Studies factors influencing the bioavailability and disposition of drugs, and the application of this information to optimise the therapeutic usefulness of drugs in clinical practice. Particular emphasis is placed on the clinical role of the pharmacist and problem-solving in improving the use of drugs through the practical application of pharmacokinetics, although this information is also applicable to students not completing a pharmacy degree.
Topics include: formulation factors and therapeutic activity; route of administration and bioavailability; developments in drug delivery; estimating drug dosage requirements in clinical practice; therapeutic drug monitoring; drug interactions; an overview of sources of inter-patient variability in pharmacokinetics (eg extremes of age, renal disease, pharmacogenomics); clinical case studies and pharmacokinetics of specific drugs.
Unit objective: (i) to develop a good practical knowledge and understanding of drug absorption with various routes of administration and factors influencing absorption (biopharmaceutics) and (ii) to develop a foundation understanding of the processes of absorption, distribution, metabolism and excretion of drugs, and how these influence dosing regime design and individualisation of dosing (pharmacokinetics). The latter is subsequently studied in more detail in CSA414 Clinical Pharmacokinetics 4.
|Unit name||Clinical Pharmacokinetics 3|
|Faculty/School||College of Health and Medicine
School of Pharmacy and Pharmacology
Dr Barbara Wimmer
Dr Barbara Wimmer
|Available as student elective?||No|
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|Band||Field of Education|
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All Year 1 BPharm units plus CSA230 and CSA231.
You cannot enrol in this unit as well as the following:
Online learning resources (equivalent to 2 hours of activity per week) and1 x 2hr workshop weekly.
Note: To pass this unit, a student must score ≥ 50% in the exam, as well as achieving an aggregate overall mark of ≥ 50%.
|Timetable||View the lecture timetable | View the full unit timetable|
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