Profiles

Aidan Bindoff

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Aidan Bindoff

Statistician and PhD Candidate
Wicking Dementia Research & Education Centre

Room 417-14 (level 4) , Medical Science 1

+61 419 507 945 (phone)

aidan.bindoff@utas.edu.au

Mr Bindoff is a research fellow at the Wicking Dementia Research and Education Centre. He provides statistical support for the multi-disciplinary team at Wicking, with interests in multi-level modelling, Bayesian modelling, machine learning, and network analysis.

Biography

Before joining Wicking, Aidan developed a novel method of inferring animal tracks from recorded light data using a Hidden Markov Model. This method is currently being used in marine ecology.

Career summary

Qualifications

BMarSc (1st Class Hons)

A New Method of Geolocation from Noisy Light Data

University of Tasmania

Australia

2016

Administrative expertise

Business management, big data management

View more on Mr Aidan Bindoff in WARP

Expertise

Statistics, Multilevel Models, Big Data Analysis, Text Analysis, Complex Network Analysis, Dementia, Neuroscience, MRI

Current projects

Tasmanian Healthy Brain Project, Understanding Dementia MOOC

Fields of Research

  • Aged health care (420301)
  • Central nervous system (320903)
  • Health services and systems (420399)
  • Cognitive neuroscience (520203)
  • Neurology and neuromuscular diseases (320905)
  • Geriatrics and gerontology (320210)
  • Health promotion (420603)
  • Behavioural neuroscience (520202)
  • Causes and prevention of crime (440201)
  • Other biological sciences (319999)
  • Psychiatry (incl. psychotherapy) (320221)
  • Neurosciences (320999)
  • Clinical pharmacology and therapeutics (321402)
  • Marine and estuarine ecology (incl. marine ichthyology) (310305)
  • Biological oceanography (370801)
  • Allied health and rehabilitation science (420199)
  • Primary health care (420319)
  • Health psychology (520304)
  • Applications in health (460102)
  • Virtual and mixed reality (460708)
  • Natural language processing (460208)
  • Health informatics and information systems (420308)
  • Speech recognition (460212)

Research Objectives

  • Clinical health (200199)
  • Health education and promotion (200203)
  • Health related to ageing (200502)
  • Mental health (200409)
  • Preventive medicine (200412)
  • Diagnosis of human diseases and conditions (200101)
  • Crime prevention (230402)
  • Behaviour and health (200401)
  • Evaluation of health and support services (200299)
  • Expanding knowledge in the biological sciences (280102)
  • Assessment and management of terrestrial ecosystems (180601)
  • Treatment of human diseases and conditions (200105)
  • Marine biodiversity (180504)
  • Palliative care (200309)
  • Prevention of human diseases and conditions (200104)
  • Criminal justice (230403)
  • Disability and functional capacity (200403)
  • Artificial intelligence (220403)
  • Expanding knowledge in the information and computing sciences (280115)

Publications

Total publications

30

Journal Article

(17 outputs)
YearCitationAltmetrics
2021Bartlett L, Brady JJR, Farrow M, Kim S, Bindoff A, et al., 'Change in modifiable dementia risk factors during COVID-19 lockdown: the experience of over 50s in Tasmania, Australia', Alzheimer's & Dementia: Translational Research & Clinical Interventions, 7, (1) pp. 1-11. ISSN 2352-8737 (2021) [Refereed Article]

DOI: 10.1002/trc2.12169 [eCite] [Details]

Co-authors: Bartlett L; Brady JJR; Farrow M; Kim S; Fair H; Vickers JC; Sinclair D

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2021Bindoff AD, Summers MJ, Hill E, Alty J, Vickers JC, 'Studying at university in later life slows cognitive decline: A long-term prospective study', Alzheimer's & Dementia: Translational Research & Clinical Interventions pp. 1-10. ISSN 2352-8737 (2021) [Refereed Article]

DOI: 10.1002/trc2.12207 [eCite] [Details]

Co-authors: Hill E; Alty J; Vickers JC

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2021Collins JM, Hill E, Bindoff A, King AE, Alty J, et al., 'Association Between Components of Cognitive Reserve and Serum BDNF in Healthy Older Adults', Frontiers in Aging Neuroscience, 13 pp. 1-9. ISSN 1663-4365 (2021) [Refereed Article]

DOI: 10.3389/fnagi.2021.725914 [eCite] [Details]

Co-authors: Collins JM; Hill E; King AE; Alty J; Summers MJ; Vickers JC

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2021Pietzuch M, Bindoff A, Jamadar S, Vickers JC, 'Interactive effects of the APOE and BDNF polymorphisms on functional brain connectivity: the Tasmanian Healthy Brain Project', Scientific Reports, 11, (1) pp. 1-13. ISSN 2045-2322 (2021) [Refereed Article]

DOI: 10.1038/s41598-021-93610-0 [eCite] [Details]

Co-authors: Pietzuch M; Vickers JC

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2020Doherty KV, Nguyen H, Eccleston CEA, Tierney L, Mason RL, et al., 'Measuring consumer access, appraisal and application of services and information for dementia (CAAASI-Dem): a key component of dementia literacy', BMC Geriatrics, 20 Article 484. ISSN 1471-2318 (2020) [Refereed Article]

DOI: 10.1186/s12877-020-01891-3 [eCite] [Details]

Co-authors: Doherty KV; Nguyen H; Eccleston CEA; Tierney L; Mason RL; Robinson A; Vickers J; McInerney F

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2020Fulopova B, Stuart KE, Bennett W, Bindoff A, King AE, et al., 'Regional differences in beta amyloid plaque deposition and variable response to midlife environmental enrichment in the cortex of APP/PS1 mice', Journal of Comparative Neurology pp. 1-14. ISSN 0021-9967 (2020) [Refereed Article]

DOI: 10.1002/cne.25060 [eCite] [Details]

Co-authors: Fulopova B; Stuart KE; Bennett W; King AE; Vickers JC; Canty AJ

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2020Hipfner JM, Prill MM, Studholme KR, Domalik AD, Tucker S, et al., 'Geolocator tagging links distributions in the non-breeding season to population genetic structure in a sentinel North Pacific seabird', PLoS ONE, 15, (11) Article e0240056. ISSN 1932-6203 (2020) [Refereed Article]

DOI: 10.1371/journal.pone.0240056 [eCite] [Details]

Citations: Scopus - 3Web of Science - 3

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2020Hoyle DJ, Peterson GM, Bindoff IK, Clinnick LM, Bindoff AD, et al., 'Clinical impact of antipsychotic and benzodiazepine reduction: findings from a multicomponent psychotropic reduction program within long-term aged care', International Psychogeriatrics pp. 1-13. ISSN 1041-6102 (2020) [Refereed Article]

DOI: 10.1017/S1041610220000940 [eCite] [Details]

Citations: Scopus - 2Web of Science - 1

Co-authors: Hoyle DJ; Peterson GM; Bindoff IK; Breen JL

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2020Lawler K, Kitsos A, Bindoff AD, Callisaya ML, Eccleston CEA, et al., 'Room for improvement: an online survey of allied health professionals' dementia knowledge', Australasian Journal on Ageing pp. 1-7. ISSN 1440-6381 (2020) [Refereed Article]

DOI: 10.1111/ajag.12886 [eCite] [Details]

Co-authors: Lawler K; Kitsos A; Callisaya ML; Eccleston CEA; Doherty KV

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2019Cleeland JB, Alderman R, Bindoff A, Lea M-A, McMahon CR, et al., 'Factors influencing the habitat use of sympatric albatrosses from Macquarie Island, Australia', Marine Ecology - Progress Series, 609 pp. 221-237. ISSN 0171-8630 (2019) [Refereed Article]

DOI: 10.3354/meps12811 [eCite] [Details]

Citations: Scopus - 4Web of Science - 4

Co-authors: Cleeland JB; Lea M-A; McMahon CR; Raymond B; Wotherspoon SJ; Hindell MA

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2019Eccleston C, Doherty K, Bindoff A, Robinson A, Vickers J, et al., 'Building dementia knowledge globally through the Understanding Dementia Massive Open Online Course (MOOC)', npj Science of Learning, 4 Article 3. ISSN 2056-7936 (2019) [Refereed Article]

DOI: 10.1038/s41539-019-0042-4 [eCite] [Details]

Citations: Scopus - 15Web of Science - 15

Co-authors: Eccleston C; Doherty K; Robinson A; Vickers J; McInerney F

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2019Vickers JC, King AE, McCormack GH, Bindoff AD, Adlard PA, 'Iron is increased in the brains of ageing mice lacking the neurofilament light gene', PLoS ONE, 14, (10) Article e0224169. ISSN 1932-6203 (2019) [Refereed Article]

DOI: 10.1371/journal.pone.0224169 [eCite] [Details]

Citations: Scopus - 1Web of Science - 1

Co-authors: Vickers JC; King AE; McCormack GH

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2018Bindoff AD, Wotherspoon SJ, Guinet C, Hindell MA, 'Twilight-free geolocation from noisy light data', Methods in Ecology and Evolution, 9, (5) pp. 1190-1198. ISSN 2041-210X (2018) [Refereed Article]

DOI: 10.1111/2041-210X.12953 [eCite] [Details]

Citations: Scopus - 7Web of Science - 82

Co-authors: Wotherspoon SJ; Hindell MA

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2018McInerney F, Doherty K, Bindoff A, Robinson A, Vickers J, 'How is palliative care understood in the context of dementia? Results from a massive open online course', Palliative medicine, 32, (3) pp. 594-602. ISSN 0269-2163 (2018) [Refereed Article]

DOI: 10.1177/0269216317743433 [eCite] [Details]

Citations: Scopus - 11Web of Science - 11

Co-authors: McInerney F; Doherty K; Robinson A; Vickers J

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2018Tang AD, Bennett W, Hadrill C, Collins J, Fulopova B, et al., 'Low intensity repetitive transcranial magnetic stimulation modulates skilled motor learning in adult mice', Scientific Reports, 8 Article 4016. ISSN 2045-2322 (2018) [Refereed Article]

DOI: 10.1038/s41598-018-22385-8 [eCite] [Details]

Citations: Scopus - 13Web of Science - 11

Co-authors: Bennett W; Hadrill C; Collins J; Fulopova B; Wills K; Puri R; Garry MI; Hinder MR; Summers JJ; Canty AJ

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2018Westbury JL, Gee P, Ling T, Brown DT, Franks KH, et al., 'RedUSe: reducing antipsychotic and benzodiazepine prescribing in residential aged care facilities', Medical Journal of Australia, 208, (9) pp. 398-403. ISSN 0025-729X (2018) [Refereed Article]

DOI: 10.5694/mja17.00857 [eCite] [Details]

Citations: Scopus - 52Web of Science - 56

Co-authors: Westbury JL; Gee P; Ling T; Brown DT; Franks KH; Bindoff I; Peterson GM

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2017Ward DD, Andel R, Saunders NL, Thow ME, Klekociuk SZ, et al., 'The BDNF Val66Met polymorphism moderates the effect of cognitive reserve on 36-month cognitive change in healthy older adults', Alzheimer's & Dementia: Translational Research & Clinical Interventions, 3, (3) pp. 323-331. ISSN 2352-8737 (2017) [Refereed Article]

DOI: 10.1016/j.trci.2017.04.006 [eCite] [Details]

Citations: Scopus - 7

Co-authors: Ward DD; Saunders NL; Thow ME; Klekociuk SZ; Vickers JC

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Chapter in Book

(2 outputs)
YearCitationAltmetrics
2018Goldberg LR, Price AD, Becker SE, Bindoff A, 'The critical importance of adopting a personhood lens' in reframing support and care for those with dementia', Dementia as Social Experience: Valuing Life and Care, Routledge, G Macdonald and J Mears (ed), United Kingdom ISBN 9780815374572 (2018) [Other Book Chapter]

[eCite] [Details]

Co-authors: Goldberg LR; Price AD; Becker SE

2018Goldberg LR, Price AD, Becker SE, Bindoff A, 'The critical importance of adopting a personhood lens' in reframing support and care for those with dementia', Dementia as Social Experience: Valuing Life and Care, Routledge, G Macdonald and J Mears (ed), United States, pp. 159-173. ISBN 9780815374572 (2018) [Research Book Chapter]

DOI: 10.4324/9781351241816-9 [eCite] [Details]

Co-authors: Goldberg LR; Price AD; Becker SE

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Conference Publication

(11 outputs)
YearCitationAltmetrics
2021Abela M, Maxwell H, Alty JE, Lawler K, Bindoff AD, et al., 'Physical activity for dementia risk reduction - not as easy as it sounds', 2021 Australian Dementia Forum, 31 May 2021 - 1 June 2021, online (2021) [Conference Extract]

[eCite] [Details]

Co-authors: Abela M; Maxwell H; Alty JE; Lawler K; Farrow M

2021Hill E, Collins J, Bindoff A, King A, Alty J, et al., 'Increased age and higher levels of cognitive reserve are associated with lower serum BDNF levels in healthy older adults', Australian Dementia Forum 2021, 31 May - 1 June, virtual (2021) [Conference Extract]

[eCite] [Details]

Co-authors: Hill E; Collins J; King A; Alty J; Summers M; Vickers J

2020Bartlett L, Doherty K, Farrow M, Bindoff A, Kim S, et al., 'Poster - The island study linking ageing and neurodegenerative disease (ISLAND): a longitudinal public health research program targeting dementia risk reduction', 2020 Alzheimer's Association International Conference, 26-30 July 2020, Online (2020) [Conference Extract]

[eCite] [Details]

Co-authors: Bartlett L; Doherty K; Farrow M; Kim S; Eccleston C; Hill E; Alty J; King E; Vickers JC

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2020Bartlett L, Doherty K, Farrow M, Bindoff A, Kim S, et al., 'The Island Study Linking Ageing and Neurodegenerative Disease (ISLAND): A longitudinal public health research program targeting dementia risk reduction', Alzheimer's & Dementia ISSN 1552-5260 (2020) [Conference Extract]

DOI: 10.1002/alz.045539 [eCite] [Details]

Co-authors: Bartlett L; Doherty K; Farrow M; Kim S; Eccleston C; Hill E; Alty JE; King AE; Vickers JC

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2020Doherty K, Bindoff A, Farrow M, McInerney F, Vickers J, 'ID: 594 / OS18 - Building knowledge and understanding of dementia in aged care personnel: the understanding dementia massive open online course', 34th Virtual International Conference of Alzheimer's Disease International - Hope in the age of dementia - New science. New knowledge. New solutions, 10-12 December, Online, pp. 129-129. (2020) [Conference Extract]

[eCite] [Details]

Co-authors: Doherty K; Farrow M; McInerney F; Vickers J

2020Hill E, Bindoff A, Bartlett L, Summers MJ, Vickers JC, 'Exploring uptake of a university-level educational intervention to prevent cognitive decline and reduce dementia risk: The Tasmanian Healthy Brain Project', Alzheimer's & Dementia ISSN 1552-5260 (2020) [Conference Extract]

DOI: 10.1002/alz.045477 [eCite] [Details]

Co-authors: Hill E; Bartlett L; Summers MJ; Vickers JC

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2020Kim S, Farrow M, Bindoff A, Borchard J, Doherty K, 'ID: 434 - Is a massive open online course accessible and effective for everyone? Native vs non-native English speakers', 34th Virtual International Conference of Alzheimer's Disease International - Hope in the age of dementia - New science. New knowledge. New solutions, 10-12 December, Online, pp. 387-387. (2020) [Conference Extract]

[eCite] [Details]

Co-authors: Kim S; Farrow M; Borchard J; Doherty K

2019Alty J, Bindoff A, Stuart K, Klekociuk S, Vickers J, 'Cognitive reserve in the baseline data of Tasmanian Healthy Brain Project: No effect of age or interaction with gender', The fourth annual NHMRC National Institute for Dementia Research (NNIDR) Australian Dementia Forum, 13-14 June, Hobart, Tasmania (2019) [Conference Extract]

[eCite] [Details]

Co-authors: Alty J; Stuart K; Klekociuk S; Vickers J

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2018Eccleston CEA, Doherty KV, Bindoff AD, Robinson AL, Vickers JC, et al., 'Transforming Knowledge of Dementia through the Understanding Dementia Massive Open Online Course (UDMOOC)', Alzheimer's Association International Conference, 22- 26 July 2018, Chicago, USA (2018) [Conference Extract]

[eCite] [Details]

Co-authors: Eccleston CEA; Doherty KV; Robinson AL; Vickers JC; McInerney F

2018Farrow M, Doherty KV, McInerney F, Klekociuk SZ, Bindoff A, et al., 'Improving Knowledge and Practice through Massive Open Online Dementia Education: The Understanding Dementia and Preventing Dementia MOOCs', Alzheimer's Association International Conference, 22-26 July 2018, Chicago, USA (2018) [Conference Extract]

[eCite] [Details]

Co-authors: Farrow M; Doherty KV; McInerney F; Klekociuk SZ; Vickers JC

2017Kirkcaldie MTK, Bindoff AD, Goldberg LM, Robinson AL, Vickers JC, 'Translating dementia knowledge to non-traditional settings and students', Alzheimer's Disease International (ADI), 26-29 April 2017, Kyoto, Japan (2017) [Conference Extract]

[eCite] [Details]

Co-authors: Kirkcaldie MTK; Goldberg LM; Robinson AL; Vickers JC

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Grants & Funding

Funding Summary

Number of grants

2

Total funding

$905,081

Projects

The future in our hands: Screening for preclinical Alzheimer's disease by analysing hand movements (2021 - 2025)$899,782
Description
Global dementia prevalence is rising. Alzheimers disease (AD), the most common cause, has devastating effects on peoples quality of life. AD has a preclinical (pre-AD) period of 1020 years when brain pathology silently progresses before any cognitive symptoms appear. Current tests for pre-AD are invasive, costly and unsuitable for screening at population level. If we cant identify people with pre-AD, we cant offer them early interventions. This hinders our strategies to reduce AD prevalence. We will develop a new scalable test (HandTest) by combining two innovative ideas: hand-movement tests to detect pre-AD >10 years before cognitive symptoms begin; and computer vision so people can self-test online at home. This unique approach builds on the recent discoveries that the posterior cingulate cortex (the first brain region to show abnormalities in pre-AD) is involved in hand-movement control, and that hand-movement patterns change in pre-AD. We will use exquisitely precise computer vision methods to automatically analyse movement data from thousands of participants, who complete the online test by simply opening and closing their hands repeatedly for 5 minutes in front of a standard computer, tablet or smartphone camera. The CI/AI team of experts in hand-movement analysis, pre-AD, computer vision, AD biomarkers and biostatistics has access to 3 well-phenotyped cohorts, >10,000 existing participants and a cutting-edge assay for a blood AD biomarker, ptau181. We will develop a HandTest algorithm to classify hand-movement data for pre-AD risk. In a longitudinal cohort we will determine HandTests precision to prospectively predict 5-year risks of cognitive decline and AD. This is the critical first step for up-scaling HandTest nationwide via memory clinics of the Australian Dementia Network. With worldwide access to computers, tablets and smartphones increasing, HandTest is scalable globally, potentially transforming dementia prevention and management.
Funding
National Health & Medical Research Council ($899,782)
Scheme
Grant-Ideas
Administered By
University of Tasmania
Research Team
Alty JE; Vickers JC; Bai Q; Bindoff AD; Hill E
Period
2021 - 2025
Grant Reference
2004051
Enhancing Early Detection of Cognitive Impairment in the Criminal Justice System (2017)$5,299
Description
This project scopes a research design to develop a method to enhance early detection of cognitive impairment.
Funding
University of Tasmania ($5,299)
Scheme
Grant-CAL Hothouse Research Enhancement Program
Administered By
University of Tasmania
Research Team
Spiranovic CA; Eckstein LG; McWhirter R; Kirkby KC; Watters P; Vickers JC; Bindoff AD
Year
2017