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Studies factors influencing the bioavailability and disposition of drugs, and the application of this information to optimise the therapeutic usefulness of drugs in clinical practice. Particular emphasis is placed on the clinical role of the pharmacist and problem-solving in improving the use of drugs through the practical application of pharmacokinetics, although this information is also applicable to students not completing a pharmacy degree.

Topics include: formulation factors and therapeutic activity; route of administration and bioavailability; developments in drug delivery; estimating drug dosage requirements in clinical practice; therapeutic drug monitoring; drug interactions; an overview of sources of inter-patient variability in pharmacokinetics (eg extremes of age, renal disease, pharmacogenomics); clinical case studies and pharmacokinetics of specific drugs.

Unit objective: (i) to develop a good practical knowledge and understanding of drug absorption with various routes of administration and factors influencing absorption (biopharmaceutics) and (ii) to develop a foundation understanding of the processes of absorption, distribution, metabolism and excretion of drugs, and how these influence dosing regime design and individualisation of dosing (pharmacokinetics). The latter is subsequently studied in more detail in CSA414 Clinical Pharmacokinetics 4.

Summary 2020

Unit name Clinical Pharmacokinetics 3
Unit code CSA311
Credit points 12.5
Faculty/School College of Health and Medicine
School of Pharmacy and Pharmacology
Discipline Pharmacy

Dr Barbara Wimmer

Teaching staff

Dr Barbara Wimmer

Level Advanced
Available as student elective? No
Breadth Unit? No


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All Year 1 BPharm units plus CSA230 and CSA231.


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Teaching Pattern

Online learning resources (equivalent to 2 hours of activity per week) and1 x 2hr workshop weekly.

  • Written assignment (1000 words, 15%)
  • In-class tests (10%)
  • Mid-semester test (20%)
  • Exam (2 hr, 55%).

Note: To pass this unit, a student must score ≥ 50% in the exam, as well as achieving an aggregate overall mark of ≥ 50%.

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