Jonathan’s research is in mathematical and statistical phylogenetics. Phylogenetics is the study of the evolutionary relationships between taxa (e.g. species) using genetic data, e.g. DNA sequences.
His research involves phylogenetic profiling of gene presence/absence data, with the aim of determining associations between genes and their functions, including whether gene presence/absence is compatible with phenotypic traits.
With his University of Alaska Fairbanks colleagues, Jonathan is developing new statistical tests and model selection procedures for the multispecies coalescent model of incomplete lineage sorting. This work involves generalizing the likelihood ratio testing and model selection framework to be more widely applicable to models of incomplete lineage sorting. The MSCquartets R package, developed by Jonathan and his colleagues, performs these tests and continued work is to implement the model selection procedures.
Jonathan has several collaborations at UTAS, including with Barbara Holland, Jeremy Sumner, Ben Halliwell and the UTAS Theoretical Phylogenetics Group. Internationally, Jonathan collaborates with Elizabeth Allman and John Rhodes of the University of Alaska Fairbanks.
Phylogenetic profiling of gene associations, function and genotypes to phenotypes (with Barbara Holland)
Fields of Research
- Biological mathematics (490102)
- Expanding knowledge in the mathematical sciences (280118)
Journal Article(1 outputs)
|2018||Mitchell JD, Sumner JG, Holland BR, 'Distinguishing between convergent evolution and violation of the molecular clock for three taxa', Systematic Biology, 67, (5) pp. 905-915. ISSN 1063-5157 (2018) [Refereed Article]|
Citations: Scopus - 2Web of Science - 1
Co-authors: Sumner JG; Holland BR