Profiles
Rahul Patel
Rahul Patel
Senior Lecturer in Pharmacological Science
Room 4015, Level 4 , Pharmacy Building
There were only four students in the Master of Pharmaceutical Science course when Rahul Patel moved from India to study at UTAS in 2004. Five years later, when Dr Patel joined the University as an academic, this number had risen to eight. Today, the UTAS Master of Pharmaceutical Science attracts 45 to 50 students every year.
‘And one of the things I like most about this course is that it’s so popular among international students,’ says Dr Patel, Senior Lecturer in Pharmacological Sciences in the Division of Pharmacy, School of Medicine.
A prescription for passion
Dr Patel’s enthusiasm is shared by his students. In his first three years of lecturing, Dr Patel was awarded two teaching merit certificates by the university and he has since been twice voted by students as Pharmacy King. To use a medical metaphor, his passion is infectious.
Dr Patel knew from a young age that he wanted to study pharmacy. He remembers wondering as a child how an oral headache pill, for instance, could target and soothe the brain. His fascination with what medications do and how they work eventually led him to a Bachelor Degree in Pharmacy, employment as an industrial pharmacist, and postgraduate study at UTAS for both a Masters Degree and a PhD.
‘I decided at that time that all I wanted to do with my life was research because it is so different,’ says Dr Patel. ‘You embark on a project and you don’t know what the results will be.’
He completed his PhD within two and a half years and, while awaiting his results, worked as an intern pharmacist to secure Australian registration. Around this time an academic job was advertised for UTAS.
‘Research I knew and loved, but I didn’t have much experience with teaching. When I had my first lecture and I was standing in front of 60 third-year students, I know how nervous I was.
‘But one thing for sure, I knew I wanted to be myself.’
From that very first day, Dr Patel’s teaching style has focused on student participation. He starts his lectures with a chosen slide, gives the students some targeted information (which will have answers hidden within it), poses a question and then allows the students to find the answer. Sometimes they do and sometimes they don’t. Either way, the students are forced to engage, and the questions are formulated so that the essential knowledge is passed on through the process. This pattern of questions and answers is usually repeated five to six times each lecture.
Bench to bedside research
Today, Dr Patel combines his love of teaching and research in his role as course coordinator for the UTAS Master of Pharmaceutical Science. Half of this course comprises individual research, allowing Dr Patel’s students to explore ways that patients can be treated with medications outside of the hospital setting. There are numerous benefits in doing this, including the cost of inpatient care, the risk of infection, and the general happiness of patients who’d simply rather go home.
One of the reasons why patients remain in hospital for months after they could otherwise leave is the need to administer intravenous drugs to fully eradicate bacteria. To overcome this, the Master of Pharmaceutical Science students investigated whether the particular drug that is used for the treatment of bone infections was stable enough to be administered by a portable elastomeric device. This device, developed by a pharmaceutical company, is basically a small balloon that, once attached to an intravenous line, can be carried by a patient to pump medication over a 24-hour period. The Masters students’ research confirmed that the drug was in fact stable enough to be administered in this way and, within a month of being published, the technique was being used by patients.
Current students are now exploring the suitability of a multitude of other drugs to be administered in this way with the goal of developing a comprehensive and peer-reviewed resource for physicians worldwide.
‘When I decided to study for my Masters abroad, I chose Australia because many of my friends and cousins were pursuing their study here,’ Dr Patel said. ‘The reason I specifically chose UTAS was because, at that time, it was the only Australian university that offered a two-year Master of Pharmaceutical Science – all of the others only offered one-year or 18-month courses.
‘So it was crystal clear to me that I should study in Tasmania. Then it was straight away that I fell in love with this place – the greenery and the hills, the kindness of the people and the low pollution. And the first time I saw the River Derwent, it redefined my idea of a river. It seemed more like an ocean.
‘One thing I always tell my students is that I too was one of them but that if you work hard, this is the land of opportunity. That is what has happened to me.’
Dr Patel is a lecturer in Pharmacological Sciences, Division of Pharmacy, School of Medicine. Since his appointment as a lecturer in December 2009, Dr Patel has made a significant contribution in learning and teaching at both under- and post-graduate level. Apart from receiving two teaching merit certificates and exceptional feedback from the under-graduate and post-graduate students, Dr Patel has thoughtfully re-structured the Master of Pharmaceutical Science (MPharmSc) course to ensure a broader career and scholarly prospective for the graduates of this course. Dr Patel's research has resulted in a significant practice change in professional/clinical practice and also assisted a number of healthcare professionals in the area of pharmaceutical formulations. Dr Patel has actively participated in marketing of the MPharmSc course at National and International level resulting in almost a 100% increase in the student numbers. Dr Patel has also actively looked for quality graduate research students within the last one and half years of his appointment as a Graduate Research Coordinator as seen by the marked increase in the number of good quality Higher Degree Research applicants.
Biography
Dr Patel completed his Bachelor of Pharmacy degree from the Rajiv Gandhi University of Health Sciences, India. Before migrating to Australia, he worked as an Analytical Chemist at Elite Pharmaceuticals, India. Dr Patel obtained his Master of Pharmaceutical Science and PhD degrees from the University of Tasmania. After completion of his PhD in 2008, he worked as a registered pharmacist in Queensland, Australia. Dr Patel joined the Division of Pharmacy, School of Medicine as a lecturer in Pharmacological Sciences in December 2009.
Career summary
Qualifications
- PhD, University of Tasmania, Australia, 2008. Thesis: Enoxaparin: physicochemical investigations into the effects of freezing and heating
- MPharmSc, University of Tasmania, Australia, 2005. Thesis: Assessment of stability and activity of enoxaparin sodium by capillary electrophoresis
- Bachelor of Pharmacy, Rajiv Gandhi University of Health Sciences, India. 2002
Languages (other than English)
Hindi, Gujarati
Memberships
Professional practice
- Pharmaceutical Society of Australia
Administrative expertise
- Master of Pharmaceutical Science Course Coordinator
- Graduate Diploma of Pharmaceutical Science Course Coordinator
- Graduate Research Coordinator
- Established and manages the Pharmacy Division's chromatography laboratory
- A member of Division of Pharmacy Executive committee
Teaching
Infectious Disease, Medicinal Chemistry, Drug Development, Chromatography, Physiochemical Stability
Teaching expertise
Teaching philosophy: Dr Patel's teaching philosophy involves problem-based learning. Generally, each lecture starts with individual examples or problems, through the consideration of which students develop general principles and basic concepts. Dr Patel often incorporate humour in every lecture to foster student-lecturer relationship and to motivate students to learn. He believes in 'active learning' or 'class room participation'; hence, he tries to get everyone involved by posing various questions and also initiate feedback from students during lectures. It creates an environment in which all participants have the opportunity to learn and students explore issues and ideas in depth, from a variety of viewpoints.
Changes to Master of Pharmaceutical Science (MPharmSc) course structure: Dr Patel has been coordinating the MPharmSc course since July 2012. In his capacity as a course coordinator, Dr Patel has made significant changes to the course structure, including changing the course duration from one to two years. The changes were greatly accepted by the students, evident from students' feedback as well as significant increase in the number of MPharmSc students.
Scholarly Teaching: Dr Patel has been involved in a number of learning and teaching related scholarship activities. These include: 1) submission of an 'Expression of Interest' for teaching development grants (University of Tasmania; category (A); 2) completion of a project that investigated the barriers among pharmacy academics with regards to the use of Facebook as a teaching tool; and 3) completion of a project that evaluated the attitudes of post graduate students towards evidence based medicine.
Teaching responsibility
Dr Patel coordinates both the Master of Pharmaceutical Science and Graduate Diploma in Pharmaceutical Science course. He teaches into several units within the Bachelor of Pharmacy, Master of Pharmaceutical Science and Diploma in Pharmaceutical Science course programs.
- Pharmacology (CSA235)
- Medicinal Chemistry & Drug Development (CSA226)
- Infectious Disease (CSA344)
- Research Thesis A (CS444)
- Research Thesis B (CSA445)
- Research Thesis C (CSA446)
- Research Thesis D (CSA447)
- Research Thesis E (CSA448)
Research Appointments
In addition to reviewing scientific manuscripts for a number international journals (Chromatographic Science, Natures Protocols, Current Drug Safety, Journal of Clinical Pharmacy and Therapeutics), Dr Patel is on the editorial panel of the Journal of Paediatric Biochemistry, and the International Journal of Applied Biology and Pharmaceutical Technology.
Research Invitations
Dr Patel has presented his research at National and International forums. In 2010, he chaired a conference session at the International Conference on Analytical and Bioanalytical Techniques: Pharmaceutical R & D Summit (Hyderabad, India).
View more on Dr Rahul Patel in WARP
Expertise
- Chromatographic techniques
- Physico-chemical characterisation of pharmaceutical and nutraceutical products
- Investigating novel biological activities of carbohydrates
- Pharmacokinetic studiesHarm minimisation
Research Themes
Dr Patel's research aligns to the University's research theme of Better Health. His research interests include:
- Development of novel chromatographic techniques for the structure-activity characterisation of a group of glycosaminoglycans such heparins and fucoidans. Glycosaminoglycans are composed of heterogeneous mixture of highly negatively charged structurally complicated molecules. Using sophisticated analytical, in-vitro, ex-vivo and in-vivo techniques, Dr Patel and his colleagues identified novel glycosaminoglycan molecules having anti-asthmatic and anti-ulcerative colitis potential. Dr Patel and his group has developed a number of novel and robust analytical techniques that could be used to separate and identify structurally unknown molecules of glycosaminoglycans. For example, Dr Patel and his group developed a simple and sensitive method, for the analysis of batch-to-batch variation in pharmaceutical heparins. In December 2007, an increase in the number of adverse events including deaths were reported resulting from the use of contaminated batches of heparin. To ensure safety, the US Food and Drug Administration developed a reference test method, based on the method developed by Dr Patel and his group. All Pharmaceutical companies were instructed to use this reference method to detect impurities in all heparin batches to manufacture and enter the United States.
- Investigating the physico-chemical stability of extemporaneously prepared pharmaceutical formulations. Dr Patel has investigated the stability of a wide range of extemporaneous preparations and his research has contributed to the field of science and health. For example, the stability of one type of carbohydrate (iron polymaltose) formulation commonly used for severe iron-deficiency anaemia was unknown beyond 24 hours and therefore such preparations were traditionally prepared by Australian hospital pharmacists on a daily basis, resulting in subsequent workload and costs. Dr Patel's recent research indicated that the stability of such preparations can be safely extended from 24 hours to 28 days, and hence it is possible to prepare them in advance rather than on a daily basis. This finding has significantly reduced the workload of Australian hospital pharmacists as this formulation, based on his research finding, is now prepared commercially by Baxter Healthcare with an expiry date of 28 days. Also, Dr Patel has recently indicated that various types of antibiotics, when stored appropriately, are stable in different types of dialysis solutions. Such antibiotics premixed solutions can be prepared in advance by nurses and given to the patients. Therefore, patients can be treated at home rather than in the hospital. These findings have changed the current clinical practice as evident from the fact that based on his published research; the Royal Hobart Hospital has updated their guidelines for the preparation and storage of antibiotics in dialysis solutions.
- Minimising the particle and microbial associated harm among injecting drug users (IDU). Oral prescription opioids (morphine, oxycodone, buprenorphine) are not always administered the way they are intended. The way IDU prepare injecting solutions from prescription opioids make them susceptible to particle- and microbial- related harm (thrombosis, amputation, pulmonary embolism, skin infection, endocarditis etc.). Dr Patel and his colleagues are working on developing various techniques that can minimise the risk of particle and microbial related harm among IDU.
Collaboration
On a number of research projects, Dr Patel has collaborated with clinicians from the Royal Hobart Hospital, researchers from Australian Centre for Research on Separation Science (FSET), Centre of Research Excellence for Chronic Respiratory Disease, School of Human Life Sciences and division of Psychology, School of Medicine. Dr Patel has collaborated with a local Biotechnology company (Marinova Pty. Ltd) on a number of research projects. These collaborations have resulted in multiple joint publications.
Current projects
- Structure-activity characterisation of complicated glycosaminoglycans
- Non-anticoagulant derivatives of heparins for the management of inflammatory conditions
- Investigation of oral bioavailability and plasma pharmacokinetics of carbohydrates
- Minimising particle and microbial associated harm among injecting drug users
- Physico-chemical stability of various pharmaceutical dosage forms
Fields of Research
- Pharmaceutical sciences (321405)
- Clinical pharmacology and therapeutics (321402)
- Clinical pharmacy and pharmacy practice (321403)
- Infectious diseases (320211)
- Primary health care (420319)
- Health services and systems (420399)
- Respiratory diseases (320103)
- Nephrology and urology (320214)
- Basic pharmacology (321401)
- Pharmacology and pharmaceutical sciences (321499)
- Preventative health care (420605)
- Rheumatology and arthritis (320223)
- Agricultural biotechnology (300199)
- Health psychology (520304)
- Separation science (340109)
- Medical bacteriology (320701)
- Analytical chemistry (340199)
- Behavioural neuroscience (520202)
- Craniofacial biology (320301)
- Analytical biochemistry (310101)
- Disease surveillance (420202)
- Sport and exercise nutrition (321006)
- Other health sciences (429999)
- Cellular immunology (320404)
- Paramedicine (320219)
- Biologically active molecules (340401)
- Aged health care (420301)
- Bioassays (340102)
- Clinical social work practice (440901)
- Traditional Chinese medicine and treatments (420803)
- Central nervous system (320903)
- Health promotion (420603)
- Medical virology (320705)
- Nutrition and dietetics (321099)
- Epidemiology (420299)
- Medicinal and biomolecular chemistry (340499)
Research Objectives
- Clinical health (200199)
- Public health (excl. specific population health) (200499)
- Other health (209999)
- Expanding knowledge in the health sciences (280112)
- Efficacy of medications (200102)
- Provision of health and support services (200399)
- Treatment of human diseases and conditions (200105)
- Health education and promotion (200203)
- Diagnosis of human diseases and conditions (200101)
- Human biological preventatives (240801)
- Prevention of human diseases and conditions (200104)
- Health related to ageing (200502)
- Mental health services (200305)
- Nutrition (200410)
- Health policy evaluation (200205)
- Expanding knowledge in the environmental sciences (280111)
- Health system performance (incl. effectiveness of programs) (200206)
- Veterinary pharmaceutical products (241699)
- Urgent and critical care, and emergency medicine (200311)
- Injury prevention and control (200408)
- Human pain management (200103)
- Inpatient hospital care (200304)
- Evaluation of health outcomes (200202)
- Evaluation of health and support services (200299)
- Preventive medicine (200412)
Publications
Dr Patel's research work is published in peer reviewed journals, such as Integrative Biology, Analytical and Bioanalytical Chemistry, Plos One, Journal of Pharmaceutical Science, as well as in more specialised journals such as Expert Opinion on Investigational Drugs, Peritoneal Dialysis International and American Journal of Health System Pharmacy.
Total publications
90
Journal Article
(77 outputs)| Year | Citation | Altmetrics |
|---|---|---|
| 2023 | Ling CW, Sud K, Patel RP, Peterson GM, Castelino RL, 'Stability and compatibility of antibiotics in PD solutions call for including antibiotics for drug-resistant infections', Clinical Key Journal, 16, (2) pp. 394-395. ISSN 2048-8513 (2023) [Letter or Note in Journal] DOI: 10.1093/ckj/sfac131 [eCite] [Details] Citations: Web of Science - 1 Co-authors: Peterson GM | |
| 2023 | Ling CW, Sud K, Peterson G, Fethney J, Van C, et al., 'Characteristics and outcomes of hospital‑acquired and community‑acquired peritonitis in patients on peritoneal dialysis: a retrospective cohort study', Journal of nephrology pp. 1-12. ISSN 1724-6059 (2023) [Refereed Article] DOI: 10.1007/s40620-023-01597-w [eCite] [Details] Co-authors: Peterson G | |
| 2022 | Ling CW, Sud K, Van C, Peterson GM, Patel RP, et al., 'Practice variations in antibiotic administration for the management of peritonitis in patients on automated peritoneal dialysis in Australia and New Zealand', Peritoneal Dialysis International pp. 1-5. ISSN 0896-8608 (2022) [Refereed Article] DOI: 10.1177/08968608211069231 [eCite] [Details] Co-authors: Peterson GM; Razi Zaidi ST | |
| 2021 | Chong WC, Chellappan DK, Shukla SD, Peterson GM, Patel RP, et al., 'An appraisal of the current scenario in vaccine research for COVID-19', Viruses, 13 pp. 1-18. ISSN 1999-4915 (2021) [Refereed Article] DOI: 10.3390/v13071397 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 Co-authors: Shukla SD; Peterson GM; Eri RD; Shastri MD | |
| 2021 | Chong WC, Shastri MD, Peterson GM, Patel RP, Pathinayake PS, et al., 'The complex interplay between endoplasmic reticulum stress and the NLRP3 inflammasome: a potential therapeutic target for inflammatory disorders', Clinical & Translational Immunology, 10 Article e1247. ISSN 2050-0068 (2021) [Refereed Article] DOI: 10.1002/cti2.1247 [eCite] [Details] Citations: Scopus - 17Web of Science - 18 Co-authors: Shastri MD; Peterson GM | |
| 2021 | Ling CW, Sud K, Van C, Zaidi STR, Patel RP, et al., 'Pharmacokinetics of culture-directed antibiotics for the treatment of peritonitis in automated peritoneal dialysis: a systematic narrative review', Peritoneal Dialysis International, 41, (3) pp. 261-272. ISSN 0896-8608 (2021) [Refereed Article] DOI: 10.1177/0896860821990528 [eCite] [Details] Citations: Scopus - 4Web of Science - 3 Co-authors: Peterson GM | |
| 2021 | Shastri MD, Allam VSRR, Shukla SD, Jha NK, Paudel KR, et al., 'Interleukin-13: A pivotal target against influenza-induced exacerbation of chronic lung diseases', Life Sciences, 283 pp. 1-7. ISSN 0024-3205 (2021) [Refereed Article] DOI: 10.1016/j.lfs.2021.119871 [eCite] [Details] Citations: Scopus - 8Web of Science - 9 Co-authors: Shastri MD; Peterson GM | |
| 2021 | Weier NE, Nathwani D, Thursky K, Tangden T, Vlahovic-Palcevski V, et al., 'An international inventory of antimicrobial stewardship (AMS) training programmes for AMS teams', Journal of Antimicrobial Chemotherapy ISSN 0305-7453 (2021) [Refereed Article] DOI: 10.1093/jac/dkab053 [eCite] [Details] Citations: Scopus - 6Web of Science - 6 Co-authors: Weier NE | |
| 2020 | Asthana C, Peterson GM, Shastri M, Jones G, Patel R, 'Variation in plasma levels of glucosamine with chronic dosing: a possible reason for inconsistent clinical outcomes in osteoarthritis', Clinical Therapeutics, 42, (8) pp. e140-e149. ISSN 0149-2918 (2020) [Refereed Article] DOI: 10.1016/j.clinthera.2020.06.009 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Asthana C; Peterson GM; Shastri M; Jones G | |
| 2020 | Asthana C, Peterson GM, Shastri MD, Patel RP, 'A novel and sensitive HILIC-CAD method for glucosamine quantification in plasma and its application to a human pharmacokinetic study', Journal of Pharmaceutical and Biomedical Analysis, 178 Article 112954. ISSN 0731-7085 (2020) [Refereed Article] DOI: 10.1016/j.jpba.2019.112954 [eCite] [Details] Citations: Scopus - 4Web of Science - 2 Co-authors: Asthana C; Peterson GM; Shastri MD | |
| 2020 | Asthana C, Peterson GM, Shastri MD, Patel RP, 'Quality of glucosamine products: Is it a potential reason for inconsistent clinical outcomes in osteoarthritis?', Journal of AOAC International, 104, (1) pp. 211-215. ISSN 1944-7922 (2020) [Refereed Article] DOI: 10.1093/jaoacint/qsaa081 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Asthana C; Peterson GM; Shastri MD | |
| 2020 | Asthana C, Peterson GM, Shastri MD, Patel RP, 'Variation in the pharmacokinetics of glucosamine in healthy individuals', Rheumatology, 60, (3) pp. 1205-1209. ISSN 1462-0324 (2020) [Refereed Article] DOI: 10.1093/rheumatology/keaa418 [eCite] [Details] Co-authors: Asthana C; Peterson GM; Shastri MD | |
| 2020 | Batt TJ, Lincz LF, Prasad R, Patel RP, Shastri M, et al., 'Plasma levels of enoxaparin oligosaccharides, antifactor-Xa and thrombin generation in patients undergoing haemodialysis', Blood Coagulation and Fibrinolysis, 31, (2) pp. 152-159. ISSN 0957-5235 (2020) [Refereed Article] DOI: 10.1097/MBC.0000000000000892 [eCite] [Details] Co-authors: Shastri M; Jose MD | |
| 2020 | Harmanjeet H, Jani H, Zaidi STR, Wanandy T, Castelino RL, et al., 'Stability of ceftolozane and tazobactam in different peritoneal dialysis solutions', Peritoneal Dialysis International, 40, (5) pp. 470-476. ISSN 0896-8608 (2020) [Refereed Article] DOI: 10.1177/0896860820902590 [eCite] [Details] Citations: Scopus - 3Web of Science - 2 Co-authors: Harmanjeet H; Zaidi STR; Wanandy T; Castelino RL; Peterson GM | |
| 2020 | Nguyen TT, Harmanjeet H, Wanandy T, Castelino R, Sud K, et al., 'Pyridine levels in ceftazidime-peritoneal dialysis admixtures stored at body temperature', Peritoneal Dialysis International, 40, (2) pp. 171-178. ISSN 0896-8608 (2020) [Refereed Article] DOI: 10.1177/0896860819887636 [eCite] [Details] Citations: Scopus - 1Web of Science - 2 Co-authors: Harmanjeet H; Wanandy T; Castelino R; Jose MD; Peterson GM | |
| 2020 | Shastri M, Chong WC, Dua K, Peterson GM, Patel RP, et al., 'Emerging concepts and directed therapeutics for the management of asthma: regulating the regulators', Inflammopharmacology, 29, (1) pp. 15-33. ISSN 0925-4692 (2020) [Refereed Article] DOI: 10.1007/s10787-020-00770-y [eCite] [Details] Citations: Scopus - 10Web of Science - 8 Co-authors: Shastri M; Peterson GM | |
| 2020 | Shastri MD, Shukla SD, Chong WC, KC R, Dua K, et al., 'Smoking and COVID-19: what we know so far', Respiratory Medicine, 176 Article 106237. ISSN 0954-6111 (2020) [Refereed Article] DOI: 10.1016/j.rmed.2020.106237 [eCite] [Details] Citations: Scopus - 46Web of Science - 45 Co-authors: Shastri MD; KC R; Peterson GM; O'Toole RF | |
| 2019 | Amin MN, Ming LC, Neoh CF, Azizi FAN, Haseeb A, et al., 'Pharmacy students' inter-professional perceptions towards the pharmacy profession in Bangladesh, Saudi Arabia and Malaysia', Pharmacy Education, 19, (1) pp. 40-48. ISSN 1560-2214 (2019) [Refereed Article] Co-authors: Ming LC | |
| 2019 | Asthana C, Peterson GM, Shastri M, Patel RP, 'Development and validation of a novel high performance liquid chromatography-coupled with Corona charged aerosol detector method for quantification of glucosamine in dietary supplements', PLoS ONE, 14, (5) Article e0216039. ISSN 1932-6203 (2019) [Refereed Article] DOI: 10.1371/journal.pone.0216039 [eCite] [Details] Citations: Scopus - 9Web of Science - 9 Co-authors: Asthana C; Peterson GM; Shastri M | |
| 2019 | Choudhry FZ, Ming LC, Munawar K, Zaidi STR, Patel RP, et al., 'Health literacy studies conducted in Australia: A scoping review', International Journal of Environmental Research and Public Health, 16, (7) pp. 1-32. ISSN 1660-4601 (2019) [Refereed Article] DOI: 10.3390/ijerph16071112 [eCite] [Details] Citations: Scopus - 23Web of Science - 21 Co-authors: Ming LC; Zaidi STR; Elmer S | |
| 2019 | Izadi E, Afshan G, Patel RP, Rao V, Liew KB, et al., 'Levofloxacin: Insights into antibiotic resistance and product quality', Frontiers in Pharmacology, 10 pp. 1-7. ISSN 1663-9812 (2019) [Refereed Article] DOI: 10.3389/fphar.2019.00881 [eCite] [Details] Citations: Scopus - 14Web of Science - 13 Co-authors: Izadi E; Zaidi ST; Ming LC | |
| 2019 | Kaur H, Harmanjeet H, Wanandy T, Castelino RL, Sud K, et al., 'High pyridine generation in ceftazidime-icodextrin admixtures used to treat peritoneal dialysis-associated peritonitis', Clinical Therapeutics, 41, (11) pp. 2446-2451. ISSN 0149-2918 (2019) [Refereed Article] DOI: 10.1016/j.clinthera.2019.08.021 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Harmanjeet H; Wanandy T; Castelino RL; Jose MD; Peterson GM | |
| 2019 | Lee KS, Ming LC, Lean QY, Yee SM, Patel R, et al., 'Cross-border Collaboration to Improve Access to Medicine: Association of Southeast Asian nations perspective', Journal of Epidemiology and Global Health, 9, (2) pp. 93-97. ISSN 2210-6006 (2019) [Refereed Article] DOI: 10.2991/jegh.k.190506.001 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Ming LC | |
| 2019 | Lu D, Harmanjeet H, Wanandy T, Paine M, Peterson GM, et al., 'Physicochemical stability of extemporaneously prepared clonidine solutions for use in neonatal abstinence syndrome', Journal of Clinical Pharmacy and Therapeutics, 44, (6) pp. 883-887. ISSN 0269-4727 (2019) [Refereed Article] DOI: 10.1111/jcpt.13008 [eCite] [Details] Citations: Scopus - 1 Co-authors: Harmanjeet H; Wanandy T; Peterson GM | |
| 2019 | Shukla SD, Shastri MD, Chong WC, Dua K, Budden KF, et al., 'Microbiome-focused asthma management strategies', Current Opinion in Pharmacology, 46 pp. 143-149. ISSN 1471-4892 (2019) [Refereed Article] DOI: 10.1016/j.coph.2019.06.003 [eCite] [Details] Citations: Scopus - 9Web of Science - 9 Co-authors: Shastri MD; Mahmood MQ; Eri R; Peterson GM | |
| 2018 | Al Madfai F, Valah B, Zaidi STR, Wanandy T, Ming LC, et al., 'Stability of dobutamine in continuous ambulatory delivery devices', Journal of Clinical Pharmacy and Therapeutics, 43, (4) pp. 530-535. ISSN 1365-2710 (2018) [Refereed Article] DOI: 10.1111/jcpt.12674 [eCite] [Details] Citations: Scopus - 2Web of Science - 2 Co-authors: Al Madfai F; Zaidi STR; Wanandy T; Ming LC; Peterson GM | |
| 2018 | Al Madfai F, Zaidi STR, Ming LC, Wanandy T, Patel RP, 'Physical and chemical stability of ceftaroline in an elastomeric infusion device', European Journal of Hospital Pharmacy, 25, (e2) pp. e115-e119. ISSN 2047-9964 (2018) [Refereed Article] DOI: 10.1136/ejhpharm-2017-001221 [eCite] [Details] Citations: Scopus - 7Web of Science - 7 Co-authors: Al Madfai F; Zaidi STR; Ming LC; Wanandy T | |
| 2018 | Al Madfai F, Zaidi STR, Ming LC, Wanandy T, Patel RP, 'Stability of milrinone in continuous ambulatory delivery devices', American Journal of Health-System Pharmacy, 75, (9) pp. e241-e245. ISSN 1079-2082 (2018) [Refereed Article] DOI: 10.2146/ajhp170372 [eCite] [Details] Citations: Scopus - 1 Co-authors: Al Madfai F; Zaidi STR; Ming LC; Wanandy T | |
| 2018 | Harmanjeet H, Zaidi STR, Ming LC, Wanandy T, Patel RP, 'Physicochemical stability of voriconazole in elastomeric devices', European Journal of Hospital Pharmacy, e2 pp. e88-e92. ISSN 2047-9956 (2018) [Refereed Article] DOI: 10.1136/ejhpharm-2016-001170 [eCite] [Details] Citations: Scopus - 5Web of Science - 4 Co-authors: Harmanjeet H; Zaidi STR; Ming LC; Wanandy T | |
| 2018 | Ismail NFF, Neoh CF, Lean QY, Abdullah AH, Lim SM, et al., 'Facial candling for the treatment of Allergic Rhinitis in young adults: A qualitative study', Journal of pharmacy & bioallied sciences, 10, (4) pp. 199-207. ISSN 0976-4879 (2018) [Refereed Article] DOI: 10.4103/jpbs.JPBS_33_18 [eCite] [Details] Citations: Web of Science - 2 Co-authors: Ming LC | |
| 2018 | Mendes K, Harmanjeet H, Sedeeq M, Modi A, Wanandy T, et al., 'Stability of meropenem and piperacillin/tazobactam with heparin in various peritoneal dialysis solutions', Peritoneal Dialysis International, 38, (6) pp. 430-440. ISSN 0896-8608 (2018) [Refereed Article] DOI: 10.3747/pdi.2017.00274 [eCite] [Details] Citations: Scopus - 6Web of Science - 5 Co-authors: Harmanjeet H; Sedeeq M; Wanandy T; Zaidi STR; Ming LC; Castelino RL; Peterson GM | |
| 2018 | Mohammed Al-Worafi Y, Patel RP, Zaidi STR, Mohammed Alseragi W, Saeed Almutairi M, et al., 'Completeness and legibility of handwritten prescriptions in Sana'a, Yemen', Medical Principles and Practice, 27, (3) pp. 290-292. ISSN 1011-7571 (2018) [Refereed Article] DOI: 10.1159/000487307 [eCite] [Details] Citations: Scopus - 21Web of Science - 6 Co-authors: Zaidi STR; Ming LC | |
| 2018 | Patel RP, Jacob J, Sedeeq M, Ming LC, Wanandy T, et al., 'Stability of cefazolin in polyisoprene elastomeric infusion devices', Clinical therapeutics, 40, (4) pp. 664-667. ISSN 0149-2918 (2018) [Refereed Article] DOI: 10.1016/j.clinthera.2018.02.009 [eCite] [Details] Citations: Scopus - 6Web of Science - 7 Co-authors: Jacob J; Sedeeq M; Ming LC; Wanandy T; Zaidi STR; Peterson GM | |
| 2018 | Patel RP, Shastri MD, Ming LC, Zaidi STR, Peterson GM, 'Therapeutic potential of enoxaparin in lichen planus: exploring reasons for inconsistent reports', Frontiers in Pharmacology, 9 Article 586. ISSN 1663-9812 (2018) [Refereed Article] DOI: 10.3389/fphar.2018.00586 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Shastri MD; Ming LC; Zaidi STR; Peterson GM | |
| 2018 | Shastri MD, Shukla SD, Chong WC, Dua K, Peterson GM, et al., 'Role of oxidative stress in the pathology and management of human tuberculosis', Oxidative Medicine and Cellular Longevity, 2018 Article 7695364. ISSN 1942-0900 (2018) [Refereed Article] DOI: 10.1155/2018/7695364 [eCite] [Details] Citations: Scopus - 76Web of Science - 67 Co-authors: Shastri MD; Peterson GM; Eri R; O'Toole RF | |
| 2017 | Aidit S, Soh YC, Yap CS, Khan TM, Neoh CF, et al., 'Effect of standardized warfarin treatment protocol on anticoagulant effect: comparison of a warfarin medication therapy adherence clinic with usual medical care', Frontiers in Pharmacology, 8 Article 637. ISSN 1663-9812 (2017) [Refereed Article] DOI: 10.3389/fphar.2017.00637 [eCite] [Details] Citations: Scopus - 18Web of Science - 18 Co-authors: Ming LC | |
| 2017 | Apidi NA, Murugiah MK, Muthuveloo R, Soh YC, Caruso V, et al., 'Mobile medical applications for dosage recommendation, drug adverse reaction, and drug interaction', Therapeutic Innovation & Regulatory Science, 51, (4) pp. 480-485. ISSN 2168-4790 (2017) [Refereed Article] DOI: 10.1177/2168479017696266 [eCite] [Details] Citations: Scopus - 29Web of Science - 23 Co-authors: Caruso V; Ming LC | |
| 2017 | Izahar S, Lean QY, Hameed MA, Murugiah MK, Patel RP, et al., 'Content analysis of mobile health applications on diabetes mellitus', Frontiers in Endocrinology, 8 Article 318. ISSN 1664-2392 (2017) [Refereed Article] DOI: 10.3389/fendo.2017.00318 [eCite] [Details] Citations: Scopus - 43Web of Science - 33 Co-authors: Ming LC | |
| 2017 | Kah KS, Shahidullah A, Zaidi STR, Patel RP, Ming LC, et al., 'The crux of the medicine prices' controversy in Pakistan', Frontiers in Pharmacology, 8 Article 504. ISSN 1663-9812 (2017) [Contribution to Refereed Journal] DOI: 10.3389/fphar.2017.00504 [eCite] [Details] Citations: Scopus - 10Web of Science - 11 Co-authors: Zaidi STR; Ming LC | |
| 2017 | Kandel S, Zaidi STR, Wanandy T, Ming LC, Castelino RL, et al., 'Stability of ceftazidime and herapin in four different types of peritoneal dialysis solutions', Peritoneal Dialysis International, 38, (1) pp. 49-56. ISSN 0896-8608 (2017) [Refereed Article] DOI: 10.3747/pdi.2017.00115 [eCite] [Details] Citations: Scopus - 6Web of Science - 6 Co-authors: Zaidi STR; Wanandy T; Ming LC; Castelino RL | |
| 2017 | Khaleel I, Zaidi STR, Shastri MD, Eapen MS, Ming LC, et al., 'Investigations into the physical and chemical stability of concentrated co-trimoxazole intravenous infusions', European Journal of Hospital Pharmacy pp. 1-7. ISSN 2047-9956 (2017) [Refereed Article] DOI: 10.1136/ejhpharm-2017-001225 [eCite] [Details] Citations: Scopus - 1Web of Science - 5 Co-authors: Khaleel I; Zaidi STR; Shastri MD; Eapen MS; Ming LC; Wanandy T | |
| 2017 | Lee KS, Yee SM, Razi Zaidi ST, Patel RP, Yang Q, et al., 'Combating sale of counterfeit and falsified medicines online: a losing battle', Frontiers in Pharmacology, 8 Article 268. ISSN 1663-9812 (2017) [Contribution to Refereed Journal] DOI: 10.3389/fphar.2017.00268 [eCite] [Details] Citations: Scopus - 42Web of Science - 17 Co-authors: Razi Zaidi ST; Ming LC | |
| 2017 | Lu W, Chappell KJ, Walters JAE, Jacobson GA, Patel R, et al., 'The effect of varenicline and nicotine patch on smoking rate and satisfaction with smoking: an examination of the mechanism of action of two pre-quit pharmacotherapies', Psychopharmacology, 234, (13) pp. 1969-1976. ISSN 0033-3158 (2017) [Refereed Article] DOI: 10.1007/s00213-017-4604-y [eCite] [Details] Citations: Scopus - 6Web of Science - 6 Co-authors: Lu W; Chappell KJ; Walters JAE; Jacobson GA; Schuz N; Ferguson SG | |
| 2017 | McLean S, Patel R, Bruno R, 'Injection of pharmaceuticals designed for oral use: harms experienced and effective harm reduction through filtration', Current Topics in Behavioral Neurosciences, 34 pp. 77-98. ISSN 1866-3370 (2017) [Refereed Article] DOI: 10.1007/7854_2016_470 [eCite] [Details] Citations: Scopus - 7 Co-authors: McLean S; Bruno R | |
| 2017 | Ming LC, Yeoh SF, Patel RP, Zaidi STR, 'Revisiting the clinical evidence and economics of dexmedetomide use', Journal of Medical Marketing pp. 1-3. ISSN 1745-7904 (2017) [Letter or Note in Journal] DOI: 10.1177/1745790417697869 [eCite] [Details] Co-authors: Ming LC; Zaidi STR | |
| 2017 | Salmasi S, Wimmer BC, Khan TM, Patel RP, Ming LC, 'Quantitative exploration of medication errors among older people: a systematic review', Drugs and Therapy Perspectives, 34, (3) pp. 129-137. ISSN 1172-0360 (2017) [Refereed Article] DOI: 10.1007/s40267-017-0468-9 [eCite] [Details] Citations: Scopus - 9Web of Science - 7 Co-authors: Wimmer BC; Ming LC | |
| 2017 | Sharma D, Patel RP, Zaidi STR, Sarker MMR, Lean QY, et al., 'Interplay of the quality of ciprofloxacin and antibiotic resistance in developing countries', Frontiers in Pharmacology, 8 Article 546. ISSN 1663-9812 (2017) [Refereed Article] DOI: 10.3389/fphar.2017.00546 [eCite] [Details] Citations: Scopus - 48Web of Science - 43 Co-authors: Zaidi STR; Ming LC | |
| 2017 | Shastri MD, Peterson GM, Patel RP, 'Redefining Approaches to Asthma: Bridging the Gap Between Heparin and Its Anti-inflammatory Activities', Current allergy and asthma reports, 17, (10) ISSN 1529-7322 (2017) [Letter or Note in Journal] DOI: 10.1007/s11882-017-0738-6 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 Co-authors: Shastri MD; Peterson GM | |
| 2016 | Lu W, Ferguson SG, Nichols DS, Patel R, Jacobson GA, 'Application of an assay for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine for the assessment of tobacco-related harm', Journal of Pharmaceutical and Biomedical Analysis, 131 pp. 327-332. ISSN 0731-7085 (2016) [Refereed Article] DOI: 10.1016/j.jpba.2016.08.013 [eCite] [Details] Citations: Scopus - 4Web of Science - 3 Co-authors: Lu W; Ferguson SG; Nichols DS; Jacobson GA | |
| 2016 | Ramdas S, Yousaf F, Shastri MD, Wanandy T, Zaidi STR, et al., 'Stability of daptomycin in peritoneal dialysis solutions packaged in dual-compartment infusion bags', European Journal of Hospital Pharmacy, 23 pp. 57-60. ISSN 2047-9956 (2016) [Refereed Article] DOI: 10.1136/ejhpharm-2015-000651 [eCite] [Details] Co-authors: Ramdas S; Shastri MD; Wanandy T; Zaidi STR; Khandagale M; Jose M | |
| 2016 | Sultana K, Al Jeraisy M, Al Ammari M, Patel R, Zaidi STR, 'Attitude, barriers and facilitators to practice-based research: cross-sectional survey of hospital pharmacists in Saudi Arabia', Journal of Pharmaceutical Policy and Practice, 9, (4) Article 4. ISSN 2052-3211 (2016) [Refereed Article] DOI: 10.1186/s40545-016-0052-z [eCite] [Details] Citations: Scopus - 29 Co-authors: Zaidi STR | |
| 2016 | Tocaciu S, Oliver LJ, Lowenthal RM, Peterson GM, Patel R, et al., 'The effect of Undaria pinnatifida fucoidan on the pharmacokinetics of letrozole and tamoxifen in patients with breast cancer', Integrative Cancer Therapies pp. 1-7. ISSN 1534-7354 (2016) [Refereed Article] DOI: 10.1177/1534735416684014 [eCite] [Details] Citations: Scopus - 41Web of Science - 37 Co-authors: Lowenthal RM; Peterson GM; Shastri M; McGuinness G | |
| 2016 | Yousaf F, Razi Zaidi ST, Wanandy Troy, Jose MD, Patel RP, 'Stability of Cefepime in pH-Neutral Peritoneal Dialysis Solutions Packaged in Dual-Compartment Bags', Peritoneal Dialysis International, 36, (4) pp. 457-459. ISSN 0896-8608 (2016) [Contribution to Refereed Journal] DOI: 10.3747/pdi.2015.00169 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Razi Zaidi ST; Wanandy Troy; Jose MD | |
| 2015 | Lean QY, Eri RD, Fitton JH, Patel RP, Gueven N, 'Fucoidan extracts ameliorate acute colitis', PLoS One, 10, (6) Article e0128453. ISSN 1932-6203 (2015) [Refereed Article] DOI: 10.1371/journal.pone.0128453 [eCite] [Details] Citations: Scopus - 73Web of Science - 63 Co-authors: Lean QY; Eri RD; Gueven N | |
| 2015 | Lean QY, Eri RD, Randall-Demllo S, Sohal SS, Stewart N, et al., 'Orally Administered Enoxaparin Ameliorates Acute Colitis by Reducing Macrophage-Associated Inflammatory Responses', PLoS One, 10, (7) Article e0134259. ISSN 1932-6203 (2015) [Refereed Article] DOI: 10.1371/journal.pone.0134259 [eCite] [Details] Citations: Scopus - 20Web of Science - 16 Co-authors: Lean QY; Eri RD; Randall-Demllo S; Sohal SS; Stewart N; Peterson GM; Guven N | |
| 2015 | Lean QY, Gueven N, Eri RD, Bhatia R, Sohal SS, et al., 'Heparins in ulcerative colitis: proposed and potential reasons for inconsistent clinical outcomes', Expert Review of Clinical Pharmacology, 8, (6) pp. 795-811. ISSN 1751-2433 (2015) [Refereed Article] DOI: 10.1586/17512433.2015.1082425 [eCite] [Details] Citations: Scopus - 12Web of Science - 11 Co-authors: Lean QY; Gueven N; Eri RD; Sohal SS; Stewart N; Peterson GM | |
| 2015 | Lu W, Ferguson SG, Nichols D, Patel R, Jacobson GA, 'Determination of nicotine in cartridge-based electronic cigarettes', Analytical Letters, 48, (17) pp. 2715-2722. ISSN 0003-2719 (2015) [Refereed Article] DOI: 10.1080/00032719.2015.1048349 [eCite] [Details] Citations: Scopus - 4Web of Science - 5 Co-authors: Lu W; Ferguson SG; Nichols D; Jacobson GA | |
| 2015 | Ng H, Patel RP, Bruno R, Latham R, Wanandy T, et al., 'Filtration of crushed tablet suspensions has potential to reduce infection incidence in people who inject drugs', Drug and Alcohol Review, 34, (1) pp. 67-73. ISSN 0959-5236 (2015) [Refereed Article] DOI: 10.1111/dar.12196 [eCite] [Details] Citations: Scopus - 6Web of Science - 7 Co-authors: Ng H; Bruno R; Latham R; Wanandy T; McLean S | |
| 2015 | Patel RP, Li K, Shastri M, Wanandy T, Jose MD, 'Stability of ampicillin and amoxicillin in peritoneal dialysis solutions', American Journal of Health-System Pharmacy, 72, (1) pp. 13-14. ISSN 1079-2082 (2015) [Letter or Note in Journal] DOI: 10.2146/ajhp130717 [eCite] [Details] Citations: Scopus - 2Web of Science - 2 Co-authors: Li K; Shastri M; Wanandy T; Jose MD | |
| 2015 | Patel RP, Wanandy T, Zani RS, Jose MD, Shastri M, et al., 'Stability of trimethoprim in newly formulated liquid dosage form', Journal of Pharmacy Practice and Research, 45, (1) pp. 10-14. ISSN 1445-937X (2015) [Refereed Article] DOI: 10.1002/jppr.1127 [eCite] [Details] Co-authors: Wanandy T; Shastri M; Zaidi STR | |
| 2015 | Robiyanto R, Zaidi STR, Shastri MD, Castelino RL, Wanandy T, et al., 'Stability of tigecycline in different types of peritoneal dialysis solutions', Peritoneal Dialysis International, 36, (4) pp. 410-414. ISSN 0896-8608 (2015) [Refereed Article] DOI: 10.3747/pdi.2015.00170 [eCite] [Details] Citations: Scopus - 6Web of Science - 5 Co-authors: Zaidi STR; Shastri MD; Castelino RL; Wanandy T; Jose MD | |
| 2015 | Shastri MD, Stewart N, Eapen M, Peterson GM, Zaidi STR, et al., 'Opposing effects of low molecular weight heparins on the release of inflammatory cytokines from peripheral blood mononuclear cells of asthmatics', PLoS One, 10, (3) Article e0118798. ISSN 1932-6203 (2015) [Refereed Article] DOI: 10.1371/journal.pone.0118798 [eCite] [Details] Citations: Scopus - 21Web of Science - 21 Co-authors: Shastri MD; Stewart N; Eapen M; Peterson GM; Zaidi STR; Guven N; Sohal SS | |
| 2015 | Shastri MD, Stewart N, Horne J, Peterson GM, Gueven N, et al., 'In-vitro suppression of IL-6 and IL-8 release from human pulmonary epithelial cells by non-anticoagulant fraction of enoxaparin', PLoS One, 10, (5) Article 0126763. ISSN 1932-6203 (2015) [Refereed Article] DOI: 10.1371/journal.pone.0126763 [eCite] [Details] Citations: Scopus - 32Web of Science - 29 Co-authors: Shastri MD; Stewart N; Horne J; Peterson GM; Gueven N; Sohal SS | |
| 2015 | Shastri MD, Stewart N, Horne J, Zaidi STR, Sohal SS, et al., 'Non-anticoagulant fractions of enoxaparin suppress inflammatory cytokine release from peripheral blood mononuclear cells of allergic asthmatic individuals', PLoS One, 10, (6) Article e0128803. ISSN 1932-6203 (2015) [Refereed Article] DOI: 10.1371/journal.pone.0128803 [eCite] [Details] Citations: Scopus - 25Web of Science - 22 Co-authors: Shastri MD; Stewart N; Horne J; Zaidi STR; Sohal SS; Peterson GM; Korner H; Gueven N | |
| 2014 | Lean QY, Patel RP, Stewart N, Sohal SS, Guven N, 'Identification of pro-and anti-proliferative oligosaccharides of heparins', Integrative Biology, 6, (1) pp. 90 - 99. ISSN 0974-2816 (2014) [Refereed Article] DOI: 10.1039/c3ib40206a [eCite] [Details] Citations: Scopus - 13Web of Science - 12 Co-authors: Lean QY; Stewart N; Sohal SS; Guven N | |
| 2014 | Nowrin K, Sohal SS, Peterson G, Patel R, Walters EH, 'Epithelial-mesenchymal transition as a fundamental underlying pathogenic process in COPD airways: fibrosis, remodeling and cancer', Expert Reviews in Respiratory Medicine, 8, (5) pp. 547-559. ISSN 1747-6348 (2014) [Refereed Article] DOI: 10.1586/17476348.2014.948853 [eCite] [Details] Citations: Scopus - 73Web of Science - 67 Co-authors: Nowrin K; Sohal SS; Peterson G; Walters EH | |
| 2014 | Patel RP, Shastri MD, Bakkari M, Wanandy T, Jose MD, 'Stability of the combination of ceftazidime and cephazolin in icodextrin or pH neutral peritoneal dialysis solution', Peritoneal Dialysis International, 34, (2) pp. 212-218. ISSN 0896-8608 (2014) [Refereed Article] DOI: 10.3747/pdi.2013.00034 [eCite] [Details] Citations: Scopus - 11Web of Science - 9 Co-authors: Shastri MD; Wanandy T; Jose MD | |
| 2014 | Shastri M, Peterson GM, Stewart NJ, Sohal SS, Patel RP, 'Non-anticoagulant derivatives of heparin for the management of asthma: distant dream or close reality?', Expert Opinion on Investigational Drugs: Authoritative Analysis of Randd Trends, 23, (3) pp. 357-373. ISSN 1354-3784 (2014) [Refereed Article] DOI: 10.1517/13543784.2014.866092 [eCite] [Details] Citations: Scopus - 19Web of Science - 16 Co-authors: Shastri M; Peterson GM; Stewart NJ; Sohal SS | |
| 2013 | Patel RP, Shastri M, Wanandy ST, Jose MD, 'Physical and chemical stability of ceftazidime and cefazolin in peritoneal dialysis solutions packaged in dual-chamber infusion bags', American Journal of Health-System Pharmacy, 70, (17) pp. 1477-1478. ISSN 1079-2082 (2013) [Letter or Note in Journal] DOI: 10.2146/ajhp120692 [eCite] [Details] Citations: Web of Science - 1 Co-authors: Shastri M; Wanandy ST; Jose MD | |
| 2013 | Patel RP, Wanandy S, Loring S, Johns C, Hutchinson J, et al., 'Stability of diluted iron polymaltose in PVC infusion bags', Journal of Pharmacy Practice and Research, 43, (2) pp. 112-116. ISSN 1445-937X (2013) [Refereed Article] DOI: 10.1002/j.2055-2335.2013.tb00232.x [eCite] [Details] Citations: Scopus - 2 Co-authors: Wanandy S; Johns C; Hutchinson J; Shastri M | |
| 2013 | Shastri MD, Johns C, Hutchinson JP, Khandagale M, Patel RP, 'Ion exchange chromatographic separation and isolation of oligosaccharides of intact low-molecular-weight heparin for the determination of their anticoagulant and anti-inflammatory properties', Analytical and Bioanalytical Chemistry, 405, (18) pp. 6043-6052. ISSN 1618-2650 (2013) [Refereed Article] DOI: 10.1007/s00216-013-6996-9 [eCite] [Details] Citations: Scopus - 18Web of Science - 17 Co-authors: Shastri MD; Johns C; Hutchinson JP; Khandagale M | |
| 2012 | Patel PK, Patel RP, Brandon S, McLean S, Bruno R, et al., 'Effects of Filtration on the Presence of Particulate and Oxycodone Content of Injections Prepared from Crushed OxyContin® Tablets', Current Drug Safety, 7, (3) pp. 218-224. ISSN 1574-8863 (2012) [Refereed Article] DOI: 10.2174/157488612803251298 [eCite] [Details] Citations: Scopus - 9 Co-authors: Brandon S; McLean S; Bruno R; de Graaff B | |
| 2009 | Patel R, Narkowicz CK, Jacobson GA, 'Investigation of the effect of heating on the chemistry and antifactor Xa activity of enoxaparin', Journal of Pharmaceutical Science, 98, (5) pp. 1700 - 1711. ISSN 0022-3549 (2009) [Refereed Article] DOI: 10.1002/jps.21556 [eCite] [Details] Citations: Scopus - 16Web of Science - 14 Co-authors: Narkowicz CK; Jacobson GA | |
| 2009 | Patel R, Narkowicz CK, Jacobson GA, 'Investigation of freezing- and thawing-induced biological, chemical, and physical changes to enoxaparin solution', Journal of Pharmaceutical Science, 98, (3) pp. 1118 - 1128. ISSN 0022-3549 (2009) [Refereed Article] DOI: 10.1002/jps.21483 [eCite] [Details] Citations: Scopus - 12Web of Science - 12 Co-authors: Narkowicz CK; Jacobson GA | |
| 2009 | Patel R, Narkowicz CK, Jacobson GA, 'Effective reversed-phase ion pair high-performance liquid chromatography method for the separation and characterization of intact low-molecular-weight heparins ', Analytical Biochemistry, 387, (1) pp. 113-121. ISSN 0003-2697 (2009) [Refereed Article] DOI: 10.1016/j.ab.2009.01.007 [eCite] [Details] Citations: Scopus - 36Web of Science - 37 Co-authors: Narkowicz CK; Jacobson GA | |
| 2008 | Patel R, Narkowicz CK, Hutchinson J, Hilder EF, Jacobson GA, 'A simple capillary electrophoresis method for the rapid separation and determination of intact low molecular weight and unfractionated heparins', Journal of Pharmaceutical and Biomedical Analysis, 46, (1) pp. 30-35. ISSN 0731-7085 (2008) [Refereed Article] DOI: 10.1016/j.jpba.2007.10.009 [eCite] [Details] Citations: Scopus - 63Web of Science - 54 Co-authors: Narkowicz CK; Hutchinson J; Hilder EF; Jacobson GA | |
| 2008 | Patel R, Narkowicz CK, Jacobson GA, 'In vitro stability of enoxaparin solutions (20 mg/mL) diluted in 4% glucose', Clinical Therapeutics, 30, (10) pp. 1880-1885. ISSN 0149-2918 (2008) [Refereed Article] DOI: 10.1016/j.clinthera.2008.10.014 [eCite] [Details] Citations: Scopus - 6Web of Science - 7 Co-authors: Narkowicz CK; Jacobson GA |
Chapter in Book
(3 outputs)| Year | Citation | Altmetrics |
|---|---|---|
| 2016 | Dimond R, Patel RP, Zaidi STR, 'Fluoroquinolones', Drug Dosing in Obesity - Volume 1: Antimicrobials, Springer, STR Zaidi & JA Roberts (ed), Switzerland, pp. 45-52. ISBN 978-3-319-44034-7 (2016) [Research Book Chapter] DOI: 10.1007/978-3-319-44034-7_5 [eCite] [Details] Co-authors: Zaidi STR | |
| 2016 | Lean QY, Gueven N, Eri RD, Peterson GM, Patel RP, 'Non-Anticoagulant Oligosaccharides of Enoxaparin Relieve Chemical-Induced Acute Colitis', Advances in Medicine and Biology, Nova Science Publishers, LV Berhardt (ed), United States, pp. 87-104. ISBN 978-1-63483-988-4 (2016) [Research Book Chapter] Co-authors: Lean QY; Gueven N; Eri RD; Peterson GM | |
| 2016 | van Dyk E, Patel RP, Zaidi STR, 'Miscellaneous agents', Drug Dosing in Obesity - Volume 1: Antimicrobials, Springer, STR Zaidi & JA Roberts (ed), Switzerland, pp. 117-125. ISBN 978-3-319-44034-7 (2016) [Research Book Chapter] DOI: 10.1007/978-3-319-44034-7_11 [eCite] [Details] Co-authors: Zaidi STR |
Conference Publication
(9 outputs)| Year | Citation | Altmetrics |
|---|---|---|
| 2017 | Batt T, Prasad R, Lincz L, Patel RP, Shastri M, et al., 'Improving the safety of haemodialysis by optimising anticoagulation (ISHAN): a pilot study', 2017 Annual Scientific meeting Australian and New Zealand Society of Nephrology, 4-6 September 2017, Darwin, Australia (2017) [Conference Extract] Co-authors: Shastri M; Jose MD | |
| 2011 | Patel P, Patel RP, McLean SR, Bruno RB, 'Effects of Filtration on the Presence of Particulate and Buprenorphine Content of Injections Prepared from Crushed Subutex® Tablets', Drug and Alcohol Review, 13-16 November 2011, Hobart, Australia, pp. 72. ISSN 0959-5236 (2011) [Conference Extract] Co-authors: McLean SR; Bruno RB | |
| 2010 | McLean SR, Brandon S, Bruno RB, de Graaff B, Patel RP, 'Reducing harm from pharmaceutical opioid injection: The importance and effectiveness of filters', Drug and Alcohol Review, 28 November -1 December 2010, Canberra, Australia, pp. A51. (2010) [Conference Extract] Co-authors: McLean SR; Brandon S; Bruno RB; de Graaff B | |
| 2010 | McLean SR, Brandon S, de Graaff B, Bruno RB, Patel RP, 'Injecting OxyContin: What is the harm reduction eveidence?', Proceedings of ATDC 2010, 18-20 October 2010, Hobart, pp. 1. (2010) [Conference Extract] Co-authors: McLean SR; Brandon S; de Graaff B; Bruno RB | |
| 2009 | Patel RP, Narkowicz CK, Jacobson GA, 'A low-volume microtitre plate assay for determination of the AFXa activity of enoxaparin', Australasian Pharmaceutical Science Association Annual Conference Aus-CRS Symposium Program and Abstract book, 9-11 December 2009, Wrest Point Convention Centre, Hobart Tasmania, pp. 140. ISBN 978-0-646-52257-9 (2009) [Conference Extract] Co-authors: Narkowicz CK; Jacobson GA | |
| 2008 | Patel R, 'Stability enhancement ofl diluted enoxaparin sodium at paediatric dosage', Teams for tomorrow, 6-9 December 2008, Canberra, ACT, pp. 108. (2008) [Conference Extract] | |
| 2007 | Patel R, Narkowicz CK, Jacobson GA, 'The effect of heating on the chemistry and biological activity of enoxaparin', Australian Pharmaceutical Science Association, 8-11 December 2007, Manly NSW, pp. 205. ISBN 978-0-646-48458-7 (2007) [Conference Edited] Co-authors: Narkowicz CK; Jacobson GA | |
| 2007 | Patel R, Narkowicz CK, Jacobson GA, 'The effects of freezing and thawing on the AFXa activity of enoxaparin solution', Australian Pharmaceutical Science Association, 8-11 December 2007, Manly NSW, pp. 205. ISBN 978-0-646-48458-7 (2007) [Conference Edited] Co-authors: Narkowicz CK; Jacobson GA | |
| 2007 | Patel R, Narkowicz CK, Jacobson GA, 'Separation and characterisation of different low-molecular-weight heparins by reversed-phase ion-interaction high-performance liquid chromatography', Proceedings of the APSA Annual Conference, 8-11 December 2007, Manly NSW, pp. 205. ISBN 978-0-646-48458-7 (2007) [Conference Extract] Co-authors: Narkowicz CK; Jacobson GA |
Thesis
(1 outputs)| Year | Citation | Altmetrics |
|---|---|---|
| 2007 | Patel R, 'Enoxaparin: physicochemical investigations into the effects of freezing and heating' (2007) [PhD] |
Grants & Funding
Dr Patel's research projects have been funded by the University of Tasmania, Faculty of Health (University of Tasmania), Royal Hobart Hospital Research Foundation and Marinova Pty Ltd (an Australian biotechnology company specialising in manufacturing carbohydrate extracts). Dr Patel has a proven record in successfully achieving project goals. For example, Dr Patel successfully completed the projects funded in 2011, 2013 and 2014 by the Royal Hobart Hospital Research Foundation. Data generated from those projects led to eight peer reviewed publications and two conference publications.
Funding Summary
Number of grants
23
Total funding
Projects
- Description
- This project involves development of a simple, minimally invasive Volumetric Absorptive Microsampling (VAMS) analysis of paracetamol and alanine aminotransferase (ALT) levels to provide easier and safer management of patients with paracetamol toxicity due to overdose.
- Funding
- Royal Hobart Hospital Research Foundation ($9,812)
- Scheme
- Grant-Incubator
- Administered By
- University of Tasmania
- Research Team
- Veal FC; Patel RP; Jacobson GA; Nichols DS; Wanandy T; Handley S; Tran V
- Year
- 2022
- Description
- Tasmania's long history of iodine deficiency has improved, but some groups and individuals remain at-risk of adverse consequences, including brain-damage. Research is impeded by the high cost of current iodine status assays (due to having to send them interstate). This project will enhance research capacity by demonstrating the reliability of a novel, locally developed low-cost method.
- Funding
- Royal Hobart Hospital Research Foundation ($8,420)
- Scheme
- Grant-Incubator
- Administered By
- University of Tasmania
- Research Team
- Mirkazemi C; Hynes K; Patel RP; Nichols DS; Seal J; Burgess JR
- Year
- 2021
- Description
- Ceftazidime is the first line treatment for Pseudomonas peritonitis. Thus, the production of pyridine, a toxic degradation product of ceftazidime, raises some concern. This study will examine the degradation of ceftazidime in peritoneal dialysis solutions to propose some recommendations in order to minimise the exposure of patients to pyridine.
- Funding
- Royal Hobart Hospital Research Foundation ($9,458)
- Scheme
- Grant-Incubator
- Administered By
- University of Tasmania
- Research Team
- Patel RP; Wanandy ST; Peterson GM; Jose M
- Year
- 2019
- Description
- Tasmania does not currently have accredited laboratory facilities to determine iodine concentration of biological samples collected in Tasmanian research studies and monitoring projects.Sending samples interstate or overseas is becoming prohibitively expensive.This collaboration will facilitate establishment of cost-effective laboratory capacity in Tasmania.The proposed project will test and validate three types of assays for determination of iodine concentration in a range of biological samples routinely collected in Tasmanian research projects.
- Funding
- University of Tasmania ($9,800)
- Scheme
- Grant- Research Enhancement Program
- Administered By
- University of Tasmania
- Research Team
- Hynes K; Mirkazemi C; Patel RP; Oddy WH; Nichols DS; Burgess JR; Seal J
- Year
- 2018
- Description
- Administration of intravenous antibiotics by patients using home infusion (elastomeric) devices is growing. Cephalosporins are one of the commonly used antibiotics and their stability in elastomeric infusion devices is lacking. This project will measure the physical, chemical and microbial stability of cephalosporins to enable their use in such devices.
- Funding
- Royal Hobart Hospital Research Foundation ($9,339)
- Scheme
- Grant-Starter
- Administered By
- University of Tasmania
- Research Team
- Patel RP; Razi Zaidi ST; Wanandy ST; Cooley L
- Year
- 2018
- Description
- To date, there is no data available for the intraperitoneal administration of ceftolozane/tazobactam (C/T), the preferred and recommended route of administration of antibiotics in patients with peritoneal dialysis associated peritonitis. For an antibiotic to be administered intra-peritoneally, it needs to be stable in peritoneal dialysis solutions. Intraperitoneal administration of antibiotics to treat systemic infections [other than PDAP] in patients where administration of systemic antibiotics is impractical, is a routine clinical practice though the evidences are limited. The results of the proposed study may provide the stability information for clinicians to make such a choice where systemic administration of C/T is impractical by administering it intraperitoneally in patients that need it.
- Funding
- Merck Sharp & Dohme Australia ($26,851)
- Scheme
- Grant-Investigator Studies Program
- Administered By
- University of Tasmania
- Research Team
- Patel RP; Razi Zaidi ST
- Period
- 2018 - 2020
- Description
- Heparin has shown promising results in attenuating neuroinflammation following experimental traumatic brain injury (TBI); however, its anti-coagulative properties make it an unsuitable treatment due to the risk of bleeding. We have recently shown that the heparin derivative Dp4 retains the anti-inflammatory actions of heparin, but not the anti-coagulative properties. In this project, we will test whether Dp4 suppresses neuroinflammation following TBI in mice, potentially identifying it as a novel and valuable therapeutic agent for brain-injured patients.
- Funding
- Royal Hobart Hospital Research Foundation ($10,000)
- Scheme
- Grant-Starter
- Administered By
- University of Tasmania
- Research Team
- Bye N; Taylor BVM; Patel RP
- Year
- 2017
- Description
- Glucosamine is often taken by patients with osteoarthritis, with patients varying in their clinical response. This variation may be due to differences in absorption of the compound, which is known to be poorly absorbed. This study will investigate plasma levels, with a newly developed analytical procedure, in individuals taking glucosamine.
- Funding
- Royal Hobart Hospital Research Foundation ($9,837)
- Scheme
- Grant-Starter
- Administered By
- University of Tasmania
- Research Team
- Peterson GM; Jones G; Patel RP; Razi Zaidi ST
- Year
- 2017
- Funding
- Royal Hobart Hospital Research Foundation ($9,795)
- Scheme
- Grant-Starter
- Administered By
- University of Tasmania
- Research Team
- Wanandy ST; Patel RP; Razi Zaidi ST; Anderson T; Castelino RL
- Year
- 2016
- Description
- Industry interaction to test if Marinova's fucoidan extracts mobilise stem cells.
- Funding
- Marinova Pty Ltd ($27,048)
- Scheme
- Clinical Trial
- Administered By
- University of Tasmania
- Research Team
- Guven N; Eri RD; Ahuja KDK; Patel RP
- Year
- 2015
- Description
- This project represents industry interaction to develop Marinova's fucoidan extract for gut health.
- Funding
- Department of Industry, Science, Energy and Resources ($50,000)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Guven N; Davis E; Eri RD; Patel RP
- Year
- 2015
- Description
- This project aims to achieve the identification and evaluation of non-anticoagulant molecules of heparin that are responsible for the observed beneficial effects of heparin in patients with ulcerative colitis as well as to compare potential biomarkers in a preclinical muse model with ulcerative colitis patients.
- Funding
- Royal Hobart Hospital Research Foundation ($15,000)
- Scheme
- Grant-Clinical Research
- Administered By
- University of Tasmania
- Research Team
- Patel RP; Guven N; Eri RD; Bhatia R
- Year
- 2015
- Description
- We will isolate immune cells from persons with asthma and treat them in vitro with heparin fractions to determine their effects on the immune system.
- Funding
- Royal Hobart Hospital Research Foundation ($10,000)
- Scheme
- Grant-Clinical Research
- Administered By
- University of Tasmania
- Research Team
- Patel RP; Shastri M; Wanandy ST
- Year
- 2015
- Description
- Aim: In an international first, this project aims to achieve the evaluation and identification of heparin molecules that inhibit the effect of several important inflammatory mediators involved in the pathogenesis of asthma, without possessing significant anticoagulant effect, with a view towards examining the efficacy of identified molecules in patients with asthma. Methodology: Heparin molecules will be separated and isolated using an ion-chromatography technique. Participants will attend the clinic where 50mL of blood will be taken by a qualified nurse. Mononuclear cells will be isolated from the collected blood. Then the cells will be activated to produce inflammatory mediators in the presence or absence of heparin fractions. Outcome: This research will evaluate and identify the novel molecules responsible for the anti-asthmatic activity of the parent heparin. This study would provide better insight into the mechanism(s) of heparin for its anti-asthmatic activity. It could open new avenues for the development of a heparin formulation with high anti-asthmatic properties but devoid of any anticoagulant activity. This could potentially resolve the safety and non-compliance issues objected upon in previous clinical trials.
- Funding
- Royal Hobart Hospital Research Foundation ($4,998)
- Scheme
- Grant-Starter
- Administered By
- University of Tasmania
- Research Team
- Hunter CJ; Patel RP; Stewart NJ; Sohal SS
- Year
- 2014
- Funding
- University of Tasmania ($14,500)
- Scheme
- Grant-Research Enhancement (REGS)
- Administered By
- University of Tasmania
- Research Team
- Patel RP
- Year
- 2014
- Description
- Brown algal extracts, in particular those containing fucoidan have been shown to have potential applications in a number of health indications such as prediabetes, immunomodulation, cardiovascular disease, inflammation and gut health. With advances in technology, fucoidan extracts from brown seaweed can now be produced successfully on a commercial scale. These types of extracts are beginning to become more prevalent as ingredients in western dietary supplement markets. However, for the extracts to successfully enter this market, efficacy, safety and provenance must be proven to help gain acceptance. With this in mind, the objectives of this project include the following: to establish the efficacy of high purity fucoidan extract from Fucusvesiculosus in the treatment of ulcerative colitis in an animal model; and to compare the efficacy of the routes of administration of Fucusvesiculosus fucoidan in treating ulcerative colitis - with particular reference to oral and intra-peritoneal dosages.
- Funding
- Marinova Pty Ltd ($2,810)
- Scheme
- Contract Research
- Administered By
- University of Tasmania
- Research Team
- Peterson GM; Guven N; Patel RP
- Year
- 2013
- Description
- The physicochemical stability of amoxicillin, daptomycin and quinupristin/dalfopristin in peritoneal dialysis solution is currently unknown. This study will determine the stability of these antibiotics in various types of PD solutions and will supply crucial information to guide current clinical practice and to provide a more convenient service for patients with end stage renal disease.
- Funding
- Royal Hobart Hospital Research Foundation ($9,090)
- Scheme
- Grant-Research
- Administered By
- University of Tasmania
- Research Team
- Wanandy ST; Patel RP; Jose MD
- Year
- 2013
- Description
- Brown algal extracts, in particular those containing fucoidan and marine polyphloroglucinols, have been shown to have potential applications in a number of health indications such as pre-diabetes, immunomodulation, cardiovascular disease and inflammation. With advances in technology, fucoidan and marine polyphloroglucinol extracts from brown seaweed can now be produced successfully on a commercial scale. These types of extracts are beginning to become more prevalent as ingredients in western dietary supplement markets. However, for the extracts to successfully enter this market, efficacy, safety and provenance must be proven. With this in mind, the objectives of this PhD project include the following: to establish a generic analytical method that can be used to fingerprint and quantify fucoidan concentrations in solution, serum and urine; to determine the ability of a commercially available fucoidan/polyphloroglucinol extract (Maritech Synergy) to inhibit the uptake of glucose via an acute human study; to assess the effects of Maritech Synergy on health indications including glucose control, insulin sensitivity and pre-diabetes in a human setting; and to further the understanding of fucoidan and its metabolism.
- Funding
- Marinova Pty Ltd ($85,000)
- Scheme
- Clinical Trial
- Administered By
- University of Tasmania
- Research Team
- Peterson GM; Patel RP; Bereznicki LRE
- Period
- 2012 - 2014
- Funding
- University of Tasmania ($16,218)
- Scheme
- Grant-Institutional Research Scheme
- Administered By
- University of Tasmania
- Research Team
- Patel RP
- Year
- 2011
- Funding
- University of Tasmania ($6,950)
- Scheme
- Grant-Cross Theme
- Administered By
- University of Tasmania
- Research Team
- Patel RP; Hutchinson J; Johns CA; Jacobson GA; Narkowicz CK; Peterson GM
- Year
- 2011
- Funding
- Royal Hobart Hospital Research Foundation ($6,364)
- Scheme
- Grant-Research
- Administered By
- University of Tasmania
- Research Team
- Wanandy ST; Patel RP; Randall C; Jacobson GA; Holmes SE; Hutchinson C; Johns CA
- Year
- 2011
- Funding
- University of Tasmania ($5,000)
- Scheme
- Grant-New Appointees Research Grant Scheme (NARGS)
- Administered By
- University of Tasmania
- Research Team
- Patel RP
- Year
- 2010
- Funding
- University of Tasmania ($1,522)
- Scheme
- Grant-Conference Support Scheme
- Administered By
- University of Tasmania
- Research Team
- Patel RP
- Year
- 2010
Research Supervision
Dr Patel currently supervise multiple PhD, Master of Pharmacy by Research, Master of Pharmaceutical Science and Honours students.
Current
1
Completed
9
Current
| Degree | Title | Commenced |
|---|---|---|
| PhD | Improving Hospital Pharmacists Participation in Antimicrobial Stewardship | 2016 |
Completed
| Degree | Title | Completed |
|---|---|---|
| PhD | An Investigation into Possible Reasons Behind Inconsistent Clinical Outcomes of Glucosamine in Osteoarthritis Patients Candidate: Chhavi Asthana | 2020 |
| PhD | Investigation on the Utilization of Beneficial Microbes in Modulating the Gut Microbiota and Metabolic Profiles in Ageing Candidate: Ravichandra Vemuri | 2019 |
| PhD | Biological and Behavioural Markers of Smoking Reduction Candidate: Wenying Lu | 2017 |
| PhD | Usage of Metformin in Patients with Type 2 Diabetes Mellitus Candidate: Weiyi Huang | 2016 |
| Masters | Development, Validation and Application of an Analytical Method for the Determination of Fucose in Human Plasma Candidate: Ade Cahyana | 2016 |
| PhD | Bioprocess Monitoring Using Sequential Injection Capillary Electrophoresis Candidate: Ala Abdul Kareem Ahmad Alhusban | 2016 |
| PhD | Heparins and Fucoidans: Future therapeutic options for ulcerative colitis Candidate: Qi Ying Lean | 2016 |
| PhD | Non-anticoagulant Derivatives of Heparin for the Management of Asthma: Distant dream or close reality? Candidate: Madhur Shastri | 2015 |
| Masters | Drivers of Epithelial-Mesenchymal Transition in Chronic Obstructive Pulmonary Disease Candidate: Kaosia Nowrin | 2015 |