Profiles
Dawn Aitken
Dawn Aitken
Principal Research Fellow
Menzies Institute for Medical Research
Room 363c , MS2
+61 3 6226 7769 (phone)
Nearly one in ten Australians suffers from osteoarthritis, a chronic condition that affects the joints (e.g. hips, knees, hands, back or ankles).
Associate Professor Dawn Aitken leads a program of research which centres on improving our understanding and management of osteoarthritis. Osteoarthritis is a painful, disabling, and costly condition that affects the joints in our body including the knees, hips and hands.
Dawn is particularly interested in the role of exercise in the prevention and management of osteoarthritis. She works closely with clinicians to help improve the conservative (non-surgical) management of osteoarthritis and has published numerous papers on the relationship between physical activity and osteoarthritis. Her work has been used to develop new physical activity guidelines for people with chronic diseases by the US Department of Health and Human Services and he she has contributed to Australian policy white papers.
Dawn also leads or collaborates on a number of major clinical drug trials aimed at slowing down – or halting – the progression of osteoarthritis. Her team conducted the largest study in the world to examine whether the commonly used osteoporosis medication – zoledronic acid, can be used to treat knee osteoarthritis. The study found that zoledronic acid did not slow cartilage loss or improve knee pain. It provides definitive, high-quality evidence that zoledronic acid should not be used to treat knee osteoarthritis. This work was published in JAMA (The Journal of the American Medical Association) in April 2020. She has also worked on turmeric and fish oil for knee osteoarthritis, adalimumab for hand osteoarthritis, and zoledronic acid and denosumab for back pain.
Associate Professor Dawn Aitken is Head of the Musculoskeletal Health and Disease Research Group at the Menzies Institute for Medical Research. She is currently supported by a NHMRC/MRFF Career Development Fellowship. She completed her PhD in 2011 at the University of Tasmania examining early changes that occur in knee osteoarthritis. Before this she completed a Bachelor of Science, with Honours in Human Kinetics, at the University of Ottawa, Canada.
Career summary
Qualifications
- PhD, University of Tasmania, Australia. 2011 Thesis: The role of subchrondral bone in osteoarthritis
- Bachelor of Biotechnology (1st Class Hons), University of Tasmania, Australia. 2007
- Bachelor of Science (Human Kinetics), University of Ottawa, Canada. 2006
View more on AssocProf Dawn Aitken in WARP
Expertise
- Osteoarthritis
- Exercise/physical activity
- Clinical trials
- Pain
- Epidemiology
- Magnetic resonance imaging (MRI)
Research Themes
Dr Aitken's research is strongly aligned with the University's key theme of Better Health.
Awards
Award Highlights
- 2020 Young Tall Poppy (Tasmania)
- 2018 ASBMR Rising Star Award ($60,000 USD)
- 2018 Tasmanian STEM Young Researcher of the Year Award ($5,000)
- 2018 ANZBMS Kaye Ibbertson Award ($1,000) for the 5 best papers published in the last 5 years, in the field of bone and mineral research.
- 2017 ESCEO-Eli Lilly Scholarship. Top rated abstract award at the 2017 World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases ($3,200)
Fields of Research
- Rheumatology and arthritis (320223)
- Epidemiology (420299)
- Physiotherapy (420106)
- Geriatrics and gerontology (320210)
- Aged health care (420301)
- Orthopaedics (320216)
- Health promotion (420603)
- Primary health care (420319)
- Podiatry (420107)
- Traditional, complementary and integrative medicine (420899)
- Health counselling (420307)
- Health and community services (420305)
- Sports science and exercise (420799)
- Clinical sciences (320299)
- Health services and systems (420399)
- Nutritional epidemiology (420208)
- Multimorbidity (420314)
- Zoology (310999)
- Pain (320218)
- Autonomic nervous system (320901)
- Nutritional science (321004)
- Medical biotechnology diagnostics (incl. biosensors) (320602)
- Public health nutrition (321005)
- Health economics (380108)
- Behavioural epidemiology (420201)
- Sports medicine (320225)
- Implementation science and evaluation (420312)
- Endocrinology (320208)
- Biomechanics (420701)
- Clinical pharmacology and therapeutics (321402)
- Health equity (420602)
- Cellular immunology (320404)
- Solid tumours (321111)
- Medical biochemistry - lipids (320504)
- Allied health and rehabilitation science (420199)
- Exercise physiology (420702)
- Rehabilitation (420109)
Research Objectives
- Clinical health (200199)
- Treatment of human diseases and conditions (200105)
- Diagnosis of human diseases and conditions (200101)
- Health related to ageing (200502)
- Allied health therapies (excl. mental health services) (200301)
- Efficacy of medications (200102)
- Determinants of health (200201)
- Evaluation of health outcomes (200202)
- Behaviour and health (200401)
- Health education and promotion (200203)
- Human pain management (200103)
- Public health (excl. specific population health) (200499)
- Preventive medicine (200412)
- Health system performance (incl. effectiveness of programs) (200206)
- Primary care (200310)
- Expanding knowledge in the health sciences (280112)
- Community health care (200302)
- Nutrition (200410)
- Disability and functional capacity (200403)
- Teaching and curriculum (160399)
- Prevention of human diseases and conditions (200104)
- Overweight and obesity (200411)
Publications
Total publications
113
Highlighted publications
(8 outputs)| Year | Type | Citation | Altmetrics |
|---|---|---|---|
| 2020 | Journal Article | Cai G, Aitken D, Laslett LL, Pelletier J-P, Martel-Pelletier J, et al., 'Effect of intravenous zoledronic acid on tibiofemoral cartilage volume among patients with knee osteoarthritis with bone marrow lesions: a randomized clinical trial', JAMA - Journal of the American Medical Association, 323, (15) pp. 1456-1466. ISSN 0098-7484 (2020) [Refereed Article] DOI: 10.1001/jama.2020.2938 [eCite] [Details] Citations: Scopus - 37Web of Science - 36 Co-authors: Cai G; Laslett LL; Antony B; Blizzard L; Winzenberg T; Jones G | |
| 2020 | Journal Article | Wang Z, Jones G, Winzenberg T, Cai G, Laslett LL, et al., 'Effectiveness of Curcuma longa extract for the treatment of symptoms and effusion-synovitis of knee osteoarthritis : a randomized trial', Annals of Internal Medicine, 173, (11) pp. 861-869. ISSN 0003-4819 (2020) [Refereed Article] DOI: 10.7326/M20-0990 [eCite] [Details] Citations: Scopus - 36Web of Science - 33 Co-authors: Jones G; Winzenberg T; Cai G; Laslett LL; Singh A; Ding C; Antony B | |
| 2018 | Journal Article | Aitken D, Laslett LL, Pan F, Haugen IK, Otahal P, et al., 'A randomised double-blind placebo-controlled crossover trial of HUMira (adalimumab) for erosive hand OsteoaRthritis - the HUMOR trial', Osteoarthritis and Cartilage, 26, (7) pp. 880-887. ISSN 1063-4584 (2018) [Refereed Article] DOI: 10.1016/j.joca.2018.02.899 [eCite] [Details] Citations: Scopus - 69Web of Science - 66 Co-authors: Laslett LL; Pan F; Otahal P; Jones G | |
| 2018 | Journal Article | Balogun S, Aitken D, Winzenberg T, Wills K, Scott D, et al., 'Longitudinal associations of serum 25-hydroxyvitamin-D, physical activity, and knee pain and dysfunction with muscle loss in community-dwelling older adults', Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 73, (4) pp. 526-531. ISSN 1079-5006 (2018) [Refereed Article] DOI: 10.1093/gerona/glx157 [eCite] [Details] Citations: Scopus - 8Web of Science - 7 Co-authors: Balogun S; Winzenberg T; Wills K; Callisaya M; Jones G | |
| 2018 | Journal Article | Cai G, Laslett LL, Aitken D, Halliday A, Pan F, et al., 'Effect of Zoledronic Acid and Denosumab in patients with low back pain and modic change: A proof-of-principle trial', Journal of Bone and Mineral Research, 33, (5) pp. 773-782. ISSN 0884-0431 (2018) [Refereed Article] DOI: 10.1002/jbmr.3376 [eCite] [Details] Citations: Scopus - 22Web of Science - 22 Co-authors: Cai G; Laslett LL; Pan F; Otahal P; Winzenberg TM; Jones G | |
| 2018 | Journal Article | Munugoda IP, Wills K, Cicuttini F, Graves SE, Lorimer M, et al., 'The association between ambulatory activity, body composition and hip or knee joint replacement due to osteoarthritis: a prospective cohort study', Osteoarthritis and Cartilage, 26, (5) pp. 671-679. ISSN 1063-4584 (2018) [Refereed Article] DOI: 10.1016/j.joca.2018.02.895 [eCite] [Details] Citations: Scopus - 16Web of Science - 15 Co-authors: Munugoda IP; Wills K; Jones G; Callisaya ML | |
| 2013 | Journal Article | Dore DA, Winzenberg TM, Ding C, Otahal P, Pelletier JP, et al., 'The association between objectively measured physical activity and knee structural change using MRI', Annals of the Rheumatic Diseases, 72, (7) pp. 1170-1175. ISSN 0003-4967 (2013) [Refereed Article] DOI: 10.1136/annrheumdis-2012-201691 [eCite] [Details] Citations: Scopus - 75Web of Science - 76 Co-authors: Winzenberg TM; Ding C; Otahal P; Jones G | |
| 2012 | Journal Article | Laslett LL, Dore DA, Quinn SJ, Boon P, Ryan E, et al., 'Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial', Annals of the Rheumatic Diseases, 71, (8) pp. 1322-1328. ISSN 0003-4967 (2012) [Refereed Article] DOI: 10.1136/annrheumdis-2011-200970 [eCite] [Details] Citations: Scopus - 200Web of Science - 181 Co-authors: Laslett LL; Boon P; Winzenberg TM; Jones G |
Journal Article
(104 outputs)| Year | Citation | Altmetrics |
|---|---|---|
| 2022 | Bonakdari H, Pelletier JP, Blanco FJ, Rego-Perez I, Duran-Sotuela A, et al., 'Single nucleotide polymorphism genes and mitochondrial DNA haplogroups as biomarkers for early prediction of knee osteoarthritis structural progressors: use of supervised machine learning classifiers', BMC Medicine, 20, (1) Article 316. ISSN 1741-7015 (2022) [Refereed Article] DOI: 10.1186/s12916-022-02491-1 [eCite] [Details] Co-authors: Jones G | |
| 2022 | Cai G, Jones G, Cicuttini FM, Wluka AE, Wang Y, et al., 'Study protocol for a randomised controlled trial of diacerein versus placebo to treat knee osteoarthritis with effusion-synovitis (DICKENS)', Trials, 23, (1) Article 768. ISSN 1745-6215 (2022) [Refereed Article] DOI: 10.1186/s13063-022-06715-w [eCite] [Details] Co-authors: Cai G; Jones G; Antony B; de Graaff B; Thompson M; Winzenberg T; Buttigieg K | |
| 2022 | Cai G, Laslett LL, Bowes MA, Conaghan PG, Cicuttini F, et al., 'Effect of zoledronic acid with or without methylprednisolone on 3D bone area and bone shape in patients with symptomatic knee osteoarthritis: A post-hoc analysis of the ZAP2 trial', Seminars in Arthritis and Rheumatism, 56 Article 152054. ISSN 0049-0172 (2022) [Refereed Article] DOI: 10.1016/j.semarthrit.2022.152054 [eCite] [Details] Co-authors: Cai G; Laslett LL; Winzenberg T; Jones G | |
| 2022 | Liu M, Huang Y, Zhang H, Aitken D, Nevitt MC, et al., 'Restricting branched-chain amino acids within a high-fat diet prevents obesity', Metabolites, 12, (4) Article 334. ISSN 2218-1989 (2022) [Refereed Article] DOI: 10.3390/metabo12040334 [eCite] [Details] Citations: Scopus - 2Web of Science - 2 Co-authors: Jones G | |
| 2022 | Ma C, Aitken D, Wu F, Squibb K, Cicuttini F, et al., 'Association between radiographic hand osteoarthritis and bone microarchitecture in a population-based sample', Arthritis Research and Therapy, 24, (1) pp. 1-10. ISSN 1478-6362 (2022) [Refereed Article] DOI: 10.1186/s13075-022-02907-6 [eCite] [Details] Co-authors: Ma C; Wu F; Squibb K; Jones G | |
| 2022 | Sutton LP, Lahham A, Jose K, Moore MN, Antony B, et al., 'Feasibility of parkrun' for people with knee osteoarthritis: A mixed methods pilot study', Osteoarthritis and Cartilage Open, 4, (2) Article 100269. ISSN 2665-9131 (2022) [Refereed Article] DOI: 10.1016/j.ocarto.2022.100269 [eCite] [Details] Co-authors: Sutton LP; Jose K; Moore MN; Antony B; Cleland V; Winzenberg T; Jones G | |
| 2022 | Werdyani S, Aitken D, Gao Z, Liu M, Randell EW, et al., 'Metabolomic signatures for the longitudinal reduction of muscle strength over 10 years', Skeletal Muscle, 12, (1) pp. 1-15. ISSN 2044-5040 (2022) [Refereed Article] DOI: 10.1186/s13395-022-00286-9 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Jones G | |
| 2021 | Aitken D, Balogun S, Foong Y, Humphries D, Laslett L, et al., 'Clinical relevance of MRI knee abnormalities in Australian rules football players: a longitudinal study', BMJ Open Sport & Exercise Medicine, 7, (3) ISSN 2055-7647 (2021) [Refereed Article] DOI: 10.1136/bmjsem-2021-001097 [eCite] [Details] Co-authors: Foong Y; Laslett L; Pitchford N; Khan H; Jones G; Winzenberg T | |
| 2021 | Balogun S, Aitken D, Wu F, Scott D, Jones G, et al., 'Linear and nonlinear associations between physical activity, body composition, and multimorbidity over 10 years among community-dwelling older adults ', Journals of Gerontology. Series A: Biological Sciences and Medical Sciences, 76, (11) pp. 2015-2020. ISSN 1079-5006 (2021) [Refereed Article] DOI: 10.1093/gerona/glab086 [eCite] [Details] Citations: Scopus - 3Web of Science - 2 Co-authors: Balogun S; Wu F; Jones G; Winzenberg TM | |
| 2021 | Gandham A, Zengin A, Bonham MP, Brennan-Olsen SL, Aitken D, et al., 'Associations between socioeconomic status and obesity, sarcopenia, and sarcopenic obesity in community-dwelling older adults: The Tasmanian Older Adult Cohort Study', Experimental Gerontology, 156 pp. 1-7. ISSN 0531-5565 (2021) [Refereed Article] DOI: 10.1016/j.exger.2021.111627 [eCite] [Details] Citations: Web of Science - 1 Co-authors: Winzenberg TM; Jones G | |
| 2021 | Sutton L, Jose K, Betzold A, Hansen E, Laslett L, et al., 'Understanding the management of osteoarthritis in Australia: a qualitative study of GPs and orthopaedic surgeons in Tasmania, Australia', Osteoarthritis and Cartilage Open, 3, (4) Article 100218. ISSN 2665-9131 (2021) [Refereed Article] DOI: 10.1016/j.ocarto.2021.100218 [eCite] [Details] Co-authors: Sutton L; Jose K; Betzold A; Hansen E; Laslett L; Makin J; Winzenberg T | |
| 2021 | Thompson M, Aitken D, Balogun S, Cicuttini F, Jones G, 'Population Vitamin D Stores Are Increasing in Tasmania, and This Is Associated with Less BMD Loss over 10 Years', Journal of Clinical Endocrinology and Metabolism, 106, (8) pp. E2995-E3004. ISSN 0021-972X (2021) [Refereed Article] DOI: 10.1210/clinem/dgab197 [eCite] [Details] Citations: Scopus - 1 Co-authors: Thompson M; Balogun S; Jones G | |
| 2021 | Zheng S, Tu L, Cicuttini F, Zhu Z, Han W, et al., 'Depression in patients with knee osteoarthritis: risk factors and associations with joint symptoms', BMC Musculoskeletal Disorders, 22, (1) pp. 1-10. ISSN 1471-2474 (2021) [Refereed Article] DOI: 10.1186/s12891-020-03875-1 [eCite] [Details] Citations: Scopus - 13Web of Science - 11 Co-authors: Zheng S; Zhu Z; Han W; Antony B; Winzenberg T; Blizzard L; Jones G; Ding C | |
| 2021 | Zheng S, Wu F, Winzenberg T, Cicuttini F, Wluka AE, et al., 'The cross-sectional and longitudinal associations of dietary patterns with knee symptoms and MRI detected structure in patients with knee osteoarthritis', Osteoarthritis and Cartilage: Journal of The Osteoarthritis Research Society International, 29, (4) pp. 527-535. ISSN 1063-4584 (2021) [Refereed Article] DOI: 10.1016/j.joca.2020.12.023 [eCite] [Details] Co-authors: Zheng S; Wu F; Winzenberg T; Antony B; Blizzard L; Ding C | |
| 2020 | Ahedi H, Aitken D, Blizzard L, Cicuttini F, Jones G, 'Quantification of hip effusion-synovitis and its cross-sectional and longitudinal associations with hip pain, MRI findings and early radiographic hip OA', BMC Musculoskeletal Disorders, 21, (1) Article 533. ISSN 1471-2474 (2020) [Refereed Article] DOI: 10.1186/s12891-020-03532-7 [eCite] [Details] Citations: Scopus - 7Web of Science - 6 Co-authors: Ahedi H; Blizzard L; Jones G | |
| 2020 | Balogun S, Scott D, Cicuttini F, Jones G, Aitken D, 'Longitudinal study of the relationship between physical activity and knee pain and functional limitation in community-dwelling older adults', Archives of Gerontology and Geriatrics, 90 Article 104101. ISSN 0167-4943 (2020) [Refereed Article] DOI: 10.1016/j.archger.2020.104101 [eCite] [Details] Citations: Scopus - 6Web of Science - 6 Co-authors: Balogun S; Jones G | |
| 2020 | Balogun SA, Graves SE, Lorimer M, Cicuttini F, Scott D, et al., 'Do older adults with low muscle mass or strength, in the presence of obesity, have an increased risk of joint replacement over 13 Years?', Calcified Tissue International, 107, (1) pp. 10-17. ISSN 0171-967X (2020) [Refereed Article] DOI: 10.1007/s00223-020-00698-z [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Balogun SA; Scott D; Jones G | |
| 2020 | Cai G, Aitken D, Laslett LL, Hill C, Wluka AE, et al., 'The association between change in bone marrow lesion size and change in tibiofemoral cartilage volume and knee symptoms', Rheumatology, (November) pp. 1-10. ISSN 1462-0324 (2020) [Refereed Article] DOI: 10.1093/rheumatology/keaa716 [eCite] [Details] Citations: Scopus - 3Web of Science - 4 Co-authors: Cai G; Laslett LL; Jones G | |
| 2020 | Cai G, Aitken D, Laslett LL, Pelletier J-P, Martel-Pelletier J, et al., 'Effect of intravenous zoledronic acid on tibiofemoral cartilage volume among patients with knee osteoarthritis with bone marrow lesions: a randomized clinical trial', JAMA - Journal of the American Medical Association, 323, (15) pp. 1456-1466. ISSN 0098-7484 (2020) [Refereed Article] DOI: 10.1001/jama.2020.2938 [eCite] [Details] Citations: Scopus - 37Web of Science - 36 Co-authors: Cai G; Laslett LL; Antony B; Blizzard L; Winzenberg T; Jones G | |
| 2020 | Cai G, Cicuttini F, Aitken D, Laslett LL, Zhu Z, et al., 'Comparison of radiographic and MRI osteoarthritis definitions and their combination for prediction of tibial cartilage loss, knee symptoms and total knee replacement: a longitudinal study', Osteoarthritis and Cartilage, 28 pp. 1062-1070. ISSN 1063-4584 (2020) [Refereed Article] DOI: 10.1016/j.joca.2020.04.017 [eCite] [Details] Citations: Scopus - 5Web of Science - 4 Co-authors: Cai G; Laslett LL; Winzenberg T; Jones G | |
| 2020 | Cai G, Keen HI, Host LV, Aitken D, Laslett LL, et al., 'Once-yearly zoledronic acid and change in abdominal aortic calcification over 3 years in postmenopausal women with osteoporosis: results from the HORIZON Pivotal Fracture Trial', Osteoporosis International, 31, (9) pp. 1741-1747. ISSN 0937-941X (2020) [Refereed Article] DOI: 10.1007/s00198-020-05430-z [eCite] [Details] Citations: Scopus - 6Web of Science - 7 Co-authors: Cai G; Laslett LL; Winzenberg T; Jones G | |
| 2020 | Cai G, Otahal P, Cicuttini F, Wu F, Munugoda IP, et al., 'The association of subchondral and systemic bone mineral density with osteoarthritis-related joint replacements in older adults', Osteoarthritis and Cartilage, 28, (4) pp. 438-445. ISSN 1063-4584 (2020) [Refereed Article] DOI: 10.1016/j.joca.2020.02.832 [eCite] [Details] Citations: Scopus - 2Web of Science - 1 Co-authors: Cai G; Otahal P; Wu F; Munugoda IP; Jones G | |
| 2020 | Crisford P, Aitken D, Winzenberg T, Venn A, Cleland V, 'What factors are associated with physical activity promotion in the podiatry setting? a cross-sectional study', Journal of Science and Medicine in Sport pp. 1-7. ISSN 1440-2440 (2020) [Refereed Article] DOI: 10.1016/j.jsams.2020.08.008 [eCite] [Details] Citations: Scopus - 1 Co-authors: Crisford P; Winzenberg T; Venn A; Cleland V | |
| 2020 | Gandham A, Zengin A, Bonham MP, Winzenberg T, Balogun S, et al., 'Incidence and predictors of fractures in older adults with and without obesity defined by body mass index versus body fat percentage', Bone, 140 Article 115546. ISSN 8756-3282 (2020) [Refereed Article] DOI: 10.1016/j.bone.2020.115546 [eCite] [Details] Citations: Scopus - 12Web of Science - 12 Co-authors: Winzenberg T; Balogun S; Wu F; Jones G; Scott D | |
| 2020 | Munugoda IP, Beavers DP, Wirth W, Aitken DA, Loeser RF, et al., 'The effect of weight loss on the progression of meniscal extrusion and size in knee osteoarthritis: a post-hoc analysis of the Intensive Diet and Exercise for Arthritis (IDEA) trial', Osteoarthritis and Cartilage, 28, (4) pp. 410-417. ISSN 1063-4584 (2020) [Refereed Article] DOI: 10.1016/j.joca.2020.01.006 [eCite] [Details] Citations: Scopus - 6Web of Science - 6 Co-authors: Munugoda IP | |
| 2020 | Munugoda IP, Brennan-Olsen SL, Wills K, Cai G, Graves SE, et al., 'The association between socioeconomic status and joint replacement of the hip and knee: a population-based cohort study of older adults in Tasmania', Internal Medicine Journal pp. 1-29. ISSN 1444-0903 (2020) [Refereed Article] DOI: 10.1111/imj.15066 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Munugoda IP; Wills K; Cai G; Callisaya ML; Jones G | |
| 2020 | Munugoda IP, Pan F, Wills K, Mattap SM, Cicuttini F, et al., 'Identifying subgroups of community-dwelling older adults and their prospective associations with long-term knee osteoarthritis outcomes', Clinical Rheumatology, 39, (5) pp. 1429-1437. ISSN 0770-3198 (2020) [Refereed Article] DOI: 10.1007/s10067-019-04920-8 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Munugoda IP; Pan F; Wills K; Mattap SM; Jones G; Callisaya ML | |
| 2020 | Thompson MJW, Jones G, Balogun S, Aitken DA, 'Constitutive melanin density is associated with prevalent and short-term, but not long-term, incident fracture risk in older Caucasian adults', Osteoporosis International, 31, (8) pp. 1517-1524. ISSN 0937-941X (2020) [Refereed Article] DOI: 10.1007/s00198-020-05304-4 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Thompson MJW; Jones G; Balogun S | |
| 2020 | Thompson MJW, Jones G, Balogun SA, Aitken DA, 'Skin photosensitivity is associated with 25-Hydroxyvitamin D and BMD but not fractures independent of melanin density in older caucasian adults', Calcified Tissue International pp. 1-10. ISSN 0171-967X (2020) [Refereed Article] DOI: 10.1007/s00223-020-00728-w [eCite] [Details] Co-authors: Thompson MJW; Jones G; Balogun SA | |
| 2020 | Wang Z, Jones G, Winzenberg T, Cai G, Laslett LL, et al., 'Effectiveness of Curcuma longa extract for the treatment of symptoms and effusion-synovitis of knee osteoarthritis : a randomized trial', Annals of Internal Medicine, 173, (11) pp. 861-869. ISSN 0003-4819 (2020) [Refereed Article] DOI: 10.7326/M20-0990 [eCite] [Details] Citations: Scopus - 36Web of Science - 33 Co-authors: Jones G; Winzenberg T; Cai G; Laslett LL; Singh A; Ding C; Antony B | |
| 2020 | Zhao T, Ahmad H, Winzenberg T, Aitken D, de Graaff B, et al., 'Cross-sectional and temporal differences in health-related quality of life of people with and without osteoarthritis: a 10-year prospective study', Rheumatology pp. 1-8. ISSN 1462-0324 (2020) [Refereed Article] DOI: 10.1093/rheumatology/keaa787 [eCite] [Details] Citations: Scopus - 3Web of Science - 2 Co-authors: Zhao T; Ahmad H; Winzenberg T; de Graaff B; Jones G; Palmer AJ | |
| 2020 | Zhao T, Ahmad H, de Graaff B, Xia Q, Winzenberg T, et al., 'A systematic review of the evolution of health-economic evaluation models of osteoarthritis', Arthritis Care & Research Article accepted manuscript. ISSN 2151-464X (2020) [Refereed Article] DOI: 10.1002/acr.24410 [eCite] [Details] Co-authors: Zhao T; Ahmad H; de Graaff B; Xia Q; Winzenberg T; Palmer AJ | |
| 2020 | Zhao T, Winzenberg T, de Graaff B, Aitken D, Ahmad H, et al., 'A systematic review and meta-analysis of health state utility values for osteoarthritis-related conditions', Arthritis Care & Research ISSN 2151-464X (2020) [Refereed Article] DOI: 10.1002/acr.24478 [eCite] [Details] Citations: Scopus - 2Web of Science - 2 Co-authors: Zhao T; Winzenberg T; de Graaff B; Ahmad H; Palmer AJ | |
| 2019 | Balogun S, Winzenberg T, Wills K, Scott D, Callisaya M, et al., 'Prospective associations of osteosarcopenia and osteodynapenia with incident fracture and mortality over 10 years in community-dwelling older adults', Archives of Gerontology and Geriatrics, 82 pp. 67-73. ISSN 0167-4943 (2019) [Refereed Article] DOI: 10.1016/j.archger.2019.01.015 [eCite] [Details] Citations: Scopus - 25Web of Science - 22 Co-authors: Balogun S; Winzenberg T; Wills K; Scott D; Callisaya M; Jones G | |
| 2019 | Balogun S, Winzenberg T, Wills K, Scott DS, Jones G, et al., 'Prospective associations of low muscle mass and strength with health-related quality of life over 10-year in community-dwelling older adults', Experimental Gerontology, 118 pp. 65-71. ISSN 0531-5565 (2019) [Refereed Article] DOI: 10.1016/j.exger.2019.01.008 [eCite] [Details] Citations: Scopus - 11Web of Science - 12 Co-authors: Balogun S; Winzenberg T; Wills K; Scott DS; Jones G; Callisaya ML | |
| 2019 | Cai G, Laslett LL, Aitken D, Cicuttini F, March L, et al., 'Zoledronic acid plus methylprednisolone versus zoledronic acid or placebo in symptomatic knee osteoarthritis: a randomized controlled trial', Therapeutic Advances in Musculoskeletal Disease, 11 pp. 1-12. ISSN 1759-720X (2019) [Refereed Article] DOI: 10.1177/1759720X19880054 [eCite] [Details] Citations: Scopus - 5Web of Science - 5 Co-authors: Cai G; Laslett LL; Winzenberg T; Jones G | |
| 2019 | Cervo MM, Shivappa N, Hebert JR, Oddy WH, Winzenberg T, et al., 'Longitudinal associations between dietary inflammatory index and musculoskeletal health in community-dwelling older adults', Clinical Nutrition pp. 1-8. ISSN 0261-5614 (2019) [Refereed Article] DOI: 10.1016/j.clnu.2019.02.031 [eCite] [Details] Citations: Scopus - 28Web of Science - 25 Co-authors: Oddy WH; Winzenberg T; Balogun S; Wu F; Jones G; Scott D | |
| 2019 | Han W, Aitken D, Zheng S, Wang B, Wluka AE, et al., 'Higher serum levels of resistin are associated with knee synovitis and structural abnormalities in patients with symptomatic knee osteoarthritis', Journal of the American Medical Directors Association, 20, (10) pp. 1242-1246. ISSN 1525-8610 (2019) [Refereed Article] DOI: 10.1016/j.jamda.2019.07.001 [eCite] [Details] Citations: Scopus - 5Web of Science - 6 Co-authors: Han W; Zheng S; Zhu Z; Blizzard L; Winzenberg T; Jones G; Ding C | |
| 2019 | Mattap SM, Laslett LL, Squibb K, Wills K, Otahal P, et al., 'Hand examination, ultrasound and its association with hand pain and function in community-based older adults', Arthritis Care & Research pp. 1-28. ISSN 2151-464X (2019) [Refereed Article] DOI: 10.1002/acr.24128 [eCite] [Details] Citations: Scopus - 2 Co-authors: Mattap SM; Laslett LL; Squibb K; Wills K; Otahal P; Pan F; Winzenberg T; Jones G | |
| 2019 | Pan F, Tian J, Aitken D, Cicuttini F, Jones G, 'Pain at multiple sites is associated with prevalent and incident fractures in older adults', Journal of Bone and Mineral Research, 34, (11) pp. 2012-2018. ISSN 0884-0431 (2019) [Refereed Article] DOI: 10.1002/jbmr.3817 [eCite] [Details] Citations: Scopus - 2Web of Science - 5 Co-authors: Pan F; Tian J; Jones G | |
| 2019 | Zhai G, Pelletier J-P, Liu M, Aitken D, Randell E, et al., 'Activation of the phosphatidylcholine to lysophosphatidylcholine pathway is associated with osteoarthritis knee cartilage volume loss over time', Scientific Reports, 9, (1) Article 9648. ISSN 2045-2322 (2019) [Refereed Article] DOI: 10.1038/s41598-019-46185-w [eCite] [Details] Citations: Scopus - 23Web of Science - 24 Co-authors: Jones G | |
| 2019 | Zhu Z, Aitken D, Cicuttini F, Jones G, Ding C, 'Ambulatory activity interacts with common risk factors for osteoarthritis to modify increases in MRI-detected osteophytes', Osteoarthritis and Cartilage, 27, (4) pp. 650-658. ISSN 1063-4584 (2019) [Refereed Article] DOI: 10.1016/j.joca.2018.12.023 [eCite] [Details] Citations: Scopus - 5Web of Science - 3 Co-authors: Zhu Z; Jones G; Ding C | |
| 2018 | Aitken D, Laslett LL, Cai G, Hill C, March L, et al., 'A protocol for a multicentre, randomised, double-blind, placebo-controlled trial to compare the effect of annual infusions of zoledronic acid to placebo on knee structural change and knee pain over 24 months in knee osteoarthritis patients - ZAP2', BMC Musculoskeletal Disorders, 19, (1) Article 217. ISSN 1471-2474 (2018) [Contribution to Refereed Journal] DOI: 10.1186/s12891-018-2143-2 [eCite] [Details] Citations: Scopus - 17Web of Science - 17 Co-authors: Laslett LL; Cai G; Blizzard L; Jones G | |
| 2018 | Aitken D, Laslett LL, Pan F, Haugen IK, Otahal P, et al., 'A randomised double-blind placebo-controlled crossover trial of HUMira (adalimumab) for erosive hand OsteoaRthritis - the HUMOR trial', Osteoarthritis and Cartilage, 26, (7) pp. 880-887. ISSN 1063-4584 (2018) [Refereed Article] DOI: 10.1016/j.joca.2018.02.899 [eCite] [Details] Citations: Scopus - 69Web of Science - 66 Co-authors: Laslett LL; Pan F; Otahal P; Jones G | |
| 2018 | Balogun S, Aitken D, Winzenberg T, Wills K, Scott D, et al., 'Longitudinal associations of serum 25-hydroxyvitamin-D, physical activity, and knee pain and dysfunction with muscle loss in community-dwelling older adults', Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 73, (4) pp. 526-531. ISSN 1079-5006 (2018) [Refereed Article] DOI: 10.1093/gerona/glx157 [eCite] [Details] Citations: Scopus - 8Web of Science - 7 Co-authors: Balogun S; Winzenberg T; Wills K; Callisaya M; Jones G | |
| 2018 | Balogun S, Winzenberg T, Wills K, Scott D, Jones G, et al., 'Longitudinal associations between serum 25-hydroxyvitamin D, physical activity, knee pain and dysfunction and physiological falls risk in community-dwelling older adults', Experimental Gerontology, 104 pp. 72-77. ISSN 0531-5565 (2018) [Refereed Article] DOI: 10.1016/j.exger.2018.01.026 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Balogun S; Winzenberg T; Wills K; Jones G; Callisaya M | |
| 2018 | Cai G, Laslett LL, Aitken D, Halliday A, Pan F, et al., 'Effect of Zoledronic Acid and Denosumab in patients with low back pain and modic change: A proof-of-principle trial', Journal of Bone and Mineral Research, 33, (5) pp. 773-782. ISSN 0884-0431 (2018) [Refereed Article] DOI: 10.1002/jbmr.3376 [eCite] [Details] Citations: Scopus - 22Web of Science - 22 Co-authors: Cai G; Laslett LL; Pan F; Otahal P; Winzenberg TM; Jones G | |
| 2018 | Crisford P, Winzenberg T, Venn A, Schultz M, Aitken D, et al., 'Factors associated with physical activity promotion by allied and other non-medical health professionals: a systematic review', Patient Education and Counseling, 101, (10) pp. 1775-1785. ISSN 0738-3991 (2018) [Refereed Article] DOI: 10.1016/j.pec.2018.05.011 [eCite] [Details] Citations: Scopus - 16Web of Science - 15 Co-authors: Crisford P; Winzenberg T; Venn A; Schultz M; Cleland V | |
| 2018 | Han W, Aitken D, Zheng S, Wluka AE, Zhu Z, et al., 'Association between quantitatively measured infrapatellar fat pad high signal intensity alteration and MRI-assessed progression of knee osteoarthritis', Arthritis Care & Research pp. 1-26. ISSN 2151-464X (2018) [Refereed Article] DOI: 10.1002/acr.23713 [eCite] [Details] Citations: Scopus - 11Web of Science - 51 Co-authors: Han W; Zheng S; Zhu Z; Blizzard L; Winzenberg T; Jones G; Ding C | |
| 2018 | Mattap SM, Aitken D, Wills K, Halliday A, Ding C, et al., 'Patellar tendon enthesis abnormalities and their association with knee pain and structural abnormalities in older adults', Osteoarthritis and Cartilage, 27, (3) pp. 449-458. ISSN 1063-4584 (2018) [Refereed Article] DOI: 10.1016/j.joca.2018.11.009 [eCite] [Details] Citations: Scopus - 5Web of Science - 4 Co-authors: Mattap SM; Wills K; Ding C; Han W; Munugoda I; Jones G; Laslett LL | |
| 2018 | Mattap SM, Aitken D, Wills K, Laslett L, Ding C, et al., 'How do MRI-detected subchondral bone marrow lesions (BMLs) on two different MRI sequences correlate with clinically important outcomes?', Calcified Tissue International, 103, (2) pp. 131-143. ISSN 0171-967X (2018) [Refereed Article] DOI: 10.1007/s00223-018-0402-8 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Mattap SM; Wills K; Laslett L; Ding C; Jones G | |
| 2018 | McMillan LB, Aitken D, Ebeling P, Jones G, Scott D, 'The relationship between objectively assessed physical activity and bone health in older adults differs by sex and is mediated by lean mass', Osteoporosis International, 29, (6) pp. 1379-1388. ISSN 0937-941X (2018) [Refereed Article] DOI: 10.1007/s00198-018-4446-4 [eCite] [Details] Citations: Scopus - 9Web of Science - 10 Co-authors: Jones G; Scott D | |
| 2018 | Munugoda IP, Wills K, Cicuttini F, Graves SE, Lorimer M, et al., 'The association between ambulatory activity, body composition and hip or knee joint replacement due to osteoarthritis: a prospective cohort study', Osteoarthritis and Cartilage, 26, (5) pp. 671-679. ISSN 1063-4584 (2018) [Refereed Article] DOI: 10.1016/j.joca.2018.02.895 [eCite] [Details] Citations: Scopus - 16Web of Science - 15 Co-authors: Munugoda IP; Wills K; Jones G; Callisaya ML | |
| 2018 | Pan F, Tian J, Aitken D, Cicuttini F, Jones G, 'Predictors of pain severity trajectory in older adults: a 10.7-year follow-up study', Osteoarthritis and Cartilage, 26, (12) pp. 1619-1626. ISSN 1063-4584 (2018) [Refereed Article] DOI: 10.1016/j.joca.2018.08.002 [eCite] [Details] Citations: Scopus - 22Web of Science - 24 Co-authors: Pan F; Tian J; Jones G | |
| 2018 | Pan F, Tian J, Cicuttini F, Jones G, Aitken D, 'Differentiating knee pain phenotypes in older adults: a prospective cohort study', Rheumatology, 58, (2) pp. 274-283. ISSN 1462-0324 (2018) [Refereed Article] DOI: 10.1093/rheumatology/key299 [eCite] [Details] Citations: Scopus - 4Web of Science - 6 Co-authors: Pan F; Tian J; Jones G | |
| 2018 | Thompson MJW, Jones G, Aitken DA, 'Constitutive melanin density is associated with higher 25-hydroxyvitamin D and potentially total body BMD in older Caucasian adults via increased sun tolerance and exposure', Osteoporosis International, 29, (8) pp. 1887-1895. ISSN 0937-941X (2018) [Refereed Article] DOI: 10.1007/s00198-018-4568-8 [eCite] [Details] Citations: Scopus - 5Web of Science - 4 Co-authors: Thompson MJW; Jones G | |
| 2018 | Wu F, Xiao C, Aitken D, Jones G, Winzenberg T, 'The optimal dosage regimen of vitamin D supplementation for correcting deficiency in adolescents: a pilot randomized controlled trial', European Journal of Clinical Nutrition, 72, (4) pp. 534-540. ISSN 0954-3007 (2018) [Refereed Article] DOI: 10.1038/s41430-018-0098-x [eCite] [Details] Citations: Scopus - 8Web of Science - 5 Co-authors: Wu F; Xiao C; Jones G; Winzenberg T | |
| 2018 | Zheng S, Tu L, Cicuttini F, Han W, Zhu Z, et al., 'Effect of vitamin D supplementation on depressive symptoms in patients with knee osteoarthritis', Journal of The American Medical Directors Association pp. 1-7. ISSN 1525-8610 (2018) [Refereed Article] DOI: 10.1016/j.jamda.2018.09.006 [eCite] [Details] Citations: Scopus - 14Web of Science - 15 Co-authors: Zheng S; Han W; Zhu Z; Antony B; Winzenberg T; Blizzard L; Jones G; Ding C | |
| 2018 | Zheng S, Wang B, Han W, Zhu Z, Wang X, et al., 'Vitamin D supplementation and inflammatory and metabolic biomarkers in patients with knee osteoarthritis: post hoc analysis of a randomised controlled trial', British Journal of Nutrition, 120, (1) pp. 41-48. ISSN 0007-1145 (2018) [Refereed Article] DOI: 10.1017/S0007114518001174 [eCite] [Details] Citations: Scopus - 14Web of Science - 14 Co-authors: Zheng S; Han W; Zhu Z; Jin X; Antony B; Winzenberg T; Blizzard L; Jones G; Ding C | |
| 2017 | Ahedi HG, Aspden RM, Blizzard LC, Saunders FR, Cicuttini FM, et al., 'Hip shape as a predictor of osteoarthritis progression in a prospective population cohort', Arthritis Care & Research, 69, (10) pp. 1566-1573. ISSN 2151-4658 (2017) [Refereed Article] DOI: 10.1002/acr.23166 [eCite] [Details] Citations: Scopus - 25Web of Science - 24 Co-authors: Ahedi HG; Blizzard LC; Jones G | |
| 2017 | Balogun S, Winzenberg T, Wills K, Scott D, Jones G, et al., 'Prospective associations of low muscle mass and function with 10-year falls risk, incident fracture and mortality in community-dwelling older adults', Journal of Nutrition, Health and Aging, 21, (7) pp. 843-848. ISSN 1279-7707 (2017) [Refereed Article] DOI: 10.1007/s12603-016-0843-6 [eCite] [Details] Citations: Scopus - 69Web of Science - 67 Co-authors: Balogun S; Winzenberg T; Wills K; Jones G; Callisaya ML | |
| 2017 | Pan F, Tian J, Aitken D, Cicuttini F, Winzenberg T, et al., 'The association of knee structural pathology with pain at the knee is modified by pain at other sites in those with knee osteoarthritis', Clinical Rheumatology, 36, (11) pp. 2549-2555. ISSN 0770-3198 (2017) [Refereed Article] DOI: 10.1007/s10067-017-3838-8 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Pan F; Tian J; Winzenberg T; Jones G | |
| 2017 | Thompson MJW, Aitken DA, Otahal P, Cicolini J, Winzenberg TM, et al., 'The relationship between cumulative lifetime ultraviolet radiation exposure, bone mineral density, falls risk and fractures in older adults', Osteoporosis International, 28, (7) pp. 2061-2068. ISSN 0937-941X (2017) [Refereed Article] DOI: 10.1007/s00198-017-4001-8 [eCite] [Details] Citations: Scopus - 10Web of Science - 9 Co-authors: Thompson MJW; Otahal P; Winzenberg TM; Jones G | |
| 2017 | Thompson MJW, Aitken DA, van der Mei IA, Otahal P, Cicolini J, et al., 'Predictors of Beagley-Gibson skin cast grade in older adults', Skin Research and Technology, 23, (2) pp. 235-242. ISSN 0909-752X (2017) [Refereed Article] DOI: 10.1111/srt.12328 [eCite] [Details] Citations: Scopus - 7Web of Science - 7 Co-authors: Thompson MJW; van der Mei IA; Otahal P; Winzenberg TM; Jones G | |
| 2017 | Zheng S, Jin X, Cicuttini F, Wang X, Zhu Z, et al., 'Maintaining vitamin D sufficiency is associated with improved structural and symptomatic outcomes in knee osteoarthritis', American Journal of Medicine, 130, (10) pp. 1211-1218. ISSN 0002-9343 (2017) [Refereed Article] DOI: 10.1016/j.amjmed.2017.04.038 [eCite] [Details] Citations: Scopus - 25Web of Science - 19 Co-authors: Zheng S; Jin X; Zhu Z; Han W; Winzenberg T; Antony B; Blizzard L; Jones G; Ding C | |
| 2016 | Ahedi HG, Aitken DA, Blizzard LC, Ding CH, Cicuttini FM, et al., 'Correlates of Hip Cartilage Defects: A Cross-sectional Study in Older Adults', Journal of Rheumatology, 43, (7) pp. 1406-1412. ISSN 0315-162X (2016) [Refereed Article] DOI: 10.3899/jrheum.151001 [eCite] [Details] Citations: Scopus - 12Web of Science - 12 Co-authors: Ahedi HG; Blizzard LC; Ding CH; Jones G | |
| 2016 | Foong YC, Chherawala N, Aitken D, Scott D, Winzenberg T, et al., 'Accelerometer-determined physical activity, muscle mass, and leg strength in community-dwelling older adults', Journal of Cachexia, Sarcopenia and Muscle, 7, (3) pp. 275-283. ISSN 2190-6009 (2016) [Refereed Article] DOI: 10.1002/jcsm.12065 [eCite] [Details] Citations: Scopus - 67 Co-authors: Foong YC; Winzenberg T; Jones G | |
| 2016 | Han W, Aitken D, Zhu Z, Halliday A, Wang X, et al., 'Signal intensity alteration in the infrapatellar fat pad at baseline for the prediction of knee symptoms and structure in older adults: a cohort study', ARD Online, 75 pp. 1783-1788. ISSN 1468-2060 (2016) [Refereed Article] DOI: 10.1136/annrheumdis-2015-208360 [eCite] [Details] Citations: Scopus - 47Web of Science - 50 Co-authors: Han W; Zhu Z; Antony B; Jones G; Ding C | |
| 2016 | Han W, Aitken D, Zhu Z, Halliday A, Wang X, et al., 'Hypointense signals in the infrapatellar fat pad assessed by magnetic resonance imaging are associated with knee symptoms and structure in older adults: a cohort study', Arthritis Research & Therapy, 18, (1) Article 234. ISSN 1478-6362 (2016) [Refereed Article] DOI: 10.1186/s13075-016-1130-y [eCite] [Details] Citations: Scopus - 24Web of Science - 23 Co-authors: Han W; Zhu Z; Antony B; Jones G; Ding C | |
| 2016 | Hill CL, March LM, Aitken D, Lester SE, Battersby R, et al., 'Fish oil in knee osteoarthritis: a randomised clinical trial of low dose versus high dose', Annals of the Rheumatic Diseases, 75, (1) pp. 23-29. ISSN 1468-2060 (2016) [Refereed Article] DOI: 10.1136/annrheumdis-2014-207169 [eCite] [Details] Citations: Scopus - 75Web of Science - 65 Co-authors: Hynes K; Jones G | |
| 2016 | Johnson LG, Butson ML, Polman RC, Raj IS, Borkoles E, et al., 'Light physical activity is positively associated with cognitive performance in older community dwelling adults', Journal of Science and Medicine in Sport, 19, (11) pp. 877-882. ISSN 1440-2440 (2016) [Refereed Article] DOI: 10.1016/j.jsams.2016.02.002 [eCite] [Details] Citations: Scopus - 36Web of Science - 33 Co-authors: Jones G | |
| 2016 | Khan HI, Aitken D, Ding C, Blizzard L, Pelletier JP, et al., 'Natural history and clinical significance of meniscal tears over 8 years in a midlife cohort', BMC Musculoskeletal Disorders, 17 Article 4. ISSN 1471-2474 (2016) [Refereed Article] DOI: 10.1186/s12891-015-0862-1 [eCite] [Details] Citations: Scopus - 15Web of Science - 13 Co-authors: Khan HI; Ding C; Blizzard L; Jones G | |
| 2016 | Khan HI, Chou L, Aitken D, McBride A, Ding C, et al., 'Correlation between changes in global knee structures assessed on Magnetic Resonance Imaging and radiographic osteoarthritis changes over 10 years in a mid-life cohort', Arthritis Care & Research, 68, (7) pp. 958-964. ISSN 2151-4658 (2016) [Refereed Article] DOI: 10.1002/acr.22778 [eCite] [Details] Citations: Scopus - 5Web of Science - 3 Co-authors: Khan HI; McBride A; Ding C; Blizzard L; Jones G | |
| 2016 | McBride A, Khan HI, Aitken D, Chou L, Ding C, et al., 'Does cartilage volume measurement or radiographic osteoarthritis at baseline independently predict ten-year cartilage volume loss?', BMC Musculoskeletal Disorders, 17 Article 54. ISSN 1471-2474 (2016) [Refereed Article] DOI: 10.1186/s12891-016-0900-7 [eCite] [Details] Citations: Scopus - 3Web of Science - 4 Co-authors: McBride A; Khan HI; Ding C; Blizzard L; Jones G | |
| 2016 | Zhang W, Sun G, Aitken D, Likhodii S, Liu M, et al., 'Lysophosphatidylcholines to phosphatidylcholines ratio predicts advanced knee osteoarthritis', Rheumatology, 55, (9) pp. 1566-1574. ISSN 1462-0324 (2016) [Refereed Article] DOI: 10.1093/rheumatology/kew207 [eCite] [Details] Citations: Scopus - 51Web of Science - 52 Co-authors: Jones G; Zhai G | |
| 2015 | Aitken D, Buchbinder R, Jones G, Winzenberg T, 'Interventions to improve adherence to exercise for chronic musculoskeletal pain in adults', Australian Family Physician, 44, (1-2) pp. 39-42. ISSN 0300-8495 (2015) [Refereed Article] Citations: Web of Science - 21 Co-authors: Jones G; Winzenberg T | |
| 2015 | Khan HI, Aitken D, Blizzard L, Ding C, Pelletier J-P, et al., 'History of knee injury and MRI-assessed knee structures in middle- and older-aged adults: a cross-sectional study', Clinical Rheumatology, 34 pp. 1463-1472. ISSN 1434-9949 (2015) [Refereed Article] DOI: 10.1007/s10067-014-2758-0 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 Co-authors: Khan HI; Blizzard L; Ding C; Jones G | |
| 2015 | Khan HI, Aitken D, Chou L, McBride A, Ding C, et al., 'A family history of knee joint replacement increases the progression of knee radiographic osteoarthritis and medial tibial cartilage volume loss over 10 years', Osteoarthritis and Cartilage, 23, (2) pp. 203-209. ISSN 1063-4584 (2015) [Refereed Article] DOI: 10.1016/j.joca.2014.11.016 [eCite] [Details] Citations: Scopus - 16Web of Science - 15 Co-authors: Khan HI; McBride A; Ding C; Blizzard L; Jones G | |
| 2015 | Khan HI, Aitken D, Chou L, McBride AP, Ding C, et al., 'Reply Letter to the Editor: Knee joint replacement and individual susceptibility for progression of knee osteoarthritis and tibial cartilage volume loss: not only genes run in the family', Osteoarthritis and Cartilage: Journal of The Osteoarthritis Research Society International, 23, (10) pp. 1819-20. ISSN 1063-4584 (2015) [Letter or Note in Journal] DOI: 10.1016/j.joca.2015.05.031 [eCite] [Details] Co-authors: Khan HI; McBride AP; Ding C; Blizzard CL; Jones Graeme | |
| 2015 | Scott D, Ebeling PR, Sanders KM, Aitken D, Winzenberg T, et al., 'Vitamin D and physical activity status: Associations with five-year changes in body composition and muscle function in community-dwelling older adults', Journal of Clinical Endocrinology and Metabolism, 100, (2) pp. 670-678. ISSN 1945-7197 (2015) [Refereed Article] DOI: 10.1210/jc.2014-3519 [eCite] [Details] Citations: Scopus - 25Web of Science - 25 Co-authors: Winzenberg T; Jones G | |
| 2014 | Ahedi H, Aitken D, Blizzard L, Cicuttini F, Jones G, 'A population-based study of the association between hip bone marrow lesions, high cartilage signal, and hip and knee pain', Clinical Rheumatology, 33, (3) pp. 369-376. ISSN 1434-9949 (2014) [Refereed Article] DOI: 10.1007/s10067-013-2394-0 [eCite] [Details] Citations: Scopus - 17Web of Science - 16 Co-authors: Ahedi H; Blizzard L; Jones G | |
| 2014 | Ahedi HK, Aitken D, Scott D, Blizzard L, Cicuttini F, et al., 'The Association Between Hip Muscle Cross-Sectional Area, Muscle Strength, and Bone Mineral Density', Calcified Tissue International, 95, (1) pp. 64-72. ISSN 1432-0827 (2014) [Refereed Article] DOI: 10.1007/s00223-014-9863-6 [eCite] [Details] Citations: Scopus - 24Web of Science - 20 Co-authors: Ahedi HK; Blizzard L; Jones G | |
| 2014 | Aitken D, Ding C, Pelletier JP, Martel-Pelletier J, Cicuttini F, et al., 'Responsiveness of Magnetic Resonance Imaging-derived Measures Over 2.7 Years', Journal of Rheumatology, 41, (10) pp. 2060-2067. ISSN 0315-162X (2014) [Refereed Article] DOI: 10.3899/jrheum.130953 [eCite] [Details] Citations: Scopus - 7Web of Science - 7 Co-authors: Ding C; Jones G | |
| 2014 | Cao Y, Stannus OP, Aitken D, Cicuttini F, Antony B, et al., 'Cross-sectional and longitudinal associations between systemic, subchondral bone mineral density and knee cartilage thickness in older adults with or without radiographic osteoarthritis', Annals of the Rheumatic Diseases: The Euler Journal, 73, (11) pp. 2003-2009. ISSN 1468-2060 (2014) [Refereed Article] DOI: 10.1136/annrheumdis-2013-203691 [eCite] [Details] Citations: Scopus - 36Web of Science - 31 Co-authors: Cao Y; Stannus OP; Antony B; Jones G; Ding C | |
| 2014 | Foong YC, Aitken D, Winzenberg T, Otahal P, Scott D, et al., 'The association between physical activity and reduced body fat lessens with age - Results from a cross-sectional study in community-dwelling older adults', Experimental Gerontology, 55 pp. 107-112. ISSN 0531-5565 (2014) [Refereed Article] DOI: 10.1016/j.exger.2014.04.006 [eCite] [Details] Citations: Scopus - 24Web of Science - 24 Co-authors: Foong YC; Winzenberg T; Otahal P; Jones G | |
| 2014 | Foong YC, Khan HI, Blizzard L, Ding C, Cicuttini F, et al., 'The clinical significance, natural history and predictors of bone marrow lesion change over eight years', Arthritis Research & Therapy, 16, (4) Article R149. ISSN 1478-6362 (2014) [Refereed Article] DOI: 10.1186/ar4611 [eCite] [Details] Citations: Scopus - 20Web of Science - 20 Co-authors: Foong YC; Khan HI; Blizzard L; Ding C; Jones G | |
| 2014 | Goldsmith GM, Aitken D, Cicuttini FM, Wluka AE, Winzenberg T, et al., 'Osteoarthritis bone marrow lesions at the knee and large artery characteristics', Osteoarthritis and Cartilage, 22, (1) pp. 91-94. ISSN 1063-4584 (2014) [Refereed Article] DOI: 10.1016/j.joca.2013.10.022 [eCite] [Details] Citations: Scopus - 11Web of Science - 11 Co-authors: Goldsmith GM; Winzenberg T; Ding CH; Jones G; Sharman JE | |
| 2014 | Han W, Cai S, Liu Z, Jin X, Wang X, et al., 'Infrapatellar fat pad in the knee: Is local fat good or bad for knee osteoarthritis?', Arthritis Research & Therapy, 16, (4) Article R145. ISSN 1478-6362 (2014) [Refereed Article] DOI: 10.1186/ar4607 [eCite] [Details] Citations: Scopus - 67Web of Science - 62 Co-authors: Han W; Liu Z; Jin X; Antony B; Cao Y; Jones G; Ding C | |
| 2014 | Scott D, Hayes A, Sanders KM, Aitken D, Ebeling PR, et al., 'Operational definitions of sarcopenia and their associations with 5-year changes in falls risk in community-dwelling middle-aged and older adults', Osteoporosis International, 25, (1) pp. 187-193. ISSN 1433-2965 (2014) [Refereed Article] DOI: 10.1007/s00198-013-2431-5 [eCite] [Details] Citations: Scopus - 95Web of Science - 91 Co-authors: Jones G | |
| 2014 | Scott D, Sanders KM, Aitken D, Hayes A, Ebeling PR, et al., 'Sarcopenic obesity and dynapenic obesity: 5-year associations with falls risk in middle-aged and older adults', Obesity: a research journal, 22, (6) pp. 1568-1574. ISSN 1930-7381 (2014) [Refereed Article] DOI: 10.1002/oby.20734 [eCite] [Details] Citations: Scopus - 74Web of Science - 71 Co-authors: Jones G | |
| 2013 | Ahedi H, Aitken D, Blizzard L, Cicuttini F, Jones G, 'The association between hip bone marrow lesions and bone mineral density: a cross-sectional and longitudinal population-based study', Osteoarthritis and Cartilage, 21, (10) pp. 1545-1549. ISSN 1063-4584 (2013) [Refereed Article] DOI: 10.1016/j.joca.2013.06.002 [eCite] [Details] Citations: Scopus - 6Web of Science - 8 Co-authors: Ahedi H; Blizzard L; Jones G | |
| 2013 | Dore DA, Winzenberg TM, Ding C, Otahal P, Pelletier JP, et al., 'The association between objectively measured physical activity and knee structural change using MRI', Annals of the Rheumatic Diseases, 72, (7) pp. 1170-1175. ISSN 0003-4967 (2013) [Refereed Article] DOI: 10.1136/annrheumdis-2012-201691 [eCite] [Details] Citations: Scopus - 75Web of Science - 76 Co-authors: Winzenberg TM; Ding C; Otahal P; Jones G | |
| 2013 | Khan HI, Aitken D, Zhai G, Ding C, Pelletier J-P, et al., 'Association between hip and knee cartilage measured using radiographs and magnetic resonance imaging: the Tasmanian Older Adult Cohort Study', Rheumatology, 52, (11) pp. 2009-2015. ISSN 0080-2727 (2013) [Refereed Article] DOI: 10.1093/rheumatology/ket243 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 Co-authors: Khan HI; Ding C; Blizzard L; Jones G | |
| 2012 | Dore D, De Hoog J, Giles G, Ding C, Cicuttini F, et al., 'A longitudinal study of the association between dietary factors, serum lipids, and bone marrow lesions of the knee', Arthritis Research & Therapy, 14, (1) Article R13. ISSN 1478-6362 (2012) [Refereed Article] DOI: 10.1186/ar3689 [eCite] [Details] Citations: Scopus - 31Web of Science - 28 Co-authors: De Hoog J; Ding C; Jones G | |
| 2012 | Laslett LL, Dore DA, Quinn SJ, Boon P, Ryan E, et al., 'Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial', Annals of the Rheumatic Diseases, 71, (8) pp. 1322-1328. ISSN 0003-4967 (2012) [Refereed Article] DOI: 10.1136/annrheumdis-2011-200970 [eCite] [Details] Citations: Scopus - 200Web of Science - 181 Co-authors: Laslett LL; Boon P; Winzenberg TM; Jones G | |
| 2012 | Van der Mei IAF, Dore D, Winzenberg T, Blizzard L, Jones G, 'Vitamin D deficiency in Tasmania: A whole of life perspective', Internal Medicine Journal, 42, (10) pp. 1137-1144. ISSN 1444-0903 (2012) [Refereed Article] DOI: 10.1111/j.1445-5994.2012.02788.x [eCite] [Details] Citations: Scopus - 9Web of Science - 8 Co-authors: Van der Mei IAF; Winzenberg T; Blizzard L; Jones G | |
| 2011 | Jones G, Schultz MG, Dore D, 'Physical Activity and Osteoarthritis of the Knee: Can MRI Scans Shed More Light on This Issue?', The Physician and Sportsmedicine: A Peer Reviewed Journal of Medical Aspects of Sports, Exercise and Fitness, 39, (3) pp. 55-61. ISSN 0091-3847 (2011) [Refereed Article] DOI: 10.3810/psm.2011.09.1921 [eCite] [Details] Citations: Scopus - 7Web of Science - 5 Co-authors: Jones G; Schultz MG | |
| 2010 | Dore D, Ding C, Winzenberg T, Cicuttini F, Jones G, 'Reply to letter by Hayashi et al. commenting on choice of pulse sequences for MRI based semi-quantitative assessment of cartilage defects ', Arthritis & Rheumatism, 62, (12) pp. 3831-3832. ISSN 0004-3591 (2010) [Letter or Note in Journal] DOI: 10.1002/art.27730 [eCite] [Details] Citations: Scopus - 7Web of Science - 6 Co-authors: Ding C; Winzenberg T; Jones G | |
| 2010 | Dore D, Martens A, Quinn S, Ding C, Winzenberg T, et al., 'Bone marrow lesions predict site-specific cartilage defect development and volume loss: a prospective study in older adults', Arthritis Research & Therapy, 12, (6) EJ ISSN 1478-6354 (2010) [Refereed Article] DOI: 10.1186/ar3209 [eCite] [Details] Citations: Scopus - 77Web of Science - 71 Co-authors: Martens A; Quinn S; Ding C; Winzenberg T; Jones G | |
| 2010 | Dore D, Quinn S, Ding C, Winzenberg T, Cicuttini F, et al., 'Subchondral Bone and Cartilage Damage - A Prospective Study in Older Adults', Arthritis and Rheumatism, 62, (7) pp. 1967-1973. ISSN 0004-3591 (2010) [Refereed Article] DOI: 10.1002/art.27467 [eCite] [Details] Citations: Scopus - 52Web of Science - 49 Co-authors: Quinn S; Ding C; Winzenberg T; Jones G | |
| 2010 | Dore D, Quinn S, Ding C, Winzenberg T, Zhai G, et al., 'Natural history and clinical significance of MRI-detected bone marrow lesions at the knee: a prospective study in community dwelling older adults', Arthritis Research & Therapy, 12, (6) EJ ISSN 1478-6354 (2010) [Refereed Article] DOI: 10.1186/ar3210 [eCite] [Details] Citations: Scopus - 110Web of Science - 98 Co-authors: Quinn S; Ding C; Winzenberg T; Jones G | |
| 2010 | Stannus OP, Jones G, Quinn SJ, Cicuttini FM, Dore D, et al., 'The association between leptin, interleukin-6, and hip radiographic osteoarthritis in older people: a cross-sectional study', Arthritis Research & Therapy, 12, (3) EJ ISSN 1478-6354 (2010) [Refereed Article] DOI: 10.1186/ar3022 [eCite] [Details] Citations: Scopus - 59Web of Science - 54 Co-authors: Stannus OP; Jones G; Quinn SJ; Ding C | |
| 2009 | Dore D, Quinn S, Ding C, Winzenberg T, Jones G, 'Correlates of Subchondral BMD: A Cross-Sectional Study', Journal of Bone and Mineral Research, 24, (12) pp. 2007-2015. ISSN 0884-0431 (2009) [Refereed Article] DOI: 10.1359/JBMR.090532 [eCite] [Details] Citations: Scopus - 42Web of Science - 40 Co-authors: Quinn S; Ding C; Winzenberg T; Jones G | |
| 2008 | Dore D, Ding C, Jones G, 'A pilot study of the reproducibility and validity of measuring knee subchondral bone density in the tibia', Osteoarthritis and Cartilage, 16, (12) pp. 1539-1544. ISSN 1063-4584 (2008) [Refereed Article] DOI: 10.1016/j.joca.2008.04.012 [eCite] [Details] Citations: Scopus - 20Web of Science - 18 Co-authors: Ding C; Jones G |
Review
(1 outputs)| Year | Citation | Altmetrics |
|---|---|---|
| 2010 | Van der Mei IAF, Dore D, 'Vitamin D supplementation in infants', Report for the Tasmanian Department of Health and Human Services (2010) [Substantial Review] Co-authors: Van der Mei IAF |
Conference Publication
(7 outputs)| Year | Citation | Altmetrics |
|---|---|---|
| 2020 | Aitken D, Humphries D, Laslett L, Pitchford N, Khan HI, et al., 'Magnetic resonance imaging (MRI)-assessed knee abnormalities in Australian rules football players - AFL tas knee study', Osteoarthritis and Cartilage ISSN 1063-4584 (2020) [Conference Extract] Co-authors: Laslett L; Pitchford N; Khan HI; Jones G; Winzenberg T | |
| 2018 | Pan F, Tian J, Aitken D, Cicuttini F, Jones G, 'Pain at multiple sites is associated with prevalent and incident fractures in older adults: a 5.1-year follow-up study', Journal of Bone and Mineral Research, ASBMR Annual Meeting 2018, September - October, Montreal, Canada ISSN 0884-0431 (2018) [Conference Extract] Co-authors: Pan F; Tian J; Jones G | |
| 2017 | Foong Y, Aitken D, Humphries D, Laslett L, Pitchford N, et al., 'Knee function, pain and magnetic resonance imaging abnormalities in Australian Rules Football players: a cohort study', Internal Medicine Journal ISSN 1444-0903 (2017) [Conference Extract] DOI: 10.1111/imj.5_13463 [eCite] [Details] Co-authors: Foong Y; Laslett L; Pitchford N; Khan H; Jones G; Winzenberg T | |
| 2017 | Pan F, Tian J, Aitken D, Cicuttini F, Ding C, et al., 'Characterizing and validating the phenotype of knee pain: a latent class analysis', Annals of the Rheumatic Diseases, pp. 471, June. ISSN 0003-4967 (2017) [Conference Extract] DOI: 10.1136/annrheumdis-2017-eular.3033 [eCite] [Details] Co-authors: Pan F; Tian J; Ding C; Jones G | |
| 2016 | Pan F, Aitken D, Tian J, Cicuttini FM, Ding C, et al., 'Which factors associate with localized knee pain and generalized pain: A 10-year longitudinal study?', Arthritis & Rheumatology, pp. 1, Vol 68, (suppl 10). ISSN 2326-5191 (2016) [Conference Extract] Co-authors: Pan F; Tian J; Ding C; Jones G | |
| 2009 | Dore D, Ding C, Jones G, 'Natural history of areal bone marrow lesions', Osteoarthritis and Cartilage, Osteoarthritis Research Society International, September, Montreal, Canada, pp. S40-S40. (2009) [Conference Extract] Co-authors: Ding C; Jones G | |
| 2009 | Dore D, Ding C, Jones G, 'Which subchondral bone measure is the best predictor of cartilage damage?', Bone, pp. S144. (2009) [Conference Extract] Co-authors: Ding C; Jones G |
Entry
(1 outputs)| Year | Citation | Altmetrics |
|---|---|---|
| 2020 | Aitken D, Jones G, Winzenberg T, 'Clinical overview of osteoarthritis (OA) and the challenges faced for future management', Encyclopedia of Biomedical Gerontology, SIS Rattan (ed), 1, pp. 420-430 (2020) [Entry] DOI: 10.1016/B978-0-12-801238-3.11419-9 [eCite] [Details] Citations: Scopus - 3 Co-authors: Jones G; Winzenberg T |
Grants & Funding
Funding Summary
Number of grants
23
Total funding
Projects
- Description
- The primary aim of this study is to work with GPs to co-design interventions to increase referral rates of people with osteoarthritis to GLA:D / exercise therapy. The co-designed intervention will be piloted and implemented in a future cluster-randomised controlled trial (RCT) to increase GP referral rates to exercise therapy. This study is a component of a large project that aims to provide high-value care for Tasmanians with osteoarthritis
- Funding
- ANZMUSC/ANZBACK CRE ($18,109)
- Scheme
- Grant-Seed
- Administered By
- University of Tasmania
- Research Team
- Balogun S; Aitken D; Barton C; Ezzat A; Lawler K; Winzenberg TM; Mulford J
- Year
- 2023
- Description
- Limited literature search to update the existing literature review for the Hip Fracture Care and Osteoarthritis of the Knee Clinical Care Standards (that we conducted in 2020).
- Funding
- KP Health ($86,000)
- Scheme
- Consultancy
- Administered By
- University of Tasmania
- Research Team
- Winzenberg TM; Aitken D; Makin JK; Scheepers EJ
- Year
- 2022
- Description
- GLA:D is an international evidence-based education and exercise program for people with knee and hip osteoarthritis. This project will evaluate the implementation of GLA:D through the RHH physiotherapy community outpatient clinics for patients on a joint replacement surgery pathway. It will benefit patients and potentially reduce pressure on elective surgery waiting lists.
- Funding
- Royal Hobart Hospital Research Foundation ($24,943)
- Scheme
- Grant-Project
- Administered By
- University of Tasmania
- Research Team
- Aitken D; Lawler K; Harvie P; O'Brien L; Barton C; Hyland P; de Graaff B; Van Dam PJ; Peterson GM; Collins N; Jones G
- Year
- 2022
- Description
- Donation for "Improving access to high-value care for osteoarthritis: IMPACT-TAS"
- Funding
- Donation via University of Tasmania Foundation ($78,465)
- Scheme
- Donation - Individual
- Administered By
- University of Tasmania
- Research Team
- Winzenberg TM; Aitken D
- Year
- 2021
- Description
- Conduct limited scope evidence-based literature reviews to inform the Australia Commission on Safety and Quality in Health Care's review of the Hip Fracture Care and Osteoarthritis of the Knee Clinical Care Standards.
- Funding
- KP Health ($35,000)
- Scheme
- Consultancy
- Administered By
- University of Tasmania
- Research Team
- Winzenberg TM; Makin JK; Aitken D
- Year
- 2020
- Description
- This prospective, observational study will recruit patients undergoing primary elective hip or knee joint replacement at study sites in Tasmania. Participants will complete patient reported outcome measure (PROMs) surveys and have accelerometry data collected preoperatively and at 6 weeks, 12 weeks, 6 months and 12 months post-operatively. The trajectory of their recovery is measured both by their subjective PROMs responses and objective movement data captured by accelerometry to provide insights into expected performance changes and evaluate PROMs characteristics.The project aims to quantify physical performance changes that occur in patients following hip or knee arthroplasty and compare the relationship between this objective data and subjective PROMs.
- Funding
- The MPST Foundation Ltd ($12,940)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Aitken D; Laslett LL; Harvie P; Haward CP
- Year
- 2020
- Funding
- National Health & Medical Research Council ($114,033)
- Scheme
- Scholarship-Postgraduate
- Administered By
- University of Tasmania
- Research Team
- Aitken D; Thompson M
- Period
- 2019 - 2023
- Grant Reference
- GNT1168209
- Description
- Knee osteoarthritis (OA) is common, but the current treatments are poor. Almost 60% of people with knee OA have joint inflammation. Patients with inflammation are more likely to experience joint pain and rapid joint destruction. We propose that treating patients with inflammatory knee OA with the anti-inflammatory drug, diacerein, will reduce pain and joint damage.
- Funding
- National Health & Medical Research Council ($1,309,503)
- Collaborators
- Monash University ($150,970); University of Adelaide ($231,143); University of Western Australia ($168,151)
- Scheme
- Grant-Project
- Administered By
- University of Tasmania
- Research Team
- Aitken D; Jones G; Cicuttini FM; Winzenberg TM; Keen H
- Period
- 2018 - 2022
- Grant Reference
- 1147370
- Funding
- Medical Research Future Fund ($431,000)
- Scheme
- Fellowship-Career Development
- Administered By
- University of Tasmania
- Research Team
- Aitken D
- Period
- 2018 - 2021
- Description
- This project will implement a community walking group for patients with knee osteoarthritis. This pilot study aims to evaluate the feasibility of recruitment, retention, randomisation and the implementation of a RCT aimed to examine the effect walking has on knee structure (assessed using advanced magnetic resonance imaging (MRI) technology). We will recruit 48 participants with knee osteoarthritis who will be randomised to either a 6-month community walking group or a usual care (control) group. Participants in the walking group will train 3 days per week for 1 hour each day. Walking will be performed at a moderate intensity (50-70% of each participant's heart rate reserve). This frequency/intensity is recommended for Australian adults (Australian National Physical Activity Guidelines) and for adults with knee osteoarthritis (Arthritis Australia). The structure of our program is based on a group walking protocol which showed improvement in pain in knee osteoarthritis patients. The walking program will be supervised by accredited physiotherapists with experience in prescribing exercise for knee osteoarthritis patients. Each group walking session will consist of:*10 min warm up consisting of slow walking and calisthenics: arm circles, trunk rotation, shoulder and chest stretches, and side stretch.*40 min group walking phase where participants are encouraged to walk at 50-70% of their heart rate reserve as determined from an exercise treadmill test at the start of the study. *10 min cool down consisting of slow walking and flexibility exercises. Participants randomised to usual care will receive usual standard care from their medical practitioner, as well as generic information about knee osteoarthritis. This will the control group, and this is required in order to examine the true effect walking has on knee health.
- Funding
- Arthritis Australia ($30,000)
- Scheme
- Grant-Project
- Administered By
- University of Tasmania
- Research Team
- Aitken D; Jones G; Callisaya M; Balogun S
- Year
- 2018
- Description
- During the course of my CDF Fellowship I am leading five innovative research projects that aim to provide clinically translatable evidence offering new effective treatments that improve outcomes for patients with musculoskeletal diseases. Four out of the five research projects are funded either by NHMRC or industry. I am applying for the ASBMR Rising Star award to fund part of the fifth project in my research program: Do osteoporosis therapies work for back pain? We will recruit 125 patients with chronic low back pain patients. Men and women will be recruited if they are >34 years of age, have at least moderate back pain (≥40/100 on 100mm VAS) for at least 3 months, and have type 1, type 2 or mixed type Modic changes on MRI (same inclusion criteria in MODIC1). Exclusion criteria include: Neuropathic pain component is unclear/definite (painDETECT questionnaire13 score ≥12, based on MODIC1 findings); Diagnosis of a centrally mediated pain phenotype (e.g. fibromyalgia); Prior use of denosumab or bisphosphonates; Serum 25-hydroxyvitamin D concentrations < 40 nmol/L; Pregnancy or breastfeeding; Prior cancer diagnosis; Poor dental fitness; Use of high doses of opiate pain medication (equivalent to oxycontin ≥80mg/day); Leg pain is of greater severity than back pain; Back surgery within the last 5 years.Eligible participants will receive one subcutaneous injection of denosumab (60mg in 1ml saline) or 1ml saline every 6 months for 24 months (0, 6, 12, 18 months).
- Funding
- American Society for Bone and Mineral Research ($82,000)
- Scheme
- Grant-Rising Star Award
- Administered By
- University of Tasmania
- Research Team
- Aitken D
- Year
- 2018
- Description
- Participating in PA reduces pain and improves function in people with KOA. Despite this, people with KOA are alarmingly inactive. It is, therefore, of high priority to identify effective, low-cost and sustainable PA promotion strategies for KOA. parkrun is an international movement of weekly 5 km walk/run events held in public spaces. Parkrun has a broad appeal to various population groups including non-athletes, however no previous reports had evaluated parkrun as a promising PA promotion setting for KOA. Our study will determine the feasibility, acceptability and safety of parkrun as a novel strategy to promote PA for people with KOA.
- Funding
- Medibank Better Health Foundation ($31,313)
- Scheme
- Grant - Project Grant Funding
- Administered By
- University of Tasmania
- Research Team
- Aitken D; Lahham A; Jose KA; Cleland V; Jones G; Winzenberg TM; Grunseit A
- Period
- 2018 - 2019
- Description
- Osteoarthritis is a leading cause of pain and disability among older people and there is currently no cure. In recent years, there has been increasing concern about the discrepancies between care provided by health professionals and recommendations in osteoarthritis clinical practice guideline. For instance, in Australia, referral to a surgeon is five times more common than referral to allied health professionals that could help with conservative management. Furthermore, patients are ambivalent towards conservative management such as exercise, thinking it will be ineffective and may even cause harm to their already worn joints. The disconnect between practice guideline and care for patients with osteoarthritis limits optimal care. Therefore, this study aims to explore the attitudes towards and understanding of osteoarthritis held by Australian GPs, surgeons and patients with knee osteoarthritis. The overarching goal is to gather information needed to develop Australian-specific education and behaviour change programs for GPs, surgeons and osteoarthritis patients
- Funding
- University of Tasmania ($24,824)
- Scheme
- Grant- Research Enhancement Program
- Administered By
- University of Tasmania
- Research Team
- Balogun S; Aitken D; Winzenberg TM; Hansen EC; Newsham-West H; Laslett LL
- Year
- 2018
- Description
- Knee osteoarthritis is a highly heterogeneous condition characterised by a complex and multifactorial nature. The pain experience in knee osteoarthritis is similarly individualized and complex; some patients may present with pain that appears attributable to classic signs of joint damage, while others may present with pain due to psychological distress or central mechanisms. However, whether these variables (or interactions between variables) are representative of different pain phenotypes in knee osteoarthritis and whether patients with distinct pain phenotypes have different risk for long-term health outcomes are unknown. This project aims to identify the pain phenotypes in OA patients and compare the risk of long-term health outcomes between different pain phenotypes. This study will help clinicians better prioritize and target interventions to individual patients and will lead to better outcomes and fewer treatment complications currently associates with pharmaceutical and surgical interventions that are widely used to treat knee osteoarthritis.
- Funding
- University of Tasmania ($9,669)
- Scheme
- Grant- Research Enhancement Program
- Administered By
- University of Tasmania
- Research Team
- Pan F; Jones G; Winzenberg TM; Tian J; Aitken D
- Year
- 2018
- Description
- Aims: to compare efficacy of krill oil vs identical placebo on cartilage composition (T2 mapping values) in 260patients with clinical knee OA, significant knee pain and effusion on imaging, using a randomised, placebo-controlled double-blind design over six months in an NHMRC-funded clinical trial.
- Funding
- Menzies Institute for Medical Research ($30,000)
- Scheme
- Grant - Development Grant
- Administered By
- University of Tasmania
- Research Team
- Laslett LL; Eathakkattu Antony BS; Aitken D
- Year
- 2016
- Description
- This project will conduct a randomised open label pilot study on two potential treatments for back pain targeting Modic changes (zoledronic acid or denosumab).
- Funding
- Tasmanian Community Fund ($88,721)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Laslett LL; Aitken D; Jones G
- Year
- 2014
- Funding
- The Royal Society of Tasmania ($1,000)
- Scheme
- Doctoral (PhD) Award for 2013
- Administered By
- Menzies Research Institute Tasmania
- Research Team
- Aitken Dawn
- Year
- 2013
- Funding
- National Health & Medical Research Council ($299,564)
- Scheme
- Fellowship-Early Career
- Administered By
- University of Tasmania
- Research Team
- Aitken D
- Period
- 2013 - 2016
- Grant Reference
- 1052708
- Description
- Osteoarthritis (OA) is the most common form of arthritis and is increasing markedly due to an ageing population. Despite its large disease burden, there are currently no approved disease-modifying drugs available which modify structural progression of OA. The aim of this study is to compare zoledronic acid treatment to placebo on knee structural change and knee pain over two years. It is hypothesised that zoledronic acid will reduce cartilage loss, knee pain, and bone marrow lesion size.
- Funding
- National Health & Medical Research Council ($954,596)
- Scheme
- Grant-Project
- Administered By
- University of Tasmania
- Research Team
- Jones G; Cicuttini FM; March L; Hill C; Aitken D
- Period
- 2013 - 2015
- Grant Reference
- 1045415
- Funding
- University of Tasmania ($1,500)
- Scheme
- Grant-Conference Support Scheme
- Administered By
- University of Tasmania
- Research Team
- Aitken D
- Year
- 2012
- Funding
- Royal Australian College of General Practitioners/Osteoporosis Australia ($30,000)
- Scheme
- Grant-Bone Health
- Administered By
- University of Tasmania
- Research Team
- Winzenberg TM; Aitken D; Jones G
- Period
- 2012 - 2014
- Funding
- Arthritis Australia ($50,000)
- Scheme
- Fellowship-Research
- Administered By
- University of Tasmania
- Research Team
- Aitken D
- Year
- 2011
- Funding
- Osteoarthritis Research Society International ($6,126)
- Scheme
- Scholarship-Exchange
- Administered By
- University of Tasmania
- Research Team
- Aitken D
- Year
- 2010
Research Supervision
Current
4
Completed
10
Current
| Degree | Title | Commenced |
|---|---|---|
| PhD | The Relationship and Interactions between Sun Exposure, Skin Phenotype and Musculoskeletal Health in Older Adults | 2018 |
| PhD | Understanding the Management of Osteoarthritis in Tasmania and a Novel Approach to Change | 2018 |
| Masters | Objective Patient Centred Outcomes: Movement data in orthopaedic surgery | 2019 |
| PhD | Physical Activity and Osteoarthritis | 2021 |
Completed
| Degree | Title | Completed |
|---|---|---|
| PhD | Investigating the Evolution of Model-based Health Economic Evaluations and Changes in Health-related Quality of Life in Osteoarthritis Candidate: Ting Zhao | 2021 |
| PhD | Utilising Advanced Imaging to Understand Joint Pain and Function Limitations in Older Adults Candidate: Siti Maisarah Binti Mattap | 2021 |
| PhD | Clinical Trials of Bone-targeted Therapy for New Indications Candidate: Guoqi Cai | 2020 |
| PhD | Determinants and Management of the Progression of Osteoarthritis in Older Adults Candidate: Ishanka Praneeth Munugoda | 2020 |
| PhD | Knee Osteoarthritis, Its Comorbidity and the Role of Vitamin D Candidate: Shuang Zheng | 2019 |
| PhD | How and Why do Podiatrists Promote Physical Activity? Candidate: Paul Raymond Crisford | 2019 |
| PhD | Infrapatellar Fat Pad and Knee Osteoarthritis Candidate: Weiyu Han | 2019 |
| PhD | Long-Term Risk Factors for, and the Impact of Age-related Muscle Loss on the Musculoskeletal Health of Older Adults Candidate: Saliu Adejumobi Balogun | 2018 |
| PhD | Determinants of Structural Changes in the Knee Joint in a Middle-Aged Cohort with a Low Prevalence of Osteoarthritis Candidate: Hussain Ijaz Khan | 2017 |
| PhD | Assessment of Hip Structure and Musculature using MRI and DXA Images from Tasoac Cohort Candidate: Harbeer Kaur Ahedi | 2016 |