Profiles
Jessica Collins
Jessica Collins
Research Fellow
Medical Science 1, Level 4 , Hobart CBD Campuses
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View more on Dr Jessica Collins in WARP
Fields of Research
- Neurology and neuromuscular diseases (320905)
- Cellular nervous system (320902)
- Central nervous system (320903)
- Neurosciences (320999)
- Cognitive neuroscience (520203)
- Behavioural neuroscience (520202)
- Geriatrics and gerontology (320210)
- Artificial intelligence (460299)
- Peripheral nervous system (320906)
- Virtual and mixed reality (460708)
- Preventative health care (420605)
- Digital health (420302)
- Analytical biochemistry (310101)
- Behavioural epidemiology (420201)
- Cell development, proliferation and death (310102)
- Proteomics and intermolecular interactions (excl. medical proteomics) (310109)
- Primary health care (420319)
- Intensive care (320212)
Research Objectives
- Clinical health (200199)
- Health related to ageing (200502)
- Diagnosis of human diseases and conditions (200101)
- Determinants of health (200201)
- Preventive medicine (200412)
- Prevention of human diseases and conditions (200104)
- Behaviour and health (200401)
- Mental health (200409)
- Treatment of human diseases and conditions (200105)
- Expanding knowledge in the information and computing sciences (280115)
- Injury prevention and control (200408)
- Efficacy of medications (200102)
Publications
Total publications
13
Journal Article
(11 outputs)| Year | Citation | Altmetrics |
|---|---|---|
| 2021 | Bucher EA, Collins JM, King AE, Vickers JC, Kirkcaldie MTK, 'Coherence and cognition in the cortex: the fundamental role of parvalbumin, myelin, and the perineuronal net', Brain structure & Function, 226, (7) pp. 2041-2055. ISSN 1863-2653 (2021) [Refereed Article] DOI: 10.1007/s00429-021-02327-3 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Bucher EA; King AE; Vickers JC; Kirkcaldie MTK | |
| 2021 | Collins JM, Hill E, Bindoff A, King AE, Alty J, et al., 'Association Between Components of Cognitive Reserve and Serum BDNF in Healthy Older Adults', Frontiers in Aging Neuroscience, 13 pp. 1-9. ISSN 1663-4365 (2021) [Refereed Article] DOI: 10.3389/fnagi.2021.725914 [eCite] [Details] Co-authors: Hill E; Bindoff A; King AE; Alty J; Summers MJ; Vickers JC | |
| 2021 | Tang AD, Bennett W, Bindoff AD, Bolland S, Collins J, et al., 'Subthreshold repetitive transcranial magnetic stimulation drives structural synaptic plasticity in the young and aged motor cortex', Brain Stimulation, 14 pp. 1498-1507. ISSN 1935-861X (2021) [Refereed Article] DOI: 10.1016/j.brs.2021.10.001 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Bennett W; Bindoff AD; Langley RC; Garry MI; Summers JJ; Hinder MR; Canty AJ | |
| 2020 | Collins JM, Woodhouse A, Bye N, Vickers JC, King AE, et al., 'Pathological links between traumatic brain injury and dementia: Australian pre-clinical research', Journal of Neurotrauma, 37, (5) pp. 782-791. ISSN 0897-7151 (2020) [Refereed Article] DOI: 10.1089/neu.2019.6906 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 Co-authors: Woodhouse A; Bye N; Vickers JC; King AE; Ziebell JM | |
| 2019 | Collins JM, King AE, Woodhouse A, Kirkcaldie MTK, Vickers JC, 'Age moderates the effects of traumatic brain injury on beta-amyloid plaque load in APP/PS1 mice', Journal of Neurotrauma, 36, (11) pp. 1876-1889. ISSN 0897-7151 (2019) [Refereed Article] DOI: 10.1089/neu.2018.5982 [eCite] [Details] Citations: Scopus - 9Web of Science - 11 Co-authors: King AE; Woodhouse A; Kirkcaldie MTK; Vickers JC | |
| 2019 | Stuart KE, King AE, King NE, Collins JM, Vickers JC, et al., 'Late-life environmental enrichment preserves short-term memory and may attenuate microglia in male APP/PS1 mice', Neuroscience, 408 pp. 282-292. ISSN 0306-4522 (2019) [Refereed Article] DOI: 10.1016/j.neuroscience.2019.04.015 [eCite] [Details] Citations: Scopus - 9Web of Science - 11 Co-authors: Stuart KE; King AE; King NE; Vickers JC; Ziebell JM | |
| 2018 | O'Mara AR, Collins JM, King AE, Vickers JC, Kirkcaldie MTK, 'Accurate and unbiased quantitation of Amyloid-β fluorescence images using ImageSURF', Current Alzheimer Research, 16, (2) pp. 102-108. ISSN 1567-2050 (2018) [Refereed Article] DOI: 10.2174/1567205016666181212152622 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 Co-authors: O'Mara AR; King AE; Vickers JC; Kirkcaldie MTK | |
| 2018 | Tang AD, Bennett W, Hadrill C, Collins J, Fulopova B, et al., 'Low intensity repetitive transcranial magnetic stimulation modulates skilled motor learning in adult mice', Scientific Reports, 8 Article 4016. ISSN 2045-2322 (2018) [Refereed Article] DOI: 10.1038/s41598-018-22385-8 [eCite] [Details] Citations: Scopus - 18Web of Science - 16 Co-authors: Bennett W; Hadrill C; Fulopova B; Wills K; Bindoff A; Puri R; Garry MI; Hinder MR; Summers JJ; Canty AJ | |
| 2018 | Woodhouse A, Fernandez-Martos CM, Atkinson RAK, Hanson KA, Collins JM, et al., 'Repeat propofol anesthesia does not exacerbate plaque deposition or synapse loss in APP/PS1 Alzheimer's disease mice', BMC Anesthesiology, 18, (1) Article 47. ISSN 1471-2253 (2018) [Refereed Article] DOI: 10.1186/s12871-018-0509-5 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Woodhouse A; Fernandez-Martos CM; Atkinson RAK; Hanson KA; O'Mara AR; Terblanche N; Skinner MW; Vickers JC; King AE | |
| 2016 | Kirkcaldie MTK, Collins JM, 'The axon as a physical structure in health and acute trauma', Journal of Chemical Neuroanatomy, 76, (Part A) pp. 9-18. ISSN 0891-0618 (2016) [Refereed Article] DOI: 10.1016/j.jchemneu.2016.05.006 [eCite] [Details] Citations: Scopus - 11Web of Science - 11 Co-authors: Kirkcaldie MTK | |
| 2015 | Collins JM, King AE, Woodhouse A, Kirkcaldie MTK, Vickers JC, 'The effect of focal brain injury on beta-amyloid plaque deposition, inflammation and synapses in the APP/PS1 mouse model of Alzheimer's disease', Experimental Neurology, 267 pp. 219-29. ISSN 0014-4886 (2015) [Refereed Article] DOI: 10.1016/j.expneurol.2015.02.034 [eCite] [Details] Citations: Scopus - 37Web of Science - 38 Co-authors: King AE; Woodhouse A; Kirkcaldie MTK; Vickers JC |
Conference Publication
(2 outputs)| Year | Citation | Altmetrics |
|---|---|---|
| 2021 | Hill E, Collins J, Bindoff A, King A, Alty J, et al., 'Increased age and higher levels of cognitive reserve are associated with lower serum BDNF levels in healthy older adults', Australian Dementia Forum 2021, 31 May - 1 June, virtual (2021) [Conference Extract] Co-authors: Hill E; Bindoff A; King A; Alty J; Summers M; Vickers J | |
| 2014 | Collins J, King A, Woodhouse A, Kirkcaldie M, Vickers J, 'The effect of focal brain injury on beta-amyloid plaque deposition, inflammation and synapses in the APP/PS1 mouse model of Alzheimer's disease', Society for Neuroscience Meeting 2014, November 2014, Washington DC (2014) [Conference Extract] Co-authors: King A; Woodhouse A; Kirkcaldie M; Vickers J |
Grants & Funding
Funding Summary
Number of grants
4
Total funding
Projects
- Description
- This project aims to develop two new ultrasensitive single molecule array blood biomarker assays for the detection of the neurofilament proteins alpha-internexin and peripherin, which are specific to the central and peripheral nervous systems. We will then test the ability of these blood biomarker assays to detect central versus peripheral nervous system degeneration in mouse models of motor neuron disease and human motor neuron disease cases.
- Funding
- Motor Neurone Disease Research Australia ($98,626)
- Scheme
- Grant - Innovator
- Administered By
- University of Tasmania
- Research Team
- Collins J; King AE; Rogers ML
- Year
- 2022
- Description
- Pericytes, cells controlling blood flow in the brain, are injured post-stroke. This may increase brain injury and worsen neurological disability. This project will develop a blood test for detecting pericyte injury. This test may be useful for diagnosing blood flow impairments or predicting brain injury and neurological disability post-stroke.
- Funding
- Royal Hobart Hospital Research Foundation ($9,820)
- Scheme
- Grant-Incubator
- Administered By
- University of Tasmania
- Research Team
- Morris GP; Sutherland BA; Howells DW; King AE; Castley HJ; Courtney J; Collins J
- Year
- 2022
- Description
- Recently, proteins have been identified in the blood that can act as indicators that a person is at risk of developing dementia or neurodegenerative disease. This opens a window of opportunity for early intervention and preventative strategies. At present these proteins need to be measured using equipment not available to health professionals and the current methods use antibodies as biosensors. Antibodies are unstable, difficult to produce and expensive, and therefore not suited for wide-spread distribution of detection devices. Aptamers are single-stranded oligonucleotide (DNA or RNA) molecules, which can bind to target molecules with high affinity and specificity. They are ideal for use as biosensors in point-of-care devices as they are stable at room temperature and are cheap to produce. Our goal is to develop biomarker detection devices that are suitable for population-based screening. This project will develop aptamers to key biomarker indicators of brain health such as neurofilament light chain and tau.
- Funding
- Perpetual Trustees ($119,386)
- Scheme
- Grant-Trust Fund
- Administered By
- University of Tasmania
- Research Team
- King AE; Breadmore MC; Gell DA; Collins J; Shigdar S
- Year
- 2021
- Description
- This project will characterise a blood biomarker of neurodegeneration for prognostic and diagnostic value to predict cognitive decline and dementia.
- Funding
- Royal Hobart Hospital Research Foundation ($449,386)
- Scheme
- Grant-Major Project
- Administered By
- University of Tasmania
- Research Team
- Collins J; Vickers JC; King AE; Alty JE; Cooper PD
- Period
- 2020 - 2022
Research Supervision
Current
4
Current
| Degree | Title | Commenced |
|---|---|---|
| PhD | The Role of Wallerian Degeneration and Axon Loss in Dementia | 2019 |
| PhD | Excitatory-Inhibitory Relationships in Cerebral Cortex Affected by the Pathology of Alzheimer's Disease | 2019 |
| PhD | Understanding Axon Pathology in Ageing and Dementia | 2020 |
| PhD | Expanding Our Understanding of Neurofilament Proteins as Biomarkers of Neurodegeneration | 2022 |