Profiles

Laura Laslett

Dr Laura Laslett

Laura Laslett

NHMRC Early Career Fellow
Menzies Institute for Medical Research

Room 356-02 , Medical Science 2

+61 3 6226 7736 (phone)

+61 3 6226 7704 (fax)

Laura.Laslett@utas.edu.au

Dr Laura Laslett is a musculoskeletal epidemiologist and NHMRC Early Career Fellow at the Menzies Institute for Medical Research. Her research focuses on osteoarthritic pain.

Biography

Dr Laslett moved to Hobart in 2009 to complete a PhD on determinants, correlates, modifiers of musculoskeletal pain at the Menzies Institute for Medical Research, University of Tasmania. She commenced postdoctoral work in 2013 as an Arthritis Australia Heald Fellow, and then as an NHMRC Early Career Fellow in 2014.

Prior to moving to Hobart, Laura worked as a research officer at the Discipline of Medicine at The University of Adelaide (Modbury Hospital) for 6 years, and as an epidemiologist for SA Health for 2 years. She also completed a 3 month placement at the Division of Rheumatic and Musculoskeletal Disease at the University of Leeds (Leeds UK) in 2012, funded by an Osteoarthritis Research Society International Young Investigator Scholarship. She has worked with several research groups (Adelaide, Hobart and Leeds (UK)) and has expertise in the conduct and analysis of intervention studies, including 4 clinical trials and an educational intervention for osteoporosis.

Career summary

Qualifications

PhD, University of Tasmania, Australia, 2013. Determinants, correlates and modifiers of musculoskeletal pain
MMedScience, The University of Adelaide, Australia, 2003. Screening for low bone mineral density in patients with respiratory disease
Grad Dip Public Health, The University of Adelaide, Australia, 2014
BSc (Hons), The University of Adelaide, Australia, 1999. Epidemiological Risk Factors for Unexplained Fetal Death
BSc, The University of Adelaide, Australia, 1998

Memberships

Professional practice

Osteoarthritis Research Society International
Public Health Association of Australia
Australasian Epidemiology Association
Australia and New Zealand Bone and Mineral Society

Administrative expertise

Management of clinical trials. Writing of study protocols and research-related clinical trial administration eg NEAF, CTN forms
Use of the Teleform system to assist in data collection for participant-based trials

Teaching

Principles of epidemiology, Bias and confounding, Musculoskeletal pain, Musculoskeletal health

Teaching expertise

I teach epidemiological principles, and epidemiological methods, including bias and confounding at both undergraduate and graduate level.

Teaching responsibility

I contribute to teaching in CEA200 (Population Health) and CEA501 (Introduction to Epidemiology) as well as epidemiology short courses.

Research Appointments

Dr Laslett is a Branch Officer for the Tasmanian Branch of the Public Health Association of Australia

View more on Dr Laura Laslett in WARP

Expertise

Knee pain
Back pain
Osteoporosis
Osteoarthritis
Musculokeletal pain, arthritic pain
Musculoskeletal health
Clinical trials for musculoskeletal pain

Research Themes

Despite the large impact of osteoarthritis on the community there are currently no treatments that are approved to change the disease course, and current treatments focus on reducing pain and improving function – the major symptoms of osteoarthritis. However, there is a significant gap between the level of pain relief patients want, and what they actually get from treatments available today.

Dr Laslett's research has focussed on targeting OA treatments to people with OA with different sources of pain. One study from Dr Laslett's PhD demonstrated the first proof of principle for using an osteoporosis drug and demonstrating that it had effects in a key structural feature of OA (bone marrow lesions), and reduced knee pain in people with knee OA (ZAP1 trial). A second study from her PhD demonstrated that a natural therapy was effective in reducing pain in people with knee OA.

She is currently running the Modic trial, in people with a similar structural feature to bone marrow lesions (Modic changes), and back pain. This study is testing two different osteoporosis treatments to assess whether they are effective in reducing back pain and Modic changes. She is currently involved with several other clinical trials for treating pain in the knees and hands.

Dr Laslett's research aligns to the University's research theme of Better Health. Her research interests include understanding sources of pain in osteoarthritis, and testing interventions that have the potential to treat musculoskeletal pain, and to change disease course of osteoarthritis and other musculoskeletal conditions.

Dr Laslett is also involved in the analysis of observational data to answer important clinical questions on pain and how it might be treated. She is working with Sarah Mattap (Honours student) to determine whether pathological changes at the tibial enthesis is associated with pain and other structural factors normally associated with knee pain. She collaborates with colleagues at the University of Leeds on analysis of data from a large US-based cohort to assess links between lower limb and upper limb pain, and collaborates with researchers at La Trobe University on non-structural factors associated with existing and new foot pain.

Collaboration

Laura currently collaborates with researchers at the University of Leeds and imorphics (Manchester). This work involves assessing predictors of newly painful joints, and assessing the effect of treatment with bone active medication changes the shape of knee joints.

She also collaborates with researchers at Monash University, Sydney University, the Queen Elizabeth Hospital, and the University of Western Australia on clinical trials in knee pain; and with researchers at La Trobe University on factors associated with foot pain.

Awards

Menzies Research Institute Tasmania Postgraduate student award (AUD$2000), 2012
OARSI Young Investigator Scholarship to go to Leeds, UK for 3 months (US$6500), 2012
Poster prize: Best poster and best poster defence at the Sharing Excellence in Research Conference (UTAS Graduate Research), Hobart (AUD$1000), 2011
Young Investigator Award, OARSI imaging conference (Salzburg, Austria) (€700), 2011
Abstract Prize: Best abstract, Osteoarthritis section, European League against Rheumatism (EULAR) conference, London (€1000), 2011
Poster Prize: Best Clinical Poster at the Australian Rheumatology Association conference (Melbourne) (AUD$500), 2010
Poster Prize: Best poster in the Rheumatology Health Professionals section at the Australian Rheumatology Association conference (Adelaide) (AUD$500), 2008

Current projects

Modic trial
HUMOR trial
ZAP2 trial
Osteoarthritis of the Knee Statin (OAKS) Study
Knee pain predicts new shoulder pain and associations are mediated by weakness. Data analysis from the Osteoarthritis Initiative
Do ligament and enthesis abnormalities predict pain? An MRI investigation of the role of enthesis abnormalities in patellofemoral pain, using data from the TASOAC study.Non-structural correlates of foot pain: data analysis from the TASOAC study

Fields of Research

Rheumatology and arthritis (320223)
Clinical sciences (320299)
Epidemiology (420299)
Neurology and neuromuscular diseases (320905)
Health economics (380108)
Nutritional science (321004)
Orthopaedics (320216)
Geriatrics and gerontology (320210)
Zoology (310999)
Physiotherapy (420106)
Medical biotechnology diagnostics (incl. biosensors) (320602)
Radiology and organ imaging (320222)
Endocrinology (320208)
Traditional, complementary and integrative medicine (420899)
Digital health (420302)
Aged health care (420301)
Health and community services (420305)
Oral medicine and pathology (320307)
Education assessment and evaluation (390402)
Peripheral nervous system (320906)
Biomedical instrumentation (400305)
Health psychology (520304)
Health management (420309)
Cellular immunology (320404)
Sports medicine (320225)
Primary health care (420319)
Rehabilitation (420109)
Sports science and exercise (420799)

Research Objectives

Clinical health (200199)
Treatment of human diseases and conditions (200105)
Evaluation of health outcomes (200202)
Diagnosis of human diseases and conditions (200101)
Prevention of human diseases and conditions (200104)
Health related to ageing (200502)
Disability and functional capacity (200403)
Health status (incl. wellbeing) (200407)
Allied health therapies (excl. mental health services) (200301)
Other health (209999)
Efficacy of medications (200102)
Primary care (200310)
Women's and maternal health (200509)
Policies and development (160205)
Health policy evaluation (200205)
Health education and promotion (200203)
Dental health (200402)

Publications

Dr Laslett has published over 30 peer review publications, primarily in osteoarthritis epidemiology, knee pain, and clinical trials treating osteoarthritis pain. Two of her publications are in theLancet (IF 38.2) and sevenin the top Rheumatology journal Annals of the Rheumatic Diseases (IF 9.1).

Total publications

Highlighted publications

(1 outputs)

Year	Type	Citation	Altmetrics
2012	Journal Article	Laslett LL, Dore DA, Quinn SJ, Boon P, Ryan E, et al., 'Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial', Annals of the Rheumatic Diseases, 71, (8) pp. 1322-1328. ISSN 0003-4967 (2012) [Refereed Article] DOI: 10.1136/annrheumdis-2011-200970 [eCite] [Details] Citations: Scopus - 208Web of Science - 190 Co-authors: Dore DA; Boon P; Winzenberg TM; Jones G Tweet

Year

Type

Citation

Altmetrics

2012

Journal Article

Laslett LL, Dore DA, Quinn SJ, Boon P, Ryan E, et al., 'Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial', Annals of the Rheumatic Diseases, 71, (8) pp. 1322-1328. ISSN 0003-4967 (2012) [Refereed Article]

DOI: 10.1136/annrheumdis-2011-200970 [eCite] [Details]

Citations: Scopus - 208Web of Science - 190

Co-authors: Dore DA; Boon P; Winzenberg TM; Jones G

Journal Article

(84 outputs)

Year	Citation	Altmetrics
2023	Campbell JA, van der Mei I, Taylor BV, Palmer AJ, Henson GJ, et al., 'Using qualitative free-text data to investigate the lived experience of the COVID-19 pandemic for a large cohort of Australians with different multiple sclerosis related disability levels', Journal of Neurology, Neurosurgery and Psychiatry ISSN 0022-3050 (2023) [Refereed Article] [eCite] [Details] Co-authors: Campbell JA; van der Mei I; Taylor BV; Palmer AJ; Henson GJ; Simpson-Yap S; Claflin SB
2023	Li X, Wang Y, Ma Y, Pan F, Laslett L, et al., 'Longitudinal associations of body mass index and abdominal circumference with back pain among community-dwelling adults: data from the Osteoarthritis Initiative', The Spine Journal ISSN 1529-9430 (2023) [Refereed Article] DOI: 10.1016/j.spinee.2023.03.014 [eCite] [Details] Tweet
2023	Ma C, Pan F, Laslett LL, Wu F, Nguyen HH, et al., 'Associations between body composition, physical activity, and diet and radial bone microarchitecture in older adults: a 10-year population-based study', Archives of Osteoporosis, 18, (1) pp. 1-13. ISSN 1862-3514 (2023) [Refereed Article] DOI: 10.1007/s11657-022-01194-7 [eCite] [Details] Co-authors: Ma C; Pan F; Wu F; Winzenberg T; Jones G Tweet
2022	Cai G, Laslett LL, Bowes MA, Conaghan PG, Cicuttini F, et al., 'Effect of zoledronic acid with or without methylprednisolone on 3D bone area and bone shape in patients with symptomatic knee osteoarthritis: A post-hoc analysis of the ZAP2 trial', Seminars in Arthritis and Rheumatism, 56 Article 152054. ISSN 0049-0172 (2022) [Refereed Article] DOI: 10.1016/j.semarthrit.2022.152054 [eCite] [Details] Co-authors: Cai G; Winzenberg T; Jones G; Aitken D Tweet
2022	Campbell JA, Ahmad H, Chen G, van der Mei I, Taylor B, et al., 'Validation of the EQ-5D-5L and psychosocial bolt-ons in a large cohort of people living with multiple sclerosis in Australia', Quality of Life Research ISSN 0962-9343 (2022) [Refereed Article] DOI: 10.1007/s11136-022-03214-y [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Campbell JA; Ahmad H; van der Mei I; Taylor B; Claflin S; Henson GJ; Hawkes K; Hurst C; Waugh H; Palmer AJ Tweet
2022	Host LV, Keen HI, Laslett LL, Black DM, Jones G, 'Zoledronic acid does not slow spinal radiographic progression of osteoarthritis in postmenopausal women with osteoporosis and radiographic osteoarthritis', Therapeutic Advances in Musculoskeletal Disease, 14 Article 1759720X221081652. ISSN 1759-720X (2022) [Refereed Article] DOI: 10.1177/1759720X221081652 [eCite] [Details] Co-authors: Jones G Tweet
2022	Laslett LL, Honan C, Turner JA, Dagnew B, Campbell JA, et al., 'Poor sleep and multiple sclerosis: associations with symptoms of multiple sclerosis and quality of life', Journal of Neurology Neurosurgery and Psychiatry, 93 pp. 1162-1165. ISSN 0022-3050 (2022) [Refereed Article] DOI: 10.1136/jnnp-2022-329227 [eCite] [Details] Citations: Scopus - 2Web of Science - 2 Co-authors: Honan C; Turner JA; Campbell JA; Blizzard L; Taylor BV; van der Mei I Tweet
2022	Sutton L, Jose K, Hansen E, Laslett L, Makin K, et al., 'Navigating the maze of osteoarthritis treatment: A qualitative study exploring the experience of individuals with osteoarthritis in Tasmania, Australia', Musculoskeletal Care pp. 1-8. ISSN 1478-2189 (2022) [Refereed Article] DOI: 10.1002/msc.1700 [eCite] [Details] Co-authors: Sutton L; Jose K; Hansen E; Makin K; Winzenberg T; Balogun S; Aitken D Tweet
2022	Wang Zhiqiang, Singh Ambrish, Jones Graeme, Aitken D, Laslett LL, et al., 'Boswellia for osteoarthritis (Protocol)', Cochrane Database of Systematic Reviews, 2022, (10) pp. 1-16. ISSN 1469-493X (2022) [Refereed Article] DOI: 10.1002/14651858.CD014969 [eCite] [Details] Co-authors: Singh Ambrish; Jones Graeme; Aitken D; Ding C; Antony B Tweet
2022	Zhang X, Cai G, Jones G, Laslett LL, 'Intravenous bisphosphonates do not improve knee pain or bone marrow lesions in people with knee osteoarthritis: a meta-analysis', Rheumatology, 61, (6) pp. 2235-2242. ISSN 0080-2727 (2022) [Refereed Article] DOI: 10.1093/rheumatology/keab786 [eCite] [Details] Citations: Scopus - 2Web of Science - 5 Co-authors: Zhang X; Cai G; Jones G Tweet
2021	Aitken D, Balogun S, Foong Y, Humphries D, Laslett L, et al., 'Clinical relevance of MRI knee abnormalities in Australian rules football players: a longitudinal study', BMJ Open Sport & Exercise Medicine, 7, (3) ISSN 2055-7647 (2021) [Refereed Article] DOI: 10.1136/bmjsem-2021-001097 [eCite] [Details] Co-authors: Aitken D; Foong Y; Pitchford N; Khan H; Jones G; Winzenberg T Tweet
2021	Meng T, Wilson JE, Venn A, Cicuttini F, March L, et al., 'Association between diet quality in adolescence and adulthood and knee symptoms in adulthood: a 25-year cohort study', The British Journal of Nutrition ISSN 0007-1145 (2021) [Refereed Article] DOI: 10.1017/S0007114521002658 [eCite] [Details] Citations: Scopus - 2Web of Science - 1 Co-authors: Meng T; Wilson JE; Venn A; Blizzard L; Jones G; Eathakkattu Antony BS; Ding C Tweet
2021	Mezhov V, Laslett LL, Ahedi H, Blizzard CL, Aspden RM, et al., 'Predictors of total hip replacement in community based older adults: a cohort study', Osteoarthritis and Cartilage Article online ahead of print. ISSN 1063-4584 (2021) [Refereed Article] DOI: 10.1016/j.joca.2021.04.013 [eCite] [Details] Citations: Scopus - 2Web of Science - 1 Co-authors: Ahedi H; Blizzard CL; Cai G; Jones G Tweet
2021	Shah A, Wu F, Jones G, Cicuttini F, Toh LS, et al., 'The association between incident vertebral deformities, health-related quality of life and functional impairment: a 10.7-year cohort study', Osteoporosis International ISSN 0937-941X (2021) [Refereed Article] DOI: 10.1007/s00198-021-06004-3 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Shah A; Wu F; Jones G Tweet
2021	Sutton L, Jose K, Betzold A, Hansen E, Laslett L, et al., 'Understanding the management of osteoarthritis in Australia: a qualitative study of GPs and orthopaedic surgeons in Tasmania, Australia', Osteoarthritis and Cartilage Open, 3, (4) Article 100218. ISSN 2665-9131 (2021) [Refereed Article] DOI: 10.1016/j.ocarto.2021.100218 [eCite] [Details] Co-authors: Sutton L; Jose K; Betzold A; Hansen E; Makin J; Winzenberg T; Aitken D Tweet
2021	Wang Z, Singh A, Jones G, Winzenberg T, Ding C, et al., 'Efficacy and safety of turmeric extracts for the treatment of knee osteoarthritis: a systematic review and meta-analysis of randomised controlled trials', Current Rheumatology Reports, 23, (2) pp. 1-11. ISSN 1523-3774 (2021) [Refereed Article] DOI: 10.1007/s11926-020-00975-8 [eCite] [Details] Citations: Scopus - 15Web of Science - 13 Co-authors: Singh A; Jones G; Winzenberg T; Ding C; Antony B Tweet
2020	Cai G, Aitken D, Laslett LL, Hill C, Wluka AE, et al., 'The association between change in bone marrow lesion size and change in tibiofemoral cartilage volume and knee symptoms', Rheumatology, (November) pp. 1-10. ISSN 1462-0324 (2020) [Refereed Article] DOI: 10.1093/rheumatology/keaa716 [eCite] [Details] Citations: Scopus - 4Web of Science - 5 Co-authors: Cai G; Aitken D; Jones G Tweet
2020	Cai G, Aitken D, Laslett LL, Pelletier J-P, Martel-Pelletier J, et al., 'Effect of intravenous zoledronic acid on tibiofemoral cartilage volume among patients with knee osteoarthritis with bone marrow lesions: a randomized clinical trial', JAMA - Journal of the American Medical Association, 323, (15) pp. 1456-1466. ISSN 0098-7484 (2020) [Refereed Article] DOI: 10.1001/jama.2020.2938 [eCite] [Details] Citations: Scopus - 43Web of Science - 42 Co-authors: Cai G; Aitken D; Antony B; Blizzard L; Winzenberg T; Jones G Tweet
2020	Cai G, Cicuttini F, Aitken D, Laslett LL, Zhu Z, et al., 'Comparison of radiographic and MRI osteoarthritis definitions and their combination for prediction of tibial cartilage loss, knee symptoms and total knee replacement: a longitudinal study', Osteoarthritis and Cartilage, 28 pp. 1062-1070. ISSN 1063-4584 (2020) [Refereed Article] DOI: 10.1016/j.joca.2020.04.017 [eCite] [Details] Citations: Scopus - 5Web of Science - 4 Co-authors: Cai G; Aitken D; Winzenberg T; Jones G Tweet
2020	Cai G, Keen HI, Host LV, Aitken D, Laslett LL, et al., 'Once-yearly zoledronic acid and change in abdominal aortic calcification over 3 years in postmenopausal women with osteoporosis: results from the HORIZON Pivotal Fracture Trial', Osteoporosis International, 31, (9) pp. 1741-1747. ISSN 0937-941X (2020) [Refereed Article] DOI: 10.1007/s00198-020-05430-z [eCite] [Details] Citations: Scopus - 7Web of Science - 8 Co-authors: Cai G; Aitken D; Winzenberg T; Jones G Tweet
2020	Laslett LL, Antony B, Wluka AE, Hill C, March L, et al., 'KARAOKE: Krill oil versus placebo in the treatment of knee osteoarthritis: protocol for a randomised controlled trial', Trials, 21, (1) Article 79. ISSN 1745-6215 (2020) [Refereed Article] DOI: 10.1186/s13063-019-3915-1 [eCite] [Details] Citations: Scopus - 9Web of Science - 11 Co-authors: Antony B; Otahal P; Jones G Tweet
2020	Ma C, Pan F, Yang Y, Laslett L, Squibb K, et al., 'Distal radius bone microarchitecture: what are the differences between age 25 and old age?', Archives of Osteoporosis, 15, (1) Article 16. ISSN 1862-3522 (2020) [Refereed Article] DOI: 10.1007/s11657-020-0696-9 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Ma C; Pan F; Squibb K; Winzenberg T; Jones G Tweet
2020	Ma C, Wu F, Pan F, Laslett L, Shah A, et al., 'Bone microarchitecture, volumetric or areal bone mineral density for discrimination of vertebral deformity in adults: a cross-sectional study', Journal of Clinical Densitometry pp. 1-10. ISSN 1094-6950 (2020) [Refereed Article] DOI: 10.1016/j.jocd.2020.05.005 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Ma C; Wu F; Pan F; Shah A; Squibb K; Winzenberg T; Jones G Tweet
2020	Wang Z, Jones G, Winzenberg T, Cai G, Laslett LL, et al., 'Effectiveness of Curcuma longa extract for the treatment of symptoms and effusion-synovitis of knee osteoarthritis : a randomized trial', Annals of Internal Medicine, 173, (11) pp. 861-869. ISSN 0003-4819 (2020) [Refereed Article] DOI: 10.7326/M20-0990 [eCite] [Details] Citations: Scopus - 47Web of Science - 42 Co-authors: Jones G; Winzenberg T; Cai G; Aitken D; Singh A; Ding C; Antony B Tweet
2020	Zhang X, Ji S, Cai G, Pan Z, Han R, et al., 'H19 increases IL-17A/IL-23 releases via regulating VDR by interacting with miR675-5p/miR22-5p in ankylosing spondylitis', Molecular Therapy - Nucleic Acids, 19 pp. 393-404. ISSN 2162-2531 (2020) [Refereed Article] DOI: 10.1016/j.omtn.2019.11.025 [eCite] [Details] Citations: Scopus - 23Web of Science - 19 Co-authors: Zhang X; Cai G; Pan F Tweet
2019	Cai G, Laslett LL, Aitken D, Cicuttini F, March L, et al., 'Zoledronic acid plus methylprednisolone versus zoledronic acid or placebo in symptomatic knee osteoarthritis: a randomized controlled trial', Therapeutic Advances in Musculoskeletal Disease, 11 pp. 1-12. ISSN 1759-720X (2019) [Refereed Article] DOI: 10.1177/1759720X19880054 [eCite] [Details] Citations: Scopus - 5Web of Science - 5 Co-authors: Cai G; Aitken D; Winzenberg T; Jones G Tweet
2019	Mattap SM, Laslett LL, Squibb K, Wills K, Otahal P, et al., 'Hand examination, ultrasound and its association with hand pain and function in community-based older adults', Arthritis Care & Research pp. 1-28. ISSN 2151-464X (2019) [Refereed Article] DOI: 10.1002/acr.24128 [eCite] [Details] Citations: Scopus - 2 Co-authors: Mattap SM; Squibb K; Wills K; Otahal P; Pan F; Aitken D; Winzenberg T; Jones G Tweet
2019	Meng T, Antony B, Venn A, Eckstein F, Cicuttini F, et al., 'Association of body composition, physical activity and physical performance with knee cartilage thickness and bone area in young adults', Rheumatology pp. 1-10. ISSN 1462-0324 (2019) [Refereed Article] DOI: 10.1093/rheumatology/kez498 [eCite] [Details] Co-authors: Antony B; Venn A; Dwyer T; Blizzard L; Jones G; Ding C Tweet
2019	Meng T, Antony B, Venn A, Fraser B, Cicuttini F, et al., 'Association of glucose homeostasis and metabolic syndrome with knee cartilage defects and cartilage volume in young adults', Seminars in Arthritis and Rheumatism pp. 1-6. ISSN 0049-0172 (2019) [Refereed Article] DOI: 10.1016/j.semarthrit.2019.10.001 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Antony B; Venn A; Fraser B; Dwyer T; Jones G; Ding C Tweet
2018	Aitken D, Laslett LL, Cai G, Hill C, March L, et al., 'A protocol for a multicentre, randomised, double-blind, placebo-controlled trial to compare the effect of annual infusions of zoledronic acid to placebo on knee structural change and knee pain over 24 months in knee osteoarthritis patients - ZAP2', BMC Musculoskeletal Disorders, 19, (1) Article 217. ISSN 1471-2474 (2018) [Contribution to Refereed Journal] DOI: 10.1186/s12891-018-2143-2 [eCite] [Details] Citations: Scopus - 19Web of Science - 19 Co-authors: Aitken D; Cai G; Blizzard L; Jones G Tweet
2018	Aitken D, Laslett LL, Pan F, Haugen IK, Otahal P, et al., 'A randomised double-blind placebo-controlled crossover trial of HUMira (adalimumab) for erosive hand OsteoaRthritis - the HUMOR trial', Osteoarthritis and Cartilage, 26, (7) pp. 880-887. ISSN 1063-4584 (2018) [Refereed Article] DOI: 10.1016/j.joca.2018.02.899 [eCite] [Details] Citations: Scopus - 79Web of Science - 74 Co-authors: Aitken D; Pan F; Otahal P; Jones G Tweet
2018	Cai G, Laslett LL, Aitken D, Halliday A, Pan F, et al., 'Effect of Zoledronic Acid and Denosumab in patients with low back pain and modic change: A proof-of-principle trial', Journal of Bone and Mineral Research, 33, (5) pp. 773-782. ISSN 0884-0431 (2018) [Refereed Article] DOI: 10.1002/jbmr.3376 [eCite] [Details] Citations: Scopus - 26Web of Science - 23 Co-authors: Cai G; Aitken D; Pan F; Otahal P; Winzenberg TM; Jones G Tweet
2018	Laslett LL, Menz HB, Otahal P, Pan F, Cicuttini FM, et al., 'Factors associated with prevalent and incident foot pain: data from the Tasmanian Older Adult Cohort Study', Maturitas, 118 pp. 38-43. ISSN 0378-5122 (2018) [Refereed Article] DOI: 10.1016/j.maturitas.2018.10.004 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 Co-authors: Otahal P; Pan F; Jones G Tweet
2018	Mattap SM, Aitken D, Wills K, Halliday A, Ding C, et al., 'Patellar tendon enthesis abnormalities and their association with knee pain and structural abnormalities in older adults', Osteoarthritis and Cartilage, 27, (3) pp. 449-458. ISSN 1063-4584 (2018) [Refereed Article] DOI: 10.1016/j.joca.2018.11.009 [eCite] [Details] Citations: Scopus - 5Web of Science - 4 Co-authors: Mattap SM; Aitken D; Wills K; Ding C; Han W; Munugoda I; Jones G Tweet
2018	Mattap SM, Aitken D, Wills K, Laslett L, Ding C, et al., 'How do MRI-detected subchondral bone marrow lesions (BMLs) on two different MRI sequences correlate with clinically important outcomes?', Calcified Tissue International, 103, (2) pp. 131-143. ISSN 0171-967X (2018) [Refereed Article] DOI: 10.1007/s00223-018-0402-8 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Mattap SM; Aitken D; Wills K; Ding C; Jones G Tweet
2018	Meng T, Thayer S, Venn A, Wu F, Cicuttini F, et al., 'Association of childhood adiposity measures with adulthood knee cartilage defects and bone marrow lesions: a 25-year cohort study', Osteoarthritis and Cartilage, 26, (8) pp. 1055-1062. ISSN 1063-4584 (2018) [Refereed Article] DOI: 10.1016/j.joca.2018.05.008 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 Co-authors: Venn A; Wu F; Dwyer T; Jones G; Ding C; Antony B Tweet
2018	Meng T, Venn A, Eckstein F, Wirth W, Cicuttini F, et al., 'Association of adiposity measures in childhood and adulthood with knee cartilage thickness, volume and bone area in young adults', International Journal of Obesity pp. 1-11. ISSN 0307-0565 (2018) [Refereed Article] DOI: 10.1038/s41366-018-0234-7 [eCite] [Details] Citations: Scopus - 5Web of Science - 5 Co-authors: Venn A; Dwyer T; Jones G; Ding C; Antony B Tweet
2018	Tatangelo G, Watts J, Lim K, Connaughton C, Abimanyi-Ochom J, et al., 'The cost of osteoporosis, osteopenia, and associated fractures in Australia in 2017', Journal of Bone and Mineral Research pp. 1-10. ISSN 0884-0431 (2018) [Refereed Article] DOI: 10.1002/jbmr.3640 [eCite] [Details] Citations: Scopus - 58Web of Science - 54 Co-authors: Winzenberg T Tweet
2018	Wu F, Wills K, Laslett LL, Riley MD, Oldenburg B, et al., 'Individualized fracture risk feedback and long-term benefits after 10 years', American Journal of Preventive Medicine, 54, (2) pp. 266-274. ISSN 0749-3797 (2018) [Refereed Article] DOI: 10.1016/j.amepre.2017.10.018 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 Co-authors: Wu F; Wills K; Jones G; Winzenberg T Tweet
2017	Pan F, Laslett L, Blizzard L, Cicuttini F, Winzenberg T, et al., 'Associations between fat mass and multi-site pain: A 5-year longitudinal study', Arthritis Care & Research, 69, (4) pp. 509-516. ISSN 2151-464X (2017) [Refereed Article] DOI: 10.1002/acr.22963 [eCite] [Details] Citations: Scopus - 24Web of Science - 27 Co-authors: Pan F; Blizzard L; Winzenberg T; Ding C; Jones G Tweet
2017	Pan F, Laslett L, Tian J, Cicuttini F, Winzenberg T, et al., 'Association Between Pain at Sites Outside the Knee and Knee Cartilage Volume Loss in Elderly People Without Knee Osteoarthritis: A Prospective Study', Arthritis Care & Research, 69, (5) pp. 659-666. ISSN 2151-464X (2017) [Refereed Article] DOI: 10.1002/acr.22964 [eCite] [Details] Citations: Scopus - 6Web of Science - 7 Co-authors: Pan F; Tian J; Winzenberg T; Ding C; Jones G Tweet
2017	Warner SC, Walsh DA, Laslett LL, Maciewicz RA, Soni A, et al., 'Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR1) gene', European Journal of Pain, 21, (7) pp. 1277-1284. ISSN 1090-3801 (2017) [Refereed Article] DOI: 10.1002/ejp.1027 [eCite] [Details] Citations: Scopus - 21Web of Science - 18 Co-authors: Jones G Tweet
2017	Wu F, Callisaya M, Wills K, Laslett LL, Jones G, et al., 'Both baseline and change in lower limb muscle strength in younger women are independent predictors of balance in middle age: A 12-Year population-based prospective study', Journal of Bone and Mineral Research, 32, (6) pp. 1201-1208. ISSN 0884-0431 (2017) [Refereed Article] DOI: 10.1002/jbmr.3103 [eCite] [Details] Citations: Scopus - 7Web of Science - 8 Co-authors: Wu F; Callisaya M; Wills K; Jones G; Winzenberg T Tweet
2017	Wu F, Wills K, Laslett LL, Oldenburg B, Jones G, et al., 'Moderate-to-vigorous physical activity but not sedentary time is associated with musculoskeletal health outcomes in a cohort of Australian middle-aged women', Journal of Bone and Mineral Research, 32, (4) pp. 708-715. ISSN 0884-0431 (2017) [Refereed Article] DOI: 10.1002/jbmr.3028 [eCite] [Details] Citations: Scopus - 31Web of Science - 32 Co-authors: Wu F; Wills K; Jones G; Winzenberg T Tweet
2017	Wu F, Wills K, Laslett LL, Oldenburg B, Jones G, et al., 'Associations of dietary patterns with bone mass, muscle strength and balance in a cohort of Australian middle-aged women', British Journal of Nutrition, 118, (8) pp. 598-606. ISSN 0007-1145 (2017) [Refereed Article] DOI: 10.1017/S0007114517002483 [eCite] [Details] Citations: Scopus - 27Web of Science - 25 Co-authors: Wu F; Wills K; Jones G; Winzenberg T Tweet
2017	Wu F, Wills K, Laslett LL, Oldenburg B, Seibel MJ, et al., 'Cut-points for associations between vitamin D status and multiple musculoskeletal outcomes in middle-aged women', Osteoporosis International, 28, (2) pp. 505-515. ISSN 0937-941X (2017) [Refereed Article] DOI: 10.1007/s00198-016-3754-9 [eCite] [Details] Citations: Scopus - 17Web of Science - 14 Co-authors: Wu F; Wills K; Jones G; Winzenberg T Tweet
2017	Zhu Z, Laslett LL, Han W, Antony B, Pan F, et al., 'Associations between MRI-detected early osteophytes and knee structure in older adults: a population-based cohort study', Osteoarthritis and Cartilage, 25, (12) pp. 2055-2062. ISSN 1063-4584 (2017) [Refereed Article] DOI: 10.1016/j.joca.2017.09.005 [eCite] [Details] Citations: Scopus - 8Web of Science - 8 Co-authors: Zhu Z; Han W; Antony B; Pan F; Jones G; Ding C Tweet
2017	Zhu Z, Laslett LL, Jin X, Han W, Antony B, et al., 'Association between MRI-detected osteophytes and changes in knee structures and pain in older adults: a cohort study', Osteoarthritis and Cartilage, 25, (7) pp. 1084-1092. ISSN 1063-4584 (2017) [Refereed Article] DOI: 10.1016/j.joca.2017.01.007 [eCite] [Details] Citations: Scopus - 17Web of Science - 16 Co-authors: Zhu Z; Jin X; Han W; Antony B; Lu M; Jones G; Ding C Tweet
2017	Zhu Z, Otahal P, Wang B, Jin X, Laslett LL, et al., 'Cross-sectional and longitudinal associations between serum inflammatory cytokines and knee bone marrow lesions in patients with knee osteoarthritis', Osteoarthritis and Cartilage, 25, (4) pp. 499-505. ISSN 1063-4584 (2017) [Refereed Article] DOI: 10.1016/j.joca.2016.10.024 [eCite] [Details] Citations: Scopus - 25Web of Science - 25 Co-authors: Zhu Z; Otahal P; Jin X; Antony B; Han W; Winzenberg TM; Jones G; Ding C Tweet
2016	Hall J, Laslett LL, Martel-Pelletier J, Pelletier JP, Abram F, et al., 'Change in knee structure and change in tibiofemoral joint space width: a five year longitudinal population-based study', BMC Musculoskeletal Disorders, 17 Article 25. ISSN 1471-2474 (2016) [Refereed Article] DOI: 10.1186/s12891-016-0879-0 [eCite] [Details] Citations: Scopus - 6Web of Science - 6 Co-authors: Hall J; Ding CH; Jones G Tweet
2016	Jin X, Ding C, Wang X, Antony B, Laslett LL, et al., 'Longitudinal associations between adiposity and change in knee pain: Tasmanian older adult cohort study', Seminars in Arthritis and Rheumatism, 45, (5) pp. 564-569. ISSN 0049-0172 (2016) [Refereed Article] DOI: 10.1016/j.semarthrit.2015.10.006 [eCite] [Details] Citations: Scopus - 11Web of Science - 10 Co-authors: Jin X; Ding C; Antony B; Blizzard L; Jones G Tweet
2016	Laslett LL, Otahal P, Hensor EMA, Kingsbury SR, Conaghan PG, 'Knee pain predicts subsequent shoulder pain and the association is mediated by leg weakness: Longitudinal observational data from the osteoarthritis initiative', Journal of Rheumatology, 43, (11) pp. 2049-2055. ISSN 0315-162X (2016) [Refereed Article] DOI: 10.3899/jrheum.160001 [eCite] [Details] Citations: Scopus - 7Web of Science - 6 Co-authors: Otahal P Tweet
2016	Laslett LL, Pelletier J-P, Cicuttini FM, Jones G, Martel-Pelletier J, 'Measuring Disease Progression in Osteoarthritis', Current Treatment Options in Rheumatology, 2, (2) pp. 97-110. ISSN 2198-6002 (2016) [Refereed Article] DOI: 10.1007/s40674-016-0041-z [eCite] [Details] Co-authors: Jones G Tweet
2016	Rogers JA, Wilson A, Laslett LL, Winzenberg TM, 'Physical interventions (orthoses, splints, exercise and manual therapy) for treating plantar heel pain', Cochrane Database of Systematic Reviews, 2016, (8) Article CD012304. ISSN 1469-493X (2016) [Refereed Article] DOI: 10.1002/14651858.CD012304 [eCite] [Details] Citations: Scopus - 1 Co-authors: Rogers JA; Wilson A; Winzenberg TM Tweet
2016	Scott D, Chandrasekara SD, Laslett LL, Cicuttini F, Ebeling PR, et al., 'Associations of Sarcopenic Obesity and Dynapenic Obesity with Bone Mineral Density and Incident Fractures Over 5-10 Years in Community-Dwelling Older Adults', Calcified Tissue International, 99, (1) pp. 30-42. ISSN 0171-967X (2016) [Refereed Article] DOI: 10.1007/s00223-016-0123-9 [eCite] [Details] Citations: Scopus - 88Web of Science - 81 Co-authors: Jones G Tweet
2016	Wu F, Callisaya M, Laslett LL, Wills K, Zhou Y, et al., 'Lower limb muscle strength is associated with poor balance in middle-aged women: linear and nonlinear analyses', Osteoporosis International, 27, (7) pp. 2241-2248. ISSN 0937-941X (2016) [Refereed Article] DOI: 10.1007/s00198-016-3545-3 [eCite] [Details] Citations: Scopus - 12Web of Science - 10 Co-authors: Wu F; Callisaya M; Wills K; Zhou Y; Jones G; Winzenberg T Tweet
2016	Zhu Z, Ding C, Jin X, Eathakkattu Antony BS, Han W, et al., 'Patellofemoral bone marrow lesions: natural history and associations with pain and structure', Arthritis Care & Research, 68, (11) pp. 1647-1654. ISSN 2151-464X (2016) [Refereed Article] DOI: 10.1002/acr.22871 [eCite] [Details] Citations: Scopus - 7Web of Science - 7 Co-authors: Zhu Z; Ding C; Jin X; Eathakkattu Antony BS; Han W; Jones G Tweet
2016	Zhu Z, Jin X, Wang B, Wluka A, Antony B, et al., 'Cross-sectional and longitudinal associations between serum levels of high-sensitivity C-reactive protein, knee bone marrow lesions, and knee pain in patients with knee osteoarthritis', Arthritis Care & Research, 68, (10) pp. 1471-1477. ISSN 2151-464X (2016) [Refereed Article] DOI: 10.1002/acr.22834 [eCite] [Details] Citations: Scopus - 14Web of Science - 14 Co-authors: Zhu Z; Jin X; Antony B; Winzenberg T; Jones G; Ding C Tweet
2015	Abimanyi-Ochom J, Watts JJ, Borgstrom F, Nicholson GC, Shore-Lorenti C, et al., 'Changes in quality of life associated with fragility fractures: Australian arm of the International Cost and Utility Related to Osteoporotic Fractures Study (AusICUROS)', Osteoporosis International, 26, (6) pp. 1-10. ISSN 0937-941X (2015) [Refereed Article] DOI: 10.1007/s00198-015-3088-z [eCite] [Details] Citations: Scopus - 70Web of Science - 63 Co-authors: Winzenberg T Tweet
2015	Cai J, Xu J, Wang K, Zheng S, He F, et al., 'Association between infrapatellar fat pad volume and knee structural changes in patients with knee osteoarthritis', Journal of Rheumatology, 42, (10) pp. 1878-1884. ISSN 0315-162X (2015) [Refereed Article] DOI: 10.3899/jrheum.150175 [eCite] [Details] Citations: Scopus - 60Web of Science - 57 Co-authors: Ding C Tweet
2015	Laslett LL, Jin X, Jones G, 'Efficacy and safety of plant-derived products for the treatment of osteoarthritis', Botanics: Targets and Therapy, 5 pp. 1-20. ISSN 1179-9897 (2015) [Refereed Article] DOI: 10.2147/BTAT.S33431 [eCite] [Details] Co-authors: Jin X; Jones G Tweet
2015	Wu F, Laslett LL, Zhang Q, 'Threshold effects of vitamin D status on bone health in Chinese adolescents with low calcium intake', Journal of Clinical Endocrinology and Metabolism, 100, (12) pp. 4481-4489. ISSN 1945-7197 (2015) [Refereed Article] DOI: 10.1210/jc.2015-2849 [eCite] [Details] Citations: Scopus - 10Web of Science - 8 Co-authors: Wu F Tweet
2014	Cross M, Smith E, Hoy D, Nolte S, Ackerman I, et al., 'The global burden of hip and knee osteoarthritis: Estimates from the Global Burden of Disease 2010 study', Annals of the Rheumatic Diseases, 73, (7) pp. 1323-1330. ISSN 0003-4967 (2014) [Refereed Article] DOI: 10.1136/annrheumdis-2013-204763 [eCite] [Details] Citations: Scopus - 1990Web of Science - 1898 Co-authors: Jones G Tweet
2014	Jones G, Winzenberg TM, Callisaya ML, Laslett LL, 'Lifestyle modifications to improve musculoskeletal and bone health and reduce disability - A life-course approach', Best Practice & Research: Clinical Rheumatology, 28, (3) pp. 461-478. ISSN 1532-1770 (2014) [Refereed Article] DOI: 10.1016/j.berh.2014.07.004 [eCite] [Details] Citations: Scopus - 8Web of Science - 9 Co-authors: Jones G; Winzenberg TM; Callisaya ML Tweet
2014	Laslett LL, Kingsbury SR, Hensor EMA, Bowes MA, Conaghan PG, 'Effect of bisphosphonate use in patients with symptomatic and radiographic knee osteoarthritis: data from the Osteoarthritis Initiative', Annals of the Rheumatic Diseases, 73, (5) pp. 824-830. ISSN 1468-2060 (2014) [Refereed Article] DOI: 10.1136/annrheumdis-2012-202989 [eCite] [Details] Citations: Scopus - 51Web of Science - 44 Tweet
2014	Laslett LL, Quinn S, Burgess JR, Parameswaran V, Winzenberg TM, et al., 'Moderate vitamin D deficiency is associated with changes in knee and hip pain in older adults: a 5-year longitudinal study', Annals of the Rheumatic Diseases, 73, (4) pp. 697-703. ISSN 1468-2060 (2014) [Refereed Article] DOI: 10.1136/annrheumdis-2012-202831 [eCite] [Details] Citations: Scopus - 62Web of Science - 53 Co-authors: Burgess JR; Winzenberg TM; Jones G; Ding C Tweet
2014	Liu S, Liu L, Wu S, Yang T, Pan F, et al., 'Lack of Association Between TESPA1 Gene Polymorphisms (rs1801876, rs2171497, rs4758994, and rs997173) and Ankylosing Spondylitis in a Chinese Population', Inflammation, 37, (6) pp. 2040-2046. ISSN 0360-3997 (2014) [Refereed Article] DOI: 10.1007/s10753-014-9936-8 [eCite] [Details] Citations: Scopus - 1 Tweet
2014	Neogi T, Soni A, Doherty SA, Laslett LL, Maciewicz RA, et al., 'Contribution of the COMT Val158Met variant to symptomatic knee osteoarthritis', Annals of the Rheumatic Diseases: The Euler Journal, 73, (1) pp. 315-317. ISSN 1468-2060 (2014) [Refereed Article] DOI: 10.1136/annrheumdis-2013-203836 [eCite] [Details] Citations: Scopus - 15Web of Science - 12 Co-authors: Jones G Tweet
2014	Wu F, Laslett LL, Wills K, Oldenburg B, Jones G, et al., 'Effects of Individualized Bone Density Feedback and Educational Interventions on Osteoporosis Knowledge and Self-Efficacy: A 12-Yr Prospective Study', Journal of Clinical Densitometry, 17, (4) pp. 466-472. ISSN 1094-6950 (2014) [Refereed Article] DOI: 10.1016/j.jocd.2014.07.008 [eCite] [Details] Citations: Scopus - 21Web of Science - 19 Co-authors: Wu F; Wills K; Jones G; Winzenberg T Tweet
2013	Panoutsopoulou K, Metrustry S, Doherty SA, Laslett LL, Maciewicz RA, et al., 'The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a mendelian randomisation study', Annals of the Rheumatic Diseases, 73, (12) pp. 2082-2086. ISSN 1468-2060 (2013) [Refereed Article] DOI: 10.1136/annrheumdis-2013-203772 [eCite] [Details] Citations: Scopus - 44Web of Science - 40 Co-authors: Jones G Tweet
2012	Crisp A, Dixon T, Jones G, Cumming RG, Laslett LL, et al., 'Declining incidence of osteoporotic hip fracture in Australia', Archives of Osteoporosis, 7, (1-2) pp. 179-185. ISSN 1862-3522 (2012) [Refereed Article] DOI: 10.1007/s11657-012-0095-y [eCite] [Details] Citations: Scopus - 37 Co-authors: Jones G Tweet
2012	Laslett LL, Dore DA, Quinn SJ, Boon P, Ryan E, et al., 'Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial', Annals of the Rheumatic Diseases, 71, (8) pp. 1322-1328. ISSN 0003-4967 (2012) [Refereed Article] DOI: 10.1136/annrheumdis-2011-200970 [eCite] [Details] Citations: Scopus - 208Web of Science - 190 Co-authors: Dore DA; Boon P; Winzenberg TM; Jones G Tweet
2012	Laslett LL, Just SJ, Quinn SJ, Winzenberg TM, Jones G, 'Excess body fat is associated with higher risk of vertebral deformities in older women but not in men: a cross-sectional study', Osteoporosis International, 23, (1) pp. 67-74. ISSN 1433-2965 (2012) [Refereed Article] DOI: 10.1007/s00198-011-1741-8 [eCite] [Details] Citations: Scopus - 57Web of Science - 52 Co-authors: Just SJ; Winzenberg TM; Jones G Tweet
2012	Laslett LL, Quinn SJ, Darian-Smith E, Kwok M, Fedorova T, et al., 'Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial', Osteoarthritis and Cartilage: Journal of The Osteoarthritis Research Society International, 20, (11) pp. 1209-1216. ISSN 1063-4584 (2012) [Refereed Article] DOI: 10.1016/j.joca.2012.07.019 [eCite] [Details] Citations: Scopus - 16Web of Science - 16 Co-authors: Darian-Smith E; Korner H; Jones G Tweet
2012	Laslett LL, Quinn SJ, Winzenberg TM, Sanderson K, Cicuttini F, et al., 'A prospective study of the impact of musculoskeletal pain and radiographic osteoarthritis on health related quality of life in community dwelling older people', BMC Musculoskeletal Disorders, 13 Article 168. ISSN 1471-2474 (2012) [Refereed Article] DOI: 10.1186/1471-2474-13-168 [eCite] [Details] Citations: Scopus - 57Web of Science - 54 Co-authors: Quinn SJ; Winzenberg TM; Sanderson K; Jones G Tweet
2012	Murray CJL, Vos T, Lozano R, Naghavi M, Flaxman AD, et al., 'Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010', Lancet, 380, (9859) pp. 2197-2223. ISSN 0140-6736 (2012) [Refereed Article] DOI: 10.1016/S0140-6736(12)61689-4 [eCite] [Details] Citations: Scopus - 6407Web of Science - 5641 Tweet
2012	Redmond CL, Bain GI, Laslett LL, McNeil JD, 'Deteriorating tactile sensation in patients with hand syndromes associated with diabetes: a two-year observational study', Journal of Diabetes and Its Complications, 26, (4) pp. 313-318. ISSN 1056-8727 (2012) [Refereed Article] DOI: 10.1016/j.jdiacomp.2012.04.009 [eCite] [Details] Citations: Scopus - 15Web of Science - 14 Tweet
2012	Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, et al., 'Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010', Lancet, 380, (9859) pp. 2163-2196. ISSN 0140-6736 (2012) [Refereed Article] DOI: 10.1016/S0140-6736(12)61729-2 [eCite] [Details] Citations: Scopus - 5638Web of Science - 4371 Tweet
2011	Laslett LL, Lynch J, Sullivan TR, McNeil JD, 'Osteoporosis education improves osteoporosis knowledge and dietary calcium: comparison of a 4 week and a one-session education course', International Journal of Rheumatic Diseases, 14, (3) pp. 239-247. ISSN 1756-1841 (2011) [Refereed Article] DOI: 10.1111/j.1756-185X.2011.01628.x [eCite] [Details] Citations: Scopus - 28Web of Science - 22 Tweet
2011	Valdes AM, De Wilde G, Doherty SA, Lories RJ, Vaughn FL, et al., 'The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis', Annals of The Rheumatic Diseases: The Eular Journal, 70, (9) pp. 1556-1561. ISSN 0003-4967 (2011) [Refereed Article] DOI: 10.1136/ard.2010.148122 [eCite] [Details] Citations: Scopus - 100Web of Science - 86 Co-authors: Jones G Tweet
2011	Wei S, Venn A, Ding C, Foley S, Laslett L, et al., 'The association between oral contraceptive use, bone mineral density and fractures in women aged 50-80 years', Contraception, 84, (4) pp. 357-362. ISSN 0010-7824 (2011) [Refereed Article] DOI: 10.1016/j.contraception.2011.02.001 [eCite] [Details] Citations: Scopus - 12Web of Science - 11 Co-authors: Wei S; Venn A; Ding C; Foley S; Jones G Tweet
2010	Wei S, Winzenberg T, Laslett LL, Venn A, Jones G, 'Oral contraceptive use and bone', Current Osteoporosis Reports , 9, (1) pp. 6-11. ISSN 1544-2241 (2010) [Refereed Article] DOI: 10.1007/s11914-010-0037-9 [eCite] [Details] Citations: Scopus - 18 Co-authors: Wei S; Winzenberg T; Venn A; Jones G Tweet
2009	Redmond CL, Bain GI, Laslett LL, McNeil JD, 'Hand syndromes associated with diabetes: impairments and obesity predict disability', Journal of Rheumatology, 36, (12) pp. 2766-2771. ISSN 0315-162X (2009) [Refereed Article] DOI: 10.3899/jrheum.090239 [eCite] [Details] Citations: Scopus - 30Web of Science - 27 Tweet
2008	Laslett LL, Burnet SP, Redmond CL, McNeil JD, 'Predictors of shoulder pain and shoulder disability after one year in diabetic outpatients', Rheumatology, 47, (10) pp. 1583-1586. ISSN 1462-0324 (2008) [Refereed Article] DOI: 10.1093/rheumatology/ken333 [eCite] [Details] Citations: Scopus - 25Web of Science - 21 Tweet

Chapter in Book

(1 outputs)

Year	Citation	Altmetrics
2014	Laslett LL, Jones G, 'Capsaicin for Osteoarthritis Pain', Capsaicin as a Therapeutic Molecule, Springer, Abdel-Salam, Omar M.E (ed), Basel, pp. 277-291. ISBN 978-3-0348-0828-6 (2014) [Research Book Chapter] DOI: 10.1007/978-3-0348-0828-6_11 [eCite] [Details] Citations: Scopus - 56 Co-authors: Jones G Tweet

Year

Citation

Altmetrics

2014

Laslett LL, Jones G, 'Capsaicin for Osteoarthritis Pain', Capsaicin as a Therapeutic Molecule, Springer, Abdel-Salam, Omar M.E (ed), Basel, pp. 277-291. ISBN 978-3-0348-0828-6 (2014) [Research Book Chapter]

DOI: 10.1007/978-3-0348-0828-6_11 [eCite] [Details]

Citations: Scopus - 56

Co-authors: Jones G

Conference Publication

(4 outputs)

Year	Citation	Altmetrics
2022	Campbell JA, Ahmad H, Chen G, Claflin S, Taylor BV, et al., 'Investigating health-related quality of life impacts for participants of the Australian MS Longitudinal Study using the new EQ-5D-5L Psychosocial instrument', Multiple Sclerosis Journal, pp. 18-19. ISSN 1352-4585 (2022) [Conference Extract] [eCite] [Details] Co-authors: Campbell JA; Ahmad H; Claflin S; Taylor BV; van der Mei I; Henson G; Palmer AJ
2022	Campbell JA, Ahmad H, Claflin S, Taylor BV, van der Mei I, et al., 'Assessing health-related quality-of-life in Australian Multiple Sclerosis Longitudinal Study participants using six multi-attribute utility instruments: implications for healthcare decision-making', Multiple Sclerosis Journal, pp. 19. ISSN 1352-4585 (2022) [Conference Extract] [eCite] [Details] Co-authors: Campbell JA; Ahmad H; Claflin S; Taylor BV; van der Mei I; Henson G; Palmer AJ
2020	Aitken D, Humphries D, Laslett L, Pitchford N, Khan HI, et al., 'Magnetic resonance imaging (MRI)-assessed knee abnormalities in Australian rules football players - AFL tas knee study', Osteoarthritis and Cartilage ISSN 1063-4584 (2020) [Conference Extract] [eCite] [Details] Co-authors: Aitken D; Pitchford N; Khan HI; Jones G; Winzenberg T
2017	Foong Y, Aitken D, Humphries D, Laslett L, Pitchford N, et al., 'Knee function, pain and magnetic resonance imaging abnormalities in Australian Rules Football players: a cohort study', Internal Medicine Journal ISSN 1444-0903 (2017) [Conference Extract] DOI: 10.1111/imj.5_13463 [eCite] [Details] Co-authors: Foong Y; Aitken D; Pitchford N; Khan H; Jones G; Winzenberg T Tweet

Grants & Funding

Dr Laslett has received over $170,000 in competitive grant funding.These include grants for the Modic back pain trial from the Tasmanian Community Fund ($88,721.10, 2014) and Arthritis Australia ($30,000, 2013).

Funding Summary

Number of grants

Total funding

$1,449,150

Projects

Providing high-value care for osteoarthritis patients at the Royal Hobart Hospital (RHH) (2020)$12,940

Description: This prospective, observational study will recruit patients undergoing primary elective hip or knee joint replacement at study sites in Tasmania. Participants will complete patient reported outcome measure (PROMs) surveys and have accelerometry data collected preoperatively and at 6 weeks, 12 weeks, 6 months and 12 months post-operatively. The trajectory of their recovery is measured both by their subjective PROMs responses and objective movement data captured by accelerometry to provide insights into expected performance changes and evaluate PROMs characteristics.The project aims to quantify physical performance changes that occur in patients following hip or knee arthroplasty and compare the relationship between this objective data and subjective PROMs.
Funding: The MPST Foundation Ltd ($12,940)
Scheme: Grant
Administered By: University of Tasmania
Research Team: Aitken D; Laslett LL; Harvie P; Haward CP
Year: 2020

A randomised trial of krill oil for osteoarthritis of the knee (2019)$100,000

Description: This project is additional funding to NHMRC Grant J23281Knee osteoarthritis (OA) is a significant and increasing cause of pain and disability in the aging Australian population, but interventions aimed at structural modification have been disappointing. Pilot data shows that krill oil reduces knee pain and systemic inflammation after 30 days, suggesting that an approach targeted at specific mechanisms of disease is effective in reducing painful OA. However, this pilot study was short, did not collect any data on structural factors, and included patients with a variety of disorders.We aim to compare, using a randomised, placebo-controlled double-blind design over six months, the efficacy of krill oil vs placebo in the treatment of osteoarthritis (OA) of the knee in 260 patients with clinical knee OA, significant knee pain and effusions, both with regard to control of symptoms and localised inflammation.Key hypothesis: Krill oil decreases pain (assessed by 100mm VAS) by 10mm more than identical placebo over 24 weeks in patients with clinical knee OA, significant knee pain and effusions.Secondary hypotheses: Krill oil improves knee pain over 4, 8, 12, 16, and 20 weeks in patients with clinical knee OA.Krill oil decreases effusion size by 20% over 24 weeks in patients with symptomatic osteoarthritis of the knee and knee effusion.If krill oil can both improve symptoms and decrease effusion in OA it has the potential to slow progression to joint replacement. The proposed study represents an innovative approach to this and lends itself to easy implementation as krill oil is already available over-the-counter in Australian pharmacies.
Funding: Aker BioMarine ($100,000)
Scheme: Contract Research
Administered By: University of Tasmania
Research Team: Jones G; Wluka A; Hill C; March L; Keen H; Laslett LL
Year: 2019

Assessing the Australian osteoarthritis landscape - GPs' surgeons' and patients attitudes towards and understandings of osteoarthritis (2018)$24,824

Description: Osteoarthritis is a leading cause of pain and disability among older people and there is currently no cure. In recent years, there has been increasing concern about the discrepancies between care provided by health professionals and recommendations in osteoarthritis clinical practice guideline. For instance, in Australia, referral to a surgeon is five times more common than referral to allied health professionals that could help with conservative management. Furthermore, patients are ambivalent towards conservative management such as exercise, thinking it will be ineffective and may even cause harm to their already worn joints. The disconnect between practice guideline and care for patients with osteoarthritis limits optimal care. Therefore, this study aims to explore the attitudes towards and understanding of osteoarthritis held by Australian GPs, surgeons and patients with knee osteoarthritis. The overarching goal is to gather information needed to develop Australian-specific education and behaviour change programs for GPs, surgeons and osteoarthritis patients
Funding: University of Tasmania ($24,824)
Scheme: Grant- Research Enhancement Program
Administered By: University of Tasmania
Research Team: Balogun S; Aitken D; Winzenberg TM; Hansen EC; Newsham-West H; Laslett LL
Year: 2018

Is the use of thermocyclopad effective for knee pain? (2016)$50,336

Description: Clinical trial to assess the efficacy daily use of the Niagara Thermo Cyclo Pad unit on the heat and vibrate settings, or the heat and vibrate settings plus use of the hand held unit will reduce knee pain, stiffness and symptoms over four weeks compared to the sham pad, for knee OA pain, function and stiffness.
Funding: CT Healthcare Pty Ltd ($50,336)
Scheme: Clinical Trial
Administered By: University of Tasmania
Research Team: Jones G; Laslett LL
Year: 2016

A randomised trial of krill oil for osteoarthritis of the knee (2016 - 2018)$751,491

Description: Knee osteoarthritis (OA) is a significant and increasing cause of pain and disability in the aging Australian population, but interventions aimed at structural modification have been disappointing. Pilot data shows that krill oil reduces knee pain and systemic inflammation after 30 days, suggesting that an approach targeted at specific mechanisms of disease is effective in reducing painful OA. However, this pilot study was short, did not collect any data on structural factors, and included patients with a variety of disorders.We aim to compare, using a randomised, placebo-controlled double-blind design over six months, the efficacy of krill oil vs placebo in the treatment of osteoarthritis (OA) of the knee in 260 patients with clinical knee OA, significant knee pain and effusions, both with regard to control of symptoms and localised inflammation.Key hypothesis: Krill oil decreases pain (assessed by 100mm VAS) by 10mm more than identical placebo over 24 weeks in patients with clinical knee OA, significant knee pain and effusions.Secondary hypotheses: Krill oil improves knee pain over 4, 8, 12, 16, and 20 weeks in patients with clinical knee OA.Krill oil decreases effusion size by 20% over 24 weeks in patients with symptomatic osteoarthritis of the knee and knee effusion.If krill oil can both improve symptoms and decrease effusion in OA it has the potential to slow progression to joint replacement. The proposed study represents an innovative approach to this and lends itself to easy implementation as krill oil is already available over-the-counter in Australian pharmacies.
Funding: National Health & Medical Research Council ($751,491)
Scheme: Grant-Project
Administered By: University of Tasmania
Research Team: Jones G; Wluka A; Hill C; March L; Keen H; Laslett LL
Period: 2016 - 2018
Grant Reference: 1102732

The effect of krill oil on cartilage composition (2016)$30,000

Description: Aims: to compare efficacy of krill oil vs identical placebo on cartilage composition (T2 mapping values) in 260patients with clinical knee OA, significant knee pain and effusion on imaging, using a randomised, placebo-controlled double-blind design over six months in an NHMRC-funded clinical trial.
Funding: Menzies Institute for Medical Research ($30,000)
Scheme: Grant - Development Grant
Administered By: University of Tasmania
Research Team: Laslett LL; Eathakkattu Antony BS; Aitken D
Year: 2016

Clinical trials in osteoarthritis (2014 - 2017)$304,596

Funding: National Health & Medical Research Council ($304,596)
Scheme: Fellowship-Early Career
Administered By: University of Tasmania
Research Team: Laslett LL
Period: 2014 - 2017
Grant Reference: 1070586

Does either zoledronic acid or denosumab change back pain and morphology of Modic changes: a randomised open label pilot study (2014)$30,000

Description: This research aims to determine whether two different bone active medications (zoledronic acid 5mg; denosumab 60mg) will modify back pain and structural abnormalities over six months in people with severe back pain and certain changes on magnetic resonance imaging (MRI). This will allow us to decide whether these medications have a large enough effect to warrant further clinical study.
Funding: Arthritis Australia ($30,000)
Scheme: Grant-Project
Administered By: University of Tasmania
Research Team: Laslett LL; Jones G
Year: 2014

Testing new treatments for back pain: a randomised open label pilot study (2014)$88,721

Description: This project will conduct a randomised open label pilot study on two potential treatments for back pain targeting Modic changes (zoledronic acid or denosumab).
Funding: Tasmanian Community Fund ($88,721)
Scheme: Grant
Administered By: University of Tasmania
Research Team: Laslett LL; Aitken D; Jones G
Year: 2014

Humira for treatment of erosive hand osteoarthritis (2013)$50,000

Funding: Arthritis Australia ($50,000)
Scheme: Fellowship-Research
Administered By: University of Tasmania
Research Team: Laslett LL
Year: 2013

2012 OARSI Young Investigator Scholarship (2012)$6,242

Funding: Osteoarthritis Research Society International ($6,242)
Scheme: Scholarship-Exchange
Administered By: University of Tasmania
Research Team: Laslett LL
Year: 2012

Research Supervision

Dr Laslett has co-supervised one PhD candidate and one Honours student to completion. She currently co-supervise two PhD candidates (Feitong Wu and Zhaohua Zhu) and one Honours student (Sarah Mattap).

She is interested in supervising new PhD candidates or Honours students on aspects of osteoarthritis epidemiology, specifically factors relating to knee pains.

Current

Completed

Current

Degree	Title	Commenced
PhD	Lifestyle and Symptom Management in Multiple Sclerosis	2021
PhD	Understanding the Impact of Pain on People with Multiple Sclerosis	2022
PhD	Sleep in Multiple Sclerosis	2023

Completed

Degree	Title	Completed
PhD	Studies of Bone Microarchitecture in Bone Health in Young and Older Adults and Osteoarthritis Candidate: Canchen Ma	2022
PhD	Utilising Advanced Imaging to Understand Joint Pain and Function Limitations in Older Adults Candidate: Siti Maisarah Binti Mattap	2021
PhD	Clinical Trials of Bone-targeted Therapy for New Indications Candidate: Guoqi Cai	2020
PhD	Association Between Factors in Early Life and Knee Structures in Young Adults Candidate: Tao Meng	2020
PhD	Subchondral Bone Abnormalities in Knee Osteoarthritis Candidate: Zhaohua Zhu	2017
PhD	Strategies to Address the Long-Term Maintenance of Bone Mineral Density in Younger Women Candidate: Feitong Wu	2016