Profiles

Alex Bissember

UTAS Home Associate Professor Alex Bissember

Alex Bissember

Associate Professor

Room 433 , Chemistry Building

03 6226 2158 (phone)

Alex.Bissember@utas.edu.au

Alex Bissember is an Associate Professor of Chemistry at the University of Tasmania.  His research interests span areas of organic, organometallic, inorganic, and natural products chemistry, and chemical education.

Biography

Alex received his BSc (Hons) from Australian National University in 2005, and completed his PhD with Professor Martin Banwell at the Australian National University in 2010. He was awarded the 2009 American Australian Association Merck Company Foundation Fellowship to support postdoctoral research with Professor Gregory Fu at the Massachusetts Institute of Technology and the California Institute of Technology. In 2013, Alex commenced his independent career at the University of Tasmania.

Career summary

Qualifications

DegreeThesis TitleUniversityCountryDate of Award
PhDNew Methods for the Synthesis of Heterocyclic CompoundsAustralian National UniversityAustralia22/02/2010
BSc (1st Class Hons)A New Approach to Annulated Isoquinolines Utilizing the Palladium-Catalyzed Ullmann Cross-Coupling ReactionAustralian National University Australia15/12/2005
BSc Australian National UniversityAustralia16/12/2004

Memberships

Professional practice

  • Royal Australian Chemical Society (RACI)
  • American Chemical Society (ACS)
  • Royal Society of Chemistry (RSC)
  • Australian Academy of Science Early- and Mid- Career Researcher (EMCR) Forum

Teaching

Organic Chemistry, Organometallic Chemistry, Catalysis

Teaching responsibility

  • KRA114 Chemistry 1B
  • KRA241 Chemistry 2A Organic and Inorganic Chemistry
  • KRA341 Organic and Bioorganic Chemistry

Research Appointments

  • 2015 Visiting Associate, California Institute of Technology
  • Editorial Board Member, Scientific Reports
  • RACI National Organic Division Treasurer
  • RACI Diversity and Inclusion Committee Member Chair (2019–2020)
  • RACI Organic Division Representative for Tasmania

View more on AssocProf Alex Bissember in WARP

Expertise

  • Organic Chemistry
  • Organometallic Chemistry
  • Inorganic Chemistry
  • Catalysis
  • Heterocyclic Chemistry
  • Natural Products Chemistry
  • Chemical Education

Research Themes

Alex’s research interests span organic, organometallic, inorganic, and natural products chemistry, and chemical education. A particular focus of his work seeks to employ transition metal-based catalysts to develop new chemical reactions and exploring new strategies for controlling external stimuli in organic synthesis. The unifying theme underpinning much of his research is the development of new chemical reactions and methodology by specifically departing from conventional approaches for the synthesis (or provenance) of important organic molecules.

Awards

  • 2020–2022 ARC Discovery Project Grant, DP200101714
  • 2020 Royal Australian Chemical Society Alan Sargeson Lectureship
  • 2019 Royal Society of Chemistry’s Dalton Transactions New Talent: Asia-Pacific
  • 2019 University of Tasmania Vice Chancellor’s Innovation Award
  • 2019 University of Tasmania College of Sciences & Engineering Innovation Award
  • 2018 University of Tasmania College of Sciences and Engineering Executive Dean’s Award for Development and Innovation in Learning and Teaching
  • 2017 Royal Australian Chemical Society  Organometallic Chemistry Award
  • 2017 Minister’s Tasmanian STEM Innovation of the Year Award
  • Finalist, 2017 Tasmanian STEM Young Researcher of the Year Award
  • 2017 University of Tasmania Vice Chancellor’s Award for Early Career Academic Teaching
  • 2017 Collier Charitable Fund Grant
  • 2016 University of Tasmania Citation for Outstanding Contributions to Student Learning
  • 2015 PhosAgro/ UNESCO/ IUPAC Green Chemistry for Life Grant
  • 2013 University of Tasmania Faculty of Science Engineering & Technology Early Career Researcher Award
  • 2009 American Australian Association Merck Company Foundation Fellowship

Current projects

Fields of Research

  • Organic Chemical Synthesis (030503)
  • Natural Products Chemistry (030502)
  • Transition Metal Chemistry (030207)
  • Separation Science (030108)
  • Science, Technology and Engineering Curriculum and Pedagogy (130212)
  • Organometallic Chemistry (039904)
  • Biologically Active Molecules (030401)
  • Inorganic Green Chemistry (030203)
  • Design Innovation (120302)
  • Medical Bacteriology (110801)
  • Chemical Sciences (039999)
  • Synthesis of Materials (030306)
  • f-Block Chemistry (030202)
  • Quantum Chemistry (030701)
  • Transport Properties and Non-Equilibrium Processes (030607)
  • Physical Chemistry of Materials (030304)
  • Polymerisation Mechanisms (030305)

Research Objectives

  • Expanding Knowledge in the Chemical Sciences (970103)
  • Human Pharmaceutical Treatments (e.g. Antibiotics) (860803)
  • Environmentally Sustainable Manufacturing (869899)
  • Syllabus and Curriculum Development (930302)
  • Clinical Health (Organs, Diseases and Abnormal Conditions) (920199)
  • Organic Industrial Chemicals (excl. Resins, Rubber and Plastics) (860604)
  • Physical and Chemical Conditions of Water in Fresh, Ground and Surface Water Environments (excl. Urban and Industrial Use) (961103)
  • Physical and Chemical Conditions of Water (961199)
  • Expanding Knowledge in the Biological Sciences (970106)

Publications

Total publications

65

Highlighted publications

(11 outputs)
YearTypeCitationAltmetrics
2019Journal ArticleNorcott PL, Hammill CL, Robertson JC, Olding A, Bissember AC, et al., 'TEMPO-Me: An electrochemically activated methylating agent', Journal of the American Chemical Society, 141 pp. 15450−15455. ISSN 0002-7863 (2019) [Refereed Article]

DOI: 10.1021/jacs.9b08634 [eCite] [Details]

Citations: Scopus - 3Web of Science - 5

Co-authors: Robertson JC; Olding A

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2019Journal ArticleRobertson JC, Coote ML, Bissember AC, 'Synthetic applications of light, electricity, mechanical force and flow', Nature Reviews: Chemistry, 3 pp. 290-304. ISSN 2397-3358 (2019) [Refereed Article]

DOI: 10.1038/s41570-019-0094-2 [eCite] [Details]

Citations: Scopus - 11

Co-authors: Robertson JC

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2018Journal ArticleNicholls TP, Robertson JC, Gardiner MG, Bissember AC, 'Identifying the potential of pulsed LED irradiation in synthesis: copper-photocatalysed C-F functionalisation', Chemical Communications, 54, (36) pp. 4589-4592. ISSN 1359-7345 (2018) [Refereed Article]

DOI: 10.1039/C8CC02244E [eCite] [Details]

Citations: Scopus - 13Web of Science - 12

Co-authors: Nicholls TP; Robertson JC; Gardiner MG

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2016Journal ArticleNicholls TP, Constable GE, Robertson JC, Gardiner MG, Bissember AC, 'Brønsted acid cocatalysis in copper(I)-photocatalyzed α-amino C−H bond functionalization', ACS Catalysis, 6, (1) pp. 451-457. ISSN 2155-5435 (2016) [Refereed Article]

DOI: 10.1021/acscatal.5b02014 [eCite] [Details]

Citations: Scopus - 53Web of Science - 49

Co-authors: Nicholls TP; Constable GE; Robertson JC; Gardiner MG

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2016Journal ArticleNicholls TP, Leonori D, Bissember AC, 'Applications of visible light photoredox catalysis to the synthesis of natural products and related compounds', Natural Product Reports, 33, (11) pp. 1248-1254. ISSN 0265-0568 (2016) [Contribution to Refereed Journal]

DOI: 10.1039/c6np00070c [eCite] [Details]

Citations: Scopus - 51Web of Science - 52

Co-authors: Nicholls TP

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2015Journal ArticleJust J, Deans BJ, Olivier WJ, Paull B, Bissember AC, et al., 'New method for the rapid extraction of natural products: efficient isolation of shikimic acid from star anise', Organic Letters, 17, (10) pp. 2428-2430. ISSN 1523-7060 (2015) [Refereed Article]

DOI: 10.1021/acs.orglett.5b00936 [eCite] [Details]

Citations: Scopus - 34Web of Science - 33

Co-authors: Just J; Deans BJ; Olivier WJ; Paull B; Smith JA

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2014Journal ArticleDo H-Q, Bachman S, Bissember AC, Peters JC, Fu GC, 'Photoinduced, copper-catalyzed alkylation of amides with unactivated secondary alkyl halides at room temperature', Journal of the American Chemical Society, 136, (5) pp. 2162-2167. ISSN 0002-7863 (2014) [Refereed Article]

DOI: 10.1021/ja4126609 [eCite] [Details]

Citations: Scopus - 112Web of Science - 108

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2013Journal ArticleBissember AC, Lundgren RJ, Creutz SE, Peters JC, Fu GC, 'Transition-metal-catalyzed alkylations of amines with alkyl halides: Photoinduced, copper-catalyzed couplings of carbazoles', Angewandte Chemie: International Edition, 52, (19) pp. 5129-5133. ISSN 1433-7851 (2013) [Refereed Article]

DOI: 10.1002/anie.201301202 [eCite] [Details]

Citations: Scopus - 111Web of Science - 109

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2013Journal ArticleZiegler DT, Choi J, Munoz-Molina JM, Bissember AC, Peters JC, et al., 'A versatile approach to Ullmann C-N couplings at room temperature: New families of nucleophiles and electrophiles for photoinduced, copper-catalyzed processes', Journal of the American Chemical Society, 135, (35) pp. 13107-13112. ISSN 0002-7863 (2013) [Refereed Article]

DOI: 10.1021/ja4060806 [eCite] [Details]

Citations: Scopus - 123Web of Science - 118

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2012Journal ArticleBissember AC, Levina A, Fu GC, 'A mild, palladium-catalyzed method for the dehydrohalogenation of alkyl bromides: Synthetic and mechanistic studies', Journal of the American Chemical Society, 134, (34) pp. 14232-14237. ISSN 0002-7863 (2012) [Refereed Article]

DOI: 10.1021/ja306323x [eCite] [Details]

Citations: Scopus - 65Web of Science - 66

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2009Journal ArticleMenon RS, Findlay AD, Bissember AC, Banwell MG, 'The Au(I)-catalyzed intramolecular hydroarylation of terminal alkynes under mild conditions: Application to the synthesis of 2H-chromenes, coumarins, benzofurans, and dihydroquinolines', The Journal of Organic Chemistry, 74, (13) pp. 8901-8903. ISSN 0022-3263 (2009) [Refereed Article]

DOI: 10.1021/jo902032p [eCite] [Details]

Citations: Scopus - 134Web of Science - 127

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Journal Article

(53 outputs)
YearCitationAltmetrics
2020Deans BJ, Just J, Tedone L, Kilah NL, Jordan GJ, et al., 'Distinct drimane chemotypes in Tasmanian Mountain Pepper (Tasmannia lanceolata): Differences in the profiles of pungent leaf phytochemicals associated with altitudinal cline', Journal of Agricultural and Food Chemistry, 68 pp. 315−322. ISSN 1520-5118 (2020) [Refereed Article]

DOI: 10.1021/acs.jafc.9b05703 [eCite] [Details]

Co-authors: Deans BJ; Just J; Tedone L; Kilah NL; Jordan GJ; Smith JA

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2020Quirino JP, Maya Alejandro F, Bissember AC, 'Towards cleaner downstream processing of biomass waste chemical products by liquid chromatography: A review and recommendations', Journal of Cleaner Production, 253 Article 119937. ISSN 0959-6526 (2020) [Refereed Article]

DOI: 10.1016/j.jclepro.2019.119937 [eCite] [Details]

Co-authors: Quirino JP; Maya Alejandro F

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2019Ho CC, Ariafard A, Hyland CJT, Bissember AC, 'Phosphine-scavenging cationic gold(I) complexes: alternative applications of gold cocatalysis in fundamental palladium-catalyzed cross-couplings', Organometallics, 38, (13) pp. 2683-2688. ISSN 0276-7333 (2019) [Refereed Article]

DOI: 10.1021/acs.organomet.9b00294 [eCite] [Details]

Co-authors: Ho CC; Ariafard A

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2019Nicholls TP, Bissember AC, 'Developments in visible-light-mediated copper photocatalysis', Tetrahedron Letters, 60, (32) Article 150883. ISSN 0040-4039 (2019) [Refereed Article]

DOI: 10.1016/j.tetlet.2019.06.042 [eCite] [Details]

Citations: Scopus - 1Web of Science - 1

Co-authors: Nicholls TP

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2019Nicholls TP, Burt LK, Simpson PV, Massi M, Bissember AC, 'Tricarbonyl rhenium(I) tetrazolato and N-heterocyclic carbene complexes: versatile visible-light-mediated photoredox catalysts', Dalton Transactions, 48, (33) pp. 12749-12754. ISSN 1477-9226 (2019) [Refereed Article]

DOI: 10.1039/C9DT02533B [eCite] [Details]

Citations: Web of Science - 2

Co-authors: Nicholls TP; Burt LK

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2019Nicholls TP, Caporale C, Massi M, Gardiner MG, Bissember AC, 'Synthesis and characterisation of homoleptic 2,9- diaryl-1,10-phenanthroline copper(I) complexes: influencing selectivity in photoredox-catalysed atom-transfer radical addition reactions', Dalton Transactions, 48 pp. 7920-7301. ISSN 1477-9226 (2019) [Refereed Article]

DOI: 10.1039/c8dt04116d [eCite] [Details]

Citations: Scopus - 6Web of Science - 6

Co-authors: Nicholls TP; Gardiner MG

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2019Norcott PL, Hammill CL, Robertson JC, Olding A, Bissember AC, et al., 'TEMPO-Me: An electrochemically activated methylating agent', Journal of the American Chemical Society, 141 pp. 15450−15455. ISSN 0002-7863 (2019) [Refereed Article]

DOI: 10.1021/jacs.9b08634 [eCite] [Details]

Citations: Scopus - 3Web of Science - 5

Co-authors: Robertson JC; Olding A

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2019Ranieri AM, Burt LK, Stagni S, Zacchini S, Skelton BW, et al., 'Anionic cyclometalated platinum(II) tetrazolato complexes as viable photoredox catalysts', Organometallics, 38, (5) pp. 1108-1117. ISSN 0276-7333 (2019) [Refereed Article]

DOI: 10.1021/acs.organomet.8b00913 [eCite] [Details]

Citations: Scopus - 5Web of Science - 5

Co-authors: Burt LK

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2019Robertson JC, Coote ML, Bissember AC, 'Synthetic applications of light, electricity, mechanical force and flow', Nature Reviews: Chemistry, 3 pp. 290-304. ISSN 2397-3358 (2019) [Refereed Article]

DOI: 10.1038/s41570-019-0094-2 [eCite] [Details]

Citations: Scopus - 11

Co-authors: Robertson JC

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2019Turner DN, Just J, Dasari R, Smith JA, Bissember AC, et al., 'Activity of natural and synthetic polygodial derivatives against Trypanosoma cruzi amastigotes, trypomastigotes and epimastigotes', Natural Product Research pp. 1-4. ISSN 1478-6419 (2019) [Refereed Article]

DOI: 10.1080/14786419.2019.1597350 [eCite] [Details]

Co-authors: Just J; Smith JA

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2019Woolley KL, Nadikudi M, Koupaei MN, Corban M, McCartney P, et al., 'Amide linked redox-active naphthoquinones for the treatment of mitochondrial dysfunction', MedChemComm, 10, (3) pp. 399-412. ISSN 2040-2511 (2019) [Refereed Article]

DOI: 10.1039/c8md00582f [eCite] [Details]

Citations: Scopus - 2Web of Science - 2

Co-authors: Woolley KL; Nadikudi M; Corban M; Lewis TW; Gueven N; Smith JA

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2018Bissember AC, Gardiner MG, Wierenga TS, 'α-Cyanocarbanion complexes and their application in synthesis', Journal of Organometallic Chemistry, 869 pp. 213-226. ISSN 0022-328X (2018) [Refereed Article]

DOI: 10.1016/j.jorganchem.2018.04.010 [eCite] [Details]

Citations: Scopus - 3Web of Science - 3

Co-authors: Gardiner MG; Wierenga TS

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2018De La Chapa J, Singha PK, Sallaway M, Self K, Nasreldin R, et al., 'Novel polygodial analogs P3 and P27: Efficacious therapeutic agents disrupting mitochondrial function in oral squamous cell carcinoma', International Journal of Oncology, 53, (6) pp. 2627-2636. ISSN 1019-6439 (2018) [Refereed Article]

DOI: 10.3892/ijo.2018.4585 [eCite] [Details]

Citations: Scopus - 1Web of Science - 2

Co-authors: Just J; Smith JA

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2018Deans BJ, Kilah NL, Jordan GJ, Bissember AC, Smith JA, 'Arbutin derivatives isolated from ancient proteaceae: potential phytochemical markers present in Bellendena, Cenarrhenes, and Persoonia Genera', Journal of Natural Products, 81, (5) pp. 1241-1251. ISSN 0163-3864 (2018) [Refereed Article]

DOI: 10.1021/acs.jnatprod.7b01038 [eCite] [Details]

Citations: Scopus - 8Web of Science - 8

Co-authors: Deans BJ; Kilah NL; Jordan GJ; Smith JA

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2018Deans BJ, Olivier WJ, Girbino D, Bissember AC, Smith JA, 'Extraction of carboxylic acid-containing diterpenoids from Dodonaea viscosa via pressurised hot water extraction', Fitoterapia, 126 pp. 65-68. ISSN 0367-326X (2018) [Refereed Article]

DOI: 10.1016/j.fitote.2017.10.008 [eCite] [Details]

Citations: Scopus - 5Web of Science - 5

Co-authors: Deans BJ; Olivier WJ; Smith JA

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2018Deans BJ, Skierka BE, Karagiannakis BW, Vuong D, Lacey E, et al., 'Siliquapyranone: a tannic acid Tetrahydropyran-2-one isolated from the leaves of carob (Ceratonia siliqua) by pressurised hot water extraction', Australian Journal of Chemistry, 71, (9) pp. 702-707. ISSN 0004-9425 (2018) [Refereed Article]

DOI: 10.1071/CH18265 [eCite] [Details]

Citations: Scopus - 4Web of Science - 4

Co-authors: Deans BJ; Skierka BE; Smith JA

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2018Deans BJ, Tedone L, Bissember AC, Smith JA, 'Phytochemical profile of the rare, ancient clone Lomatia tasmanica and comparison to other endemic Tasmanian species L. tinctoria and L. polymorpha', Phytochemistry, 153 pp. 74-78. ISSN 0031-9422 (2018) [Refereed Article]

DOI: 10.1016/j.phytochem.2018.05.019 [eCite] [Details]

Citations: Scopus - 5Web of Science - 5

Co-authors: Deans BJ; Tedone L; Smith JA

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2018Deans BJ, de Salas M, SMith JA, Bissember AC, 'Natural products isolated from endemic Tasmanian vascular plants', Australian Journal of Chemistry, 71, (10) pp. 756-767. ISSN 0004-9425 (2018) [Refereed Article]

DOI: 10.1071/CH18283 [eCite] [Details]

Citations: Scopus - 1Web of Science - 1

Co-authors: Deans BJ; de Salas M; SMith JA

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2018Ho CC, Deans BJ, Just J, Warr GG, Wilkinson S, et al., 'Employing pressurized hot water extraction (PHWE) to explore natural products chemistry in the undergraduate laboratory', Journal of Visualized Experiments, 141 Article e58195. ISSN 1940-087X (2018) [Refereed Article]

DOI: 10.3791/58195 [eCite] [Details]

Co-authors: Ho CC; Deans BJ; Just J; Smith JA

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2018Ho CC, Olding A, Smith JA, Bissember AC, 'Nuances in fundamental Suzuki−Miyaura cross-couplings employing [Pd(PPh3)4]: poor reactivity of aryl Iodides at lower temperatures', Organometallics, 37, (11) pp. 1745-1750. ISSN 0276-7333 (2018) [Refereed Article]

DOI: 10.1021/acs.organomet.8b00189 [eCite] [Details]

Citations: Scopus - 6Web of Science - 6

Co-authors: Ho CC; Olding A; Smith JA

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2018Hyland IK, O'Toole RF, Smith JA, Bissember AC, 'Progress in the development of Platelet-Activating Factor Receptor (PAFr) antagonists and applications in the treatment of inflammatory diseases', ChemMedChem, 13, (18) pp. 1873-1884. ISSN 1860-7179 (2018) [Refereed Article]

DOI: 10.1002/cmdc.201800401 [eCite] [Details]

Citations: Scopus - 6Web of Science - 5

Co-authors: Hyland IK; O'Toole RF; Smith JA

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2018Leow MY, Ho CC, Gardiner MG, Bissember AC, 'Non-classical anionic naked N-heterocyclic carbenes: fundamental properties and emerging applications in synthesis and catalysis', Catalysts, 8, (12) Article 620. ISSN 2073-4344 (2018) [Refereed Article]

DOI: 10.3390/catal8120620 [eCite] [Details]

Citations: Scopus - 4Web of Science - 4

Co-authors: Leow MY; Ho CC; Gardiner MG

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2018Nicholls TP, Robertson JC, Gardiner MG, Bissember AC, 'Identifying the potential of pulsed LED irradiation in synthesis: copper-photocatalysed C-F functionalisation', Chemical Communications, 54, (36) pp. 4589-4592. ISSN 1359-7345 (2018) [Refereed Article]

DOI: 10.1039/C8CC02244E [eCite] [Details]

Citations: Scopus - 13Web of Science - 12

Co-authors: Nicholls TP; Robertson JC; Gardiner MG

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2018Olding A, Nicholls TP, Bissember AC, 'Recent applications of [Cu(dap)2]Cl in visible light-mediated photoredox catalysis', Australian Journal of Chemistry, 71, (7) pp. 547-548. ISSN 0004-9425 (2018) [Contribution to Refereed Journal]

DOI: 10.1071/CH18046 [eCite] [Details]

Citations: Scopus - 3Web of Science - 3

Co-authors: Olding A; Nicholls TP

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2018Olivier WJ, Gardiner MG, Bissember AC, Smith JA, 'Brønsted acid-mediated annulations of pyrroles featuring N-tethered α,β-unsaturated ketones and esters: total syntheses of (±)-tashiromine and (±)-indolizidine 209I', Tetrahedron, 74, (38) pp. 5436-5441. ISSN 0040-4020 (2018) [Refereed Article]

DOI: 10.1016/j.tet.2018.04.067 [eCite] [Details]

Citations: Scopus - 2Web of Science - 1

Co-authors: Olivier WJ; Gardiner MG; Smith JA

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2018Olivier WJ, Smith JA, Bissember AC, 'Methods for the synthesis of annulated pyrroles via cyclisation strategies', Organic and Biomolecular Chemistry, 16, (8) pp. 1216-1226. ISSN 1477-0520 (2018) [Refereed Article]

DOI: 10.1039/C7OB03144K [eCite] [Details]

Citations: Scopus - 20Web of Science - 17

Co-authors: Olivier WJ; Smith JA

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2018Pullen R, Olding A, SMith JA, Bissember AC, 'Capstone laboratory experiment investigating key features of palladium-catalyzed Suzuki-Miyaura cross-coupling reactions', Journal of Chemical Education pp. 1-5. ISSN 0021-9584 (2018) [Refereed Article]

DOI: 10.1021/acs.jchemed.7b00964 [eCite] [Details]

Citations: Scopus - 5Web of Science - 6

Co-authors: Pullen R; Olding A; SMith JA

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2018Pullen R, Thickett SC, Bissember AC, 'Investigating the viability of a competency-based, qualitative laboratory assessment model in first-year undergraduate chemistry', Chemistry Education Research and Practice, 19 pp. 629-637. ISSN 1756-1108 (2018) [Refereed Article]

DOI: 10.1039/C7RP00249A [eCite] [Details]

Citations: Web of Science - 2

Co-authors: Pullen R; Thickett SC

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2018Qian D, Chen M, Bissember AC, Sun J, 'Counterion-induced asymmetric control in ring-opening of azetidiniums: facile access to chiral amines', Angewandte Chemie International Edition, 57, (14) pp. 3763-3766. ISSN 1433-7851 (2018) [Refereed Article]

DOI: 10.1002/anie.201712395 [eCite] [Details]

Citations: Scopus - 15Web of Science - 14

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2018Rihak KJ, Bissember AC, Smith JA, 'Polygodial: a viable natural product scaffold for the rapid synthesis of novel polycyclic pyrrole and pyrrolidine derivatives', Tetrahedron, 74, (12) pp. 1167-1174. ISSN 0040-4020 (2018) [Refereed Article]

DOI: 10.1016/j.tet.2017.10.015 [eCite] [Details]

Citations: Scopus - 6Web of Science - 5

Co-authors: Rihak KJ; Smith JA

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2017Deans BJ, Just J, Chhetri J, Burt LK, Smith JN, et al., 'Pressurized hot water extraction as a viable bioprospecting tool: isolation of coumarin natural products from previously unexamined Correa (Rutaceae) species', ChemistrySelect, 2, (8) pp. 2439-2443. ISSN 2365-6549 (2017) [Refereed Article]

DOI: 10.1002/slct.201602006 [eCite] [Details]

Citations: Scopus - 9Web of Science - 9

Co-authors: Deans BJ; Just J; Chhetri J; Burt LK; Smith JN; Kilah NL; Guven N; Smith JA

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2016Deans BJ, Bissember AC, Smith JA, 'Practical Isolation of Asperuloside from Coprosma quadrifida via Rapid Pressurised Hot Water Extraction', Australian Journal of Chemistry, 69, (11) pp. 1219-1222. ISSN 0004-9425 (2016) [Refereed Article]

DOI: 10.1071/CH15743 [eCite] [Details]

Citations: Scopus - 10Web of Science - 10

Co-authors: Deans BJ; Smith JA

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2016Howard JK, Rihak KJ, Bissember AC, Smith JA, 'The oxidation of pyrrole', Chemistry - An Asian Journal, 11, (2) pp. 155-167. ISSN 1861-4728 (2016) [Refereed Article]

DOI: 10.1002/asia.201500659 [eCite] [Details]

Citations: Scopus - 21Web of Science - 22

Co-authors: Howard JK; Rihak KJ; Smith JA

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2016Howard JK, Rihak KJ, Hyland CJT, Bissember AC, Smith JA, 'Visible light dye-photosensitised oxidation of pyrroles using a simple LED photoreactor', Organic and Biomolecular Chemistry, 14, (37) pp. 8873-8880. ISSN 1477-0520 (2016) [Refereed Article]

DOI: 10.1039/c6ob01719c [eCite] [Details]

Citations: Scopus - 4Web of Science - 4

Co-authors: Howard JK; Rihak KJ; Hyland CJT; Smith JA

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2016Just J, Bunton GL, Deans BJ, Murray NL, Bissember AC, et al., 'Extraction of Eugenol from Cloves Using an Unmodified Household Espresso Machine: An Alternative to Traditional Steam-Distillation', Journal of Chemical Education, 93, (1) pp. 213-216. ISSN 0021-9584 (2016) [Refereed Article]

DOI: 10.1021/acs.jchemed.5b00476 [eCite] [Details]

Citations: Scopus - 20Web of Science - 22

Co-authors: Just J; Bunton GL; Deans BJ; Smith JA

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2016Nicholls TP, Constable GE, Robertson JC, Gardiner MG, Bissember AC, 'Brønsted acid cocatalysis in copper(I)-photocatalyzed α-amino C−H bond functionalization', ACS Catalysis, 6, (1) pp. 451-457. ISSN 2155-5435 (2016) [Refereed Article]

DOI: 10.1021/acscatal.5b02014 [eCite] [Details]

Citations: Scopus - 53Web of Science - 49

Co-authors: Nicholls TP; Constable GE; Robertson JC; Gardiner MG

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2016Nicholls TP, Leonori D, Bissember AC, 'Applications of visible light photoredox catalysis to the synthesis of natural products and related compounds', Natural Product Reports, 33, (11) pp. 1248-1254. ISSN 0265-0568 (2016) [Contribution to Refereed Journal]

DOI: 10.1039/c6np00070c [eCite] [Details]

Citations: Scopus - 51Web of Science - 52

Co-authors: Nicholls TP

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2016Olivier WJ, Kilah NL, Horne J, Bissember AC, Smith JA, 'ent-Labdane Diterpenoids from Dodonaea viscosa', Journal of Natural Products, 79, (12) pp. 3117-3126. ISSN 0163-3864 (2016) [Refereed Article]

DOI: 10.1021/acs.jnatprod.6b00858 [eCite] [Details]

Citations: Scopus - 5Web of Science - 6

Co-authors: Olivier WJ; Kilah NL; Horne J; Smith JA

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2015Abel S-AG, Olivier WJ, Pederson RL, Bissember AC, Smith JA, 'Complete stereocontrol in the synthesis of harmonine and novel analogues facilitated by a Grubbs Z-selective cross-metathesis catalysis', Australian Journal of Chemistry, 68, (12) pp. 1815-1820. ISSN 0004-9425 (2015) [Refereed Article]

DOI: 10.1071/CH15397 [eCite] [Details]

Citations: Scopus - 3Web of Science - 1

Co-authors: Abel S-AG; Olivier WJ; Smith JA

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2015Just J, Deans BJ, Olivier WJ, Paull B, Bissember AC, et al., 'New method for the rapid extraction of natural products: efficient isolation of shikimic acid from star anise', Organic Letters, 17, (10) pp. 2428-2430. ISSN 1523-7060 (2015) [Refereed Article]

DOI: 10.1021/acs.orglett.5b00936 [eCite] [Details]

Citations: Scopus - 34Web of Science - 33

Co-authors: Just J; Deans BJ; Olivier WJ; Paull B; Smith JA

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2015Just J, Jordan TB, Paull B, Bissember AC, Smith JA, 'Practical isolation of polygodial from Tasmannia lanceolata: a viable scaffold for synthesis', Organic and Biomolecular Chemistry, 13, (46) pp. 11200-11207. ISSN 1477-0520 (2015) [Refereed Article]

DOI: 10.1039/c5ob01573a [eCite] [Details]

Citations: Scopus - 25Web of Science - 25

Co-authors: Just J; Jordan TB; Paull B; Smith JA

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2015Nicholls TP, Henderson LC, Bissember AC, 'Brønsted acid-mediated radical processes in organic synthesis', Australian Journal of Chemistry, 68, (12) pp. 1791-1795. ISSN 0004-9425 (2015) [Refereed Article]

DOI: 10.1071/CH15389 [eCite] [Details]

Citations: Scopus - 3Web of Science - 3

Co-authors: Nicholls TP

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2014Do H-Q, Bachman S, Bissember AC, Peters JC, Fu GC, 'Photoinduced, copper-catalyzed alkylation of amides with unactivated secondary alkyl halides at room temperature', Journal of the American Chemical Society, 136, (5) pp. 2162-2167. ISSN 0002-7863 (2014) [Refereed Article]

DOI: 10.1021/ja4126609 [eCite] [Details]

Citations: Scopus - 112Web of Science - 108

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2013Bissember AC, 'Methyl cyanoformate (Mander's reagent)', Synlett, 2009, (4) pp. 681-682. ISSN 0936-5214 (2013) [Contribution to Refereed Journal]

DOI: 10.1055/s-0028-1087716 [eCite] [Details]

Citations: Scopus - 2Web of Science - 1

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2013Bissember AC, Lundgren RJ, Creutz SE, Peters JC, Fu GC, 'Transition-metal-catalyzed alkylations of amines with alkyl halides: Photoinduced, copper-catalyzed couplings of carbazoles', Angewandte Chemie: International Edition, 52, (19) pp. 5129-5133. ISSN 1433-7851 (2013) [Refereed Article]

DOI: 10.1002/anie.201301202 [eCite] [Details]

Citations: Scopus - 111Web of Science - 109

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2013Ziegler DT, Choi J, Munoz-Molina JM, Bissember AC, Peters JC, et al., 'A versatile approach to Ullmann C-N couplings at room temperature: New families of nucleophiles and electrophiles for photoinduced, copper-catalyzed processes', Journal of the American Chemical Society, 135, (35) pp. 13107-13112. ISSN 0002-7863 (2013) [Refereed Article]

DOI: 10.1021/ja4060806 [eCite] [Details]

Citations: Scopus - 123Web of Science - 118

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2012Bissember AC, Levina A, Fu GC, 'A mild, palladium-catalyzed method for the dehydrohalogenation of alkyl bromides: Synthetic and mechanistic studies', Journal of the American Chemical Society, 134, (34) pp. 14232-14237. ISSN 0002-7863 (2012) [Refereed Article]

DOI: 10.1021/ja306323x [eCite] [Details]

Citations: Scopus - 65Web of Science - 66

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2011Lange J, Bissember AC, Banwell MG, Cade IA, 'Synthesis of 2,3-dihydro-4(1H)-quinolones and the corresponding 4(1H)-quinolones via low-temperature fries rearrangement of N-arylazetidin-2-ones', Australian Journal of Chemistry, 64, (4) pp. 454-470. ISSN 0004-9425 (2011) [Refereed Article]

DOI: 10.1071/CH10465 [eCite] [Details]

Citations: Scopus - 16Web of Science - 15

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2009Bissember AC, Banwell MG, 'Preparation of some angularly substituted and highly functionalized quinolizidines as building blocks for the synthesis of various alkaloids and related scaffolds of medicinal interest', Tetrahedron, 65, (39) pp. 8222-8230. ISSN 0040-4020 (2009) [Refereed Article]

DOI: 10.1016/j.tet.2009.07.067 [eCite] [Details]

Citations: Scopus - 6Web of Science - 4

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2009Bissember AC, Banwell MG, 'Microwave-assisted trans-halogenation reactions of various chloro-, bromo-, trifluoromethanesulfonyloxy- and nonafluorobutanesulfonyloxy-substituted quinolines, isoquinolines, and pyridines leading to the corresponding iodinated heterocycles', The Journal of Organic Chemistry, 74, (13) pp. 4893-4895. ISSN 0022-3263 (2009) [Refereed Article]

DOI: 10.1021/jo9008386 [eCite] [Details]

Citations: Scopus - 18Web of Science - 17

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2009Menon RS, Findlay AD, Bissember AC, Banwell MG, 'The Au(I)-catalyzed intramolecular hydroarylation of terminal alkynes under mild conditions: Application to the synthesis of 2H-chromenes, coumarins, benzofurans, and dihydroquinolines', The Journal of Organic Chemistry, 74, (13) pp. 8901-8903. ISSN 0022-3263 (2009) [Refereed Article]

DOI: 10.1021/jo902032p [eCite] [Details]

Citations: Scopus - 134Web of Science - 127

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2008Bissember AC, Banwell MG, '4-iodo-6-methoxyquinoline', Organic Preparations and Procedures International, 40, (6) pp. 557-589. ISSN 0030-4948 (2008) [Refereed Article]

DOI: 10.1080/00304940809458120 [eCite] [Details]

Citations: Scopus - 1Web of Science - 1

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2007Bissember AC, Phillis AT, Banwell MG, Willis AC, 'Base-promoted reactions of dichlorocarbene adducts of cyclic enamines: A new route to annulated pyrroles', Organic Letters, 9, (26) pp. 5421-5424. ISSN 1523-7060 (2007) [Refereed Article]

DOI: 10.1021/ol7021774 [eCite] [Details]

Citations: Scopus - 11Web of Science - 11

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Chapter in Book

(6 outputs)
YearCitationAltmetrics
2020Meyer AG, Bissember AC, Hyland CJT, Williams CC, Szabo M, et al., 'Seven-Membered Rings', Progress in Heterocyclic Chemistry, Elsevier, GW Gribble, JA Joule (ed), Netherlands, pp. 597-647. ISBN 978-0-12-819962-6 (2020) [Research Book Chapter]

DOI: 10.1016/B978-0-12-819962-6.00016-6 [eCite] [Details]

Co-authors: Hyland IK; Olivier WJ

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2018Meyer AG, Bissember AC, Hyland CJT, Williams CC, Szabo M, et al., 'Seven-Membered Rings', Progress in Heterocyclic Chemistry, Elsevier Science Bv, GW Gribble & JA Joule (ed), Amsterdam, Netherlands, pp. 493-550. ISBN 978-0-08-102788-2 (2018) [Research Book Chapter]

DOI: 10.1016/B978-0-08-102788-2.00016-7 [eCite] [Details]

Citations: Scopus - 6

Co-authors: Abel S-AG; Hyland IK

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2017Meyer AG, Bissember AC, Hyland C, Smith JA, Williams CC, et al., 'Chapter 7: Seven-Membered Rings', Progress in Heterocyclic Chemistry, Elsevier Ltd., GW Gribble, JA Joule (ed), Netherlands, pp. 579-633. ISBN 9780081023105 (2017) [Research Book Chapter]

DOI: 10.1016/B978-0-08-102310-5.00016-3 [eCite] [Details]

Citations: Scopus - 4

Co-authors: Smith JA; Abel SAG

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2016Meyer AG, Smith JA, Hyland C, Williams CC, Bissember AC, et al., 'Seven-Membered Rings', Progress in Heterocyclic Chemistry, Elsevier, GW Gribble & JA Joule (ed), Amsterdam, Netherlands, pp. 579-622. ISBN 9780081007556 (2016) [Research Book Chapter]

DOI: 10.1016/B978-0-08-100755-6.00016-8 [eCite] [Details]

Citations: Scopus - 4

Co-authors: Smith JA; Nicholls TP

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2015Ryan JH, Smith JA, Hyland C, Meyer AG, Williams CC, et al., 'Seven-Membered Rings', Progress in Heterocyclic Chemistry, Elsevier, GW Gribble, JA Joule (ed), Amsterdam, The Netherlands, pp. 531-573. ISBN 978-0-08-100024-3 (2015) [Research Book Chapter]

DOI: 10.1016/B978-0-08-100024-3.00016-7 [eCite] [Details]

Citations: Scopus - 7

Co-authors: Smith JA; Just J

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2014Ryan JH, Smith JA, Hyland C, Meyer AG, Williams CC, et al., 'Seven-Membered Rings', Progress in Heterocyclic Chemistry, Elsevier, GW Gribble, JA Joule (ed), Amsterdam, The Netherlands, pp. 521-571. ISBN 978-0-08-100017-5 (2014) [Research Book Chapter]

DOI: 10.1016/B978-0-08-100017-5.00016-9 [eCite] [Details]

Citations: Scopus - 4

Co-authors: Smith JA; Just J

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Conference Publication

(1 outputs)
YearCitationAltmetrics
2018Bissember A, Hindrum S, Hornblow M, Kilah N, Power J, et al., 'Growing and bio-fabricating SCOBY: a project developed in an extended cross-disciplinary research team', Proceedings of the 1st Annual Design Research Conference (ADR18), 27-28 September 2018, University of Sydney, pp. 581-595. ISBN 978-0-646-99249-5 (2018) [Refereed Conference Paper]

[eCite] [Details]

Co-authors: Hindrum S; Hornblow M; Kilah N; Power J; Thickett S; Yong A

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Other Public Output

(5 outputs)
YearCitationAltmetrics
2019Schultz M, Coote M, Bissember A, 'RACI inclusion and diversity: a report on progress', Chemistry in Australia, Royal Australian Chemical Institute, Australia, May/June, pp. 22-25. (2019) [Magazine Article]

[eCite] [Details]

2018Desire CT, Deans R, Shellie RA, Smith JA, Bissember AC, 'Oranges, lemons and limonene: addressing surprisingly persistent and enduring myths', Chemistry in Australia, Royal Australian Chemical Institute, Australia, February 2018, p. 35. (2018) [Magazine Article]

[eCite] [Details]

Co-authors: Desire CT; Deans R; Shellie RA; Smith JA

2018Pullen R, Thickett SC, Bissember AC, 'Assessment in the chemistry teaching laboratory', Chemistry in Australia, The Royal Australian Chemical Institute, Melbourne, Australia, Nov/Dec 2018, pp. 24-27. (2018) [Magazine Article]

[eCite] [Details]

Co-authors: Pullen R; Thickett SC

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2018Pullen R, Thickett SC, Bissember AC, 'Assessment in the chemistry teaching laboratory', Chemistry in Australia, Royal Australian Chemical Institute, Australia, November/December, pp. 24-27. (2018) [Magazine Article]

[eCite] [Details]

Co-authors: Thickett SC

2017Bissember A, 'Green chemistry is key to reducing waste and improving sustainablity', The Conversation, The Conversation Media Group Ltd, Australia, 27 March (2017) [Magazine Article]

[eCite] [Details]

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Grants & Funding

Funding Summary

Number of grants

8

Total funding

$833,427

Projects

Metal complexes for sustainable light-driven synthesis (2020 - 2022)$360,000
Description
The aim of this project is to use cheap, earth-abundant transition metal ions and visible light to drive multi-electron transfer processes for challenging synthetic reactions. The significance of this problem is that these reactions are typically performed using expensive precious metals, which is not sustainable or suitable for large scale industrial applications. The outcome will be new knowledge and sustainable technologies for harnessing visible light for synthetic chemistry applications. The benefit will be the efficient and cost-effective use of visible light for synthesis using cheap earth-abundant metal ions.
Funding
Australian Research Council ($360,000)
Scheme
Grant-Discovery Projects
Administered By
University of New South Wales
Research Team
Beves J; Moore E; Bissember AC
Period
2020 - 2022
Grant Reference
DP200101714
Ecodetection improvements (2019 - 2020)$269,487
Description
Develop new chemistry for ecodetection applications of (1) glyphosate, (2) mining ions (cyanide, etc), and (3) heavy metals.
Funding
Eco Detection Australia Pty Ltd ($269,487)
Scheme
Contract Research
Administered By
University of Tasmania
Research Team
Breadmore MC; Bissember AC; Amuno R
Period
2019 - 2020
Isolation and synthesis of potential new therapeutic agents from Hemp (Cannabis sativa) and their biological evaluation (2018 - 2021)$105,000
Description
Cannabis and cannabis extracts have been reported to have beneficial applications to many indications including the management of seizures, pain, cancer and appetite amongst others. One problem has been the illicit nature of the material which results in lack of control of the dose and chemical profile of material which can be due to different plant varieties, growing conditions, extraction preparation and mode of delivery. This project aims to adopt a drug discovery approach to provide solid evidence for the effect of different cannabinoids by isolating the individual components for thorough evaluation of any therapeutical applications. In this way, clear dose dependant activity can be studied and protocols for the prescription of cannabinoids can be developed that are in-line with modern pharmaceutical procedures. This will also be the start point for the development of novel semi-synthetic cannabinoids that will allow us to develop structure activity relationships for different indications. This potentially extends the scope of the medicinal cannabis industry to be a raw material for the synthesis of active non-natural derivates similar to the semi-synthetic opiates.
Funding
Martha Jane Medical ($105,000)
Scheme
Contract Research
Administered By
University of Tasmania
Research Team
Smith JA; Jacobson GA; Guven N; Bissember AC
Period
2018 - 2021
Artificial Photosynthesis: Using Light to Sustainably Prepare Valuable Chemical Compounds (2018)$30,007
Description
This work is concerned with the development of new visible light copper photocatalysts and their applications to small molecule activation, organic synthesis, and green chemistry
Funding
Collier Charitable Fund ($30,007)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Bissember AC
Year
2018
Extraction and analysis of Plant Material (2016)$3,000
Description
Extraction of plant root and analysis of compounds. Root to be extracted using pressurised hot water extraction and the major components purified by flash chromatography and characterised.
Funding
ZoeticDevelopment Group Pty Ltd ($3,000)
Scheme
Consultancy
Administered By
University of Tasmania
Research Team
Smith JA; Bissember AC
Year
2016
Synthesis of Opiate Derivatives (2015)$20,000
Funding
Tasmanian Alkaloids Pty Ltd ($20,000)
Scheme
Contract Research
Administered By
University of Tasmania
Research Team
Smith JA; Bissember AC
Year
2015
Development of new viable and inexpensive visible light copper photocatalysts (2015)$31,433
Description
This project is concerned with the preparation of a range of copper-based visible light photocatalysts coupled with an investigation of their application in organic synthesis. The immediate aims are to demonstrate that these complexes represent viable alternatives to established metal-based photocatalysts that rely on the reactivity of expensive and toxic third-row transition metals.
Funding
United Nations Educational, Scientific & Cultural Organization ($31,433)
Scheme
Grant-Green Chemistry for Young Scientists
Administered By
University of Tasmania
Research Team
Bissember AC
Year
2015
Development of novel transition metal-catalyzed processes: Cascade and photochemical reactions (2014)$14,500
Funding
University of Tasmania ($14,500)
Scheme
Grant-Research Enhancement (REGS)
Administered By
University of Tasmania
Research Team
Bissember AC
Year
2014

Research Supervision

As a teacher/ scholar, I am particularly committed to better integrating teaching and research in chemistry and my research (and teaching) practice expressly aims to improve this situation. As part of this, I strive to integrate undergraduates into my research group and increase their participation in research more generally. I am the University of Tasmania Chemistry Undergraduate Research Coordinator.

Current

10

Completed

10

Current

DegreeTitleCommenced
PhDSynthesis and Functionalisation of Heterocyclic Molecules with Bioactive Properties2016
PhDDevelopment of New Stereoselective Transition Metal-catalysed Reactions2017
PhDEfficient Synthesis of Complex Molecules2017
PhDNatural Deep Eutectic Solvents for Polymer Colloid Synthesis2018
PhDInvestigating the Synthetic Applications of Novel Transition Metal-Based Catalysts2018
PhDDevelopment and Optimization of Transition Metal-based Catalytic Reactions2018
PhDIsolation and Synthesis of Potential New Therapeutic Agents from Hemp (Cannabis sativa) and their Biological Evaluation2019
MastersNatural Products Chemistry: investigating molecules with therapeutic potential and chemotaxonomic value, molecules found in the endemic plant species of Tasmania2019
PhDIsolation of Plant Secondary Metabolites of Taxonomic and Therapeutic Significance2020
PhDBioprospecting for Bioactive Compounds: Exploiting natures medicine chest2020

Completed

DegreeTitleCompleted
PhDApplications of Density Functional Theory (DFT) in Organic and Inorganic Reactions
Candidate: Ali Gouranourimi
2020
PhDSynthetic Approaches to Naturally Occurring Strigolactones and Selected Analogues
Candidate: Steven Alan Grant Abel
2020
PhDIsolation of Plant Natural Products of Potential Chemotaxonomic Significance and Medicinal Value
Candidate: Bianca Judith Deans
2019
PhDTowards the Isolation of a-N-Metallated Free N-Heterocyclic Carbenes
Candidate: Mei Yi Leow
2019
PhDN-Heterocyclic Carbene-Based Pd and Ni Complexes and their Applications to the Activation of Alkylnitriles
Candidate: Tanita Shivon Wierenga
2019
PhDExpanding the Scope of Phenanthroline-Based Copper(I) Complexes in Photoredox Catalysis
Candidate: Thomas Peter Nicholls
2018
PhDDevelopment of a Novel Pressurised Hot Water Extraction Method and its Application in Natural Product Isolation and Synthesis
Candidate: Jeremy Just
2018
PhDApplications of the Controlled Oxidation of Pyrroles
Candidate: Kieran Josef Rihak
2018
PhDSynthesis of New Derivatives Targeting Mitochondrial Dysfunction
Candidate: Krystel Lee Woolley
2018
PhDNew Methods for the Synthesis of Nitrogen Containing, Biologically Relevant Small Molecules
Candidate: James Kenneth Howard
2015