Profiles

Joanne Dickinson

UTAS Home Assoc Prof Joanne Dickinson

Joanne Dickinson

Principal Research Fellow (ARC Future Fellow)
Menzies Institute for Medical Research

Hobart CBD Campuses

+61 3 6226 7622 (phone)

Jo.Dickinson@utas.edu.au

The vast majority of people's lives are affected by cancer.  Some people are more likely to develop cancer than others, with some developing more aggressive cancers and others milder forms of disease.  Also, some respond well to treatment and others don't.  Associate Professor of cancer genetics, Jo Dickinson, is trying to find out why.

Understanding the genetics that lead to cancer

The vast majority of people's lives are affected by cancer. Some people are more likely to develop cancer than others, with some developing more aggressive cancers and others milder forms of disease. Also, some respond well to treatment and others do not. Associate Professor of cancer genetics, Jo Dickinson, is trying to find out why.

'Genetics determines everything about you. What you look like, how your body works, your risk of disease, how you respond to infections, how you respond to chemicals, even your response to your environment, like sun,' said Associate Professor Dickinson.

'I want to understand the genetic factors that lead to certain cancers, why some people develop aggressive cancers and what determines our response to treatment.'

'If we know what genetic factors lead to a particular cancer, then we can test people for them. We can profile their risk, which could lead to earlier detection. We can target our treatments to more effectively treat cancers and hopefully stop the disease from being life threatening,' said Associate Professor Dickinson.

One such discovery made by Associate Professor Dickinson is the role of a sticky molecule, or protein, that sits on the surface of cells, and plays an important role in the spread of cells. This protein is now being investigated as a target for new cancer therapies.

'This was a significant discovery because if we can prevent cancer cells from spreading we could cure a lot of cancers.

'Currently, most cancers require severe treatments like chemotherapy or radiotherapy. Unfortunately these treatments can have many side effects because we don't know which are the best treatments to use for each type of cancer. Also, these treatments aren't effective for everyone and we don't know why.

'For example, radiotherapy is only effective in treating about half of the men diagnosed with prostate cancer, and we don't know which men will respond best to treatment. If we knew, we would only treat the men that radiotherapy is likely to be effective for. We need to find the genetic basis for people's response to therapy,' said Associate Professor Dickinson.

'To understand the genetic basis of disease, we need to conduct research in people affected with disease. One useful approach is to study families with multiple members affected by the same disease.'

Associate Professor Dickinson said that Tasmania is an ideal place to contribute to this globally significant issue due to its stable and isolated population.

'There is great scope to work with multiple generations of families, which is essential to understanding the genetic basis for cancer.'

'We have a great relationship with the community. People in Tasmania are happy to be involved because they are very supportive of the health research and the Menzies.

'Our biggest barrier currently is the shrinking amount of funding devoted to medical research. I believe there is a valuable opportunity for businesses to step in and become involved in promoting and supporting health research.

'Large dollars go into advertising and sponsorship which surrounds some of the more highly profitable professional sport and entertainment industries, but if businesses really want to leave a positive footprint in their communities, funding groundbreaking health research is another option with a lasting and positive impact.'

Dr Joanne Dickinson is a Associate Professor of cancer genetics at the Menzies Institute for Medical Research. She was a National Health and Medical Research Council (NHMRC) funded scholar for her PhD in pathology focusing on cancer research. Dr Dickinson's research interests are in understanding how inherited differences in genes contribute to the development of different types of cancers including blood and prostate cancer. She is also interested in how inherited differences in genes influence how disease progresses. Her important contributions over her career include one of the earliest reports of a new role for a group of proteins in cell death in cancer. Her important contributions to our understanding the genetic basis of disease has included inherited eye disease and most recently prostate cancer and tumour spread.

Career summary

Qualifications

  • PhD (Pathology), University of Queensland, Australia, 1996
  • BSc (Hons - Pathology), University of Queensland, Australia, 1996

Memberships

Other

Assoc Prof Dickinson is a current member of the National Breast Cancer Foundation Research Advisory Committee, and a NHMRC project grant panel member in 2011,2012 and 2013. She reviews for the ARC and Cancer Australia. She has acted as a grant reviewer for the Wellcome Trust, Medical Research Council (UK) and nationally she has reviewed annually for the NHMRC project grant scheme (since 2005), the NHMRC Centre for Clinical Research Excellence Scheme in 2010 and 2011, the Leukaemia Foundation and Diabetes Australia. Assoc Prof Dickinson reviews for a variety of journals including Molecular Cancer Therapeutics,PloS One, and Genes and Immunity. Assoc Prof is Deputy Chair of the Human Research Ethics Committee (Tasmania Network).

Teaching

Teaching expertise

Assoc Prof Dickinson's contributions to research training include supervision of PhD and Honours students.

View more on AssocProf Joanne Dickinson in WARP

Research Themes

Assoc Prof Dickinson's research aligns with one of the University's key research themes of Better Health. She leads one of the five research Themes (Cancer, Genetics and Immunology) at the University of Tasmania's Menzies Institute for Medical Research. Her administrative responsibilities includes management of four research groups within this theme. Assoc Prof Dickinson's primary research interest is in the discovery of genetic contributors to complex diseases, the focus being the genetic study of large families with multiple cases of disease ascertained from the Tasmanian population. The Tasmanian familial genetic resources now established have been recognized both nationally and internationally. Building the genetic research capabilities of the in-house genetics facility has been her primary focus over the past two years. She has built genetic analysis infrastructure generating hi-throughput genetic and epigenetic analysis capabilities, computing facilities capable of handling large volumes of data, in addition to attracting skilled bioinformatics and genetics expertise.

Fields of Research

  • Cancer Genetics (111203)
  • Medical Genetics (excl. Cancer Genetics) (110311)
  • Oncology and Carcinogenesis (111299)
  • Epidemiology (111706)
  • Epigenetics (incl. Genome Methylation and Epigenomics) (060404)
  • Ophthalmology (111301)
  • Haematology (110202)
  • Cancer Cell Biology (111201)
  • Gene Expression (incl. Microarray and other genome-wide approaches) (060405)
  • Molecular Targets (111207)
  • Genetics (060499)
  • Preventive Medicine (111716)
  • Population, Ecological and Evolutionary Genetics (060411)
  • Genomics (060408)
  • Marine and Estuarine Ecology (incl. Marine Ichthyology) (060205)
  • Bioethics (human and animal) (220101)
  • Solid Tumours (111209)
  • Biochemistry and Cell Biology (060199)
  • Neurology and Neuromuscular Diseases (110904)
  • Medical Biochemistry and Metabolomics (110199)
  • Cellular Immunology (110704)
  • Neurogenetics (060410)
  • Property Law (excl. Intellectual Property Law) (180124)
  • Public Health and Health Services (111799)
  • Clinical Chemistry (diagnostics) (110302)
  • Cancer Diagnosis (111202)
  • Immunological and Bioassay Methods (030104)
  • Immunology (110799)
  • Aboriginal and Torres Strait Islander Health (111701)
  • Paediatrics (111403)
  • Haematological Tumours (111206)
  • Probability Theory (010404)
  • Medical Biochemistry: Nucleic Acids (110105)
  • Law (180199)
  • Biodiscovery (100201)
  • Law and Society (180119)
  • Cancer Therapy (excl. Chemotherapy and Radiation Therapy) (111204)
  • Primary Health Care (111717)
  • Pathology (110316)
  • Rural Sociology (160804)
  • Health and Community Services (111708)
  • Respiratory Diseases (110203)
  • Anaesthesiology (110301)
  • Physiotherapy (110317)
  • Genome Structure and Regulation (060407)
  • Applied Ethics (220199)
  • Applied Statistics (010401)
  • Medical Biotechnology (100499)
  • Cell and Nuclear Division (060402)
  • Computer Software (080399)
  • Biocatalysis and Enzyme Technology (100301)
  • Geriatrics and Gerontology (110308)

Research Objectives

  • Cancer and Related Disorders (920102)
  • Inherited Diseases (incl. Gene Therapy) (920110)
  • Hearing, Vision, Speech and Their Disorders (920107)
  • Men's Health (920504)
  • Urogenital System and Disorders (920119)
  • Nervous System and Disorders (920111)
  • Expanding Knowledge in the Biological Sciences (970106)
  • Health (929999)
  • Preventive Medicine (920412)
  • Blood Disorders (920101)
  • Immune System and Allergy (920108)
  • Marine Flora, Fauna and Biodiversity (960808)
  • Expanding Knowledge in the Medical and Health Sciences (970111)
  • Bioethics (950401)
  • Disease Distribution and Transmission (incl. Surveillance and Response) (920404)
  • Clinical Health (Organs, Diseases and Abnormal Conditions) (920199)
  • Public Health (excl. Specific Population Health) (920499)
  • Aboriginal and Torres Strait Islander Health - Determinants of Health (920301)
  • Digestive System Disorders (920105)
  • Mental Health (920410)
  • Ecosystem Assessment and Management at Regional or Larger Scales (960501)
  • Human Diagnostics (860802)
  • Expanding Knowledge in Economics (970114)
  • Health Inequalities (920206)
  • Specific Population Health (excl. Indigenous Health) (920599)
  • Rural Health (920506)
  • Endocrine Organs and Diseases (excl. Diabetes) (920106)
  • Health Status (e.g. Indicators of Well-Being) (920408)
  • Skeletal System and Disorders (incl. Arthritis) (920116)
  • Respiratory System and Diseases (incl. Asthma) (920115)
  • Health Related to Ageing (920502)
  • Allied Health Therapies (excl. Mental Health Services) (920201)
  • Dental Health (920402)
  • Indigenous Health (920399)
  • Skin and Related Disorders (920117)
  • Child Health (920501)
  • Diagnostic Methods (920203)
  • Behaviour and Health (920401)
  • Expanding Knowledge in the Environmental Sciences (970105)
  • Application Software Packages (excl. Computer Games) (890201)

Publications

Total publications

94

Highlighted publications

(9 outputs)
YearTypeCitationAltmetrics
2011Journal ArticleKote-Jarai Z, Al Olama AA, Giles GG, Severi G, Schleutker J, et al., 'Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study', Nature Genetics, 43, (8) pp. 785-791. ISSN 1061-4036 (2011) [Refereed Article]

DOI: 10.1038/ng.882 [eCite] [Details]

Citations: Scopus - 176Web of Science - 165

Co-authors: Fitzgerald L; Marthick JR; Patterson B

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2011Journal ArticleTegg EM, Thomson RJ, Stankovich JM, Banks A, Marsden KA, et al., 'Anticipation in familial hematologic malignancies', Blood, 117, (4) pp. 1308-1310. ISSN 0006-4971 (2011) [Refereed Article]

DOI: 10.1182/blood-2010-07-296475 [eCite] [Details]

Citations: Scopus - 8Web of Science - 7

Co-authors: Tegg EM; Thomson RJ; Stankovich JM; Banks A; Marsden KA; Lowenthal RM; Foote SJ

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2009Journal ArticleEeles RA, Kote-Jarai Z, Amin Al Olama A, Giles GG, Guy M, et al., 'Identification of seven new prostate cancer susceptibility loci through a genome-wide association study', Nature Genetics, 41, (10) pp. 1116-1121. ISSN 1061-4036 (2009) [Refereed Article]

DOI: 10.1038/ng.450 [eCite] [Details]

Citations: Scopus - 302Web of Science - 284

Co-authors: Fitzgerald LM; Polanowski AM; Patterson B; The UK ProtecT Study The PRACTICAL Consortium

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2009Journal ArticleFitzgerald LM, Patterson B, Thomson RJ, Polanowski AM, Quinn SJ, et al., 'Identification of a prostate cancer susceptibility gene on chromosome 5p13q12 associated with risk of both familial and sporadic disease', European Journal of Human Genetics, 17 pp. 368-377. ISSN 1018-4813 (2009) [Refereed Article]

DOI: 10.1038/ejhg.2008.171 [eCite] [Details]

Citations: Scopus - 18Web of Science - 18

Co-authors: Fitzgerald LM; Patterson B; Thomson RJ; Polanowski AM; Quinn SJ; Mackey DA; Dwyer T; Foote SJ; Stankovich J; McKay JD

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2008Journal ArticleDwyer T, Van der Mei IAF, Ponsonby AL, Taylor BVM, Stankovich J, et al., 'Melanocortin 1 receptor genotype, past environmental sun exposure, and risk of multiple sclerosis', Neurology, 71, (8) pp. 583-589. ISSN 0028-3878 (2008) [Refereed Article]

DOI: 10.1212/01.wnl.0000323928.57408.93 [eCite] [Details]

Citations: Scopus - 31Web of Science - 32

Co-authors: Dwyer T; Van der Mei IAF; Ponsonby AL; Taylor BVM; Stankovich J; Thomson Russell; Polanowski AM

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1999Journal ArticleFingert JH, Heon E, Liebmann JM, Yamamoto T, Craig JE, et al., 'Analysis of myocilin mutations in 1703 glaucoma patients from five different populations', Human Molecular Genetics, 8, (5) pp. 899-905. ISSN 0964-6906 (1999) [Refereed Article]

DOI: 10.1093/hmg/8.5.899 [eCite] [Details]

Citations: Scopus - 424Web of Science - 381

Co-authors: Mackey DA

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1998Journal ArticleAntalis TM, Linn ML, Donnan K, Mateo L, Gardner J, et al., 'The serine proteinase inhibitor (Serpin) plasminogen activation inhibitor type 2 protects against viral cytopathic effects by constitutive interferon alpha/beta priming', Journal of Experimental Medicine, 187, (11) pp. 1799-1811. ISSN 0022-1007 (1998) [Refereed Article]

DOI: 10.1084/jem.187.11.1799 [eCite] [Details]

Citations: Scopus - 69Web of Science - 59

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1998Journal ArticleDickinson JL, Norris BJ, Jensen PH, Antalis TM, 'The C-D interhelical domain of the serpin plasminogen activator inhibitor-type 2 is required for protection from TNF- induced apoptosis', Cell Death and Differentiation, 5, (2) pp. 163-171. ISSN 1350-9047 (1998) [Refereed Article]

DOI: 10.1038/sj.cdd.4400324 [eCite] [Details]

Citations: Scopus - 64Web of Science - 55

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1995Journal ArticleDickinson JL, Bates EJ, Ferrante A, Antalis TM, 'Plasminogen activator inhibitor type 2 inhibits tumour necrosis factor alpha-induced apoptosis. Evidence for an alternate biological function', Journal of Biological Chemistry, 270, (46) pp. 27894-27904. ISSN 0021-9258 (1995) [Refereed Article]

DOI: 10.1074/jbc.270.46.27894 [eCite] [Details]

Citations: Scopus - 203Web of Science - 201

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Journal Article

(69 outputs)
YearCitationAltmetrics
2017Blackburn NB, Marthick JR, Banks A, Charlesworth JC, Marsden KA, et al., 'Evaluating a CLL susceptibility variant in ITGB2 in families with multiple sub-types of hematological malignancies', Blood, 130, (1) pp. 86-88. ISSN 0006-4971 (2017) [Refereed Article]

DOI: 10.1182/blood-2017-03-774232 [eCite] [Details]

Co-authors: Blackburn NB; Marthick JR; Banks A; Charlesworth JC; Lowenthal RM

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2017De Paoli-Iseppi R, Deagle BE, McMahon CR, Hindell MA, Dickinson JL, et al., 'Measuring animal age with DNA methylation: from humans to wild animals', Frontiers in Genetics, 8 Article 106. ISSN 1664-8021 (2017) [Refereed Article]

DOI: 10.3389/fgene.2017.00106 [eCite] [Details]

Citations: Scopus - 1Web of Science - 1

Co-authors: Deagle BE; Hindell MA

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2017Nicol D, McWhirter R, Dickinson J, 'Implementing values-based governance for a new bioresource model', Journal of Law and the Biosciences pp. 1-8. ISSN 2053-9711 (2017) [Refereed Article]

DOI: 10.1093/jlb/lsx007 [eCite] [Details]

Co-authors: Nicol D; McWhirter R

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2017Phillips JL, Taberlay PC, Woodworth AM, Hardy K, Brettingham-Moore KH, et al., 'Distinct mechanisms of regulation of the ITGA6 and ITGB4 genes by RUNX1 in myeloid cells', Journal of Cellular Physiology pp. 1-38. ISSN 0021-9541 (2017) [Refereed Article]

DOI: 10.1002/jcp.26197 [eCite] [Details]

Co-authors: Phillips JL; Taberlay PC; Woodworth AM; Brettingham-Moore KH; Holloway AF

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2017Nicol D, Eckstein L, Morrison M, Sherkow JS, Otlowski M, et al., 'Key challenges in bringing CRISPR-mediated somatic cell therapy into the clinic', Genome Medicine, 9 Article 85. ISSN 1756-994X (2017) [Refereed Article]

DOI: 10.1186/s13073-017-0475-4 [eCite] [Details]

Co-authors: Nicol D; Eckstein L; Otlowski M; Burdon KP; Chalmers D; Charlesworth J; Hewitt AW; Nielsen J; McWhirter RE

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2016Cazaly E, Thomson R, Marthick JR, Holloway AF, Charlesworth J, et al., 'Comparison of pre-processing methodologies for Illumina 450k methylation array data in familial analyses', Clinical Epigenetics, 8, (1) Article 75. ISSN 1868-7083 (2016) [Refereed Article]

DOI: 10.1186/s13148-016-0241-2 [eCite] [Details]

Co-authors: Cazaly E; Thomson R; Marthick JR; Holloway AF; Charlesworth J

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2016Atashrazm F, Lowenthal RM, Dickinson JL, Holloway AF, Woods GM, 'Fucoidan enhances the therapeutic potential of arsenic trioxide and all-trans retinoic acid in acute promyelocytic leukemia, in vitro and in vivo', OncoTarget, 7, (29) pp. 46028-46041. ISSN 1949-2553 (2016) [Refereed Article]

DOI: 10.18632/oncotarget.10016 [eCite] [Details]

Citations: Scopus - 4Web of Science - 3

Co-authors: Lowenthal RM; Holloway AF; Woods GM

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2016Nicol D, Bubela T, Chalmers D, Charbonneau J, Critchley C, et al., 'Precision medicine: drowning in a regulatory soup?', Journal of Law and the Biosciences, 3, (2) pp. 281-303. ISSN 2053-9711 (2016) [Refereed Article]

DOI: 10.1093/jlb/lsw018 [eCite] [Details]

Citations: Web of Science - 5

Co-authors: Nicol D; Chalmers D; Charbonneau J; Hewitt AW; McWhirter R; Otlowski M

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2015Amin Al Olama A, Benlloch S, Antoniou AC, Giles GG, Severi G, et al., 'Risk analysis of prostate cancer in PRACTICAL, a multinational consortium, using 25 known prostate cancer susceptibility loci', Cancer Epidemiology, Biomarkers and Prevention, 24, (7) pp. 1121-1129. ISSN 1055-9965 (2015) [Refereed Article]

DOI: 10.1158/1055-9965.EPI-14-0317 [eCite] [Details]

Citations: Scopus - 26Web of Science - 20

Co-authors: Fitzgerald L

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2015Atashrazm F, Lowenthal RM, Woods GM, Holloway AF, Dickinson JL, 'Fucoidan and cancer: a multifunctional molecule with anti-tumor potential', Marine Drugs, 13, (4) pp. 2327-2346. ISSN 1660-3397 (2015) [Refereed Article]

DOI: 10.3390/md13042327 [eCite] [Details]

Citations: Scopus - 35Web of Science - 35

Co-authors: Lowenthal RM; Woods GM; Holloway AF

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2015Atashrazm F, Lowenthal RM, Woods GM, Holloway AF, Karpiniec SS, et al., 'Fucoidan suppresses the growth of human acute promyelocytic leukemia cells in vitro and in vivo', Journal of Cellular Physiology, 231, (3) pp. 688-697. ISSN 0021-9541 (2015) [Refereed Article]

DOI: 10.1002/jcp.25119 [eCite] [Details]

Citations: Scopus - 5Web of Science - 5

Co-authors: Lowenthal RM; Woods GM; Holloway AF

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2015Blackburn NB, Charlesworth JC, Marthick JR, Tegg EM, Marsden KA, et al., 'A retrospective examination of mean relative telomere length in the Tasmanian Familial Hematological Malignancies Study', Oncology Reports, 33, (1) pp. 25-32. ISSN 1791-2431 (2015) [Refereed Article]

DOI: 10.3892/or.2014.3568 [eCite] [Details]

Citations: Scopus - 4Web of Science - 4

Co-authors: Blackburn NB; Charlesworth JC; Marthick JR; Tegg EM; Marsden KA; Lowenthal RM

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2015Cazaly E, Charlesworth J, Dickinson JL, Holloway AF, 'Genetic determinants of epigenetic patterns: providing insight into disease', Molecular Medicine, 21 pp. 400-409. ISSN 1076-1551 (2015) [Refereed Article]

DOI: 10.2119/molmed.2015.00001 [eCite] [Details]

Citations: Scopus - 1Web of Science - 1

Co-authors: Cazaly E; Charlesworth J; Holloway AF

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2015Chin SP, Marthick JR, West AC, Short AK, Chuckowree J, et al., 'Regulation of the ITGA2 gene by epigenetic mechanisms in prostate cancer', The Prostate, 75, (7) pp. 723-734. ISSN 0270-4137 (2015) [Refereed Article]

DOI: 10.1002/pros.22954 [eCite] [Details]

Citations: Scopus - 4Web of Science - 3

Co-authors: Chin SP; Marthick JR; West AC; Short AK; Chuckowree J; Polanowski AM; Thomson RJ; Holloway AF

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2015Qadi A, Taberlay PC, Phillips JL, Young A, West AC, et al., 'The leukemia inhibitory factor receptor gene is a direct target of RUNX1', Journal of Cellular Biochemistry, 117, (1) pp. 49-58. ISSN 0730-2312 (2015) [Refereed Article]

DOI: 10.1002/jcb.25246 [eCite] [Details]

Citations: Scopus - 1Web of Science - 1

Co-authors: Taberlay PC; Phillips JL; Young A; West AC; Brettingham-Moore KH; Holloway AF

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2014McWhirter RE, Critchley CR, Nicol D, Chalmers DRC, Whitton TC, et al., 'Community Engagement for Big Epidemiology: Deliberative Democracy as a Tool', Journal of Personalized Medicine, 4, (4) pp. 459-474. ISSN 2075-4426 (2014) [Refereed Article]

DOI: 10.3390/jpm4040459 [eCite] [Details]

Co-authors: McWhirter RE; Critchley CR; Nicol D; Chalmers DRC; Whitton TC; Otlowski MFA

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2014McWhirter RE, Marthick JR, Boyle JA, Dickinson JL, 'Genetic and epigenetic variation in vulvar cancer: Current research and future clinical practice', The Australian and New Zealand Journal of Obstetrics and Gynaecology, 54, (5) pp. 406-411. ISSN 1479-828X (2014) [Refereed Article]

DOI: 10.1111/ajo.12241 [eCite] [Details]

Citations: Scopus - 2Web of Science - 3

Co-authors: McWhirter RE; Marthick JR

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2014McWhirter RE, Thomson RJ, Marthick JR, Rumbold AR, Brown MA, et al., 'Runs of homozygosity and a cluster of vulvar cancer in young Australian Aboriginal women', Gynecologic Oncology, 133, (3) pp. 421-426. ISSN 0090-8258 (2014) [Refereed Article]

DOI: 10.1016/j.ygyno.2014.03.566 [eCite] [Details]

Citations: Scopus - 5Web of Science - 5

Co-authors: McWhirter RE; Thomson RJ; Marthick JR

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2014Young A, Berry R, Holloway AF, Blackburn NB, Dickinson JL, et al., 'RNA-seq profiling of a radiation resistant and radiation sensitive prostate cancer cell line highlights opposing regulation of DNA repair and targets for radiosensitization', BMC Cancer, 14 Article 808. ISSN 1471-2407 (2014) [Refereed Article]

DOI: 10.1186/1471-2407-14-808 [eCite] [Details]

Citations: Scopus - 6Web of Science - 5

Co-authors: Young A; Berry R; Holloway AF; Blackburn NB; Phillips JL; Brettingham-Moore KH

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2014Chalmers D, McWhirter RE, Nicol D, Whitton T, Otlowski M, et al., 'New avenues within community engagement: addressing the ingenuity gap in our approach to health research and future provision of health care', Journal of Responsible Innovation, 1, (3) pp. 321-328. ISSN 2329-9460 (2014) [Refereed Article]

DOI: 10.1080/23299460.2014.963002 [eCite] [Details]

Co-authors: Chalmers D; McWhirter RE; Nicol D; Whitton T; Otlowski M; Critchley C

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2013Lowenthal RM, Tegg EM, Dickinson JL, 'The Familial Tasmanian Haematological Malignancies Study (FaTHMS): its origins, its history and the phenomenon of anticipation', Transfusion and Apheresis Science, 49, (2) pp. 113-115. ISSN 1473-0502 (2013) [Contribution to Refereed Journal]

DOI: 10.1016/j.transci.2013.07.011 [eCite] [Details]

Citations: Scopus - 2Web of Science - 2

Co-authors: Lowenthal RM; Tegg EM

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2013Al Olama AA, Kote-Jarai Z, Schumacher FR, Wiklund F, Berndt SI, et al., 'A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease', Human Molecular Genetics, 22, (2) pp. 408-415. ISSN 0964-6906 (2013) [Refereed Article]

DOI: 10.1093/hmg/dds425 [eCite] [Details]

Citations: Scopus - 63Web of Science - 56

Co-authors: Fitzgerald LM; Marthick JR; Patterson B

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2013McWhirter RE, Nicol D, Chalmers D, Dickinson JL, 'Body ownership and research', Journal of Law and Medicine, 21 pp. 323-329. ISSN 1320-159X (2013) [Refereed Article]

PMID: 24597380 [eCite] [Details]

Co-authors: McWhirter RE; Nicol D; Chalmers D

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2012McWhirter RE, Mununggirritj D, Marika D, Dickinson JL, Condon JR, 'Ethical genetic research in Indigenous communities: challenges and successful approaches', Trends in Molecular Medicine, 18, (12) pp. 702-708. ISSN 1471-4914 (2012) [Refereed Article]

DOI: 10.1016/j.molmed.2012.08.003 [eCite] [Details]

Citations: Scopus - 4Web of Science - 7

Co-authors: McWhirter RE

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2012Marthick JR, Dickinson JL, 'Emerging Putative Biomarkers: The Role of Alpha 2 and 6 Integrins in Susceptibility, Treatment and Prognosis', Prostate Cancer, 2012 Article 298732. ISSN 2090-3111 (2012) [Refereed Article]

DOI: 10.1155/2012/298732 [eCite] [Details]

Co-authors: Marthick JR

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2011Ellis JA, Ponsonby AL, Pezic A, Williamson E, Cochrane JA, et al., 'APOE Genotype and Cardio-Respiratory Fitness Interact to Determine Adiposity in 8-Year-Old Children from the Tasmanian Infant Health Survey', PL o S One, 6, (11) Article e26679. ISSN 1932-6203 (2011) [Refereed Article]

DOI: 10.1371/journal.pone.0026679 [eCite] [Details]

Citations: Scopus - 6Web of Science - 6

Co-authors: Ponsonby AL; Cochrane JA; Dwyer T

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2011Kote-Jarai Z, Al Olama AA, Giles GG, Severi G, Schleutker J, et al., 'Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study', Nature Genetics, 43, (8) pp. 785-791. ISSN 1061-4036 (2011) [Refereed Article]

DOI: 10.1038/ng.882 [eCite] [Details]

Citations: Scopus - 176Web of Science - 165

Co-authors: Fitzgerald L; Marthick JR; Patterson B

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2011Ritchie ME, Liu R, Carvalho BS, Bahlo M, Booth DR, et al., 'Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips', BMC Bioinformatics, 12 Article 68. ISSN 1471-2105 (2011) [Refereed Article]

DOI: 10.1186/1471-2105-12-68 [eCite] [Details]

Citations: Scopus - 22Web of Science - 22

Co-authors: Foote SJ; Stankovich J; Taylor BV; Drysdale K; Guru P; Hoban E; McMorran BJ; Polanowski A; Whittock L; Perera D

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2011Chin SP, Dickinson JL, Holloway AF, 'Epigenetic regulation of prostate cancer', Clinical Epigenetics, 2, (2) pp. 151-169. ISSN 1868-7075 (2011) [Refereed Article]

DOI: 10.1007/s13148-011-0041-7 [eCite] [Details]

Citations: Scopus - 21Web of Science - 12

Co-authors: Chin SP; Holloway AF

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2011Tegg EM, Thomson RJ, Stankovich JM, Banks A, Marsden KA, et al., 'Anticipation in familial hematologic malignancies', Blood, 117, (4) pp. 1308-1310. ISSN 0006-4971 (2011) [Refereed Article]

DOI: 10.1182/blood-2010-07-296475 [eCite] [Details]

Citations: Scopus - 8Web of Science - 7

Co-authors: Tegg EM; Thomson RJ; Stankovich JM; Banks A; Marsden KA; Lowenthal RM; Foote SJ

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2010Bahlo M, Stankovich J, Danoy P, Hickey PF, Taylor BV, et al., 'Saliva-Derived DNA Performs Well in Large-Scale, High-Density Single-Nucleotide Polymorphism Microarray Studies', Cancer Epidemiology, Biomarkers and Prevention, 19, (3) pp. 794-798. ISSN 1055-9965 (2010) [Refereed Article]

DOI: 10.1158/1055-9965.EPI-09-0812 [eCite] [Details]

Citations: Scopus - 24Web of Science - 22

Co-authors: Stankovich J; Taylor BV; Foote SJ; Drysdale K; Guru P; Hoban E; McMorran BJ; Polanowski A; Whittock L; Perera D

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2010Simon KC, van der Mei IAF, Munger KL, Ponsonby A, Dickinson J, et al., 'Combined effects of smoking, anti-EBNA antibodies, and HLA-DRB1*1501 on multiple sclerosis risk', Neurology, 74, (17) pp. 1365-1371. ISSN 0028-3878 (2010) [Refereed Article]

DOI: 10.1212/WNL.0b013e3181dad57e [eCite] [Details]

Citations: Scopus - 100Web of Science - 86

Co-authors: van der Mei IAF; Ponsonby A; Dwyer T

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2010Tegg EM, Thomson RJ, Stankovich J, Banks A, Flowers C, et al., 'Evidence for a common genetic aetiology in high-risk families with multiple haematological malignancy subtypes ', British Journal of Haematology, 150, (4) pp. 456-462. ISSN 0007-1048 (2010) [Refereed Article]

DOI: 10.1111/j.1365-2141.2010.08267.x [eCite] [Details]

Citations: Scopus - 6Web of Science - 6

Co-authors: Tegg EM; Thomson RJ; Stankovich J; Banks A; Flowers C; McWhirter R; Panton J; Piaszczyk A; Bahlo M; Marsden KA; Lowenthal RM; Foote SJ

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2010van der Mei IAF, Ponsonby AL, Taylor BV, Stankovich J, Dickinson JL, et al., 'Human Leukocyte Antigen-DR15, Low Infant Sibling Exposure and Multiple Sclerosis: Gene-Environment Interaction', Annals of Neurology, 67, (2) pp. 261-265. ISSN 0364-5134 (2010) [Refereed Article]

DOI: 10.1002/ana.21849 [eCite] [Details]

Citations: Scopus - 18Web of Science - 15

Co-authors: van der Mei IAF; Ponsonby AL; Taylor BV; Stankovich J; Foote S; Dwyer T

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2009Dickinson JL, Perera DI, van der Mei AF, Ponsonby AL, Polanowski AM, et al., 'Past environmental sun exposure and risk of multiple sclerosis: a role for the Cdx-2 Vitamin D receptor variant in this interaction ', Multiple Sclerosis, 15, (5) pp. 563-570. ISSN 1352-4585 (2009) [Refereed Article]

DOI: 10.1177/1352458509102459 [eCite] [Details]

Citations: Scopus - 53Web of Science - 49

Co-authors: Perera DI; van der Mei AF; Ponsonby AL; Polanowski AM; Thomson RJ; Taylor BV; Stankovich J; Dwyer T

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2009Eeles RA, Kote-Jarai Z, Amin Al Olama A, Giles GG, Guy M, et al., 'Identification of seven new prostate cancer susceptibility loci through a genome-wide association study', Nature Genetics, 41, (10) pp. 1116-1121. ISSN 1061-4036 (2009) [Refereed Article]

DOI: 10.1038/ng.450 [eCite] [Details]

Citations: Scopus - 302Web of Science - 284

Co-authors: Fitzgerald LM; Polanowski AM; Patterson B; The UK ProtecT Study The PRACTICAL Consortium

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2009Fitzgerald LM, Patterson B, Thomson RJ, Polanowski AM, Quinn SJ, et al., 'Identification of a prostate cancer susceptibility gene on chromosome 5p13q12 associated with risk of both familial and sporadic disease', European Journal of Human Genetics, 17 pp. 368-377. ISSN 1018-4813 (2009) [Refereed Article]

DOI: 10.1038/ejhg.2008.171 [eCite] [Details]

Citations: Scopus - 18Web of Science - 18

Co-authors: Fitzgerald LM; Patterson B; Thomson RJ; Polanowski AM; Quinn SJ; Mackey DA; Dwyer T; Foote SJ; Stankovich J; McKay JD

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2008Dwyer T, Blizzard L, Patterson B, Ponsonby A-L, Martin K, et al., 'Association between birth weight and adolescent systolic blood pressure in a caucasian birth cohort differs according to skin type, CRH promoter or 11β-HSD2 genotype', Archives of Disease in Childhood, 93, (9) pp. 760-767. ISSN 0003-9888 (2008) [Refereed Article]

DOI: 10.1136/adc.2007.129122 [eCite] [Details]

Citations: Scopus - 3Web of Science - 3

Co-authors: Dwyer T; Blizzard L; Patterson B; Ponsonby A-L; Martin K; Quinn S; Sale MM; Richards SM

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2008Dwyer T, Van der Mei IAF, Ponsonby AL, Taylor BVM, Stankovich J, et al., 'Melanocortin 1 receptor genotype, past environmental sun exposure, and risk of multiple sclerosis', Neurology, 71, (8) pp. 583-589. ISSN 0028-3878 (2008) [Refereed Article]

DOI: 10.1212/01.wnl.0000323928.57408.93 [eCite] [Details]

Citations: Scopus - 31Web of Science - 32

Co-authors: Dwyer T; Van der Mei IAF; Ponsonby AL; Taylor BVM; Stankovich J; Thomson Russell; Polanowski AM

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2008Ponsonby AL, Blizzard CL, Pezic A, Cochrane JA, Ellis JA, et al., 'Adiposity Gain During Childhood, ACE I/D Polymorphisms and Metabolic Outcomes', Obesity, 16, (9) pp. 2141-2147. ISSN 1930-7381 (2008) [Refereed Article]

DOI: 10.1038/oby.2008.302 [eCite] [Details]

Citations: Scopus - 11Web of Science - 8

Co-authors: Ponsonby AL; Blizzard CL; Cochrane JA; Sale MM; Richards SM; Dwyer T

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2008Wray BN, Stankovich J, Whittock LD, Dwyer T, Ponsonby AL, et al., 'CTLA-4 and multiple sclerosis: The A49G single nucleotide polymorphism shows no association with multiple sclerosis in a Southern Australian population', Journal of Neuroimmunology, 196, (1-2) pp. 139-142. ISSN 0165-5728 (2008) [Refereed Article]

DOI: 10.1016/j.jneuroim.2008.02.001 [eCite] [Details]

Citations: Scopus - 9Web of Science - 8

Co-authors: Wray BN; Stankovich J; Whittock LD; Van der Mei IAF; Taylor BVM; Foote SJ; McMorran BJ

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2008Fitzgerald LM, Thomson RJ, Polanowski AM, Patterson B, McKay JD, et al., 'Sequence variants of α-methylacyl-CoA racemase are associated with prostate cancer risk: A replication study in an ethnically homogeneous population', The Prostate, 68, (13) pp. 1373-1379. ISSN 0270-4137 (2008) [Refereed Article]

DOI: 10.1002/pros.20798 [eCite] [Details]

Citations: Scopus - 10Web of Science - 10

Co-authors: Fitzgerald LM; Thomson RJ; Polanowski AM; Patterson B; Stankovich J

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2007Thomson Russell, Quinn SJ, McKay JD, Silver J, Bahlo M, et al., 'The advantages of dense marker sets for linkage analysis with very large families', Human Genetics, 121, (3-4) pp. 459-468. ISSN 0340-6717 (2007) [Refereed Article]

DOI: 10.1007/s00439-007-0323-5 [eCite] [Details]

Citations: Scopus - 2Web of Science - 2

Co-authors: Thomson Russell; Quinn SJ; McKay JD; Fitzgerald LM; Foote SJ; Stankovich J

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2006Dickinson JL, Sale MM, Passmore A, Fitzgerald LM, Wheatley CM, et al., 'Mutations in the NDP gene: contribution to Norrie disease, familial exudative vitreoretinopathy and retinopathy of prematurity', Clinical and Experimental Ophthalmology, 34, (7) pp. 682-688. ISSN 1442-6404 (2006) [Refereed Article]

DOI: 10.1111/j.1442-9071.2006.01314.x [eCite] [Details]

Citations: Scopus - 48Web of Science - 38

Co-authors: Sale MM; Passmore A; Fitzgerald LM; Burdon KP; Mackey DA

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2004Burdon KP, Wirth MG, Mackey DA, Russell-Eggitt IM, Craig JE, et al., 'A novel mutation in the Connexin 46 gene causes autosomal dominant congenital cataract with incomplete penetrance', Journal of Medical Genetics, 41, (8) pp. e106-109. ISSN 0022-2593 (2004) [Refereed Article]

DOI: 10.1136/jmg.2004.018333 [eCite] [Details]

Citations: Scopus - 42Web of Science - 43

Co-authors: Burdon KP; Mackey DA; Craig JE; Sale MM

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2004Burdon KP, Wirth MG, Mackey DA, Russell-Eggitt IM, Craig JE, et al., 'Investigation of crystallin genes in familial cataract, and report of two disease associated mutations', British Journal of Ophthalmology , 88, (1) pp. 79-83. ISSN 0007-1161 (2004) [Refereed Article]

DOI: 10.1136/bjo.88.1.79 [eCite] [Details]

Citations: Scopus - 61Web of Science - 50

Co-authors: Burdon KP; Mackey DA; Craig JE; Sale MM

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2004Dwyer T, Stankovich J, Blizzard CL, Fitzgerald LM, Dickinson JL, et al., 'Does the Addition of Information on Genotype Improve Prediction of the Risk of Melanoma and Nonmelanoma Skin Cancer beyond That Obtained from Skin Phenotype?', American Journal of Epidemiology, 159, (9) pp. 826-833. ISSN 0002-9262 (2004) [Refereed Article]

DOI: 10.1093/aje/kwh120 [eCite] [Details]

Citations: Scopus - 44Web of Science - 43

Co-authors: Dwyer T; Stankovich J; Blizzard CL; Fitzgerald LM; Reilly A; Sale MM

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2003Burdon KP, Wilkinson RM, Barbour JM, Dickinson JL, Stankovich J, et al., 'Investigation of albinism genes in congenital esotropia', Molecular Vision, 9, (83-85 ) pp. 710-714. ISSN 1090-0535 (2003) [Refereed Article]

PMID: 14685142 [eCite] [Details]

Citations: Scopus - 6Web of Science - 4

Co-authors: Burdon KP; Stankovich J; Mackey DA; Sale MM

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2002Rubio J, Bahlo M, Butzkueven H, Van der Mei IAF, Sale MM, et al., 'Genetic dissection of the human leukocyte antigen region by use of haplotypes of Tasmanians with multiple sclerosis', American Journal of Human Genetics, 70, (5) pp. 1125-1137. ISSN 0002-9297 (2002) [Refereed Article]

DOI: 10.1086/339932 [eCite] [Details]

Citations: Scopus - 76Web of Science - 69

Co-authors: Van der Mei IAF; Sale MM; Groom PS; Taylor BVM; Dwyer T; Foote SJ

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2002Sale MM, Craig JE, Charlesworth JC, Fitzgerald LM, Hanson I, et al., 'Broad Phenotypic variability in a Single Pedigree With a Novel 1410delC Mutation in the PST Domain of the PAX6 Gene', Human Mutation, 20, (4) pp. 322. ISSN 1098-1004 (2002) [Refereed Article]

DOI: 10.1002/humu.9066 [eCite] [Details]

Citations: Web of Science - 31

Co-authors: Sale MM; Craig JE; Charlesworth JC; Fitzgerald LM; Mackey DA

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2002Sale MM, Fitzgerald LM, Kagame K, Erdmann I, Craig JE, et al., 'Investigation of the prevalence of the myocilin Q368STOP mutation in Ugandan glaucoma patients', Ophthalmic Genetics, 33, (1) pp. 67-69. ISSN 1381-6810 (2002) [Letter or Note in Journal]

[eCite] [Details]

Co-authors: Sale MM; Fitzgerald LM; Craig JE

2002Stankovich J, Sale MM, Cooley HM, Bahlo M, Reilly A, et al., 'Investigation of chromosome 2q in osteoarthritis of the hand: no significant linkage in a Tasmanian population', Annals of the Rheumatic Diseases, 61, (12) pp. 1081-1084. ISSN 0003-4967 (2002) [Refereed Article]

DOI: 10.1136/ard.61.12.1081 [eCite] [Details]

Citations: Scopus - 13Web of Science - 10

Co-authors: Stankovich J; Sale MM; Cooley HM; Reilly A; Jones G

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2002Vickers JC, Craig JE, Stankovich J, McCormack GH, West AK, et al., 'The apolipoprotein epsilon 4 gene is associated with elevated risk of normal tension glaucoma', Molecular Vision, 8, (40) pp. 389-393. ISSN 1090-0535 (2002) [Refereed Article]

[eCite] [Details]

Citations: Web of Science - 67

Co-authors: Vickers JC; Craig JE; Stankovich J; McCormack GH; West AK; McCartney PJ; Mackey DA

2002Wheatley C, Dickinson JL, Mackey DA, Craig JE, Sale MM, 'Retinopathy of prematurity: recent advances in our understanding', British Journal of Ophthalmology, 86, (6) pp. 696-701. ISSN 0007-1161 (2002) [Refereed Article]

DOI: 10.1136/bjo.86.6.696 [eCite] [Details]

Citations: Scopus - 75Web of Science - 58

Co-authors: Wheatley C; Mackey DA; Craig JE; Sale MM

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2002Wheatley C, Dickinson JL, Mackey DA, Craig JE, Sale MM, 'Retinopathy of prematurity: recent advances in our understanding', Archives of Disease in Childhood, 87, (2) pp. F78-F82. ISSN 0003-9888 (2002) [Refereed Article]

DOI: 10.1136/fn.87.2.F78 [eCite] [Details]

Citations: Web of Science - 31

Co-authors: Wheatley C; Mackey DA; Craig JE; Sale MM

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2001Baird PN, Dickinson JL, Craig JE, Mackey DA, 'The Taa1 Restriction Enzyme Provides a Simple Means to Identify the Q368STOP Mutation of the Myocilin Gene in Primary Open Angle Glaucoma', American Journal of Ophthalmology, 131, (4) pp. 510-511. ISSN 0002-9394 (2001) [Refereed Article]

DOI: 10.1016/S0002-9394(00)00812-6 [eCite] [Details]

Citations: Scopus - 9Web of Science - 5

Co-authors: Mackey DA

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2001Dickinson JL, Sale MM, Craig JE, Mackey DA, 'Laboratory methods in ophthalmic genetics: obtaining DNA from patients', Ophthalmic Genetics, 22, (1) pp. 49-60. ISSN 1381-6810 (2001) [Professional, Non Refereed Article]

[eCite] [Details]

Co-authors: Sale MM; Craig JE; Mackey DA

2001Craig JE, Baird PN, Healey DL, McNaught AI, McCartney PJ, et al., 'Evidence for Genetic Heterogeneity within Eight Glaucoma Families, with the GLC1A Gln368STOP Mutation Being an Important Phenotypic Modifier', Ophthalmology, 108, (9) pp. 1607-1620. ISSN 0161-6420 (2001) [Refereed Article]

DOI: 10.1016/S0161-6420(01)00654-6 [eCite] [Details]

Citations: Scopus - 73Web of Science - 59

Co-authors: Craig JE; Mackey DA

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1999Fingert JH, Heon E, Liebmann JM, Yamamoto T, Craig JE, et al., 'Analysis of myocilin mutations in 1703 glaucoma patients from five different populations', Human Molecular Genetics, 8, (5) pp. 899-905. ISSN 0964-6906 (1999) [Refereed Article]

DOI: 10.1093/hmg/8.5.899 [eCite] [Details]

Citations: Scopus - 424Web of Science - 381

Co-authors: Mackey DA

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1999Hooper JD, Nicol DL, Dickinson JL, Eyre HJ, Scarman AL, et al., 'Testisin, a New Human Serine Proteinase Expressed by Premeiotic Testicular Germ Cells and Lost in Testicular Germ Cell Tumors', Cancer Research, 59, (13) pp. 3199-3205. ISSN 0008-5472 (1999) [Refereed Article]

PMID: 10397266 [eCite] [Details]

Citations: Scopus - 83Web of Science - 71

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1998Antalis TM, Linn ML, Donnan K, Mateo L, Gardner J, et al., 'The serine proteinase inhibitor (Serpin) plasminogen activation inhibitor type 2 protects against viral cytopathic effects by constitutive interferon alpha/beta priming', Journal of Experimental Medicine, 187, (11) pp. 1799-1811. ISSN 0022-1007 (1998) [Refereed Article]

DOI: 10.1084/jem.187.11.1799 [eCite] [Details]

Citations: Scopus - 69Web of Science - 59

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1998Dickinson JL, Norris BJ, Jensen PH, Antalis TM, 'The C-D interhelical domain of the serpin plasminogen activator inhibitor-type 2 is required for protection from TNF- induced apoptosis', Cell Death and Differentiation, 5, (2) pp. 163-171. ISSN 1350-9047 (1998) [Refereed Article]

DOI: 10.1038/sj.cdd.4400324 [eCite] [Details]

Citations: Scopus - 64Web of Science - 55

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1998Mahony D, Stringer BW, Dickinson JL, Antalis TM, 'DNase I hypersensitive sites in the 5 ' flanking region of the human plasminogen activator inhibitor type 2 (PAI-2) gene are associated with basal and tumor necrosis factor-alpha-induced transcription in monocytes', European Journal of Biochemistry, 256, (3) pp. 550-559. ISSN 0014-2956 (1998) [Refereed Article]

DOI: 10.1046/j.1432-1327.1998.2560550.x [eCite] [Details]

Citations: Scopus - 4Web of Science - 5

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1996Wang XQ, Gabrielli BG, Milligan A, Dickinson JL, Antalis TM, et al., 'Accumulation of p16CDKN2A in response to ultraviolet irradiation correlates with late S-G(2)-phase cell cycle delay', Cancer Research, 56, (11) pp. 2510-2514. ISSN 0008-5472 (1996) [Refereed Article]

[eCite] [Details]

Citations: Web of Science - 60

1995Dickinson JL, Bates EJ, Ferrante A, Antalis TM, 'Plasminogen activator inhibitor type 2 inhibits tumour necrosis factor alpha-induced apoptosis. Evidence for an alternate biological function', Journal of Biological Chemistry, 270, (46) pp. 27894-27904. ISSN 0021-9258 (1995) [Refereed Article]

DOI: 10.1074/jbc.270.46.27894 [eCite] [Details]

Citations: Scopus - 203Web of Science - 201

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1993Dickinson JL, Antalis TM, 'Tissue factor and plasminogen activator inhibitor expression in the differentiation of myeloid leukemic cells', Leukemia, 7, (6) pp. 864-871. ISSN 0887-6924 (1993) [Refereed Article]

[eCite] [Details]

Citations: Web of Science - 13

1993Reeder JA, Dickinson JL, Chenevix-Trench G, Antalis TM, 'Sodium butyrate differentially modulates plasminogen activator inhibitor type-1 urokinase plasminogen activator, and its receptor in a human colon carcinoma cell', Teratogenesis, Carcinogenesis, and Mutagenesis, 13, (2) pp. 75-88. ISSN 0270-3211 (1993) [Refereed Article]

DOI: 10.1002/tcm.1770130204 [eCite] [Details]

Citations: Scopus - 14Web of Science - 15

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1992Antalis TM, Dickinson JL, 'Control of plasminogen-activator inhibitor type 2 gene expression in the differentiation of monocytic cells', European Journal of Biochemistry, 205, (1) pp. 203-209. ISSN 0014-2956 (1992) [Refereed Article]

DOI: 10.1111/j.1432-1033.1992.tb16769.x [eCite] [Details]

Citations: Scopus - 33Web of Science - 35

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1989Halliday GM, Dickinson JL, Muller HK, 'Retinoic acid protests Langerhans' cells from the effects of the tumour promoter 12-O-tetradecanoylphorbol 13-acetate', Immunology, 67, (3) pp. 298-302. ISSN 0019-2805 (1989) [Refereed Article]

PMID: 2759656 [eCite] [Details]

Citations: Scopus - 10Web of Science - 13

Co-authors: Muller HK

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Chapter in Book

(3 outputs)
YearCitationAltmetrics
2014Nicol D, Chalmers D, McWhirter R, Dickinson J, 'Impressions on the Body, Property and Research', Persons, Parts and Property: How Should We Regulate Human Tissue in the 21st Century?, Hart Publishing Ltd, I Goold, K Greasley, J Herring, L Skene (ed), United Kingdom, pp. 9-23. ISBN 978-1849465465 (2014) [Research Book Chapter]

[eCite] [Details]

Co-authors: Nicol D; Chalmers D; McWhirter R

2013Chin PS, Dickinson JL, Holloway AF, 'Integrins in Prostate Cancer Invasion and Metastasis', Advances in Prostate Cancer, InTech, Gerhard Hamilton (ed), Croatia, pp. 621-640. ISBN 978-953-51-0932-7 (2013) [Research Book Chapter]

DOI: 10.5772/45948 [eCite] [Details]

Co-authors: Chin PS; Holloway AF

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2011Marthick JR, Holloway AF, Dickinson JL, 'Integrins as determinants of genetic susceptibility, tumour behaviour and their potential as therapeutic targets', Prostate Cancer - From Bench to Bedside, InTech, Philippe E. Spiess (ed), Rijeka, Croatia, pp. 243-266. ISBN 978-953-307-331-6 (2011) [Research Book Chapter]

DOI: 10.5772/1285 [eCite] [Details]

Co-authors: Marthick JR; Holloway AF

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Conference Publication

(22 outputs)
YearCitationAltmetrics
2011Chin PS, Short AK, West AC, Marthick JR, Holloway AF, et al., 'Regulation of the ITGA2 gene in prostate cancer', Lorne Cancer Conference , February, Lorne, Victoria (2011) [Conference Extract]

[eCite] [Details]

Co-authors: Chin PS; Short AK; West AC; Marthick JR; Holloway AF

2011Tegg E, Stankovich J, Thomson R, Perera D, Marsden K, et al., 'Whole genome sequencing of CLL case', GeneMappers, April, Hobart, Australia (2011) [Keynote Presentation]

[eCite] [Details]

Co-authors: Tegg E; Stankovich J; Thomson R; Perera D; Marsden K; Lowenthal R; Flowers C; Banks A; Piaszczyk A; Foote S

2011Dickinson J, Stankovich J, Thomson R, Tegg E, Marsden K, et al., 'Identification of Susceptibility Genes for Haematological Maligancies', GeneMappers, April, Hobart, Australia (2011) [Conference Extract]

[eCite] [Details]

Co-authors: Stankovich J; Thomson R; Tegg E; Marsden K; Lowenthal R; Flowers C; Banks A; Piaszczyk A; Foote S

2010Koutoulis L, Garry JA, Dickinson JL, Foote SJ, 'Now all I need is a wife', Australasian Research Management Conference , September, Fremantle, Western Australia (2010) [Conference Extract]

[eCite] [Details]

Co-authors: Koutoulis L; Garry JA; Foote SJ

2010Patterson B, Short A, Polanowski AM, Marthick JR, Thomson R, et al., 'A role for integrin alpha 2 in familial prostate cancer susceptibility', kConFab: Familial Aspects of Cancer: Research and Practice, August, Kingscliff, Queensland (2010) [Conference Extract]

[eCite] [Details]

Co-authors: Patterson B; Short A; Polanowski AM; Marthick JR; Thomson R; Stankovich J

2010Tegg E, Stankovich J, Thomson R, Perera D, Marsden K, et al., 'Familial Haematological malignancies: The Tasmanian experience', Haematology Society of Australia and New Zealand, Australia and New Zealand Society for Blood Transfusion & Australasian Society for Thrombosis and Homeostasis (2010) [Keynote Presentation]

[eCite] [Details]

Co-authors: Tegg E; Stankovich J; Thomson R; Perera D; Marsden K; Lowenthal R; Flowers C; Banks A; Piaszczyk A; Foote S

2009Short AK, West AC, Patterson B, Polanowski A, Holloway AF, et al., 'Methylation of the ITGA2 promoter in Prostate Cancer', Epigenetics Conference, Melbourne, Australia (2009) [Conference Extract]

[eCite] [Details]

Co-authors: Short AK; West AC; Patterson B; Polanowski A; Holloway AF

2009Tegg E, Stankovich J, Thomson R, Perera D, Marsden K, et al., 'Familial Haematological Malignancies', GeneMappers (2009) [Conference Extract]

[eCite] [Details]

Co-authors: Tegg E; Stankovich J; Thomson R; Perera D; Marsden K; Lowenthal R; Flowers C; Banks A; Piaszczyk A; Foote S

2008Simon KC, Van der Mei IAF, Munger KL, Ponsonby AL, Dickinson JL, et al., 'Smoking as an independent risk factor for multiple sclerosis: considering possible combined effects with the human leukocyte antigen DR15 genotype and anti-EBNA antibody titers', Sage Publications Ltd, 17-20 September, Montreal, Canada, pp. Vol 14 (1) p,200. (2008) [Conference Edited]

[eCite] [Details]

Co-authors: Van der Mei IAF; Ponsonby AL; Dwyer T

2008Van der Mei IAF, Ponsonby AL, Taylor BVM, Stankovich J, Dickinson JL, et al., 'A potentiation of the adverse effect of human leukocyte antigen-DR15 on the risk of multiple sclerosis by low infant sibling exposure: a population based case-control study', Sage Publications Ltd, 17-20 September, Montreal, Canada, pp. Vol 14 (1) S201-S202. (2008) [Conference Edited]

[eCite] [Details]

Co-authors: Van der Mei IAF; Taylor BVM; Stankovich J; Foote SJ

2007Perera D, Tegg E, Stankovich J, Thomson R, Silver J, et al., 'Linkage analysis of a large Tasmanian haematological cancer family', GeneMappers (2007) [Conference Extract]

[eCite] [Details]

Co-authors: Perera D; Tegg E; Stankovich J; Thomson R; Marsden K; Lowenthal R; Flowers C; Banks A; Piaszczyk A; Foote S

2007Tegg E, Stankovich J, Thomson R, Perera D, Marsden K, et al., 'The Tasmanian familial leukaemia and lymphoma research study', Haematology Society of Australia and New Zealand, Australia and New Zealand Society for Blood Transfusion & Australasian Society for Thrombosis and Homeostasis (2007) [Conference Extract]

[eCite] [Details]

Co-authors: Tegg E; Stankovich J; Thomson R; Perera D; Marsden K; Lowenthal R; Flowers C; Banks A; Piaszczyk A; Foote S

2007Tegg E, Stankovich J, Thomson R, Perera D, Marsden K, et al., 'The Tasmanian familial leukaemia and lymphoma research study', GeneMappers (2007) [Conference Extract]

[eCite] [Details]

Co-authors: Tegg E; Stankovich J; Thomson R; Perera D; Marsden K; Lowenthal R; Flowers C; Banks A; Piaszczyk A; Foote S

2006Dickinson J, Thomson R, Patterson B, Polanowski A, Stankovich J, et al., 'Prostate Cancer Sun Exposure and Genes Modifying Risk', 11th International Congress of Human Genetics, 6-10th August, Brisbane, Australia (2006) [Conference Extract]

[eCite] [Details]

Co-authors: Thomson R; Polanowski A; Stankovich J; Fryer J; Blizzard L

2005Dickinson JL, Patterson B, Polanowski A, Thomson R, Dwyer T, et al., 'Prostate Cancer: Sun Exposure and Genes Modifying Risk', American Society of Human Genetics Conference, October, Salt Lake City, Utah (2005) [Conference Extract]

[eCite] [Details]

Co-authors: Patterson B; Polanowski A; Thomson R; Blizzard L; Fryer J; McKay J

2005Foote SJ, Rubio JP, Bahlo M, Kilpatrick TJ, Speed TP, et al., 'Multiple Sclerosis: a haplotype association study', Novartis Foundation Symposium, 2005, pp. 31-39. (2005) [Conference Extract]

[eCite] [Details]

Co-authors: Foote SJ; Stankovich J; Taylor BVM; Sale MM; Van der Mei IAF; Groom PS

2005McKay J, Fitzgerald L, Stankovich J, Banks A, Hazelwood K, et al., 'Linkage analysis of a second large prostate cancer family from southern Tasmania, Australia', American Society of Human Genetics Conference, October, Salt Lake City, Utah (2005) [Conference Extract]

[eCite] [Details]

Co-authors: Fitzgerald L; Stankovich J; Banks A; Hazelwood K

2001Dickinson JL, Wheatley CM, Fitzgerald L, Brown M, Craig JE, et al., 'Investigation of a possible role for the Norrie Disease gene in Retinopathy of Prematurity', Human Genome Society Conference, Cairns, Australia (2001) [Conference Extract]

[eCite] [Details]

2000Mackey DA, Green C, Sale MM, Craig JE, Dickinson JL, et al., 'Familial aggregation of glaucoma: Experience with the glaucoma inheritance study in Tasmania (GIST)', The Association for Research in Vision and Ophthalmology, April 30-May 5, 2000, Fort Lauderdale, Florida, pp. S527. (2000) [Conference Extract]

[eCite] [Details]

Co-authors: Mackey DA; Sale MM; Craig JE; Stanwix SP; McCartney PJ

2000Sale MM, Craig JE, Dickinson JL, Love J, Hanson I, et al., 'Phenotypic variability in a large aniridia pedigree with a novel PAX6 1410delC', The Association for Research in Vision and Ophthalmology, April 30-May 5, 2000, Fort Lauderdale, Florida, pp. S822. (2000) [Conference Extract]

[eCite] [Details]

Co-authors: Sale MM; Craig JE; Mackey DA

1998Dickinson JL, Mackey DA, Craig JE, McNaught AI, Wilkinson CH, et al., 'Predictive DNA testing for glaucoma with the GLC1A gene: experience with a large Australian family', International Human Genome Conference, Brisbane, Australia (1998) [Conference Extract]

[eCite] [Details]

1995Dickinson JL, Antalis TM, 'Evidence that the Active Site and the C-D interhelical region of plasminogen activator inhibitor type 2 are required for protection from TNFa induced apoptosis', Fifth International Workshop on the Molecular and Cellular Biology of Plasminogen Activation, Finland (1995) [Keynote Presentation]

[eCite] [Details]

Grants & Funding

Funding Summary

Number of grants

59

Total funding

$14,877,318

Projects

Investigation of chromosomal loss and gain at 7p21 in a Tasmanian hereditary prostate cancer family (2017)$23,186
Description
This project aims to fine-map and determine the underlying cause of chromosomal loss and gain at 7p21 in a Tasmanian hereditary prostate cancer family. This region contains a candidate gene, ETV1, which is known to be translocated in ~7% of tumours and increases the invasive and metastatic potential of tumours. Emerging therapies targeting this translocation could improve outcomes in Tasmanian men with prostate cancer.
Funding
Royal Hobart Hospital Research Foundation ($23,186)
Scheme
Grant-Establishment
Administered By
University of Tasmania
Research Team
Fitzgerald LM; Dickinson JL; Malley RC; Donovan S; Dun Karen; Diano G; Skala M; Redwig F
Year
2017
Developing CRISPR/Cas Library Screens for identifying Novel Cancer Therapies (2017)$63,845
Description
Our understanding of many cancers has improved dramatically over the past decade predominantly due to our ability to sequence entire genomes, at scale. Yet, we still require a better understanding of the underlying mechanisms that initiate and perpetuate cancers, as well as gene-based factors that initiate the transition from indolent to aggressive cancers with a propensity to metastasize. CRISPR/Cas is proving a robust, powerful and necessary tool in the laboratory that will undoubtedly underpin the next breakthrough in the field of cancer. As such, it is essential that we develop this capability at the University of Tasmania in a timely manner.The specific AIMS of this proposal are to:Aim 1: Establish CRISPR/Cas screening at the University of Tasmania as a tool to identify genesthat drive aggressive and metastatic cancers.Aim 2: Perform a genome-wide CRISPR/Cas negative selection (loss-of-function) screen toidentify genes essential for proliferation and survival, as well as metastatic behaviour.
Funding
University of Tasmania Foundation Inc ($63,845)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
Taberlay PC; Hewitt A; Holloway AF; Liu G; Dickinson JL; Brettingham-Moore KH; Fitzgerald L; Eri RD; Cook AL
Year
2017
David Collins Leukaemia Foundation Elite Research Scholarship - Epigenetic and Transcriptional regulation of leukaemia (2016 - 2019)$153,000
Description
This project will investigate how epigenetic and transcription factors co-operate to control gene expression, how this is reprogrammed in leukaemia and how epigenetic drugs impact these gene expression programs.
Funding
David Collins Leukaemia Foundation ($153,000)
Scheme
Donation - Individual
Administered By
University of Tasmania
Research Team
Holloway AF; Dickinson JL; Brettingham-Moore KH
Period
2016 - 2019
Molecular biomarkers for seabird age estimation (2016)$800
Description
The aim of my research is to develop and implement a non-lethal method to accurately and reliably estimate the age of individual long-lived seabirds.
Funding
Linnean Society of New South Wales ($800)
Scheme
Grant-Joyce W Vickery Scientific Research Fund
Administered By
University of Tasmania
Research Team
Hindell MA; McMahon CR; Dickinson JL; Jarman SN; De Paoli-Iseppi R
Year
2016
Molecular biomarkers for seabird age estimation. (2016)$7,500
Description
The aim of my research is to develop and implement a non-lethal method to accurately and reliably estimate the age of individual long-lived seabirds.
Funding
Holsworth Wildlife Research Endowment ($7,500)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Hindell MA; Dickinson JL; McMahon CR; Jarman SN; Deagle BE; De Paoli-Iseppi R
Year
2016
DNA sequencer for genetic research (2015)$80,000
Description
Purchase of a 3500 Genetic Analyzer for the sequencing of DNA to support genetic and molecular research.
Funding
Ian Potter Foundation ($80,000)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Burdon KP; Dickinson JL
Year
2015
Epigenetic regulation of inegrin beta 4 as a predictor of prostate cancer progression (2015)$14,750
Description
Prostate cancer diagnoses continue to rise rapidly in Australia, but of most concern is ourcurrent inability to distinguish aggressive tumours with propensity to metastasize from moreindolent disease. This results in unnecessary treatment of many men whose cancer may neverprogress to clinically significant disease. However, progression of the disease results in aggressive, metastatic tumours which are difficult to treat and are associated with poor prognosis. We thus urgently require a better understanding of the underlying drivers of this disease, and particularly the factors and mechanisms that drive the transition to more aggressive tumours with a propensity to spread. These factors may represent biomarkers and potential therapeutic targets in prostate cancer progression.The aims of this study are therefore:1.To determine whether epigenetic changes at the ITGB4 gene are associated with its increased expression in prostate cancer progression, and 2. To investigate whether epigenetic changes at the ITGB4 gene in prostate cancer are driven by the RUNX transcription factors.
Funding
Cancer Council of Tasmania ($14,750)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
Holloway AF; Dickinson JL; Brettingham-Moore KH; Rao S; Black Allison
Year
2015
A vulvar cancer cluster caused by genetic susceptibility: investigating the genetic mechanism (2014 - 2016)$1,116,905
Description
Cancer of the vulva is 70 times more common in young Aboriginal women in Arnhem Land than in other women. Human Papillomavirus (HPV), which also causes cervical cancer, is the usual cause of this cancer; initial investigations have found that HPV is present in these cancers but is not the reason for the excessive incidence. This study will investigate inherited risk factors contributing to the development of this diseasein this population.
Funding
National Health & Medical Research Council ($1,116,905)
Scheme
Grant-Project
Administered By
Menzies School of Health Research
Research Team
Condon J; Dickinson JL; McWhirter R; Rumbold A; Thomson RJ; Boyle J; Garvey G; Markey P
Period
2014 - 2016
Grant Reference
1060187
Familial Haematological Malignancies: understanding the role of inherited causative factors (2014)$20,000
Description
Genetic factors are known to contribute to the risk of developing haematological malignancies, however to date the underlying genetic drivers of disease development remain largely unknown. Knowing the causative genes is not only important in understanding the disease process but also provides a range of benefits in the diagnosis, development of tailored treatments, and identification of new targets for therapy. Studying families with multiple cases of these diseases is a powerful approach used to identify the causative genes.
Funding
Cancer Council of Tasmania ($20,000)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
Dickinson JL; Charlesworth JC; Foote SJ; Thomson RJ; Holloway AF; Lowenthal RM
Year
2014
Intersection of RUNX and integrin families in leukaemia (2014 - 2015)$30,000
Funding
David Collins Leukaemia Foundation ($30,000)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Holloway AF; Dickinson JL
Period
2014 - 2015
The role of epigenetic changes in the progression of clinical disease in Multiple Endocrine Neoplasia Type 1 (MEN 1) (2013)$22,500
Funding
Royal Hobart Hospital Research Foundation ($22,500)
Scheme
Grant-Research
Administered By
University of Tasmania
Research Team
Burgess JR; Prentice L; Holloway AF; Dickinson JL
Year
2013
Combining deep sequencing and linkage approaches to identify rare variants contributing to familial prostate cancers (2013 - 2014)$35,000
Funding
Cancer Council of Tasmania ($35,000)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
Dickinson JL; Thomson RJ; Charlesworth JC; Holloway AF; Jarman SN
Period
2013 - 2014
Genetic aetiology of familial haematological malignancies (2013 - 2014)$35,000
Description
The project outlines the genetic analysis of a rare resource, utilising high density SNP genotyping to perform familial linkage analysis of twelve large families. It will identify genes predisposing to haematological malignancies in a novel dataset.
Funding
Cancer Council of Tasmania ($35,000)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
Dickinson JL; Charlesworth JC; Thomson RJ; Lowenthal RM
Period
2013 - 2014
Regulation of integrins by RUNX1 in leukaemia (2013)$30,000
Funding
David Collins Leukaemia Foundation ($30,000)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Holloway AF; Dickinson JL; Brettingham-Moore KH
Year
2013
Regulation of Integrin Gene Expression Programs by RUNX in Cancer (2013 - 2016)$26,250
Description
The incidence of leukaemia continues to increase in Tasmania despite advances in our understanding and treatment of the disease. A gene which is often disrupted in leukaemia is a master regulator called RUNX1, which controls how and when other genes are switched on in blood cells. This project hypothesises that RUNX1 controls cell surface molecules called integrins. It proposes that disruption of RUNX1 in blood cells leads to the development of leukaemia by altering the integrins on the surface of the cells.
Funding
Cancer Council of Tasmania ($26,250)
Scheme
Scholarship-PhD Top-Up Grant
Administered By
University of Tasmania
Research Team
Holloway AF; Dickinson JL
Period
2013 - 2016
Role of NF-kB in radiosensitivity and resistance in prostate cancer (2012)$19,200
Funding
Cancer Council of Tasmania ($19,200)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
Brettingham-Moore KH; Dickinson JL; Skala M
Year
2012
Prostate cancer risk variants in integrin genes & their role in prostate cancer development (2012)$49,362
Funding
Cancer Council of Tasmania ($49,362)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
Dickinson JL; Holloway AF; McMorran BJ; Thomson RJ
Year
2012
Identifying inherited factors underlying familial haematological malignancies (2012)$49,362
Funding
David Collins Leukaemia Foundation ($49,362)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Dickinson JL; Stankovich J; Charlesworth JC; Lowenthal RM; Marsden KA; Tegg EM
Year
2012
Inherited determinants of Cancer Aetiology (2012 - 2016)$644,028
Description
Family history of cancer is a strong risk factor for many cancers. Whilst very significant advances have been made in our understanding of common genetic variations contributing to cancer risk, the genetic factors contributing to the inherited portion of cancer risk and those factors influencing disease course remain poorly understood. Current opinion is that the study of families with multiple cases of inherited disease will be a fruitful, alternative approach to gene discovery in human complex disease. This project aims to identify those genetic factors contributing to familial cancer risk and disease course utilising the Tasmanian Familial Cancer Genetics Resources established at the Menzies Research Institute Tasmania.
Funding
Australian Research Council ($644,028)
Scheme
Fellowship-Future
Administered By
University of Tasmania
Research Team
Dickinson JL
Period
2012 - 2016
Grant Reference
FT120100623
A vulvar cancer cluster in young Indigenous women in Arnhem Land: investigation of community knowledge, genetic susceptibility and supportive care response (2011 - 2012)$692,042
Funding
National Health & Medical Research Council ($692,042)
Scheme
Grant-Project
Administered By
Menzies School of Health Research
Research Team
Condon J; McGrath Pam; Rumbold A; Davy M; Tabrizi S; Jamieson S; Taylor-Thomson D; Dickinson JL; Thomson RJ
Period
2011 - 2012
Grant Reference
1003817
Epigenomics of familial prostate cancer (2011)$14,000
Funding
Cancer Council of Tasmania ($14,000)
Scheme
Grant-Small
Administered By
University of Tasmania
Research Team
Charlesworth JC; Holloway AF; Dickinson JL
Year
2011
Prostate cancer risk variants in integrin genes and their role in tumour development (2011)$10,000
Funding
Cancer Council of Tasmania ($10,000)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
Dickinson JL; Holloway AF; McMorran BJ; Patterson B; Thomson RJ
Year
2011
Epigenetic Regulation of the integrin, ITGA2, in Tumour Development (2011)$10,000
Funding
Cancer Council of Tasmania ($10,000)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
Dickinson JL; Holloway AF
Year
2011
Identification of susceptibility genes for familial haematological malignancies (2011)$91,224
Funding
Leukaemia Foundation ($91,224)
Scheme
Grant-In-Aid
Administered By
University of Tasmania
Research Team
Dickinson JL; Foote SJ; Stankovich J; Lowenthal RM; Thomson RJ; Tegg EM; Charlesworth JC; Marsden KA
Year
2011
Transcriptome analysis for predicting response to radiotherapy in prostate cancer patients (2011)$9,091
Funding
Royal Hobart Hospital Research Foundation ($9,091)
Scheme
Grant-Research
Administered By
University of Tasmania
Research Team
Dickinson JL; Brettingham-Moore KH; Skala M; Holloway AF; Stankovich J
Year
2011
Tasmanian familial haematological malignancy research study (2011)$50,000
Funding
Pfizer ($50,000)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
Tegg EM; Lowenthal RM; Foote SJ; Dickinson JL; Thomson RJ; Stankovich J; Marsden KA
Year
2011
ITGA2: characterisation as a potential biomarker in prostate cancer (2010)$48,125
Funding
Cancer Council of Tasmania ($48,125)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
Dickinson JL; Holloway AF; Patterson B; Stankovich J; McMorran BJ
Year
2010
Identification of susceptibility genes for haematological malignancies (2010)$35,000
Funding
David Collins Leukaemia Foundation ($35,000)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Dickinson JL; Foote SJ; Stankovich J; Lowenthal RM; Thomson RJ; Bahlo M; Marsden KA
Year
2010
Tasmanian genealogical and genetic resource for cancer research (2010)$49,434
Funding
Tasmanian Community Fund ($49,434)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Dickinson JL
Year
2010
Elucidation of the role of the integrin alpha 2 gene (ITGA2) in prostate cancer (2009)$45,600
Funding
Cancer Council of Tasmania ($45,600)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
Dickinson JL; Holloway AF; Patterson B; Stankovich J; McMorran BJ
Year
2009
Investigating the genetics of familial haematological cancers in Tasmania (2009)$29,132
Funding
David Collins Leukaemia Foundation ($29,132)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Dickinson JL; Foote SJ; Tegg EM; Stankovich J; Lowenthal RM; Marsden KA; Thomson RJ; Bahlo M
Year
2009
Integrative genomic approaches to understanding the genetics of prostate cancer (2009 - 2011)$515,699
Description
The aims of this project are to: 1) examine the contribution of 14 recently identified prostate cancer susceptibility loci to risk of disease in the Tasmanian Familial and Sporadic Prostate Cancer datasets; 2) perform genome-wide linkage analysis of selected large families with an increased incidence of prostate cancer to identify new cancer susceptibility loci; 3) examine these loci in the context of the results obtained from Aims 1-3; 4) prioritise genes lying within candidate intervals using a variety of expression and genomic techniques alongside bioinformatic approaches; and 5) continue to expand the Tasmanian Prostate Cancer Dataset using Tasmanian Cancer Registry records and the Menzies Genealogical Database.
Funding
Cancer Australia ($515,699)
Scheme
Grant-Priority-driven Collab. Cancer Research
Administered By
University of Tasmania
Research Team
Dickinson JL; Foote SJ; Charlesworth JC; Thomson RJ; Bahlo M
Period
2009 - 2011
Elucidation of the role of a novel susceptibility gene in prostate cancer (2008)$25,000
Funding
Cancer Council of Tasmania ($25,000)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
Dickinson JL; Holloway AF; Patterson B; McMorran BJ; Stankovich J
Year
2008
Development of the Tasmanian Familial Prostate Cancer Genetic Resource (2008)$76,588
Funding
Tasmanian Community Fund ($76,588)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Dickinson JL
Year
2008
Investigating the genetics of familial haematological cancers in Tasmania (2008)$25,000
Funding
David Collins Leukaemia Foundation ($25,000)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Dickinson JL; Foote SJ; Stankovich J; Lowenthal RM; Marsden KA; Bahlo M
Year
2008
Elucidation of the role of a novel susceptibility gene in prostate cancer (2008)$25,000
Funding
Royal Hobart Hospital Research Foundation ($25,000)
Scheme
Grant-Research
Administered By
University of Tasmania
Research Team
Dickinson JL; Holloway AF; Patterson B; McMorran BJ; Stankovich J
Year
2008
Genetic and Bioinformatic Analysis of Complex Human Diseases (2008 - 2012)$8,134,805
Funding
National Health & Medical Research Council ($8,134,805)
Scheme
Grant-Program
Administered By
University of Tasmania
Research Team
Foote SJ; Speed TP; Smyth G; Bahlo M; Chalmers DRC; Amor David; Dickinson JL
Period
2008 - 2012
Grant Reference
490037
Investigating the genetics of familial haematological cancers in Tasmania (2007)$60,000
Funding
Cancer Council of Tasmania ($60,000)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
Dickinson JL; Stankovich J; Lowenthal RM; Marsden KA; Patterson B; Quinn SJ
Year
2007
The ACRF Tasmanian Inherited Cancer Centre (ATICC) (2007 - 2009)$1,100,000
Funding
Australian Cancer Research Foundation ($1,100,000)
Scheme
Grant-Research
Administered By
University of Tasmania
Research Team
Foote SJ; Venn A; Lowenthal RM; Vickers JC; Dickinson JL; Blizzard CL; Stankovich J; Bahlo M; Chalmers DRC
Period
2007 - 2009
The Tasmanian Leukaemia and Other Haematopoietic Malignancies Research Study (2006)$40,000
Funding
Perpetual Trustees ($40,000)
Scheme
Grant-Trust Fund
Administered By
University of Tasmania
Research Team
Dickinson JL; Foote SJ
Year
2006
The Tasmanian prostate cancer genetics study (2006 - 2011)$148,500
Funding
Max Bruce Trust ($148,500)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
Dickinson JL
Period
2006 - 2011
Identification of Genes that Influence MS Progression by Pathways that Involve UV Exposure: a Prospective Cohort Study (2006 - 2007)$100,000
Funding
Ian Potter Foundation ($100,000)
Scheme
Grant
Administered By
University of Tasmania
Research Team
van der Mei IAF; Foote SJ; Dickinson JL; Ponsonby AL; Taylor BVM; Dwyer T; Blizzard CL
Period
2006 - 2007
Cancer Council Tasmania, Research Fellow (2006 - 2010)$460,000
Funding
Cancer Council of Tasmania ($460,000)
Scheme
Fellowship
Administered By
University of Tasmania
Research Team
Dickinson JL
Period
2006 - 2010
Sanyo Upright Freezer (2006)$18,590
Funding
National Health & Medical Research Council ($18,590)
Scheme
Grant-Equipment
Administered By
University of Tasmania
Research Team
Venn A; Foote SJ; Dickinson JL; Jones G
Year
2006
Grant Reference
361670
Study of Molecular Events in Large Tasmanian Prostate Cancer Families (2005)$20,000
Funding
Cancer Council of Tasmania ($20,000)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
Dickinson JL; McKay JD; Venter DJ
Year
2005
Identification of a Gene that Increases Risk of MS Via a Pathway Involving UV Exposure (2005 - 2006)$109,375
Funding
National Health & Medical Research Council ($109,375)
Scheme
Grant-Project
Administered By
University of Tasmania
Research Team
Dwyer T; McKay JD; Dickinson JL; Ponsonby AL; Taylor BVM; Quinn SJ
Period
2005 - 2006
Grant Reference
333105
Tasmanian Prostate Cancer Study: Study of Molecular Events in large Tasmanian Prostate Cancer Families (2005)$14,200
Funding
Estate of Dr R.A. Parker ($14,200)
Scheme
Grant-Charitable Purposes in Tasmania
Administered By
University of Tasmania
Research Team
Dickinson JL; McKay JD
Year
2005
Tasmanian Prostate Cancer Study (2005)$18,500
Funding
Mazda Foundation ($18,500)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Dickinson JL
Year
2005
Tasmanian Prostate Cancer Study (TASPAC) (2005 - 2007)$60,000
Funding
Perpetual Trustees ($60,000)
Scheme
Grant-Trust Fund
Administered By
University of Tasmania
Research Team
Dickinson JL; McKay JD
Period
2005 - 2007
The Tasmanian Parkinson's Disease Research Project: A Feasibility Study (2005)$14,742
Funding
Royal Hobart Hospital Research Foundation ($14,742)
Scheme
Grant-Research
Administered By
University of Tasmania
Research Team
Venn A; Dickinson JL; Srikanth V; D'Souza WJ
Year
2005
Prostate Cancer: Sun Exposure And Candidate Genes Modifying Risk (2004 - 2006)$274,275
Funding
Commonwealth Department of Veterans Affairs ($274,275)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Dwyer T; Dickinson JL; Stankovich J; Blizzard CL; McKay JD
Period
2004 - 2006
Identification of Genomic Regions Implicated in Hereditary Prostate Cancer in Tasmania by Genome-wide Scan (2004)$16,364
Funding
Royal Hobart Hospital Research Foundation ($16,364)
Scheme
Grant-Research
Administered By
University of Tasmania
Research Team
Dickinson JL; McKay JD; Fitzgerald LM
Year
2004
A Pilot Study to Examine Biological, Lifestyle and Genetic Risk Factors Associated with the Development of Multiple Non-melanoma Skin Cancers (2004)$22,000
Funding
University of Tasmania ($22,000)
Scheme
Grant-Institutional Research Scheme
Administered By
University of Tasmania
Research Team
Venn A; Dwyer T; Blizzard CL; Woods GM; Muller HK; Dickinson JL
Year
2004
Molecular Genetics of Familial Prostate Cancer in Tasmania (2003)$20,000
Funding
Cancer Council of Tasmania ($20,000)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
McKay JD; Dickinson JL
Year
2003
The MSR1 Gene and Risk of Prostate Cancer in the Tasmanian Population (2003)$11,667
Funding
Royal Hobart Hospital Research Foundation ($11,667)
Scheme
Grant-Research
Administered By
University of Tasmania
Research Team
McKay JD; Dickinson JL; Stankovich J
Year
2003
A Pilot Study to Examine Biological, Lifestyle and Genetic Risk Factors Associated with the Development of Second and Subsequent Non-melanoma Skin Cancers in People with a History of Skin Cancer (2003)$18,000
Funding
Cancer Council of Tasmania ($18,000)
Scheme
Grant-Cancer Research
Administered By
University of Tasmania
Research Team
Venn A; Dwyer T; Blizzard CL; Woods GM; Muller HK; Dickinson JL
Year
2003
Identification of Genes Causing Congenital Cataract (2002)$13,500
Funding
Royal Hobart Hospital Research Foundation ($13,500)
Scheme
Grant-Research
Administered By
University of Tasmania
Research Team
Dickinson JL; Easteal S
Year
2002
Evaluation of the Norrie Disease, VEGF-B and VEGF-A Genes in Retinopathy of Prematurity (2001)$20,000
Funding
University of Tasmania ($20,000)
Scheme
Grant-Institutional Research Scheme
Administered By
University of Tasmania
Research Team
Sale MM; Dickinson JL
Year
2001
The Glaucoma Inheritance Study in Tasmania (GIST): Investigating the Prevalence, Penetrance and Phenotype of Mutations in Genes Resulting in the Eye Disease, Glaucoma (2000)$11,177
Funding
Royal Hobart Hospital Research Foundation ($11,177)
Scheme
Grant-Research
Administered By
University of Tasmania
Research Team
Mackey DA; Dickinson JL
Year
2000

Research Supervision

Current

5

Completed

11

Current

DegreeTitleCommenced
PhDSeabird Age Estimation with Molecular Biomarkers2015
PhDEpigenetic and Transcriptional Regulation of Leukaemia2015
PhDFamilial Prostate Cancer Genetic Research Study2016
PhDCongenital Cataract Genetics in Australian Families2016
PhDTranscriptional and Epigenetic Regulation of Tumour Development and Metastasis2017

Completed

DegreeTitleCompleted
PhDRegulation of ITGA6 and ITGB4 Integrin Genes by RUNX1 and Epigenetic Mechanisms
Candidate: Jessica Louise Phillips
2017
PhDEpigenomic and Genomic Analysis of Familial Prostate Cancer
Candidate: Emma Cazaly
2017
MastersOn the Role of Risk-Associated Genetic Loci in Modulating Clinical Course in Multiple Sclerosis
Candidate: Gongbu Pan
2016
PhDThe Anti-Cancer Activity of the Natural Product, Fucoidan, in Haematological Malignancies
Candidate: Farzaneh Atashrazm
2016
PhDIdentifying Genetic Susceptibilities Underlying Familial Haematological Malignancies in a Tasmanian Family Resource
Candidate: Nicholas Bayden Blackburn
2015
PhDRegulation of the ITGA2 Gene in Prostate Cancer
Candidate: Suyin Paulynn Chin
2014
PhDRegulation of Inducible Immune Gene Expression in T Cells Compared to Macrophages
Candidate: Lucy Damaris Apps
2014
PhDRegulation of the LIFR and gp130 Genes by the RUNX1 Transcription Factor
Candidate: Abeer Ahmed Qadi
2012
PhDInvestigating the Genetic Predisposition for Familial Haematological Malignancies
Candidate: Elizabeth Mary Tegg
2011
PhDThe Genetics of Familial Prostate Cancer in Tasmania
Candidate: Liesel Maria FitzGerald
2007
PhDInvestigating the Genetics of Primary Open-Angle Glaucoma in Tasmania
Candidate: Jac Claire Charlesworth
2006