Profiles

David Small

Prof David Small

David Small

Professorial Research Fellow
Menzies Institute for Medical Research

Hobart CBD Campuses

(03) 6226 7348 (phone)

D.H.Small@utas.edu.au

Prof Small is an NHMRC Senior Research Fellow at the Menzies Institute for Medical Research, University of Tasmania. David's research interests include neurodegenerative diseases (development of diagnostic tests for Alzheimer's disease, mechanisms of amyloid folding and aggregation, amyloid toxicity, therapeutics), cholinergic neurobiology (acetylcholinesterase), protein glycosylation, extracellular matrix and heparan sulfate proteoglycans, protease and neuronal cell biology. His work encompasses papers in the fields of nanotechnology (scanning tunnelling microscopy), biochemistry, molecular and cell biology, neuropharmacology, clinical diagnostics, computational neuroscience and behavioural testing. He is well known internationally in the field of Alzheimer' disease, especially for his work on the molecular mechanisms that underlie changes in acetylcholinesterase expression in Alzheimer's disease brain and on the structure and metabolism of the b-amyloid precursor protein.

Biography

Professor Small was born in 1956 in Hobart, Tasmania, but he grew up and received most of his early education in Canada. He returned to Australia in late 1977 and completed his PhD in the biochemistry department of The University of Melbourne in 1981. After postdoctoral research at MIT (Boston), he returned to Australia (Flinders Uni, Adelaide) in 1985. He moved back to the University of Melbourne in 1986 as an NHMRC Australian Postdoctoral Fellow. In 1991, he was awarded an NHMRC RD Wright Fellowship and in 1993 he was awarded an NHMRC Research Fellowship. He became an NHMRC Senior Research Fellow in 1996 and has been continuously within the NHMRC fellowships scheme ever since. He moved to Monash University in March 2003, and in 2008, he took up his present position at the Menzies Institute for Medical Research at the University of Tasmania. He has received continuous NHMRC project/program grant funding since 1990.

Career summary

Qualifications

PhD, University of Melbourne. 1981. Thesis: Methylation of Myelin Basic Protein
BSc. (High Hons), University of Saskatchewan, Canada. 1977

Languages (other than English)

French (fluent/bilingual proficiency)
Spanish (excellent working proficiency)
German (basic proficiency)

Memberships

Professional practice

Australian Neuroscience Society (ANS), Editor (an Executive position) (2008-2012)
Asian Pacific Society for Neurochemistry Council and membership of the International Proteolysis Society Scientific Advisory Committee, Member (2009)
International Society for Neurochemistry Publications Committee, Member (2006-2008)
International Society for Neurochemistry Internet Committee, Member (2001-2004)
International Scientific Advisory Committee for Cholinesterase Conferences, Member (1998-2004)
International Conference on Peptidases and Neuropeptide Processing, Chair (1991)

Administrative expertise

Deputy Director, Monash University Centre for Brain and Behaviour (2003-2006)
Deputy Director, Menzies Research Institute Tasmania (2009-2011)
NHMRC Grant Review Panels
NHMRC Fellowships Panel

Teaching

Neuroscience, Alzheimer's Disease, Biochemistry, Molecular Biology, Cell Biology

Research Invitations

Prof Small has received more than 50 invitations to chair and speak at major international conferences.

View more on Professor David Small in WARP

Research Themes

Professor Small's research interests centre on the molecular neurobiology of Alzheimer's disease and align with the University's theme of Better Health. His team is looking at basic mechanisms of disease causation with a view to the development of novel therapeutic strategies.

Collaboration

Within the University of Tasmania Prof Small works in collaboration with Dr Lisa Foa and Dr Kaylene Young (Menzies Institute for Medical Research). He also collaborates with Profs Mibel Aguilar and Helena Parkington (Monash University).

Current projects

Fields of Research

Neurosciences (320999)
Cellular nervous system (320902)
Cell neurochemistry (310104)
Neurology and neuromuscular diseases (320905)
Central nervous system (320903)
Biochemistry and cell biology (310199)
Pharmaceutical sciences (321405)
Autonomic nervous system (320901)
Clinical chemistry (incl. diagnostics) (320202)
Medical biochemistry - proteins and peptides (incl. medical proteomics) (320506)
Peripheral nervous system (320906)
Basic pharmacology (321401)
Clinical pharmacology and therapeutics (321402)
Biologically active molecules (340401)
Cell physiology (320801)
Plant cell and molecular biology (310803)
Animal cell and molecular biology (310902)
Animal physiology - systems (310910)
Cell development, proliferation and death (310102)

Research Objectives

Clinical health (200199)
Expanding knowledge in the health sciences (280112)
Expanding knowledge in the biological sciences (280102)
Health related to ageing (200502)
Other health (209999)
Human pharmaceutical treatments (240803)
Human biological preventatives (240801)
Coastal or estuarine biodiversity (180203)
Preventive medicine (200412)
Mental health (200409)
Aquaculture fin fish (excl. tuna) (100202)
Expanding knowledge in the environmental sciences (280111)
Evaluation of health and support services (200299)

Publications

Prof Small's published work has an h-index of 40 and has been cited more than 4970 times. He has published 170 papers in refereed international journals, including major journals such as Proc. Natl. Acad. Sci. USA (1), Trends Biochem. Sci. (1), Nature Rev. Neurosci. (1), Trends Neurosci. (2), Neuron (1), Lancet (1), J. Neurosci. (3), Trends Mol. Med. (1), J. Biol. Chem. (6), Biochemistry (6), Brain (1) and J. Neurochem.(30).

Prof Small has been twice Deputy Chief Editor (DCE) of J Neurochem and has been a senior editor (equivalent to DCE) of Journal of Neuroscience Research and Journal of Alzheimer's Disease. He has served on the editorial board of 7 journals.

Total publications

129

Highlighted publications

(12 outputs)

Year	Type	Citation
2008	Journal Article	Petratos S, Li QX, George AJ, Hou X, Kerr ML, et al., 'The beta-amyloid protein of Alzheimers disease increases neuronal CRMP-2 phosphorylation by a Rho-GTP mechanism', Brain, 131, (1) pp. 90-108. ISSN 0006-8950 (2008) [Refereed Article] DOI: 10.1093/brain/awm260 [eCite] [Details] Citations: Scopus - 159Web of Science - 149 Tweet
2008	Review	Small DH, 'Network dysfunction in Alzheimer's disease: does synaptic scaling drive disease progression?', Trends in Molecular Medicine, 14, (3) pp. 103-108. (2008) [Substantial Review] DOI: 10.1016/j.molmed.2007.12.006 [eCite] [Details] Citations: Scopus - 76Web of Science - 66 Tweet
2007	Journal Article	Small DH, Maksel D, Kerr ML, Ng J, Hou X, et al., 'The β-amyloid protein of Alzheimer's disease binds to membrane lipids but does not bind to the α7 nicotinic acetylcholine receptor', Journal of Neurochemistry, 101, (6) pp. 1527-1538. ISSN 0022-3042 (2007) [Refereed Article] DOI: 10.1111/j.1471-4159.2006.04444.x [eCite] [Details] Citations: Scopus - 87Web of Science - 86 Tweet
2006	Journal Article	Losic D, Martin LL, Mechler A, Aguilar MI, Small DH, 'High resolution scanning tunnelling microscopy of the β-amyloid protein (Aβ1-40) of Alzheimer's disease suggests a novel mechanism of oligomer assembly', Journal of Structural Biology, 155, (1) pp. 104-110. ISSN 1047-8477 (2006) [Refereed Article] DOI: 10.1016/j.jsb.2006.02.013 [eCite] [Details] Citations: Scopus - 56Web of Science - 53 Tweet
2004	Journal Article	Small DH, 'Do acetylcholinesterase inhibitors boost synaptic scaling in Alzheimer's disease?', Trends in Neurosciences, 27, (5) pp. 245-249. ISSN 0166-2236 (2004) [Refereed Article] DOI: 10.1016/j.tins.2004.03.006 [eCite] [Details] Citations: Scopus - 35Web of Science - 28 Tweet
2001	Journal Article	Small DH, Mok SS, Bornstein JC, 'Alzheimer's disease and Aβ toxicity: from top to bottom', Nature Reviews Neuroscience, 2 pp. 595-598. ISSN 1471-003X (2001) [Refereed Article] [eCite] [Details]
1997	Journal Article	Saez-Valero J, Sberna G, McLean CA, Masters CL, Small DH, 'Glycosylation of acetylcholinesterase as diagnostic marker for Alzheimer's disease', The Lancet, 350 pp. 929. ISSN 0140-6736 (1997) [Letter or Note in Journal] [eCite] [Details]
1996	Journal Article	Williamson TG, Mok SS, Henry A, Cappai R, Lander AD, et al., 'Secreted Glypican Binds to the Amyloid Precursor Protein of Alzheimer's Disease (APP) and Inhibits APP-induced Neurite Outgrowth', Journal of Biological Chemistry, 271, (49) pp. 31215-31221. ISSN 0021-9258 (1996) [Refereed Article] DOI: 10.1074/jbc.271.49.31215 [eCite] [Details] Citations: Scopus - 88Web of Science - 89 Tweet
1995	Journal Article	Small DH, Reed G, Whitefield B, Nurcombe V, 'Cholinergic Regulation of Neurite Outgrowth from Isolated Chick Sympathetic Neurons in Culture', Journal of Neuroscience, 15, (1) pp. 144-151. ISSN 0270-6474 (1995) [Refereed Article] [eCite] [Details] Citations: Web of Science - 131
1994	Journal Article	Small DH, Nurcombe V, Reed G, Clarris H, Moir R, et al., 'A Heparin-binding Domain in the Amyloid Protein Precursor of Alzheimer's Disease Is Involved in the Regulation of Neurite Outgrowth', Journal of Neuroscience, 14, (4) pp. 2117-2127. ISSN 0270-6474 (1994) [Refereed Article] [eCite] [Details] Citations: Web of Science - 325
1992	Journal Article	Milward EA, Papadopoulos R, Fuller SJ, Moir RD, Small D, et al., 'The Amyloid Protein Precursor of Alzheimer's Disease Is a Mediator of the Effects of Nerve Growth Factor on Neurite Outgrowth', Neuron, 9 pp. 129-137. ISSN 0896-6273 (1992) [Refereed Article] [eCite] [Details]
1992	Journal Article	Small DH, Nurcombe V, Moir R, Michaelson S, Monard D, et al., 'Association and Release of the Amyloid Protein Precursor of Alzheimer's Disease from Chick Brain Extracellular Matrix', Journal of Neuroscience, 12, (11) pp. 4143-4150. ISSN 0270-6474 (1992) [Refereed Article] [eCite] [Details] Citations: Web of Science - 84

Journal Article

(106 outputs)

Year	Citation	Altmetrics
2020	Juliano JP, Small DH, Aguilar M-I, 'Peptidomimetic modulators of BACE1', Australian Journal of Chemistry, 73, (4) pp. 366-376. ISSN 0004-9425 (2020) [Refereed Article] DOI: 10.1071/CH19594 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Tweet
2020	Shepherd CE, Affleck AJ, Bahar AY, Carew-Jones F, Gregory G, et al., 'Alzheimer's amyloid-β and tau protein accumulation is associated with decreased expression of the LDL receptor-associated protein in human brain tissue', Brain and Behavior Article e01672. ISSN 2162-3279 (2020) [Refereed Article] DOI: 10.1002/brb3.1672 [eCite] [Details] Citations: Scopus - 4Web of Science - 3 Tweet
2018	Southam KA, Stennard F, Pavez C, Small DH, 'Knockout of amyloid β protein precursor (APP) expression alters synaptogenesis, neurite branching and axonal morphology of hippocampal neurons', Neurochemical Research pp. 1-10. ISSN 0364-3190 (2018) [Refereed Article] DOI: 10.1007/s11064-018-2512-0 [eCite] [Details] Citations: Scopus - 21Web of Science - 22 Co-authors: Southam KA; Stennard F; Pavez C Tweet
2017	Cui H, King AE, Jacobson GA, Small DH, 'Peripheral treatment with enoxaparin exacerbates amyloid plaque pathology in Tg2576 mice', Journal of Neuroscience Research, 95, (4) pp. 992-999. ISSN 0360-4012 (2017) [Refereed Article] DOI: 10.1002/jnr.23880 [eCite] [Details] Citations: Scopus - 5Web of Science - 3 Co-authors: Cui H; King AE; Jacobson GA Tweet
2016	Smith AI, Rajapakse NW, Kleifeld O, Lomonte B, Sikanyika NL, et al., 'N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin', Scientific Reports, 6 Article 22413. ISSN 2045-2322 (2016) [Refereed Article] DOI: 10.1038/srep22413 [eCite] [Details] Citations: Scopus - 11Web of Science - 10 Tweet
2016	Southam KA, Vincent AJ, Small DH, 'Do microglia default on network maintenance in Alzheimer's disease?', Journal of Alzheimer's Disease, 51, (3) pp. 657-669. ISSN 1387-2877 (2016) [Refereed Article] DOI: 10.3233/JAD-151075 [eCite] [Details] Citations: Scopus - 15Web of Science - 14 Co-authors: Southam KA; Vincent AJ Tweet
2014	Bolos M, Hu Y, Young KM, Foa L, Small DH, 'Neurogenin 2 mediates amyloid-β precursor protein-stimulated neurogenesis', Journal of Biological Chemistry, 289, (45) pp. 31253-31261. ISSN 0021-9258 (2014) [Refereed Article] DOI: 10.1074/jbc.M114.581918 [eCite] [Details] Citations: Scopus - 14Web of Science - 14 Co-authors: Bolos M; Hu Y; Young KM; Foa L Tweet
2014	Dawkins E, Gasperini R, Hu Y, Cui H, Vincent AJ, et al., 'The N-terminal fragment of the β-amyloid precursor protein of Alzheimer's disease (N-APP) binds to phosphoinositide-rich domains on the surface of hippocampal neurons', Journal of Neuroscience Research, 92, (11) pp. 1478-1489. ISSN 1097-4547 (2014) [Refereed Article] DOI: 10.1002/jnr.23422 [eCite] [Details] Citations: Scopus - 5Web of Science - 5 Co-authors: Dawkins E; Gasperini R; Hu Y; Cui H; Vincent AJ; Bolos M; Young KM; Foa L Tweet
2014	Dawkins E, Small DH, 'Insights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's disease', Journal of Neurochemistry, 129, (5) pp. 756-769. ISSN 0022-3042 (2014) [Refereed Article] DOI: 10.1111/jnc.12675 [eCite] [Details] Citations: Scopus - 172Web of Science - 165 Co-authors: Dawkins E Tweet
2014	Small DH, Hu Y, Bolos M, Dawkins E, Foa L, et al., 'β-Amyloid precursor protein: function in stem cell development and Alzheimer's disease brain', Neurodegenerative Diseases, 13, (2-3) pp. 96-98. ISSN 1660-2854 (2014) [Refereed Article] DOI: 10.1159/000353686 [eCite] [Details] Citations: Scopus - 6Web of Science - 6 Co-authors: Hu Y; Bolos M; Dawkins E; Foa L; Young KM Tweet
2013	Cui H, Freeman C, Jacobson GA, Small DH, 'Proteoglycans in the central nervous system: Role in development, neural repair, and Alzheimer's disease', IUBMB Life, 65, (2) pp. 108-120. ISSN 1521-6543 (2013) [Refereed Article] DOI: 10.1002/iub.1118 [eCite] [Details] Citations: Scopus - 64Web of Science - 62 Co-authors: Cui H; Jacobson GA Tweet
2013	Hu Y, Hung AC, Cui H, Dawkins E, Bolos M, et al., 'Role of cystatin C in amyloid precursor protein-induced proliferation of neural stem/progenitor cells', Journal of Biological Chemistry, 288, (26) pp. 18853-18862. ISSN 0021-9258 (2013) [Refereed Article] DOI: 10.1074/jbc.M112.443671 [eCite] [Details] Citations: Scopus - 25Web of Science - 27 Co-authors: Hu Y; Hung AC; Cui H; Dawkins E; Bolos M; Foa L; Young KM Tweet
2012	Cui H, Hung AC, Freeman C, Narkowicz C, Jacobson GA, et al., 'Size and sulfation are critical for the effect of heparin on APP processing and A beta production', Journal of Neurochemistry, 123, (3) pp. 447-457. ISSN 0022-3042 (2012) [Refereed Article] DOI: 10.1111/j.1471-4159.2012.07929.x [eCite] [Details] Citations: Scopus - 12Web of Science - 11 Co-authors: Cui H; Hung AC; Narkowicz C; Jacobson GA Tweet
2012	Gasperini RJ, Small DH, 'Neurodegeneration in Familal Amyloidotic Polyneuropathy', Clinical and Experimental Pharmacology and Physiology, 39, (8) pp. 680-683. ISSN 0305-1870 (2012) [Refereed Article] DOI: 10.1111/j.1440-1681.2011.05607.x [eCite] [Details] Citations: Scopus - 7Web of Science - 5 Co-authors: Gasperini RJ Tweet
2012	Mitchell CB, Gasperini RJ, Small DH, Foa LC, 'STIM1 is necessary for store-operated calcium entry in turning growth cones', Journal of Neurochemistry, 122, (6) pp. 1155-66. ISSN 0022-3042 (2012) [Refereed Article] DOI: 10.1111/j.1471-4159.2012.07840.x [eCite] [Details] Citations: Scopus - 39Web of Science - 38 Co-authors: Gasperini RJ; Foa LC Tweet
2012	Silveyra M-X, Garcia-Ayllon M-S, de Barreda EG, Small DH, Martinez S, et al., 'Altered expression of brain acetylcholinesterase in FTDP-17 human tau transgenic mice', Neurobiology of Aging: Experimental and Clinical Research, 33, (3) pp. 624.e23- 624.e34. ISSN 0197-4580 (2012) [Refereed Article] DOI: 10.1016/j.neurobiolaging.2011.03.006 [eCite] [Details] Citations: Scopus - 22Web of Science - 11 Tweet
2012	Small DH, 'Dysregulation of Ca²⁺ homeostasis in Alzheimer's disease: role in acetylcholinesterase production and AMPA receptor internalization', Neurodegenerative Diseases, 10, (1-4) pp. 76-79. ISSN 1660-2854 (2012) [Refereed Article] DOI: 10.1159/000333126 [eCite] [Details] Citations: Scopus - 5Web of Science - 6 Tweet
2012	Small DH, Aguilar M-I, 'Targeting pre-mRNA splicing: a BACE-ic strategy for AD drug development?', Journal of Neurochemistry, 121, (5) pp. 695-696. ISSN 0022-3042 (2012) [Letter or Note in Journal] DOI: 10.1111/j.1471-4159.2012.07679.x [eCite] [Details] Tweet
2012	Zhai J, Lee TH, Small DH, Aguilar M-I, 'Characterization of early stage intermediates in the nucleation phase of Aβ aggregation', Biochemistry, 51, (6) pp. 1070-1078. ISSN 0006-2960 (2012) [Refereed Article] DOI: 10.1021/bi201871r [eCite] [Details] Citations: Scopus - 25Web of Science - 23 Tweet
2011	Cui H, Hung AC, Klaver DW, Suzuki T, Freeman C, et al., 'Effects of heparin and enoxaparin on APP processing and Aβ production in primary cortical neurons from Tg2576 mice', PLoS One, 6, (7) Article e23007. ISSN 1932-6203 (2011) [Refereed Article] DOI: 10.1371/journal.pone.0023007 [eCite] [Details] Citations: Scopus - 25Web of Science - 15 Co-authors: Cui H; Hung AC; Klaver DW; Narkowicz C; Jacobson GA Tweet
2011	Garcia-Ayllon MS, Small DH, Avila J, Saez-Valero J, 'Revisiting the role of acetylcholinesterase in Alzheimer's disease: cross-talk with P-tau and β-amyloid', Frontiers in Molecular Neuroscience, 4 Article 22. ISSN 1662-5099 (2011) [Refereed Article] DOI: 10.3389/fnmol.2011.00022 [eCite] [Details] Citations: Scopus - 172 Tweet
2011	Gasperini RJ, Hou X, Parkington H, Coleman H, Klaver DW, et al., 'TRPM8 and Na_v 1.8 sodium channels are required for transthyretin-induced calcium influx in growth cones of small-diameter TrkA-positive sensory neurons', Molecular Neurodegeneration, 6, (19) pp. 1-12. ISSN 1750-1326 (2011) [Refereed Article] DOI: 10.1186/1750-1326-6-19 [eCite] [Details] Citations: Scopus - 22Web of Science - 17 Co-authors: Gasperini RJ; Klaver DW; Vincent AJ; Foa LC Tweet
2011	Hou X, Small DH, Aguilar MI, 'Surface Plasmon Resonance Spectroscopy: A New Lead in Studying the Membrane Binding of Amyloidogenic Transthyretin', Methods in Molecular Biology, 752 pp. 215-228. ISSN 1064-3745 (2011) [Refereed Article] DOI: 10.1007/978-1-60327-223-0_14 [eCite] [Details] Citations: Scopus - 1 Tweet
2010	Kerr ML, Gasperini R, Gibbs ME, Hou X, Shepherd CE, et al., 'Inhibition of Aβ aggregation and neurotoxicity by the 39-kDa receptor-associated protein', Journal of Neurochemistry, 112, (5) pp. 1199-1209. ISSN 0022-3042 (2010) [Refereed Article] DOI: 10.1111/j.1471-4159.2009.06540.x [eCite] [Details] Citations: Scopus - 8Web of Science - 8 Co-authors: Gasperini R; Foa L Tweet
2010	Klaver D, Hung AC, Gasperini R, Foa L, Aguilar MI, et al., 'Effect of Heparin on APP Metabolism and Aβ Production in Cortical Neurons', Neurodegenerative Diseases, 7, (1-3) pp. 187-189. ISSN 1660-2854 (2010) [Refereed Article] DOI: 10.1159/000295661 [eCite] [Details] Citations: Scopus - 9Web of Science - 9 Co-authors: Klaver D; Hung AC; Gasperini R; Foa L Tweet
2010	Klaver DW, Wilce MCJ, Cui H, Hung AC, Gasperini R, et al., 'Is BACE1 a suitable therapeutic target for the treatment of Alzheimer's disease? Current strategies and future directions', Biological Chemistry: Official Journal of The German Society for Biochemistry and Molecular Biology, 391, (8) pp. 849-859. ISSN 1431-6730 (2010) [Refereed Article] DOI: 10.1515/BC.2010.089 [eCite] [Details] Citations: Scopus - 39Web of Science - 34 Co-authors: Klaver DW; Cui H; Hung AC; Gasperini R; Foa L Tweet
2010	Klaver DW, Wilce MCJ, Gasperini R, Freeman C, Juliano JP, et al., 'Glycosaminoglycan-induced activation of the β-secretase (BACE1) of Alzheimer's disease', Journal of Neurochemistry, 112, (6) pp. 1552-1561. ISSN 0022-3042 (2010) [Refereed Article] DOI: 10.1111/j.1471-4159.2010.06571.x [eCite] [Details] Citations: Scopus - 21Web of Science - 20 Co-authors: Klaver DW; Gasperini R; Foa L Tweet
2010	Liu SJ, Gasperini R, Foa L, Small DH, 'Amyloid-beta Decreases Cell-Surface AMPA Receptors by Increasing Intracellular Calcium and Phosphorylation of GluR2', Journal of Alzheimer's Disease, 21, (2) pp. 655-666. ISSN 1387-2877 (2010) [Refereed Article] DOI: 10.3233/JAD-2010-091654 [eCite] [Details] Citations: Scopus - 60Web of Science - 58 Co-authors: Liu SJ; Gasperini R; Foa L Tweet
2010	Small DH, Klaver DW, Foa L, 'Presenilins and the gamma-secretase: still a complex problem', Molecular Brain, 3, (1) pp. 1-6. ISSN 1756-6606 (2010) [Refereed Article] DOI: 10.1186/1756-6606-3-7 [eCite] [Details] Citations: Scopus - 23Web of Science - 23 Co-authors: Klaver DW; Foa L Tweet
2010	Vincent AJ, Gasperini R, Foa L, Small DH, 'Astrocytes in Alzheimer's Disease: Emerging Roles in Calcium Dysregulation and Synaptic Plasticity', Journal of Alzheimer's Disease, 22, (3) pp. 699-714. ISSN 1387-2877 (2010) [Refereed Article] DOI: 10.3233/JAD-2010-101089 [eCite] [Details] Citations: Scopus - 65Web of Science - 63 Co-authors: Vincent AJ; Gasperini R; Foa L Tweet
2009	Beckman M, Freeman C, Parish CR, Small DH, 'Activation of cathepsin D by glycosaminoglycans', The F E B S Journal, 276, (24) pp. 7343-7352. ISSN 1742-464X (2009) [Refereed Article] DOI: 10.1111/j.1742-4658.2009.07444.x [eCite] [Details] Citations: Scopus - 18Web of Science - 18 Tweet
2009	Small DH, 'Dysregulation of Calcium Homeostasis in Alzheimer's Disease', Neurochemical Research, 34, (10) pp. 1824-1829. ISSN 0364-3190 (2009) [Refereed Article] DOI: 10.1007/s11064-009-9960-5 [eCite] [Details] Citations: Scopus - 85Web of Science - 82 Tweet
2009	Small DH, Gasperini R, Vincent AJ, Hung AC, Foa L, 'The Role of Aβ-Induced Calcium Dysregulation in the Pathogenesis of Alzheimer's Disease', Journal of Alzheimer's Disease, 16, (2) pp. 225-233. ISSN 1387-2877 (2009) [Refereed Article] DOI: 10.3233/JAD-2009-0951 [eCite] [Details] Citations: Scopus - 67Web of Science - 62 Co-authors: Gasperini R; Vincent AJ; Hung AC; Foa L Tweet
2008	Azari MF, Ozturk E, Profyris C, Wang S, Small DH, et al., 'LIF treatment reduces Nogo-A deposits in spinal cord injury modulating Rho GTPase activity and CRMP-2 phosphorylation', Journal of Neurodegeneration and Regeneration, 1, (1) pp. 23-29. ISSN 1932-1481 (2008) [Refereed Article] [eCite] [Details]
2008	Gibbs ME, Maksel D, Gibbs Z, Hou X, Summers RJ, et al., 'Memory loss caused by s-amyloid protein is rescued by as3-adrenoceptor agonist', Neurobiology of Aging, 31, (4) EJ ISSN 0197-4580 (2008) [Refereed Article] DOI: 10.1016/j.neurobiolaging.2008.05.018 [eCite] [Details] Citations: Scopus - 40Web of Science - 40 Tweet
2008	Hou X, Mechler A, Martin LL, Aguilar MI, Small DH, 'Cholesterol and anionic phospholipids increase the binding of amyloidogenic transthyretin to lipid membranes', Biochimica et Biophysica Acta, 1778, (1) pp. 198-205. ISSN 0005-2736 (2008) [Refereed Article] DOI: 10.1016/j.bbamem.2007.09.018 [eCite] [Details] Citations: Scopus - 26Web of Science - 25 Tweet
2008	Petratos S, Li QX, George AJ, Hou X, Kerr ML, et al., 'The beta-amyloid protein of Alzheimers disease increases neuronal CRMP-2 phosphorylation by a Rho-GTP mechanism', Brain, 131, (1) pp. 90-108. ISSN 0006-8950 (2008) [Refereed Article] DOI: 10.1093/brain/awm260 [eCite] [Details] Citations: Scopus - 159Web of Science - 149 Tweet
2007	Hou X, Aguilar MI, Small DH, 'Transthyretin and familial amyloidotic polyneuropathy: Recent progress in understanding the molecular mechanism of neurodegeneration', The F E B S Journal, 274, (7) pp. 1637-1650. ISSN 1742-464X (2007) [Refereed Article] DOI: 10.1111/j.1742-4658.2007.05712.x [eCite] [Details] Citations: Scopus - 145Web of Science - 128 Tweet
2007	Hou X, Parkington HC, Coleman HA, Mechler A, Martin LL, et al., 'Transthyretin oligomers induce calcium influx via voltage-gated calcium channels', Journal of Neurochemistry, 100, (2) pp. 446-457. ISSN 0022-3042 (2007) [Refereed Article] DOI: 10.1111/j.1471-4159.2006.04210.x [eCite] [Details] Citations: Scopus - 62Web of Science - 52 Tweet
2007	Small DH, 'Neural Network Dysfunction in Alzheimer's Disease: A Drug Development Perspective', Drug News and Perspectives: The International Drug Newsmagazine, 20, (9) pp. 557-563. ISSN 0214-0934 (2007) [Refereed Article] DOI: 10.1358/dnp.2007.20.9.1162245 [eCite] [Details] Citations: Scopus - 8Web of Science - 8 Tweet
2007	Small DH, Maksel D, Kerr ML, Ng J, Hou X, et al., 'The β-amyloid protein of Alzheimer's disease binds to membrane lipids but does not bind to the α7 nicotinic acetylcholine receptor', Journal of Neurochemistry, 101, (6) pp. 1527-1538. ISSN 0022-3042 (2007) [Refereed Article] DOI: 10.1111/j.1471-4159.2006.04444.x [eCite] [Details] Citations: Scopus - 87Web of Science - 86 Tweet
2006	Azari MF, Profyris C, Small DH, Karnezis T, Bernard CC, 'Leukemia Inhibitory Factor Arrests Oligodendrocyte Death and Demyelination in Spinal Cord Injury', Journal of Neuropathology and Experimental Neurology, 65, (9) pp. 914-929. ISSN 0022-3069 (2006) [Refereed Article] DOI: 10.1097/01.jnen.0000235855.77716.25 [eCite] [Details] Citations: Scopus - 55Web of Science - 53 Tweet
2006	Beckman M, Holsinger RMD, Small DH, 'Heparin Activates β-Secretase (BACE1) of Alzheimer's Disease and Increases Autocatalysis of the Enzyme', Biochemistry, 45, (21) pp. 6703-6714. ISSN 0006-2960 (2006) [Refereed Article] DOI: 10.1021/bi052498t [eCite] [Details] Citations: Scopus - 47Web of Science - 46 Tweet
2006	Losic D, Martin LL, Aguilar MI, Small DH, 'β-amyloid fibril formation is promoted by step edges of highly oriented pyrolytic graphite', Biopolymers: Original Research on Biological Molecules and Assemblies, 84, (5) pp. 519-526. ISSN 0006-3525 (2006) [Refereed Article] DOI: 10.1002/bip.20549 [eCite] [Details] Citations: Scopus - 40Web of Science - 43 Tweet
2006	Losic D, Martin LL, Mechler A, Aguilar MI, Small DH, 'High resolution scanning tunnelling microscopy of the β-amyloid protein (Aβ1-40) of Alzheimer's disease suggests a novel mechanism of oligomer assembly', Journal of Structural Biology, 155, (1) pp. 104-110. ISSN 1047-8477 (2006) [Refereed Article] DOI: 10.1016/j.jsb.2006.02.013 [eCite] [Details] Citations: Scopus - 56Web of Science - 53 Tweet
2006	Mok SS, Losic D, Barrow CJ, Turner BJ, Masters CL, et al., 'The β-amyloid peptide of Alzheimer's disease decreases adhesion of vascular smooth muscle cells to the basement membrane', Journal of Neurochemistry, 96, (1) pp. 53-64. ISSN 0022-3042 (2006) [Refereed Article] DOI: 10.1111/j.1471-4159.2005.03539.x [eCite] [Details] Citations: Scopus - 29Web of Science - 29 Tweet
2006	Small DH, Cappai R, 'Alois Alzheimer and Alzheimer's disease: a centennial perspective', Journal of Neurochemistry, 99, (3) pp. 708-710. ISSN 0022-3042 (2006) [Refereed Article] DOI: 10.1111/j.1471-4159.2006.04212.x [eCite] [Details] Citations: Scopus - 63Web of Science - 57 Tweet
2005	Aguilar MI, Small DH, 'Surface Plasmon Resonance for the Analysis of β-Amyloid Interactions and Fibril Formation in Alzheimer's Disease Research', Neurotoxicity Research: An International Journal on Processes and Mechanisms in Neurodegeneration, Apoptosis, Neuroprotection and Regeneration, 7, (1-2) pp. 17-27. ISSN 1029-8428 (2005) [Refereed Article] DOI: 10.1007/BF03033773 [eCite] [Details] Citations: Scopus - 47Web of Science - 45 Tweet
2005	Hou X, Richardson SJ, Aguilar MI, Small DH, 'Binding of Amyloidogenic Transthyretin to the Plasma Membrane Alters Membrane Fluidity and Induces Neurotoxicity', Biochemistry, 44, (30) pp. 11618-11627. ISSN 0006-2960 (2005) [Refereed Article] DOI: 10.1021/bi050700m [eCite] [Details] Citations: Scopus - 63Web of Science - 56 Tweet
2005	Kerr ML, Small DH, 'Cytoplasmic Domain of the â-Amyloid Protein Precursor of Alzheimer's Disease: Function, Regulation of Proteolysis, and Implications for Drug Development', Journal of Neuroscience Research, 80, (2) pp. 151-159. ISSN 0360-4012 (2005) [Refereed Article] DOI: 10.1002/jnr.20408 [eCite] [Details] Citations: Scopus - 38Web of Science - 32 Tweet
2005	Small DH, 'Acetylcholinesterase inhibitors for the treatment of dementia in Alzheimer's disease: do we need new inhibitors?', Expert Opinion on Emerging Drugs, 10, (4) pp. 817-825. ISSN 1744-7623 (2005) [Refereed Article] DOI: 10.1517/14728214.10.4.817 [eCite] [Details] Citations: Scopus - 38 Tweet
2005	Small DH, 'Biochemical, Cellular and Behavioural Aspects of Neurodegeneration: the View from Down Under', Neurotoxicity Research: An International Journal on Processes and Mechanisms in Neurodegeneration, Apoptosis, Neuroprotection and Regeneration, 7, (1-2) pp. 1-3. ISSN 1029-8428 (2005) [Contribution to Refereed Journal] DOI: 10.1007/BF03033771 [eCite] [Details] Citations: Scopus - 1Web of Science - 2 Tweet
2004	Fodero LR, Mok SS, Losic D, Martin LL, Aguilar MI, et al., 'α7-nicotinic acetylcholine receptors mediate an Aβ1-42-induced increase in the level of acetylcholinesterase in primary cortical neurons', Journal of Neurochemistry, 88, (5) pp. 1186-1193. ISSN 0022-3042 (2004) [Refereed Article] DOI: 10.1046/j.1471-4159.2003.02296.x [eCite] [Details] Citations: Scopus - 74Web of Science - 70 Tweet
2004	Small DH, 'Mechanisms of synaptic homeostasis in Alzheimer's disease', Current Alzheimer Research, 1, (1) pp. 27-32. ISSN 1567-2050 (2004) [Refereed Article] DOI: 10.2174/1567205043480573 [eCite] [Details] Citations: Scopus - 31Web of Science - 27 Tweet
2004	Small DH, 'Do acetylcholinesterase inhibitors boost synaptic scaling in Alzheimer's disease?', Trends in Neurosciences, 27, (5) pp. 245-249. ISSN 0166-2236 (2004) [Refereed Article] DOI: 10.1016/j.tins.2004.03.006 [eCite] [Details] Citations: Scopus - 35Web of Science - 28 Tweet
2004	Small DH, Losic D, Martin LL, Turner BJ, Freidhuber A, et al., 'Alzheimer's disease therapeutics: new approaches to an ageing problem', I U B M B Life: (International Union of Biochemistry and Molecular Biology), 56, (4) pp. 203-208. ISSN 1521-6543 (2004) [Refereed Article] DOI: 10.1080/15216540410001709211 [eCite] [Details] Citations: Scopus - 8Web of Science - 5 Tweet
2003	Klug GM, Losic D, Subasinghe SS, Aguilar MI, Martin LL, et al., 'β Amyloid protein oligomers induced by metal ions and acid pH are distinct from those generated by slow spontaneous ageing at neutral pH', The FEBS Journal, 270, (21) pp. 4282-4293. ISSN 1742-464X (2003) [Refereed Article] DOI: 10.1046/j.1432-1033.2003.03815.x [eCite] [Details] Citations: Scopus - 101Web of Science - 96 Tweet
2003	Nunan J, Williamson NA, Hill AF, Sernee MF, Masters CL, et al., 'Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease β-amyloid protein precursor: effect of C-terminal truncation on the production of β-amyloid protein', Journal of Neuroscience Research, 74, (3) pp. 378-385. ISSN 0360-4012 (2003) [Refereed Article] DOI: 10.1002/jnr.10646 [eCite] [Details] Citations: Scopus - 52Web of Science - 56 Tweet
2003	Saez-Valero J, Fodero LR, Sjogren M, Andreasen N, Amici S, et al., 'Glycosylation of acetylcholinesterase and butyrylcholinesterase changes as a function of the duration of Alzheimer's disease', Journal of Neuroscience Research, 72, (4) pp. 520-526. ISSN 0360-4012 (2003) [Refereed Article] DOI: 10.1002/jnr.10599 [eCite] [Details] Citations: Scopus - 50Web of Science - 48 Tweet
2003	Saez-Valero J, Fodero LR, White AR, Barrow CJ, Small DH, 'Acetycholinesterase is increased in mouse neuronal and astrocyte cultures after treatment with β-amyloid peptides', Brain Research: International Multidisciplinary Journal Devoted to Fundamental Research in The Brain Sciences, 965, (1-2) pp. 283-286. ISSN 0006-8993 (2003) [Refereed Article] DOI: 10.1016/S0006-8993(02)04159-8 [eCite] [Details] Citations: Scopus - 23Web of Science - 22 Tweet
2003	Small DH, Smith AI, 'Proteases and proteolytic processing in the nervous system: key targets for drug development', Journal of Neuroscience Research, 74, (3) pp. 339-341. ISSN 0360-4012 (2003) [Contribution to Refereed Journal] DOI: 10.1002/jnr.10782 [eCite] [Details] Tweet
2003	Subasinghe S, Unabia S, Barrow CJ, Mok SS, Aguilar MI, et al., 'Cholesterol is necessary both for the toxic effect of Aβ peptides on vascular smooth muscle cells and for Aβ binding to vascular smooth muscle cell membranes', Journal of Neurochemistry, 84, (3) pp. 471-479. ISSN 0022-3042 (2003) [Refereed Article] DOI: 10.1046/j.1471-4159.2003.01552.x [eCite] [Details] Citations: Scopus - 96Web of Science - 86 Tweet
2002	Fodero LR, Saez-Valero J, McLean CA, Martins RN, Beyreuther K, et al., 'Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition', Journal of Neurochemistry , 81, (3) pp. 441-448. ISSN 0022-3042 (2002) [Refereed Article] DOI: 10.1046/j.1471-4159.2002.00902.x [eCite] [Details] Citations: Scopus - 43Web of Science - 43 Tweet
2002	Mok SS, Turner BJ, Beyreuther K, Masters CL, Barrow CJ, et al., 'Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine', European Journal of Biochemistry: The Febs Journal, 269, (12) pp. 3014-3022. ISSN 0014-2956 (2002) [Refereed Article] DOI: 10.1046/j.1432-1033.2002.02976.x [eCite] [Details] Citations: Scopus - 38Web of Science - 34 Tweet
2001	Fodero LR, Saez-Valero J, Barquero MS, Marcos A, McLean CA, et al., 'Wheat germ agglutinin-binding glycoproteins are decreased in Alzheimer's disease cerebrospinal fluid', Journal of Neurochemistry, 79, (5) pp. 1022-1026. ISSN 0022-3042 (2001) [Refereed Article] DOI: 10.1046/j.1471-4159.2001.00640.x [eCite] [Details] Citations: Scopus - 38Web of Science - 35 Tweet
2001	Nunan J, Shearman MS, Checler F, Cappai R, Evin G, et al., 'The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase', European Journal of Biochemistry: The Febs Journal, 268, (20) pp. 5329-5336. ISSN 0014-2956 (2001) [Refereed Article] DOI: 10.1046/j.0014-2956.2001.02465.x [eCite] [Details] Citations: Scopus - 115Web of Science - 113 Tweet
2001	Saez-Valero J, Mok SS, Small DH, 'An unusually glycosylated form of acetylcholinesterase is a CSF biomarker for Alzheimer's disease', Acta Neurologica Scandinavica. Supplementum, 176 pp. 49-52 . ISSN 0065-1427 (2001) [Refereed Article] DOI: 10.1034/j.1600-0404.2000.00307.x [eCite] [Details] Citations: Web of Science - 16 Tweet
2001	Saez-Valero J, Small DH, 'Altered glycosylation of cerebrospinal fluid butyrylcholinesterase in Alzheimer's disease', Brain Research, 889, (1-2) pp. 247-250. ISSN 0006-8993 (2001) [Refereed Article] DOI: 10.1016/S0006-8993(00)03144-9 [eCite] [Details] Citations: Scopus - 16Web of Science - 14 Tweet
2001	Saez-Valero J, Small DH, 'Acetylcholinesterase and butyrylcholinesterase glycoforms are biomarkers of Alzheimer's disease', Journal of Alzheimer's Disease, 3, (3) pp. 323-328. ISSN 1387-2877 (2001) [Refereed Article] DOI: 10.3233/JAD-2001-3307 [eCite] [Details] Citations: Scopus - 14Web of Science - 11 Tweet
2001	Small DH, Mok SS, Bornstein JC, 'Alzheimer's disease and Aβ toxicity: from top to bottom', Nature Reviews Neuroscience, 2 pp. 595-598. ISSN 1471-003X (2001) [Refereed Article] [eCite] [Details]
2000	Postuma RB, He WL, Nunan J, Beyreuther K, Masters CL, et al., 'Substrate-bound beta-amyloid peptides inhibit cell adhesion and neurite outgrowth in primary neuronal cultures', Journal of Neurochemistry, 74, (3) pp. 1122-1130. ISSN 0022-3042 (2000) [Refereed Article] DOI: 10.1046/j.1471-4159.2000.741122.x [eCite] [Details] Citations: Scopus - 51Web of Science - 51 Tweet
2000	Saez-Valero J, Barquero MS, Marcos A, McLean CA, Small DH, 'Altered glycosylation of acetylcholinesterase in lumbar cerebrospinal fluid of patients with Alzheimer's disease', Journal of Neurology, Neurosurgery and Psychiatry, 69, (5) pp. 664-667. ISSN 0022-3050 (2000) [Refereed Article] DOI: 10.1136/jnnp.69.5.664 [eCite] [Details] Citations: Scopus - 37Web of Science - 39 Tweet
1999	Cappai R, Mok SS, Galatis D, Tucker DF, Henry A, et al., 'Recombinant human amyloid precursor-like protein 2 (APLP2) expressed in the yeast Pichia pastoris can stimulate neurite outgrowth', F E B S Letters: (Federation of European Biochemical Societies), 442, (1) pp. 95-98. ISSN 0014-5793 (1999) [Refereed Article] DOI: 10.1016/S0014-5793(98)01635-4 [eCite] [Details] Citations: Scopus - 50Web of Science - 50 Tweet
1999	Caswell MD, San Mok S, Henry A, Cappai R, Klug G, et al., 'The amyloid beta-protein precursor of Alzheimer's disease is degraded extracellularly by a Kunitz protease inhibitor domain-sensitive trypsin-like serine protease in cultures of chick sympathetic neurons', European Journal of Biochemistry: The Febs Journal, 266, (2) pp. 509-516. ISSN 0014-2956 (1999) [Refereed Article] DOI: 10.1046/j.1432-1327.1999.00886.x [eCite] [Details] Citations: Scopus - 14Web of Science - 13 Tweet
1999	Saez-Valero J, Sberna G, McLean CA, Small DH, 'Molecular isoform distribution and glycosylation of acetylcholinesterase are altered in brain and cerebrospinal fluid of patients with Alzheimer's disease', Journal of Neurochemistry, 72, (4) pp. 1600-1608. ISSN 0022-3042 (1999) [Refereed Article] DOI: 10.1046/j.1471-4159.1999.721600.x [eCite] [Details] Citations: Scopus - 98Web of Science - 99 Tweet
1999	Yang DS, Small DH, Seydel U, Smith JD, Hallmayer J, et al., 'Apolipoprotein E promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific manner', Neuroscience: An International Journal, 90, (4) pp. 1217-1226. ISSN 0306-4522 (1999) [Refereed Article] DOI: 10.1016/S0306-4522(98)00561-2 [eCite] [Details] Citations: Scopus - 96Web of Science - 97 Tweet
1998	Moir RD, Lynch T, Bush AI, Whyte S, Henry A, et al., 'Relative increase in Alzheimer's disease of soluble forms of cerebral A beta amyloid protein precursor containing the Kunitz protease inhibitory domain', Journal of Biological Chemistry, 273, (9) pp. 5013-5019. ISSN 0021-9258 (1998) [Refereed Article] DOI: 10.1074/jbc.273.9.5013 [eCite] [Details] Citations: Scopus - 89Web of Science - 93 Tweet
1998	Postuma RB, Martins RN, Cappai R, Beyreuther K, Masters CL, et al., 'Effects of the amyloid protein precursor of Alzheimer's disease and other ligands of the LDL receptor-related protein on neurite outgrowth from sympathetic neurons in culture', F E B S Letters: (Federation of European Biochemical Societies), 428, (1-2) pp. 13-16. ISSN 0014-5793 (1998) [Refereed Article] DOI: 10.1016/S0014-5793(98)00475-X [eCite] [Details] Citations: Scopus - 27Web of Science - 27 Tweet
1998	Sberna G, Saez-Valero J, Li QX, Czech C, Beyreuther K, et al., 'Acetylcholinesterase is increased in the brains of transgenic mice expressing the C-terminal fragment (CT100) of the beta-amyloid protein precursor of Alzheimer's disease', Journal of Neurochemistry, 71, (2) pp. 723-731. ISSN 0022-3042 (1998) [Refereed Article] DOI: 10.1046/j.1471-4159.1998.71020723.x [eCite] [Details] Citations: Web of Science - 98 Tweet
1997	Clarris HJ, Cappai R, Heffernan D, Beyreuther K, Masters CL, et al., 'Identification of heparin-binding domains in the amyloid precursor protein of Alzheimer's disease by deletion mutagenesis and peptide mapping', Journal of Neurochemistry, 68, (3) pp. 1164-1172. ISSN 0022-3042 (1997) [Refereed Article] DOI: 10.1046/j.1471-4159.1997.68031164.x [eCite] [Details] Citations: Web of Science - 69 Tweet
1997	Mok SS, Evin G, Li QX, Smith AI, Beyreuther K, et al., 'A novel metalloprotease in rat brain cleaves the amyloid precursor protein of Alzheimer's disease generating amyloidogenic fragments', Biochemistry, 36, (1) pp. 156-163. ISSN 0006-2960 (1997) [Refereed Article] DOI: 10.1021/bi961848w [eCite] [Details] Citations: Scopus - 18Web of Science - 17 Tweet
1997	Mok SS, Sberna G, Heffernan D, Cappai R, Galatis D, et al., 'Expression and analysis of heparin-binding regions of the amyloid precursor protein of Alzheimer's disease', F E B S Letters: (Federation of European Biochemical Societies), 415, (3) pp. 303-307. ISSN 0014-5793 (1997) [Refereed Article] DOI: 10.1016/S0014-5793(97)01146-0 [eCite] [Details] Citations: Scopus - 50Web of Science - 50 Tweet
1997	Saez-Valero J, Sberna G, McLean CA, Masters CL, Small DH, 'Glycosylation of acetylcholinesterase as diagnostic marker for Alzheimer's disease', The Lancet, 350 pp. 929. ISSN 0140-6736 (1997) [Letter or Note in Journal] [eCite] [Details]
1997	Sberna G, Saez-Valero J, Beyreuther K, Masters CL, Small DH, 'The amyloid beta-protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells', Journal of Neurochemistry, 69, (3) pp. 1177-1184. ISSN 0022-3042 (1997) [Refereed Article] DOI: 10.1046/j.1471-4159.1997.69031177.x [eCite] [Details] Citations: Web of Science - 113 Tweet
1996	Williamson TG, Mok SS, Henry A, Cappai R, Lander AD, et al., 'Secreted Glypican Binds to the Amyloid Precursor Protein of Alzheimer's Disease (APP) and Inhibits APP-induced Neurite Outgrowth', Journal of Biological Chemistry, 271, (49) pp. 31215-31221. ISSN 0021-9258 (1996) [Refereed Article] DOI: 10.1074/jbc.271.49.31215 [eCite] [Details] Citations: Scopus - 88Web of Science - 89 Tweet
1995	Brickman YG, Ford MD, Small DH, Bartlett PF, Nurcombe V, 'Heparan sulfates mediate the binding of basic fibroblast growth factor to a specific receptor on neural precursor cells', Journal of Biological Chemistry, 270, (42) pp. 24941-24948. ISSN 0021-9258 (1995) [Refereed Article] DOI: 10.1074/jbc.270.42.24941 [eCite] [Details] Citations: Scopus - 87Web of Science - 82 Tweet
1995	Evin G, Cappai R, Li QX, Culvenor JG, Small DH, et al., 'Candidate Gamma-Secretases in the Generation of the Carboxyl-Terminus of the Alzheimers-Disease Beta-A4 Amyloid - Possible Involvement Of Cathepsin-D', Biochemistry, 34, (43) pp. 14185-14192. ISSN 0006-2960 (1995) [Refereed Article] DOI: 10.1021/bi00043a024 [eCite] [Details] Citations: Scopus - 71Web of Science - 80 Tweet
1995	LePage RN, Fosang AJ, Fuller SJ, Murphy G, Evin G, et al., 'Gelatinase A possesses a beta-secretase-like activity in cleaving the amyloid protein precursor of Alzheimer's disease', F E B S Letters: (Federation of European Biochemical Societies), 377, (2) pp. 267-270. ISSN 0014-5793 (1995) [Refereed Article] DOI: 10.1016/0014-5793(95)01358-X [eCite] [Details] Citations: Scopus - 36Web of Science - 40 Tweet
1995	Li QX, Evin G, Small DH, Multhaup G, Beyreuther K, et al., 'Proteolytic Processing of Alzheimers-Disease Beta-A4 Amyloid Precursor Protein in Human Platelets', Journal of Biological Chemistry, 270, (23) pp. 14140-14147. ISSN 0021-9258 (1995) [Refereed Article] DOI: 10.1074/jbc.270.23.14140 [eCite] [Details] Citations: Scopus - 103Web of Science - 106 Tweet
1995	Small DH, 'A function for butyrylcholinesterase', Journal of Neurochemistry , 64, (1) pp. 466-467. ISSN 0022-3042 (1995) [Letter or Note in Journal] DOI: 10.1046/j.1471-4159.1995.64010466.x [eCite] [Details] Citations: Scopus - 6Web of Science - 6 Tweet
1995	Small DH, Reed G, Whitefield B, Nurcombe V, 'Cholinergic Regulation of Neurite Outgrowth from Isolated Chick Sympathetic Neurons in Culture', Journal of Neuroscience, 15, (1) pp. 144-151. ISSN 0270-6474 (1995) [Refereed Article] [eCite] [Details] Citations: Web of Science - 131
1995	Williamson TG, Nurcombe V, Beyreuther K, Masters CL, Small DH, 'Affinity Purification of Proteoglycans that bind to the Amyloid Protein Precursor of Alzheimers Disease', Journal of Neurochemistry, 65, (5) pp. 2201-2208. ISSN 0022-3042 (1995) [Refereed Article] DOI: 10.1046/j.1471-4159.1995.65052201.x [eCite] [Details] Citations: Scopus - 34Web of Science - 34 Tweet
1994	Small DH, Nurcombe V, Reed G, Clarris H, Moir R, et al., 'A Heparin-binding Domain in the Amyloid Protein Precursor of Alzheimer's Disease Is Involved in the Regulation of Neurite Outgrowth', Journal of Neuroscience, 14, (4) pp. 2117-2127. ISSN 0270-6474 (1994) [Refereed Article] [eCite] [Details] Citations: Web of Science - 325
1993	Bush AI, Multhaup G, Moir RD, Williamson TG, Small DH, et al., 'A novel zinc(II) binding site modulates the function of the beta-A4 amyloid protein precursor of Alzheimer's disease', Journal of Biological Chemistry, 268, (22) pp. 16109-16112. ISSN 0021-9258 (1993) [Refereed Article] [eCite] [Details] Citations: Web of Science - 256 Tweet
1993	Cheung NS, Small DH, Livett BG, 'An amyloid peptide beta-A4 25-35, mimics the function of substance P on modulation of nicotine-evoked secretion and desensitization in cultured bovine adrenal chromaffin cells', Journal of Neurochemistry, 60, (3) pp. 1163-1166. ISSN 0022-3042 (1993) [Refereed Article] DOI: 10.1111/j.1471-4159.1993.tb03270.x [eCite] [Details] Citations: Scopus - 33Web of Science - 35 Tweet
1992	Bush AI, Whyte S, Thomas LD, Williamson TG, Van Tiggelen CV, et al., 'An abnormality of plasma amyloid protein precursor in Alzheimer's disease', Annals of Neurology, 32, (1) pp. 57-65. ISSN 0364-5134 (1992) [Refereed Article] DOI: 10.1002/ana.410320110 [eCite] [Details] Citations: Scopus - 55Web of Science - 61 Tweet
1992	Milward EA, Papadopoulos R, Fuller SJ, Moir RD, Small D, et al., 'The Amyloid Protein Precursor of Alzheimer's Disease Is a Mediator of the Effects of Nerve Growth Factor on Neurite Outgrowth', Neuron, 9 pp. 129-137. ISSN 0896-6273 (1992) [Refereed Article] [eCite] [Details]
1992	Moir RD, Martins RN, Small DH, Bush AI, Milward EA, et al., 'Human brain beta-A4 amyloid protein precursor of Alzheimer's disease: purification and partial characterization. ', Journal of Neurochemistry, 59, (4) pp. 1490-1498. ISSN 0022-3042 (1992) [Refereed Article] DOI: 10.1111/j.1471-4159.1992.tb08465.x [eCite] [Details] Citations: Scopus - 48Web of Science - 54 Tweet
1992	Small DH, Nurcombe V, Moir R, Michaelson S, Monard D, et al., 'Association and Release of the Amyloid Protein Precursor of Alzheimer's Disease from Chick Brain Extracellular Matrix', Journal of Neuroscience, 12, (11) pp. 4143-4150. ISSN 0270-6474 (1992) [Refereed Article] [eCite] [Details] Citations: Web of Science - 84
1991	Small DH, Moir RD, Fuller S, Michaelson S, Bush AI, et al., 'A protease activity associated with acetylcholinesterase releases the membrane-bound form of the amyloid protein precursor of Alzheimer's disease', Biochemistry, 30, (44) pp. 10795-10799. ISSN 0006-2960 (1991) [Refereed Article] DOI: 10.1021/bi00108a027 [eCite] [Details] Citations: Scopus - 66Web of Science - 71 Tweet
1988	Kecorius E, Small DH, Livett BG, 'Characterization of a dipeptidyl aminopeptidase from bovine adrenal medulla', Journal of Neurochemistry, 50, (1) pp. 38-44 . ISSN 0022-3042 (1988) [Refereed Article] DOI: 10.1111/j.1471-4159.1988.tb13226.x [eCite] [Details] Citations: Scopus - 9Web of Science - 10 Tweet
1988	Small DH, Chubb IW, 'Identification of a trypsin-like site associated with acetylcholinesterase by affinity labelling with [H-3] diisopropyl fluorophosphate', Journal of Neurochemistry, 51, (1) pp. 69-74. ISSN 0022-3042 (1988) [Refereed Article] DOI: 10.1111/j.1471-4159.1988.tb04836.x [eCite] [Details] Citations: Scopus - 16Web of Science - 17 Tweet
1985	Small DH, Wurtman RJ, 'Binding of [H-3] serotonin to skeletal muscle actin', Journal of Neurochemistry, 45, (3) pp. 819-824. ISSN 0022-3042 (1985) [Refereed Article] DOI: 10.1111/j.1471-4159.1985.tb04067.x [eCite] [Details] Citations: Scopus - 10Web of Science - 12 Tweet
1985	Small DH, Wurtman RJ, 'Association of serotonin, dopamine, or noradrenaline with an actin-like component in pheochromocytoma (PC12) cells', Journal of Neurochemistry, 45, (3) pp. 825-831. ISSN 0022-3042 (1985) [Refereed Article] DOI: 10.1111/j.1471-4159.1985.tb04068.x [eCite] [Details] Citations: Scopus - 7Web of Science - 8 Tweet
1984	Small DH, Wurtman RJ, 'Serotonin binds specifically and saturably to an actin-like protein isolated from rat brain synaptosomes', National Academy of Sciences of The United States of America. Proceedings, 81, (3) pp. 959-963. ISSN 0027-8424 (1984) [Refereed Article] DOI: 10.1073/pnas.81.3.959 [eCite] [Details] Citations: Scopus - 21Web of Science - 23 Tweet
1982	Small DH, Carnegie PR, 'In Vivo Methylation of an Arginine in Chicken Myelin Basic Protein', Journal of Neurochemistry, 38, (1) pp. 184-190. ISSN 0022-3042 (1982) [Refereed Article] DOI: 10.1111/j.1471-4159.1982.tb10870.x [eCite] [Details] Citations: Scopus - 16Web of Science - 19 Tweet

Chapter in Book

(5 outputs)

Year	Citation	Altmetrics
2014	Aguilar M-I, Hou X, Losic D, Mechler AI, Martin LL, et al., 'Single-Molecule Imaging of Amyloid-β Protein (Aβ) of Alzheimer's Disease: From Single-Molecule Structures to Aggregation Mechanisms and Membrane Interactions', Bio-nanoimaging: Protein Misfolding & Aggregation, Elsevier, Uversky VN and Lyubchenko YL (ed), United States of America, pp. 47-56. ISBN 978-0-12-394431-3 (2014) [Research Book Chapter] DOI: 10.1016/B978-0-12-394431-3.00005-5 [eCite] [Details] Citations: Scopus - 1 Tweet
2012	Gasperini RJ, Klaver DW, Hou X, Aguilar MI, Small DH, 'Mechanisms of Transthyretin Aggregation and Toxicity', Protein Aggregation and Fibrillogenesis in Cerebral and Systematic Amyloid Disease, Subcellular Biochemistry 65, Springer, JR Harris (ed), Dordrecht, pp. 211-224. ISBN 978-94-007-5415-7 (2012) [Research Book Chapter] DOI: 10.1007/978-94-007-5416-4_9 [eCite] [Details] Citations: Scopus - 10 Co-authors: Gasperini RJ Tweet
2010	Hou X, Small DH, Aguilar MI, 'Surface Plasmon Resonance Spectroscopy in Determination of the Interactions Between Amyloid β Proteins (Aβ) and Lipid Membranes ', Methods in Molecular Biology: Surface Plasmon Resonance, Humana Press, NJ de Mol and MJE Fischer (ed), New York, pp. 225-235. ISBN 978-1-60761-669-6 (2010) [Other Book Chapter] DOI: 10.1007/978-1-60761-670-2_15 [eCite] [Details] Tweet
2007	Ng J, Aguilar MI, Small DH, 'Amyloid Toxicity, Synaptic Dysfunction, and the Biochemistry of Neurodegeneration in Alzheimer's Disease', Abeta Peptide and Alzheimer's Disease - Celebrating a Century of Research, Springer, Barrow CJ and Small DH (ed), London, pp. 93-101. ISBN 978-1-85233-961-6 (2007) [Research Book Chapter] [eCite] [Details]
2007	Small DH, Barrow CJ, 'A Brief Introduction to the History of the β-Amyloid Protein of Alzheimer's Disease', Abeta Peptide and Alzheimer's Disease, Springer, C.J Barrow & D.H Small (ed), London, pp. 1-4. ISBN 978-1-85233-961-6 (2007) [Research Book Chapter] [eCite] [Details]

Review

(3 outputs)

Year	Citation	Altmetrics
2008	Small DH, 'Network dysfunction in Alzheimer's disease: does synaptic scaling drive disease progression?', Trends in Molecular Medicine, 14, (3) pp. 103-108. (2008) [Substantial Review] DOI: 10.1016/j.molmed.2007.12.006 [eCite] [Details] Citations: Scopus - 76Web of Science - 66 Tweet
2008	Small DH, Klaver DW, Beckman M, 'Regulation of proBACE1 by glycosaminoglycans', Neurodegenerative Diseases, 5, (3-4) pp. 206-208. (2008) [Review Several Works] DOI: 10.1159/000113703 [eCite] [Details] Citations: Scopus - 6Web of Science - 4 Tweet
1981	Small DH, Carnegie PR, 'Myelopathy associated with vitamin B12 deficiency - new approaches to an old problem', Trends in Neuroscience, 4 pp. X-XI. (1981) [Review Several Works] [eCite] [Details]

Year

Citation

Altmetrics

2008

Small DH, 'Network dysfunction in Alzheimer's disease: does synaptic scaling drive disease progression?', Trends in Molecular Medicine, 14, (3) pp. 103-108. (2008) [Substantial Review]

DOI: 10.1016/j.molmed.2007.12.006 [eCite] [Details]

Citations: Scopus - 76Web of Science - 66

2008

Small DH, Klaver DW, Beckman M, 'Regulation of proBACE1 by glycosaminoglycans', Neurodegenerative Diseases, 5, (3-4) pp. 206-208. (2008) [Review Several Works]

DOI: 10.1159/000113703 [eCite] [Details]

Citations: Scopus - 6Web of Science - 4

1981

Small DH, Carnegie PR, 'Myelopathy associated with vitamin B12 deficiency - new approaches to an old problem', Trends in Neuroscience, 4 pp. X-XI. (1981) [Review Several Works]

[eCite] [Details]

Conference Publication

(14 outputs)

Year	Citation	Altmetrics
2014	Bolos M, Hu Y, Foa L, Young K, Small D, 'The role of Neurogenin2 in APP-stimulated neural stem or progenitor cell differentiation', 34th Annual Meeting Australasian Neuroscience Society, January, Adelaide, Australia (2014) [Conference Extract] [eCite] [Details] Co-authors: Bolos M; Hu Y; Foa L; Young K
2014	Bolos M, Hu Y, Foa L, Young KM, Small DH, 'APP regulates neural stem or progenitor cell differentiation through neurogenin 2 expresssion', Federation of European Neuroscience Societies, 5-9 July, Milan, Italy (2014) [Conference Extract] [eCite] [Details] Co-authors: Bolos M; Hu Y; Foa L; Young KM
2014	Hu Y, Bolos M, Dawkins E, Foa L, Young K, et al., 'Cystatin C regulates neural stem or progenitor cell proliferation (Poster)', 34th Annual Meeting Australasian Neuroscience Society, January, Adelaide, Australia (2014) [Conference Extract] [eCite] [Details] Co-authors: Hu Y; Bolos M; Dawkins E; Foa L; Young K
2013	Dawkins E, Vincent AJ, Gasperini R, Cui H, Young K, et al., 'A direct interaction of Aβ with anionic cellular lipids mediates binding to neurons (Poster)', 12th International Conference on Alzheimer's and Parkinson's Diseases, Florence, Italy (2013) [Conference Extract] [eCite] [Details] Co-authors: Dawkins E; Vincent AJ; Gasperini R; Cui H; Young K; Foa L
2013	Hu Y, Hung AC, Cui H, Dawkins E, Foa L, et al., 'APP stimulates neural stem/progenitor cell proliferation by increasing cystatin C secretion. (Poster)', 33rd Annual Meeting Australian Neuroscience Society, January, Melbourne, Australia (2013) [Conference Extract] [eCite] [Details] Co-authors: Hu Y; Hung AC; Cui H; Dawkins E; Foa L; Young KM
2012	Cui H, Hung AC, Freeman C, Narkowicz CK, Jacobson GA, et al., 'Effects of glycosaminoglycans on the level of β- and α-secretase and APP processing in Tg2576 primary cortical cells', APSN 2012, 29 September - 2 October, 2012, Kobe, Japan (2012) [Conference Extract] [eCite] [Details] Co-authors: Cui H; Hung AC; Narkowicz CK; Jacobson GA
2012	Cui H, Hung AC, Narkowicz CK, Jacobson GA, Small DH, 'Effects of glycosaminoglycans on the level of β- and α-secretase and APP processing in Tg2576 primary cortical cells', Australian Neuroscience Society Annual Meeting, 29 January - 1 February, 2012, Gold Coast, Australia (2012) [Conference Extract] [eCite] [Details] Co-authors: Cui H; Hung AC; Narkowicz CK; Jacobson GA
2012	Dawkins EA, Gasperini R, Vincent AJ, Foa LC, Small DH, 'Analysis of Aβ cell interactions and uptake in hippocampal culture', Proceedings of the 32nd Annual Meeting of the Australian Neuroscience Society, 29 January - 1 February 2012, Gold Coast, Australia, pp. 34. (2012) [Conference Extract] [eCite] [Details] Co-authors: Dawkins EA; Gasperini R; Vincent AJ; Foa LC
2011	Cui H, Hung AC, Klaver D, Narkowicz CK, Jacobson GA, et al., 'Effects of heparin and enoxaparin on APP processing and Aβ production in primary cortical neurons from Tg2576 mice', Australian Neuroscience Society 31st Annual Meeting, 31 January - 3 February, 2011, Auckland, New Zealand (2011) [Conference Extract] [eCite] [Details] Co-authors: Cui H; Hung AC; Klaver D; Narkowicz CK; Jacobson GA
2011	Hadrill CE, Gasperini RJ, Dickson TC, Foa LC, Small DH, 'Regulation of the cell adhesion molecule, L1CAM by the Aβ peptide of Alzheimer's Disease', Australian Neuroscience Society 31st Annual Meeting, 31 Jan - 3 Feb, Auckland, New Zealand (2011) [Conference Extract] [eCite] [Details] Co-authors: Hadrill CE; Gasperini RJ; Dickson TC; Foa LC
2011	Hoang T, Gasperini RJ, Cui H, Shepherd CE, Strickland DK, et al., 'Interaction of the receptor-associated protein (RAP) with APP and Aβ', Australian Neuroscience Society 31st Annual Meeting, 31 Jan - 3 Feb, Auckland, New Zealand (2011) [Conference Extract] [eCite] [Details] Co-authors: Hoang T; Gasperini RJ; Cui H; Foa LC
2011	Landowski LM, Gasperini RJ, Small DH, Taylor BVM, West AK, et al., 'Metallothionein I/II and metallothionein III induce growth cone chemotaxis via disparate mechanisms', Australian Neuroscience Society 31st Annual Meeting, 31 Jan - 3 Feb, Auckland, New Zealand (2011) [Conference Extract] [eCite] [Details] Co-authors: Landowski LM; Gasperini RJ; Taylor BVM; West AK; Foa LC
2011	Mitchell C, Gasperini RJ, Small DH, Foa LC, 'STIM1 is necessary for regulation of growth cone motility', Australian Neuroscience Society 31st Annual Meeting, 31 Jan - 3 Feb, Auckland, New Zealand (2011) [Conference Extract] [eCite] [Details] Co-authors: Gasperini RJ; Foa LC
2011	Small DH, Klaver D, Liu S, Cui H, Hoang T, et al., 'Disruption of protein trafficking in Alzheimer's Disease: APP, Aβ and AMPA receptors', Australian Neuroscience Society 31st Annual Meeting, 31 Jan - 3 Feb, Auckland, New Zealand (2011) [Conference Extract] [eCite] [Details] Co-authors: Klaver D; Liu S; Cui H; Hoang T; Gasperini RJ; Foa LC

Entry

(1 outputs)

Year	Citation	Altmetrics
2016	Southam K, Stennard FA, Small DH, 'App', Encyclopedia of Signaling Molecules, S Choi (ed), pp. 1-8 (2016) [Entry] DOI: 10.1007/978-1-4614-6438-9_101532-1 [eCite] [Details] Co-authors: Southam K; Stennard FA Tweet

Year

Citation

Altmetrics

2016

Southam K, Stennard FA, Small DH, 'App', Encyclopedia of Signaling Molecules, S Choi (ed), pp. 1-8 (2016) [Entry]

DOI: 10.1007/978-1-4614-6438-9_101532-1 [eCite] [Details]

Co-authors: Southam K; Stennard FA

Grants & Funding

Prof Smalls outstanding contribution to the field has been well recognised through continuous NHMRC project/program grant funding since 1990.

Funding Summary

Number of grants

Total funding

$5,148,541

Projects

Are microglia the villains of AB toxicity in Alzheimer's disease (2015 - 2016)$110,000

Description: The project will create new knowledge into the role that microglia play in the development of Alzheimer's disease.
Funding: Dementia Australia Research Foundation Ltd ($110,000)
Scheme: Fellowship-Postdoctoral Fellowship in Dementia
Administered By: University of Tasmania
Research Team: Southam K; Small DH; Vincent AJ
Period: 2015 - 2016

Establishment of a digital transmission electron microscopy facility (2014)$380,000

Description: Transmission electron microscopy is a fundamental tool for the study of biological systems at the ultrastructural level. Tasmania has only one, aged and barely functioning electron microscopy facility. This proposal is to establish a State-wide facility that will be accessible to a range of biological researchers across Tasmania, as well as the CSIRO and Antarctic Division. The proposed instrument will be established in new purpose-built laboratory space in the UTAS Medical Sciences Precinct, and will be supported by the Central Science Laboratory. The instrument will revitalise cellular research in Tasmania, and provide additional insights and outcomes related to the study of intracellular features in a diverse range of systems and models.
Funding: Australian Research Council ($380,000)
Scheme: Grant-Linkage Infrastructure
Administered By: University of Tasmania
Research Team: Vickers JC; Small DH; Nowak BF; Hilder EF; Hallegraeff GM
Year: 2014
Grant Reference: LE140100174

Transient receptor potential channels, calcium and Alzheimer's disease (2013 - 2015)$390,758

Funding: National Health & Medical Research Council ($390,758)
Scheme: Grant-Project
Administered By: University of Tasmania
Research Team: Small DH; Foa LC; Vickers JC; Parkington H; Coleman H
Period: 2013 - 2015
Grant Reference: 1042566

Establishing a state-of-the-art 'Live Cell Recording and Imaging Facility' at Menzies Research Institute Tasmania (2013)$22,000

Funding: Rebecca L Cooper Medical Research Foundation ($22,000)
Scheme: Grant
Administered By: University of Tasmania
Research Team: Young K; Small DH; Foa LC; Dickson TC
Year: 2013

The role of store-operated calcium entry in neuronal development (2012 - 2014)$341,175

Funding: National Health & Medical Research Council ($341,175)
Scheme: Grant-Project
Administered By: University of Tasmania
Research Team: Foa LC; Small DH; Gell DA
Period: 2012 - 2014
Grant Reference: 1024145

Understanding the cause of Alzheimer's disease (2012)$177,325

Funding: National Health & Medical Research Council ($177,325)
Scheme: Grant-Dementia Seed Funding
Administered By: University of Tasmania
Research Team: Small DH; Foa LC; Vickers JC
Year: 2012
Grant Reference: 1020843

Biochemical studies on amyloid diseases (2011 - 2015)$630,505

Funding: National Health & Medical Research Council ($630,505)
Scheme: Fellowship-Research
Administered By: University of Tasmania
Research Team: Small DH
Period: 2011 - 2015
Grant Reference: 1002473

Oligodendrocyte Progenitor Cells - A new target for Alzheimer's Disease Treatment (2011 - 2013)$442,777

Funding: Bupa Foundation/Alzheimer's Society ($442,777)
Scheme: Grant-Specialist Research
Administered By: University of Tasmania
Research Team: Young K; Small DH
Period: 2011 - 2013

Multidimensional analysis of biomarkers for the early detection of Alzheimer's disease using in vivo MRS (2011)$45,600

Funding: The Mason Foundation ($45,600)
Scheme: Grant-Judith Jane Mason & Harold Stannett Williams
Administered By: University of Tasmania
Research Team: Small DH; Edwards LM; Foa LC
Year: 2011

The receptor-associated protein (RAP) as a molecular chaperone for the amyloid protein (Abeta) of Alzheimer's disease (2010 - 2012)$388,526

Funding: National Health & Medical Research Council ($388,526)
Scheme: Grant-Project
Administered By: University of Tasmania
Research Team: Small DH; Aguilar M; Shepherd CE; Strickland D
Period: 2010 - 2012
Grant Reference: 605530

How amyloid causes neurodegeneration: the role of transthyretin in familial amyloidotic polyneuropathy (2009 - 2011)$594,375

Funding: National Health & Medical Research Council ($594,375)
Scheme: Grant-Project
Administered By: University of Tasmania
Research Team: Small DH; Parkington H; Cheung NS; Aguilar M; Coleman H
Period: 2009 - 2011
Grant Reference: 544920

Regulation of the beta-secretase (BACE1) by glycosaminoglycans (2008 - 2010)$539,250

Funding: National Health & Medical Research Council ($539,250)
Scheme: Grant-Project
Administered By: University of Tasmania
Research Team: Small DH; Vickers JC; West AK
Period: 2008 - 2010
Grant Reference: 490031

Establishment of a Confocal/multiphoton Microscope for Imaging of Living Systems (2008)$300,000

Funding: Australian Research Council ($300,000)
Scheme: Grant-Linkage Infrastructure
Administered By: University of Tasmania
Research Team: Vickers JC; Foote SJ; Small DH; Walters EH; Hallegraeff GM; West AK; Chung RS; Woods GM; Dickson TC; Nowak BF; Bolch CJS
Year: 2008
Grant Reference: LE0882701

David Small Research Fellowship - SRF B (2005 - 2010)$786,250

Funding: National Health & Medical Research Council ($786,250)
Scheme: Fellowship-Research
Administered By: National Health & Medical Research Council
Research Team: Small DH
Period: 2005 - 2010
Grant Reference: 334035

Research Supervision

Prof Small has successfully supervised more than 12 PhD candidates and over 20 honours students to completion.

Completed

Degree	Title	Completed
PhD	Role of Amyloid Precursor Protein in Neural Stem/Progenitor Cell Proliferation and Differentiation Candidate: Yanling Hu	2016
PhD	Role of Phosphoinositides in the Biology of the Amyloid Precursor Protein Candidate: Edgar Adam Henry Dawkins	2014
PhD	STIM1 Mediates Multiple Signalling Pathways in Neuronal Growth Cones Candidate: Camilla Bessie Mitchell	2013
PhD	Studies on the Use of Glycosaminoglycans for the Treatment of Alzheimer's Disease Candidate: Hao Cui	2012
Masters	Role of the 39-kDa Receptor-Associated Protein (RAP) in Alzheimer's Disease Candidate: Thanh Hoang	2012