Profiles

Kazuaki Negishi

UTAS Home Dr Kaz Negishi

Kaz Negishi

Adjunct Professor
Menzies Institute for Medical Research

Medical Science 1 (MS1), Hobart CBD Campuses

+61 3 6226 7418 (phone)

Kazuaki.Negishi@utas.edu.au

Kazuaki (Kaz) Negishi is a Cardiologist, Professor of Medicine at the University of Sydney, and adjunct Professor at Menzies Institute for Medical Research, University of Tasmania. As a physician-scientist, he works in clinical research on Cardiovascular (CV) Medicine, via application of CV imaging modalities, such as echocardiography, myocardial strain imaging etc. His current interests are, the effect of air pollution on CV system, identification and risk stratification of subclinical CV dysfunction (cardiotoxicity of cancer chemo therapy, hypertension and diabetes), hemodynamics and heart failure. He also has been working on the effect of microgravity on the Cardiovascular system, collaborating with NASA.

Biography

Kaz has been working on cardiovascular research in Japan, USA, and Australia. Upon the completion of his clinical training in Internal medicine, he pursued cardiology career, including echocardiography and interventional cardiology fellowship and PhD in Japan.  Then, he moved to Cleveland Clinic, OH, USA to pursue his research interests and worked as a Post-doctoral Research Fellow for three years. He had worked at the Menzies Institute of Medical Research, University of Tasmania, Australia between 2013 and 2019. Early 2019, he moved to the University of Sydney.

Career summary

Qualifications

  • PhD, Gunma University, Japan. 2011
  • BMed (MBBS equivalent), Gunman University, Japan. 2000
  • EGFMG certificate, USA, 2012
  • FACC, American College of Cardiology, USA. 2014
  • FASC, European Society of Cardiology, Europ. 2014
  • FASE, American Society of Echocardiology, USA. 2015
  • FAHA, American Heart Association, USA, 2017
  • FCSANZ, Cardiac Society of Australia and New Zealand, 2017
  • FRACP, Royal Australasian College of Physicians, 2017

Languages (other than English)

Japanese

Memberships

Professional practice

  • American Heart Association (FAHA)
  • American College of Cardiology (FACC)
  • American Society of Echocardiography (FASE)
  • European Society of Cardiology (FESC)
  • Japanese Society of Internal Medicine
  • Japanese Circulation Society
  • Japanese College of Cardiology
  • Japanese Society of Echocardiography
  • Japanese Society of Ultrasonics in Medicine
  • Japanese Association of Cardiovascular Intervention and Therapeutics

Administrative expertise

Kaz started an echocardiography laboratory in Gunma University Hospital, where he served as the director to manage 2500-3000 transthoracic and 200-300 transesophageal echocardiograms per year and to train junior cardiology fellows and colleagues for five years. Kaz is leading the Echocardiography laboratory at Royal Hobart Hospital.

Teaching

Cardiovascular medicine, Cardiac Imaging, Echocardiography, Myocardial strain imaging, Cardiotoxicity, Air-pollution

Teaching expertise

Kaz's leadership skills are demonstrated through the training and supervision of field staff, research assistants and research fellows on a range of quantitative and qualitative projects. He provides informal mentoring to 4 early career postdoctoral fellows.

Teaching responsibility

Appointments:

  • Staff Specialist Cardiology at Royal Hobart Hospital (2018-)
  • Senior Lecturer at Menzies Institute of Medical Research, University of Tasmania (2013- )
  • Assistant Professor at Gunma University Graduate school of Medicine (2009-2010)

View more on Dr Kazuaki Negishi in WARP

Expertise

  • Cardiology
  • Cardiovascular medicine
  • Cardiac Imaging
  • Echocardiography
  • Myocardial strain imaging
  • Cardiotoxicity
  • Air-pollution

Research Themes

Kaz's research aligns to the University's research theme of Better Health. His research interests include understanding cardiovascular hemodynamics, identification of subclinical diseases (Stage B), elucidating the effect of air-pollution on CV system, further risk stratification, and the management of risk factors. Kaz's research into myocardial function has spread to working with the NASA in the USA to identify the behaviour of cardiovascular function in Space. Kaz is also researching the heart in haemodialysis patients, who mostly die from cardiovascular diseases. He keeps very good relationships with Japanese cardiologists and is supervising research projects and PhD students in echocardiography lab in Gunma University, Japan.

Collaboration

Kaz is currently involved in a series of ongoing international projects, which are primarily aimed at better understanding of cardiovascular functions, diseases and seeking the ways for prevention.

  • Gender differences in Cardiovascular medicine
  • Cardiovascular function in patients with haemodialysis
  • Effect of microgravity on the cardiovascular system (NASA, USA)
  • Hemodynamics in HFpEF and HFrEF
  • Echo-guided Intervention on cardiotoxicity (SUCCOUR study)

Awards

  • National Heart Foundation Future Leader Fellowship [2018-2021]
  • UTAS Research Conference Support Scheme (2014)
  • UTAS Research Enhancement Grant Scheme (2014)
  • UTAS Career development Scholarship (2014)
  • UTAS vTAHSP Demonstration Projects (2014)        
  • The Select Foundation: Fellowship-Senior Research (2012)
  • American Society of Echocardiography travel grant (2011)

Current projects

Kaz is currently working in collaboration with Dr Fay Johnston on The Latrobe ELF Study and with Professor Marwick on the SUCCOUR Study.

Fields of Research

  • Cardiology (incl. Cardiovascular Diseases) (110201)
  • Ecosystem Function (050102)
  • Environmental and Occupational Health and Safety (111705)
  • Cancer Cell Biology (111201)
  • Central Nervous System (110903)
  • Biodiscovery (100201)
  • Endocrinology (110306)
  • Dietetics and Nutrigenomics (111102)
  • Medical Biochemistry: Amino Acids and Metabolites (110101)
  • Epidemiology (111706)
  • Aboriginal and Torres Strait Islander Health (111701)

Research Objectives

  • Cardiovascular System and Diseases (920103)
  • Environmental Health (920405)
  • Occupational Health (920505)
  • Nervous System and Disorders (920111)
  • Blood Disorders (920101)
  • Diabetes (920104)
  • Atmospheric Processes and Dynamics (960202)
  • Child Health (920501)
  • Neurodegenerative Disorders Related to Ageing (920112)
  • Endocrine Organs and Diseases (excl. Diabetes) (920106)
  • Behaviour and Health (920401)

Publications

Kaz has >80 peer-reviewed publications predominantly in international journals, including JACC, JACC CV Img, Circulation CV Img, Heart, AJC, AHJ and JASE. Two of his papers on cardio-toxicity (Negishi JASE2013) (Negishi Eur H J CV Img 2014) have been cited in the US and EU expert consensus statement as crucial evidence bases for applying new echo technique (myocardial strain) and cut-off value for patients' management algorithms. His work on vendor difference in myocardial strain assessment helped identify this problem (Negishi UMB2013), and this led to the initiation of a Standardisation Task Force to solve this issue (Yang JASE2015). He is an Editorial Board member of several medical journals including, JACC: Cardiovascular Imaging and Journal of American Society of Echocardiography.

Total publications

115

Journal Article

(109 outputs)
YearCitationAltmetrics
2019Huynh QL, Negishi K, De Pasquale CG, Hare JL, Leung D, et al., 'Cognitive domains and postdischarge outcomes in hospitalized patients with heart failure', Circulation: Heart Failure, 12, (6) Article e006086. ISSN 1941-3289 (2019) [Refereed Article]

DOI: 10.1161/CIRCHEARTFAILURE.119.006086 [eCite] [Details]

Tweet

2019Huynh QL, Whitmore K, Negishi K, Marwick TH, 'Influence of risk on reduction of readmission and death by disease management programs in heart failure', Journal of Cardiac Failure, 25, (5) pp. 330-339. ISSN 1071-9164 (2019) [Refereed Article]

DOI: 10.1016/j.cardfail.2019.01.015 [eCite] [Details]

Citations: Scopus - 1Web of Science - 1

Co-authors: Whitmore K

Tweet

2019Pathan F, Negishi K, 'Back to the Future: Mitral annular plane systolic excursion on cardiac magnetic resonance', JACC: Cardiovascular Imaging pp. 1-3. ISSN 1936-878X (2019) [Letter or Note in Journal]

DOI: 10.1016/j.jcmg.2018.12.007 [eCite] [Details]

Citations: Web of Science - 1

Tweet

2019Przewlocka-Kosmala M, Marwick TH, Yang H, Wright L, Negishi K, et al., 'Association of reduced apical untwisting with incident HF in asymptomatic patients with HF risk factors', JACC: Cardiovascular Imaging pp. 1-8. ISSN 1936-878X (2019) [Refereed Article]

DOI: 10.1016/j.jcmg.2019.01.035 [eCite] [Details]

Citations: Web of Science - 1

Co-authors: Marwick TH; Kosmala W

Tweet

2019Sorimachi H, Kurosawa K, Yoshida K, Obokata M, Noguchi T, et al., 'Sex differences in left ventricular afterload and diastolic function are independent from the aortic size', PLoS One, 4, (4) Article e0214907. ISSN 1932-6203 (2019) [Refereed Article]

DOI: 10.1371/journal.pone.0214907 [eCite] [Details]

Tweet

2019Yoshida H, Seo Y, Ishizu T, Izumo M, Akashi YJ, et al., 'Prognostic value of energy loss coefficient for predicting asymptomatic aortic stenosis outcomes: Direct comparison with aortic valve area', Journal of the American Society of Echocardiography, 32, (3) pp. 351-358.e3. ISSN 0894-7317 (2019) [Refereed Article]

DOI: 10.1016/j.echo.2018.10.016 [eCite] [Details]

Tweet

2019Zhao B, Johnston FH, Dalton M, Negishi K, 'Feasibility and normal ranges of arterial intima-media thickness and stiffness in 2-year-old children: A pilot study', Pediatric Cardiology pp. 1-7. ISSN 0172-0643 (2019) [Refereed Article]

DOI: 10.1007/s00246-019-02088-1 [eCite] [Details]

Citations: Web of Science - 2

Co-authors: Johnston FH; Dalton M

Tweet

2019Kitano T, Nabeshima Y, Otsuji Y, Negishi K, Takeuchi M, 'Accuracy of left ventricular volumes and ejection fraction measurements by contemporary three-dimensional echocardiography with semi- and fully automated software: Systematic review and meta-analysis of 1,881 subjects', Journal of the American Society of Echocardiography pp. 1-11. ISSN 0894-7317 (2019) [Refereed Article]

DOI: 10.1016/j.echo.2019.04.417 [eCite] [Details]

Citations: Scopus - 1Web of Science - 15

Tweet

2018Yang H, Wright L, Negishi T, Negishi K, Liu J, et al., 'Research to Practice: assessment of left ventricular global longitudinal strain for surveillance of cancer chemotherapeutic-related cardiac dysfunction', JACC: Cardiovascular Imaging, 11, (8) pp. 1196-1201. ISSN 1936-878X (2018) [Refereed Article]

DOI: 10.1016/j.jcmg.2018.07.005 [eCite] [Details]

Citations: Scopus - 2Web of Science - 3

Co-authors: Yang H; Wright L; Negishi T; Marwick TH

Tweet

2018Huynh Q, Negishi K, De Pasquale C, Hare J, Leung D, et al., 'Effects of post-discharge management on rates of early re-admission and death after hospitalisation for heart failure', Medical Journal of Australia, 208, (11) pp. 485-491. ISSN 0025-729X (2018) [Refereed Article]

DOI: 10.5694/mja17.00809 [eCite] [Details]

Citations: Web of Science - 5

Co-authors: Huynh Q

Tweet

2018Huynh QL, Blizzard CL, Marwick TH, Negishi K, 'Association of ambient particulate matter with heart failure incidence and all-cause readmissions in Tasmania: an observational study', BMJ Open, 8, (5) Article e021798. ISSN 2044-6055 (2018) [Refereed Article]

DOI: 10.1136/bmjopen-2018-021798 [eCite] [Details]

Citations: Scopus - 1Web of Science - 1

Co-authors: Huynh QL; Blizzard CL; Marwick TH

Tweet

2018Iso T, Haruyama H, Sunaga H, Matsui H, Matsui M, et al., 'CD36 is indispensable for nutrient homeostasis and endurance exercise capacity during prolonged fasting', Physiological Reports, 6, (18) Article e13884. ISSN 2051-817X (2018) [Refereed Article]

DOI: 10.14814/phy2.13884 [eCite] [Details]

Citations: Scopus - 1

Tweet

2018Koshy AN, Sajeev JK, Negishi K, Wong MC, Pham CB, et al., 'Accuracy of blinded clinician interpretation of single-lead smartphone electrocardiograms and a proposed clinical workflow', American Heart Journal, 205 pp. 149-153. ISSN 0002-8703 (2018) [Refereed Article]

DOI: 10.1016/j.ahj.2018.08.001 [eCite] [Details]

Citations: Scopus - 2Web of Science - 3

Tweet

2018Nabeshima Y, Nagata Y, Negishi K, Seo Y, Ishizu T, et al., 'Direct comparison of severity grading assessed by two-dimensional, three-dimensional, and doppler echocardiography for predicting prognosis in asymptomatic aortic stenosis', Journal of the American Society of Echocardiography, 31, (10) pp. 1080-1090. ISSN 0894-7317 (2018) [Refereed Article]

DOI: 10.1016/j.echo.2018.05.006 [eCite] [Details]

Tweet

2018Negishi K, 'Echocardiographic feature of diabetic cardiomyopathy: where are we now?', Cardiovascular Diagnosis and Therapy, 8, (1) pp. 47-56. ISSN 2223-3652 (2018) [Refereed Article]

DOI: 10.21037/cdt.2018.01.03 [eCite] [Details]

Citations: Scopus - 5Web of Science - 3

Tweet

2018Negishi K, 'Incremental predictive value of left atrial parameters over clinical risk scores for subsequent atrial fibrillation: : Function beyond size', JACC: Cardiovascular Imaging, 12, (6) pp. 990-992. ISSN 1936-878X (2018) [Letter or Note in Journal]

DOI: 10.1016/j.jcmg.2018.03.026 [eCite] [Details]

Tweet

2018Negishi K, 'Incremental diagnostic value of left atrial strain over left atrial volume: An analogy of glucose level and glycosylated hemoglobin?', JACC: Cardiovascular Imaging, 11, (10) pp. 1416-1418. ISSN 1936-878X (2018) [Letter or Note in Journal]

DOI: 10.1016/j.jcmg.2017.10.011 [eCite] [Details]

Tweet

2018Negishi K, 'Echocardiography updates: from cardiac functional assessments to guiding procedures', Cardiovascular Diagnosis and Therapy, 8, (1) pp. 1-2. ISSN 2223-3652 (2018) [Letter or Note in Journal]

DOI: 10.21037/cdt.2017.11.01 [eCite] [Details]

Tweet

2018Negishi T, Negishi K, 'Echocardiographic evaluation of cardiac function after cancer chemotherapy', Journal of Echocardiography, 16, (1) pp. 20-27. ISSN 1349-0222 (2018) [Contribution to Refereed Journal]

DOI: 10.1007/s12574-017-0344-6 [eCite] [Details]

Citations: Scopus - 9Web of Science - 1

Co-authors: Negishi T

Tweet

2018Negishi T, Thavendiranathan P, Negishi K, Marwick TH, 'Rationale and design of the strain surveillance of chemotherapy for improving cardiovascular outcomes: the SUCCOUR Trial', JACC: Cardiovascular Imaging, 11, (8) pp. 1098-1105. ISSN 1936-878X (2018) [Refereed Article]

DOI: 10.1016/j.jcmg.2018.03.019 [eCite] [Details]

Citations: Scopus - 23Web of Science - 16

Co-authors: Negishi T; Marwick TH

Tweet

2018Obokata M, Kurosawa K, Ishida H, Ito K, Ogawa T, et al., 'Echocardiography-based pressure-volume loop assessment in the evaluation for the effects of indoxyl sulfate on cardiovascular function', Journal of Echocardiography, 17, (1) pp. 35-43. ISSN 1349-0222 (2018) [Refereed Article]

DOI: 10.1007/s12574-018-0385-5 [eCite] [Details]

Tweet

2018Saito M, Wright L, Negishi K, Dwyer N, Marwick TH, 'Mechanics and prognostic value of left and right ventricular dysfunction in patients with systemic sclerosis', European Heart Journal Cardiovascular Imaging, 19, (6) pp. 660-667. ISSN 2047-2404 (2018) [Refereed Article]

DOI: 10.1093/ehjci/jex147 [eCite] [Details]

Citations: Scopus - 4Web of Science - 4

Co-authors: Saito M; Wright L; Marwick TH

Tweet

2018Thavendiranathan P, Negishi T, Cote M-A, Penicka M, Massey R, et al., 'Single versus standard multiview assessment of global longitudinal strain for the diagnosis of cardiotoxicity during cancer therapy', JACC: Cardiovascular Imaging, 11, (8) pp. 1109-1118. ISSN 1936-878X (2018) [Refereed Article]

DOI: 10.1016/j.jcmg.2018.03.003 [eCite] [Details]

Citations: Scopus - 5Web of Science - 5

Co-authors: Negishi T; Marwick TH

Tweet

2018Vo HQ, Marwick TH, Negishi K, 'MRI-derived myocardial strain measures in normal subjects', JACC: Cardiovascular Imaging, 11, (2 part 1) pp. 196-205. ISSN 1936-878X (2018) [Refereed Article]

DOI: 10.1016/j.jcmg.2016.12.025 [eCite] [Details]

Citations: Scopus - 27Web of Science - 24

Co-authors: Marwick TH

Tweet

2018Harada T, Obokata M, Kurosawa K, Sorimachi H, Yoshida K, et al., 'Relationships of high cardiac output with ventricular morphology, myocardial energetics, and energy costs in hemodialysis patients with preserved ejection fraction', International Journal of Cardiovascular Imaging pp. 1-11. ISSN 1569-5794 (2018) [Refereed Article]

DOI: 10.1007/s10554-018-1472-4 [eCite] [Details]

Tweet

2018Wang Y, Yang H, Nolan M, Burgess J, Negishi K, et al., 'Association of depression with evolution of heart failure in patients with type 2 diabetes mellitus', Cardiovascular Diabetology, 17, (1) Article 19. ISSN 1475-2840 (2018) [Refereed Article]

DOI: 10.1186/s12933-018-0664-5 [eCite] [Details]

Citations: Scopus - 3Web of Science - 2

Co-authors: Yang H; Burgess J; Marwick TH

Tweet

2018Wang Y, Yang H, Nolan M, Pathan F, Negishi K, et al., 'Variations in subclinical left ventricular dysfunction, functional capacity, and clinical outcomes in different heart failure aetiologies', ESC Heart Failure, 5, (3) pp. 343-354. ISSN 2055-5822 (2018) [Refereed Article]

DOI: 10.1002/ehf2.12257 [eCite] [Details]

Citations: Scopus - 2Web of Science - 2

Co-authors: Yang H; Pathan F; Marwick TH

Tweet

2018Wassertheurer S, Hametner B, Mayer CC, Hafez A, Negishi K, et al., 'Aortic systolic pressure derived with different calibration methods: associations to brachial systolic pressure in the general population', Blood Pressure Monitoring, 23, (3) pp. 134-140. ISSN 1359-5237 (2018) [Refereed Article]

DOI: 10.1097/MBP.0000000000000319 [eCite] [Details]

Co-authors: Sharman JE

Tweet

2018Huynh Q, Negishi K, De Pasquale CG, Hare JL, Leung D, et al., 'Validation of predictive score of 30-day hospital readmission or death in patients with heart failure', American Journal of Cardiology, 121, (3) pp. 322-329. ISSN 0002-9149 (2018) [Refereed Article]

DOI: 10.1016/j.amjcard.2017.10.031 [eCite] [Details]

Citations: Scopus - 2Web of Science - 3

Co-authors: Huynh Q

Tweet

2018Zhao B, HQ Vo, Johnston FH, Negishi K, 'Air pollution and telomere length: a systematic review of 12,058 subjects', Cardiovascular Diagnosis and Therapy, 8, (4) pp. 480-492. ISSN 2223-3652 (2018) [Refereed Article]

DOI: 10.21037/cdt.2018.06.05 [eCite] [Details]

Citations: Scopus - 4Web of Science - 3

Co-authors: Johnston FH

Tweet

2018Wang Y, Yang H, Huynh Q, Nolan M, Negishi K, et al., 'Diagnosis of nonischemic stage B heart failure in type 2 diabetes mellitus: optimal parameters for prediction of heart failure', JACC: Cardiovascular Imaging, 11, (10) pp. 1390-1400. ISSN 1936-878X (2018) [Refereed Article]

DOI: 10.1016/j.jcmg.2018.03.015 [eCite] [Details]

Citations: Scopus - 5Web of Science - 5

Co-authors: Yang H; Huynh Q; Marwick TH

Tweet

2017Anwar S, Negishi K, Borowszki A, Gladding P, Popovic ZB, et al., 'Comparison of two-dimensional strain analysis using vendor-independent and vendor-specific software in adult and pediatric patients', JRSM Cardiovascular Disease, 6 pp. 1-11. ISSN 2048-0040 (2017) [Refereed Article]

DOI: 10.1177/2048004017712862 [eCite] [Details]

Citations: Web of Science - 7

Tweet

2017Nagata Y, Wu VC-C, Kado Y, Otani K, Lin F-C, et al., 'Prognostic value of right ventricular ejection fraction assessed by transthoracic 3D echocardiography', Circulation: Cardiovascular Imaging, 10, (2) Article e005384. ISSN 1942-0080 (2017) [Refereed Article]

DOI: 10.1161/CIRCIMAGING.116.005384 [eCite] [Details]

Citations: Scopus - 32Web of Science - 25

Tweet

2017Negishi K, 'Is Speckle-Tracking Echocardiography a Panacea? Experience Is Still Required', American Society of Echocardiography. Journal, 30, (2) pp. 168-169. ISSN 0894-7317 (2017) [Contribution to Refereed Journal]

DOI: 10.1016/j.echo.2016.12.003 [eCite] [Details]

Citations: Scopus - 1Web of Science - 1

Tweet

2017Negishi K, Borowski AG, Popovic ZB, Greenberg NL, Martin DS, et al., 'Effect of gravitational gradients on cardiac filling and performance', Journal of the American Society of Echocardiography, 30, (12) pp. 1180-1188. ISSN 0894-7317 (2017) [Refereed Article]

DOI: 10.1016/j.echo.2017.08.005 [eCite] [Details]

Citations: Scopus - 16Web of Science - 15

Tweet

2017Negishi T, Negishi K, Thavendiranathan P, Cho G-Y, Popescu BA, et al., 'Effect of Experience and Training on the Concordance and Precision of Strain Measurements', JACC: Cardiovascular Imaging, 10, (5) pp. 518-522. ISSN 1936-878X (2017) [Refereed Article]

DOI: 10.1016/j.jcmg.2016.06.012 [eCite] [Details]

Citations: Scopus - 28Web of Science - 21

Co-authors: Negishi T; Marwick TH

Tweet

2017Obokata M, Kurosawa K, Ishida H, Ito K, Ogawa T, et al., 'Incremental prognostic value of ventricular-arterial coupling over ejection fraction in patients with maintenance hemodialysis', Journal of the American Society of Echocardiography, 30, (5) pp. 444-453. ISSN 0894-7317 (2017) [Refereed Article]

DOI: 10.1016/j.echo.2016.12.014 [eCite] [Details]

Citations: Scopus - 7Web of Science - 8

Tweet

2017Obokata M, Negishi K, Sunaga H, Ishida H, Ito K, et al., 'Association between circulating ketone bodies and worse outcomes in hemodialysis patients', Journal of the American Heart Association, 6, (10) Article e006885. ISSN 2047-9980 (2017) [Refereed Article]

DOI: 10.1161/JAHA.117.006885 [eCite] [Details]

Citations: Scopus - 4Web of Science - 4

Tweet

2017Pathan F, D'Elia N, Nolan MT, Marwick TH, Negishi K, 'Normal ranges of left atrial strain by speckle-tracking echocardiography: A systematic review and meta-analysis', Journal of the American Society of Echocardiography, 30, (1) pp. 59-70. ISSN 0894-7317 (2017) [Refereed Article]

DOI: 10.1016/j.echo.2016.09.007 [eCite] [Details]

Citations: Scopus - 60Web of Science - 54

Co-authors: Pathan F; D'Elia N; Marwick TH

Tweet

2017Fonseca R, Otahal P, Galligan J, Neilson S, Huynh Q, et al., 'Association of survival time with transthoracic echocardiography in stable patients with heart failure: Is routine follow-up ever appropriate?', International Journal of Cardiology, 230 pp. 619-624. ISSN 0167-5273 (2017) [Refereed Article]

DOI: 10.1016/j.ijcard.2016.12.043 [eCite] [Details]

Co-authors: Fonseca R; Otahal P; Huynh Q; Saito M; Marwick TH

Tweet

2017Ramkumar S, Yang H, Wang Y, Nolan M, Negishi K, et al., 'Relation of functional status to risk of development of atrial fibrillation', American Journal of Cardiology, 119, (4) pp. 572-578. ISSN 0002-9149 (2017) [Refereed Article]

DOI: 10.1016/j.amjcard.2016.10.043 [eCite] [Details]

Citations: Scopus - 2Web of Science - 2

Co-authors: Yang H; Marwick TH

Tweet

2017Ramkumar S, Yang H, Wang Y, Nolan M, Negishi T, et al., 'Association of the active and passive components of left atrial deformation with left ventricular function', Journal of the American Society of Echocardiography, 30, (7) pp. 659-666. ISSN 0894-7317 (2017) [Refereed Article]

DOI: 10.1016/j.echo.2017.03.014 [eCite] [Details]

Citations: Scopus - 12Web of Science - 12

Co-authors: Yang H; Negishi T; Marwick TH

Tweet

2017Sato K, Grant ADM, Negishi K, Cremer PC, Negishi T, et al., 'Reliability of updated left ventricular diastolic function recommendations in predicting elevated left ventricular filling pressure and prognosis', American Heart Journal, 189 pp. 28-39. ISSN 0002-8703 (2017) [Refereed Article]

DOI: 10.1016/j.ahj.2017.03.022 [eCite] [Details]

Citations: Scopus - 15Web of Science - 16

Co-authors: Negishi T

Tweet

2017Sperry BW, Ibrahim A, Negishi K, Negishi T, Patel P, et al., 'Incremental prognostic value of global longitudinal strain and 18F-fludeoxyglucose positron emission tomography in patients with systemic sarcoidosis', American Journal of Cardiology, 119, (10) pp. 1663-1669. ISSN 0002-9149 (2017) [Refereed Article]

DOI: 10.1016/j.amjcard.2017.02.010 [eCite] [Details]

Citations: Scopus - 3Web of Science - 3

Co-authors: Negishi T; Marwick TH

Tweet

2017Wright L, Negishi K, Dwyer N, Wahi S, Marwick TH, 'Afterload dependence of right ventricular myocardial strain', Journal of the American Society of Echocardiography, 30, (7) pp. 676-684. ISSN 0894-7317 (2017) [Refereed Article]

DOI: 10.1016/j.echo.2017.03.002 [eCite] [Details]

Citations: Scopus - 5Web of Science - 4

Co-authors: Wright L; Marwick TH

Tweet

2017Yang H, Marwick TH, Wang Y, Nolan M, Negishi K, et al., 'Association between electrocardiographic and echocardiographic markers of stage B heart failure and cardiovascular outcome', ESC Heart Failure, 4, (4) pp. 417-431. ISSN 2055-5822 (2017) [Refereed Article]

DOI: 10.1002/ehf2.12151 [eCite] [Details]

Citations: Scopus - 3Web of Science - 3

Co-authors: Yang H; Marwick TH

Tweet

2017Yang H, Negishi K, Wang Y, Nolan M, Marwick TH, 'Imaging-guided cardioprotective treatment in a community elderly population of stage B heart failure', JACC: Cardiovascular Imaging, 10, (3) pp. 217-226. ISSN 1936-878X (2017) [Refereed Article]

DOI: 10.1016/j.jcmg.2016.11.015 [eCite] [Details]

Citations: Scopus - 10Web of Science - 9

Co-authors: Yang H; Marwick TH

Tweet

2017Pathan F, Sivaraj E, Negishi K, Rafiudeen R, Pathan S, et al., 'Use of atrial strain to predict atrial fibrillation after cerebral ischemia', JACC: Cardiovascular Imaging pp. 1-9. ISSN 1936-878X (2017) [Refereed Article]

DOI: 10.1016/j.jcmg.2017.07.027 [eCite] [Details]

Citations: Scopus - 12Web of Science - 42

Co-authors: Pathan F; Fonseca R; Marwick TH

Tweet

2016Huynh QL, Negishi K, Blizzard L, Saito M, De Pasquale CG, et al., 'Mild cognitive impairment predicts death and readmission within 30 days of discharge for heart failure', International Journal of Cardiology, 221 pp. 212-217. ISSN 0167-5273 (2016) [Refereed Article]

DOI: 10.1016/j.ijcard.2016.07.074 [eCite] [Details]

Citations: Scopus - 15Web of Science - 16

Co-authors: Huynh QL; Blizzard L; Saito M; Sanderson K; Venn AJ; Marwick TH

Tweet

2016Huynh QL, Negishi K, Blizzard L, Sanderson K, Venn AJ, et al., 'Predictive Score for 30-Day Readmission or Death in Heart Failure', JAMA Cardiology, 1, (3) pp. 362-364. ISSN 2380-6591 (2016) [Refereed Article]

DOI: 10.1001/jamacardio.2016.0220 [eCite] [Details]

Citations: Scopus - 11Web of Science - 13

Co-authors: Huynh QL; Blizzard L; Sanderson K; Venn AJ; Marwick TH

Tweet

2016Liou K, Negishi K, Ho S, Russell EA, Cranney G, et al., 'Detection of Obstructive Coronary Artery Disease Using Peak Systolic Global Longitudinal Strain Derived by Two-Dimensional Speckle-Tracking: A Systematic Review and Meta-Analysis', Journal of the American Society of Echocardiography, 29, (8) pp. 724-735.e4. ISSN 0894-7317 (2016) [Refereed Article]

DOI: 10.1016/j.echo.2016.03.002 [eCite] [Details]

Citations: Scopus - 10Web of Science - 11

Tweet

2016Negishi K, Negishi T, Zardkoohi O, Ching EA, Basu N, et al., 'Left atrial booster pump function is an independent predictor of subsequent life-threatening ventricular arrhythmias in non-ischaemic cardiomyopathy', European Heart Journal Cardiovascular Imaging, 17 pp. 1153-1160. ISSN 2047-2412 (2016) [Refereed Article]

DOI: 10.1093/ehjci/jev333 [eCite] [Details]

Citations: Scopus - 11Web of Science - 11

Co-authors: Negishi T; Marwick TH

Tweet

2016Negishi K, Yang H, Wang Y, Nolan MT, Negishi T, et al., 'Importance of calibration method in central blood pressure for cardiac structural abnormalities', American Journal of Hypertension, 29, (9) pp. 1070-1076. ISSN 0895-7061 (2016) [Refereed Article]

DOI: 10.1093/ajh/hpw039 [eCite] [Details]

Citations: Scopus - 5Web of Science - 13

Co-authors: Yang H; Negishi T; Pathan F; Marwick TH; Sharman JE

Tweet

2016Nolan MT, Russell DJ, Negishi K, Marwick TH, 'Meta-Analysis of Association Between Mediastinal Radiotherapy and Long-Term Heart Failure', The American Journal of Cardiology, 118, (11) pp. 1685-1691. ISSN 0002-9149 (2016) [Refereed Article]

DOI: 10.1016/j.amjcard.2016.08.050 [eCite] [Details]

Citations: Scopus - 5Web of Science - 5

Co-authors: Marwick TH

Tweet

2016Obokata M, Sunaga H, Ishida H, Ito K, Ogawa T, et al., 'Independent and incremental prognostic value of novel cardiac biomarkers in chronic hemodialysis patients', American Heart Journal, 179 pp. 29-41. ISSN 0002-8703 (2016) [Refereed Article]

DOI: 10.1016/j.ahj.2016.05.018 [eCite] [Details]

Citations: Scopus - 14Web of Science - 14

Tweet

2016Obokata M, Takeuchi M, Negishi K, Ohte N, Izumo M, et al., 'Relation Between Echocardiogram-Based Cardiac Parameters and Outcome in Heart Failure With Preserved and Reduced Ejection Fraction', American Journal of Cardiology, 118, (9) pp. 1356-1362. ISSN 0002-9149 (2016) [Refereed Article]

DOI: 10.1016/j.amjcard.2016.07.060 [eCite] [Details]

Citations: Scopus - 10Web of Science - 8

Tweet

2016Pathan F, Negishi K, 'Prediction of cardiovascular outcomes by imaging coronary atherosclerosis', Cardiovascular Diagnosis and Therapy, 6, (4) pp. 322-339. ISSN 2223-3652 (2016) [Refereed Article]

DOI: 10.21037/cdt.2015.12.08 [eCite] [Details]

Citations: Scopus - 2

Co-authors: Pathan F

Tweet

2016Saito M, Khan F, Stoklosa T, Iannaccone A, Negishi K, et al., 'Prognostic Implications of LV Strain Risk Score in Asymptomatic Patients With Hypertensive Heart Disease', JACC: Cardiovascular Imaging, 9, (8) pp. 911-921. ISSN 1936-878X (2016) [Refereed Article]

DOI: 10.1016/j.jcmg.2015.09.027 [eCite] [Details]

Citations: Scopus - 26Web of Science - 24

Co-authors: Saito M; Iannaccone A; Marwick TH

Tweet

2016Tsuchiya H, Nakano A, Hasegawa A, Nakazawa G, Negishi K, 'Rapid progression of nodular calcification documented by intra-coronary imaging devices and histology', European Heart Journal Cardiovascular Imaging, 17, (8) pp. 899. ISSN 2047-2404 (2016) [Letter or Note in Journal]

DOI: 10.1093/ehjci/jew088 [eCite] [Details]

Tweet

2016Wang Y, Yang H, Nolan M, Negishi K, Burgess J, et al., 'Association of waist circumference with impaired six-minute walk in type 2 diabetes mellitus is independent of cardiac function', Journal of Diabetes and Its Complications, 30, (3) pp. 542-544. ISSN 1056-8727 (2016) [Refereed Article]

DOI: 10.1016/j.jdiacomp.2015.12.014 [eCite] [Details]

Co-authors: Yang H; Burgess J; Marwick TH

Tweet

2016Yang H, Negishi K, Wang Y, Nolan M, Saito M, et al., 'Echocardiographic screening for non-ischaemic stage B heart failure in the community', European Journal of Heart Failure, 18, (11) pp. 1331-1339. ISSN 1388-9842 (2016) [Refereed Article]

DOI: 10.1002/ejhf.643 [eCite] [Details]

Citations: Scopus - 23Web of Science - 22

Co-authors: Yang H; Saito M; Marwick TH

Tweet

2016Yang H, Wang Y, Negishi K, Nolan M, Marwick TH, 'Pathophysiological effects of different risk factors for heart failure', Open Heart, 3, (1) Article e000339. ISSN 2053-3624 (2016) [Refereed Article]

DOI: 10.1136/openhrt-2015-000339 [eCite] [Details]

Citations: Web of Science - 6

Co-authors: Yang H; Marwick TH

Tweet

2016Yang H, Wang Y, Nolan M, Negishi K, Okin PM, et al., 'Community Screening for Nonischemic Cardiomyopathy in Asymptomatic Subjects ≥65 Years With Stage B Heart Failure', The American Journal of Cardiology, 117, (12) pp. 1959-1965. ISSN 0002-9149 (2016) [Refereed Article]

DOI: 10.1016/j.amjcard.2016.03.045 [eCite] [Details]

Citations: Scopus - 4Web of Science - 5

Co-authors: Yang H; Marwick TH

Tweet

2016Yoshida K, Obokata M, Kurosawa K, Sorimachi H, Kurabayashi M, et al., 'Effect of Sex Differences on the Association between Stroke Risk and Left Atrial Anatomy or Mechanics in Patients with Atrial Fibrillation', Circulation: Cardiovascular Imaging, 9, (10) Article e004999. ISSN 1942-0080 (2016) [Refereed Article]

DOI: 10.1161/CIRCIMAGING.116.004999 [eCite] [Details]

Citations: Scopus - 15Web of Science - 13

Tweet

2015Obokata M, Negishi K, Ohyama Y, Okada H, Imai K, et al., 'A risk score with additional four independent factors to predict the incidence and recovery from Metabolic Syndrome: development and validation in large Japanese cohorts', PLoS One, 10, (7) Article e0133884. ISSN 1932-6203 (2015) [Refereed Article]

DOI: 10.1371/journal.pone.0133884 [eCite] [Details]

Citations: Scopus - 4Web of Science - 4

Tweet

2015Fonseca R, Negishi K, Marwick TH, 'What is the evidence status of Appropriate Use Criteria (AUC)? Insight from a matching exercise with the guidelines for echocardiography', Internal Medicine Journal, 45, (8) pp. 864-869. ISSN 1444-0903 (2015) [Refereed Article]

DOI: 10.1111/imj.12829 [eCite] [Details]

Citations: Scopus - 7Web of Science - 6

Co-authors: Fonseca R; Marwick TH

Tweet

2015Huynh QL, Kalam K, Iannaccone A, Negishi K, Thomas L, et al., 'Functional and anatomic responses of the left atrium to change in estimated left ventricular filling pressure', Journal of the American Society of Echocardiography, 28, (12) pp. 1428-1433. ISSN 0894-7317 (2015) [Refereed Article]

DOI: 10.1016/j.echo.2015.07.028 [eCite] [Details]

Citations: Scopus - 13Web of Science - 12

Co-authors: Huynh QL; Kalam K; Iannaccone A; Marwick TH

Tweet

2015Huynh QL, Saito M, Blizzard CL, Eskandari M, Johnson B, et al., 'Roles of nonclinical and clinical data in prediction of 30-day rehospitalization or death among heart failure patients', Journal of Cardiac Failure, 21, (5) pp. 374-381. ISSN 1071-9164 (2015) [Refereed Article]

DOI: 10.1016/j.cardfail.2015.02.002 [eCite] [Details]

Citations: Scopus - 24Web of Science - 21

Co-authors: Huynh QL; Saito M; Blizzard CL; Marwick TH

Tweet

2015Kosmala W, Saito M, Kaye G, Negishi K, Linker N, et al., 'Incremental value of left atrial structural and functional characteristics for prediction of atrial fibrillation in patients receiving cardiac pacing', Circulation: Cardiovascular Imaging, 8, (4) Article e002942. ISSN 1941-9651 (2015) [Refereed Article]

DOI: 10.1161/CIRCIMAGING.114.002942 [eCite] [Details]

Citations: Scopus - 9Web of Science - 8

Co-authors: Kosmala W; Saito M; Marwick TH

Tweet

2015Nagata Y, Takeuchi M, Mizukoshi K, Wu VC-C, Lin F-C, et al., 'Intervendor variability of two-dimensional strain using vendor-specific and vendor-independent software', Journal of the American Society of Echocardiography, 28, (6) pp. 630-641. ISSN 0894-7317 (2015) [Refereed Article]

DOI: 10.1016/j.echo.2015.01.021 [eCite] [Details]

Citations: Scopus - 61Web of Science - 61

Tweet

2015Negishi K, Negishi T, Kurosawa K, Hristova K, Popescu BA, et al., 'Practical guidance in echocardiographic assessment of global longitudinal strain', JACC: Cardiovascular Imaging, 8, (4) pp. 489-492. ISSN 1936-878X (2015) [Contribution to Refereed Journal]

DOI: 10.1016/j.jcmg.2014.06.013 [eCite] [Details]

Citations: Scopus - 41Web of Science - 37

Co-authors: Negishi T; Marwick TH

Tweet

2015Negishi K, Popovic ZB, Negishi T, Motoki H, Alraies MC, et al., 'Pericardiectomy is associated with improvement in longitudinal displacement of left ventricular free wall due to increased counterclockwise septal-to-lateral rotational displacement', Journal of the American Society of Echocardiography, 28, (10) pp. 1204-1213. ISSN 0894-7317 (2015) [Refereed Article]

DOI: 10.1016/j.echo.2015.05.011 [eCite] [Details]

Citations: Scopus - 8Web of Science - 8

Co-authors: Negishi T

Tweet

2015Obokata M, Negishi K, Marwick TH, Kurosawa K, Ishida H, et al., 'Comparison of different interdialytic intervals among hemodialysis patients on their echocardiogram-based cardiovascular parameters', American Heart Journal, 169, (4) pp. 523-530.e2. ISSN 0002-8703 (2015) [Refereed Article]

DOI: 10.1016/j.ahj.2015.02.003 [eCite] [Details]

Citations: Scopus - 8Web of Science - 8

Co-authors: Marwick TH

Tweet

2015Grant ADM, Negishi K, Negishi T, Collier P, Kapadia SR, et al., 'Grading diastolic function by echocardiography: hemodynamic validation of existing guidelines', Cardiovascular Ultrasound, 13 Article 28. ISSN 1476-7120 (2015) [Refereed Article]

DOI: 10.1186/s12947-015-0023-6 [eCite] [Details]

Citations: Scopus - 13Web of Science - 13

Co-authors: Negishi T; Marwick TH

Tweet

2015Saito M, Iannaccone A, Kaye G, Negishi K, Kosmala W, et al., 'Effect of right ventricular pacing on right ventricular mechanics and tricuspid regurgitation in patients with high-grade atrioventricular block and sinus rhythm (from the Protection of Left Ventricular Function During Right Ventricular Pacing Study)', American Journal of Cardiology, 116, (12) pp. 1875-1882. ISSN 0002-9149 (2015) [Refereed Article]

DOI: 10.1016/j.amjcard.2015.09.041 [eCite] [Details]

Citations: Scopus - 9Web of Science - 10

Co-authors: Saito M; Iannaccone A; Kosmala W; Marwick TH

Tweet

2015Saito M, Kaye G, Negishi K, Linker N, Gammage M, et al., 'Dyssynchrony, contraction efficiency and regional function with apical and non-apical RV pacing', Heart, 101, (8) pp. 600-608. ISSN 1355-6037 (2015) [Refereed Article]

DOI: 10.1136/heartjnl-2014-306990 [eCite] [Details]

Citations: Scopus - 12Web of Science - 11

Co-authors: Saito M; Kosmala W; Marwick TH

Tweet

2015Saito M, Negishi K, Eskandari M, Huynh Q, Hawson J, et al., 'Association of left ventricular strain with 30-Day mortality and readmission in patients with heart failure', Journal of the American Society of Echocardiography, 28, (6) pp. 652-666. ISSN 0894-7317 (2015) [Refereed Article]

DOI: 10.1016/j.echo.2015.02.007 [eCite] [Details]

Citations: Scopus - 22Web of Science - 19

Co-authors: Saito M; Huynh Q; Marwick TH

Tweet

2015Saito M, Negishi K, Marwick TH, 'Meta-analysis of risks for short-term readmission in patients with heart failure', American Journal of Cardiology, 117, (4) pp. 626-632. ISSN 0002-9149 (2015) [Refereed Article]

DOI: 10.1016/j.amjcard.2015.11.048 [eCite] [Details]

Citations: Scopus - 23Web of Science - 20

Co-authors: Saito M; Marwick TH

Tweet

2015Wang Y, Negishi T, Negishi K, Marwick TH, 'Prediction of heart failure in patients with type 2 diabetes mellitus - A systematic review and meta-analysis', Diabetes Research and Clinical Practice, 108, (1) pp. 55-66. ISSN 0168-8227 (2015) [Refereed Article]

DOI: 10.1016/j.diabres.2015.01.011 [eCite] [Details]

Citations: Scopus - 12Web of Science - 8

Co-authors: Negishi T; Marwick TH

Tweet

2015Yang H, Marwick TH, Fukuda N, Oe H, Saito M, et al., 'Improvement in strain concordance between two major vendors after the Strain Standardization Initiative', Journal of the American Society of Echocardiography, 28, (6) pp. 642-648.e7. ISSN 0894-7317 (2015) [Refereed Article]

DOI: 10.1016/j.echo.2014.12.009 [eCite] [Details]

Citations: Scopus - 64Web of Science - 61

Co-authors: Yang H; Marwick TH; Saito M

Tweet

2015Yang H, Negishi K, Otahal P, Marwick TH, 'Clinical prediction of incident heart failure risk: a systematic review and meta-analysis', Open Heart, 2 Article e000222. ISSN 2053-3624 (2015) [Refereed Article]

DOI: 10.1136/openhrt-2014-000222 [eCite] [Details]

Citations: Scopus - 31Web of Science - 31

Co-authors: Yang H; Otahal P; Marwick TH

Tweet

2015Fonseca R, Negishi K, Otahal P, Marwick TH, 'Temporal changes in appropriateness of cardiac imaging', Journal of the American College of Cardiology, 65, (8) pp. 763-773. ISSN 0735-1097 (2015) [Refereed Article]

DOI: 10.1016/j.jacc.2014.11.057 [eCite] [Details]

Citations: Scopus - 51Web of Science - 50

Co-authors: Fonseca R; Otahal P; Marwick TH

Tweet

2014Alraies MC, Kusunose K, Negishi K, Yarmohammadi H, Motoki H, et al., 'Relation between echocardiographically estimated and invasively measured filling pressures in constrictive pericarditis', The American Journal of Cardiology, 113, (11) pp. 1911-1916. ISSN 0002-9149 (2014) [Refereed Article]

DOI: 10.1016/j.amjcard.2014.03.022 [eCite] [Details]

Citations: Scopus - 10Web of Science - 11

Tweet

2014Fukuda N, Itatani K, Kimura K, Ebihara A, Negishi K, et al., 'Prolonged vortex formation during the ejection period in the left ventricle with low ejection fraction: a study by vector flow mapping', Journal of Medical Ultrasonics, 41, (3) pp. 301-310. ISSN 1346-4523 (2014) [Refereed Article]

DOI: 10.1007/s10396-014-0530-3 [eCite] [Details]

Citations: Scopus - 9Web of Science - 9

Tweet

2014Motoki H, Negishi K, Kusunose K, Popovic ZB, Bhargava M, et al., 'Global left atrial strain in the prediction of sinus rhythm maintenance after catheter ablation for atrial fibrillation', Journal of the American Society of Echocardiography, 27, (11) pp. 1184-1192. ISSN 0894-7317 (2014) [Refereed Article]

DOI: 10.1016/j.echo.2014.08.017 [eCite] [Details]

Citations: Scopus - 41Web of Science - 38

Co-authors: Marwick TH

Tweet

2014Negishi K, Negishi T, Haluska BA, Hare JL, Plana JC, et al., 'Use of speckle strain to assess left ventricular responses to cardiotoxic chemotherapy and cardioprotection', European Heart Journal Cardiovascular Imaging, 15, (3) pp. 324-331. ISSN 2047-2404 (2014) [Refereed Article]

DOI: 10.1093/ehjci/jet159 [eCite] [Details]

Citations: Scopus - 99Web of Science - 94

Co-authors: Marwick TH

Tweet

2014Obokata M, Negishi K, Kurosawa K, Tateno R, Tange S, et al., 'Left atrial strain provides incremental value for embolism risk stratification over CHA2DS2-VASc score and indicates prognostic impact in patients with atrial fibrillation', Journal of the American Society of Echocardiography, 27, (7) pp. 709-716.e4. ISSN 0894-7317 (2014) [Refereed Article]

DOI: 10.1016/j.echo.2014.03.010 [eCite] [Details]

Citations: Scopus - 49Web of Science - 47

Tweet

2014Park JH, Negishi K, Kwon DH, Popovic ZB, Grimm RA, et al., 'Validation of global longitudinal strain and strain rate as reliable markers of right ventricular dysfunction: comparison with cardiac magnetic resonance and outcome', Journal of Cardiovascular Ultrasound, 22, (3) pp. 113-120. ISSN 1975-4612 (2014) [Refereed Article]

DOI: 10.4250/jcu.2014.22.3.113 [eCite] [Details]

Citations: Scopus - 36

Co-authors: Marwick TH

Tweet

2013Aldweib N, Negishi K, Hachamovitch R, Jaber WA, Seicean S, et al., 'Impact of repeat myocardial revascularization on outcome in patients with silent ischemia after previous revascularization', Journal of the American College of Cardiology, 61, (15) pp. 1616-1623. ISSN 0735-1097 (2013) [Refereed Article]

DOI: 10.1016/j.jacc.2013.01.043 [eCite] [Details]

Citations: Scopus - 20Web of Science - 23

Co-authors: Marwick TH

Tweet

2013Kurosawa K, Negishi K, Tateno R, Koitabashi N, Koike N, et al., 'Multiple papillary fibroelastomas of the aortic valve detected by real time three-dimensional transesophageal echocardiographic images', Journal of Cardiology Cases, 8, (1) pp. e9-e12. ISSN 1878-5409 (2013) [Refereed Article]

DOI: 10.1016/j.jccase.2013.02.014 [eCite] [Details]

Tweet

2013Negishi K, Lucas S, Negishi T, Hamilton J, Marwick TH, 'What is the primary source of discordance in strain measurement between vendors: imaging or analysis?', Ultrasound in Medicine and Biology, 39, (4) pp. 714-720. ISSN 0301-5629 (2013) [Refereed Article]

DOI: 10.1016/j.ultrasmedbio.2012.11.021 [eCite] [Details]

Citations: Scopus - 51Web of Science - 52

Co-authors: Marwick TH

Tweet

2013Negishi K, Negishi T, Hare JL, Haluska BA, Plana JC, et al., 'Independent and incremental value of deformation indices for prediction of trastuzumab-induced cardiotoxicity', Journal of the American Society of Echocardiography, 26, (5) pp. 493-498. ISSN 0894-7317 (2013) [Refereed Article]

DOI: 10.1016/j.echo.2013.02.008 [eCite] [Details]

Citations: Scopus - 200Web of Science - 173

Co-authors: Marwick TH

Tweet

2013Negishi K, Seicean S, Negishi T, Yingchoncharoen T, Aljaroudi W, et al., 'Relation of heart-rate recovery to new onset heart failure and atrial fibrillation in patients with diabetes mellitus and preserved ejection fraction', The American Journal of Cardiology, 111, (5) pp. 748-753. ISSN 0002-9149 (2013) [Refereed Article]

DOI: 10.1016/j.amjcard.2012.11.028 [eCite] [Details]

Citations: Scopus - 13Web of Science - 16

Co-authors: Marwick TH

Tweet

2013Obokata M, Negishi K, Kurosawa K, Arima H, Tateno R, et al., 'Incremental diagnostic value of la strain with leg lifts in heart failure with preserved ejection fraction', JACC: Cardiovascular Imaging, 6, (7) pp. 749-758. ISSN 1936-878X (2013) [Refereed Article]

DOI: 10.1016/j.jcmg.2013.04.006 [eCite] [Details]

Citations: Scopus - 42Web of Science - 39

Tweet

2013Park JH, Negishi K, Grimm RA, Popovic Z, Stanton T, et al., 'Echocardiographic predictors of reverse remodeling after cardiac resynchronization therapy and subsequent events', Circulation: Cardiovascular Imaging, 6, (6) pp. 864-872. ISSN 1941-9651 (2013) [Refereed Article]

DOI: 10.1161/CIRCIMAGING.112.000026 [eCite] [Details]

Citations: Scopus - 22Web of Science - 23

Co-authors: Marwick TH

Tweet

2013Wu VC-C, Takeuchi M, Kuwaki H, Iwataki M, Nagata Y, et al., 'Prognostic value of LA volumes assessed by transthoracic 3D echocardiography: Comparison with 2D echocardiography', JACC: Cardiovascular Imaging, 6, (10) pp. 1025-1035. ISSN 1936-878X (2013) [Refereed Article]

DOI: 10.1016/j.jcmg.2013.08.002 [eCite] [Details]

Citations: Scopus - 40Web of Science - 38

Tweet

2013Aldweib N, Negishi K, Seicean S, Jaber WA, Hachamovitch R, et al., 'Appropriate test selection for single-photon emission computed tomography imaging: Association with clinical risk, posttest management, and outcomes', American Heart Journal, 166, (3) pp. 581-588. ISSN 0002-8703 (2013) [Refereed Article]

DOI: 10.1016/j.ahj.2013.06.003 [eCite] [Details]

Citations: Scopus - 9Web of Science - 9

Co-authors: Marwick TH

Tweet

2012Fukuda S, Watanabe H, Daimon M, Abe Y, Hirashiki A, et al., 'Normal values of real-time 3-dimensional echocardiographic parameters in a healthy Japanese population: The JAMP-3D study', Circulation Journal, 76, (5) pp. 1177-1181. ISSN 1346-9843 (2012) [Refereed Article]

DOI: 10.1253/circj.CJ-11-1256 [eCite] [Details]

Citations: Scopus - 43Web of Science - 45

Tweet

2012Negishi K, Negishi T, Agler DA, Plana JC, Marwick TH, 'Role of temporal resolution in selection of the appropriate strain technique for evaluation of subclinical myocardial dysfunction', Echocardiography: A Journal of Cardiovascular Ultrasound and Allied Techniques, 29, (3) pp. 334-339. ISSN 0742-2822 (2012) [Refereed Article]

DOI: 10.1111/j.1540-8175.2011.01586.x [eCite] [Details]

Citations: Scopus - 30Web of Science - 25

Co-authors: Marwick TH

Tweet

2011Daimon M, Watanabe H, Abe Y, Hirata K, Hozumi T, et al., 'Gender differences in age-related changes in left and right ventricular geometries and functions: Echocardiography of a healthy subject group', Circulation Journal, 75, (12) pp. 2840-2846. ISSN 1346-9843 (2011) [Refereed Article]

DOI: 10.1253/circj.CJ-11-0364 [eCite] [Details]

Citations: Scopus - 30Web of Science - 30

Tweet

2011Takagi Y, Hozumi T, Takemoto Y, Negishi K, Hong Z, et al., 'Detection of prolonged regional myocardial systolic dysfunction after exercise-induced myocardial ischemia by strain echocardiography with high frame rate tissue Doppler echocardiography', Journal of Echocardiography, 9, (3) pp. 90-96. ISSN 1349-0222 (2011) [Refereed Article]

DOI: 10.1007/s12574-011-0082-0 [eCite] [Details]

Citations: Scopus - 1

Tweet

2011Takahashi R, Negishi K, Watanabe A, Arai M, Naganuma F, et al., 'Serum syndecan-4 is a novel biomarker for patients with chronic heart failure', Journal of Cardiology, 57, (3) pp. 325-332. ISSN 0914-5087 (2011) [Refereed Article]

DOI: 10.1016/j.jjcc.2011.01.012 [eCite] [Details]

Citations: Scopus - 28Web of Science - 27

Tweet

2010Negishi K, Kobayashi M, Ochiai I, Yamazaki Y, Hasegawa H, et al., 'Association between fibroblast growth factor 23 and left ventricular hypertrophy in maintenance hemodialysis patients. Comparison with B-type natriuretic peptide and cardiac troponin T', Circulation Journal, 74, (12) pp. 2734-2740. ISSN 1346-9843 (2010) [Refereed Article]

DOI: 10.1253/circj.CJ-10-0355 [eCite] [Details]

Citations: Scopus - 34Web of Science - 33

Tweet

2010Negishi K, Tsuchiya H, Nakajima M, Goto K, Kurosawa K, et al., 'The seabed-like appearance of atherosclerotic plaques: three-dimensional transesophageal echocardiographic images of the aortic arch causing cholesterol crystal emboli', Journal of the American Society of Echocardiography, 23, (11) pp. 1222.e1-4. ISSN 0894-7317 (2010) [Refereed Article]

DOI: 10.1016/j.echo.2010.04.003 [eCite] [Details]

Citations: Scopus - 6Web of Science - 4

Tweet

2009Negishi K, Ono Y, Kurosawa K, Takamatsu H, Nakano A, et al., 'Infective endocarditis complicated by mycotic aneurysm of a coronary artery with a perforated mitral valvular aneurysm', Journal of the American Society of Echocardiography, 22, (5) pp. 542.e1-4. ISSN 0894-7317 (2009) [Refereed Article]

DOI: 10.1016/j.echo.2009.01.020 [eCite] [Details]

Citations: Scopus - 7Web of Science - 5

Tweet

2008Daimon M, Watanabe H, Abe Y, Hirata K, Hozumi T, et al., 'Normal values of echocardiographic parameters in relation to age in a healthy Japanese population - The JAMP study', Circulation Journal, 72, (11) pp. 1859-1866. ISSN 1346-9843 (2008) [Refereed Article]

DOI: 10.1253/circj.CJ-08-0171 [eCite] [Details]

Citations: Scopus - 95Web of Science - 87

Tweet

2008Oe H, Hozumi T, Murata E, Matsuura H, Negishi K, et al., 'Arachidonic acid and docosahexaenoic acid supplementation increases coronary flow velocity reserve in Japanese elderly individuals', Heart, 94, (3) pp. 316-321. ISSN 1355-6037 (2008) [Refereed Article]

DOI: 10.1136/hrt.2006.113159 [eCite] [Details]

Citations: Scopus - 22Web of Science - 19

Tweet

2006Zhu H, Hozumi T, Takemoto Y, Takagi Y, Negishi K, et al., 'Estimation of myocardial ischemia by diastolic strain analysis in exercise stress echocardiography: comparison with exercise thallium-201 single photon emission computed tomography', Journal of Cardiology, 47, (4) pp. 165-172. ISSN 0914-5087 (2006) [Refereed Article]

[eCite] [Details]

2005Oe H, Hozumi T, Arai K, Matsumura Y, Negishi K, et al., 'Comparison of accurate measurement of left ventricular mass in patients with hypertrophied hearts by real-time three-dimensional echocardiography versus magnetic resonance imaging', The American Journal of Cardiology, 95, (10) pp. 1263-1267. ISSN 0002-9149 (2005) [Refereed Article]

DOI: 10.1016/j.amjcard.2005.01.065 [eCite] [Details]

Citations: Scopus - 50Web of Science - 39

Tweet

Chapter in Book

(1 outputs)
YearCitationAltmetrics
2016Negishi K, Marwick TH, 'Left Ventricular Systolic Function', ASE's Comprehensive Echocardiography, 2nd Edition, Elsevier, R Lang, SA Goldstein, I Kronzon, BK Khandheria & V M-A (ed), Canada, pp. 113-115. ISBN 978-0-323-26011-4 (2016) [Other Book Chapter]

[eCite] [Details]

Co-authors: Marwick TH

Conference Publication

(5 outputs)
YearCitationAltmetrics
2017Zhao B, Salimi F, Johnston F, Oshima K, Kurabayashi M, et al., 'Abstract 16338: A Case-Crossover Study of Short Term Effects of Air Pollutants on Stroke in Gunma, Japan', Circulation, pp. A16338, Vol 134, Suppl 1. ISSN 0009-7322 (2017) [Conference Extract]

[eCite] [Details]

Co-authors: Salimi F; Johnston F

2017Zhao B, Salimi F, Johnston F, Oshima K, Kurabayashi M, et al., 'Abstract 16275: Out-of-Hospital Cardiac Arrest and Short-Term Exposure to Air Pollutants: A Case-Crossover Study', Circulation, pp. A16275, Vol 134, Suppl1. ISSN 0009-7322 (2017) [Conference Extract]

[eCite] [Details]

Co-authors: Salimi F; Johnston F

2017Zhao B, Salimi F, Johnston J, Oshima K, Kurabayashi M, et al., 'Abstract 16370: Short Term Effects of Photochemical Oxidant on Heart Failure: A Case-Crossover Study', Circulation, Circulation, pp. A16370-A16370, Vol 134, Suppl 1. ISSN 0009-7322 (2017) [Conference Extract]

[eCite] [Details]

Co-authors: Salimi F; Johnston J

2015Huynh L, Johnston F, Blizzard CL, Marwick TH, Negishi K, 'The effects of temperature and air pollution on heart failure incidence and readmissions: is beta-blocker protective?', European Heart Journal, pp. 1006, Vol 36. ISSN 0195-668X (2015) [Conference Extract]

[eCite] [Details]

Co-authors: Huynh L; Johnston F; Blizzard CL; Marwick TH

2015Huynh L, Johnston F, Blizzard CL, Marwick TH, Negishi K, 'Threshold of ambient particulate matter level for increasing heart failure incidence may be lower than national standard', European Heart Journal, pp. 331, Vol 36. ISSN 0195-668X (2015) [Conference Extract]

[eCite] [Details]

Co-authors: Huynh L; Johnston F; Blizzard CL; Marwick TH

Grants & Funding

Funding Summary

Number of grants

8

Total funding

$1,890,554

Projects

Effectiveness of imaging pathways for CVD epidemics of the elderly (2018 - 2020)$703,875
Description
Cardiovascular imaging, especially echocardiography, is a cornerstone of modern cardiology; guidelines stipulate the use of echocardiography to inform therapeutic intervention in heart failure and valvular heart disease. However, there is also a risk of overuse, and in contrast to North America, where the growth of imaging has been controlled over the last decade, use in Australia continues to grow at ~10% per year. The dependence on imaging is greater in the cardiovascular disease (CVD) epidemics of the elderly (atrial fibrillation [AF], aortic stenosis [AS] and heart failure [HF]) than in other diagnoses. Not only are large numbers of tests being done currently, but the growth of these conditions will magnify the problem over the coming years. Failure to manage the hospitalisation, device and procedural costs for treatment of these new CV epidemics can be linked to shortcomings in the practice of CV imaging. The need for ongoing surveillance that is heavily dependent on cardiac imaging will introduce new complexities around imaging quality. Despite the expenditure of ~$1 billion/year on CV imaging in Australia, there is little evidence of value. The Partnership will link researchers with providers and imaging industry to improve all steps of the imaging "value chain" - ranging from the selection of suitable patients to the quality of interpretation. These studies will improve appropriate selection for testing, quality control and integration of decision-making with imaging.
Funding
National Health & Medical Research Council ($703,875)
Scheme
Grant-Partnership Project
Administered By
Baker Heart and Diabetes Institute
Research Team
Marwick TH; Chew D; Kaye D; Negishi K; Stocks N; Blizzard CL; Doust J
Period
2018 - 2020
Grant Reference
1149692
Clinical application of cardiovascular imaging for detection of subclinical cardiovascular dysfunction and establishing treatment (2018 - 2021)$376,000
Description
This project aims to identify the early signs of heart diseases and to better understand precise mechanisms using new imaging techniques. Early detection will enable suitable management of these diseases by providing treatment to protect the heart. The avoidance or delay of CV disease will achieve better health outcomes in Australia. For this purpose, four clinical studies on CV medicine will be performed: Study 1 is an international multicentre project to examine if a new imaging technique (myocardial strain) for finding early disease provides a better guide for protecting the heart from cardiotoxic chemotherapy agents. In Study 2, a series of cross-sectional studies will be performed using data from an ongoing trial with the aim of determining the relationship between central blood pressure (BP) and heart damage. Study 3 is a 10-year observational study of the foetus (mothers) and infants who were exposed to smoke from the Hazelwood coal mine fire in Victoria in 2014. Early changes in the blood vessels from smoke exposure will be determined. Study 4 will explore if individual measure of air pollution would be a better marker of heart and vessel damages compared to traditional city-level measure. This program will make a significant contribution to Australias medical research capacity and knowledge, with potential to develop evidence based CVD health policies, and with results being translated into practice.
Funding
National Heart Foundation ($376,000)
Scheme
Fellowship-Future Leader
Administered By
University of Tasmania
Research Team
Negishi K
Period
2018 - 2021
Effect of ambient air quality on cardiovascular disease and telomere length (2017)$25,000
Description
Although air-pollution is widely known to cause lung damage, it's effect on heart health is greater than its effects on lung diseases of cancers. In this proposal, we will investigate the effect of individual level exposure to outdoor air pollution on heart disease as well as a marker of ageing.
Funding
Avant Insurance Ltd ($25,000)
Scheme
Scholarship - Doctor in Training
Administered By
University of Tasmania
Research Team
Negishi K
Year
2017
Use of Advanced Cardiac Imaging in Radiation-Related Cardiotoxicity. (2015 - 2017)$90,000
Description
Successful advances in oncology over past decades have led to 5-year cancer survival rate improving from 50% in 1975-77 to 68% in 1999-2005. This success has led to a large pool of cancer survivors who are at substantial risk of cardiovascular morbiity and mortality. The specific complication of chemotherapy-induced cardiotoxicity (CTX), including radiotherapy cardiotoxicity, may occur in up to 20% patients within 5 years, and has a 50% mortality rate by 2 years. Cardioprotective (CP) medications have been demonstrated to reduce the risk of CTX, but uniform use would impose a financial burden on the health care system and expose many patients to unnecessary side-effects. One means of targeting CP to patients most likely to benefit is the use of novel echocardiographic techniques to detect preclinical cardiac damage. 2D-strain echocardiography measures changes in regional myocardial deformation, and identifies an earlier stage of cardiac dysfunction than the current standard of using left-ventricular-ejection-fraction (LVEF)-guided therapy. By identifying patients at an earlier stage,it is likely possible to target patients during a window when they are more likely to be responsive to CP, and avoids uneccessarily exposing patients who would never develop CTX to side-effects and costs of CP.
Funding
National Heart Foundation ($90,000)
Scheme
Scholarship-Health Professional
Administered By
University of Tasmania
Research Team
Marwick TH; Nolan M; Negishi K
Period
2015 - 2017
Tasmanian Study of Echocardiographic Detection of Left Ventricular Dysfunction (2014)$53,679
Description
HF is increasing in Australia but treatment in the early stages is able to prevent or delay its progression. The problem is how to recognise the early phase. This project will: implement a screening tool for heart failure; deliver an effective heart failure screening outreach service; and implement an effective communication process to Primary Care and referral to Cardiology. A database will be established to support follow up and personalised care of at risk subjects. This study expects to prevent 24 people developing heart failure.
Funding
University of Tasmania ($53,679)
Scheme
vTAHSP Demonstration Projects
Administered By
University of Tasmania
Research Team
Marwick TH; Herman BA; Seidel BM; Lees Michael; Sharman JE; Negishi K; Yang Hilda
Year
2014
Early detection of cardiovascular risk using comprehensive evaluation of endothelial function in occupations exposed to inhaled particulates (2014)$14,500
Funding
University of Tasmania ($14,500)
Scheme
Grant-Research Enhancement (REGS)
Administered By
University of Tasmania
Research Team
Negishi K
Year
2014
American College of Cardiology 63rd Annual Meeting, Washington DC, USA (2014)$2,500
Funding
University of Tasmania ($2,500)
Scheme
Grant-Conference Support Scheme
Administered By
University of Tasmania
Research Team
Negishi K
Year
2014
Select Foundation Fellowship - Dr Kazuaki Negishi (2013 - 2017)$625,000
Description
Relates to Fellowship No. 2.
Funding
The Select Foundation ($625,000)
Scheme
Fellowship-Senior Research
Administered By
University of Tasmania
Research Team
Negishi K
Period
2013 - 2017

Research Supervision

Kaz is currently a primary supervisor and co-supervisor of a number of PhD and Masters candidates. He has successfully supervised 4 students to completion: 2 PhD and 2 Honours (1st class) as primary supervisor and 4 PhD and 1 Honours (1st class) as co-supervisor. Thinking of undertaking a PhD? Feel free to discuss ideas with Kaz. There are lists of potential PhD topics in cardiovascular medicine.

Current

3

Completed

4

Current

DegreeTitleCommenced
PhDImaging for Cardiac Dysfunction Secondary to Cancer Treatment2014
PhDApplication of Cardiac Imaging in Hypertensive Patients2015
PhDAir Pollution and Cardiovascular Diseases2015

Completed

DegreeTitleCompleted
PhDThe Role of Advanced Cardiovascular Imaging in the Management of the New Cardiovascular Epidemics of Old Age
Candidate: Faraz Khalid Pathan
2019
PhDDetection of Stage B Heart Failure in Type 2 Diabetes Mellitus
Candidate: Ying Wang
2018
PhDAppropriate Use of Cardiac Imaging in Australia
Candidate: Ricardo Andres Fonseca Diaz
2017
PhDCommunity Detection of Non-Ischemic Stage B Heart Failure
Candidate: Hong Yang
2017