Vanni Caruso

UTAS Home Dr Vanni Caruso

Vanni Caruso

Lecturer in Pharmacy Practice

Room 4013 , Pharmacy

+61 6226 1095 (phone)

Dr Vanni Caruso is a medical researcher and lecturer in Pharmacology at the School of Medicine within the Division of Pharmacy. His research interests are in the field of neuroendocrine diseases.


Before joining the University of Tasmania, Vanni worked as postdoctoral fellow at the Department of Neuroscience, Uppsala University (Sweden). He obtained his PhD at the UNSW, Sydney and his MPharm at the University of Bologna, Italy.

Career summary


  • PhD - Endocrine and metabolic changes in offspring due to maternal obesity. University of New South Wales, Australia. 17/12/2012.

Languages (other than English)



Professional practice

Scientific committee member of the Scientific Institute of Algological Science (ISAL), Italy


Neuroendocrine disorders, obesity, energy homeostasis, developmental programming, melanocortin system, FTO, GPCR, pain, synaptic plasticity, reward mechanisms.

Teaching expertise


Teaching responsibility

View more on Dr Vanni Caruso in WARP


  • Neuroendocrine diseases
  • Foetal programming of adult disease
  • Obesity
  • Characterization of novel genes in obesity
  • Reward mechanisms
  • Pain

Research Themes

Vanni leads and coordinates interdisciplinary projects between cross departmental research groups in the field of neuroscience and metabolic disorders for clinical and pre-clinical studies. His research focuses on neuroendocrine diseases and converges on the causes of obesity, nociception and cognitive impairments. He is trying to characterise newly identified genes coding for solute carriers involved in the regulation of energy homeostasis and food reward mechanisms. Parallel to obesity, other focus of his research is on cognitive disorders, particularly on the molecular mechanisms leading to glutamate-induced changes in synaptic plasticity within memory and pain.

Fields of Research

  • Pharmaceutical sciences (321405)
  • Pharmacology and pharmaceutical sciences (321499)
  • Analytical biochemistry (310101)
  • Medicine, nursing and health curriculum and pedagogy (390110)
  • Behavioural neuroscience (520202)
  • Central nervous system (320903)
  • Signal transduction (310111)
  • Basic pharmacology (321401)
  • Health services and systems (420399)
  • Cell neurochemistry (310104)
  • Infectious diseases (320211)
  • Cell metabolism (310103)
  • Exercise physiology (420702)
  • Sports science and exercise (420799)
  • Gastroenterology and hepatology (320209)

Research Objectives

  • Clinical health (200199)
  • Diagnosis of human diseases and conditions (200101)
  • Treatment of human diseases and conditions (200105)
  • Prevention of human diseases and conditions (200104)
  • Other health (209999)
  • Expanding knowledge in psychology (280121)
  • Health policy evaluation (200205)
  • Public health (excl. specific population health) (200499)
  • Expanding knowledge in the mathematical sciences (280118)
  • Assessment, development and evaluation of curriculum (160301)
  • Higher education (160102)


Total publications


Journal Article

(18 outputs)
2022Zuccarini M, Giuliani P, Di Liberto V, Frinchi M, Caciagli F, et al., 'Adipose stromal/stem cell-derived extracellular vesicles: potential next-generation anti-obesity agents', International Journal of Molecular Sciences, 23, (3) Article 1543. ISSN 1422-0067 (2022) [Refereed Article]

DOI: 10.3390/ijms23031543 [eCite] [Details]


2021Ahmad T, Eapen MS, Ishaq M, Park AY, Karpiniec SS, et al., 'Anti-inflammatory activity of fucoidan extracts in vitro', Marine Drugs, 19, (12) pp. 1-17. ISSN 1660-3397 (2021) [Refereed Article]

DOI: 10.3390/md19120702 [eCite] [Details]

Citations: Scopus - 3Web of Science - 3

Co-authors: Ahmad T; Eapen MS; Ishaq M; Sohal SS; Guven N; Eri R


2021Bereznicki BJ, Caruso V, Errey JA, Parker L, Sward J, et al., 'Interprofessional education for pre-clinical medicine, paramedicine and pharmacy students', Medical Education pp. 1-2. ISSN 0308-0110 (2021) [Contribution to Refereed Journal]

DOI: 10.1111/medu.14511 [eCite] [Details]

Citations: Scopus - 1Web of Science - 1

Co-authors: Bereznicki BJ; Errey JA; Parker L; Sward J; Williams A-MM


2021Chan Y, Ng SW, Tan JZX, Gupta G, Negi P, et al., 'Natural products in the management of obesity: Fundamental mechanisms and pharmacotherapy', South African Journal of Botany, 143 pp. 176-197. ISSN 0254-6299 (2021) [Refereed Article]

DOI: 10.1016/j.sajb.2021.07.026 [eCite] [Details]


2021Ciregia F, Cetani F, Pardi E, Soggiu A, Piras C, et al., 'Parathyroid carcinoma and adenoma co-existing in one patient: case report and comparative proteomic analysis', Cancer Genomics and Proteomics, 18, (6) pp. 781-796. ISSN 1109-6535 (2021) [Refereed Article]

DOI: 10.21873/cgp.20297 [eCite] [Details]

Citations: Scopus - 1Web of Science - 1


2021Ishaq M, Tran DT, Wu Y, Nowak K, Deans BJ, et al., 'Asperuloside enhances taste perception and prevents weight gain in high-fat fed mice', Frontiers in Endocrinology, 12 pp. 1-11. ISSN 1664-2392 (2021) [Refereed Article]

DOI: 10.3389/fendo.2021.615446 [eCite] [Details]

Citations: Scopus - 2Web of Science - 1

Co-authors: Ishaq M; Tran DT; Wu Y; Deans BJ; Southam B; Vicenzi S; Randall C; Yang C; Tan E; Ahmad T; Shastri M; Bleasel M; Scowen P; Jacobson G; Bissember AC; Smith JA; Eri R; Canales J; Iglesias M; Guven N


2021Tran DT, Myers S, McGowan C, Henstridge D, Eri R, et al., '1-deoxysphingolipids, early predictors of type 2 diabetes, compromise the functionality of skeletal myoblasts', Frontiers in Endocrinology, 12 Article 772925. ISSN 1664-2392 (2021) [Refereed Article]

DOI: 10.3389/fendo.2021.772925 [eCite] [Details]

Co-authors: Tran DT; Myers S; McGowan C; Henstridge D; Eri R; Sonda S


2020Chan Y, Ng SW, Xin Tan JZ, Gupta G, Tambuwala MM, et al., 'Emerging therapeutic potential of the iridoid molecule, asperuloside: A snapshot of its underlying molecular mechanisms', Chemico-Biological Interactions, 315 pp. 1-10. ISSN 0009-2797 (2020) [Refereed Article]

DOI: 10.1016/j.cbi.2019.108911 [eCite] [Details]

Citations: Scopus - 9Web of Science - 11

Co-authors: Ishaq M


2019Vicario CM, Caruso V, Craparo G, Felmingham K, 'Time is overestimated in obesity: a cohort study', Journal of Health Psychology pp. 1-15. ISSN 1359-1053 (2019) [Refereed Article]

DOI: 10.1177/1359105319842937 [eCite] [Details]

Citations: Scopus - 1Web of Science - 1

Co-authors: Vicario CM


2017Apidi NA, Murugiah MK, Muthuveloo R, Soh YC, Caruso V, et al., 'Mobile medical applications for dosage recommendation, drug adverse reaction, and drug interaction', Therapeutic Innovation & Regulatory Science, 51, (4) pp. 480-485. ISSN 2168-4790 (2017) [Refereed Article]

DOI: 10.1177/2168479017696266 [eCite] [Details]

Citations: Scopus - 19Web of Science - 19

Co-authors: Patel R; Ming LC


2016Caruso V, Sreedharan S, Carlini VP, Jacobsson JA, Haitina T, et al., 'mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts', Gene: An International Journal Focusing on Gene Cloning and Gene Structure and Function, 581, (2) pp. 139-45. ISSN 0378-1119 (2016) [Refereed Article]

DOI: 10.1016/j.gene.2016.01.044 [eCite] [Details]

Citations: Scopus - 3Web of Science - 3


2015Caruso V, Le Greves M, Fard SS, Haitina T, Olszewski K, et al., 'The Orphan G Protein-Coupled Receptor Gene GPR178 Is Evolutionary Conserved and Altered in Response to Acute Changes in Food Intake', PLoS One, 10, (6) Article e0122061. ISSN 1932-6203 (2015) [Refereed Article]

DOI: 10.1371/journal.pone.0122061 [eCite] [Details]

Citations: Scopus - 1Web of Science - 1


2014Caruso V, Hagglund MG, Badiali L, Bagchi S, Roshanbin S, et al., 'The G protein-coupled receptor GPR162 is widely distributed in the CNS and highly expressed in the hypothalamus and in hedonic feeding areas', Gene, 553, (1) pp. 1-6. ISSN 0378-1119 (2014) [Refereed Article]

DOI: 10.1016/j.gene.2014.09.042 [eCite] [Details]

Citations: Scopus - 2Web of Science - 2


2014Caruso V, Lagerstrom MC, Olszewski PK, Fredriksson R, Schioth HB, 'Synaptic changes induced by melanocortin signalling', Nature Reviews Neuroscience, 15, (2) pp. 98-110. ISSN 1471-003X (2014) [Refereed Article]

DOI: 10.1038/nrn3657 [eCite] [Details]

Citations: Scopus - 55Web of Science - 56


2013Bahari H, Caruso V, Morris MJ, 'Late-Onset Exercise in Female Rat Offspring Ameliorates the Detrimental Metabolic Impact of Maternal Obesity', Endocrinology, 154, (10) pp. 3610-21. ISSN 0013-7227 (2013) [Refereed Article]

DOI: 10.1210/en.2013-1059 [eCite] [Details]

Citations: Scopus - 27Web of Science - 28


2013Caruso V, Bahari H, Morris MJ, 'The Beneficial Effects of Early Short-Term Exercise in the Offspring of Obese Mothers are Accompanied by Alterations in the Hypothalamic Gene Expression of Appetite Regulators and FTO (Fat Mass and Obesity Associated) Gene', Journal of Neuroendocrinology, 25, (8) pp. 742-52. ISSN 0953-8194 (2013) [Refereed Article]

DOI: 10.1111/jne.12053 [eCite] [Details]

Citations: Scopus - 23Web of Science - 23


2011Caruso V, Chen H, Morris MJ, 'Early hypothalamic FTO overexpression in response to maternal obesity--potential contribution to postweaning hyperphagia', PloS one, 6, (9) Article e25261. ISSN 1932-6203 (2011) [Refereed Article]

DOI: 10.1371/journal.pone.0025261 [eCite] [Details]

Citations: Scopus - 20Web of Science - 19


2011Chen H, Iglesias MA, Caruso V, Morris MJ, 'Maternal Cigarette Smoke Exposure Contributes to Glucose Intolerance and Decreased Brain Insulin Action in Mice Offspring Independent of Maternal Diet', PL o S One, 6, (11) Article e27260. ISSN 1932-6203 (2011) [Professional, Refereed Article]

DOI: 10.1371/journal.pone.0027260 [eCite] [Details]

Citations: Scopus - 35Web of Science - 29


Chapter in Book

(2 outputs)
2017Schioth H, Caruso V, Lagerstrom M, Hills R, 'Prolactin-releasing peptide receptor', IUPHAR/BPS Guide to PHARMACOLOGY, online (2017) [Other Book Chapter]

[eCite] [Details]

2017Tung M, Schioth H, Gantz I, Caruso V, Cone RD, et al., 'Melanocortin receptors', IUPHAR/BPS Guide to PHARMACOLOGY, Online (2017) [Other Book Chapter]

[eCite] [Details]



(2 outputs)
2022Di Iorio P, Ronci M, Giuliani P, Caciagli F, Ciccarelli R, et al., 'Pros and cons of pharmacological manipulation of cGMP-PDEs in the prevention and treatment of breast cancer', International Journal of Molecular Sciences, 23, (1) pp. 1-16. ISSN 1422-0067 (2022) [Substantial Review]

DOI: 10.3390/ijms23010262 [eCite] [Details]


2021Caruso V, Zuccarini M, Di Iorio P, Muhammad I, Ronci M, 'Metabolic changes induced by purinergic signaling: Role in food intake', Frontiers in Pharmacology pp. 1-7. ISSN 1663-9812 (2021) [Substantial Review]

DOI: 10.3389/fphar.2021.655989 [eCite] [Details]

Citations: Scopus - 1Web of Science - 1

Co-authors: Muhammad I


Conference Publication

(8 outputs)
2022Muhammad I, Zuccarini M, Ronci M, Caruso V, 'Asperuloside, a natural compound with potent weight-loss properties: a novel therapeutic purinergic signalling approach for the treatment of obesity', Riunione annuale del purine Club Italiano Programma e Abstract, 28 January, online, pp. 9. (2022) [Conference Extract]

[eCite] [Details]


2019Bereznicki BJ, Caruso V, Errey JA, Parker L, Sward J, et al., 'Learning together: The paramedic, pharmacy and medical student experience of interprofessional education', PAIC 2019, 28-30 November 2019, Hobart, Tasmania (2019) [Plenary Presentation]

[eCite] [Details]

Co-authors: Bereznicki BJ; Errey JA; Parker L; Sward J; Williams A-MM

2017Bahari H, Caruso V, Morris MJ, 'Short term exercise ameliorates metabolic impact of maternal obesity in offspring', Obesity Research & Clinical Practice, pp. 64. ISSN 1871-403X (2017) [Conference Extract]

DOI: 10.1016/j.orcp.2011.08.028 [eCite] [Details]


2017Chowdhury SC, Bahari HB, Caruso VC, Maloney CM, Morris MM, 'Can voluntary exercise in rat offspring reverse renal changes caused by maternal obesity ?', 10th World Congress on Developmental Origins of Health and Disease (DOHaD 2017), 15-18 October 2017, Rotterdam, Netherlands (2017) [Conference Extract]

[eCite] [Details]

2017Chowdhury SS, Bahari H, Caruso V, Maloney CA, Morris MJ, 'Can voluntary exercise improve renal changes in offspring induced by maternal obesity', The FASEB Journal ISSN 1530-6860 (2017) [Conference Extract]

[eCite] [Details]

2012Morris M, Caruso V, Bahari H, 'Can early exercise ameliorate the detrimental impact of maternal obesity on offspring?', Obesity Facts ISSN 1662-4025 (2012) [Conference Extract]

[eCite] [Details]

2011Caruso V, Bahari H, Morris MJ, 'Early exercise intervention ameliorates the detrimental impact of maternal obesity', Obesity Research & Clinical Practice, pp. 34. ISSN 1871-403X (2011) [Conference Extract]

DOI: 10.1016/j.orcp.2011.08.120 [eCite] [Details]


2011Caruso V, Bahari H, Morris MJ, 'Effects of maternal obesity on offspring are exacerbated by overnutrition in adulthood and ameliorated by early exercise intervention', Journal of Developmental Origins of Health and Disease, pp. S29-S29. ISSN 2040-1744 (2011) [Conference Extract]

[eCite] [Details]

Research Supervision

Vanni is looking for highly motivated candidates for PhD projects in the field of neuroendocrine diseases.






PhDFucoidan and its Effects on Inflammation2017
PhDDeveloping Asperuloside, a Newly Compund Important for Food Intake Reduction in Obesity2017
PhDInvestigation of Early Predictors in Insulin Resistance and Type 2 Diabetes Mellitus2018
PhDDoes Obesity Exacerbate Neuroinflammation and Alter the Efficacy of Anti-inflammatory Treatment Following Experimental TBI?2020
PhDDrug Discovery in Obesity Research: asperuloside a new compound for weight loss2021
PhDMemory Consolidation and Reconsolidation of Aversive and Pleasurable Memories in Planaria2021
PhDThe Trace Amine-associated Receptor 1 as a Target for the Development of New Anti-obesity Treatments2022


PhDDeciphering the Role of Serotonin in Brain Circuit Formation
Candidate: Silvia Vicenzi
PhDStrategies to Reduce the Impact of Opioid-Induced Adverse Effects
Candidate: Alok Kumar Paul