Profiles
Sukhwinder Sohal
Sukhwinder Sohal
Senior lecturer in Histopathology
Health Sciences (School of )
Newnham Campus
+61 (03) 6324 5434 (phone)
View more on Dr Sukhwinder Sohal in WARP
Fields of Research
- Respiratory diseases (320103)
- Cardiology (incl. cardiovascular diseases) (320101)
- Pharmaceutical sciences (321405)
- Cell metabolism (310103)
- Signal transduction (310111)
- Receptors and membrane biology (310110)
- Analytical biochemistry (310101)
- Genetic immunology (310507)
- Medical bacteriology (320701)
- Clinical sciences (320299)
- Radiation therapy (321110)
- Infectious diseases (320211)
- Veterinary diagnosis and diagnostics (300904)
- Cellular interactions (incl. adhesion, matrix, cell wall) (310105)
- Gene expression (incl. microarray and other genome-wide approaches) (310505)
- Gastroenterology and hepatology (320209)
- Cancer genetics (321103)
- Animal immunology (310905)
- Health and community services (420305)
- Cancer cell biology (321101)
- Neurosciences (320999)
- Community child health (420601)
- Health surveillance (420310)
- Preventative health care (420605)
- Health promotion (420603)
- Pathology (excl. oral pathology) (320220)
- Other psychology (529999)
- Traditional, complementary and integrative medicine (420899)
- Allergy (320401)
- Applied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies) (320402)
- Autoimmunity (320403)
- Innate immunity (320407)
- Solid tumours (321111)
Research Objectives
- Clinical health (200199)
- Diagnosis of human diseases and conditions (200101)
- Public health (excl. specific population health) (200499)
- Treatment of human diseases and conditions (200105)
- Prevention of human diseases and conditions (200104)
- Terrestrial biodiversity (180606)
- Human pharmaceutical treatments (240803)
- Expanding knowledge in the health sciences (280112)
- Preventive medicine (200412)
- Disease distribution and transmission (incl. surveillance and response) (200404)
- Health education and promotion (200203)
- Health inequalities (200204)
- Behaviour and health (200401)
- Social structure and health (200207)
Publications
Total publications
262
Journal Article
(131 outputs)Year | Citation | Altmetrics |
---|---|---|
2022 | Asrani P, Tiwari K, Eapen MS, Hassan MDI, Sohal SS, 'Containment strategies for COVID-19 in India: lessons from the second wave', Expert Review of Anti-infective Therapy, 20, (6) pp. 829-835. ISSN 1478-7210 (2022) [Refereed Article] DOI: 10.1080/14787210.2022.2036605 [eCite] [Details] Citations: Scopus - 5Web of Science - 4 Co-authors: Eapen MS | |
2022 | Asrani P, Tiwari K, Eapen MS, McAlinden KD, Haug G, et al., 'Clinical features and mechanistic insights into drug repurposing for combating COVID-19', International Journal of Biochemistry and Cell Biology, 142 Article 106114. ISSN 1357-2725 (2022) [Refereed Article] DOI: 10.1016/j.biocel.2021.106114 [eCite] [Details] Citations: Scopus - 9Web of Science - 9 Co-authors: Eapen MS; McAlinden KD; Haug G; Flanagan KL | |
2022 | Bhattarai P, Lu W, Gaikwad AV, Dey S, Chia C, et al., 'Arterial remodelling in smokers and in patients with small airway disease and COPD: implications for lung physiology and early origins of pulmonary hypertension', ERJ Open Research, 8, (4) Article 00254-2022. ISSN 2312-0541 (2022) [Refereed Article] DOI: 10.1183/23120541.00254-2022 [eCite] [Details] Co-authors: Bhattarai P; Lu W; Gaikwad AV; Larby J; Haug G; Hardikar A; Williams A; Eapen MS | |
2022 | Brake SJ, Eapen MS, McAlinden KD, Markos J, Haug G, et al., 'SARS-CoV-2 (COVID-19) adhesion site protein upregulation in small airways, type 2 pneumocytes, and alveolar macrophages of smokers and COPD - possible implications for interstitial fibrosis', International Journal of Chronic Obstructive Pulmonary Disease, 17 Article 17. ISSN 1176-9106 (2022) [Refereed Article] DOI: 10.2147/COPD.S329783 [eCite] [Details] Citations: Scopus - 6Web of Science - 6 Co-authors: Brake SJ; Eapen MS; McAlinden KD; Haug G; Larby J; Hardikar A; Lu W | |
2022 | Dey S, Eapen MS, Chia C, Gaikwad AV, Wark PAB, et al., 'Pathogenesis, clinical features of asthma COPD overlap (ACO), and therapeutic modalities', American Journal of Physiology, 322, (1) pp. L64-L83. ISSN 1040-0605 (2022) [Refereed Article] DOI: 10.1152/ajplung.00121.2021 [eCite] [Details] Citations: Scopus - 3Web of Science - 5 Co-authors: Eapen MS; Gaikwad AV | |
2022 | Dey S, Lu W, Weber HC, Young S, Larby J, et al., 'Differential airway remodeling changes were observed in patients with asthma COPD overlap compared to patients with asthma and COPD alone', American Journal of Physiology, 323, (4) pp. 473-483. ISSN 1040-0605 (2022) [Refereed Article] DOI: 10.1152/ajplung.00137.2022 [eCite] [Details] Co-authors: Lu W; Weber HC; Larby J; Haug G; Brake SJ; Myers S; Gaikwad AV; Bhattarai P; Eapen MS | |
2022 | Gaikwad AV, Lu W, Dey S, Bhattarai P, Chia C, et al., 'Vascular remodelling in idiopathic pulmonary fibrosis patients and its detrimental effect on lung physiology: potential role of endothelial-to-mesenchymal transition', ERJ Open Research, 8, (1) Article 00571-2021. ISSN 2312-0541 (2022) [Refereed Article] DOI: 10.1183/23120541.00571-2021 [eCite] [Details] Citations: Scopus - 6Web of Science - 5 Co-authors: Gaikwad AV; Lu W; Bhattarai P; Larby J; Haug G; Myers S; Eapen MS | |
2022 | Habib I, Anjum F, Mohammad T, Sulaimani MN, Shafie A, et al., 'Differential gene expression and network analysis in head and neck squamous cell carcinoma', Molecular and Cellular Biochemistry, 477, (5) pp. 1361-1370. ISSN 0300-8177 (2022) [Refereed Article] | |
2022 | Liu G, Jarnicki AG, Paudel KR, Lu W, Wadhwa R, et al., 'Adverse roles of mast cell chymase-1 in chronic obstructive pulmonary disease', The European Respiratory Journal, 60, (5) ISSN 0903-1936 (2022) [Refereed Article] DOI: 10.1183/13993003.01431-2021 [eCite] [Details] Citations: Scopus - 6 Co-authors: Lu W; Eapen MS | |
2022 | Lu W, Eapen MS, Singhera GK, Markos J, Haug G, et al., 'Angiotensin-converting enzyme 2 (ACE2), transmembrane peptidase serine 2 (TMPRSS2), and furin expression increases in the lungs of patients with idiopathic pulmonary fibrosis (IPF) and lymphangioleiomyomatosis (LAM): implications for SARS-CoV-2 (COVID-19) infections', Journal of Clinical Medicine, 11, (3) Article 777. ISSN 2077-0383 (2022) [Refereed Article] DOI: 10.3390/jcm11030777 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Lu W; Eapen MS; Haug G; Larby J; Brake SJ | |
2022 | Mandal S, Tejaswi T, Janivara R, Srikrishnan S, Thakur P, et al., 'Transcriptomic-based quantification of the epithelial-hybrid-mesenchymal spectrum across biological contexts', Biomolecules, 12, (1) Article 29. ISSN 2218-273X (2022) [Refereed Article] DOI: 10.3390/biom12010029 [eCite] [Details] Citations: Scopus - 5Web of Science - 3 | |
2022 | Sharma P, Singh Dhanjal D, Chopra C, Tambuwala MM, Sohal SS, et al., 'Targeting eosinophils in chronic respiratory diseases using nanotechnology-based drug delivery', Chemico-Biological Interactions, 365 Article 110050. ISSN 0009-2797 (2022) [Refereed Article] DOI: 10.1016/j.cbi.2022.110050 [eCite] [Details] Citations: Web of Science - 1 | |
2022 | Sohal SS, 'Therapeutic Modalities for Asthma, COPD, and Pathogenesis of COVID-19: Insights from the Special Issue', Journal of Clinical Medicine, 11, (15) pp. 1-7. ISSN 2077-0383 (2022) [Contribution to Refereed Journal] DOI: 10.3390/jcm11154525 [eCite] [Details] Citations: Web of Science - 1 | |
2022 | Werder RB, Ullah MA, Rahman MM, Simpson J, Lynch JP, et al., 'Targeting the P2Y13 receptor suppresses IL-33 and HMGB1 release and ameliorates experimental asthma', American Journal of Respiratory and Critical Care Medicine, 205, (3) pp. 300-312. ISSN 1073-449X (2022) [Refereed Article] DOI: 10.1164/rccm.202009-3686OC [eCite] [Details] Citations: Scopus - 13Web of Science - 12 Co-authors: Lu W | |
2021 | Aghaei M, Dastghaib S, Aftabi S, Aghanoori M-R, Alizadeh J, et al., 'The ER Stress/UPR axis in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis', Life, 11, (1) pp. 1-27. ISSN 2075-1729 (2021) [Refereed Article] DOI: 10.3390/life11010001 [eCite] [Details] Citations: Scopus - 14Web of Science - 13 Co-authors: McAlinden KD; Eapen MS | |
2021 | Ahmad T, Eapen MS, Ishaq M, Park AY, Karpiniec SS, et al., 'Anti-inflammatory activity of fucoidan extracts in vitro', Marine Drugs, 19, (12) Article 702. ISSN 1660-3397 (2021) [Refereed Article] DOI: 10.3390/md19120702 [eCite] [Details] Citations: Scopus - 19Web of Science - 18 Co-authors: Ahmad T; Eapen MS; Ishaq M; Guven N; Caruso V; Eri R | |
2021 | AlAjmi MF, Khan S, Choudhury A, Mohammad T, Noor S, et al., 'Impact of deleterious mutations on structure, function and stability of serum/glucocorticoid regulated kinase 1: A gene to diseases correlation', Frontiers in Molecular Biosciences, 8 pp. 1-14. ISSN 2296-889X (2021) [Refereed Article] DOI: 10.3389/fmolb.2021.780284 [eCite] [Details] Citations: Scopus - 5Web of Science - 5 Co-authors: Lu M; Eapen MS | |
2021 | Asrani P, Eapen MS, Chia C, Haug G, Weber HC, et al., 'Diagnostic approaches in COVID-19: clinical updates', Expert Review of Respiratory Medicine, 15, (2) pp. 197-212. ISSN 1747-6348 (2021) [Refereed Article] DOI: 10.1080/17476348.2021.1823833 [eCite] [Details] Citations: Scopus - 31Web of Science - 32 Co-authors: Eapen MS; Haug G; Weber HC | |
2021 | Asrani P, Eapen MS, Hassan MI, Sohal SS, 'Implications of the second wave of COVID-19 in India', The Lancet Respiratory Medicine ISSN 2213-2600 (2021) [Letter or Note in Journal] DOI: 10.1016/S2213-2600(21)00312-X [eCite] [Details] Citations: Scopus - 62Web of Science - 58 Co-authors: Eapen MS | |
2021 | Asrani P, Hussain A, Nasreen K, AlAjmi MF, Amir S, et al., 'Guidelines and Safety Considerations in the Laboratory Diagnosis of SARS-CoV-2 Infection: A Prerequisite Study for Health Professionals', Risk Management and Healthcare Policy, 14 pp. 379-389. ISSN 1179-1594 (2021) [Refereed Article] DOI: 10.2147/RMHP.S284473 [eCite] [Details] Citations: Scopus - 16Web of Science - 16 | |
2021 | Dastghaib S, Kumar S, Aftabi S, Damera G, Dalvand A, et al., 'Mechanisms targeting the unfolded protein response in asthma', American Journal of Respiratory Cell and Molecular Biology, 64, (1) pp. 29-38. ISSN 1044-1549 (2021) [Refereed Article] DOI: 10.1165/rcmb.2019-0235TR [eCite] [Details] Citations: Scopus - 18Web of Science - 17 | |
2021 | Eapen MS, LU W, Hackett TL, Singhera GK, Mahmood MQ, et al., 'Increased myofibroblasts in the small airways, and relationship to remodelling and functional changes in smokers and COPD patients: potential role of epithelial-mesenchymal transition', ERJ Open Research, 7, (2) pp. 1-12. ISSN 2312-0541 (2021) [Refereed Article] DOI: 10.1183/23120541.00876-2020 [eCite] [Details] Citations: Scopus - 15Web of Science - 15 Co-authors: Eapen MS; LU W; Hardikar A; Walters EH | |
2021 | Eapen MS, Lu W, Hackett TL, Singhera GR, Thompson IE, et al., 'Dysregulation of endocytic machinery and ACE2 in small airways of smokers and COPD patients can augment their susceptibility to SARS-CoV-2 (COVID-19) infections', American Journal of Physiology, 320, (1) pp. L158-L163. ISSN 1040-0605 (2021) [Refereed Article] DOI: 10.1152/ajplung.00437.2020 [eCite] [Details] Citations: Scopus - 14Web of Science - 13 Co-authors: Eapen MS; Lu W; Thompson IE; McAlinden KD; Hardikar A; Weber HC; Haug G | |
2021 | Hussain MS, Sharma P, Dhanjal DS, Khurana N, Vyas M, et al., 'Nanotechnology based advanced therapeutic strategies for targeting interleukins in chronic respiratory diseases', Chemico-Biological Interactions, 348 pp. 1-12. ISSN 0009-2797 (2021) [Refereed Article] DOI: 10.1016/j.cbi.2021.109637 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 | |
2021 | Liu G, Philp AM, Corte T, Travis MA, Schilter H, et al., 'Therapeutic targets in lung tissue remodelling and fibrosis', Pharmacology and Therapeutics, 225 pp. 1-34. ISSN 0163-7258 (2021) [Refereed Article] DOI: 10.1016/j.pharmthera.2021.107839 [eCite] [Details] Citations: Scopus - 56Web of Science - 47 Co-authors: Eapen MS | |
2021 | McAlinden KD, Barnsley K, Weber HC, Haug G, Chia C, et al., 'Cochrane review update leaves big questions unanswered regarding vaping: implications for medical practitioners', The European Respiratory Journal, 57, (5) pp. 1-4. ISSN 0903-1936 (2021) [Letter or Note in Journal] DOI: 10.1183/13993003.00022-2021 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 Co-authors: McAlinden KD; Barnsley K; Weber HC; Haug G; Eapen MS | |
2021 | McAlinden KD, LU W, Eapen MS, Sohal SS, 'Electronic cigarettes: Modern instruments for toxic lung delivery and posing risk for the development of chronic disease', Electronic cigarettes: Modern instruments for toxic lung delivery and posing risk for the development of chronic disease, 137 pp. 1-5. ISSN 1878-5875 (2021) [Refereed Article] DOI: 10.1016/j.biocel.2021.106039 [eCite] [Details] Citations: Scopus - 10Web of Science - 8 Co-authors: McAlinden KD; LU W; Eapen MS | |
2021 | McAlinden KD, LU W, Vahidi Ferdowsi P, Myers S, Markos J, et al., 'Electronic cigarette aerosol is cytotoxic and increases ACE2 expression on human airway epithelial cells: Implications for SARS-CoV-2 (COVID-19)', Journal of Clinical Medicine, 10, (5) pp. 1-18. ISSN 2077-0383 (2021) [Refereed Article] DOI: 10.3390/jcm10051028 [eCite] [Details] Citations: Scopus - 19Web of Science - 18 Co-authors: McAlinden KD; LU W; Myers S; Larby J; Weber HC; Haug G; Eapen MS | |
2021 | Noor S, Mohammad T, Farhat J, Bilgrami AL, Eapen MS, et al., 'Mechanistic insights into the role of serum-glucocorticoid kinase 1 in diabetic nephropathy: A systematic review', International Journal of Biological Macromolecules, 193, (Pt A) pp. 562-573. ISSN 0141-8130 (2021) [Refereed Article] DOI: 10.1016/j.ijbiomac.2021.10.165 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Eapen MS | |
2021 | Singh J, Thachil T, Eapen MS, Lim A, Sufyan W, et al., 'Immunohistochemical investigation of cytokine expression levels as biomarkers in transrectal ultrasound‑guided needle biopsy specimens of prostate adenocarcinoma', Molecular and Clinical Oncology, 15 pp. 1-8. ISSN 2049-9450 (2021) [Refereed Article] DOI: 10.3892/mco.2021.2353 [eCite] [Details] Citations: Web of Science - 1 Co-authors: Eapen MS | |
2021 | Wark PA, Pathinayake PS, Eapen MS, Sohal SS, 'Asthma, COPD and SARS-CoV-2 infection (COVID-19): potential mechanistic insights', The European Respiratory Journal ISSN 0903-1936 (2021) [Letter or Note in Journal] DOI: 10.1183/13993003.00920-2021 [eCite] [Details] Citations: Scopus - 6Web of Science - 5 Co-authors: Eapen MS | |
2021 | Wark PAB, Pathinayake PS, Kaiko G, Nichol K, Ali A, et al., 'ACE2 expression is elevated in airway epithelial cells from older and male healthy individuals but reduced in asthma', Respirology, 26, (5) pp. 442-451. ISSN 1323-7799 (2021) [Refereed Article] DOI: 10.1111/resp.14003 [eCite] [Details] Citations: Scopus - 40Web of Science - 43 Co-authors: Eapen MS | |
2020 | Asrani P, Hasan GM, Sohal SS, Hassan MI, 'Molecular basis of pathogenesis of coronaviruses: A comparative genomics approach to planetary health to prevent zoonotic outbreaks in the 21st century', OMICS, 24 pp. 1-11. ISSN 1536-2310 (2020) [Refereed Article] DOI: 10.1089/omi.2020.0131 [eCite] [Details] Citations: Scopus - 33Web of Science - 34 | |
2020 | Barnsley K, Sohal SS, 'COVID-19, propelled by smoking, could destroy entire nations', European Respiratory Society - blog, 30 March 2020 (2020) [Contribution to Refereed Journal] Co-authors: Barnsley K | |
2020 | Barnsley K, Sohal SS, 'Covid-19 and smoking: the elephant in the room?', BMJ - blog, 24 March 2020 (2020) [Contribution to Refereed Journal] Co-authors: Barnsley K | |
2020 | Bhattarai P, Myers S, Chia C, Weber HC, Young S, et al., 'Clinical application of forced oscillation technique (FOT) in early detection of airway changes in smokers', Journal of Clinical Medicine, 9 pp. 1-12. ISSN 2077-0383 (2020) [Refereed Article] DOI: 10.3390/jcm9092778 [eCite] [Details] Citations: Scopus - 12Web of Science - 12 Co-authors: Bhattarai P; Myers S; Weber HC; Williams AD | |
2020 | Brake SJ, Barnsley KI, Lu W, McAlinden KD, Eapen MS, et al., 'Smoking upregulates angiotensin-converting enzyme-2 receptor: A potential adhesion site for Novel Coronavirus SARS-CoV-2', Journal of Clinical Medicine, 9, (3) Article 841. ISSN 2077-0383 (2020) [Refereed Article] DOI: 10.3390/jcm9030841 [eCite] [Details] Citations: Scopus - 315Web of Science - 308 Co-authors: Brake SJ; Barnsley KI; Lu W; McAlinden KD; Eapen MS | |
2020 | Eapen MS, Lu W, Gaikwad AV, Bhattarai P, Chia C, et al., 'Endothelial to mesenchymal transition: a precursor to post-COVID-19 interstitial pulmonary fibrosis and vascular obliteration?', The European Respiratory Journal, 56, (4) ISSN 0903-1936 (2020) [Letter or Note in Journal] DOI: 10.1183/13993003.03167-2020 [eCite] [Details] Citations: Scopus - 40Web of Science - 36 Co-authors: Eapen MS; Lu W; Gaikwad AV; Bhattarai P; Hardikar A; Haug G | |
2020 | Eapen MS, Sohal SS, 'WNT/β-catenin pathway: A novel therapeutic target for attenuating airway remodelling and EMT in COPD', EBioMedicine ISSN 2352-3964 (2020) [Letter or Note in Journal] DOI: 10.1016/j.ebiom.2020.103095 [eCite] [Details] Citations: Scopus - 8Web of Science - 8 Co-authors: Eapen MS | |
2020 | Gaikwad AV, Eapen MS, McAlinden KD, Chia C, Larby J, et al., 'Endothelial to mesenchymal transition (EndMT) and vascular remodeling in pulmonary hypertension and idiopathic pulmonary fibrosis', Expert Review of Respiratory Medicine, 14, (10) pp. 1027-1043. ISSN 1747-6348 (2020) [Refereed Article] DOI: 10.1080/17476348.2020.1795832 [eCite] [Details] Citations: Scopus - 28Web of Science - 25 Co-authors: Gaikwad AV; Eapen MS; McAlinden KD; Larby J; Myers S; Haug G | |
2020 | Gundamaraju R, Lu W, Azimi I, Eri R, Sohal SS, 'Endogenous anti-cancer candidates in GPCR, ER stress, and EMT', Biomedicines, 8, (10) Article 402. ISSN 2227-9059 (2020) [Refereed Article] DOI: 10.3390/biomedicines8100402 [eCite] [Details] Citations: Scopus - 6Web of Science - 5 Co-authors: Lu W; Azimi I; Eri R | |
2020 | Haug G, Eapen MS, Sohal SS, 'Renin-Angiotensin-Aldosterone System Inhibitors in Covid-19', New England Journal of Medicine, 382, (24) Article 92. ISSN 0028-4793 (2020) [Letter or Note in Journal] DOI: 10.1056/NEJMc2013707 [eCite] [Details] Citations: Scopus - 6Web of Science - 23 Co-authors: Haug G; Eapen MS | |
2020 | Kumari P, Singh A, Ngasainao MR, Shakeel I, Kumar S, et al., 'Potential diagnostics and therapeutic approaches in COVID-19', Clinica Chimica Acta, 510 pp. 488-497. ISSN 0009-8981 (2020) [Refereed Article] DOI: 10.1016/j.cca.2020.08.013 [eCite] [Details] Citations: Scopus - 29Web of Science - 26 | |
2020 | McAlinden KD, Eapen MS, Lu W, Chia C, Haug G, et al., 'COVID-19 and vaping: risk for increased susceptibility to SARS-CoV-2 infection?', The European Respiratory Journal, 56, (1) ISSN 0903-1936 (2020) [Letter or Note in Journal] DOI: 10.1183/13993003.01645-2020 [eCite] [Details] Citations: Scopus - 34Web of Science - 33 Co-authors: McAlinden KD; Eapen MS; Lu W; Haug G | |
2020 | McAlinden KD, Eapen MS, Lu W, Sharma P, Sohal SS, 'The rise of electronic nicotine delivery systems and the emergence of electronic-cigarette-driven disease', American Journal of Physiology: Lung Cellular and Molecular Physiology, 319, (4) pp. L585-L595. ISSN 1040-0605 (2020) [Refereed Article] DOI: 10.1152/ajplung.00160.2020 [eCite] [Details] Citations: Scopus - 28Web of Science - 26 Co-authors: McAlinden KD; Eapen MS; Lu W | |
2020 | McAlinden KD, Eapen MS, Lu W, Sharma P, Sohal SS, 'The ill effects of IQOS on airway cells: Let's not get burned all over again', American Journal of Respiratory Cell and Molecular Biology, 63, (2) pp. 269-270. ISSN 1535-4989 (2020) [Letter or Note in Journal] DOI: 10.1165/rcmb.2020-0094LE [eCite] [Details] Citations: Scopus - 6Web of Science - 6 Co-authors: McAlinden KD; Eapen MS; Lu W | |
2020 | Shastri S, Shinde TS, Sohal SS, Gueven N, Eri R, 'Idebenone Protects against Acute Murine Colitis via Antioxidant and Anti-Inflammatory Mechanisms', International Journal of Molecular Sciences, 21, (2) pp. 1-21. ISSN 1422-0067 (2020) [Refereed Article] DOI: 10.3390/ijms21020484 [eCite] [Details] Citations: Scopus - 24Web of Science - 23 Co-authors: Shinde TS; Gueven N; Eri R | |
2020 | Shinde TS, Hansbro PM, Sohal SS, Dingle P, Eri R, et al., 'Microbiota modulating nutritional approaches to countering the effects of viral respiratory infections including SARS-CoV-2 through promoting metabolic and immune fitness with probiotics and plant bioactives', Microorganisms, 8, (6) Article 921. ISSN 2076-2607 (2020) [Refereed Article] DOI: 10.3390/microorganisms8060921 [eCite] [Details] Citations: Scopus - 41Web of Science - 36 Co-authors: Shinde TS; Eri R; Stanley R | |
2020 | Singh J, Sohal SS, Ahuja K, Lim A, Duncan H, et al., 'Investigation of circulatory cytokines in patients undergoing intensity-modulated radiotherapy (IMRT) for adenocarcinoma of the prostate and association with acute RT-induced toxicity: A prospective clinical study', Cytokine, 131 pp. 1-6. ISSN 1043-4666 (2020) [Refereed Article] DOI: 10.1016/j.cyto.2020.155108 [eCite] [Details] Citations: Web of Science - 1 Co-authors: Ahuja K | |
2020 | Singh J, Sohal SS, Ahuja K, Lim A, Duncan H, et al., 'Levels of plasma cytokine in patients undergoing neoadjuvant androgen deprivation therapy and external beam radiation therapy for adenocarcinoma of the prostate', Annals of Translational Medicine, 8, (10) pp. 1-7. ISSN 2305-5839 (2020) [Refereed Article] DOI: 10.21037/atm-19-1913 [eCite] [Details] Citations: Web of Science - 1 Co-authors: Ahuja K | |
2020 | Vahidi Ferdowsi P, Ng R, Adulcikas J, Sohal SS, Myers S, 'Zinc modulates several transcription-factor regulated pathways in mouse skeletal muscle cells', Molecules, 25, (21) Article 5098. ISSN 1420-3049 (2020) [Refereed Article] DOI: 10.3390/molecules25215098 [eCite] [Details] Citations: Scopus - 9Web of Science - 7 Co-authors: Ng R; Adulcikas J; Myers S | |
2019 | Adulcikas J, Sonda S, Norouzi S, Sohal SS, Myers S, 'Targeting the zinc transporter ZIP7 in the treatment of insulin resistance and type 2 diabetes', Nutrients, 11, (2) pp. 1-15. ISSN 2072-6643 (2019) [Refereed Article] DOI: 10.3390/nu11020408 [eCite] [Details] Citations: Scopus - 19Web of Science - 17 Co-authors: Adulcikas J; Sonda S; Norouzi S; Myers S | |
2019 | Atto B, Eapen MS, Sharma P, Frey U, Ammit AJ, et al., 'New therapeutic targets for the prevention of infectious acute exacerbations of COPD: role of epithelial adhesion molecules and inflammatory pathways', Clinical Science, 133, (14) pp. 1663-1703. ISSN 0143-5221 (2019) [Refereed Article] DOI: 10.1042/CS20181009 [eCite] [Details] Citations: Scopus - 26Web of Science - 26 Co-authors: Atto B; Eapen MS; Larby J; Haug G; Weber HC; Mabeza G; Tristram S; Myers S; Geraghty DP; Flanagan K | |
2019 | Eapen MS, Gaikwad AV, Thompson IE, Lu W, Myers S, et al., 'The effectiveness of immunosuppressive cyclosporin in attenuating the progression of interstitial lung diseases', Journal of Thoracic Disease, 11 pp. S1139-S1142. ISSN 2072-1439 (2019) [Letter or Note in Journal] DOI: 10.21037/jtd.2019.04.44 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 Co-authors: Eapen MS; Gaikwad AV; Thompson IE; Lu W; Myers S | |
2019 | Eapen MS, Sharma P, Gaikwad AV, Lu W, Myers S, et al., 'Epithelial-mesenchymal transition is driven by transcriptional and post transcriptional modulations in COPD: implications for disease progression and new therapeutics', International Journal of Chronic Obstructive Pulmonary Disease, 14 pp. 1603-1610. ISSN 1178-2005 (2019) [Letter or Note in Journal] DOI: 10.2147/COPD.S208428 [eCite] [Details] Citations: Scopus - 19Web of Science - 17 Co-authors: Eapen MS; Gaikwad AV; Lu W; Myers S | |
2019 | Eapen MS, Sharma P, Moodley YP, Hasnbro PM, Sohal SS, 'Dysfunctional immunity and microbial adhesion molecules in smoking-induced pneumonia', American Journal of Respiratory and Critical Care Medicine, 199, (2) pp. 250-251. ISSN 1073-449X (2019) [Letter or Note in Journal] DOI: 10.1164/rccm.201808-1553LE [eCite] [Details] Citations: Scopus - 18Web of Science - 20 Co-authors: Eapen MS | |
2019 | Eapen MS, Sharma P, Thompson IE, Lu W, Myers S, et al., 'Heparin-binding epidermal growth factor (HB-EGF) drives EMT in patients with COPD: implications for disease pathogenesis and novel therapies', Laboratory Investigation, 99, (2) pp. 150-157. ISSN 0023-6837 (2019) [Refereed Article] DOI: 10.1038/s41374-018-0146-0 [eCite] [Details] Citations: Scopus - 18Web of Science - 20 Co-authors: Eapen MS; Thompson IE; Lu W; Myers S | |
2019 | Eapen MS, Sohal SS, 'Update on the Pathogenesis of COPD', New England Journal of Medicine pp. 2483-2484. ISSN 0028-4793 (2019) [Letter or Note in Journal] Co-authors: Eapen MS | |
2019 | Lu W, Sharma P, Eapen MS, Sohal SS, 'Inhaled corticosteroids attenuate epithelial mesenchymal transition (EMT): implications for COPD and lung cancer prophylaxis', European Respiratory Journal, 54, (1) pp. 1900778. ISSN 0903-1936 (2019) [Letter or Note in Journal] DOI: 10.1183/13993003.00778-2019 [eCite] [Details] Citations: Scopus - 11Web of Science - 11 Co-authors: Lu W; Eapen MS | |
2019 | McAlinden KD, Deshpande DA, Ghavami S, Xenaki D, Sohal SS, et al., 'Autophagy is selectively activated and correlates with airway remodeling in asthma', American Journal of Respiratory Cell and Molecular Biology, 60, (5) pp. 541-553. ISSN 1535-4989 (2019) [Refereed Article] DOI: 10.1165/rcmb.2018-0169OC [eCite] [Details] Citations: Scopus - 86Web of Science - 88 | |
2019 | McAlinden KD, Eapen MS, Ghavami S, Sohal SS, Sharma P, 'Altered Calcium in Ciliary Dysfunction: Potential Role of Endoplasmic Reticulum Stress and Ciliophagy', American Journal of Respiratory Cell and Molecular Biology, 61, (6) pp. 794-795. ISSN 1044-1549 (2019) [Letter or Note in Journal] DOI: 10.1165/rcmb.2019-0157LE [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Eapen MS | |
2019 | McAlinden KD, Sohal SS, Sharma P, 'There can be smoke without fire: warranted caution in promoting electronic cigarettes and heat not burn devices as a safer alternative to cigarette smoking', ERJ open research, 5, (3) ISSN 2312-0541 (2019) [Contribution to Refereed Journal] DOI: 10.1183/23120541.00114-2019 [eCite] [Details] Citations: Scopus - 17Web of Science - 13 | |
2019 | Norouzi S, Adulcikas J, Henstridge DC, Sonda S, Sohal SS, et al., 'The zinc transporter Zip7 is downregulated in skeletal muscle of insulin-resistant cells and in mice fed a high-fat diet', Cells, 8, (7) pp. 663. ISSN 2073-4409 (2019) [Refereed Article] DOI: 10.3390/cells8070663 [eCite] [Details] Citations: Scopus - 9Web of Science - 8 Co-authors: Norouzi S; Adulcikas J; Henstridge DC; Sonda S; Myers S | |
2019 | Singh J, Sohal SS, Lim A, Duncan H, Thachil T, et al., 'Cytokines expression levels from tissue, plasma or serum as promising clinical biomarkers in adenocarcinoma of the prostate: A systematic review of recent findings', Annals of Translational Medicine, 7, (11) pp. 245. ISSN 2305-5839 (2019) [Refereed Article] DOI: 10.21037/atm.2019.05.31 [eCite] [Details] Citations: Web of Science - 9 | |
2019 | Sohal SS, Eapen MS, Naidu VGM, Sharma P, 'IQOS exposure impairs human airway cell homeostasis: Direct comparison with traditional cigarette and e-cigarette', ERJ Open Research, 5, (1) Article 00159-2018. ISSN 2312-0541 (2019) [Refereed Article] DOI: 10.1183/23120541.00159-2018 [eCite] [Details] Citations: Scopus - 72Web of Science - 61 Co-authors: Eapen MS | |
2019 | Weber H, Bassett G, Bartl D, Yusof MM, Sohal SS, et al., 'Successful implementation of evidence-based guidelines in a regional emergency department for children presenting with acute asthma', Australian Journal of Rural Health pp. 1-6. ISSN 1038-5282 (2019) [Refereed Article] DOI: 10.1111/ajr.12544 [eCite] [Details] Citations: Scopus - 1 Co-authors: Bartl D; Yusof MM; Ahuja K; Frandsen M | |
2018 | Adulcikas J, Norouzi S, Bretag L, Sohal SS, Myers S, 'The zinc transporter SLC39A7 (ZIP7) harbours a highly-conserved histidinerich N-terminal region that potentially contributes to zinc homeostasis in the endoplasmic reticulum', Computers in Biology and Medicine, 100 pp. 196-202. ISSN 0010-4825 (2018) [Refereed Article] DOI: 10.1016/j.compbiomed.2018.07.007 [eCite] [Details] Citations: Scopus - 8Web of Science - 8 Co-authors: Adulcikas J; Norouzi S; Myers S | |
2018 | Eapen MS, Hansbro PM, Larssona-Callerfelt AK, Jolly MK, Myers S, et al., 'Chronic obstructive pulmonary disease and lung cancer: underlying pathophysiology and new therapeutic modalities', Drugs, 78, (16) pp. 1717-1740. ISSN 0012-6667 (2018) [Refereed Article] DOI: 10.1007/s40265-018-1001-8 [eCite] [Details] Citations: Scopus - 43Web of Science - 43 Co-authors: Eapen MS; Myers S; Larby J; Haug G; Hardikar A; Weber HC | |
2018 | Eapen MS, Kota A, Vindin H, McAlinden K, Xenaki D, et al., 'Apoptosis signal-regulating kinase 1 inhibition attenuates human airway smooth muscle growth and migration in chronic obstructive pulmonary disease', Clinical Science, 132, (14) pp. 1615-1627. ISSN 0143-5221 (2018) [Refereed Article] DOI: 10.1042/CS20180398 [eCite] [Details] Citations: Scopus - 17Web of Science - 15 Co-authors: Eapen MS | |
2018 | Eapen MS, Myers S, Lu W, Tanghe C, Sharma P, et al., 'sE-cadherin and sVE-cadherin indicate active epithelial/endothelial to mesenchymal transition (EMT and EndoMT) in smokers and COPD: implications for new biomarkers and therapeutics', Biomarkers ISSN 1354-750X (2018) [Contribution to Refereed Journal] DOI: 10.1080/1354750X.2018.1479772 [eCite] [Details] Citations: Scopus - 14Web of Science - 14 Co-authors: Eapen MS; Myers S; Lu W; Tanghe C | |
2018 | Eapen MS, Sohal SS, 'Understanding novel mechanisms of microbial pathogenesis in chronic lung disease: implications for new therapeutic targets', Clinical science, 132, (3) pp. 375-379. ISSN 0143-5221 (2018) [Refereed Article] DOI: 10.1042/CS20171261 [eCite] [Details] Citations: Scopus - 15Web of Science - 15 Co-authors: Eapen MS | |
2018 | Jolly MK, Ward C, Eapen MS, Myers S, Hallgren O, et al., 'Epithelial-mesenchymal transition, a spectrum of states: role in lung development, homeostasis, and disease', Developmental Dynamics, 247, (3) pp. 346-358. ISSN 1058-8388 (2018) [Refereed Article] DOI: 10.1002/dvdy.24541 [eCite] [Details] Citations: Scopus - 132Web of Science - 141 Co-authors: Eapen MS; Myers S | |
2018 | Norouzi S, Adulcikas J, Sohal SS, Myers S, 'Zinc stimulates glucose oxidation and glycemic control by modulating the insulin signaling pathway in human and mouse skeletal muscle cell lines', PLoS One, 13, (1) Article e0191727. ISSN 1932-6203 (2018) [Refereed Article] DOI: 10.1371/journal.pone.0191727 [eCite] [Details] Citations: Scopus - 43Web of Science - 41 Co-authors: Norouzi S; Adulcikas J; Myers S | |
2018 | Perera AP, Fernando R, Shinde TS, Gundamaraju R, Southam B, et al., 'MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice', Scientific Reports, 8 Article 8618. ISSN 2045-2322 (2018) [Refereed Article] DOI: 10.1038/s41598-018-26775-w [eCite] [Details] Citations: Scopus - 168Web of Science - 161 Co-authors: Perera AP; Shinde TS; Southam B; Kunde D; Eri R | |
2018 | Saha P, Johny E, Dangi A, Shinde S, Brake S, et al., 'Impact of maternal air pollution exposure on children's lung health: An Indian perspective', Toxics, 6, (4) Article 68. ISSN 2305-6304 (2018) [Refereed Article] DOI: 10.3390/toxics6040068 [eCite] [Details] Citations: Scopus - 10Web of Science - 11 Co-authors: Brake S; Eapen MS | |
2018 | Sohal SS, 'Inhaled corticosteroids and increased microbial load in COPD: potential role of epithelial adhesion molecules', The European respiratory journal, 51, (2) ISSN 0903-1936 (2018) [Letter or Note in Journal] DOI: 10.1183/13993003.02257-2017 [eCite] [Details] Citations: Scopus - 10Web of Science - 10 | |
2018 | Sohal SS, 'Airway Basal Cell Reprogramming and Epithelial- Mesenchymal Transition: A Potential Key to Understanding Early Chronic Obstructive Pulmonary Disease', American journal of respiratory and critical care medicine, 197, (12) pp. 1644-1645. ISSN 1073-449X (2018) [Letter or Note in Journal] DOI: 10.1164/rccm.201712-2450LE [eCite] [Details] Citations: Scopus - 9Web of Science - 8 | |
2018 | Stammnitz MR, Coorens THH, Gori KC, Hayes DA, Fu B, et al., 'The origins and vulnerabilities of two transmissible cancers in Tasmanian devils', Cancer Cell, 33, (4) Article e15. ISSN 1535-6108 (2018) [Refereed Article] DOI: 10.1016/j.ccell.2018.03.013 [eCite] [Details] Citations: Scopus - 56Web of Science - 57 Co-authors: Hayes DA; Pye RJ; Woods GM | |
2017 | Eapen MS, Hasbro PM, McAlinden K, Kim RY, Ward C, et al., 'Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD)', Scientific reports, 7, (1) Article 13392. ISSN 2045-2322 (2017) [Refereed Article] DOI: 10.1038/s41598-017-13888-x [eCite] [Details] Citations: Scopus - 99Web of Science - 96 Co-authors: Eapen MS; Walters EH | |
2017 | Eapen MS, McAlinden K, Tan D, Weston S, Ward C, et al., 'Profiling cellular and inflammatory changes in the airway wall of mild to moderate COPD', Respirology, 22, (6) pp. 1125-1132. ISSN 1323-7799 (2017) [Refereed Article] DOI: 10.1111/resp.13021 [eCite] [Details] Citations: Scopus - 35Web of Science - 36 Co-authors: Eapen MS; McAlinden K; Tan D; Weston S; Muller HK; Walters EH | |
2017 | Hayes DA, Kunde DA, Taylor RL, Pyecroft SB, Sohal SS, et al., 'ERBB3: A potential serum biomarker for early detection and therapeutic target for devil facial tumour 1 (DFT1)', PLOS One, 12, (6) Article e0177919. ISSN 1932-6203 (2017) [Refereed Article] DOI: 10.1371/journal.pone.0177919 [eCite] [Details] Citations: Scopus - 6Web of Science - 6 Co-authors: Kunde DA; Taylor RL; Snow ET | |
2017 | Mahmood MQ, Reid D, Ward C, Muller HK, Knight DA, et al., 'Transforming growth factor (TGF) β1 and Smad signalling pathways: A likely key to EMT-associated COPD pathogenesis', Respirology, 22, (1) pp. 133-140. ISSN 1323-7799 (2017) [Refereed Article] DOI: 10.1111/resp.12882 [eCite] [Details] Citations: Scopus - 59Web of Science - 58 Co-authors: Mahmood MQ; Reid D; Muller HK; Walters EH | |
2017 | Mahmood MQ, Walters EH, Shukla SD, Weston S, Muller HK, et al., 'β-catenin, Twist and Snail: Transcriptional regulation of EMT in smokers and COPD, and relation to airflow obstruction', Scientific Reports, 7, (1) Article 10832. ISSN 2045-2322 (2017) [Refereed Article] DOI: 10.1038/s41598-017-11375-x [eCite] [Details] Citations: Scopus - 55Web of Science - 53 Co-authors: Mahmood MQ; Walters EH; Shukla SD; Weston S; Muller HK | |
2017 | Mahmood MQ, Ward C, Muller HK, Sohal SS, Walters EH, 'Epithelial mesenchymal transition (EMT) and non-small cell lung cancer (NSCLC): a mutual association with airway disease', Medical Oncology, 34, (4) Article 45. ISSN 1357-0560 (2017) [Refereed Article] DOI: 10.1007/s12032-017-0900-y [eCite] [Details] Citations: Scopus - 89Web of Science - 89 Co-authors: Mahmood MQ; Muller HK; Walters EH | |
2017 | Norouzi S, Adulcikas J, Sohal SS, Myers S, 'Zinc transporters and insulin resistance: therapeutic implications for type 2 diabetes and metabolic disease', Journal of Biomedical Science, 24 pp. 1-10. ISSN 1021-7770 (2017) [Refereed Article] DOI: 10.1186/s12929-017-0394-0 [eCite] [Details] Citations: Scopus - 36Web of Science - 37 Co-authors: Norouzi S; Adulcikas J; Myers S | |
2017 | Shukla SD, Mahmood MQ, Weston S, Latham R, Muller HK, et al., 'The main rhinovirus respiratory tract adhesion site (ICAM-1) is upregulated in smokers and patients with chronic airflow limitation (CAL)', Respiratory research, 18 pp. 1-10. ISSN 1465-9921 (2017) [Refereed Article] DOI: 10.1186/s12931-016-0483-8 [eCite] [Details] Citations: Scopus - 41Web of Science - 38 Co-authors: Shukla SD; Mahmood MQ; Weston S; Latham R; Muller HK; Walters EH | |
2017 | Sohal SS, 'Epithelial and endothelial cell plasticity in chronic obstructive pulmonary disease (COPD)', Respiratory Investigation, 55, (2) pp. 104-113. ISSN 2212-5345 (2017) [Refereed Article] DOI: 10.1016/j.resinv.2016.11.006 [eCite] [Details] Citations: Scopus - 44 | |
2017 | Sohal SS, 'Fluticasone propionate and increased risk of pneumonia in COPD: is it PAFR-dependent?', The International Journal of Chronic Obstructive Pulmonary Disease, 12 pp. 3425-3427. ISSN 1178-2005 (2017) [Letter or Note in Journal] | |
2017 | Sohal SS, Eapen MS, Ward C, Walters EH, 'Epithelial-Mesenchymal Transition: A Necessary New Therapeutic Target in Chronic Obstructive Pulmonary Disease?', American Journal of Respiratory and Critical Care Medicine, 196, (3) pp. 393-394. ISSN 1073-449X (2017) [Letter or Note in Journal] DOI: 10.1164/rccm.201704-0771LE [eCite] [Details] Citations: Scopus - 7Web of Science - 7 Co-authors: Eapen MS; Ward C; Walters EH | |
2017 | Sohal SS, Eapen MS, Ward C, Walters EH, 'Airway inflammation and inhaled corticosteroids in COPD', The European Respiratory Journal, 49 ISSN 0903-1936 (2017) [Letter or Note in Journal] Co-authors: Eapen MS; Ward C; Walters EH | |
2017 | Sohal SS, Hansbro PM, Shukla SD, Eapen MS, Walters EH, 'Potential Mechanisms of Microbial Pathogens in Idiopathic Interstitial Lung Disease', Chest, 152, (4) pp. 899-900. ISSN 0012-3692 (2017) [Letter or Note in Journal] DOI: 10.1016/j.chest.2017.05.024 [eCite] [Details] Citations: Scopus - 11Web of Science - 10 Co-authors: Shukla SD; Eapen MS; Walters EH | |
2017 | Sohal SS, Hansbro PM, Walters EH, 'Epithelial Mesenchymal Transition in Chronic Obstructive Pulmonary Disease, a Precursor for Epithelial Cancers: Understanding and Translation to Early Therapy', Annals of the American Thoracic Society, 14, (9) pp. 1491-1492. ISSN 2325-6621 (2017) [Letter or Note in Journal] DOI: 10.1513/AnnalsATS.201705-387LE [eCite] [Details] Citations: Scopus - 13Web of Science - 12 Co-authors: Walters EH | |
2017 | Sohal SS, Walters EH, 'Essential need for rethink of COPD airway pathology: implications for new drug approaches for prevention of lung cancer as well as small airway fibrosis', International journal of chronic obstructive pulmonary disease, 12 pp. 2677-2679. ISSN 1176-9106 (2017) [Letter or Note in Journal] DOI: 10.2147/COPD.S149092 [eCite] [Details] Citations: Scopus - 6Web of Science - 6 Co-authors: Walters EH | |
2017 | Sohal SS, Walters EH, 'Essential need for rethink of COPD airway pathology: implications for new drug approaches for prevention of lung cancer as well as small airway fibrosis', The International Journal of Chronic Obstructive Pulmonary Disease, 12 pp. 2677-2679. ISSN 1178-2005 (2017) [Letter or Note in Journal] Co-authors: Walters EH | |
2017 | Sohal SS, Walters EH, 'To the editor: Advanced Non-Small-Cell Lung Cancer', New England Journal of Medicine pp. 1998-1999. ISSN 0028-4793 (2017) [Letter or Note in Journal] DOI: 10.1056/NEJMc1712794 [eCite] [Details] Citations: Scopus - 10Web of Science - 11 Co-authors: Walters EH | |
2016 | Eapen MS, Grover R, Ahuja KDK, Williams AD, Sohal SS, 'Ventilatory efficiency slope as a predictor of suitability for surgery in chronic obstructive pulmonary disease patients with lung cancer', The Annals of Translational Medicine pp. 1-4. ISSN 2305-5839 (2016) [Letter or Note in Journal] DOI: 10.21037/atm.2016.07.20 [eCite] [Details] Citations: Scopus - 5Web of Science - 4 Co-authors: Eapen MS; Ahuja KDK; Williams AD | |
2016 | Randall-Demllo S, Fernando R, Brain T, Sohal SS, Cook AL, et al., 'Characterisation of colonic dysplasia-like epithelial atypia in murine colitis', World Journal of Gastroenterology, 22, (37) pp. 8334-8348. ISSN 1007-9327 (2016) [Refereed Article] DOI: 10.3748/wjg.v22.i37.8334 [eCite] [Details] Citations: Scopus - 9Web of Science - 9 Co-authors: Randall-Demllo S; Cook AL; Guven N; Kunde D; Eri R | |
2016 | Shukla SD, Fairbairn RL, Gell DA, Latham RD, Sohal SS, et al., 'An antagonist of the platelet-activating factor receptor inhibits adherence of both nontypeable Haemophilus influenzae and Streptococcus pneumoniae to cultured human bronchial epithelial cells exposed to cigarette smoke', International Journal of Chronic Obstructive Pulmonary Disease, 11, (1) pp. 1647-1655. ISSN 1178-2005 (2016) [Refereed Article] DOI: 10.2147/COPD.S108698 [eCite] [Details] Citations: Scopus - 32Web of Science - 30 Co-authors: Shukla SD; Gell DA; Latham RD; Walters EH; O'Toole RF | |
2016 | Shukla SD, Muller HK, Latham R, Sohal SS, Walters EH, 'Platelet-activating factor receptor (PAFr) is upregulated in small airways and alveoli of smokers and COPD patients', Respirology, 21, (3) Article 12709. ISSN 1323-7799 (2016) [Refereed Article] DOI: 10.1111/resp.12709 [eCite] [Details] Citations: Scopus - 40Web of Science - 36 Co-authors: Shukla SD; Muller HK; Latham R; Walters EH | |
2016 | Sohal SS, 'Endothelial to mesenchymal transition (EndMT): an active process in Chronic Obstructive Pulmonary Disease (COPD)?', Respiratory Research (Print), 17, (20) pp. 1-4. ISSN 1465-9921 (2016) [Letter or Note in Journal] DOI: 10.1186/s12931-016-0337-4 [eCite] [Details] Citations: Scopus - 33Web of Science - 32 | |
2016 | Soltani A, Walters EH, Reid DW, Shukla SD, Nowrin K, et al., 'Inhaled corticosteroid normalizes some but not all airway vascular remodeling in COPD', International Journal of COPD, 11, (1) pp. 2359-2367. ISSN 1178-2005 (2016) [Refereed Article] DOI: 10.2147/COPD.S113176 [eCite] [Details] Citations: Scopus - 32Web of Science - 30 Co-authors: Soltani A; Walters EH; Reid DW; Shukla SD; Nowrin K; Muller HK | |
2015 | Eapen MS, Shukla SD, Mahmood MQ, McAlinden-Volkovickas KD, Eri RD, et al., 'Current understanding of corticosteroid therapy in chronic obstructive pulmonary disease (COPD): an overview', International Journal of Medical and Biological Frontiers, 21, (1) ISSN 1081-3829 (2015) [Non Refereed Article] Co-authors: Eapen MS; Shukla SD; Mahmood MQ; McAlinden-Volkovickas KD; Eri RD; Walters EH | |
2015 | Lean QY, Eri RD, Randall-Demllo S, Sohal SS, Stewart N, et al., 'Orally Administered Enoxaparin Ameliorates Acute Colitis by Reducing Macrophage-Associated Inflammatory Responses', PLoS One, 10, (7) Article e0134259. ISSN 1932-6203 (2015) [Refereed Article] DOI: 10.1371/journal.pone.0134259 [eCite] [Details] Citations: Scopus - 20Web of Science - 16 Co-authors: Lean QY; Eri RD; Randall-Demllo S; Stewart N; Peterson GM; Guven N; Patel RP | |
2015 | Lean QY, Gueven N, Eri RD, Bhatia R, Sohal SS, et al., 'Heparins in ulcerative colitis: proposed and potential reasons for inconsistent clinical outcomes', Expert Review of Clinical Pharmacology, 8, (6) pp. 795-811. ISSN 1751-2433 (2015) [Refereed Article] DOI: 10.1586/17512433.2015.1082425 [eCite] [Details] Citations: Scopus - 12Web of Science - 11 Co-authors: Lean QY; Gueven N; Eri RD; Stewart N; Peterson GM; Patel RP | |
2015 | Mahmood MQ, Sohal SS, Shukla SD, Ward C, Hardikar A, et al., 'Epithelial mesenchymal transition in smokers: large versus small airways and relation to airflow obstruction', International Journal of Chronic Obstructive Pulmonary Disease, 10 pp. 1515-1524. ISSN 1176-9106 (2015) [Refereed Article] DOI: 10.2147/COPD.S81032 [eCite] [Details] Citations: Scopus - 59Web of Science - 57 Co-authors: Mahmood MQ; Shukla SD; Hardikar A; Noor WD; Muller HK; Walters EH | |
2015 | Shastri MD, Stewart N, Eapen M, Peterson GM, Zaidi STR, et al., 'Opposing effects of low molecular weight heparins on the release of inflammatory cytokines from peripheral blood mononuclear cells of asthmatics', PLoS One, 10, (3) Article e0118798. ISSN 1932-6203 (2015) [Refereed Article] DOI: 10.1371/journal.pone.0118798 [eCite] [Details] Citations: Scopus - 21Web of Science - 21 Co-authors: Shastri MD; Stewart N; Eapen M; Peterson GM; Zaidi STR; Guven N; Patel RP | |
2015 | Shastri MD, Stewart N, Horne J, Peterson GM, Gueven N, et al., 'In-vitro suppression of IL-6 and IL-8 release from human pulmonary epithelial cells by non-anticoagulant fraction of enoxaparin', PLoS One, 10, (5) Article 0126763. ISSN 1932-6203 (2015) [Refereed Article] DOI: 10.1371/journal.pone.0126763 [eCite] [Details] Citations: Scopus - 32Web of Science - 29 Co-authors: Shastri MD; Stewart N; Horne J; Peterson GM; Gueven N; Patel RP | |
2015 | Shastri MD, Stewart N, Horne J, Zaidi STR, Sohal SS, et al., 'Non-anticoagulant fractions of enoxaparin suppress inflammatory cytokine release from peripheral blood mononuclear cells of allergic asthmatic individuals', PLoS One, 10, (6) Article e0128803. ISSN 1932-6203 (2015) [Refereed Article] DOI: 10.1371/journal.pone.0128803 [eCite] [Details] Citations: Scopus - 25Web of Science - 22 Co-authors: Shastri MD; Stewart N; Horne J; Zaidi STR; Peterson GM; Korner H; Gueven N; Patel RP | |
2015 | Shukla SD, Sohal SS, O'Toole RF, Eapen MS, Walters EH, 'Platelet activating factor receptor: gateway for bacterial chronic airway infection in chronic obstructive pulmonary disease and potential therapeutic target', Expert Review of Respiratory Medicine, 9, (4) pp. 473-485. ISSN 1747-6348 (2015) [Refereed Article] DOI: 10.1586/17476348.2015.1070673 [eCite] [Details] Citations: Scopus - 23Web of Science - 22 Co-authors: Shukla SD; O'Toole RF; Eapen MS; Walters EH | |
2015 | Sohal SS, 'Chronic Obstructive Pulmonary Disease (COPD) and Lung Cancer: Epithelial Mesenchymal Transition (EMT), the Missing Link?', EBioMedicine, 2, (11) pp. 1677-1685. ISSN 2352-3964 (2015) [Contribution to Refereed Journal] DOI: 10.1016/j.ebiom.2015.10.016 [eCite] [Details] Citations: Scopus - 21Web of Science - 20 | |
2014 | Lean QY, Patel RP, Stewart N, Sohal SS, Guven N, 'Identification of pro-and anti-proliferative oligosaccharides of heparins', Integrative Biology, 6, (1) pp. 90 - 99. ISSN 0974-2816 (2014) [Refereed Article] DOI: 10.1039/c3ib40206a [eCite] [Details] Citations: Scopus - 13Web of Science - 12 Co-authors: Lean QY; Patel RP; Stewart N; Guven N | |
2014 | Nowrin K, Sohal SS, Peterson G, Patel R, Walters EH, 'Epithelial-mesenchymal transition as a fundamental underlying pathogenic process in COPD airways: fibrosis, remodeling and cancer', Expert Reviews in Respiratory Medicine, 8, (5) pp. 547-559. ISSN 1747-6348 (2014) [Refereed Article] DOI: 10.1586/17476348.2014.948853 [eCite] [Details] Citations: Scopus - 73Web of Science - 67 Co-authors: Nowrin K; Peterson G; Patel R; Walters EH | |
2014 | Ojo O, Lagan AL, Rajendran V, Spanjer A, Chen L, et al., 'Pathological changes in the COPD lung mesenchyme - Novel lessons learned from in vitro and in vivo studies', Pulmonary Pharmacology and Therapeutics, 29, (2) pp. 121-128. ISSN 1094-5539 (2014) [Refereed Article] DOI: 10.1016/j.pupt.2014.04.004 [eCite] [Details] Citations: Scopus - 29Web of Science - 27 Co-authors: Chen L | |
2014 | Shastri M, Peterson GM, Stewart NJ, Sohal SS, Patel RP, 'Non-anticoagulant derivatives of heparin for the management of asthma: distant dream or close reality?', Expert Opinion on Investigational Drugs: Authoritative Analysis of Randd Trends, 23, (3) pp. 357-373. ISSN 1354-3784 (2014) [Refereed Article] DOI: 10.1517/13543784.2014.866092 [eCite] [Details] Citations: Scopus - 19Web of Science - 16 Co-authors: Shastri M; Peterson GM; Stewart NJ; Patel RP | |
2014 | Shukla SD, Sohal SS, Mahmood MQ, Reid D, Muller HK, et al., 'Airway epithelial platelet-activating factor receptor expression is markedly upregulated in chronic obstructive pulmonary disease', The International Journal of Chronic Obstructive Pulmonary Disease, 9, (1) pp. 853 - 861. ISSN 1178-2005 (2014) [Refereed Article] DOI: 10.2147/COPD.S67044 [eCite] [Details] Citations: Scopus - 33Web of Science - 31 Co-authors: Shukla SD; Mahmood MQ; Muller HK; Walters EH | |
2014 | Sohal SS, 'Expert Review: European Respiratory Society (ERS) Hot Topic', Breath, 10, (3) pp. 263. ISSN 1810-6838 (2014) [Contribution to Refereed Journal] | |
2014 | Sohal SS, Eapen MS, Shukla SD, Courtney J-M, Mahmood MQ, et al., 'Novel insights into chronic obstructive pulmonary disease (COPD): an overview', EMJ Respiratory, 2 pp. 81-87. ISSN 2054-3166 (2014) [Refereed Article] Co-authors: Eapen MS; Shukla SD; Courtney J-M; Mahmood MQ; Walters EH | |
2014 | Sohal SS, Mahmood MQ, Walters EH, 'Clinical significance of epithelial mesenchymal transition (EMT) in chronic obstructive pulmonary disease (COPD): potential target for prevention of airway fibrosis and lung cancer', Clinical and Translational Medicine, 3, (33) pp. 1-4. ISSN 2001-1326 (2014) [Letter or Note in Journal] DOI: 10.1186/s40169-014-0033-2 [eCite] [Details] Co-authors: Mahmood MQ; Walters EH | |
2014 | Sohal SS, Soltani A, Reid D, Ward C, Wills KE, et al., 'A randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial-mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept study', International Journal of COPD, 9, (1) pp. 533-542. ISSN 1178-2005 (2014) [Refereed Article] DOI: 10.2147/COPD.S63911 [eCite] [Details] Citations: Scopus - 68Web of Science - 65 Co-authors: Soltani A; Reid D; Ward C; Wills KE; Muller HK; Walters EH | |
2014 | Sohal SS, Ward C, Walters EH, 'Importance of epithelial mesenchymal transition (EMT) in COPD and asthma', Thorax EJ ISSN 0040-6376 (2014) [Letter or Note in Journal] DOI: 10.1136/thoraxjnl-2014-205582 [eCite] [Details] Citations: Scopus - 22Web of Science - 21 Co-authors: Walters EH | |
2013 | Sohal SS, Reid D, Soltani A, Weston S, Muller HK, et al., 'Changes in airway histone deacetylase2 in smokers and COPD with inhaled corticosteroids: A randomized controlled trial', PLoS One, 8, (5) Article e64833. ISSN 1932-6203 (2013) [Refereed Article] DOI: 10.1371/journal.pone.0064833 [eCite] [Details] Citations: Scopus - 29Web of Science - 30 Co-authors: Reid D; Soltani A; Weston S; Muller HK; Wood-Baker R; Walters EH | |
2013 | Sohal SS, Walters EH, 'Epithelial mesenchymal transition (EMT) in small airways of COPD patients', Thorax ISSN 0040-6376 (2013) [Letter or Note in Journal] DOI: 10.1136/thoraxjnl-2013-203373 [eCite] [Details] Citations: Scopus - 26Web of Science - 26 Co-authors: Walters EH | |
2013 | Sohal SS, Walters EH, 'Role of epithelial mesenchymal transition (EMT) in chronic obstructive pulmonary disease (COPD)', Respiratory Research, 14 pp. 120. ISSN 1465-9921 (2013) [Letter or Note in Journal] DOI: 10.1186/1465-9921-14-120 [eCite] [Details] Citations: Scopus - 42Web of Science - 42 Co-authors: Walters EH | |
2012 | Grigg J, Walters H, Sohal SS, Wood-Baker R, Reid DW, et al., 'Cigarette smoke and platelet-activating factor receptor dependent adhesion of Streptococcus pneumoniae to lower airway cells', Thorax, 67, (10) pp. 908-913. ISSN 0040-6376 (2012) [Refereed Article] DOI: 10.1136/thoraxjnl-2011-200835 [eCite] [Details] Citations: Scopus - 53Web of Science - 52 Co-authors: Walters H; Wood-Baker R; Reid DW | |
2012 | Soltani A, Ewe YP, Lim Z, Sohal SS, Reid D, et al., 'Mast cells in COPD airways: relationship to bronchodilator responsiveness and angiogenesis', European Respiratory Journal, 39, (6) pp. 1361-1367. ISSN 1399-3003 (2012) [Refereed Article] DOI: 10.1183/09031936.00084411 [eCite] [Details] Citations: Scopus - 25Web of Science - 20 Co-authors: Soltani A; Ewe YP; Lim Z; Weston S; Wood-Baker R; Walters EH | |
2012 | Soltani A, Muller HK, Sohal SS, Reid DW, Weston S, et al., 'Distinctive characteristics of bronchial reticular basement membrane and vessel remodelling in chronic obstructive pulmonary disease (COPD) and in asthma: they are not the same disease', Histopathology, 60, (6) pp. 964-970. ISSN 0309-0167 (2012) [Refereed Article] DOI: 10.1111/j.1365-2559.2011.04147.x [eCite] [Details] Citations: Scopus - 32Web of Science - 31 Co-authors: Soltani A; Muller HK; Weston S; Wood-Baker R; Walters EH | |
2012 | Soltani A, Sohal SS, Reid D, Weston S, Wood-Baker R, et al., 'Vessel-associated transforming growth factor-beta1 (TGF-β 1) is increased in the bronchial reticular basement membrane in COPD and normal smokers', PLoS One, 7, (6) Article e39736. ISSN 1932-6203 (2012) [Refereed Article] DOI: 10.1371/journal.pone.0039736 [eCite] [Details] Citations: Scopus - 38Web of Science - 18 Co-authors: Soltani A; Reid D; Weston S; Wood-Baker R; Walters EH | |
2012 | Soltani A, Wood-Baker R, Sohal SS, Muller HK, Reid D, et al., 'Reticular basement membrane vessels are increased in COPD bronchial mucosa by both factor VIII and collagen IV immunostaining and are hyperpermeable', Journal of Allergy Article 958383. ISSN 1687-9791 (2012) [Refereed Article] DOI: 10.1155/2012/958383 [eCite] [Details] Co-authors: Soltani A; Wood-Baker R; Muller HK; Reid D; Walters EH | |
2011 | Sohal SS, Reid D, Soltani A, Ward C, Weston S, et al., 'Evaluation of epithelial mesenchymal transition in patients with chronic obstructive pulmonary disease', Respiratory Research , 12 Article 130. ISSN 1465-993X (2011) [Refereed Article] DOI: 10.1186/1465-9921-12-130 [eCite] [Details] Citations: Scopus - 102 Co-authors: Reid D; Soltani A; Weston S; Muller HK; Wood-Baker R; Walters EH | |
2010 | Sohal SS, Reid D, Soltani A, Ward C, Weston S, et al., 'Reticular basement membrane fragmentation and potential epithelial mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary disease ', Respirology, 15, (6) pp. 930-938. ISSN 1323-7799 (2010) [Refereed Article] DOI: 10.1111/j.1440-1843.2010.01808.x [eCite] [Details] Citations: Scopus - 135Web of Science - 132 Co-authors: Reid D; Soltani A; Weston S; Muller HK; Wood-Baker R; Walters EH | |
2010 | Soltani A, Reid DW, Sohal SS, Wood-Baker R, Weston S, et al., 'Basement membrane and vascular remodelling in smokers and chronic obstructive pulmonary disease: a cross-sectional study ', Respiratory Research, 11, (105) EJ ISSN 1465-993X (2010) [Refereed Article] DOI: 10.1186/1465-9921-11-105 [eCite] [Details] Citations: Scopus - 66Web of Science - 57 Co-authors: Soltani A; Reid DW; Wood-Baker R; Weston S; Muller HK; Walters EH |
Chapter in Book
(2 outputs)Year | Citation | Altmetrics |
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2015 | Eapen MS, Shukla SD, Mahmood MQ, McAlinden-Volkovickas KD, Eri RD, et al., 'Role of corticosteroids in chronic obstructive pulmonary disease (COPD)', Corticosteroids and Steroid Therapy: New Research, Nova Science Publishers, C Adkins (ed), United Kingdom, pp. 1-40. ISBN 978-1634823081 (2015) [Research Book Chapter] Co-authors: Eapen MS; Shukla SD; Mahmood MQ; McAlinden-Volkovickas KD; Eri RD; Walters EH | |
2013 | Sohal SS, Soltani A, Weston S, Wood-Baker R, Walters H, 'Intermediate filament vimentin and potential role in epithelial mesenchymal transition (EMT)', Vimentin Concepts and Molecular Mechanisms, Nova Science Publishers, RA de Mello (ed), New York, pp. 37-61. ISBN 978-1-62417-359-2 (2013) [Research Book Chapter] Co-authors: Soltani A; Weston S; Wood-Baker R; Walters H |
Review
(6 outputs)Year | Citation | Altmetrics |
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2019 | Eapen MS, McAlinden KD, Myers S, Lu W, Sohal SS, 'microRNAs are key regulators in chronic lung disease: exploring the vital link between disease progression and lung cancer', Journal of Clinical Medicine, 8, (11) pp. 1-6. ISSN 2077-0383 (2019) [Review Several Works] DOI: 10.3390/jcm8111986 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 Co-authors: Eapen MS; McAlinden KD; Myers S; Lu W | |
2019 | Eapen MS, Sharma P, Sohal SS, 'Mitochondrial dysfunction in macrophages: a key to defective bacterial phagocytosis in COPD', The European Respiratory Journal, 54, (4) pp. 1-4. ISSN 0903-1936 (2019) [Review Several Works] DOI: 10.1183/13993003.01641-2019 [eCite] [Details] Citations: Scopus - 15Web of Science - 16 Co-authors: Eapen MS | |
2017 | Eapen MS, Myers S, Walters EH, Sohal SS, 'Airway inflammation in chronic obstructive pulmonary disease (COPD): a true paradox', Expert Review of Respiratory Medicine, 11, (10) pp. 827-839. ISSN 1747-6348 (2017) [Substantial Review] DOI: 10.1080/17476348.2017.1360769 [eCite] [Details] Citations: Scopus - 84Web of Science - 1 Co-authors: Eapen MS; Myers S; Walters EH | |
2017 | Myers S, Shastri M, Adulcikas JA, Sohal SS, Norouzi S, 'Zinc and gastrointestinal disorders: a role for the zinc transporters Zips and ZnTs', Current Pharmaceutical Design, 23, (16) pp. 2328-2332. ISSN 1381-6128 (2017) [Review Several Works] DOI: 10.2174/1381612823666170124115850 [eCite] [Details] Citations: Scopus - 10Web of Science - 10 Co-authors: Myers S; Shastri M; Adulcikas JA; Norouzi S | |
2013 | Sohal SS, Ward C, Danial W, Wood-Baker R, Walters EH, 'Recent advance in understanding inflammation and remodelling in the airways in COPD', Expert Review of Respiratory Medicine, 7, (3) pp. 275-288. ISSN 1747-6348 (2013) [Substantial Review] DOI: 10.1586/ers.13.26 [eCite] [Details] Citations: Scopus - 72Web of Science - 71 Co-authors: Ward C; Danial W; Wood-Baker R; Walters EH | |
2013 | Soltani A, Sohal SS, Reid D, Wood-Baker R, Walters EH, 'Airway Remodeling in Chronic Obstructive Pulmonary Disease (COPD), a Review', Annals of Respiratory Medicine pp. Epub. (2013) [Review Several Works] Co-authors: Soltani A; Reid D; Wood-Baker R; Walters EH |
Conference Publication
(29 outputs)Year | Citation | Altmetrics |
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2016 | Perera AP, Ranson N, Sohal SS, Eri RD, 'Major Role of NLRP3 Inflammasome in Colitis Progression', International Congress of Immunology (ICI), 21 - 26 August, Melbourne, Australia (2016) [Conference Extract] Co-authors: Perera AP; Ranson N; Eri RD | |
2013 | Courtney J, Sharma C, Spafford PL, Sohal SS, Walters EH, 'Epithelial to mesenchymal transition in cultured cells: a potential in vitro model of COPD', Thoracic Society of Australia and New Zealand, Respirology 18 (Suppl 2), Darwin, pp. 58. (2013) [Conference Extract] Co-authors: Courtney J; Sharma C; Spafford PL; Walters EH | |
2013 | Danial W, Sohal SS, Hardikar A, Hunter C, Wood-Baker R, et al., 'Potential epithelial mesenchymal transition (EMT) in the small airways of lung cancer patients', Abstracts of the Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2013 Annual Scientific Meetings, 22-27 March 2013, Darwin, pp. 19-19. (2013) [Conference Extract] Co-authors: Danial W; Wood-Baker R; Walters EH | |
2013 | Shukla SD, Sohal SS, Reid DW, Grigg J, Walters EH, 'Platelet activating factor receptor (PAFr) expression is increased in airways of COPD patients but is not attenuated by inhaled corticosteroids', European Respiratory Society Annual Congress, 7-11 Sept, Barcelona, Spain (2013) [Conference Extract] Co-authors: Shukla SD; Reid DW; Walters EH | |
2013 | Sohal SS, Danial W, Hardikar AA, Hunter CJ, Muller HK, et al., 'Epithelial mesenchymal transition (EMT) in the small and large airways of lung cancer patients undergoing thoracotomy', European Respiratory Society Annual Congress, 7-11 Sept, Barcelona, Spain (2013) [Conference Extract] Co-authors: Danial W; Hardikar AA; Hunter CJ; Muller HK; Wood-Baker R; Walters EH | |
2013 | Sohal SS, Danial W, Hardikar AA, Hunter CJ, Ward Chris, et al., 'Epithelial mesenchymal transition (EMT) in small and large airways of smokers: potential role in both airway fibrosis and cancer', The 8th International Young Investigators' Meeting (YIM) on Airway Smooth Muscle and Fibroblast Biology, Groningen, the Netherlands (2013) [Conference Extract] Co-authors: Danial W; Hardikar AA; Hunter CJ; Ward Chris; Muller HK; Wood-Baker R; Walters EH | |
2013 | Sohal SS, Reid DW, Soltani Abhari A, Weston S, Muller HK, et al., 'Airway histone deacetylase-2 increases after smoking cessation, but is not affected by inhaled corticosteroids in Chronic Obstructive Pulmonary Disease (COPD): A randomized controlled trial', American Thoracic Society (ATS) (2013) [Conference Extract] Co-authors: Reid DW; Soltani Abhari A; Weston S; Muller HK; Wood-Baker R; Walters EH | |
2013 | Sohal SS, Soltani Abhari A, Reid DW, Ward Chris, Muller HK, et al., 'Epithelial mesenchymal transition (EMT) in large airways is attenuated by inhaled fluticasone propionate (FP) in COPD: a randomized controlled trial', The 8th International Young Investigators' Meeting (YIM) on Airway Smooth Muscle and Fibroblast Biology, Groningen, The Netherlands (2013) [Conference Extract] Co-authors: Soltani Abhari A; Reid DW; Ward Chris; Muller HK; Wood-Baker R; Walters EH | |
2013 | Sohal SS, Soltani Abhari A, Reid DW, Wood-Baker R, Walters EH, 'Inhaled fluticasone propionate (FP) restores angiogenesis in the airway lamina propria of current smokers with COPD: a randomized controlled trial', European Respiratory Society Annual Congress, 7-11 Sept, Barcelona, Spain (2013) [Conference Extract] Co-authors: Soltani Abhari A; Reid DW; Wood-Baker R; Walters EH | |
2013 | Sohal SS, Tan D, Muller HK, Reid DW, Walters EH, 'Neutrophil numbers are decreased in bronchial biopsies from patients with COPD', European Respiratory Society Annual Congress, 7-11 Sept, Barcelona, Spain (2013) [Conference Extract] Co-authors: Tan D; Muller HK; Reid DW; Walters EH | |
2013 | Soltani Abhari A, Sohal SS, Reid DW, Muller HK, Weston S, et al., 'Inhaled corticosteroids is effective on only some aspects of bronchial vascular remodelling in COPD', Thoracic Society of Australia and New Zealand, Respirology 18 (Suppl 2), Darwin, pp. 58. (2013) [Conference Extract] Co-authors: Soltani Abhari A; Reid DW; Muller HK; Weston S; Wood-Baker R; Walters EH | |
2012 | Sohal SS, Grigg J, Mushtaq N, Reid DW, Weston S, et al., 'Platelet activating factor receptor (PAFR) expression increases in airways of current smokers', Respirology, 17 (Supp 1), pp. 31. (2012) [Conference Extract] Co-authors: Reid DW; Weston S; Muller HK; Wood-Baker R; Walters EH | |
2012 | Sohal SS, Reid DW, Soltani A, Ward C, Weston S, et al., 'Fluticasone propionate attenuates epithelial mesenchymal transition (EMT) in COPD', Respirology, 17 (Supp 1), pp. 25. (2012) [Conference Extract] Co-authors: Reid DW; Soltani A; Weston S; Muller HK; Wood-Baker R; Walters EH | |
2012 | Sohal SS, Reid DW, Soltani Abhari A, Ward S, Weston S, et al., 'Inhaled corticosteroids (ICS) attenuate epithelial mesenchymal transition (EMT) in chronic obstructive pulmonary disease (COPD) - implications for lung cancer prophylaxis', Journal of Thoracic Oncology 7 (9, Suppl 3), September, Adelaide, pp. S183. (2012) [Conference Extract] Co-authors: Reid DW; Soltani Abhari A; Weston S; Muller HK; Wood-Baker R; Walters EH | |
2012 | Sohal SS, Soltani Abhari A, Reid DW, Ward S, Weston S, et al., 'Inhaled corticosteroids (ICS) attenuates epithelial mesenchymal transition (EMT) in COPD: a key to understanding long term benefits', European Respitatory Journal 39 (Suppl 56), 1-5 September, Vienna, pp. 259S. (2012) [Conference Extract] Co-authors: Soltani Abhari A; Reid DW; Weston S; Muller HK; Wood-Baker R; Walters EH | |
2012 | Sohal SS, Soltani Abhari A, Reid DW, Ward S, Weston S, et al., 'Transforming growth factor - beta 1 (TGF-β 1) expression is related to reticular basement membrane (Rbm) hypervascularity in smokers and COPD', European Respitatory Journal 39 (Suppl 56), 1-5 September, Vienna, pp. 130S. (2012) [Conference Extract] Co-authors: Soltani Abhari A; Reid DW; Weston S; Muller HK; Wood-Baker R; Walters EH | |
2012 | Sohal SS, Soltani Abhari A, Reid DW, Ward S, Weston S, et al., 'Epithelial mesenchymal transition (EMT) in chronic obstructive pulmonary disease (COPD) airways is attenuated by inhaled corticosteroids (ICS)', Thorax 67 (Suppl 2), December, pp. A43. (2012) [Conference Extract] Co-authors: Soltani Abhari A; Reid DW; Weston S; Muller HK; Wood-Baker R; Walters EH | |
2012 | Soltani A, Sohal SS, Reid DW, Weston S, Wood-Baker R, et al., 'Vessel-associated transforming growth factor-Beta1 (TGF-β1) expression is increased in COPD airway', Respirology, 17 (Supp 1), pp. 60. (2012) [Conference Extract] Co-authors: Soltani A; Reid DW; Weston S; Wood-Baker R; Walters EH | |
2011 | Sohal SS, Mudway IS, Weston S, Grigg J, Walters H, 'Enhanced platelet activating factor receptor (PAFR) expression in smoker airways', European Respiratory Journal 38 (Supplement 55), 24-28 September 2011, Amsterdam, The Netherlands, pp. 625s. (2011) [Conference Extract] Co-authors: Weston S; Walters H | |
2011 | Sohal SS, Reid DW, Soltani A, Ward C, Weston S, et al., 'Epithelial mesenchymal transition (EMT) in patients with chronic obstructive disease (COPD)', The Thoracic Society of Australia & New Zealand Annual Scientific Meeting, April, Perth, Australia (2011) [Conference Extract] Co-authors: Reid DW; Soltani A; Weston S; Muller HK; Wood-Baker R; Walters EH | |
2011 | Soltani A, Reid D, Sohal SS, Weston S, Muller HK, et al., 'Comparing factor VIII with collagen IV for immuno-staining of vessels', The Thoracic Society of Australia & New Zealand Annual Scientific Meeting, April, Perth, Australia (2011) [Conference Extract] Co-authors: Soltani A; Reid D; Weston S; Muller HK; Wood-Baker R; Walters EH | |
2010 | Sohal SS, Reid D, Soltani A, Weston S, Muller HK, et al., 'Smoking cessation but not inhaled corticosteroids (ICS) can increase histone deacetylase 2 (HDAC2)] in COPD ', The European Respiratory Journal , pp. 785s. (2010) [Conference Extract] Co-authors: Reid D; Soltani A; Weston S; Muller HK; Wood-Baker R; Walters EH | |
2010 | Sohal SS, Reid DW, Soltani A, Ward C, Weston S, et al., 'Smoking has potential to initiate epithelial mesenchymal transition (EMT) in the airway mucosa', Respirology, pp. Vol 15 (Suppl. 1), A11-A40. (2010) [Conference Extract] Co-authors: Reid DW; Soltani A; Weston S; Muller HK; Wood-Baker R; Walters EH | |
2010 | Soltani A, Sohal SS, Reid D, Weston S, Muller HK, et al., 'Airway Angiogenesis And basement Membrane Remodeling In Smokers And Chronic Obstructive pulmonary Disease: cross-sectional And Longitudinal Studies', American Journal of Respiratory and Critical Care Medicine, pp. Vol 181, A3874. (2010) [Conference Extract] Co-authors: Soltani A; Reid D; Weston S; Muller HK; Wood-Baker R; Walters EH | |
2010 | Soltani A, Sohal SS, Reid D, Weston S, Muller HK, et al., 'Basement membrane remodelling in COPD responds to inhaled corticosteroids', The Thoracic Society of Australia & New Zealand Annual Scientific Meeting, April, Brisbane, Australia (2010) [Conference Extract] Co-authors: Soltani A; Reid D; Weston S; Muller HK; Wood-Baker R; Walters EH | |
2009 | Sohal SS, Reid DW, Soltani A, Ward C, Weston S, et al., 'Smoking has potential to initiate basement membrane disruption and epithelial mesenchymal transition in COPD ', European Respiratory Society Annual Congress , September, Vienna, Austria (2009) [Conference Extract] Co-authors: Reid DW; Soltani A; Weston S; Muller HK; Wood-Baker R; Walters EH | |
2009 | Sohal SS, Reid DW, Ward C, Weston S, Wood-Baker R, et al., 'Evidence of epithelial-mesenchymal transition in COPD?', The Thoracic Society of Australia & New Zealand Annual Scientific Meeting, April, Darwin, Australia (2009) [Conference Extract] Co-authors: Reid DW; Ward C; Weston S; Wood-Baker R; Walters EH | |
2009 | Soltani A, Reid D, Sohal SS, Muller HK, Weston S, et al., 'Vascular and basement membrane remodelling in smokers and COPD', European Respiratory Journal , pp. Vol 53 (34). (2009) [Conference Extract] Co-authors: Soltani A; Reid D; Muller HK; Weston S; Wood-Baker R; Walters EH | |
2009 | Soltani A, Sohal SS, Reid D, Muller HK, Weston S, et al., 'Inhaled corticosteroids in airway remodelling in COPD', Thorax, pp. Vol 64 (4). (2009) [Conference Extract] Co-authors: Soltani A; Reid D; Muller HK; Weston S; Wood-Baker R; Walters EH |
Other Public Output
(94 outputs)Year | Citation | Altmetrics |
---|---|---|
2022 | Bittoun R, Sohal S, 'Nicotine Fact Sheet 3: Nicotine and the Lungs', ResearchOnline@Avondale, Avondale University, Australia (2022) [Report Other] | |
2022 | Gaikwad AV, Brook M, Eapen MS, Corte T, Sohal SS, 'Ground-breaking Australian study is a paradigm shift' in understanding lung scarring this Rare Diseases Day', Lung Foundation Australia, online, 28 February 2022 (2022) [Media Interview] Co-authors: Eapen MS | |
2022 | Gaikwad AV, Eapen MS, Sohal SS, 'Respiratory research Holy Grail: EndMT as a therapeutic target in lung fibrosis', The Limbic, Online, 1 March 2022 (2022) [Media Interview] Co-authors: Eapen MS | |
2022 | Sohal SS, 'Airways distinctly different in asthma COPD overlap: Tasmanian study', The Limbic, online, 1 September 2022 (2022) [Media Interview] | |
2022 | Sohal SS, 'World first research underway in Launceston for 'aggressive' lung disease', The Examiner, Tasmania, Australia, 26 March 2022 (2022) [Media Interview] | |
2022 | Sohal SS, 'New study offers hope for people with terminal lung disease', The Examiner, Tasmania, Australia, 7 February 2022 (2022) [Newspaper Article] | |
2022 | Sohal SS, 'Idiopathic Pulmonary Fibrosis Research Breakthrough', Clifford Craig Foundation, online, February 2022 (2022) [Media Interview] | |
2022 | Sohal SS, 'Autopsy finds man most likely died as a result of vaping', ABC News, online, 21 February 2022 (2022) [Media Interview] | |
2022 | Sohal SS, 'University of Tasmania researcher Sukhwinder Sohal on asthma and COPD', The Examiner, Australia, 27 September 2022 (2022) [Newspaper Article] | |
2022 | Sohal SS, 'Transforming the agenda for COPD: A path towards prevention and lifelong lung health - Lung Foundation Australia's Blueprint for Action on Chronic Obstructive Pulmonary Disease (COPD) 2022-2025', Lung Foundation Australia, Australia, pp. 1-63. (2022) [Government or Industry Research] | |
2021 | Brook M, Haug G, Sohal SS, 'Call for nationwide vape ban as concern grows for young people', Lung Foundation Australia, online, 24 August 2021 (2021) [Media Interview] Co-authors: Haug G | |
2021 | Brook M, Sohal SS, 'Toxic and dangerous: The mission to stop Aussie students turning to vapes', EducationHQ News, online, 16 September 2021 (2021) [Media Interview] | |
2021 | Sohal SS, 'Is vaping really safer than smoking? Here's what experts say', MamaMia, Online, 17 June 2021 (2021) [Media Interview] | |
2021 | Sohal SS, 'Changes to legislation around vaping sees varied opinions', The Examiner, Tasmania, Australia, 23 September 2021 (2021) [Media Interview] | |
2021 | Sohal SS, 'Interview with our Researcher', Clifford Craig Foundation, online (2021) [Media Interview] | |
2021 | Sohal SS, 'Dr Sukhwinder Sohal leads Tasmanian research changing the lung cancer trajectory', The Examiner, Tasmania, Australia, 2 July 2021 (2021) [Newspaper Article] | |
2020 | Sohal SS, '3 Questions About the Pathogenesis of COPD', Pulmonology Consultant, online, 22 January 2020 (2020) [Media Interview] | |
2020 | Sohal SS, 'Additional References Related to the Pathogenesis of COPD', PulmonologyConsultant, online, 22 January 2020 (2020) [Media Interview] | |
2020 | Sohal SS, 'University of Tasmania researcher Dr Sukhwinder Singh Sohal says smokers at higher risk from COVID-19', Camden Haven Courier, online, 24 March 2020 (2020) [Media Interview] | |
2020 | Sohal SS, 'Tasmanian research examining safety of e-cigarettes and its consequences amid COVID-19', The Advocate, Tasmania, Australia, 26 November 2020 (2020) [Media Interview] | |
2020 | Sohal SS, Barnsley K, 'University of Tasmania researcher Dr Sukhwinder Singh Sohal says smokers at higher risk from COVID-19', Forbes Advocate, online, 24 March 2020 (2020) [Media Interview] Co-authors: Barnsley K | |
2020 | Sohal SS, Barnsley K, 'University of Tasmania researcher Dr Sukhwinder Singh Sohal says smokers at higher risk from COVID-19', Queensland Country Life, online, 24 March 2020 (2020) [Media Interview] Co-authors: Barnsley K | |
2019 | Sohal SS, 'Evaluation of new therapeutic targets in idiopathic pulmonary fibrosis (IPF): insights from Australian IPF registry tissue analysis', Craig Clifford Foundation News Bulletin, Launceston, Tasmania (2019) [Magazine Article] | |
2019 | Sohal SS, 'Prevalence of asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS) in north-west Tasmanian population: understanding and translation to early therapy', Craig Clifford Foundation News Bulletin, Launceston, Tasmania (2019) [Magazine Article] | |
2019 | Sohal SS, 'IQOS can be as harmful as cigarettes. But eCig can also be dangerous when used at medium and high concentrations. The study, for now only in vitro, in the journal of the European Respiratory Society', Science and Drugs: newspaper of online health information, Quotidianosanita.it, Italy, 20 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'New type of E-Cig as bad as regular cigarette for your lungs', Healthline, Healthline Media, United States, 15 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'Heated tobacco is no less harmful than regular cigarettes', Science and Life Russia, ANO Editorial Board, Russia, 13 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'No type of smoking is safe: cigarettes, heated tobacco, vaping all', Metro, Associated Newspapers Limited, United Kingdom, 12 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'Heated tobacco devices equally harmful as e-cigarettes, smoking: Study', The Indian Express, Indian Express Group, India, 12 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'Tasmania-led study suggests e-cigarettes and heat-not-burn products are as equally toxic to lungs', The Examiner, Fairfax Media Limited, Australia, 15 Febuary 2019 (2019) [Newspaper Article] | |
2019 | Sohal SS, 'Harmful smoke heaters for the lungs', Ta Nea, Greece, 11 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'New heated tobacco device is as toxic as vaping and traditional cigarettes', The Medical News, AZoNetwork, United Kingdom, 11 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'New heated tobacco device causes same damage to lung cells as e-cigs and smoking', Medical Xpress, Science X, United Kingdom, 11 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'Heated tobacco devices equally harmful as e-cigarettes, smoking: Study', Business Standard, Business Standard Private Limited, India, 11 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'Tabacco heater is no healthier than a cigarette', Wissenschaft Aktuell, GLS Gemeinschaftsbank Bochum, Germany, 10 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'New heated tobacco device causes same damage to lung cells as e-cigs and smoking', EurekAlert!, American Association for the Advancement of Science, United States, 10 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'Heated tobacco products cause similar cell inflammation to combustible cigarettes', MD Magazine, MJH Healthcare Holdings, United States, 19 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'Electronic smoking as dangerous as the real thing', University of Tasmania News, University of Tasmania, Australia, 15 Febuary 2019 (2019) [Internal Newsletter] | |
2019 | Sohal SS, 'Launceston researcher's key finding on fatal lung disease', The Examiner, Fairfax Media Limited, Australia, 1 April 2019 (2019) [Newspaper Article] | |
2019 | Sohal SS, 'Launceston-based University of Tasmania study debunks heat-not-burn tobacco myth', The Mercury, News Corp Australia, Australia, 14 Febuary 2019 (2019) [Newspaper Article] | |
2019 | Sohal SS, 'Tasmanian tobacco researchers issue dire warnings on danger of vaping', The Mercury, News Corp Australia, Australia, 18 Febuary 2019 (2019) [Newspaper Article] | |
2019 | Sohal SS, 'Talking point: Let's not get burnt all over again', The Mercury, Australia, 21 Febuary 2019 (2019) [Newspaper Article] | |
2019 | Sohal SS, 'Tasmanian-led study suggests e-cigarettes and heat-not-burn products are as equally toxic to lungs', Clifford Craig Foundation News Bulletin, Clifford Craig Foundation, Australia, 8 March 2019 (2019) [Internal Newsletter] | |
2019 | Sohal SS, 'Launceston researcher's key finding on fatal lung disease', Clifford Craig Foundation News Bulletin, Clifford Craig Foundation, Australia, 4 April 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'All nicotine devices as toxic for lungs as cigarettes are', MediBulletin, India, 11 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'Vaping: Any kind of smoking is 'toxic'', Cover, Incisive Business Media Limited, United Kingdom, 15 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'Heat-not-burn cigarettes are not a good alternative - they are still terrible for your lungs', Technology.org, United States, 24 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'How safe are heat-not-burn smoking devices?', European Medical Group, United Kingdom, 5 March 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'New safer' e-cigarettes are JUST as dangerous for your lungs as vaping and smoking'', The Sun, News Group Newspapers Limited, United Kingdom, 11 Febuary 2019 (2019) [Newspaper Article] | |
2019 | Sohal SS, 'Cigarettes, vaping and heated tobacco 'cause serious lung damage'', The Star, Kenya, 12 Febuary 2019 (2019) [Newspaper Article] | |
2019 | Sohal SS, 'Tasmania-led study suggests e-cigarettes and heat-not-burn products are as equally toxic to lungs', The Advocate, Fairfax Media Limited, Australia, 12 February 2019 (2019) [Newspaper Article] | |
2019 | Sohal SS, 'Launceston researcher's key finding on fatal lung disease', The Advocate, Fairfax Media Limited, Australia, 1 April 2019 (2019) [Newspaper Article] | |
2019 | Sohal SS, 'ICAM-1 and other potential biomarkers for IPF flagged', The Limbic Respiratory, thelimbic.com, Australia, 8 April 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'New heated tobacco device causes the same damage to lung cells as traditional cigarettes and e-cigarettes', European Respiratory Society, United Kingdom, 11 February 2019 (2019) [Internal Newsletter] | |
2019 | Sohal SS, 'Vaping could be more dangerous than you think', Wellnessdaily, Momentum Media Group, Australia, 25 March 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, 'Doctors at odds over value of vaping, as study finds it's just as harmful as cigarettes', ABC News online, ABC, 5 November (2019) [Media Interview] | |
2019 | Sohal SS, 'UTAS study finds vaping just as harmful as cigarettes', www.tasmaniatalks.com.au, Australia, 7 November (2019) [Newspaper Article] | |
2019 | Sohal SS, 'New registry to offer greater insight into causes and treatments for lung cancer', UTAS Newsletter, University of Tasmania, Australia, 24 October 2019 (2019) [Internal Newsletter] | |
2019 | Sohal SS, Myers S, Tristram S, Lucciano S, 'Editorial: Clifford Craig Foundation researchers', The Examiner, Australia, October 25 (2019) [Newspaper Article] Co-authors: Myers S; Tristram S | |
2019 | Sohal SS, Sharma P, 'Heated tobacco device poses same danger to lungs as cigarettes, vaping', Breitbart News, United States, 11 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, Sharma P, 'New heated tobacco device causes same damage to lung cells as e-cigs and smoking, study finds', Long Room News, United States of America, 11 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, Sharma P, 'Heated tobacco device poses same danger to lungs as cigarettes, vaping', UPI, United Press International, United States, 11 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, Sharma P, 'New heated tobacco device causes same damage to lung cells as e-cigs and smoking, study finds', ScienceDaily, ScienceDaily, United States, 11 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, Sharma P, 'Is any smoking safe? Cigarettes, vaping and heated tobacco ALL cause serious lung damage'', Daily Mail Australia, Associated Newspapers Ltd, Australia, 11 Febuary 2019 (2019) [Newspaper Article] | |
2019 | Sohal SS, Sharma P, 'Health: Heated tobacco is as harmful as cigarettes', Pourquoi docteur, France, 11 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, Sharma P, 'Research on smoke heating appliances - Papastratos' answer', skai.gr, Skai Group, Greece, 11 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, Sharma P, 'Here comes novel device equally harmful as traditional smoking, e-cigarettes', New Kerala, India, 11 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, Sharma P, 'New heated tobacco devices no lesser in causing harm to lungs', Medindia, Medindia, India, 11 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, Sharma P, 'Here comes novel device equally harmful as traditional smoking, e-cigarettes', The Pioneer, CMYK Printech Limited, India, 11 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, Sharma P, 'Here comes novel device equally harmful as traditional smoking, e-cigarettes', Business Standard, Business Standard Private Limited, India, 11 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, Sharma P, 'Here comes novel device equally harmful as traditional smoking, e-cigarettes - Canindia News', Canindia, World Media Corp Inc, Canada, 11 February 2019 (2019) [Magazine Article] | |
2019 | Sohal SS, Sharma P, 'Vaping and traditional cigarettes: both damaging to the lungs, research says', New Zealand Herald, NZME. Publishing Limited, New Zealand, 11 Febuary 2019 (2019) [Newspaper Article] | |
2019 | Sohal SS, Sharma P, 'New heated tobacco device causes same damage to lung cells as e-cigs and smoking', European Lung Foundation, United Kingdom, 11 Febuary 2019 (2019) [Internal Newsletter] | |
2018 | Schmidt M, Cannell JA, Flanagan K, Sohal SS, Mulford J, et al., ''Champions' of research', The Examiner, Australia, 2 November 2018 (2018) [Newspaper Article] Co-authors: Schmidt M; Cannell JA; Flanagan K; Mulford J; Myers SA | |
2018 | Sohal S, 'Breathing life into local research', Quest Quarterly Newsletter, Royal Hobart Hospital Research Foundation, Australia, Spring edition, p. 1. (2018) [Magazine Article] | |
2018 | Sohal SS, 'Epithelial Mesenchymal Transition (EMT) in the lungs and airways in Idiopathic Pulmonary Fibrosis (IPF)', Craig Clifford Foundation News Bulletin (2018) [Magazine Article] | |
2018 | Sohal SS, 'UTAS recognised as centre for idiopathic pulmonary fibrosis research', The Examiner, online, 6 March 2018 (2018) [Newspaper Article] | |
2018 | Sohal SS, 'School of Health Sciences recognised as national centre for lung disease research', UTAS Student News, 2 March 2018 (2018) [Internal Newsletter] | |
2018 | Sohal SS, 'School of Health Sciences researcher recognised with award', UTAS Communications and Media News, online, 26 April 2018 (2018) [Internal Newsletter] | |
2018 | Sohal SS, 'UTAS recognised as centre for idiopathic pulmonary fibrosis research', North West Star, 6 March 2018 (2018) [Newspaper Article] | |
2018 | Sohal SS, 'Tasmanian Dr Sukhwinder Sohal to research asthma-COPD overlap syndrome in state's North West', The Examiner, Australia, 22 November 2018 (2018) [Newspaper Article] | |
2018 | Sohal SS, 'Disease process examined', The Advocate, Australia, 24 November 2018 (2018) [Newspaper Article] | |
2018 | Sohal SS, Wark P, McKeogh Z, Worsnop C, 'Chronic Obstructive Pulmonary Disease (COPD): Activities and Highlights in 2017', The Thoracic Society of Australia and New Zealand (TSANZ) Annual Report, The Thoracic Society of Australia and New Zealand (TSANZ), Australia, 2017, p. 23. (2018) [Magazine Article] | |
2017 | Sohal SS, 'Smoking is not directly tied to airway inflammation in COPD', Consultant 360, online (2017) [Media Interview] | |
2017 | Sohal SS, 'New study challenges description of airway inflammation in smokers and COPD patients', http://newsroom.wiley.com, online, 22 March, 2017 (2017) [Media Interview] | |
2017 | Sohal SS, 'International recognition for University researcher's work on lung disease', http://www.utas.edu.au/health/latest-news (2017) [Award] | |
2017 | Sohal SS, 'Scholarship Award: National Emphysema Foundation Honouring Claude Lenfant by the American Thoracic Society (ATS)' (2017) [Award] | |
2017 | Sohal SS, 'Launceston doctor studying idiopathic pulmonary fibrosis, a fatal lung disease', The Examiner (2017) [Newspaper Article] | |
2016 | Sohal SS, 'UTAS lung cancer research breakthrough', The Mercury, online, 13 August, 2016 (2016) [Media Interview] | |
2016 | Sohal SS, 'University of Tasmania researcher recognised', The Examiner, 29 June 2016 (2016) [Newspaper Article] | |
2016 | Sohal SS, 'Department of Industry, Innovation and Science Innovative Science and Technology Award 2016', Australian Government (2016) [Award] | |
2015 | Sohal SS, 'A lethal epithelial transition in COPD', http://www.internationalinnovation.com/, International Innovation (2015) [Media Interview] | |
2013 | Sohal SS, '2013 Young Scientist of the Year', European Respiratory Society (ERS) (2013) [Award] | |
2013 | Sohal SS, 'Global honour for UTAS researcher', http://www.brandtasmania.com, 13 August, 2013, 141 (2013) [Award] |
Grants & Funding
Funding Summary
Number of grants
33
Total funding
Projects
- Description
- This project driven by clinicians concerns regarding delays experienced by lung cancer patients. Tasmanian lung cancer patients experience some of the worst outcomes nationally. Timely diagnosis and treatment can improve survival and quality of life. To address this, we will investigate patient and service delivery factors that influence outcomes with the aim of co-designing and piloting strategies to improve the outcomes for Tasmanians diagnosed with lung cancer
- Funding
- Royal Hobart Hospital Research Foundation ($449,997)
- Scheme
- Grant-Major Project
- Administered By
- University of Tasmania
- Research Team
- Cox IA; Harkness N; Van Dam PJ; Palmer AJ; de Graaff B; Otahal P; Hensher M; Grundy R; Ball E; Black A; Witherden E; Sohal SS
- Period
- 2024 - 2026
- Description
- LTI-03 is a peptide representing 7 amino acids in the cavelolin-1 scaffolding domain (CSD) that is being developed as a novel therapy for idiopathic pulmonary fibrosis (IPF). IPF is a progressive, fatal, age-associated lung disease with a median survival from diagnosis of 2-4 years. The adjusted incidence and prevalence of IPF is estimated to be in the range of 0.091.30 and 0.334.51 per 10,000 persons, respectively per year in Europe and North America. According to these prevalence estimates, IPF remains a rare disease. The pathogenesis of IPF is characterized by apoptosis and senescence of alveolar epithelial type 2 cells (AEC2), proliferation and accumulation of activated myofibroblasts, deposition of extracellular matrix, and fibrosis, resulting in progressive dyspnea and loss of lung function. IPF is rare in patients younger than 50 years old with a median age at diagnosis of approximately 65 years. Most patients with IPF present with advanced disease. Two FDA-approved anti-fibrotic drugs, Nintedanib and Pirfenidone, slow the decline of lung function as measured by forced vital capacity and showed modest efficacy in reducing acute respiratory exacerbations and hospitalization for respiratory events. Although both drugs are approved for marketing in the United States and the European Union; unfortunately, neither drug is curative and provide only modest clinical benefit in IPF patients. Furthermore, both drugs are poorly tolerated leading to frequent discontinuations. The limited known benefits of these drugs and poor tolerability raise the possibility that more effective pharmacotherapy for IPF and related interstitial lung diseases can be identified.
- Funding
- Lung Therapeutics, Inc. ($165,015)
- Scheme
- Contract Research
- Administered By
- University of Tasmania
- Research Team
- Sohal SS
- Period
- 2023 - 2024
- Description
- IPF is a relatively common and devastating lung disease that occurs in late age and elderly people, with an average survival of just 3 years. Our major goal through this project is to provide novel understanding of the early pathology of IPF and its driving mechanisms. Understanding the mechanisms in early IPF disease will have huge therapeutic implications. It will lead to earlier and more accurate diagnosis and allow for the monitoring of response to therapy at its earliest stages. This study will provide significant understanding and contribution of EndMT towards pulmonary hypertension and fibrogenesis of IPF. Our prime focus will be to target EndMT, which we believe is one of the fundamental pathological mechanisms that leads to increase in myofibroblasts and fibrotic destruction of the lung tissue. We would also compare the findings from the current study to other chronic respiratory diseases such as COPD to understand differences in pathology of different disease of same organ.
- Funding
- Clifford Craig Foundation ($72,726)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Sohal SS; Chia C; Haug G; Larby J; Eapen MS
- Period
- 2022 - 2023
- Description
- The wellbeing of women during pregnancy affects the health of the unborn baby. This can also have lasting effects, for example abnormal lung function tests in early life persist into adulthood and could result in COPD in later life. Pregnant mothers in NW Tasmania are more commonly overweight and obese, and a higher proportion of pregnant women smoke compared to the rest of Tasmania and Australia. Both these problems during pregnancy could result in problems during pregnancy, birth complications, medical problems in early life, and ultimately affect chronic diseases in adulthood. This led to two current research projects to address both excessive weight gain and smoking during pregnancy. The first is - 14 - CCF Application for Research Grant aimed at minimising excessive weight gain during pregnancy and the other is to monitor carbon monoxide during pregnancy, ultimately hoping to reduce smoking during pregnancy. This study proposes to look at how these interventions in pregnancy will impact the health of the babies. If found to be successful, these low-cost interventions could lead to immediate improved health outcomes, affect chronic disease in later life and it could easily be introduced in similar regional and socio-economically disadvantaged areas of the world.
- Funding
- Clifford Craig Foundation ($72,661)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Weber HC; Prior SJ; Luccisano S; Robertson IK; Gleeson M; Sohal SS; Young S
- Year
- 2022
- Description
- The damaging health effects of active and second-hand cigarette smoking are well documented. Tobacco smoke exposure is the primary cause of COPD and lung cancer. However, the prevalence of tobacco smoking is on the gradual decline. In response to this, the tobacco industry is currently changing strategies, shifting the focus from tobacco cigarettes and promoting the safer alternative in e-cigarettes. e-cigarettes still deliver nicotine and the number of dual users (traditional cigarettes and e-cigarettes) is alarming.We aim to evaluate the effects of e-cigarettes on:1.Promoting airway inflammation.2.Airway remodelling changes.3.Increasing respiratory infections.
- Funding
- Clifford Craig Foundation ($80,000)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Sohal SS; Chia C; Larby J; Haug G; Barnsley KI; Tristram SG; Myers SA; Eapen MS; Lu W; Weber HC
- Period
- 2021 - 2022
- Description
- The aim of this project is to detect early lung function changes in smokers to change disease trajectory.We will achieve this by measuring the following variables:1.Spirometry (the current reference measure of lung function based on performance of the large airways); 2. Forced Oscillation Technique(FOT; a measure of small airway function); and, 3. Blood biomarkers of respiratory inflammation and degradation of pulmonaryextracellular matrix, in three groups of individuals: 1. patients with chronic obstructive respiratory disease (COPD), 2. smokers with normallung function; and, 3. healthy individuals who have never smoked in order to find the relationship between the measures of spirometry,FOT and biomarkers across the sample population.
- Funding
- Clifford Craig Foundation ($15,794)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Williams AD; Sohal SS; Myers SA; Chia C
- Year
- 2021
- Description
- The project will entail the introduction of routine carbon monoxide (CO) screening for all pregnant mothers attendingantenatal clinics in North West Tasmania to identify mothers and babies who are at high risk during pregnancy. An opt-out recruitment method, usedsuccessfully previously, will be used to maximise the participation of pregnant mothers. It is known that a substantial proportion of pregnant mothersunderreport exposure to tobacco smoke, and the under recognition of this and the subsequent lack of referral to a smoking cessation service are likelyto affect the mother's health as well as resulting in lifelong health consequences for the unborn baby.
- Funding
- Department of Health (Cth) ($40,000)
- Scheme
- Contract Research
- Administered By
- University of Tasmania
- Research Team
- Weber HC; Sohal SS; Frandsen M; Gleeson M
- Year
- 2020
- Description
- Insulin resistance (IR) is a disorder where cells do not respond to insulin and therefore glucose and fat metabolism are compromised. IR is present before, and contributes to, the development of type 2 diabetes (T2D) and several pathological conditions and complications including blindness, neurodegenerative disease, heart disease, kidney failure, amputations and reduced quality of life. Despite extensive research, there is challenging uncertainty of the molecular mechanisms of IR. Recently, we have published a role for zinc and the zinc transporter protein ZIP7 in control of glucose metabolism in IR skeletal muscle. However, a major 'gap' in this work is the lack of understanding of how ZIP7 is regulated in IR. Delineating how ZIP7 is regulated is highly significant to understand how this zinc transporter might be targeted pharmacologically and lead to clinical interventions for the treatment of IR. Accordingly, we hypothesise that ZIP7 modulates cellular pathways that control glucose metabolism in IR skeletal muscle and is therefore amendable to clinical intervention for the treatment of IR.
- Funding
- Clifford Craig Foundation ($17,607)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Myers SA; Sohal SS; Henstridge DC; Mulford J; Fettke G
- Year
- 2020
- Description
- Despite the health initiatives in tobacco control, Tasmania continues to have the second highest smoking rates in the nations after Northern Territory. According to the Cancer Council Tasmania, current smoking rates for the state is 18.9% compared to national current smoking rate of 16.0%. Due to high smoking rates lung cancer is now one of the major killers in Tasmania. Smoking also leads to chronic obstructive pulmonary disease (COPD) which is a major risk factor for lung cancer. Nearly 70% of lung cancer occurs in early COPD. So, in Tasmania we have high prevalence of lung cancer but also a high-risk current smoking population with or without COPD. According to Lung Foundation Australia, lung cancer currently is Australia's biggest cancer killer. It kills more people than breast, prostate and ovarian cancers combined. One Australian dies every hour from lung cancer. Australians diagnosed with lung cancer in 2017 were 12,500 i.e. 34 people per day and it is on an upward trajectory. We aim to establish a Tasmanian Lung Cancer Registry.
- Funding
- Clifford Craig Foundation ($72,727)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Sohal SS; Chia C; Larby J; Haug G; Mabeza G; Weber HC; Young S; Hardikar AA; Eapen MS; Lu W
- Period
- 2020 - 2021
- Description
- We have discovered a strain of a harmless bacterial species that lives in the throats of healthy people that produces a novel substance that inhibits the growth of the respiratory pathogen - Haemophilus influenzae. The study involves an evaluation of the potential of this strain as a respiratory probiotic
- Funding
- Clifford Craig Foundation ($18,150)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Tristram SG; Sohal SS
- Period
- 2020 - 2021
- Description
- LAM is a rare disorder that affects women, especially during their reproductive age, by progressively destroying the lungs leading to complete incapacitation. There have been very few effective therapies available yet, with the highly invasive lung transplantation being the only option available as a possible cure. Although drug treatment are available, they are moderately effective or have variable outcomes and their possible long-term side effects in patients are still unknown. This in part is because many aspects of the underlying pathogenesis remains a mystery and needs urgent deciphering. Interestingly, cells in LAM patients share identical morphological and cellular signatures to other fibrotic disorders such as idiopathic pulmonary fibrosis (IPF), small airway disease (SAD) in smokers and lung cancer. Our experience in these diseases would suggest that epithelial cells could be the possible source of LAM cells. Here, we wish to investigate new paradigm that will take into account some unique features of LAM, which includes the source of cellular heterogeneity, epithelial transformation capabilities and their potential metastasizing factors. We further also hope to develop in-vitro cell culture models with LAM cells that will serve as a useful tool for further investigations into disease pathogenesis and the development of possible new therapeutic targets.
- Funding
- LAM Australia Research Alliance ($30,000)
- Scheme
- Donation - Individual
- Administered By
- University of Tasmania
- Research Team
- Sohal SS; Oliver B
- Period
- 2019 - 2022
- Description
- Almost 70% of lung cancers occur in patients with COPD, but this link is poorly researched. The process of EMT is active in COPD with associated hyper-vascularity. EMT and angiogenesis in the same area has been designated EMT Type-3, which is a recognised dangerous pre-malignant condition. EMT-Type-3 provides a pro-cancer stroma that both stimulates epithelial cancer cell transformation. This study aims to tease out the key drivers of these changes.
- Funding
- Cancer Council of Tasmania ($10,000)
- Scheme
- Grant-Small
- Administered By
- University of Tasmania
- Research Team
- Lu W; Sohal SS
- Year
- 2019
- Description
- The inability to respond sufficiently to insulin gradually erodes our health. Type 2 diabetes (T2D) results from such insulin resistance in peripheral tissues such as skeletal muscle. In fact, skeletal muscle is the major peripheral tissue that accounts for 70-80% of glucose uptake. While there are several theories on how insulin resistance may manifest, the molecular mechanisms are still largely unclear. Given the major impact this disorder has on the health of our communities, there is an urgent need for continued basic science to understand these mechanisms to appropriately design better therapeutics to treat this disorder. Recently, zinc has been highlighted as a critical metal ion implicated in maintaining glucose homeostasis and therefore is a vital target to study its effects on insulin resistance. We have recently published a role for this metal ion in regulating glucose metabolism in skeletal muscle cells through the concomitant action of several cell signalling molecules. However, it is unclear how this is achieved. Accordingly, this study aims to address the molecular mechanisms whereby zinc can contribute to the regulation of glucose metabolism in insulin resistant skeletal muscle.
- Funding
- Clifford Craig Foundation ($21,944)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Myers SA; Sohal SS; Sonda S; Williams AD; Adulcikas JA
- Year
- 2019
- Description
- IPF is a highly destructive lethal disease of the lungs, but with very little information available on the underlying mechanisms. We are going to explore the process of epithelial cell plasticity (or EMT) and a similar process in blood vessel endothelium (Endo-MT). This work will lead to improved diagnosis and treatment of this nasty lung condition. The project brings together well-characterized patients from the Australian IPF registry, blood samples we have collected from them and innovative techniques to reset thinking about the underlying pathological processes active in this illness.
- Funding
- Clifford Craig Foundation ($72,727)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Sohal SS; Walters EH; Myers SA; Geraghty DP; Chia C; Larby J; Haug G; Eapen MS
- Period
- 2019 - 2020
- Description
- Asthma and COPD are typically characterised as separate diseases with different clinical features, pathophysiological mechanisms and strategies for treatment. Some respiratory patients appear to have features of both diseases, i.e. a history of asthma and usually smoking, with marked fixed airflow obstruction, which is termed asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS). Exacerbation rates are also quite high in ACOS patients compared to asthma or COPD alone. There is very little known about the disease and it is difficult to manage clinically because the underlying disease mechanisms and prevalence is poorly understood. There is high prevalence of undiagnosed asthma, COPD and even more for ACOS in the North-West (NW) Tasmanian population, where smoking rates are quite high. People from the low socio-economic population in particular experience considerably greater mortality and morbidity from such respiratory diseases compared to rest of the community. Respiratory lung function lab has now been established in the NW for identification of lung diseases. We now wish to apply for funding with an objective to identify the burden of ACOS in the NW population to inform clinical practice for better management of this ill-understood condition.
- Funding
- Clifford Craig Foundation ($105,868)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Sohal SS; Frandsen M; Ahuja KDK; Beckett JM; Mabeza FG; Weber HC; Young S; Eapen MS
- Period
- 2019 - 2020
- Description
- The M1/M2 phenotype balance has also been especially discussed in the cancer literature as an orchestrator of EMT in driving epithelial malignancies. Such new and translatable insights in COPD are an international priority given the current absence of any significant disease trajectory-modifying drug interventions in clinical practice. Here we continue to focus on EMT in COPD, but especially investigating the role of macrophage-associated cytokines in driving EMT in different patient groups leading to new therapeutic targets.
- Funding
- Rebecca L Cooper Medical Research Foundation ($100,000)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Sohal SS; Geraghty DP; Myers SA
- Period
- 2019 - 2020
- Description
- The results of numerous recent studies indicate that activation of endothelial (vessel) cells and their transition into collagen-producing myo-fibroblasts (EndoMT) is likely to play an important role in the pathogenesis of organ fibrosis in general. We hypothesize the confirmation of active EndoMT in IPF lungs and elucidation of the molecular mechanisms will provide the deep understanding for new therapeutic approaches in IPF.
- Funding
- Lung Foundation Australia ($45,000)
- Scheme
- Scholarship-PhD
- Administered By
- University of Tasmania
- Research Team
- Sohal SS; Moodley Y
- Period
- 2019 - 2021
- Funding
- Rebecca L Cooper Medical Research Foundation ($100,000)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Sharma P; Sohal SS
- Period
- 2019 - 2020
- Description
- The aim of this project to examine the associations with the higher childhood asthma prevalence in North West Tasmania as determined in an earlier study. We plan to confirm this asthma prevalence with objective tests, such as lung function tests. We further which to determine the association of childhood asthma with allergens, environmental factors and prenatal factors.
- Funding
- Clifford Craig Foundation ($83,705)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Weber HC; Sohal SS
- Period
- 2019 - 2022
- Description
- The inability of the body to respond adequately to insulin following a meal has serious consequences on health. Insulin aids in the uptake of glucose into cells, providing the liver with a store of glucose to maintain blood glucose when needed, and as a vital fuel for energy in skeletal muscle. In an insulin-resistant state, cells cannot utilise glucose, which subsequently causes serious medical conditions including obesity, hypertension, cardiovascular disease and type 2 diabetes. Previously, emerging research has shown that zinc and the proteins that transport zinc in cells play a crucial role in activating molecules involved in glucose uptake in skeletal muscle. Recently we have shown that zinc can promote glucose utilisation in the absence of insulin in skeletal muscle. This presents with an opportunity to manipulate zinc metabolism therapeutically to provide an alternative pathway for providing glucose to cells during an insulin-resistant state.
- Funding
- Clifford Craig Foundation ($21,460)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Myers SA; Sohal SS; Fettke G
- Year
- 2018
- Funding
- National Health & Medical Research Council ($830,005)
- Scheme
- Grant-Project
- Administered By
- University of Western Australia
- Research Team
- Moodley Y; Corte T; Knight D; Reynolds P; Walters EH; Glaspole I; Baltic S; Sohal SS; Grainge C
- Period
- 2018 - 2020
- Grant Reference
- 1147776
- Description
- IPF is a highly destructive lethal disease of the lungs, but with very little information available on the underlying mechanisms. We are going to explore the process of epithelial cell plasticity (or EMT) and a similar process in blood vessel endothelium (Endo-MT). This work will lead to improved diagnosis and treatment of this nasty lung condition. The project brings together well-characterized patients from the Australian IPF registry, blood samples we have collected from them and innovative techniques to reset thinking about the underlying pathological processes active in this illness.
- Funding
- Clifford Craig Foundation ($48,354)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Sohal SS; Walters EH; Myers SA; Ahuja KDK; Chia C; Larby J; Haug G; Eapen MS
- Period
- 2018 - 2019
- Description
- Describe your project: This proposal will provide rapid innovative avenues for translational therapies in fundamental aspects of COPD. The fact that we are largely researching therapeutic agents already available and in clinical use, though not for early COPD, adds credibility to our projection of rapid translation to clinical practice in this setting.
- Funding
- Thoracic Society of Australia & New Zealand ($30,000)
- Scheme
- Award - Boehringer Ingelheim COPD Research Award
- Administered By
- University of Tasmania
- Research Team
- Sohal SS
- Year
- 2018
- Description
- Small airway fibrosis is the main contributor to physiological airway obstruction in COPD. The other main airway pathology in COPD is lung cancer; up to 70% of smoking related lung cancer occurs in mild-moderate COPD. EMT may underlie both pathological features; if true this opens up major new therapeutic possibilities. We aim to investigate the effect of pharmacological agents on the EMT in airways of smokers and COPD.
- Funding
- Clifford Craig Foundation ($72,727)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Sohal SS; Chia C; Larby J; Haug G; Noor WD; Myers SA; Eapen MS
- Period
- 2017 - 2018
- Description
- PAFr is a key gateway for infection of the lower respiratory tract in COPD with Streptococcus pneumoniae and Haemophilus influenzae and represents a viable anti-infective therapeutic tar-get in this disease to block progression and acute exacerbations.
- Funding
- Boehringer Ingelheim International GMBH ($50,000)
- Scheme
- Contract Research
- Administered By
- University of Tasmania
- Research Team
- Walters EH; O'Toole RF; Sohal SS
- Year
- 2016
- Description
- This donation is intended to support the work of the 'Breathe Well' NHMRC CRE, based in the School of Medicine. The Centre's NHMRC funding concludes this year. In particular, the donation is to support the completion of PhD projects and fund strategic research involving collaboration between respiratory researchers in the Faculty. This will enable the researchers to seek further NHMRC funding.
- Funding
- Donation via University of Tasmania Foundation ($100,000)
- Scheme
- Donation - Individual
- Administered By
- University of Tasmania
- Research Team
- Canny B; Walters EH; Zosky GR; O'Toole RF; Ferguson SG; Peterson GM; Sohal SS
- Year
- 2016
- Description
- Describe your project: Insulin resistance (IR) is a disorder that is characterised by the failure of cells in the body to respond to insulin and therefore use glucose efficiently as an energy source. Prolonged IR can lead to Type 2 diabetes (T2D), a devastating disease that is intensifying worldwide. T2D is associated with related diseases including heart disease, obesity, mental illness, and cancer. Although IR is well-researched, its molecular mechanisms are still unclear. Recently, studies involving zinc and the proteins that transport zinc in cells (zinc transporters) have been highlighted for their role in regulating genes and proteins involved in disease. Specifically, one zinc transporter designated as Zip7 is involved in regulating zinc in cells and thus preserving cell function. Accordingly, this project aims to understand the molecular mechanisms of Zip7 and how it can be used to reverse IR and could therefore be amendable to treatment options for T2D.
- Funding
- Clifford Craig Foundation ($25,959)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Myers SA; Sohal SS; Fettke G
- Year
- 2016
- Description
- Small airway fibrosis is the main contributor to physiological airway obstruction in COPD. The other main airway pathology in COPD is lung cancer; up to 70% of smoking related lung cancer occurs in mild-moderate COPD. EMT may underlie both pathological features; if true this opens up major new therapeutic possibilities. We aim to investigate EMT in airways of smokers and COPD.
- Funding
- Clifford Craig Foundation ($39,206)
- Scheme
- Grant
- Administered By
- University of Tasmania
- Research Team
- Sohal SS; Chia C; Larby J; Haug G; Eri RD; Myers SA; Noor WD
- Year
- 2016
- Description
- This project will evaluate expression patterns of 30 antibodies across all strains of Devil Facial Tumour from 2005 to 2013 utilising a Tissue Microarray and our pilot study. Determining changes in molecular phenotype across time/distance can identify evolution and potential biomarker targets for early diagnosis and treatment or vaccine.
- Funding
- University of Tasmania Foundation Inc ($20,703)
- Scheme
- Grant-Dr Eric Guiler Tasmanian Devil Research Gran
- Administered By
- University of Tasmania
- Research Team
- Sohal SS
- Year
- 2016
- Description
- Aim: In an international first, this project aims to achieve the evaluation and identification of heparin molecules that inhibit the effect of several important inflammatory mediators involved in the pathogenesis of asthma, without possessing significant anticoagulant effect, with a view towards examining the efficacy of identified molecules in patients with asthma. Methodology: Heparin molecules will be separated and isolated using an ion-chromatography technique. Participants will attend the clinic where 50mL of blood will be taken by a qualified nurse. Mononuclear cells will be isolated from the collected blood. Then the cells will be activated to produce inflammatory mediators in the presence or absence of heparin fractions. Outcome: This research will evaluate and identify the novel molecules responsible for the anti-asthmatic activity of the parent heparin. This study would provide better insight into the mechanism(s) of heparin for its anti-asthmatic activity. It could open new avenues for the development of a heparin formulation with high anti-asthmatic properties but devoid of any anticoagulant activity. This could potentially resolve the safety and non-compliance issues objected upon in previous clinical trials.
- Funding
- Royal Hobart Hospital Research Foundation ($4,998)
- Scheme
- Grant-Starter
- Administered By
- University of Tasmania
- Research Team
- Hunter CJ; Patel RP; Stewart NJ; Sohal SS
- Year
- 2014
- Description
- Small airway fibrosis is the main contributor to physiological airway obstruction in chronic obstructive pulmonary disease (COPD). The other main airway pathology in COPD is lung cancer as up to 70% of smoking related lung cancer occurs in mild-moderate COPD. Epithelial mesenchymal transition (EMT) may underlie both pathological features and if true, will open up major new therapeutic possibilities. This project aims to investigate EMT in small and matching large airways of smokers/COPD.
- Funding
- Royal Hobart Hospital Research Foundation ($13,000)
- Scheme
- Grant-Clinical Research
- Administered By
- University of Tasmania
- Research Team
- Sohal SS; Walters EH; Hunter CJ; Hardikar AA
- Year
- 2014
- Description
- This project aims to develop a national registry of Idiopathic Pulmonary Fibrosis (IPF), obtain detailed clinical and personal information for risk factor assessment and blood for potential biomarkers.
- Funding
- National Health & Medical Research Council ($655,209)
- Scheme
- Grant-Project
- Administered By
- University of Sydney
- Research Team
- Corte T; Sohal SS; Walters EH; Hopkins P; Goh N; Glaspole I; Moodley Y; Reynolds P; Zappala C
- Period
- 2014 - 2016
- Grant Reference
- 1066128
- Description
- This project will continue work on airway inflammation and remodelling in smokers.
- Funding
- Lung Foundation Australia ($45,000)
- Scheme
- Scholarship-PhD
- Administered By
- University of Tasmania
- Research Team
- Walters EH; Sohal SS
- Period
- 2013 - 2015
Research Supervision
Current
2
Completed
12
Current
Degree | Title | Commenced |
---|---|---|
PhD | Pulmonary Arterial Remodelling and Role of Endothelial to Mesenchymal Transition (EndMT) in Smokers and in Patients with Small Airway Disease and COPD | 2018 |
PhD | The Trace Amine-associated Receptor 1 as a Target for the Development of New Anti-obesity Treatments | 2022 |
Completed
Degree | Title | Completed |
---|---|---|
Masters | SARS-CoV-2 (COVID-19) Adhesion Site Protein Upregulation in Small Airways, Type II Pneumocytes, and Alveolar Macrophages of Smokers and Patients with COPD Candidate: Samuel James Brake | 2024 |
PhD | Cellular and Airway Remodelling Changes in Asthma and COPD Overlap (ACO) Candidate: Surajit Dey | 2023 |
PhD | Pulmonary Arterial Remodelling and Role of Endothelial to Mesenchymal Transition (EndMT) in Patients with Idiopathic Pulmonary Fibrosis (IPF) Candidate: Archana Vijay Gaikwad | 2023 |
PhD | The Role of Zinc and the Zip7 Transporter in Disease Processes Associated with IR in Skeletal Muscle Candidate: Shaghayegh Norouzi | 2019 |
PhD | Role of NLRP3 in Colitis and Colitis Associated Colorectal Cancer Candidate: Agampodi Promoda Prasadini Perera | 2019 |
PhD | Further Immunohistochemical (IHC) Characterisation of Devil Facial Tumour Disease 1 (DFT1) in the Tasmanian Devil (Sarcophilus harrisii) Candidate: Dane Adam Hayes | 2019 |
PhD | Understanding Cellular Changes and Mediators of Airway Remodelling in COPD Candidate: Mathew Suji Eapen | 2018 |
PhD | Studies on Epithelial Mesenchymal Transition (EMT) in 'Smoking-Related' Airway Disease Candidate: Malik Quasir Mahmood | 2016 |
PhD | Studies on Microbial Adhesion Factors in Smoking and Chronic Obstructive Pulmonary Disease (COPD) Candidate: Shakti Dhar Shukla | 2016 |
PhD | Heparins and Fucoidans: Future therapeutic options for ulcerative colitis Candidate: Qi Ying Lean | 2016 |
PhD | Non-anticoagulant Derivatives of Heparin for the Management of Asthma: Distant dream or close reality? Candidate: Madhur Shastri | 2015 |
Masters | Drivers of Epithelial-Mesenchymal Transition in Chronic Obstructive Pulmonary Disease Candidate: Kaosia Nowrin | 2015 |