Profiles
Eddy Roccati
Eddy Roccati
Research Fellow
Wicking Dementia Research and Education Centre
Room 417E , Medical Science 1, level 4
+61 3 6226 4228 (phone)
Eddy Roccati is a Research Fellow for the Tasmanian Healthy Brain Project at the Wicking Dementia Research and Education Centre. Edward is interested in the epidemiology of neurodegenerative diseases, in particular the preventive potential of modifiable lifestyle risk factors in Alzheimer’s disease and dementia.
Biography
Eddy completed a Bachelor of Science (Neuroscience) and honours degree at the University of Melbourne-Royal Melbourne Hospital and recently submitted his PhD investigating the preventive potential of diet in the preclinical phase of Alzheimer’s disease symptomatology.
Career summary
Qualifications
- PhD, Australian Catholic University, Australia, 2019. Thesis: Preventive potential of diet in the pre-clinical phase of Alzheimer’s disease symptomatology
- BSc (Hons), University of Melbourne – Royal Melbourne Hospital, Australia, 2016. Thesis: The Role of Mediterranean Diet Adherence on Cognitive Function and Beta-Amyloid Deposition in Ageing Australian Women
- BSc, Neuroscience, University of Melbourne, Australia, 2015.
- BA, Sociology, University of Melbourne, Australia, 2012.
Memberships
Professional practice
Australasian Epidemiological Association (Current Student Representative)
Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment
NHMRC National Institute for Dementia Research
Dementia Centre for Research Collaboration
International Research Network for Dementia Prevention
Teaching
Teaching expertise
Biology, physiology and anatomy tutor (Human Body in Health & Disease I & II)
Research Appointments
Australasian Epidemiological Association (Council Member)
View more on Dr Eddy Roccati in WARP
Expertise
Eddy’s research aligns to the University’s research theme of Better Health. His research interests include understanding how lifestyle behaviours contribute to risk of cognitive decline and investigating the preventative potential of modifiable risk factors to alleviate the clinical and physiological manifestations of neurodegenerative disease.
- Epidemiology
- Alzheimer’s disease
- Modifiable lifestyle factors
- Dementia prevention
Collaboration
Eddy is collaborating with researchers from the Menzies Institute for Medical Research and from the Division of Psychology to obtain a cross-disciplinary approach to the Tasmanian Healthy Brain Project.
Awards
Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment – Student Travel Award (2017)
Current projects
Tasmanian Healthy Brain Project (NHMRC funded project)
Fields of Research
- Nutrition and dietetics (321099)
- Neurology and neuromuscular diseases (320905)
- Cognitive neuroscience (520203)
- Central nervous system (320903)
- Geriatrics and gerontology (320210)
- Aged health care (420301)
- Health promotion (420603)
- Health services and systems (420399)
- Preventative health care (420605)
- Epidemiology (420299)
- Sensory systems (320907)
- Epidemiological methods (420204)
- Digital health (420302)
- Neurosciences (320999)
- Behavioural epidemiology (420201)
- Applications in health (460102)
- Primary health care (420319)
- Health psychology (520304)
- Aboriginal and Torres Strait Islander health promotion (450408)
- Sensor technology (incl. chemical aspects) (340108)
- Analytical biochemistry (310101)
- Speech recognition (460212)
Research Objectives
- Mental health (200409)
- Health related to ageing (200502)
- Preventive medicine (200412)
- Nutrition (200410)
- Clinical health (200199)
- Prevention of human diseases and conditions (200104)
- Diagnosis of human diseases and conditions (200101)
- Artificial intelligence (220403)
- Behaviour and health (200401)
- Languages and linguistics (130202)
- Health education and promotion (200203)
- Public health (excl. specific population health) (200499)
- Aboriginal and Torres Strait Islander determinants of health (210301)
- Expanding knowledge in the health sciences (280112)
- Injury prevention and control (200408)
- Health inequalities (200204)
Publications
Total publications
23
Journal Article
(17 outputs)| Year | Citation | Altmetrics |
|---|---|---|
| 2022 | Alty JE, Bai Q, Li R, Lawler K, St George RJ, et al., 'The TAS Test project: a prospective longitudinal validation of new online motor-cognitive tests to detect preclinical Alzheimer's disease and estimate 5-year risks of cognitive decline and dementia', BMC Neurology, 22 Article 266. ISSN 1471-2377 (2022) [Refereed Article] DOI: 10.1186/s12883-022-02772-5 [eCite] [Details] Citations: Scopus - 2Web of Science - 2 Co-authors: Alty JE; Bai Q; Li R; Lawler K; St George RJ; Bindoff A; Garg S; Wang X; Huang G; Zhang K; Rudd KD; Bartlett L; Goldberg LR; Collins JM; Hinder MR; King AE; Vickers JC | |
| 2022 | Alty JE, Bindoff A, Stuart K, Hill E, Collins J, et al., 'Sex-specific protective effects of cognitive reserve on age-related cognitive decline: A 5-Year prospective cohort study', Neurology ISSN 0028-3878 (2022) [Refereed Article] DOI: 10.1212/WNL.0000000000201369 [eCite] [Details] Co-authors: Alty JE; Bindoff A; Stuart K; Collins J; King A; Vickers J | |
| 2022 | Bartlett L, Doherty K, Farrow M, Kim S, Hill E, et al., 'Island Study Linking Aging and Neurodegenerative Disease (ISLAND) targeting dementia risk reduction: protocol for a prospective web-based cohort study', JMIR Research Protocols, 11, (3) Article e34688. ISSN 1929-0748 (2022) [Refereed Article] DOI: 10.2196/34688 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Bartlett L; Doherty K; Farrow M; Kim S; King A; Alty J; Eccleston C; Kitsos A; Bindoff A; Vickers JC | |
| 2022 | Li R, St George RJ, Wang X, Lawler K, Hill E, et al., 'Moving towards intelligent telemedicine: Computer vision measurement of human movement', Computers in Biology and Medicine, 147 Article 105776. ISSN 0010-4825 (2022) [Refereed Article] DOI: 10.1016/j.compbiomed.2022.105776 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Li R; St George RJ; Wang X; Lawler K; Garg S; Bai Q; Alty J | |
| 2021 | Bindoff AD, Summers MJ, Hill E, Alty J, Vickers JC, 'Studying at university in later life slows cognitive decline: A long-term prospective study', Alzheimer's & Dementia: Translational Research & Clinical Interventions pp. 1-10. ISSN 2352-8737 (2021) [Refereed Article] DOI: 10.1002/trc2.12207 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Bindoff AD; Alty J; Vickers JC | |
| 2021 | Collins JM, Hill E, Bindoff A, King AE, Alty J, et al., 'Association Between Components of Cognitive Reserve and Serum BDNF in Healthy Older Adults', Frontiers in Aging Neuroscience, 13 pp. 1-9. ISSN 1663-4365 (2021) [Refereed Article] DOI: 10.3389/fnagi.2021.725914 [eCite] [Details] Citations: Scopus - 6Web of Science - 6 Co-authors: Collins JM; Bindoff A; King AE; Alty J; Summers MJ; Vickers JC | |
| 2021 | Hill E, Alty J, Bartlett L, Goldberg L, Park M, et al., 'Automated analysis of propositional idea density in older adults', Cortex, 145 pp. 264-272. ISSN 0010-9452 (2021) [Refereed Article] DOI: 10.1016/j.cortex.2021.09.018 [eCite] [Details] Citations: Scopus - 1 Co-authors: Alty J; Bartlett L; Goldberg L; Park M; Yeom S; Vickers J | |
| 2021 | Shang X, Hill E, Li Y, He M, 'Energy and macronutrient intakes at breakfast and cognitive declines in community-dwelling older adults: a 9-year follow-up cohort study', American Journal of Clinical Nutrition: A Journal Reporting The Practical Application of Our World-Wide Knowledge of Nutrition ISSN 0002-9165 (2021) [Refereed Article] DOI: 10.1093/ajcn/nqaa403 [eCite] [Details] Citations: Scopus - 9Web of Science - 8 | |
| 2021 | Shang X, Hill E, Zhu Z, Liu J, Ge Z, et al., 'The association of age at diagnosis of hypertension with brain structure and incident dementia in the UK Biobank', Hypertension, 78, (5) pp. 1463-1474. ISSN 0194-911X (2021) [Refereed Article] DOI: 10.1161/HYPERTENSIONAHA.121.17608 [eCite] [Details] Citations: Scopus - 8Web of Science - 9 Co-authors: Wang W | |
| 2021 | Shang X, Hodge AM, Hill E, Zhu Z, He M, 'Associations of dietary pattern and sleep duration with cognitive decline in community-dwelling older adults: A seven-year follow-up cohort study', Journal of Alzheimer's Disease, 82, (4) pp. 1559-1571. ISSN 1387-2877 (2021) [Refereed Article] DOI: 10.3233/JAD-201329 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 | |
| 2020 | Shang X, Peng W, Hill E, Szoeke C, He M, et al., 'Incidence, progression, and patterns of multimorbidity in community- dwelling middle-aged men and women', Frontiers in Public Health, 8 Article 404. ISSN 2296-2565 (2020) [Refereed Article] DOI: 10.3389/fpubh.2020.00404 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 | |
| 2019 | Hill E, Goodwill AM, Gorelik A, Szoeke C, 'Diet and biomarkers of Alzheimer's disease: a systematic review and meta-analysis', Neurobiology of Aging, 76 pp. 45-52. ISSN 0197-4580 (2019) [Refereed Article] DOI: 10.1016/j.neurobiolaging.2018.12.008 [eCite] [Details] Citations: Scopus - 58Web of Science - 54 | |
| 2019 | Hill E, Hodge A, Clifton P, Shivappa N, Hebert JR, et al., 'Longitudinal nutritional changes in aging Australian women', Asia Pacific Journal of Clinical Nutrition, 28, (1) pp. 139-149. ISSN 0964-7058 (2019) [Refereed Article] DOI: 10.6133/apjcn.201903_28(1).0019 [eCite] [Details] Citations: Scopus - 8Web of Science - 6 | |
| 2019 | Shang X, Peng W, Hill E, Szoeke C, He M, et al., 'Incidence of medication-treated depression and anxiety associated with long-term cancer, cardiovascular disease, diabetes and osteoarthritis in community-dwelling women and men', EClinicalMedicine pp. 1-9. ISSN 2589-5370 (2019) [Refereed Article] DOI: 10.1016/j.eclinm.2019.08.010 [eCite] [Details] Citations: Web of Science - 12 | |
| 2019 | Szoeke C, Goodwill AM, Gorelik A, Dennerstein L, Caeyenberghs K, et al., 'Apolipoprotein E4 mediates the association between midlife dyslipidemia and cerebral amyloid in aging women', Journal of Alzheimer's Disease, 68, (1) pp. 105-114. ISSN 1387-2877 (2019) [Refereed Article] DOI: 10.3233/JAD-180815 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 Co-authors: Simpson Jr S | |
| 2018 | Hill E, Clifton P, Goodwill AM, Dennerstein L, Campbell S, et al., 'Dietary patterns and β-amyloid deposition in aging Australian women', Alzheimer's & Dementia, 4 pp. 535-541. ISSN 1552-5260 (2018) [Refereed Article] DOI: 10.1016/j.trci.2018.09.007 [eCite] [Details] Citations: Scopus - 18 | |
| 2018 | Hill E, Szoeke C, Dennerstein L, Campbell S, Clifton P, 'Adherence to the Mediterranean diet Is not related to beta-amyloid deposition: data from the Women's Healthy Ageing Project', Journal of Prevention of Alzheimer's Disease, 5, (2) pp. 137-141. ISSN 2274-5807 (2018) [Refereed Article] DOI: 10.14283/jpad.2018.12 [eCite] [Details] Citations: Web of Science - 10 |
Conference Publication
(6 outputs)| Year | Citation | Altmetrics |
|---|---|---|
| 2021 | Alty J, Bai Q, St George RJ, Bindoff A, Li R, et al., 'TasTest: moving towards a digital screening test for pre-clinical Alzheimer's disease', Biomarkers ISSN 1354-750X (2021) [Conference Extract] DOI: 10.1002/alz.058732 [eCite] [Details] Co-authors: Alty J; Bai Q; St George RJ; Bindoff A; Li R; Lawler K; Garg G; Bartlett L; King AE; Vickers JC | |
| 2021 | Hill E, Collins J, Bindoff A, King A, Alty J, et al., 'Increased age and higher levels of cognitive reserve are associated with lower serum BDNF levels in healthy older adults', Australian Dementia Forum 2021, 31 May - 1 June, virtual (2021) [Conference Extract] Co-authors: Collins J; Bindoff A; King A; Alty J; Summers M; Vickers J | |
| 2020 | Bartlett L, Doherty K, Farrow M, Bindoff A, Kim S, et al., 'Poster - The island study linking ageing and neurodegenerative disease (ISLAND): a longitudinal public health research program targeting dementia risk reduction', 2020 Alzheimer's Association International Conference, 26-30 July 2020, Online (2020) [Conference Extract] Co-authors: Bartlett L; Doherty K; Farrow M; Bindoff A; Kim S; Eccleston C; Alty J; King E; Vickers JC | |
| 2020 | Bartlett L, Doherty K, Farrow M, Bindoff A, Kim S, et al., 'The Island Study Linking Ageing and Neurodegenerative Disease (ISLAND): A longitudinal public health research program targeting dementia risk reduction', Alzheimer's & Dementia ISSN 1552-5260 (2020) [Conference Extract] DOI: 10.1002/alz.045539 [eCite] [Details] Co-authors: Bartlett L; Doherty K; Farrow M; Bindoff A; Kim S; Eccleston C; Alty JE; King AE; Vickers JC | |
| 2020 | Hill E, Bindoff A, Bartlett L, Summers MJ, Vickers JC, 'Exploring uptake of a university-level educational intervention to prevent cognitive decline and reduce dementia risk: The Tasmanian Healthy Brain Project', Alzheimer's & Dementia ISSN 1552-5260 (2020) [Conference Extract] DOI: 10.1002/alz.045477 [eCite] [Details] Co-authors: Bindoff A; Bartlett L; Summers MJ; Vickers JC | |
| 2020 | Hill E, Bindoff IK, Bartlett L, Summers MJ, Vickers JC, 'Exploring uptake of a university-level educational intervention to prevent cognitive decline and reduce dementia risk: the Tasmanian Healthy Brain Project', Alzheimer's Association International Conference 2020, 27 - 31 July 2020, virtual (2020) [Conference Extract] Co-authors: Bindoff IK; Bartlett L; Summers MJ; Vickers JC |
Grants & Funding
Funding Summary
Number of grants
2
Total funding
Projects
- Description
- Alzheimer's disease (AD) starts damaging the brain >10 years before memory problems begin. To reduce dementia incidence, we must detect AD earlier so we can target prevention through early clinical trial recruitment and risk reduction (that could prevent 40% cases). With 10,000 available UTAS research participants and 200 patients from RHH and the community, we aim to develop a test to detect early signs of AD by analysing hand- AND speech- movements using a smartphone and machine learning algorithms.
- Funding
- Royal Hobart Hospital Research Foundation ($446,957)
- Scheme
- Grant-Major Project
- Administered By
- University of Tasmania
- Research Team
- Alty JE; Goldberg LR; Roccati E; Lawler K; Bhagwat A; Fernando N; Bartlett L; Bindoff AD; Bai Q; Vickers JC
- Period
- 2022 - 2024
- Description
- Global dementia prevalence is rising. Alzheimer's disease (AD), the most common cause, has devastating effects on people's quality of life. AD has a preclinical (pre-AD) period of 10-20 years when brain pathology silently progresses before any cognitive symptoms appear. Current tests for pre-AD are invasive, costly and unsuitable for screening at population level. If we can't identify people with pre-AD, we can't offer them early interventions. This hinders our strategies to reduce AD prevalence. We will develop a new scalable test (HandTest) by combining two innovative ideas: hand-movement tests to detect pre-AD >10 years before cognitive symptoms begin; and computer vision so people can self-test online at home. This unique approach builds on the recent discoveries that the posterior cingulate cortex (the first brain region to show abnormalities in pre-AD) is involved in hand-movement control, and that hand-movement patterns change in pre-AD. We will use exquisitely precise computer vision methods to automatically analyse movement data from thousands of participants, who complete the online test by simply opening and closing their hands repeatedly for 5 minutes in front of a standard computer, tablet or smartphone camera. The CI/AI team of experts in hand-movement analysis, pre-AD, computer vision, AD biomarkers and biostatistics has access to 3 well-phenotyped cohorts, >10,000 existing participants and a cutting-edge assay for a blood AD biomarker, ptau181. We will develop a HandTest algorithm to classify hand-movement data for pre-AD risk. In a longitudinal cohort we will determine HandTest's precision to prospectively predict 5-year risks of cognitive decline and AD. This is the critical first step for up-scaling HandTest nationwide via memory clinics of the Australian Dementia Network. With worldwide access to computers, tablets and smartphones increasing, HandTest is scalable globally, potentially transforming dementia prevention and management.
- Funding
- National Health & Medical Research Council ($899,782)
- Scheme
- Grant-Ideas
- Administered By
- University of Tasmania
- Research Team
- Alty JE; Vickers JC; Bai Q; Bindoff AD; Roccati E
- Period
- 2021 - 2025
- Grant Reference
- 2004051
Edward is currently available for HDR supervision.