Profiles

Stephen Rattigan

UTAS Home Prof Stephen Rattigan

Stephen Rattigan

Professor
Menzies Institute for Medical Research

Medical Science , Hobart CBD Campuses

+61 3 6226 2671 (phone)

+61 3 6226 7704 (fax)

S.Rattigan@utas.edu.au

Professor Steve Rattigan is a senior member of the Menzies Institute for Medical Research. He leads a group of researchers studying the mechanisms underlying the development of insulin resistance and diabetes. His discoveries have highlighted the important role that insulin has in controlling microvascular blood flow in skeletal muscle and regulating glucose uptake and insulin sensitivity.

Biography

Professor Rattigan did his PhD studies at the University of Western Australia, and has worked previously at CSIRO, Division of Human Nutrition, Adelaide (1982-5), University of Tasmania (1985-1994), University of Virginia, USA (1994-7) and acted as the Deputy Director of The Menzies Institute for Medical Research at the University of Tasmania (2010-2014).

Memberships

Professional practice

  • Secretary, Australian & New Zealand Microcirculation Society
  • Australian Physiology Society (Chair Local Organising Committee for Annual Meeting, Hobart 2015)
  • Australian Diabetes Society
  • American Diabetes Association
  • American Physiology Society
  • The Microcirculatory Society
  • American Heart Association
  • American Association for Advancement of Science

Administrative expertise

  • Deputy Director Menzies Institute for Medical Research (2010-2014)
  • Chair Laboratory Management Committee (Medical Sciences Building) 2009-2014
  • Member Project Control Group for Medical Sciences Building Stage 2 Development

Teaching

Teaching expertise

  • Supervision of Honours and PhD students in Biochemistry and Medical Sciences

Research Appointments

  • NHMRC-NSFCC Peer Review Working Committee 2015
  • Global Alliance for Chronic Diseases Peer Review Joint Panel Member 2014
  • NHMRC Peer Review Panel Member 2012-2013
  • NHMRC Assigners Academy 2014-5
  • National Heart Foundation Research Committee Member 2005-2010

Research Invitations

  • 75th Annual Scientific Sessions American Diabetes Association, Boston, June 2015
  • Mater Medical Research Institute, Brisbane, Australia, Now 2014
  • RMIT University, Bundoora, Victoria, Australia, April, 2014
  • Joint Meeting of the Australian Vascular Biology and Australia New Zealand Microcirculation Societies, Barossa Valley, September 2013
  • National Natural Science Foundation of China- National Health and Medical Research Council Type 2 Diabetes Scientific Symposium, Canberra, Australia, June 2013
  • Baker IDI seminar series, Melbourne, November 2013
  • IBEC Satellite Symposium: Molecular regulation of muscle metabolism in exercise and insulin action. Copenhagen, Denmark, June 2012
  • University of Texas Southwestern Medical Center, Dallas, USA, May 2012
  • Laval University, Quebec, Canada, April 2012
  • Inflammation and Chronic Diseases: Arthritis and Beyond, 3rd Australia-China Biomedical Research Conference: Hobart Satellite Meeting, Hobart, Australia, April 2011
  • ISEAL, Victoria University, December, 2011
  • 9th World Congress for Microcirculation, Paris, France, September, 2010
  • UK-Physiology, Cardiff, July 2015
  • Australian Diabetes Society Annual Scientific Meeting, Sydney, Australia, September, 2010

View more on Professor Stephen Rattigan in WARP

Expertise

  • Type 2 Diabetes
  • Insulin Resistance
  • Obesity

Research Themes

Professor Rattigan's research aligns to the University's research theme of Better Health. His research has focussed on the factors that regulate glucose metabolism in skeletal muscle and have led to the important finding that blood flow regulation within muscle is critical to the normal responses to insulin. Impairment of normal blood flow distribution within muscle can lead to insulin resistance and it is his current hypothesis that such defects are the early events associated with obesity and hypertension that contribute to type 2 diabetes.

Collaboration

Prof Rattigan's expertise in regulation of muscle metabolism has led to many requests for collaborations both nationally and internationally. At present he has collaborations with research groups in Victoria University, Melbourne; University of Virginia, USA; University of Maryland; USA, Vrije University and Maastricht University, The Netherlands; University of Copenhagen, Denmark and the Liverpool John Moores University, He also provide sconsultative advice to other groups in the University of Texas, USA and University 'Magna Graecia' of Catanzaro, Italy.

Awards

  • Career Development Fellowship from National Heart Foundation (2004-7)
  • NHMRC Senior Research Fellowship 2008-2013)

Current projects

1. Microvascular dysfunction in adult offspring of type 2 diabetics

2. Role of microvascular flowmotion in skeletal muscle glucose metabolism

3. Cardiometabolic benefits of exercise training in type 2 diabetics independent of weight loss

4. Can drinking blueberry tea improve metabolic and vascular health in people with type 2 diabetes?

5. Sodium intake and microvascular-derived insulin resistance6. Role of high fat diets on inflammation

Fields of Research

  • Endocrinology (110306)
  • Cardiology (incl. Cardiovascular Diseases) (110201)
  • Systems Physiology (111603)
  • Cell Metabolism (060104)
  • Animal Physiology - Systems (060603)
  • Biochemistry and Cell Biology (060199)
  • Epidemiology (111706)
  • Medical Biochemistry: Lipids (110104)
  • Peripheral Nervous System (110905)
  • Basic Pharmacology (111501)
  • Exercise Physiology (110602)
  • Physiology (060699)
  • Agricultural Biotechnology Diagnostics (incl. Biosensors) (100101)
  • Medical Biotechnology (100499)
  • Gene and Molecular Therapy (100401)
  • Medical Biochemistry: Carbohydrates (110102)
  • Medicinal and Biomolecular Chemistry (030499)
  • Medical Biochemistry: Nucleic Acids (110105)
  • Metabolic Medicine (110107)
  • Medical and Health Sciences (119999)
  • Central Nervous System (110903)
  • Clinical Pharmacology and Therapeutics (111502)
  • Protein Trafficking (060108)
  • Cell Physiology (111601)
  • Medical Physiology (111699)
  • Preventive Medicine (111716)
  • Animal Physiology - Biophysics (060601)
  • Nutritional Physiology (111103)
  • Sensory Systems (110906)

Research Objectives

  • Diabetes (920104)
  • Cardiovascular System and Diseases (920103)
  • Health (929999)
  • Expanding Knowledge in the Environmental Sciences (970105)
  • Human Diagnostics (860802)
  • Human Pharmaceutical Treatments (e.g. Antibiotics) (860803)
  • Preventive Medicine (920412)
  • Expanding Knowledge in the Medical and Health Sciences (970111)
  • Behaviour and Health (920401)
  • Disease Distribution and Transmission (incl. Surveillance and Response) (920404)
  • Nervous System and Disorders (920111)
  • Neurodegenerative Disorders Related to Ageing (920112)
  • Health Related to Ageing (920502)
  • Endocrine Organs and Diseases (excl. Diabetes) (920106)
  • Medical Instruments (861502)
  • Diagnostic Methods (920203)
  • Reproductive System and Disorders (920114)
  • Nutrition (920411)
  • Skeletal System and Disorders (incl. Arthritis) (920116)
  • Cancer and Related Disorders (920102)

Publications

Prof Rattigan has published over 130 publications in peer reviewed journals and his work has been cited over 4,500 times. He is recognized nationally and internationally for my contributions to the vascular action of insulin in muscle and diabetes. His work appears in the major diabetes and physiology journals (Diabetes, Diabetologia, American Journal of Physiology, and Journal of Physiology) and has been the basis for a number of invited reviews (eg, Diabetes, American Journal of Physiology, Microcirculation, Essays in Biochemistry, Exercise and Sports Sciences Reviews). His work has been presented (over 180 abstracts) at numerous national and international meetings.

Total publications

180

Highlighted publications

(5 outputs)
YearTypeCitationAltmetrics
2004Journal ArticleVincent MA, Clerk LH, Lindner JR, Klibanov AL, Clark MG, et al., 'Microvascular recruitment is an early insulin effect that regulates skeletal muscle glucose uptake in vivo', Diabetes, 53, (6) pp. 1418-1423. ISSN 0012-1797 (2004) [Refereed Article]

DOI: 10.2337/diabetes.53.6.1418 [eCite] [Details]

Citations: Scopus - 279Web of Science - 277

Co-authors: Vincent MA; Clark MG

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2004Journal ArticleZhang L, Vincent MA, Richards SM, Clerk LH, Rattigan S, et al., 'Insulin sensitivity of muscle capillary recruitment in vivo', Diabetes, 53, (2) pp. 447-453. ISSN 0012-1797 (2004) [Refereed Article]

DOI: 10.2337/diabetes.53.2.447 [eCite] [Details]

Citations: Scopus - 131Web of Science - 124

Co-authors: Zhang L; Vincent MA; Richards SM; Clark MG

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2003Journal ArticleClark MG, Wallis MG, Barrett EJ, Vincent MA, Richards SM, et al., 'Blood flow and muscle metabolism: a focus on insulin action', American Journal of Physiology: Endocrinology and Metabolism, 284, (2) pp. E241-E258. ISSN 0193-1849 (2003) [Refereed Article]

DOI: 10.1152/ajpendo.00408.2002 [eCite] [Details]

Citations: Web of Science - 252

Co-authors: Clark MG; Vincent MA; Richards SM

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2002Journal ArticleVincent MA, Dawson D, Clark ADH, Lindner JR, Rattigan S, et al., 'Skeletal Muscle Microvascular Recruitment by Physiological Hyperinsulinemia Precedes Increases in Total Blood Flow', Diabetes, 51, (1) pp. 42-48. ISSN 0012-1797 (2002) [Refereed Article]

DOI: 10.2337/diabetes.51.1.42 [eCite] [Details]

Citations: Scopus - 155Web of Science - 143

Co-authors: Clark ADH; Clark MG

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2001Journal ArticleRattigan S, Wallis MG, Youd JM, Clark MG, 'Exercise Training Improves Insulin-Mediated Capillary Recruitment in Association With Glucose Uptake in Rat Hindlimb', Diabetes, 50, (12) pp. 2659-2665. ISSN 0012-1797 (2001) [Refereed Article]

DOI: 10.2337/diabetes.50.12.2659 [eCite] [Details]

Citations: Scopus - 41Web of Science - 44

Co-authors: Clark MG

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Journal Article

(111 outputs)
YearCitationAltmetrics
2019Roberts-Thomson KM, Betik AC, Premilovac D, Rattigan S, Richards SM, et al., 'Postprandial microvascular blood flow in skeletal muscle: Similarities and disparities to the hyperinsulinaemic-euglycaemic clamp', Clinical and Experimental Pharmacology and Physiology pp. 1-13. ISSN 0305-1870 (2019) [Refereed Article]

DOI: 10.1111/1440-1681.13237 [eCite] [Details]

Co-authors: Premilovac D; Richards SM; Ross RM; Keske MA

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2018Climie RED, Picone DS, Blackwood S, Keel SE, Qasem A, et al., 'Pulsatile interaction between the macro-vasculature and micro-vasculature: proof-of-concept among patients with type 2 diabetes', European Journal of Applied Physiology, 118, (11) pp. 2455-2463. ISSN 1439-6319 (2018) [Refereed Article]

DOI: 10.1007/s00421-018-3972-2 [eCite] [Details]

Citations: Scopus - 3Web of Science - 10

Co-authors: Climie RED; Picone DS; Blackwood S; Sharman JE

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2018Hu D, Remash D, Russell RD, Greenaway T, Rattigan S, et al., 'Impairments in adipose tissue microcirculation in Type 2 diabetes mellitus assessed by real-time contrast-enhanced ultrasound', Circulation: Cardiovascular Imaging, 11, (4) Article e007074. ISSN 1942-0080 (2018) [Refereed Article]

DOI: 10.1161/CIRCIMAGING.117.007074 [eCite] [Details]

Citations: Scopus - 4Web of Science - 5

Co-authors: Remash D; Russell RD; Greenaway T; Squibb KA; Jones G; Premilovac D; Richards SM; Keske MA

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2018Hu D, Russell RD, Remash D, Greenaway T, Rattigan S, et al., 'Are the metabolic benefits of resistance training in type 2 diabetes linked to improvements in adipose tissue microvascular blood flow?', American Journal of Physiology: Endocrinology and Metabolism, 315, (6) pp. E1242-E1250. ISSN 0193-1849 (2018) [Refereed Article]

DOI: 10.1152/ajpendo.00234.2018 [eCite] [Details]

Citations: Scopus - 1

Co-authors: Russell RD; Remash D; Greenaway T; Squibb KA; Jones G; Ross RM; Premilovac D; Richards SM; Keske MA

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2018Premilovac D, Attrill E, Rattigan S, Richards SM, Kim J, et al., 'Acute, local infusion of angiotensin II impairs microvascular and metabolic insulin sensitivity in skeletal muscle', Cardiovascular Research pp. 1-12. ISSN 0008-6363 (2018) [Refereed Article]

DOI: 10.1093/cvr/cvy225 [eCite] [Details]

Citations: Scopus - 3Web of Science - 6

Co-authors: Premilovac D; Richards SM; Keske MA

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2018Russell RD, Hu D, Greenaway T, Sharman JE, Rattigan S, et al., 'Oral glucose challenge impairs skeletal muscle microvascular blood flow in healthy people', American Journal of Physiology - Endocrinology and Metabolism, 315, (2) pp. E307-E315. ISSN 0193-1849 (2018) [Refereed Article]

DOI: 10.1152/ajpendo.00448.2017 [eCite] [Details]

Citations: Scopus - 4Web of Science - 5

Co-authors: Russell RD; Greenaway T; Sharman JE; Richards SM; Keske MA

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2017Blackwood SJ, Dwyer RM, Bradley EA, Keske MA, Richards SM, et al., 'Determination of skeletal muscle microvascular flowmotion with contrast-enhanced ultrasound', Ultrasound in Medicine and Biology, 43, (9) pp. 2013-2023. ISSN 0301-5629 (2017) [Refereed Article]

DOI: 10.1016/j.ultrasmedbio.2017.05.012 [eCite] [Details]

Citations: Scopus - 6Web of Science - 6

Co-authors: Blackwood SJ; Dwyer RM; Bradley EA; Keske MA; Richards SM

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2017Keske MA, Dwyer RM, Russell RD, Blackwood SJ, Brown AA, et al., 'Regulation of microvascular flow and metabolism: An overview', Clinical and Experimental Pharmacology and Physiology, 44, (1) pp. 143-149. ISSN 0305-1870 (2017) [Refereed Article]

DOI: 10.1111/1440-1681.12688 [eCite] [Details]

Citations: Scopus - 10Web of Science - 10

Co-authors: Keske MA; Dwyer RM; Russell RD; Blackwood SJ; Brown AA; Premilovac D; Richards SM

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2017Ng HLH, Premilovac D, Rattigan S, Richards SM, Muniyappa R, et al., 'Acute vascular and metabolic actions of the green tea polyphenol epigallocatechin 3-gallate in rat skeletal muscle', Journal of Nutritional Biochemistry, 40 pp. 23-31. ISSN 0955-2863 (2017) [Refereed Article]

DOI: 10.1016/j.jnutbio.2016.10.005 [eCite] [Details]

Citations: Scopus - 5Web of Science - 4

Co-authors: Ng HLH; Premilovac D; Richards SM; Keske MA

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2017Russell RD, Hu D, Greenaway T, Blackwood SJ, Dwyer RM, et al., 'Skeletal muscle microvascular-linked improvements in glycemic control from resistance training in individuals with Type 2 Diabetes', Diabetes Care, 40, (9) pp. 1256-1263. ISSN 0149-5992 (2017) [Refereed Article]

DOI: 10.2337/dc16-2750 [eCite] [Details]

Citations: Scopus - 19Web of Science - 17

Co-authors: Russell RD; Greenaway T; Blackwood SJ; Dwyer RM; Sharman JE; Jones G; Squibb KA; Brown AA; Otahal P; Al-Aubaidy H; Premilovac D; Hitchins S; Richards SM; Keske MA

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2017Sjoberg KA, Frosig C, Kjobsted R, Sylow L, Kleinert M, et al., 'Exercise increases human skeletal muscle insulin sensitivity via coordinated increases in microvascular perfusion and molecular signaling', Diabetes, 66, (6) pp. 1501-1510. ISSN 0012-1797 (2017) [Refereed Article]

DOI: 10.2337/db16-1327 [eCite] [Details]

Citations: Scopus - 50Web of Science - 43

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2017Zhang X, Hiam D, Hong YH, Zulli A, Hayes A, et al., 'Nitric oxide is required for the insulin sensitizing effects of contraction in mouse skeletal muscle', Journal of Physiology, 595, (24) pp. 7427-7439. ISSN 0022-3751 (2017) [Refereed Article]

DOI: 10.1113/JP275133 [eCite] [Details]

Citations: Scopus - 3Web of Science - 3

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2016Keske MA, Premilovac D, Bradley EA, Dwyer RM, Richards SM, et al., 'Muscle microvascular blood flow responses in insulin resistance and ageing', The Journal of Physiology, 594, (8) pp. 2223-2231. ISSN 1469-7793 (2016) [Refereed Article]

DOI: 10.1113/jphysiol.2014.283549 [eCite] [Details]

Citations: Scopus - 24Web of Science - 28

Co-authors: Keske MA; Premilovac D; Bradley EA; Dwyer RM; Richards SM

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2015Bradley EA, Zhang L, Genders AJ, Richards SM, Rattigan S, et al., 'Enhancement of insulin-mediated rat muscle glucose uptake and microvascular perfusion by 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside', Cardiovascular Diabetology, 14, (1) Article 91. ISSN 1475-2840 (2015) [Refereed Article]

DOI: 10.1186/s12933-015-0251-y [eCite] [Details]

Citations: Scopus - 4Web of Science - 5

Co-authors: Bradley EA; Richards SM; Keske MA

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2015Hong YH, Betik AC, Premilovac D, Dwyer RM, Keske MA, et al., 'No effect of NOS inhibition on skeletal muscle glucose uptake during in situ hindlimb contraction in healthy and diabetic Sprague-Dawley rats', American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 308, (10) pp. R862-R871. ISSN 0363-6119 (2015) [Refereed Article]

DOI: 10.1152/ajpregu.00412.2014 [eCite] [Details]

Citations: Scopus - 8Web of Science - 8

Co-authors: Premilovac D; Dwyer RM; Keske MA

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2015Hong YH, Frugier T, Zhang X, Murphy RM, Lynch GS, et al., 'Glucose uptake during contraction in isolated skeletal muscles from neuronal nitric oxide synthase μ knockout mice', Journal of Applied Physiology, 118, (9) pp. 1113-1121. ISSN 8750-7587 (2015) [Refereed Article]

DOI: 10.1152/japplphysiol.00056.2015 [eCite] [Details]

Citations: Scopus - 12Web of Science - 11

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2015Keske MA, Ng HLH, Premilovac D, Rattigan S, Kim J, et al., 'Vascular and metabolic actions of the green tea polyphenol epigallocatechin gallate', Current Medicinal Chemistry, 22, (1) pp. 59-69. ISSN 0929-8673 (2015) [Refereed Article]

PMID: 25312214 [eCite] [Details]

Citations: Scopus - 43Web of Science - 44

Co-authors: Keske MA; Ng HLH; Premilovac D

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2015Sjoberg KA, Rattigan S, Jeppesen JF, Lundsgaard A-M, Holst JJ, et al., 'Differential effects of glucagon-like peptide-1 on microvascular recruitment and glucose metabolism in short- and long-term insulin resistance', Journal of Physiology, 593, (9) pp. 2185-2198. ISSN 0022-3751 (2015) [Refereed Article]

DOI: 10.1113/JP270129 [eCite] [Details]

Citations: Scopus - 17Web of Science - 15

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2014Barrett EJ, Keske MA, Rattigan S, Eringa EC, 'Rebuttal from Eugene J. Barrett, Michelle A. Keske, Stephen Rattigan and Etto C. Eringa', The Journal of physiology, 592, (23) pp. 5137-5138. ISSN 0022-3751 (2014) [Contribution to Refereed Journal]

DOI: 10.1113/jphysiol.2014.284604 [eCite] [Details]

Citations: Scopus - 1Web of Science - 1

Co-authors: Keske MA

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2014Barrett EJ, Keske MA, Rattigan S, Eringa EC, 'CrossTalk proposal: De novo capillary recruitment in healthy muscle is necessary', Journal of Physiology, 592, (23) pp. 5129-5131. ISSN 0022-3751 (2014) [Refereed Article]

DOI: 10.1113/jphysiol.2014.282137 [eCite] [Details]

Citations: Scopus - 7Web of Science - 7

Co-authors: Keske MA

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2014Premilovac D, Richards SM, Rattigan S, Keske MA, 'A vascular mechanism for high-sodium-induced insulin resistance in rats', Diabetologia: Clinical and Experimental Diabetes and Metabolism, 57, (12) pp. 2586-2595. ISSN 0012-186X (2014) [Refereed Article]

DOI: 10.1007/s00125-014-3373-y [eCite] [Details]

Citations: Scopus - 18Web of Science - 19

Co-authors: Premilovac D; Richards SM; Keske MA

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2014Sjoberg KA, Holst JJ, Rattigan S, Richter EA, Kiens B, 'GLP-1 increases microvascular recruitment but not glucose uptake in human and rat skeletal muscle', American Journal of Physiology: Endocrinology and Metabolism, 306, (4) pp. E355-E362. ISSN 0193-1849 (2014) [Refereed Article]

DOI: 10.1152/ajpendo.00283.2013 [eCite] [Details]

Citations: Scopus - 35Web of Science - 36

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2013Bradley EA, Richards SM, Keske MA, Rattigan S, 'Local NOS inhibition impairs vascular and metabolic actions of insulin in rat hindleg muscle in vivo', American Journal of Physiology: Endocrinology and Metabolism, 305, (6) pp. E745-E750. ISSN 0193-1849 (2013) [Refereed Article]

DOI: 10.1152/ajpendo.00289.2013 [eCite] [Details]

Citations: Scopus - 22Web of Science - 23

Co-authors: Bradley EA; Richards SM; Keske MA

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2013Jacobson GA, Yee KC, Premilovac D, Rattigan S, 'Enantioselective disposition of (R/S)-albuterol in skeletal and cardiac muscle', Drug Testing and Analysis, 6, (6) pp. 563-567. ISSN 1942-7603 (2013) [Refereed Article]

DOI: 10.1002/dta.1575 [eCite] [Details]

Citations: Scopus - 13Web of Science - 13

Co-authors: Jacobson GA; Yee KC; Premilovac D

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2013Keith LJ, Rattigan S, Keske MA, Jose M, Sharman JE, 'Exercise aortic stiffness: Reproducibility and relation to end-organ damage in men', Journal of Human Hypertension, 27, (8) pp. 516-522. ISSN 0950-9240 (2013) [Refereed Article]

DOI: 10.1038/jhh.2013.5 [eCite] [Details]

Citations: Scopus - 9Web of Science - 8

Co-authors: Keith LJ; Keske MA; Jose M; Sharman JE

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2013Premilovac D, Bradley EA, Ng HLH, Richards SM, Rattigan S, et al., 'Muscle insulin resistance resulting from impaired microvascular insulin sensitivity in Sprague Dawley rats', Cardiovascular Research, 98, (1) pp. 28-36. ISSN 0008-6363 (2013) [Refereed Article]

DOI: 10.1093/cvr/cvt015 [eCite] [Details]

Citations: Scopus - 25Web of Science - 24

Co-authors: Premilovac D; Bradley EA; Ng HLH; Richards SM; Keske MA

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2013Premilovac D, Roberts-Thompson KM, Ng HLH, Bradley EA, Richards SM, et al., 'Blueberry tea enhances insulin sensitivity by augmenting insulin-mediated metabolic and microvascular responses in skeletal muscle of high fat fed rats', International Journal of Diabetology & Vascular Disease Research, 1, (8) pp. 1-10. ISSN 2328-353X (2013) [Non Refereed Article]

[eCite] [Details]

Co-authors: Premilovac D; Ng HLH; Bradley EA; Richards SM; Keske MA

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2013Rattigan S, Richards SM, Keske MA, 'Microvascular contributions to insulin resistance', Diabetes, 62, (2) pp. 343-345. ISSN 0012-1797 (2013) [Contribution to Refereed Journal]

DOI: 10.2337/db12-1193 [eCite] [Details]

Citations: Scopus - 10Web of Science - 10

Co-authors: Richards SM; Keske MA

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2012Barrett EJ, Rattigan S, 'Muscle perfusion: its measurement and role in metabolic regulation', Diabetes, 61, (11) pp. 2661-2668. ISSN 0012-1797 (2012) [Refereed Article]

DOI: 10.2337/db12-0271 [eCite] [Details]

Citations: Scopus - 26Web of Science - 29

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2012McConell GK, Rattigan S, Lee-Young RS, Wadley GD, Merry TL, 'Skeletal muscle nitric oxide signaling and exercise: a focus on glucose metabolism', American Journal of Physiology: Endocrinology and Metabolism, 303, (3) pp. E301-E307. ISSN 0193-1849 (2012) [Refereed Article]

DOI: 10.1152/ajpendo.00667.2011 [eCite] [Details]

Citations: Scopus - 49Web of Science - 48

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2012Meijer RI, De Boer MP, Groen MR, Eringa EC, Rattigan S, et al., 'Insulin-induced microvascular recruitment in skin and muscle are related and both are associated with whole-body glucose uptake', Microcirculation, 19, (6) pp. 494-500. ISSN 1073-9688 (2012) [Refereed Article]

DOI: 10.1111/j.1549-8719.2012.00174.x [eCite] [Details]

Citations: Scopus - 48Web of Science - 49

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2012St-Pierre P, Keith LJ, Richards SM, Rattigan S, Keske MA, 'Microvascular blood flow responses to muscle contraction are not altered by high-fat feeding in rats', Diabetes, Obesity and Metabolism, 14, (8) pp. 753-761. ISSN 1462-8902 (2012) [Refereed Article]

DOI: 10.1111/j.1463-1326.2012.01598.x [eCite] [Details]

Citations: Scopus - 10Web of Science - 12

Co-authors: Keith LJ; Richards SM; Keske MA

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2011Bussey CT, Kolka CM, Rattigan S, Richards SM, 'Adiponectin opposes endothelin-1-mediated vasoconstriction in the perfused rat hindlimb', American Journal of Physiology: Heart and Circulatory Physiology, 301, (1) pp. H79-H86. ISSN 0363-6135 (2011) [Refereed Article]

DOI: 10.1152/ajpheart.00864.2010 [eCite] [Details]

Citations: Scopus - 19Web of Science - 21

Co-authors: Bussey CT; Kolka CM; Richards SM

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2011Genders AJ, Bradley EA, Rattigan S, Richards SM, 'cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle', American Journal of Physiology: Endocrinology and Metabolism, 301, (2) pp. E342-E350. ISSN 0193-1849 (2011) [Refereed Article]

DOI: 10.1152/ajpendo.00691.2010 [eCite] [Details]

Citations: Scopus - 10Web of Science - 9

Co-authors: Genders AJ; Bradley EA; Richards SM

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2011Sjoberg KA, Rattigan S, Hiscock N, Richter EA, Kiens B, 'A new method to study changes in microvascular blood volume in muscle and adipose tissue: real-time imaging in humans and rat', American Journal of Physiology: Heart and Circulatory Physiology, 301, (2) pp. H450-H458. ISSN 0363-6135 (2011) [Refereed Article]

DOI: 10.1152/ajpheart.01174.2010 [eCite] [Details]

Citations: Scopus - 47Web of Science - 50

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2010Bradley EA, Eringa EC, Stehouwer CDA, Korstjens I, van Nieuw Amerongen GP, et al., 'Activation of AMP-Activated Protein Kinase by 5-Aminoimidazole-4-Carboxamide-1-β-D-Ribofuranoside in the Muscle Microcirculation Increases Nitric Oxide Synthesis and Microvascular Perfusion', Arteriosclerosis, Thrombosis, and Vascular Biology, 30, (6) pp. 1137-1142. ISSN 1079-5642 (2010) [Refereed Article]

DOI: 10.1161/ATVBAHA.110.204404 [eCite] [Details]

Citations: Scopus - 51Web of Science - 52

Co-authors: Bradley EA; Clark MG

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2010Bradley EA, Willson KJ, Choi-Lundberg D, Clark MG, Rattigan S, 'Effects of central administration of insulin or L-NMMA on rat skeletal muscle microvascular perfusion', Diabetes Obesity & Metabolism, 12, (10) pp. 900-908. ISSN 1462-8902 (2010) [Refereed Article]

DOI: 10.1111/j.1463-1326.2010.01253.x [eCite] [Details]

Citations: Scopus - 6Web of Science - 6

Co-authors: Bradley EA; Willson KJ; Choi-Lundberg D; Clark MG

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2010Merry TL, Dwyer RM, Bradley EA, Rattigan S, McConell GK, 'Local hindlimb antioxidant infusion does not affect muscle glucose uptake during in situ contractions in rat', Journal of Applied Physiology, 108, (5) pp. 1275-1283. ISSN 8750-7587 (2010) [Refereed Article]

DOI: 10.1152/japplphysiol.01335.2009 [eCite] [Details]

Citations: Scopus - 18Web of Science - 16

Co-authors: Dwyer RM; Bradley EA

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2010Merry TL, Wadley GD, Stathis CG, Garnham AP, Rattigan S, et al., 'N Acetylcysteine infusion does not affect glucose disposal during prolonged moderate-intensity exercise in humans', Journal of Physiology, 588, (9) pp. 1623-1634. ISSN 0022-3751 (2010) [Refereed Article]

DOI: 10.1113/jphysiol.2009.184333 [eCite] [Details]

Citations: Scopus - 31Web of Science - 28

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2010St Pierre P, Genders AJ, Keske MA, Richards SM, Rattigan S, 'Loss of insulin-mediated microvascular perfusion in skeletal muscle is associated with the development of insulin resistance ', Diabetes Obesity & Metabolism, 12, (9) pp. 798-805. ISSN 1462-8902 (2010) [Refereed Article]

DOI: 10.1111/j.1463-1326.2010.01235.x [eCite] [Details]

Citations: Scopus - 27Web of Science - 26

Co-authors: Genders AJ; Keske MA; Richards SM

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2009Newman JMB, Dwyer RM, St Pierre P, Richards SM, Clark MG, et al., 'Decreased microvascular vasomotion and myogenic response in rat skeletal muscle in association with acute insulin resistance', Journal of Physiology, 587, (11) pp. 2579-2588. ISSN 0022-3751 (2009) [Refereed Article]

DOI: 10.1113/jphysiol.2009.169011 [eCite] [Details]

Citations: Scopus - 52Web of Science - 47

Co-authors: Newman JMB; Dwyer RM; Richards SM; Clark MG

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2009Yuen DYC, Dwyer RM, Matthews VB, Zhang L, Drew BG, et al., 'Interleukin-6 attenuates insulin-mediated increases in endothelial cell signaling but augments skeletal muscle insulin action via differential effects on tumor necrosis factor-a expression', Diabetes, 58, (May) pp. 1086-1095. ISSN 0012-1797 (2009) [Refereed Article]

DOI: 10.2337/db08-0775 [eCite] [Details]

Citations: Scopus - 37Web of Science - 34

Co-authors: Dwyer RM; Zhang L; Clark MG

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2008Clark MG, Rattigan S, Barrett EJ, Keske MAV, 'Point: Counterpoint: There is/is not capillary recruitment in active skeletal muscle during exercise', Journal of Appliedy Physiology, 104, (3) pp. 889-891. ISSN 8750-7587 (2008) [Contribution to Refereed Journal]

DOI: 10.1152/japplphysiol.00779.2007 [eCite] [Details]

Citations: Scopus - 46Web of Science - 42

Co-authors: Clark MG; Keske MAV

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2008Clark MG, Rattigan S, Barrett EJ, Keske MAV, 'Last word on Point:Counterpoint: There is/is not capillary recruitment in active skeletal muscle during exercise', Journal of Applied Physiology, 104, (3) pp. 900. ISSN 8750-7587 (2008) [Contribution to Refereed Journal]

DOI: 10.1152/japplphysiol.01318.2007 [eCite] [Details]

Citations: Scopus - 6Web of Science - 4

Co-authors: Clark MG; Keske MAV

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2008Ross RM, Downey KA, Newman JMB, Richards SM, Clark MG, et al., 'Contrast-enhanced ultrasound measurement of microvascular perfusion relevant to nutrient and hormone delivery in skeletal muscle: A model study in vitro', Microvascular Research, 75, (3) pp. 323-329. ISSN 0026-2862 (2008) [Refereed Article]

DOI: 10.1016/j.mvr.2007.11.002 [eCite] [Details]

Citations: Scopus - 11Web of Science - 11

Co-authors: Ross RM; Downey KA; Newman JMB; Richards SM; Clark MG

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2007Bradley EA, Clark MG, Rattigan S, 'Acute effects of wortmannin on insulin's hemodynamic and metabolic actions in vivo', American Journal of Physiology: Endocrinology and Metabolism, 292, (3) pp. E779-E787. ISSN 0193-1849 (2007) [Refereed Article]

DOI: 10.1152/ajpendo.00407.2006 [eCite] [Details]

Citations: Scopus - 12Web of Science - 10

Co-authors: Bradley EA; Clark MG

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2007Clark MG, Rattigan S, Barrett EJ, Vincent MA, 'There is / is not capillary recruitment in active skeletal muscle during exercise', Journal of Applied Physiology, 104, (3) pp. 889-891. ISSN 8750-7587 (2007) [Non Refereed Article]

DOI: 10.1152/japplphysiol.00779.2007 [eCite] [Details]

Citations: Scopus - 46Web of Science - 42

Co-authors: Clark MG

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2007Kolka CM, Rattigan S, Richards SM, Clark MG, 'Potential for endothelin-1-mediated impairment of contractile activity in hypertension', Clinical and Experimental Physiology and Pharmacology, 34, (3) pp. 217-222. ISSN 0305-1870 (2007) [Refereed Article]

DOI: 10.1111/j.1440-1681.2007.04575.x [eCite] [Details]

Citations: Scopus - 1Web of Science - 5

Co-authors: Kolka CM; Richards SM; Clark MG

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2007Newman JMB, Ross RM, Richards SM, Clark MG, Rattigan S, 'Insulin and contraction increase nutritive blood flow in rat muscle in vivo: determined by microdialysis of L-[14C]glucose', Journal of Physiology, 585, (1) pp. 217-229. ISSN 0022-3751 (2007) [Refereed Article]

DOI: 10.1113/jphysiol.2007.138818 [eCite] [Details]

Citations: Scopus - 15Web of Science - 14

Co-authors: Newman JMB; Ross RM; Richards SM; Clark MG

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2007Rattigan S, Bussey CT, Ross RM, Richards SM, 'Obesity, Insulin Resistance, and Capillary Recruitment', Microcirculation, 14, (4-5) pp. 299-309. ISSN 1073-9688 (2007) [Refereed Article]

DOI: 10.1080/10739680701282796 [eCite] [Details]

Citations: Scopus - 25Web of Science - 22

Co-authors: Bussey CT; Ross RM; Richards SM

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2007Ross RM, Kolka CM, Rattigan S, Clark MG, 'Acute blockade by endothelin-1 of haemodynamic insulin action in rats', Diabetologia, 50, (2) pp. 443-451. ISSN 0012-186X (2007) [Refereed Article]

DOI: 10.1007/s00125-006-0525-8 [eCite] [Details]

Citations: Scopus - 28Web of Science - 25

Co-authors: Ross RM; Kolka CM; Clark MG

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2007Ross RM, Wadley GD, Clark MG, Rattigan S, McConell GK, 'Local nitric oxide synthase inhibition reduces skeletal muscle glucose uptake but not capillary blood flow during in situ muscle contraction in rats', Diabetes, 56, (12) pp. 2885-2892. ISSN 0012-1797 (2007) [Refereed Article]

DOI: 10.2337/db07-0745 [eCite] [Details]

Citations: Scopus - 54Web of Science - 54

Co-authors: Ross RM; Clark MG

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2007Vollus GC, Bradley EA, Roberts NK, Newman JMB, Richards SM, et al., 'Graded occlusion of perfused rat muscle vasculature decreases insulin action', Clinical Science, 112, (8) pp. 457-466. ISSN 0143-5221 (2007) [Refereed Article]

DOI: 10.1042/CS20060311 [eCite] [Details]

Citations: Scopus - 16Web of Science - 13

Co-authors: Vollus GC; Bradley EA; Roberts NK; Newman JMB; Richards SM; Clark MG

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2006Clark MG, Rattigan S, Barrett EJ, 'Nutritive blood flow as an essential element supporting muscle anabolism', Current Opinion in Clinical Nutrition and Metabolic Care, 9, (3) pp. 185-189. ISSN 1363-1950 (2006) [Refereed Article]

DOI: 10.1097/01.mco.0000222097.90890.c2 [eCite] [Details]

Citations: Scopus - 65Web of Science - 26

Co-authors: Clark MG

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2006Mahajan H, Kolka CM, Newman JMB, Rattigan S, Richards SM, et al., 'Vascular and metabolic effects of methacholine in relation to insulin action in muscle', Diabetologia, 49, (4) pp. 713-723. ISSN 0012-186X (2006) [Refereed Article]

DOI: 10.1007/s00125-005-0110-6 [eCite] [Details]

Citations: Scopus - 4Web of Science - 3

Co-authors: Mahajan H; Kolka CM; Newman JMB; Richards SM; Clark MG

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2006Rattigan S, Bradley EA, Richards SM, Clark MG, 'Muscle metabolism and control of capillary blood flow: insulin and exercise', Essays in Biochemistry, 42, (1) pp. 133-144. ISSN 0071-1365 (2006) [Refereed Article]

DOI: 10.1042/bse0420133 [eCite] [Details]

Citations: Scopus - 9Web of Science - 8

Co-authors: Bradley EA; Richards SM; Clark MG

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2006Rattigan S, Zhang L, Mahajan H, Kolka CM, Richards SM, et al., 'Factors influencing the hemodynamic and metabolic effects of insulin in muscle', Current Diabetes Reviews, 2, (1) pp. 61-70. ISSN 1573-3998 (2006) [Refereed Article]

DOI: 10.2174/157339906775473653 [eCite] [Details]

Citations: Scopus - 8

Co-authors: Zhang L; Mahajan H; Kolka CM; Richards SM; Clark MG

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2005Kolka CM, Rattigan S, Richards SM, Barrett EJ EJ, Clark MG, 'Endothelial Na+ -D-glucose cotransporter: No Role in Insulin-mediated Glucose Uptake ', Hormone and Metabolic Research, 37, (11) pp. 657-661. ISSN 0018-5043 (2005) [Refereed Article]

DOI: 10.1055/s-2005-870574 [eCite] [Details]

Citations: Scopus - 2Web of Science - 2

Co-authors: Kolka CM; Richards SM; Clark MG

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2005Kolka CM, Rattigan S, Richards SM, Clark MG, 'Metabolic and vascular actions of endothelin-1 are inhibited by insulin-mediated vasodilation in perfused rat hindlimb muscle', British Journal of Pharmacology, 145, (7) pp. 992-1000. ISSN 0007-1188 (2005) [Refereed Article]

DOI: 10.1038/sj.bjp.0706263 [eCite] [Details]

Citations: Scopus - 15Web of Science - 16

Co-authors: Kolka CM; Richards SM; Clark MG

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2005Rattigan S, Wheatley C, Richards SM, Barrett EJ, Clark MG, 'Exercise and insulin-mediated capillary recruitment in muscle', Exercise and Sport Sciences Reviews, 33, (1) pp. 43-48. ISSN 0091-6331 (2005) [Refereed Article]

PMID: 15640720 [eCite] [Details]

Citations: Scopus - 23Web of Science - 26

Co-authors: Richards SM

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2005Roberts JL, Newman JMB, Warner RC, Rattigan S, Clark MG, 'Axially symmetric semi-infinite domain models of microdialysis and their application to the determination of nutritive flow in rat muscle', Journal of Physiology, 563, (1) pp. 213-228. ISSN 0022-3751 (2005) [Refereed Article]

DOI: 10.1113/jphysiol.2003.056531 [eCite] [Details]

Citations: Scopus - 4Web of Science - 4

Co-authors: Roberts JL; Newman JMB; Warner RC; Clark MG

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2005Vincent MA, Clerk LH, Rattigan S, Clark MG, Barrett EJ, 'Active role for the vasculature in the delivery of insulin to skeletal muscle', Clinical and Experimental Pharmacology and Physiology, 32, (4) pp. 302-307. ISSN 0305-1870 (2005) [Refereed Article]

DOI: 10.1111/j.1440-1681.2005.04188.x [eCite] [Details]

Citations: Scopus - 55Web of Science - 52

Co-authors: Vincent MA

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2005Wallis MG, Smith ME, Kolka CM, Zhang L, Richards SM, et al., 'Acute glucosamine-induced insulin resistance in muscle in vivo is associated with impaired capillary recruitment', Diabetologia, 48, (10) pp. 2131-2139. ISSN 0012-186X (2005) [Refereed Article]

DOI: 10.1007/s00125-005-1887-z [eCite] [Details]

Citations: Scopus - 27Web of Science - 25

Co-authors: Smith ME; Kolka CM; Zhang L; Richards SM; Clark MG

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2005Zhang L, Newman JMB, Richards SM, Rattigan S, Clark MG, 'Microvascular flow routes in muscle controlled by vasoconstrictors', Microvascular Research, 70, (1) pp. 7-16. ISSN 0026-2862 (2005) [Refereed Article]

DOI: 10.1016/j.mvr.2005.06.001 [eCite] [Details]

Citations: Scopus - 13Web of Science - 11

Co-authors: Zhang L; Newman JMB; Richards SM; Clark MG

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2004Clerk LC, Vincent MA, Lindner J, Clark MG, Rattigan S, et al., 'The vasodilatory actions of insulin on resistance and terminal arterioles and their impact on muscle glucose uptake', Diabetes/Metabolism Reseach and Reviews, 20, (1) pp. 3-12. ISSN 1520-7552 (2004) [Refereed Article]

DOI: 10.1002/dmrr.414 [eCite] [Details]

Citations: Scopus - 83Web of Science - 76

Co-authors: Vincent MA; Clark MG

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2004Mahajan H, Richards SM, Rattigan S, Clark MG, 'Local methacholine but not bradykinin potentiates insulin-mediated capillary recruitment and glucose uptake in muscle in vivo', Diabetologia, 47, (12) pp. 2226-2234. ISSN 0012-186X (2004) [Refereed Article]

DOI: 10.1007/s00125-004-1580-7 [eCite] [Details]

Citations: Scopus - 18Web of Science - 15

Co-authors: Mahajan H; Richards SM; Clark MG

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2004Vincent MA, Clerk LH, Lindner JR, Klibanov AL, Clark MG, et al., 'Microvascular recruitment is an early insulin effect that regulates skeletal muscle glucose uptake in vivo', Diabetes, 53, (6) pp. 1418-1423. ISSN 0012-1797 (2004) [Refereed Article]

DOI: 10.2337/diabetes.53.6.1418 [eCite] [Details]

Citations: Scopus - 279Web of Science - 277

Co-authors: Vincent MA; Clark MG

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2004Wheatley CM, Rattigan S, Richards SM, Barrett EJ, Clark MG, 'Skeletal muscle contraction stimulates capillary recruitment and glucose uptake in insulin resistant obese Zucker rats', American Journal of Physiology - Endocrinology and Metabolism, 287, (4) pp. E804-E807. ISSN 0193-1849 (2004) [Refereed Article]

DOI: 10.1152/ajpendo.00077.2004 [eCite] [Details]

Citations: Scopus - 45Web of Science - 48

Co-authors: Richards SM; Clark MG

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2004Zhang L, Vincent MA, Richards SM, Clerk LH, Rattigan S, et al., 'Insulin sensitivity of muscle capillary recruitment in vivo', Diabetes, 53, (2) pp. 447-453. ISSN 0012-1797 (2004) [Refereed Article]

DOI: 10.2337/diabetes.53.2.447 [eCite] [Details]

Citations: Scopus - 131Web of Science - 124

Co-authors: Zhang L; Vincent MA; Richards SM; Clark MG

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2003Clark MG, Wallis MG, Barrett EJ, Vincent MA, Richards SM, et al., 'Blood flow and muscle metabolism: a focus on insulin action', American Journal of Physiology: Endocrinology and Metabolism, 284, (2) pp. E241-E258. ISSN 0193-1849 (2003) [Refereed Article]

DOI: 10.1152/ajpendo.00408.2002 [eCite] [Details]

Citations: Web of Science - 252

Co-authors: Clark MG; Vincent MA; Richards SM

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2003Clerk LH, Smith ME, Rattigan S, Clark MG, 'Nonnutritive flow impairs uptake of fatty acids by white muscles of the perfused rat hindlimb', American Journal of Physiology: Endocrinology and Metabolism, 284, (3 47-3) pp. E611-E617. ISSN 0193-1849 (2003) [Refereed Article]

DOI: 10.1152/ajpendo.00153.2002 [eCite] [Details]

Citations: Scopus - 8Web of Science - 7

Co-authors: Smith ME; Clark MG

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2003Mahajan H, Richards SM, Rattigan S, Clark MG, 'T-1032, a cyclic GMP phosphodiesterase-5 inhibitor, acutely blocks physiologic insulin-mediated muscle haemodynamic effects and glucose uptake in vivo', British Journal of Pharmacology, 140, (7) pp. 1283-1291. ISSN 0007-1188 (2003) [Refereed Article]

DOI: 10.1038/sj.bjp.0705548 [eCite] [Details]

Citations: Scopus - 8Web of Science - 7

Co-authors: Mahajan H; Richards SM; Clark MG

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2003Rattigan S, Barrett EJ, Clark MG, 'Insulin-mediated Capillary Recruitment in Skeletal Muscle: Is This a Mediator of Insulin Action on Glucose Metabolism?', Current Diabetes Reports, 3, (3) pp. 195-200. ISSN 1534-4827 (2003) [Non Refereed Article]

DOI: 10.1007/s11892-003-0063-4 [eCite] [Details]

Citations: Scopus - 12

Co-authors: Clark MG

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2003Vincent MA, Barrett EJ, Lindner JR, Clark MG, Rattigan S, 'Inhibiting NOS blocks microvascular recruitment and blunts muscle glucose uptake in response to insulin', American Journal of Physiology: Endocrinology and Metabolism, 285, (1 48-1) pp. E123-E129. ISSN 0193-1849 (2003) [Refereed Article]

DOI: 10.1152/ajpendo.00021.2003 [eCite] [Details]

Citations: Scopus - 228Web of Science - 221

Co-authors: Vincent MA; Clark MG

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2003Zhang L, Wheatley CM, Richards SM, Barrett EJ, Clark MG, et al., 'TNFalpha acutely inhibits vascular effects of physiological but not high insulin or contraction', American Journal of Physiology: Endocrinology and Metabolism, 285, (3 ) pp. E654-E660. ISSN 0193-1849 (2003) [Refereed Article]

DOI: 10.1152/ajpendo.00119.2003 [eCite] [Details]

Citations: Scopus - 44Web of Science - 46

Co-authors: Zhang L; Richards SM; Clark MG

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2002Clark MG, Barrett EJ, Wallis MG, Vincent MA, Rattigan S, 'The Microvasculature in Insulin Resistance and Type 2 Diabetes', Seminars in Vascular Medicine, 2, (1) pp. 21-31. ISSN 1528-9648 (2002) [Refereed Article]

DOI: 10.1055/s-2002-23506 [eCite] [Details]

Citations: Scopus - 33

Co-authors: Clark MG

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2002Clerk LH, Rattigan S, Clark MG, 'Lipid Infusion Impairs Physiologic Insulin-Mediated Capillary Recruitment and Muscle Glucose Uptake In Vivo', Diabetes, 51, (4) pp. 1138-1145. ISSN 0012-1797 (2002) [Refereed Article]

DOI: 10.2337/diabetes.51.4.1138 [eCite] [Details]

Citations: Scopus - 129Web of Science - 119

Co-authors: Clark MG

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2002DiMaria CA, Rattigan S, Clark MG, 'Vasoconstrictor-mediated thermogenesis present in perfused skeletal muscle but absent from perfused heart', Journal of Thermal Biology, 27, (2) pp. 151-158. ISSN 0306-4565 (2002) [Refereed Article]

DOI: 10.1016/S0306-4565(01)00078-X [eCite] [Details]

Citations: Scopus - 2Web of Science - 2

Co-authors: Clark MG

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2002Newman JMB, Rattigan S, Clark MG, 'Nutritive blood flow improves interstitial glucose and lactate exchange in perfused rat hindlimb', American Journal of Physiology - Heart and Circulatory Physiology, 283, (1) pp. H186-H192. ISSN 0363-6135 (2002) [Refereed Article]

DOI: 10.1152/ajpheart.01024.2001 [eCite] [Details]

Citations: Web of Science - 16

Co-authors: Newman JMB; Clark MG

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2002Vincent MA, Dawson D, Clark ADH, Lindner JR, Rattigan S, et al., 'Skeletal Muscle Microvascular Recruitment by Physiological Hyperinsulinemia Precedes Increases in Total Blood Flow', Diabetes, 51, (1) pp. 42-48. ISSN 0012-1797 (2002) [Refereed Article]

DOI: 10.2337/diabetes.51.1.42 [eCite] [Details]

Citations: Scopus - 155Web of Science - 143

Co-authors: Clark ADH; Clark MG

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2002Wallis MG, Wheatley C, Rattigan S, Barrett EJ, Clark ADH, et al., 'Insulin-Mediated Hemodynamic Changes Are Impaired in Muscle of Zucker Obese Rats', Diabetes, 51, (12) pp. 3492-3498. ISSN 0012-1797 (2002) [Refereed Article]

DOI: 10.2337/diabetes.51.12.3492 [eCite] [Details]

Citations: Scopus - 116Web of Science - 106

Co-authors: Wheatley C; Clark ADH; Clark MG

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2001Clark ADH, Barrett EJ, Rattigan S, Wallis MG, Clark MG, 'Insulin stimulates laser Doppler signal by rat muscle in vivo, consistent with nutritive flow recruitment', Clinical Science, 100, (3) pp. 283-290. ISSN 0143-5221 (2001) [Refereed Article]

DOI: 10.1042/CS20000104 [eCite] [Details]

Citations: Scopus - 41Web of Science - 42

Co-authors: Clark ADH; Clark MG

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2001Clark ADH, Youd JM, Rattigan S, Barrett EJ, Clark MG, 'Heterogeneity of laser Doppler flowmetry in perfused muscle indicative of nutritive and non nutritive flow', American Journal of Physiology, 280, (3) pp. H1324-H1333. ISSN 0363-6135 (2001) [Refereed Article]

DOI: 10.1152/ajpheart.2001.280.3.H1324 [eCite] [Details]

Citations: Web of Science - 22

Co-authors: Clark ADH; Clark MG

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2001Coggins M, Lindner J, Rattigan S, Jahn L, Fasy E, et al., 'Physiologic Hyperinsulinemia Enhances Human Skeletal Muscle Perfusion by Capillary Recruitment', Diabetes, 50, (12) pp. 2682-2690. ISSN 0012-1797 (2001) [Refereed Article]

DOI: 10.2337/diabetes.50.12.2682 [eCite] [Details]

Citations: Scopus - 181Web of Science - 172

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2001Keske MAV, Rattigan S, Clark MG, 'Size-Dependent Effects of Microspheres on Vasoconstrictor-Mediated Change in Oxygen Uptake by Perfused Rat Hindlimb', Microvascular Research, 62, (3) pp. 306-314. ISSN 0026-2862 (2001) [Refereed Article]

DOI: 10.1006/mvre.2001.2344 [eCite] [Details]

Citations: Scopus - 2Web of Science - 2

Co-authors: Keske MAV; Clark MG

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2001Keske MAV, Rattigan S, Clark MG, Bernard SL, Glenny RW, 'Spatial Distribution of Nutritive and Nonnutritive Vascular Routes in Perfused Rat Hindlimb Muscle Using Microspheres', Microvascular Research, 61, (1) pp. 111-121. ISSN 0026-2862 (2001) [Refereed Article]

DOI: 10.1006/mvre.2000.2278 [eCite] [Details]

Citations: Scopus - 4Web of Science - 3

Co-authors: Keske MAV; Clark MG

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2001Newman JMB, DiMaria CA, Rattigan S, Clark MG, 'Nutritive blood flow affects microdialysis O/I ratio for [14C]ethanol and 3H2O in perfused rat hindlimb', American Journal of Physiology-Heart and Circulatory Physiology, 281, (6) pp. H2731-H2737. ISSN 0363-6135 (2001) [Refereed Article]

DOI: 10.1152/ajpheart.2001.281.6.H2731 [eCite] [Details]

Citations: Web of Science - 23

Co-authors: Newman JMB; Clark MG

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2001Rattigan S, Wallis MG, Youd JM, Clark MG, 'Exercise Training Improves Insulin-Mediated Capillary Recruitment in Association With Glucose Uptake in Rat Hindlimb', Diabetes, 50, (12) pp. 2659-2665. ISSN 0012-1797 (2001) [Refereed Article]

DOI: 10.2337/diabetes.50.12.2659 [eCite] [Details]

Citations: Scopus - 41Web of Science - 44

Co-authors: Clark MG

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2000Clark MG, Clark ADH, Rattigan S, 'Failure of laser Doppler signal to correlate with total flow in muscle: Is this a question of vessel architecture?', Microvascular Research, 60, (3) pp. 294-301. ISSN 0026-2862 (2000) [Refereed Article]

DOI: 10.1006/mvre.2000.2273 [eCite] [Details]

Citations: Scopus - 11Web of Science - 9

Co-authors: Clark MG; Clark ADH

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2000Clark MG, Clerk LH, Newman JMB, Rattigan S, 'Interaction between metabolism and flow in tendon and muscle', Scandinavian Journal of Medicine and Science in Sports, 10, (6) pp. 338-345. ISSN 0905-7188 (2000) [Refereed Article]

DOI: 10.1034/j.1600-0838.2000.010006338.x [eCite] [Details]

Citations: Scopus - 9Web of Science - 9

Co-authors: Clark MG; Newman JMB

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2000Clark MG, Rattigan S, Clerk LH, Keske MAV, Clark AD, et al., 'Nutritive and non-nutritive blood flow: rest and exercise', Acta Physiologica Scandinavica, 168, (4) pp. 519-530. ISSN 0001-6772 (2000) [Refereed Article]

DOI: 10.1046/j.1365-201X.2000.00704.x [eCite] [Details]

Citations: Scopus - 61Web of Science - 56

Co-authors: Clark MG; Keske MAV; Clark AD; Newman JMB

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2000Clerk LH, Smith ME, Rattigan S, Clark MG, 'Increased chylomicron triglyceride hydrolysis by connective tissue flow in perfused rat hindlimb: Implications for lipid storage', Journal of Lipid research, 41, (3) pp. 329-335. ISSN 0022-2275 (2000) [Refereed Article]

PMID: 10706580 [eCite] [Details]

Citations: Scopus - 19Web of Science - 16

Co-authors: Smith ME; Clark MG

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2000Newman JMB, DiMaria CA, Rattigan S, Steen JT, Miller KAL, et al., 'Relationship of MTT reduction to stimulants of muscle metabolism', Chemico-Biological Interactions, 128, (2) pp. 127-140. ISSN 0009-2797 (2000) [Refereed Article]

DOI: 10.1016/S0009-2797(00)00192-7 [eCite] [Details]

Citations: Scopus - 6Web of Science - 5

Co-authors: Newman JMB; Steen JT; Miller KAL; Eldershaw TPD; Clark MG

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2000Youd JM, Rattigan S, Clark MG, 'Acute impairment of insulin-mediated capillary recruitment and glucose uptake in rat skeletal muscle in vivo by TNF-alpha', Diabetes, 49, (11) pp. 1904-1909. ISSN 0012-1797 (2000) [Refereed Article]

DOI: 10.2337/diabetes.49.11.1904 [eCite] [Details]

Citations: Scopus - 147Web of Science - 130

Co-authors: Clark MG

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1999Rattigan S, Clark MG, Barrett EJ, 'Acute vasoconstriction-induced insulin resistance in rat muscle in vivo', Diabetes, 48, (3) pp. 564-569. ISSN 0012-1797 (1999) [Refereed Article]

DOI: 10.2337/diabetes.48.3.564 [eCite] [Details]

Citations: Scopus - 98Web of Science - 93

Co-authors: Clark MG

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1999Tong CYA, DiMaria CA, Rattigan S, Clark MG, 'Na+ channel and Na+/K+ ATPase involvement in norepinephrine- and veratridine-stimulated metabolism in perfused rat hind limb', Canadian Journal of Physiology and Pharmacology, 77, (5) pp. 350-357. ISSN 0008-4212 (1999) [Refereed Article]

DOI: 10.1139/cjpp-77-5-350 [eCite] [Details]

Citations: Scopus - 11Web of Science - 10

Co-authors: Clark MG

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1999Youd JM, Newman JMB, Clark MG, Appleby GJ, Rattigan S, et al., 'Increased metabolism of infused 1-methylxanthine by working muscle', Acta Physiologica Scandinavica, 166, (4) pp. 301-308. ISSN 0001-6772 (1999) [Refereed Article]

DOI: 10.1046/j.1365-201x.1999.00572.x [eCite] [Details]

Citations: Scopus - 13Web of Science - 16

Co-authors: Newman JMB; Clark MG; Appleby GJ; Keske MAV

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1998Clark MG, Rattigan S, Newman JMB, Eldershaw TPD, 'Vascular control of nutrient delivery by flow distribution within muscle: implications for exercise and post-exercise muscle metabolism', International Journal of Sports Medicine, 19, (6) pp. 391-400. ISSN 0172-4622 (1998) [Refereed Article]

DOI: 10.1055/s-2007-971935 [eCite] [Details]

Citations: Scopus - 19Web of Science - 20

Co-authors: Clark MG; Newman JMB; Eldershaw TPD

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1998Keske MAV, Rattigan S, Clark MG, 'Microsphere infusion reverses vasoconstrictor-mediated changes in hindlimb oxygen uptake and energy status', Acta Physiologica Scandinavica, 164, (1) pp. 61-70. ISSN 0001-6772 (1998) [Refereed Article]

DOI: 10.1046/j.1365-201X.1998.00408.x [eCite] [Details]

Citations: Scopus - 10Web of Science - 10

Co-authors: Keske MAV; Clark MG

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1998Tong CYA, Rattigan S, Clark MG, 'Similarities between vasoconstrictor- and veratridine-stimulated metabolism in perfused rat hind limb', Canadian Journal of Physiology and Pharmacology, 76, (2) pp. 125-132. ISSN 0008-4212 (1998) [Refereed Article]

DOI: 10.1139/y97-179 [eCite] [Details]

Citations: Scopus - 5Web of Science - 5

Co-authors: Clark MG

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1997Rattigan S, Appleby GJ, Miller KAL, Steen JT, Dora KA, et al., 'Serotonin inhibition of 1-methylxanthine metabolism parallels its vasoconstrictor activity and inhibition of oxygen uptake in perfused rat hindlimb', Acta Physiologica Scandinavica, 161, (2) pp. 161-169. ISSN 0001-6772 (1997) [Refereed Article]

DOI: 10.1046/j.1365-201X.1997.00215.x [eCite] [Details]

Citations: Scopus - 33Web of Science - 35

Co-authors: Appleby GJ; Miller KAL; Steen JT; Dora KA; Colquhoun EQ; Clark MG

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1997Rattigan S, Clark MG, Barrett EJ, 'Hemodynamic actions of insulin in rat skeletal muscle: evidence of capillary recruitment', Diabetes, 46, (9) pp. 1381-1388. ISSN 0012-1797 (1997) [Refereed Article]

DOI: 10.2337/diabetes.46.9.1381 [eCite] [Details]

Citations: Scopus - 205Web of Science - 203

Co-authors: Clark MG

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1997Tong CYA, Rattigan S, Dora KA, Clark MG, 'Vasoconstrictor-mediated increase in muscle resting thermogenesis is inhibited by membrane-stabilizing agents', Canadian Journal of Physiology and Pharmacology, 75, (7) pp. 763-771. ISSN 0008-4212 (1997) [Refereed Article]

DOI: 10.1139/cjpp-75-7-763 [eCite] [Details]

Citations: Scopus - 10Web of Science - 10

Co-authors: Clark MG

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1996Newman JMB, Dora KA, Rattigan S, Edwards SJ, Colquhoun EQ, et al., 'Norepinephrine and serotonin vasoconstriction in rat hindlimb control different vascular flow routes', American Journal of Physiology, 270, (4) pp. E689-E699. ISSN 0193-1849 (1996) [Refereed Article]

DOI: 10.1152/ajpendo.1996.270.4.E689 [eCite] [Details]

Citations: Web of Science - 47

Co-authors: Newman JMB; Dora KA; Edwards SJ; Colquhoun EQ; Clark MG

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1996Rattigan S, Dora KA, Tong CYA, Clark MG, 'Perfused skeletal muscle contraction and metabolism improved by angiotensin II-mediated vasoconstriction', American Journal of Physiology, 271, (1) pp. E96-E103. ISSN 0193-1849 (1996) [Refereed Article]

DOI: 10.1152/ajpendo.1996.271.1.E96 [eCite] [Details]

Citations: Web of Science - 36

Co-authors: Dora KA; Clark MG

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1995Clark MG, Colquhoun EQ, Rattigan S, Dora KA, Eldershaw TPD, et al., 'Vascular and endocrine control of muscle metabolism', American Journal of Physiology: Endocrinology and Metabolism, 268, (5) pp. E797-E812. ISSN 0193-1849 (1995) [Refereed Article]

DOI: 10.1152/ajpendo.1995.268.5.E797 [eCite] [Details]

Citations: Web of Science - 152

Co-authors: Clark MG; Colquhoun EQ; Dora KA; Eldershaw TPD; Hall JL; Ye JM

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1995Eldershaw TPD, Rattigan S, Cawthorne MA, Buckingham RE, Colquhoun EQ, et al., 'Treatment with the thiazolidinedione (BRL 49653) decreases insulin resistance in obese Zucker hindlimb', Hormone and Metabolic Research, 27, (4) pp. 169-172. ISSN 0018-5043 (1995) [Refereed Article]

DOI: 10.1055/s-2007-979932 [eCite] [Details]

Citations: Scopus - 28Web of Science - 29

Co-authors: Eldershaw TPD; Colquhoun EQ; Clark MG

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1995Rattigan S, Dora KA, Colquhoun EQ, Clark MG, 'Inhibition of insulin-mediated glucose uptake in rat hindlimb by an alpha-adrenergic vascular effect', American Journal of Physiology: Endocrinology and Metabolism, 268, (2) pp. E305-E311. ISSN 0193-1849 (1995) [Refereed Article]

DOI: 10.1152/ajpendo.1995.268.2.E305 [eCite] [Details]

Citations: Web of Science - 29

Co-authors: Dora KA; Colquhoun EQ; Clark MG

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1995Ye JM, Edwards SJ, Rose RW, Rattigan S, Clark MG, et al., 'Vasoconstrictors alter oxygen, lactate, and glycerol metabolism in the perfused rat hindlimb of a rat kangaroo', American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 268, (5) pp. R1217-R1223. ISSN 0363-6119 (1995) [Refereed Article]

DOI: 10.1152/ajpregu.1995.268.5.R1217 [eCite] [Details]

Citations: Web of Science - 18

Co-authors: Ye JM; Edwards SJ; Rose RW; Clark MG; Colquhoun EQ

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1994Eldershaw TPD, Rattigan S, Dora KA, Colquhoun EQ, Clark MG, et al., 'Potential defect in the vascular control of nonshivering thermogenesis in the obese Zucker rat hind limb', Canadian Journal of Physiology and Pharmacology, 72, (12) pp. 1567-1573. ISSN 0008-4212 (1994) [Refereed Article]

DOI: 10.1139/y94-225 [eCite] [Details]

Citations: Scopus - 2Web of Science - 2

Co-authors: Eldershaw TPD; Dora KA; Colquhoun EQ; Clark MG

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1989Rattigan S, Davison AG, Cleland PJ, Clark MG, 'Effect of Phorbol Esters on the Distribution and Total Activity of Protein Kinase C in the Perfused Rat Heart', International Journal of Biochemistry, 21, (12) pp. 1415-1420. ISSN 0020-711X (1989) [Refereed Article]

DOI: 10.1016/0020-711X(89)90164-X [eCite] [Details]

Citations: Scopus - 6Web of Science - 6

Co-authors: Davison AG; Clark MG

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Chapter in Book

(4 outputs)
YearCitationAltmetrics
2013Premilovac D, Ng HLH, Richards SM, Bradley EA, Dwyer RM, et al., 'Role for the Microvasculature in Glucose Uptake in Skeletal Muscle', Glucose Uptake: Regulation, Signaling Pathways and Health Implications (Endocrinology Research and Clinical Developments), Nova Science Publishers, Johnson CC and Williams DB (ed), New York, pp. 109-139. ISBN 978-1-62618-670-5 (2013) [Research Book Chapter]

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Co-authors: Premilovac D; Ng HLH; Richards SM; Bradley EA; Dwyer RM; Keske MA

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1998Clark MG, Rattigan S, Dora KA, Newman JMB, Keske MAV, 'Interaction between blood flow, metabolism and exercise', Biochemistry of Exercise X, Human Kinetics, M Hargreaves & M Thompson (ed), Champaign, pp. 35-46. ISBN 0-88011-758-3 (1998) [Research Book Chapter]

[eCite] [Details]

Co-authors: Clark MG; Dora KA; Newman JMB; Keske MAV

1997Clark MG, Rattigan S, Dora KA, Newman JMB, Steen JT, et al., 'Vascular and metabolic regulation of muscle', Physiology, Stress and Malnutrition, Lippincott-Raven, Kinney, JM & Tucker, HN (ed), Philadelphia, pp. 325-346. ISBN 0-397-58763-5 (1997) [Research Book Chapter]

[eCite] [Details]

Co-authors: Clark MG; Dora KA; Newman JMB; Steen JT; Miller KAL; Keske MAV

1988Clark MG, Rattigan S, Cleland PJ, Edwards SJ, Davison AG, 'Cardiac Ca2+ Channels and Sarcolemma Redox', Plasma Membrane Oxidoreductases in Control of Animal and Plant Growth, Plenum Publishing Corporation, FL Crane, DJ Morre, H Low (ed), New York and London, pp. 359-368. ISBN 0-306-43092-4 (1988) [Research Book Chapter]

[eCite] [Details]

Co-authors: Clark MG; Edwards SJ; Davison AG

Review

(1 outputs)
YearCitationAltmetrics
2012Au M, Rattigan S, 'Barriers to the management of Diabetes Mellitus - is there a future role for Laser Doppler Flowmetry?', The Australasian Medical Journal, 5, (12) pp. 627-632. ISSN 1836-1935 (2012) [Substantial Review]

DOI: 10.4066/AMJ.2012.1526 [eCite] [Details]

Citations: Scopus - 2

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Conference Publication

(60 outputs)
YearCitationAltmetrics
2016Hu Donghua, Russell RD, Sharman JE, Rattigan S, Jacobson GA, et al., 'Effect of blueberry tea on improving metabolic and vascular function in people with and without type 2 diabetes - A Pilot Study', Australian Diabetes Society and Australian Diabetes Educators Association Annual Scientific Meeting 2016, 24-26 August, 2016, Gold Coast, Australia (2016) [Conference Extract]

[eCite] [Details]

Co-authors: Russell RD; Sharman JE; Jacobson GA; Al-Aubaidy HAM; Richards SM; Keske MAV

2011Newman JMB, Dwyer RM, Keske MAV, Richards SM, Rattigan S, 'Flow motion in skeletal muscle is associated with increased nutritive flow and insulin action', Proceedings of the 71st Scientific Sessions of the American Diabetes Association, 24-28 June, San Diego, California, pp. 1740-P. (2011) [Conference Extract]

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Co-authors: Newman JMB; Dwyer RM; Keske MAV; Richards SM

2011Rattigan S, Newman JMB, Dwyer RM, Richards S, Keske MAV, 'Flow motion in skeletal muscle microvasculature is associated with increased nutritive flow', Australia and New Zealand Microcirculation Society Conference, 30 Nov - 3 Dec, Western Australia (2011) [Conference Extract]

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Co-authors: Newman JMB; Dwyer RM; Keske MAV

2006Bradley EA, Clark MG, Rattigan S, 'Acute AICAR infusion stimulates capillary recruitment in skeletal muscle', Diabetes, vol 55, Supplement 1, 9-13 June, 2006, Washington, pp. A336. ISSN 0012-1797 (2006) [Conference Extract]

[eCite] [Details]

Co-authors: Bradley EA; Clark MG

2006Clark MG, Dwyer RM, Newman JMB, Richards SM, Rattigan S, 'A comparison of ultrasound and laser Doppler for Measuring Capillary Recruitment Using Models in vitro', Proceedings, 27-30 September, 2006, Indianapolis, pp. 10. (2006) [Conference Extract]

[eCite] [Details]

Co-authors: Clark MG; Dwyer RM; Newman JMB; Richards SM

2006Clark MG, Vollus GC, Roberts MK, Rattigan S, 'Insulin delivery to muscle is sensitive to tissue perfusion', Diabetologia, vol 49, Supplement 1, 14-17 September, 2006, Copenhagen-Malmo, pp. 370-371. ISSN 0012-186X (2006) [Conference Extract]

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Co-authors: Clark MG; Vollus GC

2006Dwyer RM, Kolka CM, Rattigan S, Clark MG, 'Endothelin-1 inhibits insulin action in vivo', Diabetologia, vol 49, Supplement 1, 14-17 September, 2006, Copenhagen-Malmo, pp. 373. ISSN 0012-186X (2006) [Conference Extract]

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Co-authors: Dwyer RM; Clark MG

2006Dwyer RM, Newman JMB, Richards SM, Rattigan S, Clark MG, 'Laser Doppler flowmetry, but not contrast enhanced ultrasound, influenced by flow when measuring changes in muscle capillary recruitment - a study in vitro', Proceedings of Meeting, 13th September, 2006, Copenhagen, pp. 16. (2006) [Conference Extract]

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Co-authors: Dwyer RM; Newman JMB; Richards SM; Clark MG

2006Genders AJ, Rattigan S, Clark MG, Richards SM, 'cGMP degrading phosphodiesterases are expressed differentially in skeletal muscle vasculature', Diabetes, vol 55, Supplement 1, 9-13 June, 2006, Washington, pp. A333. ISSN 0012-1797 (2006) [Conference Extract]

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Co-authors: Genders AJ; Clark MG; Richards SM

2006Genders AJ, Rattigan S, Clark MG, Richards SM, 'Differential expression of cGMP degrading phosphodiesterases in skeletal muscle vasculature', Proceedings, 24-28 September, 2006, Brisbane, pp. 130. ISSN 1328-4924 (2006) [Conference Extract]

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Co-authors: Genders AJ; Clark MG; Richards SM

2006Newman JMB, Clark MG, Dwyer RM, Richards SM, Rattigan S, 'Use of microdialysis to assess capillary recruitment in muscle - a study in vitro', Proceedings of Meeting, 13th September, 2006, Copenhagen, pp. 17. (2006) [Conference Extract]

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Co-authors: Newman JMB; Clark MG; Dwyer RM; Richards SM

2005Carins R, Rattigan S, Clark MG, 'Resiniferatoxin treatment reverses impaired capillary recruitment and insulin resistance in the obese Zucker rat', Diabetes, Vol 54, Supplement 1, June 10-14, 2005, San Diego, pp. A16. ISSN 0012-1797 (2005) [Conference Extract]

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Co-authors: Clark MG

2005Clark MG, Wallis MG, Smith ME, Kolka CM, Zhang L, et al., 'Glucosamine induces acute insulin resistance in muscle in vivo assocaited with impaired capillary recruitment', Diabetologia, 48 (S1), 10-15 September, 2005, Athens, pp. A210. ISSN 0012-186X (2005) [Conference Extract]

[eCite] [Details]

Co-authors: Clark MG; Smith ME; Kolka CM; Zhang L; Richards SM

2005Kolka CM, Rattigan S, Richards SM, Clark MG, 'Endothelin-1 vascular and resultant metabolic actions in perfused rat hindlimb are opposed by insulin', Diabetologia, vol 48, Supplement 1, 10-15 September, 2005, Athens, pp. A230. ISSN 0012-186X (2005) [Conference Extract]

[eCite] [Details]

Co-authors: Kolka CM; Richards SM; Clark MG

2005Mahajan H, Richards SM, Rattigan S, Clark MG, 'Local infusion of an inhibitor of Ca2+ dependent K+ channels (TEA), but not L-NAME blocks insulin-mediated capillary recruitment and glucose uptake in muscle in vivo', Diabetes, Vol 54, Supplement 1, June 10-14, 2005, San Diego, pp. A379. ISSN 0012-1797 (2005) [Conference Extract]

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Co-authors: Mahajan H; Richards SM; Clark MG

2005Vollus GC, Newman JMB, Richards SM, Barrett EJ, Rattigan S, 'Partial microsphere embolism of muscle leads to acute impairment of insulin-mediated glucose uptake without compromising resting energetics', Diabetes, Vol 54, Supplement 1, June 10-14, 2005, San Diego, pp. A379. ISSN 0012-1797 (2005) [Conference Extract]

[eCite] [Details]

Co-authors: Vollus GC; Newman JMB; Richards SM

2004Kolka CM, Rattigan S, Richards SM, Clark MG, 'Endothelin-1 as a messenger for insulin has both stimulatory and inhibitory effects on perfused muscle metabolism via its vascular actions', Diabetes, Vol 53, Supplement 2, June 4-8, 2004, Orlando, pp. A368. ISSN 0012-1797 (2004) [Conference Extract]

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Co-authors: Kolka CM; Richards SM; Clark MG

2004Mahajan H, Richards SM, Rattigan S, Clark MG, 'Local methacholine but not bradykinin potentiates insulin-mediated capillary recruitment and glucose uptake in muscle in vivo', Diabetes, Vol 53, Supplement 2, June 4-8, 2004, Orlando, pp. A369. ISSN 0012-1797 (2004) [Conference Extract]

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Co-authors: Mahajan H; Richards SM; Clark MG

2004Steinberg GR, Dwyer RM, Carey AL, Rogers S, Richards SM, et al., 'Interleukin-6 increases glucose uptake but does not increase AMPK activity in L6 myotubes and perfused rat hindlimb', Proceedings of AMPK Meeting, 23-26 March, 2004, Lorne, pp. 126. (2004) [Conference Extract]

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Co-authors: Dwyer RM; Richards SM; Clark MG

2004Wheatley CM, Barrett EJ, Bradley EA, Richards SM, Clark MG, et al., 'Muscle capillary recruitment and glucose uptake of genetically obese rats respond to contractions but not insulin', Diabetes, Vol 53, Supplement 2, June 4-8, 2004, Orlando, pp. A371. ISSN 0012-1797 (2004) [Conference Extract]

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Co-authors: Bradley EA; Richards SM; Clark MG

2004Wheatley CM, Richards SM, Clark MG, Barrett EJ, Rattigan S, 'Role of capillary recruitment in the potentiation of insulin action by prior exercise', Diabetes, Vol 53, Supplement 2, June 4-8, 2004, Orlando, pp. A28. ISSN 0012-1797 (2004) [Conference Extract]

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Co-authors: Richards SM; Clark MG

2003Bradley EA, Zhang L, Newman JMB, Richards SM, Clark MG, et al., 'Acute divergent effects of AICAR on insulin action in vivo', Diabetes, Vol 52, Supplement 1, June 13-17, 2003, New Orleans, pp. A344. ISSN 0012-1797 (2003) [Conference Extract]

[eCite] [Details]

Co-authors: Bradley EA; Zhang L; Newman JMB; Richards SM; Clark MG

2003Clark MG, Zhang L, Wheatley CM, Febbraio MA, Rattigan S, 'TNFα and IL-6 differently affect insulin action in vivo', Diabetologia, Vol 46, Supplement 2, 24-29 August, 2003, Paris, pp. A58. ISSN 0012-186X (2003) [Conference Extract]

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Co-authors: Clark MG; Zhang L

2003Mahajan H, Richards SM, Rattigan S, Clark MG, 'T-1032 a cyclic GMP phosphodiesterase-5 inhibitor blocks physiologic insulin-mediated muscle hemodynamic effects and glucose uptake in vivo', Diabetes, Vol 52, Supplement 1, June 13-17, 2003, New Orleans, pp. A541. ISSN 0012-1797 (2003) [Conference Extract]

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Co-authors: Mahajan H; Richards SM; Clark MG

2003Rattigan S, Bradley EA, Clark MG, 'Effects of wortmannin on insulin-mediated action in vivo', Diabetes, Vol 52, Supplement 1, June 13-17, 2003, New Orleans, pp. A543. ISSN 0012-1797 (2003) [Conference Extract]

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Co-authors: Bradley EA; Clark MG

2003Richards SM, Wheatley CM, Zhang L, Rattigan S, Barrett EJ, et al., 'Contraction-mediated muscle capillary recruitment and metabolic responses in vivo are resistant to TNFα', Diabetologia, Vol 46, Supplement 2, 24-29 August, 2003, Paris, pp. A58. ISSN 0012-186X (2003) [Conference Extract]

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Co-authors: Richards SM; Zhang L; Clark MG

2003Zhang L, Richards SM, Rattigan S, Barrett EJ, Clark MG, 'Capillary recruitment in muscle is a highly sensitive event in insulin action in vivo', Diabetes, Vol 52, Supplement 1, June 13-17, 2003, New Orleans, pp. A48. ISSN 0012-1797 (2003) [Conference Extract]

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Co-authors: Zhang L; Richards SM; Clark MG

2002Clerk LH, Smith ME, Rattigan S, Clark MG, 'Reduced nutritive flow in experimental hypertension: the cause of hyperglycemia and hyperlipidemia?', Diabetes, Vol 51, Supplement 2, June 14-18, 2002, San Francisco, pp. A335. ISSN 0012-1797 (2002) [Conference Extract]

[eCite] [Details]

Co-authors: Smith ME; Clark MG

2002Wheatley CM, Bradley EA, Wallis MG, Rattigan S, Richards SM, et al., 'Contraction-mediated capillary recruitment is not impaired in muscle of insulin-resistant obese Zucker rats', Diabetes, Vol 51, Supplement 2, June 14-18, 2002, San Francisco, pp. A564. ISSN 0012-1797 (2002) [Conference Extract]

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Co-authors: Bradley EA; Richards SM; Clark MG

2002Zhang L, Rattigan S, Richards SM, Clark MG, 'TNF? inhibits low physiologic but not high insulin-mediated capillary recruitment and glucose uptake in vivo', Diabetes, Vol 51, Supplement 2, June 14-18, 2002, San Francisco, pp. A565. ISSN 0012-1797 (2002) [Conference Extract]

[eCite] [Details]

Co-authors: Zhang L; Richards SM; Clark MG

2001Clark ADH, Wallis MG, Rattigan S, Barrett EJ, Clark MG, 'Insulin-mediated capillary recruitment is impaired in muscle of obese Zucker rats', Diabetes, Vol 50, Supplement 2, June 22-26, 2001, Philadelphia, pp. A329. ISSN 0012-1797 (2001) [Conference Extract]

[eCite] [Details]

Co-authors: Clark ADH; Clark MG

2001Clark MG, Barrett EJ, Richards SM, Clark ADH, Rattigan S, 'Microvascular involvement in insulin resistance of skeletal muscle', Proceedings of the 7th World Congress for Microcirculation, August 19-22, 2001, Sydney, pp. 31-37. (2001) [Non Refereed Conference Paper]

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Co-authors: Clark MG; Richards SM; Clark ADH

2001Clark MG, Rattigan S, 'Microvascular involvement in insulin resistance of skeletal muscle', Proceedings of the 7th World Congress for Microcirculation, 19-22 August, 2001, Sydney, pp. Sym 16-3. (2001) [Conference Extract]

[eCite] [Details]

Co-authors: Clark MG

2001Clark MG, Rattigan S, 'Insulin-mediated capillary recruitment in muscle: implications for glucose uptake and insulin resistance', Proceedings of the Australian Physiological and Pharmacolical Society, 2-3 September, 2001, Melbourne, pp. 9P. ISSN 0067-2084 (2001) [Conference Extract]

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Co-authors: Clark MG

2001Keske MAV, Rattigan S, Clark MG, Barrett EJ, 'Inhibition of nitric oxide synthase prevents insulin-stimulated capillary recruitment and glucose uptake in skeletal muscle in vivo', Diabetes, vol 50, Supplement 2, June 22-26, 2001, Philadelphia, pp. A334. ISSN 0012-1797 (2001) [Conference Extract]

[eCite] [Details]

Co-authors: Keske MAV; Clark MG

2001Newman JMB, DiMaria CA, Rattigan S, Clark MG, 'Nutritive and non-nutritive blood flow in muscle affects microdialysis outflow/inflow ratio', Proceedings of the 7th World Congress for Microcirculation, 19-22 August, 2001, Sydney, pp. Pos 2-30. (2001) [Conference Extract]

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Co-authors: Newman JMB; Clark MG

2001Rattigan S, 'Insulin Action in Skeletal Muscle and Skin Microcirculation', Proceedings of the 7th World Congress for Microcirculation, 19-22 August, 2001, Sydney, pp. Sym 16. (2001) [Chair International Conference]

[eCite] [Details]

2001Rattigan S, Wallis MG, Youd JM, Clark MG, 'Insulin-mediated capillary recruitment and glucose uptake in rat hindlimb enhanced by voluntary exercise training', Diabetes, Vol 50, Supplement 2, June 22-26, 2001, Philadelphia, pp. A225. ISSN 0012-1797 (2001) [Conference Extract]

[eCite] [Details]

Co-authors: Clark MG

2001Rattigan S, Wallis MG, Youd JM, Clark MG, 'Exercise training by rats enhances insulin's microvascular effects in skeletal muscle', Proceedings of the 7th World Congress for Microcirculation, 19-22 August, 2001, Sydney, pp. Pos 1-49. (2001) [Conference Extract]

[eCite] [Details]

Co-authors: Clark MG

2000Clark MG, Youd JM, Newman JMB, Rattigan S, 'Sciatic nerve severance produces insulin resistance without changes in 1-MX metabolism', Diabetes, vol 49, Supplement 1, 9-13 June, 2000, San Antonio, TX, USA, pp. 1736-PO. ISSN 0012-1797 (2000) [Conference Extract]

[eCite] [Details]

Co-authors: Clark MG; Newman JMB

2000Clerk LH, Smith ME, Rattigan S, Clark MG, 'Haemodynamic insulin resistance increases fatty acid uptake by connective tissue adipocytes in red muscles', Diabetologia, vol 43, Supplement 1, 17-21 September, 2000, Jerusalem, Israel, pp. A163. ISSN 0012-186X (2000) [Conference Extract]

[eCite] [Details]

Co-authors: Smith ME; Clark MG

1999DiMaria CA, Tong CYA, Rattigan S, Clark MG, 'Thermogenesis in resting muscle: a role for sodium channels?', Proceedings of the Australian Society for Biochemistry and Molecular Biology, 27-30 September 1999, Gold Coast, pp. Sym-10-02. (1999) [Conference Extract]

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Co-authors: Clark MG

1999Rattigan S, Clark MG, 'Oxygen uptake stimulated by veratridine but not phenylephrine in the constant-flow arrested rat heart: absence of vasoconstrictor-mediated thermogenesis in heart', Proceedings of the Australian Society for Biochemistry and Molecular Biology, 27-30 September 1999, Gold Coast, pp. Pos-Mon-38. (1999) [Conference Extract]

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Co-authors: Clark MG

1998Clerk LH, Smith ME, Rattigan S, Clark MG, 'Circulating triglyceride and muscle', Proceedings of the Australasian Society for the Study of Obesity, 24-25 October, 1998, Gold Coast, Qld, pp. 26. (1998) [Conference Extract]

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Co-authors: Smith ME; Clark MG

1998DiMaria CA, Tong CYA, Rattigan S, Clark MG, 'Thermogenesis of resting muscle: key roles for sodium channels and Na+/K+ ATPase in catecholamine effects', Proceedings of the Australian Society for Biochemistry and Molecular Biology, 28 September - 1 October, 1998, Adelaide, pp. Pos-Mon-193. (1998) [Conference Extract]

[eCite] [Details]

Co-authors: Clark MG

1998Rattigan S, Barrett EJ, Clark MG, 'Vascular induced insulin resistance', Proceedings of the Australian Diabetes Society and Australian Diabetes Educators Association, 26-28 August, 1998, Perth, pp. 127. ISBN 1-875690-23-9 (1998) [Conference Extract]

[eCite] [Details]

Co-authors: Clark MG

1998Rattigan S, Youd JM, Clark MG, 'Insulin action and blood flow within muscle', Proceedings of the Australian Society for Medical Research, 22-25 November 1998, Hobart, pp. S7.4. (1998) [Conference Extract]

[eCite] [Details]

Co-authors: Clark MG

1998Youd JM, Rattigan S, Clark ADH, Clark MG, 'Blood flow and glucose uptake by muscle', Proceedings of the Australian Society for Biochemistry and Molecular Biology, 28 September - 1 October, Adelaide, pp. Sym-32-06. (1998) [Conference Extract]

[eCite] [Details]

Co-authors: Clark ADH; Clark MG

1997Clark MG, Rattigan S, Barrett EJ, 'Regulation of muscle glucose uptake in vivo by insulin-mediated capillary recruitment', Proceedings of the Australian Society for Biochemistry and Molecular Biology, Melbourne, pp. Sym B5-2. (1997) [Conference Extract]

[eCite] [Details]

Co-authors: Clark MG

1997Newman JMB, Clark MG, Rattigan S, Appleby GJ, Keske MAV, et al., 'Effect of Muscle Contraction on Metabolism of 1-Methylxanthine and L-Arginine in the Constant-Flow Perfused Rat Hindlimb', 10th International Conference on the Biochemistry of Exercise, Sydney, pp. 76. (1997) [Conference Extract]

[eCite] [Details]

Co-authors: Newman JMB; Clark MG; Appleby GJ; Keske MAV

1997Rattigan S, Barrett EJ, Appleby GJ, Clark MG, '1-Methylxanthine Metabolism in Rat Skeletal Muscle Indicative of Nutritive Blood flow in Vitro and in Vivo', 10th International Biochemistry of Exercise Conference, Sydney, pp. 76. (1997) [Conference Extract]

[eCite] [Details]

Co-authors: Appleby GJ; Clark MG

1997Rattigan S, Barrett EJ, Clark MG, 'Evidence of Capillary Recruitment by Insulin but not Epinephrine in Rat Muscle in Vivo', Diabetes, New Orleans, USA, pp. 84A. (1997) [Conference Extract]

[eCite] [Details]

Co-authors: Clark MG

1997Rattigan S, Barrett EJ, Clark MG, 'Hemodynamic Effects of Insulin Action in Rat Skeletal Muscle in Vivo', FASEB Journal, Los Angeles, pp. A506. (1997) [Conference Extract]

[eCite] [Details]

Co-authors: Clark MG

1997Youd JM, Rattigan S, Keske MAV, Clark MG, 'Sciatic Nerve Severance Produces Haemodynamic Changes and Insulin Resistance in Muscle', Diabetologia, Helsinki, pp. A257. (1997) [Conference Extract]

[eCite] [Details]

Co-authors: Keske MAV; Clark MG

1996Clark MG, Rattigan S, Barrett EJ, 'Vasoconstrictor-mediated blood flow redistribution and acute insulin resistance in rat skeletal muscle in vivo', European Association for the Study of Diabetes, Vienna, Austria, pp. A175. (1996) [Conference Extract]

[eCite] [Details]

Co-authors: Clark MG

1996Rattigan S, Barrett EJ, Clark MG, 'Insulin alters the distribution of volume of blood flow in rat skeletal muscle in vivo: Assessment by 1-methylxanthine metabolism and ultrasound', American Diabetes Association Meeting, San Francisco, CA USA, pp. 307A. (1996) [Conference Extract]

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Co-authors: Clark MG

1996Rattigan S, Barrett EJ, Clark MG, 'Skeletal muscle vascular involvement in insulin action and insulin resistance', International Symposium on Resistance Arteries 1996, Cambridge, UK, pp. 25. (1996) [Conference Extract]

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Co-authors: Clark MG

1995Eldershaw TPD, Colquhoun EQ, Dora KA, Rattigan S, Clark MG, 'Increased resting muscle thermogenesis using pharmacological intervention', Fourth Scientific Meeting of the Australian Society for the Study of Obesity, Melbourne, Vic., pp. 41. (1995) [Conference Extract]

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Co-authors: Eldershaw TPD; Colquhoun EQ; Dora KA; Clark MG

1995Matthias A, Miller KAL, Newman JMB, Steen JT, Rattigan S, et al., 'Fatty acids as potential mediators of skeletal muscle thermogenesis', 1st Colloquium on Mitochondria and Myopathies, Halle/Saale, pp. B60. (1995) [Conference Extract]

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Co-authors: Miller KAL; Newman JMB; Steen JT; Dora KA; Colquhoun EQ; Clark MG

1995Ye JM, Dora KA, Rattigan S, Clark MG, Colquhoun EQ, 'Stimulation of oxygen uptake (VO2) in muscle by alpha1- and beta3-adrenoceptors', Fourth Scientific Meeting of the Australian Society for the Study of Obesity, Melbourne, Vic., pp. 40. (1995) [Conference Extract]

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Co-authors: Ye JM; Dora KA; Clark MG; Colquhoun EQ

Patent

(4 outputs)
YearCitationAltmetrics
2001Clark MG, Rattigan S, 'Methods and pharmaceuticals for treating muscle insulin resistance and related conditions' (2001) [Patent Application]

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Co-authors: Clark MG

2001Clark MG, Rattigan S, 'Methods and pharmaceuticals for treating muscle insulin resistance and related conditions' (2001) [Patent]

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Co-authors: Clark MG

2001Clark MG, Rattigan S, Barret EJ, Lindner J, Kaul S, 'Improved method of measuring changes in microvascular capillary blood flow' (2001) [Patent]

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Co-authors: Clark MG

2001Clark MG, Rattigan S, Barrett EJ, Lindner JR, Kaul S, 'Improved method of measuring changes in microvascular capillary blood flow' (2001) [Patent Application]

[eCite] [Details]

Co-authors: Clark MG

Grants & Funding

In the last 5 years Prof Rattigan has obtained competitive research funding from ARC, NHMRC, National Institutes of Health USA, Diabetes Australia, National Heart Foundation and other granting bodies totalling over $2.2 million.

Funding Summary

Number of grants

46

Total funding

$8,866,219

Projects

Mixed Meal Challenge A new diagnostic test for screening pre diabetes (2016)$24,225
Description
The oral glucose tolerance test (GTT) is the gold standard for assessing pre-diabetes and type 2 diabetes (T2D), and is used world-wide. However, our researchgroup has made an important discovery demonstrating the GTT causes acute microvascular insulin resistance in healthy people. These findings have asignificant clinical impact as it implies that the GTT does not have the sensitivity to identify people with vascular-derived insulin resistance which is one of theearliest events in the development of pre-diabetes. Therefore, people with vascular‐derived insulin resistance are not being identified or diagnosed. We have developed an alternative test (the mixed meal challenge; MMC) and hypothesise it will have greater capacity to screen for pre-diabetes.Aim 1: Determine whether the MMC can identify pre-diabetes in a population of people that would otherwise be considered healthy in response to a GTT.Aim 2: Determine whether the benefits of the MMC as a new diagnostic test is linked to microvascular insulin sensitivity in skeletal muscle.
Funding
Royal Hobart Hospital Research Foundation ($24,225)
Scheme
Grant-Establishment
Administered By
University of Tasmania
Research Team
Keske MAV; Greenaway TM; Rattigan S; Russell RD; Neilson S
Year
2016
Microvascular dysfunction in adult offspring of type 2 diabetics (2014)$20,294
Description
Offspring from type 2 diabetics (T2D) are at much greater risk of developing diabetes than a person with no family history. The mechanism for this increase in risk is not known. This project will determine whether microvascular dysfunction in skeletal muscle and skin of first degree relatives with T2D occurs before development of insulin resistance. We will recruit people with and without family history of T2D. It will measure microvascular actions (using ultrasound) in these people before and after a mixed meal challenge. The outcomes of this study will determine whether monitoring microvasculature responses in muscle is an important 'early' strategy for assessing risk that might inform patient treatment to prevent or delay progression to insulin resistance or T2D.
Funding
Royal Hobart Hospital Research Foundation ($20,294)
Scheme
Grant-Clinical Research
Administered By
University of Tasmania
Research Team
Keske MAV; Rattigan S; Sharman JE; Russell R; Premilovac D
Year
2014
Cardiometabolic benefits of exercise training in type 2 diabetes independent of weight loss (2014)$50,735
Description
This project will recruit an overweight type 2 diabetes cohort, medically assessed for an exercise program. It aims to recruit some with family history of type 2 diabetes and some without. The cohort with exercise test before and after 6 weeks of the exercise program, with type 2 medications discontinued before test. The aim is to show that heart health will not be as good with family history of type 2 and that exercise will improve heart health but will be of more benefit to those with a family history than those without.
Funding
University of Tasmania ($50,735)
Scheme
vTAHSP Demonstration Projects
Administered By
University of Tasmania
Research Team
Keske MAV; Greenaway T; Marwick TH; Ross RM; Rattigan S; Sharman JE; Premilovac D
Year
2014
Role of microvascular flowmotion in skeletal muscle glucose metabolism (2013 - 2015)$576,533
Description
Obesity and type 2 diabetes are nationally and globally reaching epidemic rates. This project investigates the regulation of blood flow within muscle and its impact on metabolism. Outcomes from the study may lead to diagnostic tools and treatments for cardiovascular disease associated with obesity, hypertension and type 2 diabetes.
Funding
National Health & Medical Research Council ($576,533)
Scheme
Grant-Project
Administered By
University of Tasmania
Research Team
Rattigan S; Keske MAV; Richards SM; Ross RM
Period
2013 - 2015
Grant Reference
1043474_HF
Neural regulation of skeletal muscle insulin sensitivity (2012)$9,825
Funding
The Select Foundation ($9,825)
Scheme
Grant-Small Grants Scheme
Administered By
University of Tasmania
Research Team
Rattigan S; Keske MAV; Dickson TC
Year
2012
Actions of the polyphenol epigallocatechin 3-gallate on insulin sensitivity (2011 - 2013)$395,518
Funding
National Health & Medical Research Council ($395,518)
Scheme
Grant-Project
Administered By
University of Tasmania
Research Team
Keske MAV; Rattigan S; Quon M
Period
2011 - 2013
Grant Reference
1009962
Microvascular Defects and Insulin Resistance (2011 - 2012)$127,490
Funding
National Heart Foundation ($127,490)
Scheme
Grant-In-Aid
Administered By
University of Tasmania
Research Team
Rattigan S; Keske MAV; Richards SM
Period
2011 - 2012
Near Miss - Microvascular Blood Flow in Cardiovascular Disease (2011)$12,500
Funding
University of Tasmania ($12,500)
Scheme
Grant-Near Misses
Administered By
University of Tasmania
Research Team
Rattigan S
Year
2011
Does exercise increase skeletal muscle insulin sensitivity via nitric oxide? (2011 - 2013)$543,390
Funding
National Health & Medical Research Council ($543,390)
Scheme
Grant-Project
Administered By
Victoria University
Research Team
McConnell G; Rattigan S
Period
2011 - 2013
Grant Reference
1012181
Ambulatory central blood pressure as a novel explanation for diabetes-associated brain damage (2011)$55,597
Funding
Diabetes Australia Research Trust ($55,597)
Scheme
Grant-Research [1 year]
Administered By
University of Tasmania
Research Team
Sharman JE; Rattigan S; Srikanth V
Year
2011
Steve Rattigan_Discretionary Account (2008 - 2009)$20,000
Funding
Menzies Institute for Medical Research ($20,000)
Scheme
Consultancy
Administered By
University of Tasmania
Research Team
Rattigan S
Period
2008 - 2009
NHMRC Standard Equipment Grant - 2008 (2008)$72,611
Funding
National Health & Medical Research Council ($72,611)
Scheme
Grant-Equipment
Administered By
University of Tasmania
Research Team
Keske MAV; Rattigan S; Richards SM
Year
2008
Grant Reference
580023
Blood Flow Routes in Muscle (2008 - 2010)$390,000
Funding
Australian Research Council ($390,000)
Scheme
Grant-Discovery Projects
Administered By
University of Tasmania
Research Team
Keske MAV; Rattigan S
Period
2008 - 2010
Grant Reference
DP0877385
NHMRC Research Fellowship (SRFA) (2008 - 2013)$655,657
Funding
National Health & Medical Research Council ($655,657)
Scheme
Fellowship-Research
Administered By
University of Tasmania
Research Team
Rattigan S
Period
2008 - 2013
Grant Reference
490034
Interaction between adiponectin and insulin in vascular control of glucose uptake in muscle (2008 - 2009)$119,574
Funding
National Heart Foundation ($119,574)
Scheme
Grant-In-Aid
Administered By
University of Tasmania
Research Team
Rattigan S; Richards SM
Period
2008 - 2009
Central and Peripheral Actions of Insulin for the Control of Muscle Capillary Recruitment (2007 - 2009)$417,750
Funding
National Health & Medical Research Council ($417,750)
Scheme
Grant-Project
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Richards SM; Choi-Lundberg DL
Period
2007 - 2009
Grant Reference
457603
Endothelin-1, type2 diabetes and hypertension (2007 - 2008)$112,680
Funding
National Heart Foundation ($112,680)
Scheme
Grant-In-Aid
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Richards SM; Kolka CM
Period
2007 - 2008
The Effects of Insulin on the Microvasculature (2006 - 2010)$347,499
Funding
National Institutes of Health ($347,499)
Scheme
Grant
Administered By
University of Virginia
Research Team
Clark MG; Rattigan S; Richards SM
Period
2006 - 2010
Isoelectric Focussing System (2006)$15,080
Funding
National Health & Medical Research Council ($15,080)
Scheme
Grant-Equipment
Administered By
University of Tasmania
Research Team
Richards SM; Rattigan S
Year
2006
Grant Reference
361670
Nutrient and Hormone Delivery to Muscle: Interactions between Insulin and Exercise (2005 - 2007)$299,500
Funding
National Health & Medical Research Council ($299,500)
Scheme
Grant-Project Three Year
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Richards SM
Period
2005 - 2007
Grant Reference
352600
Novel Therapeutic Interventions to Increase Blood Flow to Skeletal Muscle (2005 - 2007)$354,750
Funding
National Health & Medical Research Council ($354,750)
Scheme
Grant-Project
Administered By
National Health & Medical Research Council
Research Team
Febbraio M; Clark MG; Hill M; Hiscock N; Rattigan S
Period
2005 - 2007
Grant Reference
342115
Leica DMIRB Inverted Microscope Configured for Fluorescence and Bright Field with Phase Contrast (2005)$10,000
Funding
National Health & Medical Research Council ($10,000)
Scheme
Grant-Equipment
Administered By
University of Tasmania
Research Team
Chuah MI; West AK; Holloway AF; Rattigan S; Richards SM; Chung RS; Foa LC
Year
2005
Grant Reference
264668
NIDDM-GSK-Comparing Rosiglitazone and Metformnum for Microvascular Action in Muscle (2004 - 2005)$106,400
Funding
GlaxoSmithKline Australia ($106,400)
Scheme
Contract Research
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S
Period
2004 - 2005
Muscle Vascular Research and Gene Therapy Using Ultrasound (2004)$142,900
Funding
Australian Research Council ($102,900)
Collaborators
Deakin University ($10,000); Royal Melbourne Institute of Technology University ($10,000); University of Melbourne ($10,000); University of New South Wales ($10,000)
Scheme
Grant-Linkage Infrastructure
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Richards SM
Year
2004
Grant Reference
LE0452281
Refrigerated Benchtop Centrifuge (2004)$12,941
Funding
National Health & Medical Research Council ($12,941)
Scheme
Grant-Equipment
Administered By
University of Tasmania
Research Team
Holloway AF; West AK; Chuah MI; Rattigan S; Richards SM
Year
2004
Grant Reference
264536
The Role of the Endothelium in Insulin's In Vivo Action Upon Skeletal Muscle Metabolism (2004 - 2006)$444,750
Funding
National Health & Medical Research Council ($444,750)
Scheme
Grant-Project Three Year
Administered By
University of Tasmania
Research Team
Rattigan S
Period
2004 - 2006
Grant Reference
302200
Heart Foundation Career Development Fellowship (2004 - 2008)$433,000
Funding
National Heart Foundation ($433,000)
Scheme
Fellowship-Postdoctoral
Administered By
University of Tasmania
Research Team
Rattigan S
Period
2004 - 2008
Gradient Thermal Cycler for PCR (2004)$7,055
Funding
National Health & Medical Research Council ($7,055)
Scheme
Grant-Equipment
Administered By
University of Tasmania
Research Team
Richards SM; Rattigan S
Year
2004
Grant Reference
264536
Augmenting Microvascular Blood Flow in Muscle (2003 - 2005)$210,000
Funding
National Health & Medical Research Council ($210,000)
Scheme
Grant-Project Three Year
Administered By
University of Tasmania
Research Team
Clark MG; Richards SM; Rattigan S
Period
2003 - 2005
Grant Reference
253900
Relationship Between Muscle Insulin Resistance and High Blood Pressure (2003 - 2004)$90,000
Funding
National Heart Foundation ($90,000)
Scheme
Grant-In-Aid
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Richards SM
Period
2003 - 2004
Mechanisms Linking Insulin-Mediated Muscle Capillary Recruitment and Glucose Uptake (2002 - 2004)$315,000
Funding
National Health & Medical Research Council ($315,000)
Scheme
Grant-Project Three Year
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S
Period
2002 - 2004
Grant Reference
211302
The Physiological Effect of Insulin on Microvascular Flow (2001 - 2005)$686,437
Funding
National Institutes of Health ($686,437)
Scheme
Grant
Administered By
University of Virginia
Research Team
Clark MG; Rattigan S; Clark ADH
Period
2001 - 2005
Detrimental Haemodynamic Changes in Skeletal Muscle From Chronic Heart Failure (2001 - 2002)$68,400
Funding
National Heart Foundation ($68,400)
Scheme
Grant-In-Aid
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Richards SM
Period
2001 - 2002
Development of Laser Doppler Flowmetry for Assessment of Muscle Microvascular Flow in Insulin Resistance (2000)$32,200
Funding
Clifford Craig Foundation ($32,200)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Richards SM; Clark ADH
Year
2000
The Role of Nutritive and Non-nutritive Blood Flow on Lipid Clearance by Normal and Insulin-resistant Muscle (1999 - 2000)$73,514
Funding
National Heart Foundation ($73,514)
Scheme
Grant-In-Aid
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Richards SM
Period
1999 - 2000
Haemodynamic Effects of Tumour Necrosis Factor-A to cause Muscle Insulin Resistance (1999)$20,000
Funding
Diabetes Australia Research Trust ($20,000)
Scheme
Grant-Research [1 year]
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Clark ADH
Year
1999
Skeletal Muscle Capillary Recruitment and Insulin Action (1999 - 2001)$56,591
Funding
American Diabetes Association ($56,591)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S; Clark ADH
Period
1999 - 2001
Insulin resistance in muscle from haemodynamic changes (1998 - 2002)$574,676
Funding
National Health & Medical Research Council ($574,676)
Scheme
Grant-MRC:Project-Extended
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S
Period
1998 - 2002
Grant Reference
981520
A muscle haemodynamic basis for hypertriglyceridemia and insulin resistance of hypertension. (1997 - 1998)$86,000
Funding
National Heart Foundation ($86,000)
Scheme
Grant-Biomedical
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S
Period
1997 - 1998
Effects of vasomodulators on lipid clearance by perfused muscle (1996 - 1998)$183,593
Funding
National Health & Medical Research Council ($183,593)
Scheme
Grant-MRC Project
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S
Period
1996 - 1998
Grant Reference
961020
A haemodynamic basis for insulin resistance in skeletal muscle (1995 - 1997)$224,961
Funding
National Health & Medical Research Council ($224,961)
Scheme
Grant-MRC Project
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S
Period
1995 - 1997
Grant Reference
951225
Insulin resistant diabetes resulting from haemodynamic changes within muscle (1995)$100,000
Funding
Australian Mutual Provident Society ($100,000)
Scheme
Grant
Administered By
University of Tasmania
Research Team
Clark MG; Rattigan S
Year
1995
Diode array detector (1994)$10,400
Funding
National Health & Medical Research Council ($10,400)
Scheme
Grant-Equipment
Administered By
University of Tasmania
Research Team
Clark MG; Colquhoun EQ; Rattigan S
Year
1994
Grant Reference
941406
Insulin resistance and obesity from vascular shunting in muscle (1992 - 1994)$266,078
Funding
National Health & Medical Research Council ($266,078)
Scheme
Grant-MRC Project
Administered By
University of Tasmania
Research Team
Clark MG; Colquhoun EQ; Rattigan S
Period
1992 - 1994
Grant Reference
921081
Development of pharmacological and dietary factors for the control of obesity (1990 - 1991)$75,115
Funding
National Health & Medical Research Council ($75,115)
Scheme
Grant-MRC Project
Administered By
University of Tasmania
Research Team
Clark MG; Colquhoun EQ; Montgomery IM; Rattigan S
Period
1990 - 1991
Grant Reference
900489
Glucose transport in normal and diabetic vascular smooth muscle (1990)$15,000
Funding
Diabetes Australia Research Trust ($15,000)
Scheme
Grant-Research [1 year]
Administered By
University of Tasmania
Research Team
Clark MG; Colquhoun EQ; Rattigan S
Year
1990

Research Supervision

Professor Rattigan as supervised over 25 successful PhD students, and is currently supervising 3 PhD candidates.

Completed

24

Completed

DegreeTitleCompleted
PhDRole of Adipose Tissue Microvascular Blood Flow in Type 2 Diabetes
Candidate: Donghua Hu
2018
PhDInflammation is Not a Contributing Factor in the Development of Insulin Resistance in Diet Induced Obesity in Rats
Candidate: Aascha Adriana Brown
2017
PhDCharacterisation of Flowmotion in Healthy Controls and Type 2 Diabetes
Candidate: Sarah Joan Blackwood
2017
PhDEffect of the Green Tea Polyphenol, EGCG, on Insulin Sensitivity
Candidate: Huei Leng Helena Ng
2014
PhDExercise Haemodynamics: Physiology and Clinical Consequences
Candidate: Martin Gregory Schultz
2013
PhDMicrovascular Dysfunction and the Development of Muscle Insulin Resistance
Candidate: Dino Premilovac
2012
PhDHemodynamic and Metabolic Actions of Adiponectin in Muscle
Candidate: Carol Therese Bussey
2011
PhDRole of the Microvasculature in the Development of Muscle Insulin Resistance
Candidate: Philippe St-Pierre
2010
MastersVascular and Metabolic Actions of Insulin and AMPK Activation in Muscle
Candidate: Eloise Alice Bradley
2009
PhDEnhancing Blood Flow and Glucose Uptake in Insulin-Resistant Skeletal Muscle
Candidate: Amanda Joan Genders
2009
PhDExercise and Insulin: Muscle Haemodynamics and Metabolism
Candidate: Renee Dwyer
2007
PhDGlucose Uptake in Skeletal Muscle
Candidate: Cathryn Mary Kolka
2006
PhDInsulin-Mediated Capillary Recruitment: Regulatory and Anatomical Aspects
Candidate: Lei Zhang
2005
PhDHemodynamic and metabolic changes in muscle in relation to insulin action
Candidate: Hema Mahajan
2005
PhDNovel Technologies and Measurement of Microvascular Blood Flow in Muscle
Candidate: Andrew Douglas Hastings Clark
2005
PhDInteractions between contraction, insulin and thiazolidinediones in skeletal muscle; a focus on capillary recruitment
Candidate: Catherine Mary Wheatley
2004
PhDRelationship of microvascular flow distibution to skeletal muscle metabolism
Candidate: John Malcolm Newman
2002
PhDRegulation of skeletal muscle metabolism
Candidate: Carla Francesconi
2002
PhDVascular & metabolic actions of insulin
Candidate: Michelle Gaye Wallis
2002
PhDMuscle fuel uptake: a result of hormone and substrate interaction affecting regional blood flow
Candidate: Lucy Henrietta Clerk
2002
PhDVascular effects of vasoconstrictors on muscle metabolism
Candidate: Michelle Anne Vincent
2000
PhDNutritive and Non-Nutritive Blood Flow in Muscle
Candidate: Joanne Maree Youd
2000
PhDVascular control and hindlimb metabolism
Candidate: Chung Ying Alex Tong
1998
PhDTitle: The release of purine and pyrimidine nucleotide catabolites from working blood vessels
Candidate: Stephen Michael Richards
1993