year
2000
The Role of Nutritive and Non-nutritive Blood Flow on Lipid Clearance by Normal and Insulin-resistant Muscle (1999 - 2000)$73,514
Funding
National Heart Foundation ($73,514)
Scheme
Grant-In-Aid
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Richards SM
Period
1999 - 2000

Research Supervision

During my career I have co-authored 92 meeting presentations and 58 peer-reviewed publications (12 since 2009), including Circulation [IF 14.43], PNAS [IF 9.77], Diabetes [IF 8.89], Hypertension [IF 6.91], and J Cell Sci [IF 6.29]. My work has been cited 1330 times, and I have an h-index of 20.

Current

2

Completed

15

Current

DegreeTitleCommenced
PhDThe Health Impacts of Hazelwood Coal Fire Particles2018
PhDResponsiveness of In Vitro and In Vivo Skeletal Muscle Pericytes to Circulating and Muscle-Derived Paracrine Vasoactive Molecules2018

Completed

DegreeTitleCompleted
PhDRole of Adipose Tissue Microvascular Blood Flow in Type 2 Diabetes
Candidate: Donghua Hu
2018
PhDInflammation is Not a Contributing Factor in the Development of Insulin Resistance in Diet Induced Obesity in Rats
Candidate: Aascha Adriana Brown
2017
PhDCharacterisation of Flowmotion in Healthy Controls and Type 2 Diabetes
Candidate: Sarah Joan Blackwood
2017
PhDEffect of the Green Tea Polyphenol, EGCG, on Insulin Sensitivity
Candidate: Huei Leng Helena Ng
2014
PhDMicrovascular Dysfunction and the Development of Muscle Insulin Resistance
Candidate: Dino Premilovac
2012
PhDHemodynamic and Metabolic Actions of Adiponectin in Muscle
Candidate: Carol Therese Bussey
2011
PhDRole of the Microvasculature in the Development of Muscle Insulin Resistance
Candidate: Philippe St-Pierre
2010
MastersVascular and Metabolic Actions of Insulin and AMPK Activation in Muscle
Candidate: Eloise Alice Bradley
2009
PhDEnhancing Blood Flow and Glucose Uptake in Insulin-Resistant Skeletal Muscle
Candidate: Amanda Joan Genders
2009
PhDExercise and Insulin: Muscle Haemodynamics and Metabolism
Candidate: Renee Dwyer
2007
PhDGlucose Uptake in Skeletal Muscle
Candidate: Cathryn Mary Kolka
2006
PhDInsulin-Mediated Capillary Recruitment: Regulatory and Anatomical Aspects
Candidate: Lei Zhang
2005
PhDHemodynamic and metabolic changes in muscle in relation to insulin action
Candidate: Hema Mahajan
2005
PhDNovel Technologies and Measurement of Microvascular Blood Flow in Muscle
Candidate: Andrew Douglas Hastings Clark
2005
PhDInteractions between contraction, insulin and thiazolidinediones in skeletal muscle; a focus on capillary recruitment
Candidate: Catherine Mary Wheatley
2004