Profiles

Dawn Aitken

Associate Professor Dawn Aitken

Dawn Aitken

Principal Research Fellow
Menzies Institute for Medical Research

Room 363c , MS2

+61 3 6226 7769 (phone)

Dawn.Aitken@utas.edu.au

Nearly one in ten Australians suffers from osteoarthritis, a chronic condition that affects the joints (e.g. hips, knees, hands, back or ankles).

Associate Professor Dawn Aitken leads a program of research which centres on improving our understanding and management of osteoarthritis. Osteoarthritis is a painful, disabling, and costly condition that affects the joints in our body including the knees, hips and hands.

Dawn is particularly interested in the role of exercise in the prevention and management of osteoarthritis. She works closely with clinicians to help improve the conservative (non-surgical) management of osteoarthritis and has published numerous papers on the relationship between physical activity and osteoarthritis. Her work has been used to develop new physical activity guidelines for people with chronic diseases by the US Department of Health and Human Services and he she has contributed to Australian policy white papers.

Dawn also leads or collaborates on a number of major clinical drug trials aimed at slowing down – or halting – the progression of osteoarthritis. Her team conducted the largest study in the world to examine whether the commonly used osteoporosis medication – zoledronic acid, can be used to treat knee osteoarthritis. The study found that zoledronic acid did not slow cartilage loss or improve knee pain. It provides definitive, high-quality evidence that zoledronic acid should not be used to treat knee osteoarthritis. This work was published in JAMA (The Journal of the American Medical Association) in April 2020. She has also worked on turmeric and fish oil for knee osteoarthritis, adalimumab for hand osteoarthritis, and zoledronic acid and denosumab for back pain.

Associate Professor Dawn Aitken is Head of the Musculoskeletal Health and Disease Research Group at the Menzies Institute for Medical Research. She is currently supported by a NHMRC/MRFF Career Development Fellowship. She completed her PhD in 2011 at the University of Tasmania examining early changes that occur in knee osteoarthritis. Before this she completed a Bachelor of Science, with Honours in Human Kinetics, at the University of Ottawa, Canada.

Career summary

Qualifications

PhD, University of Tasmania, Australia. 2011 Thesis: The role of subchrondral bone in osteoarthritis
Bachelor of Biotechnology (1st Class Hons), University of Tasmania, Australia. 2007
Bachelor of Science (Human Kinetics), University of Ottawa, Canada. 2006

View more on AssocProf Dawn Aitken in WARP

Expertise

Osteoarthritis
Exercise/physical activity
Clinical trials
Pain
Epidemiology
Magnetic resonance imaging (MRI)

Research Themes

Dr Aitken's research is strongly aligned with the University's key theme of Better Health.

Awards

Award Highlights

2020 Young Tall Poppy (Tasmania)
2018 ASBMR Rising Star Award ($60,000 USD)
2018 Tasmanian STEM Young Researcher of the Year Award ($5,000)
2018 ANZBMS Kaye Ibbertson Award ($1,000) for the 5 best papers published in the last 5 years, in the field of bone and mineral research.
2017 ESCEO-Eli Lilly Scholarship. Top rated abstract award at the 2017 World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases ($3,200)

Fields of Research

Rheumatology and arthritis (320223)
Epidemiology (420299)
Physiotherapy (420106)
Geriatrics and gerontology (320210)
Pain (320218)
Aged health care (420301)
Orthopaedics (320216)
Health promotion (420603)
Primary health care (420319)
Podiatry (420107)
Traditional, complementary and integrative medicine (420899)
Health and community services (420305)
Health counselling (420307)
Sports science and exercise (420799)
Clinical sciences (320299)
Health services and systems (420399)
Nutritional epidemiology (420208)
Multimorbidity (420314)
Zoology (310999)
Autonomic nervous system (320901)
Nutritional science (321004)
Medical biotechnology diagnostics (incl. biosensors) (320602)
Behavioural epidemiology (420201)
Implementation science and evaluation (420312)
Health economics (380108)
Public health nutrition (321005)
Sports medicine (320225)
Endocrinology (320208)
Clinical pharmacology and therapeutics (321402)
Medical biochemistry - lipids (320504)
Biomechanics (420701)
Health equity (420602)
Cellular immunology (320404)
Solid tumours (321111)
Health management (420309)
Allied health and rehabilitation science (420199)
Exercise physiology (420702)
Rehabilitation (420109)

Research Objectives

Clinical health (200199)
Treatment of human diseases and conditions (200105)
Diagnosis of human diseases and conditions (200101)
Efficacy of medications (200102)
Health related to ageing (200502)
Allied health therapies (excl. mental health services) (200301)
Human pain management (200103)
Determinants of health (200201)
Evaluation of health outcomes (200202)
Behaviour and health (200401)
Health education and promotion (200203)
Primary care (200310)
Public health (excl. specific population health) (200499)
Preventive medicine (200412)
Health system performance (incl. effectiveness of programs) (200206)
Prevention of human diseases and conditions (200104)
Overweight and obesity (200411)
Expanding knowledge in the health sciences (280112)
Disability and functional capacity (200403)
Nutrition (200410)
Community health care (200302)
Teaching and curriculum (160399)
Health policy evaluation (200205)

Publications

Total publications

120

Highlighted publications

(8 outputs)

Year	Type	Citation
2020	Journal Article	Cai G, Aitken D, Laslett LL, Pelletier J-P, Martel-Pelletier J, et al., 'Effect of intravenous zoledronic acid on tibiofemoral cartilage volume among patients with knee osteoarthritis with bone marrow lesions: a randomized clinical trial', JAMA - Journal of the American Medical Association, 323, (15) pp. 1456-1466. ISSN 0098-7484 (2020) [Refereed Article] DOI: 10.1001/jama.2020.2938 [eCite] [Details] Citations: Scopus - 43Web of Science - 42 Co-authors: Cai G; Laslett LL; Antony B; Blizzard L; Winzenberg T; Jones G Tweet
2020	Journal Article	Wang Z, Jones G, Winzenberg T, Cai G, Laslett LL, et al., 'Effectiveness of Curcuma longa extract for the treatment of symptoms and effusion-synovitis of knee osteoarthritis : a randomized trial', Annals of Internal Medicine, 173, (11) pp. 861-869. ISSN 0003-4819 (2020) [Refereed Article] DOI: 10.7326/M20-0990 [eCite] [Details] Citations: Scopus - 47Web of Science - 42 Co-authors: Jones G; Winzenberg T; Cai G; Laslett LL; Singh A; Ding C; Antony B Tweet
2018	Journal Article	Aitken D, Laslett LL, Pan F, Haugen IK, Otahal P, et al., 'A randomised double-blind placebo-controlled crossover trial of HUMira (adalimumab) for erosive hand OsteoaRthritis - the HUMOR trial', Osteoarthritis and Cartilage, 26, (7) pp. 880-887. ISSN 1063-4584 (2018) [Refereed Article] DOI: 10.1016/j.joca.2018.02.899 [eCite] [Details] Citations: Scopus - 79Web of Science - 74 Co-authors: Laslett LL; Pan F; Otahal P; Jones G Tweet
2018	Journal Article	Balogun S, Aitken D, Winzenberg T, Wills K, Scott D, et al., 'Longitudinal associations of serum 25-hydroxyvitamin-D, physical activity, and knee pain and dysfunction with muscle loss in community-dwelling older adults', Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 73, (4) pp. 526-531. ISSN 1079-5006 (2018) [Refereed Article] DOI: 10.1093/gerona/glx157 [eCite] [Details] Citations: Scopus - 9Web of Science - 8 Co-authors: Balogun S; Winzenberg T; Wills K; Callisaya M; Jones G Tweet
2018	Journal Article	Cai G, Laslett LL, Aitken D, Halliday A, Pan F, et al., 'Effect of Zoledronic Acid and Denosumab in patients with low back pain and modic change: A proof-of-principle trial', Journal of Bone and Mineral Research, 33, (5) pp. 773-782. ISSN 0884-0431 (2018) [Refereed Article] DOI: 10.1002/jbmr.3376 [eCite] [Details] Citations: Scopus - 26Web of Science - 23 Co-authors: Cai G; Laslett LL; Pan F; Otahal P; Winzenberg TM; Jones G Tweet
2018	Journal Article	Munugoda IP, Wills K, Cicuttini F, Graves SE, Lorimer M, et al., 'The association between ambulatory activity, body composition and hip or knee joint replacement due to osteoarthritis: a prospective cohort study', Osteoarthritis and Cartilage, 26, (5) pp. 671-679. ISSN 1063-4584 (2018) [Refereed Article] DOI: 10.1016/j.joca.2018.02.895 [eCite] [Details] Citations: Scopus - 17Web of Science - 15 Co-authors: Munugoda IP; Wills K; Jones G; Callisaya ML Tweet
2013	Journal Article	Dore DA, Winzenberg TM, Ding C, Otahal P, Pelletier JP, et al., 'The association between objectively measured physical activity and knee structural change using MRI', Annals of the Rheumatic Diseases, 72, (7) pp. 1170-1175. ISSN 0003-4967 (2013) [Refereed Article] DOI: 10.1136/annrheumdis-2012-201691 [eCite] [Details] Citations: Scopus - 78Web of Science - 79 Co-authors: Winzenberg TM; Ding C; Otahal P; Jones G Tweet
2012	Journal Article	Laslett LL, Dore DA, Quinn SJ, Boon P, Ryan E, et al., 'Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial', Annals of the Rheumatic Diseases, 71, (8) pp. 1322-1328. ISSN 0003-4967 (2012) [Refereed Article] DOI: 10.1136/annrheumdis-2011-200970 [eCite] [Details] Citations: Scopus - 208Web of Science - 190 Co-authors: Laslett LL; Boon P; Winzenberg TM; Jones G Tweet

Journal Article

(111 outputs)

Year	Citation	Altmetrics
2023	Drummen SJJ, Balogun S, Lahham A, Bennell K, Hinman RS, et al., 'A pilot randomized controlled trial evaluating outdoor community walking for knee osteoarthritis: walk', Clinical rheumatology pp. 1-13. ISSN 1434-9949 (2023) [Refereed Article] DOI: 10.1007/s10067-022-06477-5 [eCite] [Details] Co-authors: Drummen SJJ; Balogun S; Callisaya M; Cai G; Otahal P; Winzenberg T; Eathakkattu Antony BS; Munugoda IP; Jones Graeme Tweet
2023	Wang Zhiqiang, Winzenberg T, Singh Ambrish, Aitken D, Blizzard L, et al., 'Effect of Curcuma longa extract on serum inflammatory markers and MRI-based synovitis in knee osteoarthritis: secondary analyses from the CurKOA randomised trial', Phytomedicine : international journal of phytotherapy and phytopharmacology, 109 Article 154616. ISSN 0944-7113 (2023) [Refereed Article] DOI: 10.1016/j.phymed.2022.154616 [eCite] [Details] Co-authors: Winzenberg T; Singh Ambrish; Blizzard L; Eathakkattu Antony BS Tweet
2022	Bonakdari H, Pelletier JP, Blanco FJ, Rego-Perez I, Duran-Sotuela A, et al., 'Single nucleotide polymorphism genes and mitochondrial DNA haplogroups as biomarkers for early prediction of knee osteoarthritis structural progressors: use of supervised machine learning classifiers', BMC Medicine, 20, (1) Article 316. ISSN 1741-7015 (2022) [Refereed Article] DOI: 10.1186/s12916-022-02491-1 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Jones G Tweet
2022	Cai G, Jones G, Cicuttini FM, Wluka AE, Wang Y, et al., 'Study protocol for a randomised controlled trial of diacerein versus placebo to treat knee osteoarthritis with effusion-synovitis (DICKENS)', Trials, 23, (1) Article 768. ISSN 1745-6215 (2022) [Refereed Article] DOI: 10.1186/s13063-022-06715-w [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Cai G; Jones G; Antony B; de Graaff B; Thompson M; Winzenberg T; Buttigieg K Tweet
2022	Cai G, Laslett LL, Bowes MA, Conaghan PG, Cicuttini F, et al., 'Effect of zoledronic acid with or without methylprednisolone on 3D bone area and bone shape in patients with symptomatic knee osteoarthritis: A post-hoc analysis of the ZAP2 trial', Seminars in Arthritis and Rheumatism, 56 Article 152054. ISSN 0049-0172 (2022) [Refereed Article] DOI: 10.1016/j.semarthrit.2022.152054 [eCite] [Details] Co-authors: Cai G; Laslett LL; Winzenberg T; Jones G Tweet
2022	Liu M, Huang Y, Zhang H, Aitken D, Nevitt MC, et al., 'Restricting branched-chain amino acids within a high-fat diet prevents obesity', Metabolites, 12, (4) Article 334. ISSN 2218-1989 (2022) [Refereed Article] DOI: 10.3390/metabo12040334 [eCite] [Details] Citations: Scopus - 4Web of Science - 3 Co-authors: Jones G Tweet
2022	Ma C, Aitken D, Wu F, Squibb K, Cicuttini F, et al., 'Association between radiographic hand osteoarthritis and bone microarchitecture in a population-based sample', Arthritis Research and Therapy, 24, (1) pp. 1-10. ISSN 1478-6362 (2022) [Refereed Article] DOI: 10.1186/s13075-022-02907-6 [eCite] [Details] Co-authors: Ma C; Wu F; Squibb K; Jones G Tweet
2022	Munugoda IP, Brennan-Olsen SL, Wills K, Cai G, Graves SE, et al., 'The association between socioeconomic status and joint replacement of the hip and knee: a population-based cohort study of older adults in Tasmania', Internal Medicine Journal, 52, (2) pp. 265-271. ISSN 1444-0903 (2022) [Refereed Article] DOI: 10.1111/imj.15066 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Munugoda IP; Wills K; Cai G; Callisaya ML; Jones G Tweet
2022	Singh A, Aitken D, Moonaz S, Palmer AJ, Blizzard CL, et al., 'A Randomised Controlled Trial of YOGa and Strengthening Exercise for Knee OsteoArthritis: Protocol for a Comparative Effectiveness Trial (YOGA Trial)', Journal of Functional Morphology and Kinesiology, 7, (4) Article 84. ISSN 2411-5142 (2022) [Refereed Article] DOI: 10.3390/jfmk7040084 [eCite] [Details] Co-authors: Singh A; Palmer AJ; Blizzard CL; Ding C; Drummen SJ; Jones Graeme; Anthony B Tweet
2022	Sutton L, Jose K, Hansen E, Laslett L, Makin K, et al., 'Navigating the maze of osteoarthritis treatment: A qualitative study exploring the experience of individuals with osteoarthritis in Tasmania, Australia', Musculoskeletal Care pp. 1-8. ISSN 1478-2189 (2022) [Refereed Article] DOI: 10.1002/msc.1700 [eCite] [Details] Co-authors: Sutton L; Jose K; Hansen E; Laslett L; Makin K; Winzenberg T; Balogun S Tweet
2022	Sutton LP, Lahham A, Jose K, Moore MN, Antony B, et al., 'Feasibility of parkrun' for people with knee osteoarthritis: A mixed methods pilot study', Osteoarthritis and Cartilage Open, 4, (2) Article 100269. ISSN 2665-9131 (2022) [Refereed Article] DOI: 10.1016/j.ocarto.2022.100269 [eCite] [Details] Co-authors: Sutton LP; Jose K; Moore MN; Antony B; Cleland V; Winzenberg T; Jones G Tweet
2022	Wang Zhiqiang, Singh Ambrish, Jones Graeme, Aitken D, Laslett LL, et al., 'Boswellia for osteoarthritis (Protocol)', Cochrane Database of Systematic Reviews, 2022, (10) pp. 1-16. ISSN 1469-493X (2022) [Refereed Article] DOI: 10.1002/14651858.CD014969 [eCite] [Details] Co-authors: Singh Ambrish; Jones Graeme; Laslett LL; Ding C; Antony B Tweet
2022	Werdyani S, Aitken D, Gao Z, Liu M, Randell EW, et al., 'Metabolomic signatures for the longitudinal reduction of muscle strength over 10 years', Skeletal Muscle, 12, (1) pp. 1-15. ISSN 2044-5040 (2022) [Refereed Article] DOI: 10.1186/s13395-022-00286-9 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Jones G Tweet
2022	Xie Z, Aitken D, Liu M, Lei G, Jones Graeme, et al., 'Serum Metabolomic Signatures for Knee Cartilage Volume Loss over 10 Years in Community-Dwelling Older Adults', Life, 12, (6) Article 869. ISSN 2075-1729 (2022) [Refereed Article] DOI: 10.3390/life12060869 [eCite] [Details] Co-authors: Jones Graeme Tweet
2021	Aitken D, Balogun S, Foong Y, Humphries D, Laslett L, et al., 'Clinical relevance of MRI knee abnormalities in Australian rules football players: a longitudinal study', BMJ Open Sport & Exercise Medicine, 7, (3) ISSN 2055-7647 (2021) [Refereed Article] DOI: 10.1136/bmjsem-2021-001097 [eCite] [Details] Co-authors: Foong Y; Laslett L; Pitchford N; Khan H; Jones G; Winzenberg T Tweet
2021	Balogun S, Aitken D, Wu F, Scott D, Jones G, et al., 'Linear and nonlinear associations between physical activity, body composition, and multimorbidity over 10 years among community-dwelling older adults ', Journals of Gerontology. Series A: Biological Sciences and Medical Sciences, 76, (11) pp. 2015-2020. ISSN 1079-5006 (2021) [Refereed Article] DOI: 10.1093/gerona/glab086 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Balogun S; Wu F; Jones G; Winzenberg TM Tweet
2021	Gandham A, Zengin A, Bonham MP, Brennan-Olsen SL, Aitken D, et al., 'Associations between socioeconomic status and obesity, sarcopenia, and sarcopenic obesity in community-dwelling older adults: The Tasmanian Older Adult Cohort Study', Experimental Gerontology, 156 pp. 1-7. ISSN 0531-5565 (2021) [Refereed Article] DOI: 10.1016/j.exger.2021.111627 [eCite] [Details] Citations: Web of Science - 1 Co-authors: Winzenberg TM; Jones G Tweet
2021	Sutton L, Jose K, Betzold A, Hansen E, Laslett L, et al., 'Understanding the management of osteoarthritis in Australia: a qualitative study of GPs and orthopaedic surgeons in Tasmania, Australia', Osteoarthritis and Cartilage Open, 3, (4) Article 100218. ISSN 2665-9131 (2021) [Refereed Article] DOI: 10.1016/j.ocarto.2021.100218 [eCite] [Details] Co-authors: Sutton L; Jose K; Betzold A; Hansen E; Laslett L; Makin J; Winzenberg T Tweet
2021	Thompson M, Aitken D, Balogun S, Cicuttini F, Jones G, 'Population Vitamin D Stores Are Increasing in Tasmania, and This Is Associated with Less BMD Loss over 10 Years', Journal of Clinical Endocrinology and Metabolism, 106, (8) pp. E2995-E3004. ISSN 0021-972X (2021) [Refereed Article] DOI: 10.1210/clinem/dgab197 [eCite] [Details] Citations: Scopus - 1 Co-authors: Thompson M; Balogun S; Jones G Tweet
2021	Zhao T, Winzenberg T, Aitken D, de Graaff B, Ahmad H, et al., 'The impact of comorbidities on health-related quality of life of people with osteoarthritis over 10 years', Rheumatology, 61, (1) pp. 139-145. ISSN 1462-0332 (2021) [Refereed Article] DOI: 10.1093/rheumatology/keab358 [eCite] [Details] Co-authors: Zhao T; Winzenberg T; de Graaff B; Ahmad H; Jones Graeme; Palmer AJ Tweet
2021	Zheng S, Tu L, Cicuttini F, Zhu Z, Han W, et al., 'Depression in patients with knee osteoarthritis: risk factors and associations with joint symptoms', BMC Musculoskeletal Disorders, 22, (1) Article 40. ISSN 1471-2474 (2021) [Refereed Article] DOI: 10.1186/s12891-020-03875-1 [eCite] [Details] Citations: Scopus - 23Web of Science - 21 Co-authors: Zheng S; Zhu Z; Han W; Antony B; Winzenberg T; Blizzard L; Jones G; Ding C Tweet
2021	Zheng S, Wu F, Winzenberg T, Cicuttini F, Wluka AE, et al., 'The cross-sectional and longitudinal associations of dietary patterns with knee symptoms and MRI detected structure in patients with knee osteoarthritis', Osteoarthritis and Cartilage: Journal of The Osteoarthritis Research Society International, 29, (4) pp. 527-535. ISSN 1063-4584 (2021) [Refereed Article] DOI: 10.1016/j.joca.2020.12.023 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Zheng S; Wu F; Winzenberg T; Antony B; Blizzard L; Ding C Tweet
2020	Ahedi H, Aitken D, Blizzard L, Cicuttini F, Jones G, 'Quantification of hip effusion-synovitis and its cross-sectional and longitudinal associations with hip pain, MRI findings and early radiographic hip OA', BMC Musculoskeletal Disorders, 21, (1) Article 533. ISSN 1471-2474 (2020) [Refereed Article] DOI: 10.1186/s12891-020-03532-7 [eCite] [Details] Citations: Scopus - 9Web of Science - 9 Co-authors: Ahedi H; Blizzard L; Jones G Tweet
2020	Balogun S, Scott D, Cicuttini F, Jones G, Aitken D, 'Longitudinal study of the relationship between physical activity and knee pain and functional limitation in community-dwelling older adults', Archives of Gerontology and Geriatrics, 90 Article 104101. ISSN 0167-4943 (2020) [Refereed Article] DOI: 10.1016/j.archger.2020.104101 [eCite] [Details] Citations: Scopus - 7Web of Science - 7 Co-authors: Balogun S; Jones G Tweet
2020	Balogun SA, Graves SE, Lorimer M, Cicuttini F, Scott D, et al., 'Do older adults with low muscle mass or strength, in the presence of obesity, have an increased risk of joint replacement over 13 Years?', Calcified Tissue International, 107, (1) pp. 10-17. ISSN 0171-967X (2020) [Refereed Article] DOI: 10.1007/s00223-020-00698-z [eCite] [Details] Citations: Scopus - 2Web of Science - 2 Co-authors: Balogun SA; Scott D; Jones G Tweet
2020	Cai G, Aitken D, Laslett LL, Hill C, Wluka AE, et al., 'The association between change in bone marrow lesion size and change in tibiofemoral cartilage volume and knee symptoms', Rheumatology, (November) pp. 1-10. ISSN 1462-0324 (2020) [Refereed Article] DOI: 10.1093/rheumatology/keaa716 [eCite] [Details] Citations: Scopus - 4Web of Science - 5 Co-authors: Cai G; Laslett LL; Jones G Tweet
2020	Cai G, Aitken D, Laslett LL, Pelletier J-P, Martel-Pelletier J, et al., 'Effect of intravenous zoledronic acid on tibiofemoral cartilage volume among patients with knee osteoarthritis with bone marrow lesions: a randomized clinical trial', JAMA - Journal of the American Medical Association, 323, (15) pp. 1456-1466. ISSN 0098-7484 (2020) [Refereed Article] DOI: 10.1001/jama.2020.2938 [eCite] [Details] Citations: Scopus - 43Web of Science - 42 Co-authors: Cai G; Laslett LL; Antony B; Blizzard L; Winzenberg T; Jones G Tweet
2020	Cai G, Cicuttini F, Aitken D, Laslett LL, Zhu Z, et al., 'Comparison of radiographic and MRI osteoarthritis definitions and their combination for prediction of tibial cartilage loss, knee symptoms and total knee replacement: a longitudinal study', Osteoarthritis and Cartilage, 28 pp. 1062-1070. ISSN 1063-4584 (2020) [Refereed Article] DOI: 10.1016/j.joca.2020.04.017 [eCite] [Details] Citations: Scopus - 5Web of Science - 4 Co-authors: Cai G; Laslett LL; Winzenberg T; Jones G Tweet
2020	Cai G, Keen HI, Host LV, Aitken D, Laslett LL, et al., 'Once-yearly zoledronic acid and change in abdominal aortic calcification over 3 years in postmenopausal women with osteoporosis: results from the HORIZON Pivotal Fracture Trial', Osteoporosis International, 31, (9) pp. 1741-1747. ISSN 0937-941X (2020) [Refereed Article] DOI: 10.1007/s00198-020-05430-z [eCite] [Details] Citations: Scopus - 7Web of Science - 8 Co-authors: Cai G; Laslett LL; Winzenberg T; Jones G Tweet
2020	Cai G, Otahal P, Cicuttini F, Wu F, Munugoda IP, et al., 'The association of subchondral and systemic bone mineral density with osteoarthritis-related joint replacements in older adults', Osteoarthritis and Cartilage, 28, (4) pp. 438-445. ISSN 1063-4584 (2020) [Refereed Article] DOI: 10.1016/j.joca.2020.02.832 [eCite] [Details] Citations: Scopus - 2Web of Science - 3 Co-authors: Cai G; Otahal P; Wu F; Munugoda IP; Jones G Tweet
2020	Crisford P, Aitken D, Winzenberg T, Venn A, Cleland V, 'What factors are associated with physical activity promotion in the podiatry setting? a cross-sectional study', Journal of Science and Medicine in Sport pp. 1-7. ISSN 1440-2440 (2020) [Refereed Article] DOI: 10.1016/j.jsams.2020.08.008 [eCite] [Details] Citations: Scopus - 2Web of Science - 1 Co-authors: Crisford P; Winzenberg T; Venn A; Cleland V Tweet
2020	Gandham A, Zengin A, Bonham MP, Winzenberg T, Balogun S, et al., 'Incidence and predictors of fractures in older adults with and without obesity defined by body mass index versus body fat percentage', Bone, 140 Article 115546. ISSN 8756-3282 (2020) [Refereed Article] DOI: 10.1016/j.bone.2020.115546 [eCite] [Details] Citations: Scopus - 12Web of Science - 12 Co-authors: Winzenberg T; Balogun S; Wu F; Jones G; Scott D Tweet
2020	Munugoda IP, Beavers DP, Wirth W, Aitken DA, Loeser RF, et al., 'The effect of weight loss on the progression of meniscal extrusion and size in knee osteoarthritis: a post-hoc analysis of the Intensive Diet and Exercise for Arthritis (IDEA) trial', Osteoarthritis and Cartilage, 28, (4) pp. 410-417. ISSN 1063-4584 (2020) [Refereed Article] DOI: 10.1016/j.joca.2020.01.006 [eCite] [Details] Citations: Scopus - 8Web of Science - 7 Co-authors: Munugoda IP Tweet
2020	Munugoda IP, Pan F, Wills K, Mattap SM, Cicuttini F, et al., 'Identifying subgroups of community-dwelling older adults and their prospective associations with long-term knee osteoarthritis outcomes', Clinical Rheumatology, 39, (5) pp. 1429-1437. ISSN 0770-3198 (2020) [Refereed Article] DOI: 10.1007/s10067-019-04920-8 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Munugoda IP; Pan F; Wills K; Mattap SM; Jones G; Callisaya ML Tweet
2020	Thompson MJW, Jones G, Balogun S, Aitken DA, 'Constitutive melanin density is associated with prevalent and short-term, but not long-term, incident fracture risk in older Caucasian adults', Osteoporosis International, 31, (8) pp. 1517-1524. ISSN 0937-941X (2020) [Refereed Article] DOI: 10.1007/s00198-020-05304-4 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Thompson MJW; Jones G; Balogun S Tweet
2020	Thompson MJW, Jones G, Balogun SA, Aitken DA, 'Skin photosensitivity is associated with 25-Hydroxyvitamin D and BMD but not fractures independent of melanin density in older caucasian adults', Calcified Tissue International pp. 1-10. ISSN 0171-967X (2020) [Refereed Article] DOI: 10.1007/s00223-020-00728-w [eCite] [Details] Co-authors: Thompson MJW; Jones G; Balogun SA Tweet
2020	Wang Z, Jones G, Winzenberg T, Cai G, Laslett LL, et al., 'Effectiveness of Curcuma longa extract for the treatment of symptoms and effusion-synovitis of knee osteoarthritis : a randomized trial', Annals of Internal Medicine, 173, (11) pp. 861-869. ISSN 0003-4819 (2020) [Refereed Article] DOI: 10.7326/M20-0990 [eCite] [Details] Citations: Scopus - 47Web of Science - 42 Co-authors: Jones G; Winzenberg T; Cai G; Laslett LL; Singh A; Ding C; Antony B Tweet
2020	Zhao T, Ahmad H, Winzenberg T, Aitken D, de Graaff B, et al., 'Cross-sectional and temporal differences in health-related quality of life of people with and without osteoarthritis: a 10-year prospective study', Rheumatology pp. 1-8. ISSN 1462-0324 (2020) [Refereed Article] DOI: 10.1093/rheumatology/keaa787 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Zhao T; Ahmad H; Winzenberg T; de Graaff B; Jones G; Palmer AJ Tweet
2020	Zhao T, Ahmad H, de Graaff B, Xia Q, Winzenberg T, et al., 'A systematic review of the evolution of health-economic evaluation models of osteoarthritis', Arthritis Care & Research Article accepted manuscript. ISSN 2151-464X (2020) [Refereed Article] DOI: 10.1002/acr.24410 [eCite] [Details] Co-authors: Zhao T; Ahmad H; de Graaff B; Xia Q; Winzenberg T; Palmer AJ Tweet
2020	Zhao T, Winzenberg T, de Graaff B, Aitken D, Ahmad H, et al., 'A systematic review and meta-analysis of health state utility values for osteoarthritis-related conditions', Arthritis Care & Research ISSN 2151-464X (2020) [Refereed Article] DOI: 10.1002/acr.24478 [eCite] [Details] Citations: Scopus - 2Web of Science - 2 Co-authors: Zhao T; Winzenberg T; de Graaff B; Ahmad H; Palmer AJ Tweet
2019	Balogun S, Winzenberg T, Wills K, Scott D, Callisaya M, et al., 'Prospective associations of osteosarcopenia and osteodynapenia with incident fracture and mortality over 10 years in community-dwelling older adults', Archives of Gerontology and Geriatrics, 82 pp. 67-73. ISSN 0167-4943 (2019) [Refereed Article] DOI: 10.1016/j.archger.2019.01.015 [eCite] [Details] Citations: Scopus - 30Web of Science - 26 Co-authors: Balogun S; Winzenberg T; Wills K; Scott D; Callisaya M; Jones G Tweet
2019	Balogun S, Winzenberg T, Wills K, Scott DS, Jones G, et al., 'Prospective associations of low muscle mass and strength with health-related quality of life over 10-year in community-dwelling older adults', Experimental Gerontology, 118 pp. 65-71. ISSN 0531-5565 (2019) [Refereed Article] DOI: 10.1016/j.exger.2019.01.008 [eCite] [Details] Citations: Scopus - 11Web of Science - 12 Co-authors: Balogun S; Winzenberg T; Wills K; Scott DS; Jones G; Callisaya ML Tweet
2019	Cai G, Laslett LL, Aitken D, Cicuttini F, March L, et al., 'Zoledronic acid plus methylprednisolone versus zoledronic acid or placebo in symptomatic knee osteoarthritis: a randomized controlled trial', Therapeutic Advances in Musculoskeletal Disease, 11 pp. 1-12. ISSN 1759-720X (2019) [Refereed Article] DOI: 10.1177/1759720X19880054 [eCite] [Details] Citations: Scopus - 5Web of Science - 5 Co-authors: Cai G; Laslett LL; Winzenberg T; Jones G Tweet
2019	Cervo MM, Shivappa N, Hebert JR, Oddy WH, Winzenberg T, et al., 'Longitudinal associations between dietary inflammatory index and musculoskeletal health in community-dwelling older adults', Clinical Nutrition pp. 1-8. ISSN 0261-5614 (2019) [Refereed Article] DOI: 10.1016/j.clnu.2019.02.031 [eCite] [Details] Citations: Scopus - 31Web of Science - 29 Co-authors: Oddy WH; Winzenberg T; Balogun S; Wu F; Jones G; Scott D Tweet
2019	Han W, Aitken D, Zheng S, Wang B, Wluka AE, et al., 'Higher serum levels of resistin are associated with knee synovitis and structural abnormalities in patients with symptomatic knee osteoarthritis', Journal of the American Medical Directors Association, 20, (10) pp. 1242-1246. ISSN 1525-8610 (2019) [Refereed Article] DOI: 10.1016/j.jamda.2019.07.001 [eCite] [Details] Citations: Scopus - 6Web of Science - 7 Co-authors: Han W; Zheng S; Zhu Z; Blizzard L; Winzenberg T; Jones G; Ding C Tweet
2019	Mattap SM, Laslett LL, Squibb K, Wills K, Otahal P, et al., 'Hand examination, ultrasound and its association with hand pain and function in community-based older adults', Arthritis Care & Research pp. 1-28. ISSN 2151-464X (2019) [Refereed Article] DOI: 10.1002/acr.24128 [eCite] [Details] Citations: Scopus - 2 Co-authors: Mattap SM; Laslett LL; Squibb K; Wills K; Otahal P; Pan F; Winzenberg T; Jones G Tweet
2019	Pan F, Tian J, Aitken D, Cicuttini F, Jones G, 'Pain at multiple sites is associated with prevalent and incident fractures in older adults', Journal of Bone and Mineral Research, 34, (11) pp. 2012-2018. ISSN 0884-0431 (2019) [Refereed Article] DOI: 10.1002/jbmr.3817 [eCite] [Details] Citations: Scopus - 3Web of Science - 6 Co-authors: Pan F; Tian J; Jones G Tweet
2019	Zhai G, Pelletier J-P, Liu M, Aitken D, Randell E, et al., 'Activation of the phosphatidylcholine to lysophosphatidylcholine pathway is associated with osteoarthritis knee cartilage volume loss over time', Scientific Reports, 9, (1) Article 9648. ISSN 2045-2322 (2019) [Refereed Article] DOI: 10.1038/s41598-019-46185-w [eCite] [Details] Citations: Scopus - 25Web of Science - 25 Co-authors: Jones G Tweet
2019	Zhu Z, Aitken D, Cicuttini F, Jones G, Ding C, 'Ambulatory activity interacts with common risk factors for osteoarthritis to modify increases in MRI-detected osteophytes', Osteoarthritis and Cartilage, 27, (4) pp. 650-658. ISSN 1063-4584 (2019) [Refereed Article] DOI: 10.1016/j.joca.2018.12.023 [eCite] [Details] Citations: Scopus - 5Web of Science - 3 Co-authors: Zhu Z; Jones G; Ding C Tweet
2018	Aitken D, Laslett LL, Cai G, Hill C, March L, et al., 'A protocol for a multicentre, randomised, double-blind, placebo-controlled trial to compare the effect of annual infusions of zoledronic acid to placebo on knee structural change and knee pain over 24 months in knee osteoarthritis patients - ZAP2', BMC Musculoskeletal Disorders, 19, (1) Article 217. ISSN 1471-2474 (2018) [Contribution to Refereed Journal] DOI: 10.1186/s12891-018-2143-2 [eCite] [Details] Citations: Scopus - 19Web of Science - 19 Co-authors: Laslett LL; Cai G; Blizzard L; Jones G Tweet
2018	Aitken D, Laslett LL, Pan F, Haugen IK, Otahal P, et al., 'A randomised double-blind placebo-controlled crossover trial of HUMira (adalimumab) for erosive hand OsteoaRthritis - the HUMOR trial', Osteoarthritis and Cartilage, 26, (7) pp. 880-887. ISSN 1063-4584 (2018) [Refereed Article] DOI: 10.1016/j.joca.2018.02.899 [eCite] [Details] Citations: Scopus - 79Web of Science - 74 Co-authors: Laslett LL; Pan F; Otahal P; Jones G Tweet
2018	Balogun S, Aitken D, Winzenberg T, Wills K, Scott D, et al., 'Longitudinal associations of serum 25-hydroxyvitamin-D, physical activity, and knee pain and dysfunction with muscle loss in community-dwelling older adults', Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 73, (4) pp. 526-531. ISSN 1079-5006 (2018) [Refereed Article] DOI: 10.1093/gerona/glx157 [eCite] [Details] Citations: Scopus - 9Web of Science - 8 Co-authors: Balogun S; Winzenberg T; Wills K; Callisaya M; Jones G Tweet
2018	Balogun S, Winzenberg T, Wills K, Scott D, Jones G, et al., 'Longitudinal associations between serum 25-hydroxyvitamin D, physical activity, knee pain and dysfunction and physiological falls risk in community-dwelling older adults', Experimental Gerontology, 104 pp. 72-77. ISSN 0531-5565 (2018) [Refereed Article] DOI: 10.1016/j.exger.2018.01.026 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Balogun S; Winzenberg T; Wills K; Jones G; Callisaya M Tweet
2018	Cai G, Laslett LL, Aitken D, Halliday A, Pan F, et al., 'Effect of Zoledronic Acid and Denosumab in patients with low back pain and modic change: A proof-of-principle trial', Journal of Bone and Mineral Research, 33, (5) pp. 773-782. ISSN 0884-0431 (2018) [Refereed Article] DOI: 10.1002/jbmr.3376 [eCite] [Details] Citations: Scopus - 26Web of Science - 23 Co-authors: Cai G; Laslett LL; Pan F; Otahal P; Winzenberg TM; Jones G Tweet
2018	Crisford P, Winzenberg T, Venn A, Schultz M, Aitken D, et al., 'Factors associated with physical activity promotion by allied and other non-medical health professionals: a systematic review', Patient Education and Counseling, 101, (10) pp. 1775-1785. ISSN 0738-3991 (2018) [Refereed Article] DOI: 10.1016/j.pec.2018.05.011 [eCite] [Details] Citations: Scopus - 22Web of Science - 21 Co-authors: Crisford P; Winzenberg T; Venn A; Schultz M; Cleland V Tweet
2018	Han W, Aitken D, Zheng S, Wluka AE, Zhu Z, et al., 'Association between quantitatively measured infrapatellar fat pad high signal intensity alteration and MRI-assessed progression of knee osteoarthritis', Arthritis Care & Research pp. 1-26. ISSN 2151-464X (2018) [Refereed Article] DOI: 10.1002/acr.23713 [eCite] [Details] Citations: Scopus - 14Web of Science - 53 Co-authors: Han W; Zheng S; Zhu Z; Blizzard L; Winzenberg T; Jones G; Ding C Tweet
2018	Mattap SM, Aitken D, Wills K, Halliday A, Ding C, et al., 'Patellar tendon enthesis abnormalities and their association with knee pain and structural abnormalities in older adults', Osteoarthritis and Cartilage, 27, (3) pp. 449-458. ISSN 1063-4584 (2018) [Refereed Article] DOI: 10.1016/j.joca.2018.11.009 [eCite] [Details] Citations: Scopus - 5Web of Science - 4 Co-authors: Mattap SM; Wills K; Ding C; Han W; Munugoda I; Jones G; Laslett LL Tweet
2018	Mattap SM, Aitken D, Wills K, Laslett L, Ding C, et al., 'How do MRI-detected subchondral bone marrow lesions (BMLs) on two different MRI sequences correlate with clinically important outcomes?', Calcified Tissue International, 103, (2) pp. 131-143. ISSN 0171-967X (2018) [Refereed Article] DOI: 10.1007/s00223-018-0402-8 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Mattap SM; Wills K; Laslett L; Ding C; Jones G Tweet
2018	McMillan LB, Aitken D, Ebeling P, Jones G, Scott D, 'The relationship between objectively assessed physical activity and bone health in older adults differs by sex and is mediated by lean mass', Osteoporosis International, 29, (6) pp. 1379-1388. ISSN 0937-941X (2018) [Refereed Article] DOI: 10.1007/s00198-018-4446-4 [eCite] [Details] Citations: Scopus - 10Web of Science - 11 Co-authors: Jones G; Scott D Tweet
2018	Munugoda IP, Wills K, Cicuttini F, Graves SE, Lorimer M, et al., 'The association between ambulatory activity, body composition and hip or knee joint replacement due to osteoarthritis: a prospective cohort study', Osteoarthritis and Cartilage, 26, (5) pp. 671-679. ISSN 1063-4584 (2018) [Refereed Article] DOI: 10.1016/j.joca.2018.02.895 [eCite] [Details] Citations: Scopus - 17Web of Science - 15 Co-authors: Munugoda IP; Wills K; Jones G; Callisaya ML Tweet
2018	Pan F, Tian J, Aitken D, Cicuttini F, Jones G, 'Predictors of pain severity trajectory in older adults: a 10.7-year follow-up study', Osteoarthritis and Cartilage, 26, (12) pp. 1619-1626. ISSN 1063-4584 (2018) [Refereed Article] DOI: 10.1016/j.joca.2018.08.002 [eCite] [Details] Citations: Scopus - 26Web of Science - 26 Co-authors: Pan F; Tian J; Jones G Tweet
2018	Pan F, Tian J, Cicuttini F, Jones G, Aitken D, 'Differentiating knee pain phenotypes in older adults: a prospective cohort study', Rheumatology, 58, (2) pp. 274-283. ISSN 1462-0324 (2018) [Refereed Article] DOI: 10.1093/rheumatology/key299 [eCite] [Details] Citations: Scopus - 4Web of Science - 9 Co-authors: Pan F; Tian J; Jones G Tweet
2018	Thompson MJW, Jones G, Aitken DA, 'Constitutive melanin density is associated with higher 25-hydroxyvitamin D and potentially total body BMD in older Caucasian adults via increased sun tolerance and exposure', Osteoporosis International, 29, (8) pp. 1887-1895. ISSN 0937-941X (2018) [Refereed Article] DOI: 10.1007/s00198-018-4568-8 [eCite] [Details] Citations: Scopus - 5Web of Science - 4 Co-authors: Thompson MJW; Jones G Tweet
2018	Wu F, Xiao C, Aitken D, Jones G, Winzenberg T, 'The optimal dosage regimen of vitamin D supplementation for correcting deficiency in adolescents: a pilot randomized controlled trial', European Journal of Clinical Nutrition, 72, (4) pp. 534-540. ISSN 0954-3007 (2018) [Refereed Article] DOI: 10.1038/s41430-018-0098-x [eCite] [Details] Citations: Scopus - 8Web of Science - 6 Co-authors: Wu F; Xiao C; Jones G; Winzenberg T Tweet
2018	Zheng S, Tu L, Cicuttini F, Han W, Zhu Z, et al., 'Effect of vitamin D supplementation on depressive symptoms in patients with knee osteoarthritis', Journal of The American Medical Directors Association pp. 1-7. ISSN 1525-8610 (2018) [Refereed Article] DOI: 10.1016/j.jamda.2018.09.006 [eCite] [Details] Citations: Scopus - 16Web of Science - 15 Co-authors: Zheng S; Han W; Zhu Z; Antony B; Winzenberg T; Blizzard L; Jones G; Ding C Tweet
2018	Zheng S, Wang B, Han W, Zhu Z, Wang X, et al., 'Vitamin D supplementation and inflammatory and metabolic biomarkers in patients with knee osteoarthritis: post hoc analysis of a randomised controlled trial', British Journal of Nutrition, 120, (1) pp. 41-48. ISSN 0007-1145 (2018) [Refereed Article] DOI: 10.1017/S0007114518001174 [eCite] [Details] Citations: Scopus - 17Web of Science - 17 Co-authors: Zheng S; Han W; Zhu Z; Jin X; Antony B; Winzenberg T; Blizzard L; Jones G; Ding C Tweet
2017	Ahedi HG, Aspden RM, Blizzard LC, Saunders FR, Cicuttini FM, et al., 'Hip shape as a predictor of osteoarthritis progression in a prospective population cohort', Arthritis Care & Research, 69, (10) pp. 1566-1573. ISSN 2151-4658 (2017) [Refereed Article] DOI: 10.1002/acr.23166 [eCite] [Details] Citations: Scopus - 25Web of Science - 25 Co-authors: Ahedi HG; Blizzard LC; Jones G Tweet
2017	Balogun S, Winzenberg T, Wills K, Scott D, Jones G, et al., 'Prospective associations of low muscle mass and function with 10-year falls risk, incident fracture and mortality in community-dwelling older adults', Journal of Nutrition, Health and Aging, 21, (7) pp. 843-848. ISSN 1279-7707 (2017) [Refereed Article] DOI: 10.1007/s12603-016-0843-6 [eCite] [Details] Citations: Scopus - 71Web of Science - 70 Co-authors: Balogun S; Winzenberg T; Wills K; Jones G; Callisaya ML Tweet
2017	Pan F, Tian J, Aitken D, Cicuttini F, Winzenberg T, et al., 'The association of knee structural pathology with pain at the knee is modified by pain at other sites in those with knee osteoarthritis', Clinical Rheumatology, 36, (11) pp. 2549-2555. ISSN 0770-3198 (2017) [Refereed Article] DOI: 10.1007/s10067-017-3838-8 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Pan F; Tian J; Winzenberg T; Jones G Tweet
2017	Thompson MJW, Aitken DA, Otahal P, Cicolini J, Winzenberg TM, et al., 'The relationship between cumulative lifetime ultraviolet radiation exposure, bone mineral density, falls risk and fractures in older adults', Osteoporosis International, 28, (7) pp. 2061-2068. ISSN 0937-941X (2017) [Refereed Article] DOI: 10.1007/s00198-017-4001-8 [eCite] [Details] Citations: Scopus - 10Web of Science - 10 Co-authors: Thompson MJW; Otahal P; Winzenberg TM; Jones G Tweet
2017	Thompson MJW, Aitken DA, van der Mei IA, Otahal P, Cicolini J, et al., 'Predictors of Beagley-Gibson skin cast grade in older adults', Skin Research and Technology, 23, (2) pp. 235-242. ISSN 0909-752X (2017) [Refereed Article] DOI: 10.1111/srt.12328 [eCite] [Details] Citations: Scopus - 8Web of Science - 7 Co-authors: Thompson MJW; van der Mei IA; Otahal P; Winzenberg TM; Jones G Tweet
2017	Zheng S, Jin X, Cicuttini F, Wang X, Zhu Z, et al., 'Maintaining vitamin D sufficiency is associated with improved structural and symptomatic outcomes in knee osteoarthritis', American Journal of Medicine, 130, (10) pp. 1211-1218. ISSN 0002-9343 (2017) [Refereed Article] DOI: 10.1016/j.amjmed.2017.04.038 [eCite] [Details] Citations: Scopus - 25Web of Science - 21 Co-authors: Zheng S; Jin X; Zhu Z; Han W; Winzenberg T; Antony B; Blizzard L; Jones G; Ding C Tweet
2016	Ahedi HG, Aitken DA, Blizzard LC, Ding CH, Cicuttini FM, et al., 'Correlates of Hip Cartilage Defects: A Cross-sectional Study in Older Adults', Journal of Rheumatology, 43, (7) pp. 1406-1412. ISSN 0315-162X (2016) [Refereed Article] DOI: 10.3899/jrheum.151001 [eCite] [Details] Citations: Scopus - 13Web of Science - 13 Co-authors: Ahedi HG; Blizzard LC; Ding CH; Jones G Tweet
2016	Foong YC, Chherawala N, Aitken D, Scott D, Winzenberg T, et al., 'Accelerometer-determined physical activity, muscle mass, and leg strength in community-dwelling older adults', Journal of Cachexia, Sarcopenia and Muscle, 7, (3) pp. 275-283. ISSN 2190-6009 (2016) [Refereed Article] DOI: 10.1002/jcsm.12065 [eCite] [Details] Citations: Scopus - 70Web of Science - 68 Co-authors: Foong YC; Winzenberg T; Jones G Tweet
2016	Han W, Aitken D, Zhu Z, Halliday A, Wang X, et al., 'Signal intensity alteration in the infrapatellar fat pad at baseline for the prediction of knee symptoms and structure in older adults: a cohort study', ARD Online, 75 pp. 1783-1788. ISSN 1468-2060 (2016) [Refereed Article] DOI: 10.1136/annrheumdis-2015-208360 [eCite] [Details] Citations: Scopus - 47Web of Science - 54 Co-authors: Han W; Zhu Z; Antony B; Jones G; Ding C Tweet
2016	Han W, Aitken D, Zhu Z, Halliday A, Wang X, et al., 'Hypointense signals in the infrapatellar fat pad assessed by magnetic resonance imaging are associated with knee symptoms and structure in older adults: a cohort study', Arthritis Research & Therapy, 18, (1) Article 234. ISSN 1478-6362 (2016) [Refereed Article] DOI: 10.1186/s13075-016-1130-y [eCite] [Details] Citations: Scopus - 27Web of Science - 25 Co-authors: Han W; Zhu Z; Antony B; Jones G; Ding C Tweet
2016	Hill CL, March LM, Aitken D, Lester SE, Battersby R, et al., 'Fish oil in knee osteoarthritis: a randomised clinical trial of low dose versus high dose', Annals of the Rheumatic Diseases, 75, (1) pp. 23-29. ISSN 1468-2060 (2016) [Refereed Article] DOI: 10.1136/annrheumdis-2014-207169 [eCite] [Details] Citations: Scopus - 78Web of Science - 66 Co-authors: Hynes K; Jones G Tweet
2016	Johnson LG, Butson ML, Polman RC, Raj IS, Borkoles E, et al., 'Light physical activity is positively associated with cognitive performance in older community dwelling adults', Journal of Science and Medicine in Sport, 19, (11) pp. 877-882. ISSN 1440-2440 (2016) [Refereed Article] DOI: 10.1016/j.jsams.2016.02.002 [eCite] [Details] Citations: Scopus - 40Web of Science - 36 Co-authors: Jones G Tweet
2016	Khan HI, Aitken D, Ding C, Blizzard L, Pelletier JP, et al., 'Natural history and clinical significance of meniscal tears over 8 years in a midlife cohort', BMC Musculoskeletal Disorders, 17 Article 4. ISSN 1471-2474 (2016) [Refereed Article] DOI: 10.1186/s12891-015-0862-1 [eCite] [Details] Citations: Scopus - 15Web of Science - 13 Co-authors: Khan HI; Ding C; Blizzard L; Jones G Tweet
2016	Khan HI, Chou L, Aitken D, McBride A, Ding C, et al., 'Correlation between changes in global knee structures assessed on Magnetic Resonance Imaging and radiographic osteoarthritis changes over 10 years in a mid-life cohort', Arthritis Care & Research, 68, (7) pp. 958-964. ISSN 2151-4658 (2016) [Refereed Article] DOI: 10.1002/acr.22778 [eCite] [Details] Citations: Scopus - 5Web of Science - 4 Co-authors: Khan HI; McBride A; Ding C; Blizzard L; Jones G Tweet
2016	McBride A, Khan HI, Aitken D, Chou L, Ding C, et al., 'Does cartilage volume measurement or radiographic osteoarthritis at baseline independently predict ten-year cartilage volume loss?', BMC Musculoskeletal Disorders, 17 Article 54. ISSN 1471-2474 (2016) [Refereed Article] DOI: 10.1186/s12891-016-0900-7 [eCite] [Details] Citations: Scopus - 4Web of Science - 5 Co-authors: McBride A; Khan HI; Ding C; Blizzard L; Jones G Tweet
2016	Zhang W, Sun G, Aitken D, Likhodii S, Liu M, et al., 'Lysophosphatidylcholines to phosphatidylcholines ratio predicts advanced knee osteoarthritis', Rheumatology, 55, (9) pp. 1566-1574. ISSN 1462-0324 (2016) [Refereed Article] DOI: 10.1093/rheumatology/kew207 [eCite] [Details] Citations: Scopus - 56Web of Science - 55 Co-authors: Jones G; Zhai G Tweet
2015	Aitken D, Buchbinder R, Jones G, Winzenberg T, 'Interventions to improve adherence to exercise for chronic musculoskeletal pain in adults', Australian Family Physician, 44, (1-2) pp. 39-42. ISSN 0300-8495 (2015) [Refereed Article] [eCite] [Details] Citations: Web of Science - 21 Co-authors: Jones G; Winzenberg T Tweet
2015	Khan HI, Aitken D, Blizzard L, Ding C, Pelletier J-P, et al., 'History of knee injury and MRI-assessed knee structures in middle- and older-aged adults: a cross-sectional study', Clinical Rheumatology, 34 pp. 1463-1472. ISSN 1434-9949 (2015) [Refereed Article] DOI: 10.1007/s10067-014-2758-0 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 Co-authors: Khan HI; Blizzard L; Ding C; Jones G Tweet
2015	Khan HI, Aitken D, Chou L, McBride A, Ding C, et al., 'A family history of knee joint replacement increases the progression of knee radiographic osteoarthritis and medial tibial cartilage volume loss over 10 years', Osteoarthritis and Cartilage, 23, (2) pp. 203-209. ISSN 1063-4584 (2015) [Refereed Article] DOI: 10.1016/j.joca.2014.11.016 [eCite] [Details] Citations: Scopus - 17Web of Science - 16 Co-authors: Khan HI; McBride A; Ding C; Blizzard L; Jones G Tweet
2015	Khan HI, Aitken D, Chou L, McBride AP, Ding C, et al., 'Reply Letter to the Editor: Knee joint replacement and individual susceptibility for progression of knee osteoarthritis and tibial cartilage volume loss: not only genes run in the family', Osteoarthritis and Cartilage: Journal of The Osteoarthritis Research Society International, 23, (10) pp. 1819-20. ISSN 1063-4584 (2015) [Letter or Note in Journal] DOI: 10.1016/j.joca.2015.05.031 [eCite] [Details] Co-authors: Khan HI; McBride AP; Ding C; Blizzard CL; Jones Graeme Tweet
2015	Scott D, Ebeling PR, Sanders KM, Aitken D, Winzenberg T, et al., 'Vitamin D and physical activity status: Associations with five-year changes in body composition and muscle function in community-dwelling older adults', Journal of Clinical Endocrinology and Metabolism, 100, (2) pp. 670-678. ISSN 1945-7197 (2015) [Refereed Article] DOI: 10.1210/jc.2014-3519 [eCite] [Details] Citations: Scopus - 28Web of Science - 27 Co-authors: Winzenberg T; Jones G Tweet
2014	Ahedi H, Aitken D, Blizzard L, Cicuttini F, Jones G, 'A population-based study of the association between hip bone marrow lesions, high cartilage signal, and hip and knee pain', Clinical Rheumatology, 33, (3) pp. 369-376. ISSN 1434-9949 (2014) [Refereed Article] DOI: 10.1007/s10067-013-2394-0 [eCite] [Details] Citations: Scopus - 17Web of Science - 17 Co-authors: Ahedi H; Blizzard L; Jones G Tweet
2014	Ahedi HK, Aitken D, Scott D, Blizzard L, Cicuttini F, et al., 'The Association Between Hip Muscle Cross-Sectional Area, Muscle Strength, and Bone Mineral Density', Calcified Tissue International, 95, (1) pp. 64-72. ISSN 1432-0827 (2014) [Refereed Article] DOI: 10.1007/s00223-014-9863-6 [eCite] [Details] Citations: Scopus - 26Web of Science - 22 Co-authors: Ahedi HK; Blizzard L; Jones G Tweet
2014	Aitken D, Ding C, Pelletier JP, Martel-Pelletier J, Cicuttini F, et al., 'Responsiveness of Magnetic Resonance Imaging-derived Measures Over 2.7 Years', Journal of Rheumatology, 41, (10) pp. 2060-2067. ISSN 0315-162X (2014) [Refereed Article] DOI: 10.3899/jrheum.130953 [eCite] [Details] Citations: Scopus - 7Web of Science - 7 Co-authors: Ding C; Jones G Tweet
2014	Cao Y, Stannus OP, Aitken D, Cicuttini F, Antony B, et al., 'Cross-sectional and longitudinal associations between systemic, subchondral bone mineral density and knee cartilage thickness in older adults with or without radiographic osteoarthritis', Annals of the Rheumatic Diseases: The Euler Journal, 73, (11) pp. 2003-2009. ISSN 1468-2060 (2014) [Refereed Article] DOI: 10.1136/annrheumdis-2013-203691 [eCite] [Details] Citations: Scopus - 36Web of Science - 31 Co-authors: Cao Y; Stannus OP; Antony B; Jones G; Ding C Tweet
2014	Foong YC, Aitken D, Winzenberg T, Otahal P, Scott D, et al., 'The association between physical activity and reduced body fat lessens with age - Results from a cross-sectional study in community-dwelling older adults', Experimental Gerontology, 55 pp. 107-112. ISSN 0531-5565 (2014) [Refereed Article] DOI: 10.1016/j.exger.2014.04.006 [eCite] [Details] Citations: Scopus - 26Web of Science - 27 Co-authors: Foong YC; Winzenberg T; Otahal P; Jones G Tweet
2014	Foong YC, Khan HI, Blizzard L, Ding C, Cicuttini F, et al., 'The clinical significance, natural history and predictors of bone marrow lesion change over eight years', Arthritis Research & Therapy, 16, (4) Article R149. ISSN 1478-6362 (2014) [Refereed Article] DOI: 10.1186/ar4611 [eCite] [Details] Citations: Scopus - 20Web of Science - 20 Co-authors: Foong YC; Khan HI; Blizzard L; Ding C; Jones G Tweet
2014	Goldsmith GM, Aitken D, Cicuttini FM, Wluka AE, Winzenberg T, et al., 'Osteoarthritis bone marrow lesions at the knee and large artery characteristics', Osteoarthritis and Cartilage, 22, (1) pp. 91-94. ISSN 1063-4584 (2014) [Refereed Article] DOI: 10.1016/j.joca.2013.10.022 [eCite] [Details] Citations: Scopus - 11Web of Science - 11 Co-authors: Goldsmith GM; Winzenberg T; Ding CH; Jones G; Sharman JE Tweet
2014	Han W, Cai S, Liu Z, Jin X, Wang X, et al., 'Infrapatellar fat pad in the knee: Is local fat good or bad for knee osteoarthritis?', Arthritis Research & Therapy, 16, (4) Article R145. ISSN 1478-6362 (2014) [Refereed Article] DOI: 10.1186/ar4607 [eCite] [Details] Citations: Scopus - 70Web of Science - 64 Co-authors: Han W; Liu Z; Jin X; Antony B; Cao Y; Jones G; Ding C Tweet
2014	Scott D, Hayes A, Sanders KM, Aitken D, Ebeling PR, et al., 'Operational definitions of sarcopenia and their associations with 5-year changes in falls risk in community-dwelling middle-aged and older adults', Osteoporosis International, 25, (1) pp. 187-193. ISSN 1433-2965 (2014) [Refereed Article] DOI: 10.1007/s00198-013-2431-5 [eCite] [Details] Citations: Scopus - 100Web of Science - 95 Co-authors: Jones G Tweet
2014	Scott D, Sanders KM, Aitken D, Hayes A, Ebeling PR, et al., 'Sarcopenic obesity and dynapenic obesity: 5-year associations with falls risk in middle-aged and older adults', Obesity: a research journal, 22, (6) pp. 1568-1574. ISSN 1930-7381 (2014) [Refereed Article] DOI: 10.1002/oby.20734 [eCite] [Details] Citations: Scopus - 78Web of Science - 73 Co-authors: Jones G Tweet
2013	Ahedi H, Aitken D, Blizzard L, Cicuttini F, Jones G, 'The association between hip bone marrow lesions and bone mineral density: a cross-sectional and longitudinal population-based study', Osteoarthritis and Cartilage, 21, (10) pp. 1545-1549. ISSN 1063-4584 (2013) [Refereed Article] DOI: 10.1016/j.joca.2013.06.002 [eCite] [Details] Citations: Scopus - 6Web of Science - 8 Co-authors: Ahedi H; Blizzard L; Jones G Tweet
2013	Dore DA, Winzenberg TM, Ding C, Otahal P, Pelletier JP, et al., 'The association between objectively measured physical activity and knee structural change using MRI', Annals of the Rheumatic Diseases, 72, (7) pp. 1170-1175. ISSN 0003-4967 (2013) [Refereed Article] DOI: 10.1136/annrheumdis-2012-201691 [eCite] [Details] Citations: Scopus - 78Web of Science - 79 Co-authors: Winzenberg TM; Ding C; Otahal P; Jones G Tweet
2013	Khan HI, Aitken D, Zhai G, Ding C, Pelletier J-P, et al., 'Association between hip and knee cartilage measured using radiographs and magnetic resonance imaging: the Tasmanian Older Adult Cohort Study', Rheumatology, 52, (11) pp. 2009-2015. ISSN 0080-2727 (2013) [Refereed Article] DOI: 10.1093/rheumatology/ket243 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 Co-authors: Khan HI; Ding C; Blizzard L; Jones G Tweet
2012	Dore D, De Hoog J, Giles G, Ding C, Cicuttini F, et al., 'A longitudinal study of the association between dietary factors, serum lipids, and bone marrow lesions of the knee', Arthritis Research & Therapy, 14, (1) Article R13. ISSN 1478-6362 (2012) [Refereed Article] DOI: 10.1186/ar3689 [eCite] [Details] Citations: Scopus - 31Web of Science - 28 Co-authors: De Hoog J; Ding C; Jones G Tweet
2012	Laslett LL, Dore DA, Quinn SJ, Boon P, Ryan E, et al., 'Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial', Annals of the Rheumatic Diseases, 71, (8) pp. 1322-1328. ISSN 0003-4967 (2012) [Refereed Article] DOI: 10.1136/annrheumdis-2011-200970 [eCite] [Details] Citations: Scopus - 208Web of Science - 190 Co-authors: Laslett LL; Boon P; Winzenberg TM; Jones G Tweet
2012	Van der Mei IAF, Dore D, Winzenberg T, Blizzard L, Jones G, 'Vitamin D deficiency in Tasmania: A whole of life perspective', Internal Medicine Journal, 42, (10) pp. 1137-1144. ISSN 1444-0903 (2012) [Refereed Article] DOI: 10.1111/j.1445-5994.2012.02788.x [eCite] [Details] Citations: Scopus - 9Web of Science - 8 Co-authors: Van der Mei IAF; Winzenberg T; Blizzard L; Jones G Tweet
2011	Jones G, Schultz MG, Dore D, 'Physical Activity and Osteoarthritis of the Knee: Can MRI Scans Shed More Light on This Issue?', The Physician and Sportsmedicine: A Peer Reviewed Journal of Medical Aspects of Sports, Exercise and Fitness, 39, (3) pp. 55-61. ISSN 0091-3847 (2011) [Refereed Article] DOI: 10.3810/psm.2011.09.1921 [eCite] [Details] Citations: Scopus - 7Web of Science - 5 Co-authors: Jones G; Schultz MG Tweet
2010	Dore D, Ding C, Winzenberg T, Cicuttini F, Jones G, 'Reply to letter by Hayashi et al. commenting on choice of pulse sequences for MRI based semi-quantitative assessment of cartilage defects ', Arthritis & Rheumatism, 62, (12) pp. 3831-3832. ISSN 0004-3591 (2010) [Letter or Note in Journal] DOI: 10.1002/art.27730 [eCite] [Details] Citations: Scopus - 7Web of Science - 6 Co-authors: Ding C; Winzenberg T; Jones G Tweet
2010	Dore D, Martens A, Quinn S, Ding C, Winzenberg T, et al., 'Bone marrow lesions predict site-specific cartilage defect development and volume loss: a prospective study in older adults', Arthritis Research & Therapy, 12, (6) EJ ISSN 1478-6354 (2010) [Refereed Article] DOI: 10.1186/ar3209 [eCite] [Details] Citations: Scopus - 83Web of Science - 77 Co-authors: Martens A; Quinn S; Ding C; Winzenberg T; Jones G Tweet
2010	Dore D, Quinn S, Ding C, Winzenberg T, Cicuttini F, et al., 'Subchondral Bone and Cartilage Damage - A Prospective Study in Older Adults', Arthritis and Rheumatism, 62, (7) pp. 1967-1973. ISSN 0004-3591 (2010) [Refereed Article] DOI: 10.1002/art.27467 [eCite] [Details] Citations: Scopus - 54Web of Science - 49 Co-authors: Quinn S; Ding C; Winzenberg T; Jones G Tweet
2010	Dore D, Quinn S, Ding C, Winzenberg T, Zhai G, et al., 'Natural history and clinical significance of MRI-detected bone marrow lesions at the knee: a prospective study in community dwelling older adults', Arthritis Research & Therapy, 12, (6) EJ ISSN 1478-6354 (2010) [Refereed Article] DOI: 10.1186/ar3210 [eCite] [Details] Citations: Scopus - 113Web of Science - 101 Co-authors: Quinn S; Ding C; Winzenberg T; Jones G Tweet
2010	Stannus OP, Jones G, Quinn SJ, Cicuttini FM, Dore D, et al., 'The association between leptin, interleukin-6, and hip radiographic osteoarthritis in older people: a cross-sectional study', Arthritis Research & Therapy, 12, (3) EJ ISSN 1478-6354 (2010) [Refereed Article] DOI: 10.1186/ar3022 [eCite] [Details] Citations: Scopus - 61Web of Science - 56 Co-authors: Stannus OP; Jones G; Quinn SJ; Ding C Tweet
2009	Dore D, Quinn S, Ding C, Winzenberg T, Jones G, 'Correlates of Subchondral BMD: A Cross-Sectional Study', Journal of Bone and Mineral Research, 24, (12) pp. 2007-2015. ISSN 0884-0431 (2009) [Refereed Article] DOI: 10.1359/JBMR.090532 [eCite] [Details] Citations: Scopus - 43Web of Science - 41 Co-authors: Quinn S; Ding C; Winzenberg T; Jones G Tweet
2008	Dore D, Ding C, Jones G, 'A pilot study of the reproducibility and validity of measuring knee subchondral bone density in the tibia', Osteoarthritis and Cartilage, 16, (12) pp. 1539-1544. ISSN 1063-4584 (2008) [Refereed Article] DOI: 10.1016/j.joca.2008.04.012 [eCite] [Details] Citations: Scopus - 22Web of Science - 18 Co-authors: Ding C; Jones G Tweet

Review

(1 outputs)

Year	Citation	Altmetrics
2010	Van der Mei IAF, Dore D, 'Vitamin D supplementation in infants', Report for the Tasmanian Department of Health and Human Services (2010) [Substantial Review] [eCite] [Details] Co-authors: Van der Mei IAF

Year

Citation

Altmetrics

2010

Van der Mei IAF, Dore D, 'Vitamin D supplementation in infants', Report for the Tasmanian Department of Health and Human Services (2010) [Substantial Review]

[eCite] [Details]

Co-authors: Van der Mei IAF

Conference Publication

(7 outputs)

Year	Citation	Altmetrics
2020	Aitken D, Humphries D, Laslett L, Pitchford N, Khan HI, et al., 'Magnetic resonance imaging (MRI)-assessed knee abnormalities in Australian rules football players - AFL tas knee study', Osteoarthritis and Cartilage ISSN 1063-4584 (2020) [Conference Extract] [eCite] [Details] Co-authors: Laslett L; Pitchford N; Khan HI; Jones G; Winzenberg T
2018	Pan F, Tian J, Aitken D, Cicuttini F, Jones G, 'Pain at multiple sites is associated with prevalent and incident fractures in older adults: a 5.1-year follow-up study', Journal of Bone and Mineral Research, ASBMR Annual Meeting 2018, September - October, Montreal, Canada ISSN 0884-0431 (2018) [Conference Extract] [eCite] [Details] Co-authors: Pan F; Tian J; Jones G
2017	Foong Y, Aitken D, Humphries D, Laslett L, Pitchford N, et al., 'Knee function, pain and magnetic resonance imaging abnormalities in Australian Rules Football players: a cohort study', Internal Medicine Journal ISSN 1444-0903 (2017) [Conference Extract] DOI: 10.1111/imj.5_13463 [eCite] [Details] Co-authors: Foong Y; Laslett L; Pitchford N; Khan H; Jones G; Winzenberg T Tweet
2017	Pan F, Tian J, Aitken D, Cicuttini F, Ding C, et al., 'Characterizing and validating the phenotype of knee pain: a latent class analysis', Annals of the Rheumatic Diseases, pp. 471, June. ISSN 0003-4967 (2017) [Conference Extract] DOI: 10.1136/annrheumdis-2017-eular.3033 [eCite] [Details] Co-authors: Pan F; Tian J; Ding C; Jones G Tweet
2016	Pan F, Aitken D, Tian J, Cicuttini FM, Ding C, et al., 'Which factors associate with localized knee pain and generalized pain: A 10-year longitudinal study?', Arthritis & Rheumatology, pp. 1, Vol 68, (suppl 10). ISSN 2326-5191 (2016) [Conference Extract] [eCite] [Details] Co-authors: Pan F; Tian J; Ding C; Jones G
2009	Dore D, Ding C, Jones G, 'Natural history of areal bone marrow lesions', Osteoarthritis and Cartilage, Osteoarthritis Research Society International, September, Montreal, Canada, pp. S40-S40. (2009) [Conference Extract] [eCite] [Details] Co-authors: Ding C; Jones G
2009	Dore D, Ding C, Jones G, 'Which subchondral bone measure is the best predictor of cartilage damage?', Bone, pp. S144. (2009) [Conference Extract] [eCite] [Details] Co-authors: Ding C; Jones G

Entry

(1 outputs)

Year	Citation	Altmetrics
2020	Aitken D, Jones G, Winzenberg T, 'Clinical overview of osteoarthritis (OA) and the challenges faced for future management', Encyclopedia of Biomedical Gerontology, SIS Rattan (ed), 1, pp. 420-430 (2020) [Entry] DOI: 10.1016/B978-0-12-801238-3.11419-9 [eCite] [Details] Citations: Scopus - 3 Co-authors: Jones G; Winzenberg T Tweet

Year

Citation

Altmetrics

2020

Aitken D, Jones G, Winzenberg T, 'Clinical overview of osteoarthritis (OA) and the challenges faced for future management', Encyclopedia of Biomedical Gerontology, SIS Rattan (ed), 1, pp. 420-430 (2020) [Entry]

DOI: 10.1016/B978-0-12-801238-3.11419-9 [eCite] [Details]

Citations: Scopus - 3

Co-authors: Jones G; Winzenberg T

Grants & Funding

Funding Summary

Number of grants

Total funding

$8,916,698

Projects

Development of a co-design intervention to increase General Practitioners' referral rates to first-line treatment for knee and hip osteoarthritis (2023)$18,109

Description: The primary aim of this study is to work with GPs to co-design interventions to increase referral rates of people with osteoarthritis to GLA:D / exercise therapy. The co-designed intervention will be piloted and implemented in a future cluster-randomised controlled trial (RCT) to increase GP referral rates to exercise therapy. This study is a component of a large project that aims to provide high-value care for Tasmanians with osteoarthritis
Funding: ANZMUSC/ANZBACK CRE ($18,109)
Scheme: Grant-Seed
Administered By: University of Tasmania
Research Team: Balogun S; Aitken D; Barton C; Ezzat A; Lawler K; Winzenberg TM; Mulford J
Year: 2023

ACTIVE KNEECAPS! tArgeted effeCTIVE treatments for adolescent KNEECAP pain (2023)$2,043,046

Description: More than one-quarter of adolescents live with regular, debilitating kneecap pain each year. This leads to disability during daily activities, lower quality of life, and high rates of withdrawal from sport, physical activity and social interactions. Kneecap pain in adolescence is not a self-limiting disease. 75% of adolescents have persistent PFP for up to 20 years, setting the scene for a lifetime of knee pain and associated health implications, such as arthritis. Adolescents who present to primary care for their kneecap pain are met by clinicians who do not have the evidence to make informed treatment decisions. Best-practice exercise treatments for adults with kneecap pain are only half as effective for adolescents, and do not address their unique needs. Our vision is to address this knowledge gap by providing stakeholders with co-designed, evidence-based treatments that are acceptable, safe and effective for adolescents with kneecap pain. ACTIVE KNEECAPs will determine if (i) shoe inserts or (ii) targeted physiotherapy are more effective and cost-effective over 1 year than (iii) providing simple advice. Key outcomes are pain severity, function in daily and sporting activities, quality of life, and physical activity. Leveraging our multidisciplinary team's existing knowledge translation platforms and strong relationships with key stakeholders, we will develop tools to facilitate uptake of evidence-based treatments in primary care. Through the combination of a high-quality randomised controlled trial, embedded knowledge translation activities, and an expert multidisciplinary team of investigators and clinical partners, our project will result in tangible beneficial changes to health practice in primary care, better health outcomes for adolescents with kneecap pain, and increased health efficiency.
Funding: Medical Research Future Fund ($2,043,046)
Scheme: Grant-Chronic Musculoskeletal Conditions Children
Administered By: University of Queensland
Research Team: Collins N; Aitken D
Year: 2023

Walk with Ease Australia (2023)$591,280

Description: Osteoarthritis (OA) is a serious and debilitating condition that affects over 3 million Australians and yet there is still no cure. In 2018, the National Osteoarthritis Strategy identified seven priority areas throughout a person's journey with OA, from prevention, early treatment to end-stage management and joint replacement. A key goal of the Strategy was to improve the uptake of physical activity and exercise by Australians diagnosed with, or at risk of developing OA. Currently, 90% of people with OA do not meet physical activity guidelines. This grant proposal will test an innovative public health approach to address risk factors associated with the prevalence and persistence of OA in Australia and implement these approaches to improve the quality and cost-effectiveness of preventative healthcare interventions. We propose to develop, evaluate, and implement a sustainable, community-driven walking program for people with OA. The Walk with Ease program is a 6-week walking program developed by the Arthritis Foundation in the USA that is proven to reduce pain and improve function in people with moderate to severe levels of pain. This program will be adapted to the Australian setting by partnering with state-based arthritis consumer groups who will co-design the delivery of the program that will have a focus on engagement, adherence, and long-term sustainability.
Funding: Medical Research Future Fund ($591,280)
Scheme: Grant - Preventative and Public Health Research
Administered By: University of Sydney
Research Team: Hunter D; Aitken D
Year: 2023

Evidence scan update on hip fracture and knee osteoarthritis (2022)$86,000

Description: Limited literature search to update the existing literature review for the Hip Fracture Care and Osteoarthritis of the Knee Clinical Care Standards (that we conducted in 2020).
Funding: KP Health ($86,000)
Scheme: Consultancy
Administered By: University of Tasmania
Research Team: Winzenberg TM; Aitken D; Makin JK; Scheepers EJ
Year: 2022

Providing high-value care for osteoarthritis patients at the Royal Hobart Hospital (RHH) (2022)$24,943

Description: GLA:D is an international evidence-based education and exercise program for people with knee and hip osteoarthritis. This project will evaluate the implementation of GLA:D through the RHH physiotherapy community outpatient clinics for patients on a joint replacement surgery pathway. It will benefit patients and potentially reduce pressure on elective surgery waiting lists.
Funding: Royal Hobart Hospital Research Foundation ($24,943)
Scheme: Grant-Project
Administered By: University of Tasmania
Research Team: Aitken D; Lawler K; Harvie P; O'Brien L; Barton C; Hyland P; de Graaff B; Van Dam PJ; Peterson GM; Collins N; Jones G
Year: 2022

Donation: TCHI - IMPACT-TAS: Improving access to high-value care for osteoarthritis in Tasmania (2021)$78,465

Description: Donation for "Improving access to high-value care for osteoarthritis: IMPACT-TAS"
Funding: Donation via University of Tasmania Foundation ($78,465)
Scheme: Donation - Individual
Administered By: University of Tasmania
Research Team: Winzenberg TM; Aitken D
Year: 2021

Evidence scan on hip fracture and knee osteoarthritis (2020)$35,000

Description: Conduct limited scope evidence-based literature reviews to inform the Australia Commission on Safety and Quality in Health Care's review of the Hip Fracture Care and Osteoarthritis of the Knee Clinical Care Standards.
Funding: KP Health ($35,000)
Scheme: Consultancy
Administered By: University of Tasmania
Research Team: Winzenberg TM; Makin JK; Aitken D
Year: 2020

Providing high-value care for osteoarthritis patients at the Royal Hobart Hospital (RHH) (2020)$12,940

Description: This prospective, observational study will recruit patients undergoing primary elective hip or knee joint replacement at study sites in Tasmania. Participants will complete patient reported outcome measure (PROMs) surveys and have accelerometry data collected preoperatively and at 6 weeks, 12 weeks, 6 months and 12 months post-operatively. The trajectory of their recovery is measured both by their subjective PROMs responses and objective movement data captured by accelerometry to provide insights into expected performance changes and evaluate PROMs characteristics.The project aims to quantify physical performance changes that occur in patients following hip or knee arthroplasty and compare the relationship between this objective data and subjective PROMs.
Funding: The MPST Foundation Ltd ($12,940)
Scheme: Grant
Administered By: University of Tasmania
Research Team: Aitken D; Laslett LL; Harvie P; Haward CP
Year: 2020

Achieving the balance between the risks and benefits of cumulative lifetime sun exposure (2019 - 2023)$114,033

Funding: National Health & Medical Research Council ($114,033)
Scheme: Scholarship-Postgraduate
Administered By: University of Tasmania
Research Team: Aitken D; Thompson M
Period: 2019 - 2023
Grant Reference: GNT1168209

Stem Cells as a symptom- and strUcture-modifying Treatment for knee OsteoaRthritis- the SCUlpTOR trial. (2019 - 2024)$1,982,802

Description: This project aims to assess, using a parallel-group randomised controlled design, the effect of allogeneic mesenchymal stem cells compared with placebo (saline) on knee OA-related clinical outcomes and knee joint structure over 24 months.
Funding: National Health & Medical Research Council ($1,982,802)
Scheme: Grant-Project
Administered By: University of Sydney
Research Team: Hunter D; Ding C; Lohmander S; O'Connell R; Wang X; Aitken D
Period: 2019 - 2024
Grant Reference: 1162874

DICKENS - A randomised controlled trial of DIaCerein to treat KneE osteoarthritis with effusioN-Synovitis (2018 - 2022)$1,859,767

Description: Knee osteoarthritis (OA) is common, but the current treatments are poor. Almost 60% of people with knee OA have joint inflammation. Patients with inflammation are more likely to experience joint pain and rapid joint destruction. We propose that treating patients with inflammatory knee OA with the anti-inflammatory drug, diacerein, will reduce pain and joint damage.
Funding: National Health & Medical Research Council ($1,309,503)
Collaborators: Monash University ($150,970); University of Adelaide ($231,143); University of Western Australia ($168,151)
Scheme: Grant-Project
Administered By: University of Tasmania
Research Team: Aitken D; Jones G; Cicuttini FM; Winzenberg TM; Keen H
Period: 2018 - 2022
Grant Reference: 1147370

Improving musculoskeletal pain by matching the right treatment with the right patient (2018 - 2021)$431,000

Funding: Medical Research Future Fund ($431,000)
Scheme: Fellowship-Career Development
Administered By: University of Tasmania
Research Team: Aitken D
Period: 2018 - 2021

A randomised controlled trial evaluating community walking for knee osteoarthritis (2018)$30,000

Description: This project will implement a community walking group for patients with knee osteoarthritis. This pilot study aims to evaluate the feasibility of recruitment, retention, randomisation and the implementation of a RCT aimed to examine the effect walking has on knee structure (assessed using advanced magnetic resonance imaging (MRI) technology). We will recruit 48 participants with knee osteoarthritis who will be randomised to either a 6-month community walking group or a usual care (control) group. Participants in the walking group will train 3 days per week for 1 hour each day. Walking will be performed at a moderate intensity (50-70% of each participant's heart rate reserve). This frequency/intensity is recommended for Australian adults (Australian National Physical Activity Guidelines) and for adults with knee osteoarthritis (Arthritis Australia). The structure of our program is based on a group walking protocol which showed improvement in pain in knee osteoarthritis patients. The walking program will be supervised by accredited physiotherapists with experience in prescribing exercise for knee osteoarthritis patients. Each group walking session will consist of:*10 min warm up consisting of slow walking and calisthenics: arm circles, trunk rotation, shoulder and chest stretches, and side stretch.*40 min group walking phase where participants are encouraged to walk at 50-70% of their heart rate reserve as determined from an exercise treadmill test at the start of the study. *10 min cool down consisting of slow walking and flexibility exercises. Participants randomised to usual care will receive usual standard care from their medical practitioner, as well as generic information about knee osteoarthritis. This will the control group, and this is required in order to examine the true effect walking has on knee health.
Funding: Arthritis Australia ($30,000)
Scheme: Grant-Project
Administered By: University of Tasmania
Research Team: Aitken D; Jones G; Callisaya M; Balogun S
Year: 2018

Improving musculoskeletal pain by matching the right treatment with the right patient - Medical Research Future Fund (MRFF) Next Generation Clinical Researchers Program - Career Development Fellowship (2018)$82,000

Description: During the course of my CDF Fellowship I am leading five innovative research projects that aim to provide clinically translatable evidence offering new effective treatments that improve outcomes for patients with musculoskeletal diseases. Four out of the five research projects are funded either by NHMRC or industry. I am applying for the ASBMR Rising Star award to fund part of the fifth project in my research program: Do osteoporosis therapies work for back pain? We will recruit 125 patients with chronic low back pain patients. Men and women will be recruited if they are >34 years of age, have at least moderate back pain (≥40/100 on 100mm VAS) for at least 3 months, and have type 1, type 2 or mixed type Modic changes on MRI (same inclusion criteria in MODIC1). Exclusion criteria include: Neuropathic pain component is unclear/definite (painDETECT questionnaire13 score ≥12, based on MODIC1 findings); Diagnosis of a centrally mediated pain phenotype (e.g. fibromyalgia); Prior use of denosumab or bisphosphonates; Serum 25-hydroxyvitamin D concentrations < 40 nmol/L; Pregnancy or breastfeeding; Prior cancer diagnosis; Poor dental fitness; Use of high doses of opiate pain medication (equivalent to oxycontin ≥80mg/day); Leg pain is of greater severity than back pain; Back surgery within the last 5 years.Eligible participants will receive one subcutaneous injection of denosumab (60mg in 1ml saline) or 1ml saline every 6 months for 24 months (0, 6, 12, 18 months).
Funding: American Society for Bone and Mineral Research ($82,000)
Scheme: Grant-Rising Star Award
Administered By: University of Tasmania
Research Team: Aitken D
Year: 2018

Unlocking the potential of a novel setting to promote physical activity (PA) among patients with Knee Osteoarthritis (KOA) - parkrun (2018 - 2019)$31,313

Description: Participating in PA reduces pain and improves function in people with KOA. Despite this, people with KOA are alarmingly inactive. It is, therefore, of high priority to identify effective, low-cost and sustainable PA promotion strategies for KOA. parkrun is an international movement of weekly 5 km walk/run events held in public spaces. Parkrun has a broad appeal to various population groups including non-athletes, however no previous reports had evaluated parkrun as a promising PA promotion setting for KOA. Our study will determine the feasibility, acceptability and safety of parkrun as a novel strategy to promote PA for people with KOA.
Funding: Medibank Better Health Foundation ($31,313)
Scheme: Grant - Project Grant Funding
Administered By: University of Tasmania
Research Team: Aitken D; Lahham A; Jose KA; Cleland V; Jones G; Winzenberg TM; Grunseit A
Period: 2018 - 2019

Assessing the Australian osteoarthritis landscape - GPs' surgeons' and patients attitudes towards and understandings of osteoarthritis (2018)$24,824

Description: Osteoarthritis is a leading cause of pain and disability among older people and there is currently no cure. In recent years, there has been increasing concern about the discrepancies between care provided by health professionals and recommendations in osteoarthritis clinical practice guideline. For instance, in Australia, referral to a surgeon is five times more common than referral to allied health professionals that could help with conservative management. Furthermore, patients are ambivalent towards conservative management such as exercise, thinking it will be ineffective and may even cause harm to their already worn joints. The disconnect between practice guideline and care for patients with osteoarthritis limits optimal care. Therefore, this study aims to explore the attitudes towards and understanding of osteoarthritis held by Australian GPs, surgeons and patients with knee osteoarthritis. The overarching goal is to gather information needed to develop Australian-specific education and behaviour change programs for GPs, surgeons and osteoarthritis patients
Funding: University of Tasmania ($24,824)
Scheme: Grant- Research Enhancement Program
Administered By: University of Tasmania
Research Team: Balogun S; Aitken D; Winzenberg TM; Hansen EC; Newsham-West H; Laslett LL
Year: 2018

Improving outcomes in patients with knee osteoarthritis: identifying pain phenotypes with relationships to long-term health outcomes (2018)$9,669

Description: Knee osteoarthritis is a highly heterogeneous condition characterised by a complex and multifactorial nature. The pain experience in knee osteoarthritis is similarly individualized and complex; some patients may present with pain that appears attributable to classic signs of joint damage, while others may present with pain due to psychological distress or central mechanisms. However, whether these variables (or interactions between variables) are representative of different pain phenotypes in knee osteoarthritis and whether patients with distinct pain phenotypes have different risk for long-term health outcomes are unknown. This project aims to identify the pain phenotypes in OA patients and compare the risk of long-term health outcomes between different pain phenotypes. This study will help clinicians better prioritize and target interventions to individual patients and will lead to better outcomes and fewer treatment complications currently associates with pharmaceutical and surgical interventions that are widely used to treat knee osteoarthritis.
Funding: University of Tasmania ($9,669)
Scheme: Grant- Research Enhancement Program
Administered By: University of Tasmania
Research Team: Pan F; Jones G; Winzenberg TM; Tian J; Aitken D
Year: 2018

The effect of krill oil on cartilage composition (2016)$30,000

Description: Aims: to compare efficacy of krill oil vs identical placebo on cartilage composition (T2 mapping values) in 260patients with clinical knee OA, significant knee pain and effusion on imaging, using a randomised, placebo-controlled double-blind design over six months in an NHMRC-funded clinical trial.
Funding: Menzies Institute for Medical Research ($30,000)
Scheme: Grant - Development Grant
Administered By: University of Tasmania
Research Team: Laslett LL; Eathakkattu Antony BS; Aitken D
Year: 2016

Testing new treatments for back pain: a randomised open label pilot study (2014)$88,721

Description: This project will conduct a randomised open label pilot study on two potential treatments for back pain targeting Modic changes (zoledronic acid or denosumab).
Funding: Tasmanian Community Fund ($88,721)
Scheme: Grant
Administered By: University of Tasmania
Research Team: Laslett LL; Aitken D; Jones G
Year: 2014

Osteoarthritis research (2013)$1,000

Funding: The Royal Society of Tasmania ($1,000)
Scheme: Doctoral (PhD) Award for 2013
Administered By: Menzies Research Institute Tasmania
Research Team: Aitken Dawn
Year: 2013

Using magnetic resonance imaging (MRI) to improve understanding of knee osteoarthritis and develop effective therapeutic treatments (2013 - 2016)$299,564

Funding: National Health & Medical Research Council ($299,564)
Scheme: Fellowship-Early Career
Administered By: University of Tasmania
Research Team: Aitken D
Period: 2013 - 2016
Grant Reference: 1052708

A randomised trial of zoledronic acid for osteoarthritis of the knee (2013 - 2015)$954,596

Description: Osteoarthritis (OA) is the most common form of arthritis and is increasing markedly due to an ageing population. Despite its large disease burden, there are currently no approved disease-modifying drugs available which modify structural progression of OA. The aim of this study is to compare zoledronic acid treatment to placebo on knee structural change and knee pain over two years. It is hypothesised that zoledronic acid will reduce cartilage loss, knee pain, and bone marrow lesion size.
Funding: National Health & Medical Research Council ($954,596)
Scheme: Grant-Project
Administered By: University of Tasmania
Research Team: Jones G; Cicuttini FM; March L; Hill C; Aitken D
Period: 2013 - 2015
Grant Reference: 1045415

2012: 6th International Workshop on Osteoarthritis Imaging combined with the OARSI OA Biomarkers Workshop II - Imaging Biomarker Validation and Qualification, USA (2012)$1,500

Funding: University of Tasmania ($1,500)
Scheme: Grant-Conference Support Scheme
Administered By: University of Tasmania
Research Team: Aitken D
Year: 2012

Vitamin D for correcting deficiency in adolescents: a general practice-based RCT (2012 - 2014)$30,000

Funding: Royal Australian College of General Practitioners/Osteoporosis Australia ($30,000)
Scheme: Grant-Bone Health
Administered By: University of Tasmania
Research Team: Winzenberg TM; Aitken D; Jones G
Period: 2012 - 2014

Structural predictors of knee replacement surgery (2011)$50,000

Funding: Arthritis Australia ($50,000)
Scheme: Fellowship-Research
Administered By: University of Tasmania
Research Team: Aitken D
Year: 2011

Scientific Exchange to University of California, San Francisco to work on Osteoarthritis Initiative Study (OAI) (2010)$6,126

Funding: Osteoarthritis Research Society International ($6,126)
Scheme: Scholarship-Exchange
Administered By: University of Tasmania
Research Team: Aitken D
Year: 2010

Research Supervision

Current

Completed

Current

Degree	Title	Commenced
PhD	Physical Activity and Osteoarthritis	2021
PhD	Comparative Effectiveness of Treatments for Osteoarthritis: Efficacy and safety of yoga-based exercise program and krill oil supplemetation	2023
PhD	Optimising Osteoarthritis Management	2023
PhD	Obesity and Musculoskeletal Pain	2023
PhD	Evaluating the Clinical Utility of Osteoarthritis Pain Phenotypes	2023

Completed

Degree	Title	Completed
PhD	The Relationship and Interactions between Sun Exposure, Skin Phenotype and Musculoskeletal Health in Older Adults Candidate: Michael John William Thompson	2023
PhD	Understanding the Management of Osteoarthritis in Tasmania and a Novel Approach to Change Candidate: Laura Pearl Sutton	2023
PhD	Investigating the Evolution of Model-based Health Economic Evaluations and Changes in Health-related Quality of Life in Osteoarthritis Candidate: Ting Zhao	2021
PhD	Utilising Advanced Imaging to Understand Joint Pain and Function Limitations in Older Adults Candidate: Siti Maisarah Binti Mattap	2021
PhD	Clinical Trials of Bone-targeted Therapy for New Indications Candidate: Guoqi Cai	2020
PhD	Determinants and Management of the Progression of Osteoarthritis in Older Adults Candidate: Ishanka Praneeth Munugoda	2020
PhD	Knee Osteoarthritis, Its Comorbidity and the Role of Vitamin D Candidate: Shuang Zheng	2019
PhD	How and Why do Podiatrists Promote Physical Activity? Candidate: Paul Raymond Crisford	2019
PhD	Infrapatellar Fat Pad and Knee Osteoarthritis Candidate: Weiyu Han	2019
PhD	Long-Term Risk Factors for, and the Impact of Age-related Muscle Loss on the Musculoskeletal Health of Older Adults Candidate: Saliu Adejumobi Balogun	2018
PhD	Determinants of Structural Changes in the Knee Joint in a Middle-Aged Cohort with a Low Prevalence of Osteoarthritis Candidate: Hussain Ijaz Khan	2017
PhD	Assessment of Hip Structure and Musculature using MRI and DXA Images from Tasoac Cohort Candidate: Harbeer Kaur Ahedi	2016