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Angus Olding awarded Peter W. Smith CSL postgraduate prize for 2021

Picture for the award advertisement

The Peter W. Smith CSL Postgraduate Award recognises the most outstanding peer-reviewed publication in the preceding 12 months by a University of Tasmania postgraduate student that made extensive use of Central Science Laboratory facilities and expertise.

The prize honours the vision and commitment of the late Dr Peter W. Smith OAM for the formation and continued successful operation of the CSL, and was established in 2014 to commemorate the 40th anniversary of establishment of the university facility.

The recipient for 2021 is Mr Angus Olding from School of Natural Sciences – Chemistry.

Angus’ paper published in Angewandte Chemie (IF 15) investigated fundamental aspects of the Nobel Prize winning Suzuki-Miyaura (SM) cross coupling reaction and addressed a longstanding question regarding the reaction mechanism.  Angus’ work provided the first unambiguous confirmation of the structure of fundamental pre-transmetalation intermediates present in SM cross-coupling since the reaction was discovered in 1979.  The SM reaction is the most important and ubiquitous transition metal catalysed C-C cross-coupling method across both industry and academia.  For example, SM couplings comprise 40% of all C-C bond forming reactions employed in the preparation of pharmaceutical drugs.

Angus’ work made extensive use of CSL facilities and professional expertise, primarily focussed on NMR spectroscopic studies under the support of Dr James Horne.  It is estimated that 200-300 hours of measurement time across both 400 and 600 MHz spectrometers was undertaken, with a considerable portion accessing specialised variable temperature measurements.

Congratulations Angus.

A full copy of Angus’ work can be found here.

James and Angus

Ash and Angus

Published on: 29 Sep 2021 1:19pm