How is the Brain Circuit Wired?
The brain comprises billions of nerve cells, or neurons, that connect in an incredibly intricate and precise network. How these precise nerve connections are established during embryonic development and maintained through out life is not understood. Yet such information is fundamental if we are to understand the basis of neurological disease and injury. Our laboratory focuses on neuronal growth, investigating the mechanisms growing axons use to navigate their environment, when searching for their target cell. We combine molecular biology and biochemistry with sophisticated imaging techniques, including live cell imaging to investigate protein signaling in actively growing neurons. We also collaborate closely with other researchers to understand the mechanisms underlying neurodegenerative disease and neuronal regeneration.
Dr Lisa Foa
School of Medicine