Profiles

Stephen Rattigan

Prof Stephen Rattigan

Stephen Rattigan

Professor
Menzies Institute for Medical Research

Medical Science , Hobart CBD Campuses

+61 3 6226 2671 (phone)

+61 3 6226 7704 (fax)

S.Rattigan@utas.edu.au

Professor Steve Rattigan is a senior member of the Menzies Institute for Medical Research. He leads a group of researchers studying the mechanisms underlying the development of insulin resistance and diabetes. His discoveries have highlighted the important role that insulin has in controlling microvascular blood flow in skeletal muscle and regulating glucose uptake and insulin sensitivity.

Biography

Professor Rattigan did his PhD studies at the University of Western Australia, and has worked previously at CSIRO, Division of Human Nutrition, Adelaide (1982-5), University of Tasmania (1985-1994), University of Virginia, USA (1994-7) and acted as the Deputy Director of The Menzies Institute for Medical Research at the University of Tasmania (2010-2014).

Memberships

Professional practice

Secretary, Australian & New Zealand Microcirculation Society
Australian Physiology Society (Chair Local Organising Committee for Annual Meeting, Hobart 2015)
Australian Diabetes Society
American Diabetes Association
American Physiology Society
The Microcirculatory Society
American Heart Association
American Association for Advancement of Science

Administrative expertise

Deputy Director Menzies Institute for Medical Research (2010-2014)
Chair Laboratory Management Committee (Medical Sciences Building) 2009-2014
Member Project Control Group for Medical Sciences Building Stage 2 Development

Teaching

Teaching expertise

Supervision of Honours and PhD students in Biochemistry and Medical Sciences

Research Appointments

NHMRC-NSFCC Peer Review Working Committee 2015
Global Alliance for Chronic Diseases Peer Review Joint Panel Member 2014
NHMRC Peer Review Panel Member 2012-2013
NHMRC Assigners Academy 2014-5
National Heart Foundation Research Committee Member 2005-2010

Research Invitations

75th Annual Scientific Sessions American Diabetes Association, Boston, June 2015
Mater Medical Research Institute, Brisbane, Australia, Now 2014
RMIT University, Bundoora, Victoria, Australia, April, 2014
Joint Meeting of the Australian Vascular Biology and Australia New Zealand Microcirculation Societies, Barossa Valley, September 2013
National Natural Science Foundation of China- National Health and Medical Research Council Type 2 Diabetes Scientific Symposium, Canberra, Australia, June 2013
Baker IDI seminar series, Melbourne, November 2013
IBEC Satellite Symposium: Molecular regulation of muscle metabolism in exercise and insulin action. Copenhagen, Denmark, June 2012
University of Texas Southwestern Medical Center, Dallas, USA, May 2012
Laval University, Quebec, Canada, April 2012
Inflammation and Chronic Diseases: Arthritis and Beyond, 3rd Australia-China Biomedical Research Conference: Hobart Satellite Meeting, Hobart, Australia, April 2011
ISEAL, Victoria University, December, 2011
9th World Congress for Microcirculation, Paris, France, September, 2010
UK-Physiology, Cardiff, July 2015
Australian Diabetes Society Annual Scientific Meeting, Sydney, Australia, September, 2010

View more on Professor Stephen Rattigan in WARP

Expertise

Type 2 Diabetes
Insulin Resistance
Obesity

Research Themes

Professor Rattigan's research aligns to the University's research theme of Better Health. His research has focussed on the factors that regulate glucose metabolism in skeletal muscle and have led to the important finding that blood flow regulation within muscle is critical to the normal responses to insulin. Impairment of normal blood flow distribution within muscle can lead to insulin resistance and it is his current hypothesis that such defects are the early events associated with obesity and hypertension that contribute to type 2 diabetes.

Collaboration

Prof Rattigan's expertise in regulation of muscle metabolism has led to many requests for collaborations both nationally and internationally. At present he has collaborations with research groups in Victoria University, Melbourne; University of Virginia, USA; University of Maryland; USA, Vrije University and Maastricht University, The Netherlands; University of Copenhagen, Denmark and the Liverpool John Moores University, He also provide sconsultative advice to other groups in the University of Texas, USA and University 'Magna Graecia' of Catanzaro, Italy.

Awards

Career Development Fellowship from National Heart Foundation (2004-7)
NHMRC Senior Research Fellowship 2008-2013)

Current projects

1. Microvascular dysfunction in adult offspring of type 2 diabetics

2. Role of microvascular flowmotion in skeletal muscle glucose metabolism

3. Cardiometabolic benefits of exercise training in type 2 diabetics independent of weight loss

4. Can drinking blueberry tea improve metabolic and vascular health in people with type 2 diabetes?

5. Sodium intake and microvascular-derived insulin resistance6. Role of high fat diets on inflammation

Fields of Research

Endocrinology (320208)
Cardiology (incl. cardiovascular diseases) (320101)
Systems physiology (320803)
Cell metabolism (310103)
Animal physiology - systems (310910)
Biochemistry and cell biology (310199)
Epidemiology (420299)
Medical biochemistry - lipids (320504)
Peripheral nervous system (320906)
Basic pharmacology (321401)
Exercise physiology (420702)
Zoology (310999)
Agricultural biotechnology diagnostics (incl. biosensors) (300101)
Medical biotechnology (320699)
Gene and molecular therapy (320601)
Medical biochemistry - carbohydrates (320502)
Medicinal and biomolecular chemistry (340499)
Medical biochemistry - nucleic acids (320505)
Metabolic medicine (320507)
Health services and systems (420399)
Central nervous system (320903)
Medical physiology (320899)
Protein trafficking (310108)
Clinical pharmacology and therapeutics (321402)
Cell physiology (320801)
Preventative health care (420605)
Animal physiology - biophysics (310908)
Sensory systems (320907)
Nutritional science (321004)

Research Objectives

Clinical health (200199)
Other health (209999)
Expanding knowledge in the environmental sciences (280111)
Human diagnostics (240802)
Human pharmaceutical treatments (240803)
Preventive medicine (200412)
Expanding knowledge in the health sciences (280112)
Disease distribution and transmission (incl. surveillance and response) (200404)
Behaviour and health (200401)
Diagnosis of human diseases and conditions (200101)
Health related to ageing (200502)
Medical instruments (241002)
Nutrition (200410)

Publications

Prof Rattigan has published over 130 publications in peer reviewed journals and his work has been cited over 4,500 times. He is recognized nationally and internationally for my contributions to the vascular action of insulin in muscle and diabetes. His work appears in the major diabetes and physiology journals (Diabetes, Diabetologia, American Journal of Physiology, and Journal of Physiology) and has been the basis for a number of invited reviews (eg, Diabetes, American Journal of Physiology, Microcirculation, Essays in Biochemistry, Exercise and Sports Sciences Reviews). His work has been presented (over 180 abstracts) at numerous national and international meetings.

Total publications

182

Highlighted publications

(5 outputs)

Year	Type	Citation
2004	Journal Article	Vincent MA, Clerk LH, Lindner JR, Klibanov AL, Clark MG, et al., 'Microvascular recruitment is an early insulin effect that regulates skeletal muscle glucose uptake in vivo', Diabetes, 53, (6) pp. 1418-1423. ISSN 0012-1797 (2004) [Refereed Article] DOI: 10.2337/diabetes.53.6.1418 [eCite] [Details] Citations: Scopus - 333Web of Science - 323 Co-authors: Vincent MA; Clark MG Tweet
2004	Journal Article	Zhang L, Vincent MA, Richards SM, Clerk LH, Rattigan S, et al., 'Insulin sensitivity of muscle capillary recruitment in vivo', Diabetes, 53, (2) pp. 447-453. ISSN 0012-1797 (2004) [Refereed Article] DOI: 10.2337/diabetes.53.2.447 [eCite] [Details] Citations: Scopus - 143Web of Science - 135 Co-authors: Zhang L; Vincent MA; Richards SM; Clark MG Tweet
2003	Journal Article	Clark MG, Wallis MG, Barrett EJ, Vincent MA, Richards SM, et al., 'Blood flow and muscle metabolism: a focus on insulin action', American Journal of Physiology: Endocrinology and Metabolism, 284, (2) pp. E241-E258. ISSN 0193-1849 (2003) [Refereed Article] DOI: 10.1152/ajpendo.00408.2002 [eCite] [Details] Citations: Web of Science - 276 Co-authors: Clark MG; Vincent MA; Richards SM Tweet
2002	Journal Article	Vincent MA, Dawson D, Clark ADH, Lindner JR, Rattigan S, et al., 'Skeletal Muscle Microvascular Recruitment by Physiological Hyperinsulinemia Precedes Increases in Total Blood Flow', Diabetes, 51, (1) pp. 42-48. ISSN 0012-1797 (2002) [Refereed Article] DOI: 10.2337/diabetes.51.1.42 [eCite] [Details] Citations: Scopus - 168Web of Science - 155 Co-authors: Clark ADH; Clark MG Tweet
2001	Journal Article	Rattigan S, Wallis MG, Youd JM, Clark MG, 'Exercise Training Improves Insulin-Mediated Capillary Recruitment in Association With Glucose Uptake in Rat Hindlimb', Diabetes, 50, (12) pp. 2659-2665. ISSN 0012-1797 (2001) [Refereed Article] DOI: 10.2337/diabetes.50.12.2659 [eCite] [Details] Citations: Scopus - 50Web of Science - 52 Co-authors: Clark MG Tweet

Journal Article

(113 outputs)

Year	Citation	Altmetrics
2021	Russell RD, Roberts-Thomson KM, Hu D, Greenaway T, Betik AC, et al., 'Impaired postprandial skeletal muscle vascular responses to a mixed meal challenge in normoglycaemic people with a parent with type 2 diabetes', Diabetologia ISSN 0012-186X (2021) [Refereed Article] DOI: 10.1007/s00125-021-05572-7 [eCite] [Details] Citations: Scopus - 8Web of Science - 7 Co-authors: Russell RD; Greenaway T; Sharman JE; Richards SM; Premilovac D; Keske MA Tweet
2020	Keske MA, Barrett EJ, Lindner JR, Richter EA, Liu Z, et al., 'Perfusion controls muscle glucose uptake by altering the rate of glucose dispersion in viv', American Journal of Physiology: Endocrinology and Metabolism, 318, (6) pp. E1022-E1036. ISSN 0193-1849 (2020) [Letter or Note in Journal] DOI: 10.1152/ajpendo.00430.2019 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 Co-authors: Keske MA; Premilovac D; Richards SM Tweet
2019	Roberts-Thomson KM, Betik AC, Premilovac D, Rattigan S, Richards SM, et al., 'Postprandial microvascular blood flow in skeletal muscle: Similarities and disparities to the hyperinsulinaemic-euglycaemic clamp', Clinical and Experimental Pharmacology and Physiology pp. 1-13. ISSN 0305-1870 (2019) [Refereed Article] DOI: 10.1111/1440-1681.13237 [eCite] [Details] Citations: Scopus - 10Web of Science - 8 Co-authors: Premilovac D; Richards SM; Ross RM; Keske MA Tweet
2018	Climie RED, Picone DS, Blackwood S, Keel SE, Qasem A, et al., 'Pulsatile interaction between the macro-vasculature and micro-vasculature: proof-of-concept among patients with type 2 diabetes', European Journal of Applied Physiology, 118, (11) pp. 2455-2463. ISSN 1439-6319 (2018) [Refereed Article] DOI: 10.1007/s00421-018-3972-2 [eCite] [Details] Citations: Scopus - 10Web of Science - 12 Co-authors: Climie RED; Picone DS; Blackwood S; Sharman JE Tweet
2018	Hu D, Remash D, Russell RD, Greenaway T, Rattigan S, et al., 'Impairments in adipose tissue microcirculation in Type 2 diabetes mellitus assessed by real-time contrast-enhanced ultrasound', Circulation: Cardiovascular Imaging, 11, (4) Article e007074. ISSN 1942-0080 (2018) [Refereed Article] DOI: 10.1161/CIRCIMAGING.117.007074 [eCite] [Details] Citations: Scopus - 15Web of Science - 16 Co-authors: Remash D; Russell RD; Greenaway T; Squibb KA; Jones G; Premilovac D; Richards SM; Keske MA Tweet
2018	Hu D, Russell RD, Remash D, Greenaway T, Rattigan S, et al., 'Are the metabolic benefits of resistance training in type 2 diabetes linked to improvements in adipose tissue microvascular blood flow?', American Journal of Physiology: Endocrinology and Metabolism, 315, (6) pp. E1242-E1250. ISSN 0193-1849 (2018) [Refereed Article] DOI: 10.1152/ajpendo.00234.2018 [eCite] [Details] Citations: Scopus - 3Web of Science - 3 Co-authors: Russell RD; Remash D; Greenaway T; Squibb KA; Jones G; Ross RM; Premilovac D; Richards SM; Keske MA Tweet
2018	Premilovac D, Attrill EH, Rattigan S, Richards SM, Kim J, et al., 'Acute, local infusion of angiotensin II impairs microvascular and metabolic insulin sensitivity in skeletal muscle', Cardiovascular Research pp. 1-12. ISSN 0008-6363 (2018) [Refereed Article] DOI: 10.1093/cvr/cvy225 [eCite] [Details] Citations: Scopus - 9Web of Science - 9 Co-authors: Premilovac D; Attrill EH; Richards SM; Keske MA Tweet
2018	Russell RD, Hu D, Greenaway T, Sharman JE, Rattigan S, et al., 'Oral glucose challenge impairs skeletal muscle microvascular blood flow in healthy people', American Journal of Physiology - Endocrinology and Metabolism, 315, (2) pp. E307-E315. ISSN 0193-1849 (2018) [Refereed Article] DOI: 10.1152/ajpendo.00448.2017 [eCite] [Details] Citations: Scopus - 23Web of Science - 24 Co-authors: Russell RD; Greenaway T; Sharman JE; Richards SM; Keske MA Tweet
2017	Blackwood SJ, Dwyer RM, Bradley EA, Keske MA, Richards SM, et al., 'Determination of skeletal muscle microvascular flowmotion with contrast-enhanced ultrasound', Ultrasound in Medicine and Biology, 43, (9) pp. 2013-2023. ISSN 0301-5629 (2017) [Refereed Article] DOI: 10.1016/j.ultrasmedbio.2017.05.012 [eCite] [Details] Citations: Scopus - 7Web of Science - 6 Co-authors: Blackwood SJ; Dwyer RM; Bradley EA; Keske MA; Richards SM Tweet
2017	Keske MA, Dwyer RM, Russell RD, Blackwood SJ, Brown AA, et al., 'Regulation of microvascular flow and metabolism: An overview', Clinical and Experimental Pharmacology and Physiology, 44, (1) pp. 143-149. ISSN 0305-1870 (2017) [Refereed Article] DOI: 10.1111/1440-1681.12688 [eCite] [Details] Citations: Scopus - 20Web of Science - 19 Co-authors: Keske MA; Dwyer RM; Russell RD; Blackwood SJ; Brown AA; Premilovac D; Richards SM Tweet
2017	Ng HLH, Premilovac D, Rattigan S, Richards SM, Muniyappa R, et al., 'Acute vascular and metabolic actions of the green tea polyphenol epigallocatechin 3-gallate in rat skeletal muscle', Journal of Nutritional Biochemistry, 40 pp. 23-31. ISSN 0955-2863 (2017) [Refereed Article] DOI: 10.1016/j.jnutbio.2016.10.005 [eCite] [Details] Citations: Scopus - 9Web of Science - 9 Co-authors: Ng HLH; Premilovac D; Richards SM; Keske MA Tweet
2017	Russell RD, Hu D, Greenaway T, Blackwood SJ, Dwyer RM, et al., 'Skeletal muscle microvascular-linked improvements in glycemic control from resistance training in individuals with Type 2 Diabetes', Diabetes Care, 40, (9) pp. 1256-1263. ISSN 0149-5992 (2017) [Refereed Article] DOI: 10.2337/dc16-2750 [eCite] [Details] Citations: Scopus - 50Web of Science - 42 Co-authors: Russell RD; Greenaway T; Blackwood SJ; Dwyer RM; Sharman JE; Jones G; Squibb KA; Brown AA; Otahal P; Al-Aubaidy H; Premilovac D; Hitchins S; Richards SM; Keske MA Tweet
2017	Sjoberg KA, Frosig C, Kjobsted R, Sylow L, Kleinert M, et al., 'Exercise increases human skeletal muscle insulin sensitivity via coordinated increases in microvascular perfusion and molecular signaling', Diabetes, 66, (6) pp. 1501-1510. ISSN 0012-1797 (2017) [Refereed Article] DOI: 10.2337/db16-1327 [eCite] [Details] Citations: Scopus - 107Web of Science - 92 Tweet
2017	Zhang X, Hiam D, Hong YH, Zulli A, Hayes A, et al., 'Nitric oxide is required for the insulin sensitizing effects of contraction in mouse skeletal muscle', Journal of Physiology, 595, (24) pp. 7427-7439. ISSN 0022-3751 (2017) [Refereed Article] DOI: 10.1113/JP275133 [eCite] [Details] Citations: Scopus - 6Web of Science - 5 Tweet
2016	Keske MA, Premilovac D, Bradley EA, Dwyer RM, Richards SM, et al., 'Muscle microvascular blood flow responses in insulin resistance and ageing', The Journal of Physiology, 594, (8) pp. 2223-2231. ISSN 1469-7793 (2016) [Refereed Article] DOI: 10.1113/jphysiol.2014.283549 [eCite] [Details] Citations: Scopus - 45Web of Science - 47 Co-authors: Keske MA; Premilovac D; Bradley EA; Dwyer RM; Richards SM Tweet
2015	Bradley EA, Zhang L, Genders AJ, Richards SM, Rattigan S, et al., 'Enhancement of insulin-mediated rat muscle glucose uptake and microvascular perfusion by 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside', Cardiovascular Diabetology, 14, (1) Article 91. ISSN 1475-2840 (2015) [Refereed Article] DOI: 10.1186/s12933-015-0251-y [eCite] [Details] Citations: Scopus - 6Web of Science - 6 Co-authors: Bradley EA; Richards SM; Keske MA Tweet
2015	Hong YH, Betik AC, Premilovac D, Dwyer RM, Keske MA, et al., 'No effect of NOS inhibition on skeletal muscle glucose uptake during in situ hindlimb contraction in healthy and diabetic Sprague-Dawley rats', American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 308, (10) pp. R862-R871. ISSN 0363-6119 (2015) [Refereed Article] DOI: 10.1152/ajpregu.00412.2014 [eCite] [Details] Citations: Scopus - 10Web of Science - 10 Co-authors: Premilovac D; Dwyer RM; Keske MA Tweet
2015	Hong YH, Frugier T, Zhang X, Murphy RM, Lynch GS, et al., 'Glucose uptake during contraction in isolated skeletal muscles from neuronal nitric oxide synthase μ knockout mice', Journal of Applied Physiology, 118, (9) pp. 1113-1121. ISSN 8750-7587 (2015) [Refereed Article] DOI: 10.1152/japplphysiol.00056.2015 [eCite] [Details] Citations: Scopus - 12Web of Science - 12 Tweet
2015	Keske MA, Ng HLH, Premilovac D, Rattigan S, Kim J, et al., 'Vascular and metabolic actions of the green tea polyphenol epigallocatechin gallate', Current Medicinal Chemistry, 22, (1) pp. 59-69. ISSN 0929-8673 (2015) [Refereed Article] DOI: 10.2174/0929867321666141012174553 [eCite] [Details] Citations: Scopus - 63Web of Science - 65 Co-authors: Keske MA; Ng HLH; Premilovac D Tweet
2015	Sjoberg KA, Rattigan S, Jeppesen JF, Lundsgaard A-M, Holst JJ, et al., 'Differential effects of glucagon-like peptide-1 on microvascular recruitment and glucose metabolism in short- and long-term insulin resistance', Journal of Physiology, 593, (9) pp. 2185-2198. ISSN 0022-3751 (2015) [Refereed Article] DOI: 10.1113/JP270129 [eCite] [Details] Citations: Scopus - 22Web of Science - 20 Tweet
2014	Barrett EJ, Keske MA, Rattigan S, Eringa EC, 'Rebuttal from Eugene J. Barrett, Michelle A. Keske, Stephen Rattigan and Etto C. Eringa', The Journal of physiology, 592, (23) pp. 5137-5138. ISSN 0022-3751 (2014) [Contribution to Refereed Journal] DOI: 10.1113/jphysiol.2014.284604 [eCite] [Details] Citations: Scopus - 1Web of Science - 1 Co-authors: Keske MA Tweet
2014	Barrett EJ, Keske MA, Rattigan S, Eringa EC, 'CrossTalk proposal: De novo capillary recruitment in healthy muscle is necessary', Journal of Physiology, 592, (23) pp. 5129-5131. ISSN 0022-3751 (2014) [Refereed Article] DOI: 10.1113/jphysiol.2014.282137 [eCite] [Details] Citations: Scopus - 8Web of Science - 9 Co-authors: Keske MA Tweet
2014	Premilovac D, Richards SM, Rattigan S, Keske MA, 'A vascular mechanism for high-sodium-induced insulin resistance in rats', Diabetologia: Clinical and Experimental Diabetes and Metabolism, 57, (12) pp. 2586-2595. ISSN 0012-186X (2014) [Refereed Article] DOI: 10.1007/s00125-014-3373-y [eCite] [Details] Citations: Scopus - 24Web of Science - 24 Co-authors: Premilovac D; Richards SM; Keske MA Tweet
2014	Sjoberg KA, Holst JJ, Rattigan S, Richter EA, Kiens B, 'GLP-1 increases microvascular recruitment but not glucose uptake in human and rat skeletal muscle', American Journal of Physiology: Endocrinology and Metabolism, 306, (4) pp. E355-E362. ISSN 0193-1849 (2014) [Refereed Article] DOI: 10.1152/ajpendo.00283.2013 [eCite] [Details] Citations: Scopus - 44Web of Science - 46 Tweet
2013	Bradley EA, Richards SM, Keske MA, Rattigan S, 'Local NOS inhibition impairs vascular and metabolic actions of insulin in rat hindleg muscle in vivo', American Journal of Physiology: Endocrinology and Metabolism, 305, (6) pp. E745-E750. ISSN 0193-1849 (2013) [Refereed Article] DOI: 10.1152/ajpendo.00289.2013 [eCite] [Details] Citations: Scopus - 29Web of Science - 28 Co-authors: Bradley EA; Richards SM; Keske MA Tweet
2013	Jacobson GA, Yee KC, Premilovac D, Rattigan S, 'Enantioselective disposition of (R/S)-albuterol in skeletal and cardiac muscle', Drug Testing and Analysis, 6, (6) pp. 563-567. ISSN 1942-7603 (2013) [Refereed Article] DOI: 10.1002/dta.1575 [eCite] [Details] Citations: Scopus - 16Web of Science - 15 Co-authors: Jacobson GA; Yee KC; Premilovac D Tweet
2013	Keith LJ, Rattigan S, Keske MA, Jose M, Sharman JE, 'Exercise aortic stiffness: Reproducibility and relation to end-organ damage in men', Journal of Human Hypertension, 27, (8) pp. 516-522. ISSN 0950-9240 (2013) [Refereed Article] DOI: 10.1038/jhh.2013.5 [eCite] [Details] Citations: Scopus - 12Web of Science - 12 Co-authors: Keith LJ; Keske MA; Jose M; Sharman JE Tweet
2013	Premilovac D, Bradley EA, Ng HLH, Richards SM, Rattigan S, et al., 'Muscle insulin resistance resulting from impaired microvascular insulin sensitivity in Sprague Dawley rats', Cardiovascular Research, 98, (1) pp. 28-36. ISSN 0008-6363 (2013) [Refereed Article] DOI: 10.1093/cvr/cvt015 [eCite] [Details] Citations: Scopus - 33Web of Science - 31 Co-authors: Premilovac D; Bradley EA; Ng HLH; Richards SM; Keske MA Tweet
2013	Premilovac D, Roberts-Thompson KM, Ng HLH, Bradley EA, Richards SM, et al., 'Blueberry tea enhances insulin sensitivity by augmenting insulin-mediated metabolic and microvascular responses in skeletal muscle of high fat fed rats', International Journal of Diabetology & Vascular Disease Research, 1, (8) pp. 1-10. ISSN 2328-353X (2013) [Non Refereed Article] [eCite] [Details] Co-authors: Premilovac D; Ng HLH; Bradley EA; Richards SM; Keske MA Tweet
2013	Rattigan S, Richards SM, Keske MA, 'Microvascular contributions to insulin resistance', Diabetes, 62, (2) pp. 343-345. ISSN 0012-1797 (2013) [Contribution to Refereed Journal] DOI: 10.2337/db12-1193 [eCite] [Details] Citations: Scopus - 11Web of Science - 11 Co-authors: Richards SM; Keske MA Tweet
2012	Barrett EJ, Rattigan S, 'Muscle perfusion: its measurement and role in metabolic regulation', Diabetes, 61, (11) pp. 2661-2668. ISSN 0012-1797 (2012) [Refereed Article] DOI: 10.2337/db12-0271 [eCite] [Details] Citations: Scopus - 37Web of Science - 37 Tweet
2012	McConell GK, Rattigan S, Lee-Young RS, Wadley GD, Merry TL, 'Skeletal muscle nitric oxide signaling and exercise: a focus on glucose metabolism', American Journal of Physiology: Endocrinology and Metabolism, 303, (3) pp. E301-E307. ISSN 0193-1849 (2012) [Refereed Article] DOI: 10.1152/ajpendo.00667.2011 [eCite] [Details] Citations: Scopus - 64Web of Science - 62 Tweet
2012	Meijer RI, De Boer MP, Groen MR, Eringa EC, Rattigan S, et al., 'Insulin-induced microvascular recruitment in skin and muscle are related and both are associated with whole-body glucose uptake', Microcirculation, 19, (6) pp. 494-500. ISSN 1073-9688 (2012) [Refereed Article] DOI: 10.1111/j.1549-8719.2012.00174.x [eCite] [Details] Citations: Scopus - 62Web of Science - 62 Tweet
2012	St-Pierre P, Keith LJ, Richards SM, Rattigan S, Keske MA, 'Microvascular blood flow responses to muscle contraction are not altered by high-fat feeding in rats', Diabetes, Obesity and Metabolism, 14, (8) pp. 753-761. ISSN 1462-8902 (2012) [Refereed Article] DOI: 10.1111/j.1463-1326.2012.01598.x [eCite] [Details] Citations: Scopus - 15Web of Science - 16 Co-authors: Keith LJ; Richards SM; Keske MA Tweet
2011	Bussey CT, Kolka CM, Rattigan S, Richards SM, 'Adiponectin opposes endothelin-1-mediated vasoconstriction in the perfused rat hindlimb', American Journal of Physiology: Heart and Circulatory Physiology, 301, (1) pp. H79-H86. ISSN 0363-6135 (2011) [Refereed Article] DOI: 10.1152/ajpheart.00864.2010 [eCite] [Details] Citations: Scopus - 19Web of Science - 21 Co-authors: Bussey CT; Kolka CM; Richards SM Tweet
2011	Genders AJ, Bradley EA, Rattigan S, Richards SM, 'cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle', American Journal of Physiology: Endocrinology and Metabolism, 301, (2) pp. E342-E350. ISSN 0193-1849 (2011) [Refereed Article] DOI: 10.1152/ajpendo.00691.2010 [eCite] [Details] Citations: Scopus - 19Web of Science - 18 Co-authors: Genders AJ; Bradley EA; Richards SM Tweet
2011	Sjoberg KA, Rattigan S, Hiscock N, Richter EA, Kiens B, 'A new method to study changes in microvascular blood volume in muscle and adipose tissue: real-time imaging in humans and rat', American Journal of Physiology: Heart and Circulatory Physiology, 301, (2) pp. H450-H458. ISSN 0363-6135 (2011) [Refereed Article] DOI: 10.1152/ajpheart.01174.2010 [eCite] [Details] Citations: Scopus - 64Web of Science - 66 Tweet
2010	Bradley EA, Eringa EC, Stehouwer CDA, Korstjens I, van Nieuw Amerongen GP, et al., 'Activation of AMP-Activated Protein Kinase by 5-Aminoimidazole-4-Carboxamide-1-β-D-Ribofuranoside in the Muscle Microcirculation Increases Nitric Oxide Synthesis and Microvascular Perfusion', Arteriosclerosis, Thrombosis, and Vascular Biology, 30, (6) pp. 1137-1142. ISSN 1079-5642 (2010) [Refereed Article] DOI: 10.1161/ATVBAHA.110.204404 [eCite] [Details] Citations: Scopus - 56Web of Science - 56 Co-authors: Bradley EA; Clark MG Tweet
2010	Bradley EA, Willson KJ, Choi-Lundberg D, Clark MG, Rattigan S, 'Effects of central administration of insulin or L-NMMA on rat skeletal muscle microvascular perfusion', Diabetes Obesity & Metabolism, 12, (10) pp. 900-908. ISSN 1462-8902 (2010) [Refereed Article] DOI: 10.1111/j.1463-1326.2010.01253.x [eCite] [Details] Citations: Scopus - 7Web of Science - 6 Co-authors: Bradley EA; Willson KJ; Choi-Lundberg D; Clark MG Tweet
2010	Merry TL, Dwyer RM, Bradley EA, Rattigan S, McConell GK, 'Local hindlimb antioxidant infusion does not affect muscle glucose uptake during in situ contractions in rat', Journal of Applied Physiology, 108, (5) pp. 1275-1283. ISSN 8750-7587 (2010) [Refereed Article] DOI: 10.1152/japplphysiol.01335.2009 [eCite] [Details] Citations: Scopus - 18Web of Science - 17 Co-authors: Dwyer RM; Bradley EA Tweet
2010	Merry TL, Wadley GD, Stathis CG, Garnham AP, Rattigan S, et al., 'N Acetylcysteine infusion does not affect glucose disposal during prolonged moderate-intensity exercise in humans', Journal of Physiology, 588, (9) pp. 1623-1634. ISSN 0022-3751 (2010) [Refereed Article] DOI: 10.1113/jphysiol.2009.184333 [eCite] [Details] Citations: Scopus - 36Web of Science - 33 Tweet
2010	St Pierre P, Genders AJ, Keske MA, Richards SM, Rattigan S, 'Loss of insulin-mediated microvascular perfusion in skeletal muscle is associated with the development of insulin resistance ', Diabetes Obesity & Metabolism, 12, (9) pp. 798-805. ISSN 1462-8902 (2010) [Refereed Article] DOI: 10.1111/j.1463-1326.2010.01235.x [eCite] [Details] Citations: Scopus - 32Web of Science - 30 Co-authors: Genders AJ; Keske MA; Richards SM Tweet
2009	Newman JMB, Dwyer RM, St Pierre P, Richards SM, Clark MG, et al., 'Decreased microvascular vasomotion and myogenic response in rat skeletal muscle in association with acute insulin resistance', Journal of Physiology, 587, (11) pp. 2579-2588. ISSN 0022-3751 (2009) [Refereed Article] DOI: 10.1113/jphysiol.2009.169011 [eCite] [Details] Citations: Scopus - 65Web of Science - 56 Co-authors: Newman JMB; Dwyer RM; Richards SM; Clark MG Tweet
2009	Yuen DYC, Dwyer RM, Matthews VB, Zhang L, Drew BG, et al., 'Interleukin-6 attenuates insulin-mediated increases in endothelial cell signaling but augments skeletal muscle insulin action via differential effects on tumor necrosis factor-a expression', Diabetes, 58, (May) pp. 1086-1095. ISSN 0012-1797 (2009) [Refereed Article] DOI: 10.2337/db08-0775 [eCite] [Details] Citations: Scopus - 42Web of Science - 39 Co-authors: Dwyer RM; Zhang L; Clark MG Tweet
2008	Clark MG, Rattigan S, Barrett EJ, Keske MAV, 'Point: Counterpoint: There is/is not capillary recruitment in active skeletal muscle during exercise', Journal of Appliedy Physiology, 104, (3) pp. 889-891. ISSN 8750-7587 (2008) [Contribution to Refereed Journal] DOI: 10.1152/japplphysiol.00779.2007 [eCite] [Details] Citations: Scopus - 48Web of Science - 47 Co-authors: Clark MG; Keske MAV Tweet
2008	Clark MG, Rattigan S, Barrett EJ, Keske MAV, 'Last word on Point:Counterpoint: There is/is not capillary recruitment in active skeletal muscle during exercise', Journal of Applied Physiology, 104, (3) pp. 900. ISSN 8750-7587 (2008) [Contribution to Refereed Journal] DOI: 10.1152/japplphysiol.01318.2007 [eCite] [Details] Citations: Scopus - 7Web of Science - 5 Co-authors: Clark MG; Keske MAV Tweet
2008	Ross RM, Downey KA, Newman JMB, Richards SM, Clark MG, et al., 'Contrast-enhanced ultrasound measurement of microvascular perfusion relevant to nutrient and hormone delivery in skeletal muscle: A model study in vitro', Microvascular Research, 75, (3) pp. 323-329. ISSN 0026-2862 (2008) [Refereed Article] DOI: 10.1016/j.mvr.2007.11.002 [eCite] [Details] Citations: Scopus - 12Web of Science - 11 Co-authors: Ross RM; Downey KA; Newman JMB; Richards SM; Clark MG Tweet
2007	Bradley EA, Clark MG, Rattigan S, 'Acute effects of wortmannin on insulin's hemodynamic and metabolic actions in vivo', American Journal of Physiology: Endocrinology and Metabolism, 292, (3) pp. E779-E787. ISSN 0193-1849 (2007) [Refereed Article] DOI: 10.1152/ajpendo.00407.2006 [eCite] [Details] Citations: Scopus - 13Web of Science - 10 Co-authors: Bradley EA; Clark MG Tweet
2007	Clark MG, Rattigan S, Barrett EJ, Vincent MA, 'There is / is not capillary recruitment in active skeletal muscle during exercise', Journal of Applied Physiology, 104, (3) pp. 889-891. ISSN 8750-7587 (2007) [Non Refereed Article] DOI: 10.1152/japplphysiol.00779.2007 [eCite] [Details] Citations: Scopus - 48Web of Science - 47 Co-authors: Clark MG Tweet
2007	Kolka CM, Rattigan S, Richards SM, Clark MG, 'Potential for endothelin-1-mediated impairment of contractile activity in hypertension', Clinical and Experimental Physiology and Pharmacology, 34, (3) pp. 217-222. ISSN 0305-1870 (2007) [Refereed Article] DOI: 10.1111/j.1440-1681.2007.04575.x [eCite] [Details] Citations: Scopus - 1Web of Science - 5 Co-authors: Kolka CM; Richards SM; Clark MG Tweet
2007	Newman JMB, Ross RM, Richards SM, Clark MG, Rattigan S, 'Insulin and contraction increase nutritive blood flow in rat muscle in vivo: determined by microdialysis of L-[14C]glucose', Journal of Physiology, 585, (1) pp. 217-229. ISSN 0022-3751 (2007) [Refereed Article] DOI: 10.1113/jphysiol.2007.138818 [eCite] [Details] Citations: Scopus - 15Web of Science - 14 Co-authors: Newman JMB; Ross RM; Richards SM; Clark MG Tweet
2007	Rattigan S, Bussey CT, Ross RM, Richards SM, 'Obesity, Insulin Resistance, and Capillary Recruitment', Microcirculation, 14, (4-5) pp. 299-309. ISSN 1073-9688 (2007) [Refereed Article] DOI: 10.1080/10739680701282796 [eCite] [Details] Citations: Scopus - 26Web of Science - 24 Co-authors: Bussey CT; Ross RM; Richards SM Tweet
2007	Ross RM, Kolka CM, Rattigan S, Clark MG, 'Acute blockade by endothelin-1 of haemodynamic insulin action in rats', Diabetologia, 50, (2) pp. 443-451. ISSN 0012-186X (2007) [Refereed Article] DOI: 10.1007/s00125-006-0525-8 [eCite] [Details] Citations: Scopus - 30Web of Science - 27 Co-authors: Ross RM; Kolka CM; Clark MG Tweet
2007	Ross RM, Wadley GD, Clark MG, Rattigan S, McConell GK, 'Local nitric oxide synthase inhibition reduces skeletal muscle glucose uptake but not capillary blood flow during in situ muscle contraction in rats', Diabetes, 56, (12) pp. 2885-2892. ISSN 0012-1797 (2007) [Refereed Article] DOI: 10.2337/db07-0745 [eCite] [Details] Citations: Scopus - 59Web of Science - 60 Co-authors: Ross RM; Clark MG Tweet
2007	Vollus GC, Bradley EA, Roberts NK, Newman JMB, Richards SM, et al., 'Graded occlusion of perfused rat muscle vasculature decreases insulin action', Clinical Science, 112, (8) pp. 457-466. ISSN 0143-5221 (2007) [Refereed Article] DOI: 10.1042/CS20060311 [eCite] [Details] Citations: Scopus - 16Web of Science - 13 Co-authors: Vollus GC; Bradley EA; Roberts NK; Newman JMB; Richards SM; Clark MG Tweet
2006	Clark MG, Rattigan S, Barrett EJ, 'Nutritive blood flow as an essential element supporting muscle anabolism', Current Opinion in Clinical Nutrition and Metabolic Care, 9, (3) pp. 185-189. ISSN 1363-1950 (2006) [Refereed Article] DOI: 10.1097/01.mco.0000222097.90890.c2 [eCite] [Details] Citations: Scopus - 76Web of Science - 29 Co-authors: Clark MG Tweet
2006	Mahajan H, Kolka CM, Newman JMB, Rattigan S, Richards SM, et al., 'Vascular and metabolic effects of methacholine in relation to insulin action in muscle', Diabetologia, 49, (4) pp. 713-723. ISSN 0012-186X (2006) [Refereed Article] DOI: 10.1007/s00125-005-0110-6 [eCite] [Details] Citations: Scopus - 4Web of Science - 3 Co-authors: Mahajan H; Kolka CM; Newman JMB; Richards SM; Clark MG Tweet
2006	Rattigan S, Bradley EA, Richards SM, Clark MG, 'Muscle metabolism and control of capillary blood flow: insulin and exercise', Essays in Biochemistry, 42, (1) pp. 133-144. ISSN 0071-1365 (2006) [Refereed Article] DOI: 10.1042/bse0420133 [eCite] [Details] Citations: Scopus - 9Web of Science - 8 Co-authors: Bradley EA; Richards SM; Clark MG Tweet
2006	Rattigan S, Zhang L, Mahajan H, Kolka CM, Richards SM, et al., 'Factors influencing the hemodynamic and metabolic effects of insulin in muscle', Current Diabetes Reviews, 2, (1) pp. 61-70. ISSN 1573-3998 (2006) [Refereed Article] DOI: 10.2174/157339906775473653 [eCite] [Details] Citations: Scopus - 8 Co-authors: Zhang L; Mahajan H; Kolka CM; Richards SM; Clark MG Tweet
2005	Kolka CM, Rattigan S, Richards SM, Barrett EJ EJ, Clark MG, 'Endothelial Na+ -D-glucose cotransporter: No Role in Insulin-mediated Glucose Uptake ', Hormone and Metabolic Research, 37, (11) pp. 657-661. ISSN 0018-5043 (2005) [Refereed Article] DOI: 10.1055/s-2005-870574 [eCite] [Details] Citations: Scopus - 2Web of Science - 2 Co-authors: Kolka CM; Richards SM; Clark MG Tweet
2005	Kolka CM, Rattigan S, Richards SM, Clark MG, 'Metabolic and vascular actions of endothelin-1 are inhibited by insulin-mediated vasodilation in perfused rat hindlimb muscle', British Journal of Pharmacology, 145, (7) pp. 992-1000. ISSN 0007-1188 (2005) [Refereed Article] DOI: 10.1038/sj.bjp.0706263 [eCite] [Details] Citations: Scopus - 16Web of Science - 17 Co-authors: Kolka CM; Richards SM; Clark MG Tweet
2005	Rattigan S, Wheatley C, Richards SM, Barrett EJ, Clark MG, 'Exercise and insulin-mediated capillary recruitment in muscle', Exercise and Sport Sciences Reviews, 33, (1) pp. 43-48. ISSN 0091-6331 (2005) [Refereed Article] PMID: 15640720 [eCite] [Details] Citations: Scopus - 27Web of Science - 30 Co-authors: Richards SM Tweet
2005	Roberts JL, Newman JMB, Warner RC, Rattigan S, Clark MG, 'Axially symmetric semi-infinite domain models of microdialysis and their application to the determination of nutritive flow in rat muscle', Journal of Physiology, 563, (1) pp. 213-228. ISSN 0022-3751 (2005) [Refereed Article] DOI: 10.1113/jphysiol.2003.056531 [eCite] [Details] Citations: Scopus - 4Web of Science - 4 Co-authors: Roberts JL; Newman JMB; Warner RC; Clark MG Tweet
2005	Vincent MA, Clerk LH, Rattigan S, Clark MG, Barrett EJ, 'Active role for the vasculature in the delivery of insulin to skeletal muscle', Clinical and Experimental Pharmacology and Physiology, 32, (4) pp. 302-307. ISSN 0305-1870 (2005) [Refereed Article] DOI: 10.1111/j.1440-1681.2005.04188.x [eCite] [Details] Citations: Scopus - 57Web of Science - 54 Co-authors: Vincent MA Tweet
2005	Wallis MG, Smith ME, Kolka CM, Zhang L, Richards SM, et al., 'Acute glucosamine-induced insulin resistance in muscle in vivo is associated with impaired capillary recruitment', Diabetologia, 48, (10) pp. 2131-2139. ISSN 0012-186X (2005) [Refereed Article] DOI: 10.1007/s00125-005-1887-z [eCite] [Details] Citations: Scopus - 31Web of Science - 27 Co-authors: Smith ME; Kolka CM; Zhang L; Richards SM; Clark MG Tweet
2005	Zhang L, Newman JMB, Richards SM, Rattigan S, Clark MG, 'Microvascular flow routes in muscle controlled by vasoconstrictors', Microvascular Research, 70, (1) pp. 7-16. ISSN 0026-2862 (2005) [Refereed Article] DOI: 10.1016/j.mvr.2005.06.001 [eCite] [Details] Citations: Scopus - 13Web of Science - 11 Co-authors: Zhang L; Newman JMB; Richards SM; Clark MG Tweet
2004	Clerk LC, Vincent MA, Lindner J, Clark MG, Rattigan S, et al., 'The vasodilatory actions of insulin on resistance and terminal arterioles and their impact on muscle glucose uptake', Diabetes/Metabolism Reseach and Reviews, 20, (1) pp. 3-12. ISSN 1520-7552 (2004) [Refereed Article] DOI: 10.1002/dmrr.414 [eCite] [Details] Citations: Scopus - 89Web of Science - 81 Co-authors: Vincent MA; Clark MG Tweet
2004	Mahajan H, Richards SM, Rattigan S, Clark MG, 'Local methacholine but not bradykinin potentiates insulin-mediated capillary recruitment and glucose uptake in muscle in vivo', Diabetologia, 47, (12) pp. 2226-2234. ISSN 0012-186X (2004) [Refereed Article] DOI: 10.1007/s00125-004-1580-7 [eCite] [Details] Citations: Scopus - 20Web of Science - 17 Co-authors: Mahajan H; Richards SM; Clark MG Tweet
2004	Vincent MA, Clerk LH, Lindner JR, Klibanov AL, Clark MG, et al., 'Microvascular recruitment is an early insulin effect that regulates skeletal muscle glucose uptake in vivo', Diabetes, 53, (6) pp. 1418-1423. ISSN 0012-1797 (2004) [Refereed Article] DOI: 10.2337/diabetes.53.6.1418 [eCite] [Details] Citations: Scopus - 333Web of Science - 323 Co-authors: Vincent MA; Clark MG Tweet
2004	Wheatley CM, Rattigan S, Richards SM, Barrett EJ, Clark MG, 'Skeletal muscle contraction stimulates capillary recruitment and glucose uptake in insulin resistant obese Zucker rats', American Journal of Physiology - Endocrinology and Metabolism, 287, (4) pp. E804-E807. ISSN 0193-1849 (2004) [Refereed Article] DOI: 10.1152/ajpendo.00077.2004 [eCite] [Details] Citations: Scopus - 51Web of Science - 53 Co-authors: Richards SM; Clark MG Tweet
2004	Zhang L, Vincent MA, Richards SM, Clerk LH, Rattigan S, et al., 'Insulin sensitivity of muscle capillary recruitment in vivo', Diabetes, 53, (2) pp. 447-453. ISSN 0012-1797 (2004) [Refereed Article] DOI: 10.2337/diabetes.53.2.447 [eCite] [Details] Citations: Scopus - 143Web of Science - 135 Co-authors: Zhang L; Vincent MA; Richards SM; Clark MG Tweet
2003	Clark MG, Wallis MG, Barrett EJ, Vincent MA, Richards SM, et al., 'Blood flow and muscle metabolism: a focus on insulin action', American Journal of Physiology: Endocrinology and Metabolism, 284, (2) pp. E241-E258. ISSN 0193-1849 (2003) [Refereed Article] DOI: 10.1152/ajpendo.00408.2002 [eCite] [Details] Citations: Web of Science - 276 Co-authors: Clark MG; Vincent MA; Richards SM Tweet
2003	Clerk LH, Smith ME, Rattigan S, Clark MG, 'Nonnutritive flow impairs uptake of fatty acids by white muscles of the perfused rat hindlimb', American Journal of Physiology: Endocrinology and Metabolism, 284, (3 47-3) pp. E611-E617. ISSN 0193-1849 (2003) [Refereed Article] DOI: 10.1152/ajpendo.00153.2002 [eCite] [Details] Citations: Scopus - 8Web of Science - 7 Co-authors: Smith ME; Clark MG Tweet
2003	Mahajan H, Richards SM, Rattigan S, Clark MG, 'T-1032, a cyclic GMP phosphodiesterase-5 inhibitor, acutely blocks physiologic insulin-mediated muscle haemodynamic effects and glucose uptake in vivo', British Journal of Pharmacology, 140, (7) pp. 1283-1291. ISSN 0007-1188 (2003) [Refereed Article] DOI: 10.1038/sj.bjp.0705548 [eCite] [Details] Citations: Scopus - 8Web of Science - 7 Co-authors: Mahajan H; Richards SM; Clark MG Tweet
2003	Rattigan S, Barrett EJ, Clark MG, 'Insulin-mediated Capillary Recruitment in Skeletal Muscle: Is This a Mediator of Insulin Action on Glucose Metabolism?', Current Diabetes Reports, 3, (3) pp. 195-200. ISSN 1534-4827 (2003) [Non Refereed Article] DOI: 10.1007/s11892-003-0063-4 [eCite] [Details] Citations: Scopus - 13 Co-authors: Clark MG Tweet
2003	Vincent MA, Barrett EJ, Lindner JR, Clark MG, Rattigan S, 'Inhibiting NOS blocks microvascular recruitment and blunts muscle glucose uptake in response to insulin', American Journal of Physiology: Endocrinology and Metabolism, 285, (1 48-1) pp. E123-E129. ISSN 0193-1849 (2003) [Refereed Article] DOI: 10.1152/ajpendo.00021.2003 [eCite] [Details] Citations: Scopus - 258Web of Science - 249 Co-authors: Vincent MA; Clark MG Tweet
2003	Zhang L, Wheatley CM, Richards SM, Barrett EJ, Clark MG, et al., 'TNFalpha acutely inhibits vascular effects of physiological but not high insulin or contraction', American Journal of Physiology: Endocrinology and Metabolism, 285, (3 ) pp. E654-E660. ISSN 0193-1849 (2003) [Refereed Article] DOI: 10.1152/ajpendo.00119.2003 [eCite] [Details] Citations: Scopus - 51Web of Science - 50 Co-authors: Zhang L; Richards SM; Clark MG Tweet
2002	Clark MG, Barrett EJ, Wallis MG, Vincent MA, Rattigan S, 'The Microvasculature in Insulin Resistance and Type 2 Diabetes', Seminars in Vascular Medicine, 2, (1) pp. 21-31. ISSN 1528-9648 (2002) [Refereed Article] DOI: 10.1055/s-2002-23506 [eCite] [Details] Citations: Scopus - 37 Co-authors: Clark MG Tweet
2002	Clerk LH, Rattigan S, Clark MG, 'Lipid Infusion Impairs Physiologic Insulin-Mediated Capillary Recruitment and Muscle Glucose Uptake In Vivo', Diabetes, 51, (4) pp. 1138-1145. ISSN 0012-1797 (2002) [Refereed Article] DOI: 10.2337/diabetes.51.4.1138 [eCite] [Details] Citations: Scopus - 138Web of Science - 127 Co-authors: Clark MG Tweet
2002	DiMaria CA, Rattigan S, Clark MG, 'Vasoconstrictor-mediated thermogenesis present in perfused skeletal muscle but absent from perfused heart', Journal of Thermal Biology, 27, (2) pp. 151-158. ISSN 0306-4565 (2002) [Refereed Article] DOI: 10.1016/S0306-4565(01)00078-X [eCite] [Details] Citations: Scopus - 3Web of Science - 2 Co-authors: Clark MG Tweet
2002	Newman JMB, Rattigan S, Clark MG, 'Nutritive blood flow improves interstitial glucose and lactate exchange in perfused rat hindlimb', American Journal of Physiology - Heart and Circulatory Physiology, 283, (1) pp. H186-H192. ISSN 0363-6135 (2002) [Refereed Article] DOI: 10.1152/ajpheart.01024.2001 [eCite] [Details] Citations: Scopus - 14Web of Science - 16 Co-authors: Newman JMB; Clark MG Tweet
2002	Vincent MA, Dawson D, Clark ADH, Lindner JR, Rattigan S, et al., 'Skeletal Muscle Microvascular Recruitment by Physiological Hyperinsulinemia Precedes Increases in Total Blood Flow', Diabetes, 51, (1) pp. 42-48. ISSN 0012-1797 (2002) [Refereed Article] DOI: 10.2337/diabetes.51.1.42 [eCite] [Details] Citations: Scopus - 168Web of Science - 155 Co-authors: Clark ADH; Clark MG Tweet
2002	Wallis MG, Wheatley C, Rattigan S, Barrett EJ, Clark ADH, et al., 'Insulin-Mediated Hemodynamic Changes Are Impaired in Muscle of Zucker Obese Rats', Diabetes, 51, (12) pp. 3492-3498. ISSN 0012-1797 (2002) [Refereed Article] DOI: 10.2337/diabetes.51.12.3492 [eCite] [Details] Citations: Scopus - 124Web of Science - 112 Co-authors: Wheatley C; Clark ADH; Clark MG Tweet
2001	Clark ADH, Barrett EJ, Rattigan S, Wallis MG, Clark MG, 'Insulin stimulates laser Doppler signal by rat muscle in vivo, consistent with nutritive flow recruitment', Clinical Science, 100, (3) pp. 283-290. ISSN 0143-5221 (2001) [Refereed Article] DOI: 10.1042/CS20000104 [eCite] [Details] Citations: Scopus - 44Web of Science - 45 Co-authors: Clark ADH; Clark MG Tweet
2001	Clark ADH, Youd JM, Rattigan S, Barrett EJ, Clark MG, 'Heterogeneity of laser Doppler flowmetry in perfused muscle indicative of nutritive and non nutritive flow', American Journal of Physiology, 280, (3) pp. H1324-H1333. ISSN 0363-6135 (2001) [Refereed Article] DOI: 10.1152/ajpheart.2001.280.3.H1324 [eCite] [Details] Citations: Web of Science - 23 Co-authors: Clark ADH; Clark MG Tweet
2001	Coggins M, Lindner J, Rattigan S, Jahn L, Fasy E, et al., 'Physiologic Hyperinsulinemia Enhances Human Skeletal Muscle Perfusion by Capillary Recruitment', Diabetes, 50, (12) pp. 2682-2690. ISSN 0012-1797 (2001) [Refereed Article] DOI: 10.2337/diabetes.50.12.2682 [eCite] [Details] Citations: Scopus - 202Web of Science - 193 Tweet
2001	Keske MAV, Rattigan S, Clark MG, 'Size-Dependent Effects of Microspheres on Vasoconstrictor-Mediated Change in Oxygen Uptake by Perfused Rat Hindlimb', Microvascular Research, 62, (3) pp. 306-314. ISSN 0026-2862 (2001) [Refereed Article] DOI: 10.1006/mvre.2001.2344 [eCite] [Details] Citations: Scopus - 2Web of Science - 2 Co-authors: Keske MAV; Clark MG Tweet
2001	Keske MAV, Rattigan S, Clark MG, Bernard SL, Glenny RW, 'Spatial Distribution of Nutritive and Nonnutritive Vascular Routes in Perfused Rat Hindlimb Muscle Using Microspheres', Microvascular Research, 61, (1) pp. 111-121. ISSN 0026-2862 (2001) [Refereed Article] DOI: 10.1006/mvre.2000.2278 [eCite] [Details] Citations: Scopus - 4Web of Science - 3 Co-authors: Keske MAV; Clark MG Tweet
2001	Newman JMB, DiMaria CA, Rattigan S, Clark MG, 'Nutritive blood flow affects microdialysis O/I ratio for [¹⁴C]ethanol and ³H₂O in perfused rat hindlimb', American Journal of Physiology-Heart and Circulatory Physiology, 281, (6) pp. H2731-H2737. ISSN 0363-6135 (2001) [Refereed Article] DOI: 10.1152/ajpheart.2001.281.6.H2731 [eCite] [Details] Citations: Web of Science - 24 Co-authors: Newman JMB; Clark MG Tweet
2001	Rattigan S, Wallis MG, Youd JM, Clark MG, 'Exercise Training Improves Insulin-Mediated Capillary Recruitment in Association With Glucose Uptake in Rat Hindlimb', Diabetes, 50, (12) pp. 2659-2665. ISSN 0012-1797 (2001) [Refereed Article] DOI: 10.2337/diabetes.50.12.2659 [eCite] [Details] Citations: Scopus - 50Web of Science - 52 Co-authors: Clark MG Tweet
2000	Clark MG, Clark ADH, Rattigan S, 'Failure of laser Doppler signal to correlate with total flow in muscle: Is this a question of vessel architecture?', Microvascular Research, 60, (3) pp. 294-301. ISSN 0026-2862 (2000) [Refereed Article] DOI: 10.1006/mvre.2000.2273 [eCite] [Details] Citations: Scopus - 13Web of Science - 11 Co-authors: Clark MG; Clark ADH Tweet
2000	Clark MG, Clerk LH, Newman JMB, Rattigan S, 'Interaction between metabolism and flow in tendon and muscle', Scandinavian Journal of Medicine and Science in Sports, 10, (6) pp. 338-345. ISSN 0905-7188 (2000) [Refereed Article] DOI: 10.1034/j.1600-0838.2000.010006338.x [eCite] [Details] Citations: Scopus - 10Web of Science - 10 Co-authors: Clark MG; Newman JMB Tweet
2000	Clark MG, Rattigan S, Clerk LH, Keske MAV, Clark AD, et al., 'Nutritive and non-nutritive blood flow: rest and exercise', Acta Physiologica Scandinavica, 168, (4) pp. 519-530. ISSN 0001-6772 (2000) [Refereed Article] DOI: 10.1046/j.1365-201X.2000.00704.x [eCite] [Details] Citations: Scopus - 67Web of Science - 64 Co-authors: Clark MG; Keske MAV; Clark AD; Newman JMB Tweet
2000	Clerk LH, Smith ME, Rattigan S, Clark MG, 'Increased chylomicron triglyceride hydrolysis by connective tissue flow in perfused rat hindlimb: Implications for lipid storage', Journal of Lipid research, 41, (3) pp. 329-335. ISSN 0022-2275 (2000) [Refereed Article] PMID: 10706580 [eCite] [Details] Citations: Scopus - 19Web of Science - 16 Co-authors: Smith ME; Clark MG Tweet
2000	Newman JMB, DiMaria CA, Rattigan S, Steen JT, Miller KAL, et al., 'Relationship of MTT reduction to stimulants of muscle metabolism', Chemico-Biological Interactions, 128, (2) pp. 127-140. ISSN 0009-2797 (2000) [Refereed Article] DOI: 10.1016/S0009-2797(00)00192-7 [eCite] [Details] Citations: Scopus - 8Web of Science - 6 Co-authors: Newman JMB; Steen JT; Miller KAL; Eldershaw TPD; Clark MG Tweet
2000	Youd JM, Rattigan S, Clark MG, 'Acute impairment of insulin-mediated capillary recruitment and glucose uptake in rat skeletal muscle in vivo by TNF-alpha', Diabetes, 49, (11) pp. 1904-1909. ISSN 0012-1797 (2000) [Refereed Article] DOI: 10.2337/diabetes.49.11.1904 [eCite] [Details] Citations: Scopus - 153Web of Science - 134 Co-authors: Clark MG Tweet
1999	Rattigan S, Clark MG, Barrett EJ, 'Acute vasoconstriction-induced insulin resistance in rat muscle in vivo', Diabetes, 48, (3) pp. 564-569. ISSN 0012-1797 (1999) [Refereed Article] DOI: 10.2337/diabetes.48.3.564 [eCite] [Details] Citations: Scopus - 101Web of Science - 95 Co-authors: Clark MG Tweet
1999	Tong CYA, DiMaria CA, Rattigan S, Clark MG, 'Na⁺ channel and Na⁺/K⁺ ATPase involvement in norepinephrine- and veratridine-stimulated metabolism in perfused rat hind limb', Canadian Journal of Physiology and Pharmacology, 77, (5) pp. 350-357. ISSN 0008-4212 (1999) [Refereed Article] DOI: 10.1139/cjpp-77-5-350 [eCite] [Details] Citations: Scopus - 11Web of Science - 11 Co-authors: Clark MG Tweet
1999	Youd JM, Newman JMB, Clark MG, Appleby GJ, Rattigan S, et al., 'Increased metabolism of infused 1-methylxanthine by working muscle', Acta Physiologica Scandinavica, 166, (4) pp. 301-308. ISSN 0001-6772 (1999) [Refereed Article] DOI: 10.1046/j.1365-201x.1999.00572.x [eCite] [Details] Citations: Scopus - 14Web of Science - 17 Co-authors: Newman JMB; Clark MG; Appleby GJ; Keske MAV Tweet
1998	Clark MG, Rattigan S, Newman JMB, Eldershaw TPD, 'Vascular control of nutrient delivery by flow distribution within muscle: implications for exercise and post-exercise muscle metabolism', International Journal of Sports Medicine, 19, (6) pp. 391-400. ISSN 0172-4622 (1998) [Refereed Article] DOI: 10.1055/s-2007-971935 [eCite] [Details] Citations: Scopus - 20Web of Science - 21 Co-authors: Clark MG; Newman JMB; Eldershaw TPD Tweet
1998	Keske MAV, Rattigan S, Clark MG, 'Microsphere infusion reverses vasoconstrictor-mediated changes in hindlimb oxygen uptake and energy status', Acta Physiologica Scandinavica, 164, (1) pp. 61-70. ISSN 0001-6772 (1998) [Refereed Article] DOI: 10.1046/j.1365-201X.1998.00408.x [eCite] [Details] Citations: Scopus - 10Web of Science - 10 Co-authors: Keske MAV; Clark MG Tweet
1998	Tong CYA, Rattigan S, Clark MG, 'Similarities between vasoconstrictor- and veratridine-stimulated metabolism in perfused rat hind limb', Canadian Journal of Physiology and Pharmacology, 76, (2) pp. 125-132. ISSN 0008-4212 (1998) [Refereed Article] DOI: 10.1139/y97-179 [eCite] [Details] Citations: Scopus - 5Web of Science - 5 Co-authors: Clark MG Tweet
1997	Rattigan S, Appleby GJ, Miller KAL, Steen JT, Dora KA, et al., 'Serotonin inhibition of 1-methylxanthine metabolism parallels its vasoconstrictor activity and inhibition of oxygen uptake in perfused rat hindlimb', Acta Physiologica Scandinavica, 161, (2) pp. 161-169. ISSN 0001-6772 (1997) [Refereed Article] DOI: 10.1046/j.1365-201X.1997.00215.x [eCite] [Details] Citations: Scopus - 34Web of Science - 37 Co-authors: Appleby GJ; Miller KAL; Steen JT; Dora KA; Colquhoun EQ; Clark MG Tweet
1997	Rattigan S, Clark MG, Barrett EJ, 'Hemodynamic actions of insulin in rat skeletal muscle: evidence of capillary recruitment', Diabetes, 46, (9) pp. 1381-1388. ISSN 0012-1797 (1997) [Refereed Article] DOI: 10.2337/diabetes.46.9.1381 [eCite] [Details] Citations: Scopus - 216Web of Science - 214 Co-authors: Clark MG Tweet
1997	Tong CYA, Rattigan S, Dora KA, Clark MG, 'Vasoconstrictor-mediated increase in muscle resting thermogenesis is inhibited by membrane-stabilizing agents', Canadian Journal of Physiology and Pharmacology, 75, (7) pp. 763-771. ISSN 0008-4212 (1997) [Refereed Article] DOI: 10.1139/cjpp-75-7-763 [eCite] [Details] Citations: Scopus - 11Web of Science - 10 Co-authors: Clark MG Tweet
1996	Newman JMB, Dora KA, Rattigan S, Edwards SJ, Colquhoun EQ, et al., 'Norepinephrine and serotonin vasoconstriction in rat hindlimb control different vascular flow routes', American Journal of Physiology, 270, (4) pp. E689-E699. ISSN 0193-1849 (1996) [Refereed Article] DOI: 10.1152/ajpendo.1996.270.4.E689 [eCite] [Details] Citations: Web of Science - 47 Co-authors: Newman JMB; Dora KA; Edwards SJ; Colquhoun EQ; Clark MG Tweet
1996	Rattigan S, Dora KA, Tong CYA, Clark MG, 'Perfused skeletal muscle contraction and metabolism improved by angiotensin II-mediated vasoconstriction', American Journal of Physiology, 271, (1) pp. E96-E103. ISSN 0193-1849 (1996) [Refereed Article] DOI: 10.1152/ajpendo.1996.271.1.E96 [eCite] [Details] Citations: Web of Science - 39 Co-authors: Dora KA; Clark MG Tweet
1995	Clark MG, Colquhoun EQ, Rattigan S, Dora KA, Eldershaw TPD, et al., 'Vascular and endocrine control of muscle metabolism', American Journal of Physiology: Endocrinology and Metabolism, 268, (5) pp. E797-E812. ISSN 0193-1849 (1995) [Refereed Article] DOI: 10.1152/ajpendo.1995.268.5.E797 [eCite] [Details] Citations: Web of Science - 154 Co-authors: Clark MG; Colquhoun EQ; Dora KA; Eldershaw TPD; Hall JL; Ye JM Tweet
1995	Eldershaw TPD, Rattigan S, Cawthorne MA, Buckingham RE, Colquhoun EQ, et al., 'Treatment with the thiazolidinedione (BRL 49653) decreases insulin resistance in obese Zucker hindlimb', Hormone and Metabolic Research, 27, (4) pp. 169-172. ISSN 0018-5043 (1995) [Refereed Article] DOI: 10.1055/s-2007-979932 [eCite] [Details] Citations: Scopus - 29Web of Science - 30 Co-authors: Eldershaw TPD; Colquhoun EQ; Clark MG Tweet
1995	Rattigan S, Dora KA, Colquhoun EQ, Clark MG, 'Inhibition of insulin-mediated glucose uptake in rat hindlimb by an alpha-adrenergic vascular effect', American Journal of Physiology: Endocrinology and Metabolism, 268, (2) pp. E305-E311. ISSN 0193-1849 (1995) [Refereed Article] DOI: 10.1152/ajpendo.1995.268.2.E305 [eCite] [Details] Citations: Web of Science - 29 Co-authors: Dora KA; Colquhoun EQ; Clark MG Tweet
1995	Ye JM, Edwards SJ, Rose RW, Rattigan S, Clark MG, et al., 'Vasoconstrictors alter oxygen, lactate, and glycerol metabolism in the perfused rat hindlimb of a rat kangaroo', American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 268, (5) pp. R1217-R1223. ISSN 0363-6119 (1995) [Refereed Article] DOI: 10.1152/ajpregu.1995.268.5.R1217 [eCite] [Details] Citations: Web of Science - 20 Co-authors: Ye JM; Edwards SJ; Rose RW; Clark MG; Colquhoun EQ Tweet
1994	Eldershaw TPD, Rattigan S, Dora KA, Colquhoun EQ, Clark MG, et al., 'Potential defect in the vascular control of nonshivering thermogenesis in the obese Zucker rat hind limb', Canadian Journal of Physiology and Pharmacology, 72, (12) pp. 1567-1573. ISSN 0008-4212 (1994) [Refereed Article] DOI: 10.1139/y94-225 [eCite] [Details] Citations: Scopus - 2Web of Science - 2 Co-authors: Eldershaw TPD; Dora KA; Colquhoun EQ; Clark MG Tweet
1989	Rattigan S, Davison AG, Cleland PJ, Clark MG, 'Effect of Phorbol Esters on the Distribution and Total Activity of Protein Kinase C in the Perfused Rat Heart', International Journal of Biochemistry, 21, (12) pp. 1415-1420. ISSN 0020-711X (1989) [Refereed Article] DOI: 10.1016/0020-711X(89)90164-X [eCite] [Details] Citations: Scopus - 6Web of Science - 6 Co-authors: Davison AG; Clark MG Tweet

Chapter in Book

(4 outputs)

Year	Citation	Altmetrics
2013	Premilovac D, Ng HLH, Richards SM, Bradley EA, Dwyer RM, et al., 'Role for the Microvasculature in Glucose Uptake in Skeletal Muscle', Glucose Uptake: Regulation, Signaling Pathways and Health Implications (Endocrinology Research and Clinical Developments), Nova Science Publishers, Johnson CC and Williams DB (ed), New York, pp. 109-139. ISBN 978-1-62618-670-5 (2013) [Research Book Chapter] [eCite] [Details] Co-authors: Premilovac D; Ng HLH; Richards SM; Bradley EA; Dwyer RM; Keske MA Tweet
1998	Clark MG, Rattigan S, Dora KA, Newman JMB, Keske MAV, 'Interaction between blood flow, metabolism and exercise', Biochemistry of Exercise X, Human Kinetics, M Hargreaves & M Thompson (ed), Champaign, pp. 35-46. ISBN 0-88011-758-3 (1998) [Research Book Chapter] [eCite] [Details] Co-authors: Clark MG; Dora KA; Newman JMB; Keske MAV
1997	Clark MG, Rattigan S, Dora KA, Newman JMB, Steen JT, et al., 'Vascular and metabolic regulation of muscle', Physiology, Stress and Malnutrition, Lippincott-Raven, Kinney, JM & Tucker, HN (ed), Philadelphia, pp. 325-346. ISBN 0-397-58763-5 (1997) [Research Book Chapter] [eCite] [Details] Co-authors: Clark MG; Dora KA; Newman JMB; Steen JT; Miller KAL; Keske MAV
1988	Clark MG, Rattigan S, Cleland PJ, Edwards SJ, Davison AG, 'Cardiac Ca²⁺ Channels and Sarcolemma Redox', Plasma Membrane Oxidoreductases in Control of Animal and Plant Growth, Plenum Publishing Corporation, FL Crane, DJ Morre, H Low (ed), New York and London, pp. 359-368. ISBN 0-306-43092-4 (1988) [Research Book Chapter] [eCite] [Details] Co-authors: Clark MG; Edwards SJ; Davison AG

Review

(1 outputs)

Year	Citation	Altmetrics
2012	Au M, Rattigan S, 'Barriers to the management of Diabetes Mellitus - is there a future role for Laser Doppler Flowmetry?', The Australasian Medical Journal, 5, (12) pp. 627-632. ISSN 1836-1935 (2012) [Substantial Review] DOI: 10.4066/AMJ.2012.1526 [eCite] [Details] Citations: Scopus - 4 Tweet

Year

Citation

Altmetrics

2012

Au M, Rattigan S, 'Barriers to the management of Diabetes Mellitus - is there a future role for Laser Doppler Flowmetry?', The Australasian Medical Journal, 5, (12) pp. 627-632. ISSN 1836-1935 (2012) [Substantial Review]

DOI: 10.4066/AMJ.2012.1526 [eCite] [Details]

Citations: Scopus - 4

Conference Publication

(60 outputs)

Year	Citation	Altmetrics
2016	Hu Donghua, Russell RD, Sharman JE, Rattigan S, Jacobson GA, et al., 'Effect of blueberry tea on improving metabolic and vascular function in people with and without type 2 diabetes - A Pilot Study', Australian Diabetes Society and Australian Diabetes Educators Association Annual Scientific Meeting 2016, 24-26 August, 2016, Gold Coast, Australia (2016) [Conference Extract] [eCite] [Details] Co-authors: Russell RD; Sharman JE; Jacobson GA; Al-Aubaidy HAM; Richards SM; Keske MAV
2011	Newman JMB, Dwyer RM, Keske MAV, Richards SM, Rattigan S, 'Flow motion in skeletal muscle is associated with increased nutritive flow and insulin action', Proceedings of the 71st Scientific Sessions of the American Diabetes Association, 24-28 June, San Diego, California, pp. 1740-P. (2011) [Conference Extract] [eCite] [Details] Co-authors: Newman JMB; Dwyer RM; Keske MAV; Richards SM
2011	Rattigan S, Newman JMB, Dwyer RM, Richards S, Keske MAV, 'Flow motion in skeletal muscle microvasculature is associated with increased nutritive flow', Australia and New Zealand Microcirculation Society Conference, 30 Nov - 3 Dec, Western Australia (2011) [Conference Extract] [eCite] [Details] Co-authors: Newman JMB; Dwyer RM; Keske MAV
2006	Bradley EA, Clark MG, Rattigan S, 'Acute AICAR infusion stimulates capillary recruitment in skeletal muscle', Diabetes, vol 55, Supplement 1, 9-13 June, 2006, Washington, pp. A336. ISSN 0012-1797 (2006) [Conference Extract] [eCite] [Details] Co-authors: Bradley EA; Clark MG
2006	Clark MG, Dwyer RM, Newman JMB, Richards SM, Rattigan S, 'A comparison of ultrasound and laser Doppler for Measuring Capillary Recruitment Using Models in vitro', Proceedings, 27-30 September, 2006, Indianapolis, pp. 10. (2006) [Conference Extract] [eCite] [Details] Co-authors: Clark MG; Dwyer RM; Newman JMB; Richards SM
2006	Clark MG, Vollus GC, Roberts MK, Rattigan S, 'Insulin delivery to muscle is sensitive to tissue perfusion', Diabetologia, vol 49, Supplement 1, 14-17 September, 2006, Copenhagen-Malmo, pp. 370-371. ISSN 0012-186X (2006) [Conference Extract] [eCite] [Details] Co-authors: Clark MG; Vollus GC
2006	Dwyer RM, Kolka CM, Rattigan S, Clark MG, 'Endothelin-1 inhibits insulin action in vivo', Diabetologia, vol 49, Supplement 1, 14-17 September, 2006, Copenhagen-Malmo, pp. 373. ISSN 0012-186X (2006) [Conference Extract] [eCite] [Details] Co-authors: Dwyer RM; Clark MG
2006	Dwyer RM, Newman JMB, Richards SM, Rattigan S, Clark MG, 'Laser Doppler flowmetry, but not contrast enhanced ultrasound, influenced by flow when measuring changes in muscle capillary recruitment - a study in vitro', Proceedings of Meeting, 13th September, 2006, Copenhagen, pp. 16. (2006) [Conference Extract] [eCite] [Details] Co-authors: Dwyer RM; Newman JMB; Richards SM; Clark MG
2006	Genders AJ, Rattigan S, Clark MG, Richards SM, 'cGMP degrading phosphodiesterases are expressed differentially in skeletal muscle vasculature', Diabetes, vol 55, Supplement 1, 9-13 June, 2006, Washington, pp. A333. ISSN 0012-1797 (2006) [Conference Extract] [eCite] [Details] Co-authors: Genders AJ; Clark MG; Richards SM
2006	Genders AJ, Rattigan S, Clark MG, Richards SM, 'Differential expression of cGMP degrading phosphodiesterases in skeletal muscle vasculature', Proceedings, 24-28 September, 2006, Brisbane, pp. 130. ISSN 1328-4924 (2006) [Conference Extract] [eCite] [Details] Co-authors: Genders AJ; Clark MG; Richards SM
2006	Newman JMB, Clark MG, Dwyer RM, Richards SM, Rattigan S, 'Use of microdialysis to assess capillary recruitment in muscle - a study in vitro', Proceedings of Meeting, 13th September, 2006, Copenhagen, pp. 17. (2006) [Conference Extract] [eCite] [Details] Co-authors: Newman JMB; Clark MG; Dwyer RM; Richards SM
2005	Carins R, Rattigan S, Clark MG, 'Resiniferatoxin treatment reverses impaired capillary recruitment and insulin resistance in the obese Zucker rat', Diabetes, Vol 54, Supplement 1, June 10-14, 2005, San Diego, pp. A16. ISSN 0012-1797 (2005) [Conference Extract] [eCite] [Details] Co-authors: Clark MG
2005	Clark MG, Wallis MG, Smith ME, Kolka CM, Zhang L, et al., 'Glucosamine induces acute insulin resistance in muscle in vivo assocaited with impaired capillary recruitment', Diabetologia, 48 (S1), 10-15 September, 2005, Athens, pp. A210. ISSN 0012-186X (2005) [Conference Extract] [eCite] [Details] Co-authors: Clark MG; Smith ME; Kolka CM; Zhang L; Richards SM
2005	Kolka CM, Rattigan S, Richards SM, Clark MG, 'Endothelin-1 vascular and resultant metabolic actions in perfused rat hindlimb are opposed by insulin', Diabetologia, vol 48, Supplement 1, 10-15 September, 2005, Athens, pp. A230. ISSN 0012-186X (2005) [Conference Extract] [eCite] [Details] Co-authors: Kolka CM; Richards SM; Clark MG
2005	Mahajan H, Richards SM, Rattigan S, Clark MG, 'Local infusion of an inhibitor of Ca²⁺ dependent K⁺ channels (TEA), but not L-NAME blocks insulin-mediated capillary recruitment and glucose uptake in muscle in vivo', Diabetes, Vol 54, Supplement 1, June 10-14, 2005, San Diego, pp. A379. ISSN 0012-1797 (2005) [Conference Extract] [eCite] [Details] Co-authors: Mahajan H; Richards SM; Clark MG
2005	Vollus GC, Newman JMB, Richards SM, Barrett EJ, Rattigan S, 'Partial microsphere embolism of muscle leads to acute impairment of insulin-mediated glucose uptake without compromising resting energetics', Diabetes, Vol 54, Supplement 1, June 10-14, 2005, San Diego, pp. A379. ISSN 0012-1797 (2005) [Conference Extract] [eCite] [Details] Co-authors: Vollus GC; Newman JMB; Richards SM
2004	Kolka CM, Rattigan S, Richards SM, Clark MG, 'Endothelin-1 as a messenger for insulin has both stimulatory and inhibitory effects on perfused muscle metabolism via its vascular actions', Diabetes, Vol 53, Supplement 2, June 4-8, 2004, Orlando, pp. A368. ISSN 0012-1797 (2004) [Conference Extract] [eCite] [Details] Co-authors: Kolka CM; Richards SM; Clark MG
2004	Mahajan H, Richards SM, Rattigan S, Clark MG, 'Local methacholine but not bradykinin potentiates insulin-mediated capillary recruitment and glucose uptake in muscle in vivo', Diabetes, Vol 53, Supplement 2, June 4-8, 2004, Orlando, pp. A369. ISSN 0012-1797 (2004) [Conference Extract] [eCite] [Details] Co-authors: Mahajan H; Richards SM; Clark MG
2004	Steinberg GR, Dwyer RM, Carey AL, Rogers S, Richards SM, et al., 'Interleukin-6 increases glucose uptake but does not increase AMPK activity in L6 myotubes and perfused rat hindlimb', Proceedings of AMPK Meeting, 23-26 March, 2004, Lorne, pp. 126. (2004) [Conference Extract] [eCite] [Details] Co-authors: Dwyer RM; Richards SM; Clark MG
2004	Wheatley CM, Barrett EJ, Bradley EA, Richards SM, Clark MG, et al., 'Muscle capillary recruitment and glucose uptake of genetically obese rats respond to contractions but not insulin', Diabetes, Vol 53, Supplement 2, June 4-8, 2004, Orlando, pp. A371. ISSN 0012-1797 (2004) [Conference Extract] [eCite] [Details] Co-authors: Bradley EA; Richards SM; Clark MG
2004	Wheatley CM, Richards SM, Clark MG, Barrett EJ, Rattigan S, 'Role of capillary recruitment in the potentiation of insulin action by prior exercise', Diabetes, Vol 53, Supplement 2, June 4-8, 2004, Orlando, pp. A28. ISSN 0012-1797 (2004) [Conference Extract] [eCite] [Details] Co-authors: Richards SM; Clark MG
2003	Bradley EA, Zhang L, Newman JMB, Richards SM, Clark MG, et al., 'Acute divergent effects of AICAR on insulin action in vivo', Diabetes, Vol 52, Supplement 1, June 13-17, 2003, New Orleans, pp. A344. ISSN 0012-1797 (2003) [Conference Extract] [eCite] [Details] Co-authors: Bradley EA; Zhang L; Newman JMB; Richards SM; Clark MG
2003	Clark MG, Zhang L, Wheatley CM, Febbraio MA, Rattigan S, 'TNFα and IL-6 differently affect insulin action in vivo', Diabetologia, Vol 46, Supplement 2, 24-29 August, 2003, Paris, pp. A58. ISSN 0012-186X (2003) [Conference Extract] [eCite] [Details] Co-authors: Clark MG; Zhang L
2003	Mahajan H, Richards SM, Rattigan S, Clark MG, 'T-1032 a cyclic GMP phosphodiesterase-5 inhibitor blocks physiologic insulin-mediated muscle hemodynamic effects and glucose uptake in vivo', Diabetes, Vol 52, Supplement 1, June 13-17, 2003, New Orleans, pp. A541. ISSN 0012-1797 (2003) [Conference Extract] [eCite] [Details] Co-authors: Mahajan H; Richards SM; Clark MG
2003	Rattigan S, Bradley EA, Clark MG, 'Effects of wortmannin on insulin-mediated action in vivo', Diabetes, Vol 52, Supplement 1, June 13-17, 2003, New Orleans, pp. A543. ISSN 0012-1797 (2003) [Conference Extract] [eCite] [Details] Co-authors: Bradley EA; Clark MG
2003	Richards SM, Wheatley CM, Zhang L, Rattigan S, Barrett EJ, et al., 'Contraction-mediated muscle capillary recruitment and metabolic responses in vivo are resistant to TNFα', Diabetologia, Vol 46, Supplement 2, 24-29 August, 2003, Paris, pp. A58. ISSN 0012-186X (2003) [Conference Extract] [eCite] [Details] Co-authors: Richards SM; Zhang L; Clark MG
2003	Zhang L, Richards SM, Rattigan S, Barrett EJ, Clark MG, 'Capillary recruitment in muscle is a highly sensitive event in insulin action in vivo', Diabetes, Vol 52, Supplement 1, June 13-17, 2003, New Orleans, pp. A48. ISSN 0012-1797 (2003) [Conference Extract] [eCite] [Details] Co-authors: Zhang L; Richards SM; Clark MG
2002	Clerk LH, Smith ME, Rattigan S, Clark MG, 'Reduced nutritive flow in experimental hypertension: the cause of hyperglycemia and hyperlipidemia?', Diabetes, Vol 51, Supplement 2, June 14-18, 2002, San Francisco, pp. A335. ISSN 0012-1797 (2002) [Conference Extract] [eCite] [Details] Co-authors: Smith ME; Clark MG
2002	Wheatley CM, Bradley EA, Wallis MG, Rattigan S, Richards SM, et al., 'Contraction-mediated capillary recruitment is not impaired in muscle of insulin-resistant obese Zucker rats', Diabetes, Vol 51, Supplement 2, June 14-18, 2002, San Francisco, pp. A564. ISSN 0012-1797 (2002) [Conference Extract] [eCite] [Details] Co-authors: Bradley EA; Richards SM; Clark MG
2002	Zhang L, Rattigan S, Richards SM, Clark MG, 'TNF? inhibits low physiologic but not high insulin-mediated capillary recruitment and glucose uptake in vivo', Diabetes, Vol 51, Supplement 2, June 14-18, 2002, San Francisco, pp. A565. ISSN 0012-1797 (2002) [Conference Extract] [eCite] [Details] Co-authors: Zhang L; Richards SM; Clark MG
2001	Clark ADH, Wallis MG, Rattigan S, Barrett EJ, Clark MG, 'Insulin-mediated capillary recruitment is impaired in muscle of obese Zucker rats', Diabetes, Vol 50, Supplement 2, June 22-26, 2001, Philadelphia, pp. A329. ISSN 0012-1797 (2001) [Conference Extract] [eCite] [Details] Co-authors: Clark ADH; Clark MG
2001	Clark MG, Barrett EJ, Richards SM, Clark ADH, Rattigan S, 'Microvascular involvement in insulin resistance of skeletal muscle', Proceedings of the 7th World Congress for Microcirculation, August 19-22, 2001, Sydney, pp. 31-37. (2001) [Non Refereed Conference Paper] [eCite] [Details] Co-authors: Clark MG; Richards SM; Clark ADH
2001	Clark MG, Rattigan S, 'Microvascular involvement in insulin resistance of skeletal muscle', Proceedings of the 7th World Congress for Microcirculation, 19-22 August, 2001, Sydney, pp. 3. (2001) [Conference Extract] [eCite] [Details] Co-authors: Clark MG
2001	Clark MG, Rattigan S, 'Insulin-mediated capillary recruitment in muscle: implications for glucose uptake and insulin resistance', Proceedings of the Australian Physiological and Pharmacolical Society, 2-3 September, 2001, Melbourne, pp. 9P. ISSN 0067-2084 (2001) [Conference Extract] [eCite] [Details] Co-authors: Clark MG
2001	Keske MAV, Rattigan S, Clark MG, Barrett EJ, 'Inhibition of nitric oxide synthase prevents insulin-stimulated capillary recruitment and glucose uptake in skeletal muscle in vivo', Diabetes, vol 50, Supplement 2, June 22-26, 2001, Philadelphia, pp. A334. ISSN 0012-1797 (2001) [Conference Extract] [eCite] [Details] Co-authors: Keske MAV; Clark MG
2001	Newman JMB, DiMaria CA, Rattigan S, Clark MG, 'Nutritive and non-nutritive blood flow in muscle affects microdialysis outflow/inflow ratio', Proceedings of the 7th World Congress for Microcirculation, 19-22 August, 2001, Sydney, pp. Pos 2-30. (2001) [Conference Extract] [eCite] [Details] Co-authors: Newman JMB; Clark MG
2001	Rattigan S, 'Insulin Action in Skeletal Muscle and Skin Microcirculation', Proceedings of the 7th World Congress for Microcirculation, 19-22 August, 2001, Sydney, pp. Sym 16. (2001) [Chair International Conference] [eCite] [Details]
2001	Rattigan S, Wallis MG, Youd JM, Clark MG, 'Insulin-mediated capillary recruitment and glucose uptake in rat hindlimb enhanced by voluntary exercise training', Diabetes, Vol 50, Supplement 2, June 22-26, 2001, Philadelphia, pp. A225. ISSN 0012-1797 (2001) [Conference Extract] [eCite] [Details] Co-authors: Clark MG
2001	Rattigan S, Wallis MG, Youd JM, Clark MG, 'Exercise training by rats enhances insulin's microvascular effects in skeletal muscle', Proceedings of the 7th World Congress for Microcirculation, 19-22 August, 2001, Sydney, pp. Pos 1-49. (2001) [Conference Extract] [eCite] [Details] Co-authors: Clark MG
2000	Clark MG, Youd JM, Newman JMB, Rattigan S, 'Sciatic nerve severance produces insulin resistance without changes in 1-MX metabolism', Diabetes, vol 49, Supplement 1, 9-13 June, 2000, San Antonio, TX, USA, pp. 1736-PO. ISSN 0012-1797 (2000) [Conference Extract] [eCite] [Details] Co-authors: Clark MG; Newman JMB
2000	Clerk LH, Smith ME, Rattigan S, Clark MG, 'Haemodynamic insulin resistance increases fatty acid uptake by connective tissue adipocytes in red muscles', Diabetologia, vol 43, Supplement 1, 17-21 September, 2000, Jerusalem, Israel, pp. A163. ISSN 0012-186X (2000) [Conference Extract] [eCite] [Details] Co-authors: Smith ME; Clark MG
1999	DiMaria CA, Tong CYA, Rattigan S, Clark MG, 'Thermogenesis in resting muscle: a role for sodium channels?', Proceedings of the Australian Society for Biochemistry and Molecular Biology, 27-30 September 1999, Gold Coast, pp. 2. ISSN 1328-4924 (1999) [Conference Extract] [eCite] [Details] Co-authors: Clark MG
1999	Rattigan S, Clark MG, 'Oxygen uptake stimulated by veratridine but not phenylephrine in the constant-flow arrested rat heart: absence of vasoconstrictor-mediated thermogenesis in heart', Proceedings of the Australian Society for Biochemistry and Molecular Biology, 27-30 September 1999, Gold Coast, pp. 38. ISSN 1328-4924 (1999) [Conference Extract] [eCite] [Details] Co-authors: Clark MG
1998	Clerk LH, Smith ME, Rattigan S, Clark MG, 'Circulating triglyceride and muscle', Proceedings of the Australasian Society for the Study of Obesity, 24-25 October, 1998, Gold Coast, Qld, pp. 26. (1998) [Conference Extract] [eCite] [Details] Co-authors: Smith ME; Clark MG
1998	DiMaria CA, Tong CYA, Rattigan S, Clark MG, 'Thermogenesis of resting muscle: key roles for sodium channels and Na+/K+ ATPase in catecholamine effects', Proceedings of the Australian Society for Biochemistry and Molecular Biology, 28 September - 1 October, 1998, Adelaide, pp. 193. ISSN 1328-4924 (1998) [Conference Extract] [eCite] [Details] Co-authors: Clark MG
1998	Rattigan S, Barrett EJ, Clark MG, 'Vascular induced insulin resistance', Proceedings of the Australian Diabetes Society and Australian Diabetes Educators Association, 26-28 August, 1998, Perth, pp. 127. ISBN 1-875690-23-9 (1998) [Conference Extract] [eCite] [Details] Co-authors: Clark MG
1998	Rattigan S, Youd JM, Clark MG, 'Insulin action and blood flow within muscle', Proceedings of the Australian Society for Medical Research, 22-25 November 1998, Hobart, pp. S7.4. (1998) [Conference Extract] [eCite] [Details] Co-authors: Clark MG
1998	Youd JM, Rattigan S, Clark ADH, Clark MG, 'Blood flow and glucose uptake by muscle', Proceedings of the Australian Society for Biochemistry and Molecular Biology, 28 September - 1 October, Adelaide, pp. 6. ISSN 1328-4924 (1998) [Conference Extract] [eCite] [Details] Co-authors: Clark ADH; Clark MG
1997	Clark MG, Rattigan S, Barrett EJ, 'Regulation of muscle glucose uptake in vivo by insulin-mediated capillary recruitment', Proceedings of the Australian Society for Biochemistry and Molecular Biology, Melbourne, pp. Sym B5-2. (1997) [Conference Extract] [eCite] [Details] Co-authors: Clark MG
1997	Newman JMB, Clark MG, Rattigan S, Appleby GJ, Keske MAV, et al., 'Effect of Muscle Contraction on Metabolism of 1-Methylxanthine and L-Arginine in the Constant-Flow Perfused Rat Hindlimb', 10th International Conference on the Biochemistry of Exercise, Sydney, pp. 76. (1997) [Conference Extract] [eCite] [Details] Co-authors: Newman JMB; Clark MG; Appleby GJ; Keske MAV
1997	Rattigan S, Barrett EJ, Appleby GJ, Clark MG, '1-Methylxanthine Metabolism in Rat Skeletal Muscle Indicative of Nutritive Blood flow in Vitro and in Vivo', 10th International Biochemistry of Exercise Conference, Sydney, pp. 76. (1997) [Conference Extract] [eCite] [Details] Co-authors: Appleby GJ; Clark MG
1997	Rattigan S, Barrett EJ, Clark MG, 'Evidence of Capillary Recruitment by Insulin but not Epinephrine in Rat Muscle in Vivo', Diabetes, New Orleans, USA, pp. 84A. (1997) [Conference Extract] [eCite] [Details] Co-authors: Clark MG
1997	Rattigan S, Barrett EJ, Clark MG, 'Hemodynamic Effects of Insulin Action in Rat Skeletal Muscle in Vivo', FASEB Journal, Los Angeles, pp. A506. (1997) [Conference Extract] [eCite] [Details] Co-authors: Clark MG
1997	Youd JM, Rattigan S, Keske MAV, Clark MG, 'Sciatic Nerve Severance Produces Haemodynamic Changes and Insulin Resistance in Muscle', Diabetologia, Helsinki, pp. A257. (1997) [Conference Extract] [eCite] [Details] Co-authors: Keske MAV; Clark MG
1996	Clark MG, Rattigan S, Barrett EJ, 'Vasoconstrictor-mediated blood flow redistribution and acute insulin resistance in rat skeletal muscle in vivo', European Association for the Study of Diabetes, Vienna, Austria, pp. A175. (1996) [Conference Extract] [eCite] [Details] Co-authors: Clark MG
1996	Rattigan S, Barrett EJ, Clark MG, 'Insulin alters the distribution of volume of blood flow in rat skeletal muscle in vivo: Assessment by 1-methylxanthine metabolism and ultrasound', American Diabetes Association Meeting, San Francisco, CA USA, pp. 307A. (1996) [Conference Extract] [eCite] [Details] Co-authors: Clark MG
1996	Rattigan S, Barrett EJ, Clark MG, 'Skeletal muscle vascular involvement in insulin action and insulin resistance', International Symposium on Resistance Arteries 1996, Cambridge, UK, pp. 25. (1996) [Conference Extract] [eCite] [Details] Co-authors: Clark MG
1995	Eldershaw TPD, Colquhoun EQ, Dora KA, Rattigan S, Clark MG, 'Increased resting muscle thermogenesis using pharmacological intervention', Fourth Scientific Meeting of the Australian Society for the Study of Obesity, Melbourne, Vic., pp. 41. (1995) [Conference Extract] [eCite] [Details] Co-authors: Eldershaw TPD; Colquhoun EQ; Dora KA; Clark MG
1995	Matthias A, Miller KAL, Newman JMB, Steen JT, Rattigan S, et al., 'Fatty acids as potential mediators of skeletal muscle thermogenesis', 1st Colloquium on Mitochondria and Myopathies, Halle/Saale, pp. B60. (1995) [Conference Extract] [eCite] [Details] Co-authors: Miller KAL; Newman JMB; Steen JT; Dora KA; Colquhoun EQ; Clark MG
1995	Ye JM, Dora KA, Rattigan S, Clark MG, Colquhoun EQ, 'Stimulation of oxygen uptake (VO2) in muscle by alpha1- and beta3-adrenoceptors', Fourth Scientific Meeting of the Australian Society for the Study of Obesity, Melbourne, Vic., pp. 40. (1995) [Conference Extract] [eCite] [Details] Co-authors: Ye JM; Dora KA; Clark MG; Colquhoun EQ

Patent

(4 outputs)

Year	Citation	Altmetrics
2001	Clark MG, Rattigan S, 'Methods and pharmaceuticals for treating muscle insulin resistance and related conditions' (2001) [Patent Application] [eCite] [Details] Co-authors: Clark MG
2001	Clark MG, Rattigan S, 'Methods and pharmaceuticals for treating muscle insulin resistance and related conditions' (2001) [Patent] [eCite] [Details] Co-authors: Clark MG
2001	Clark MG, Rattigan S, Barret EJ, Lindner J, Kaul S, 'Improved method of measuring changes in microvascular capillary blood flow' (2001) [Patent] [eCite] [Details] Co-authors: Clark MG
2001	Clark MG, Rattigan S, Barrett EJ, Lindner JR, Kaul S, 'Improved method of measuring changes in microvascular capillary blood flow' (2001) [Patent Application] [eCite] [Details] Co-authors: Clark MG

Grants & Funding

In the last 5 years Prof Rattigan has obtained competitive research funding from ARC, NHMRC, National Institutes of Health USA, Diabetes Australia, National Heart Foundation and other granting bodies totalling over $2.2 million.

Funding Summary

Number of grants

Total funding

$8,866,219

Projects

Mixed Meal Challenge A new diagnostic test for screening pre diabetes (2016)$24,225

Description: The oral glucose tolerance test (GTT) is the gold standard for assessing pre-diabetes and type 2 diabetes (T2D), and is used world-wide. However, our researchgroup has made an important discovery demonstrating the GTT causes acute microvascular insulin resistance in healthy people. These findings have asignificant clinical impact as it implies that the GTT does not have the sensitivity to identify people with vascular-derived insulin resistance which is one of theearliest events in the development of pre-diabetes. Therefore, people with vascular‐derived insulin resistance are not being identified or diagnosed. We have developed an alternative test (the mixed meal challenge; MMC) and hypothesise it will have greater capacity to screen for pre-diabetes.Aim 1: Determine whether the MMC can identify pre-diabetes in a population of people that would otherwise be considered healthy in response to a GTT.Aim 2: Determine whether the benefits of the MMC as a new diagnostic test is linked to microvascular insulin sensitivity in skeletal muscle.
Funding: Royal Hobart Hospital Research Foundation ($24,225)
Scheme: Grant-Establishment
Administered By: University of Tasmania
Research Team: Keske MAV; Greenaway TM; Rattigan S; Russell RD; Neilson S
Year: 2016

Microvascular dysfunction in adult offspring of type 2 diabetics (2014)$20,294

Description: Offspring from type 2 diabetics (T2D) are at much greater risk of developing diabetes than a person with no family history. The mechanism for this increase in risk is not known. This project will determine whether microvascular dysfunction in skeletal muscle and skin of first degree relatives with T2D occurs before development of insulin resistance. We will recruit people with and without family history of T2D. It will measure microvascular actions (using ultrasound) in these people before and after a mixed meal challenge. The outcomes of this study will determine whether monitoring microvasculature responses in muscle is an important 'early' strategy for assessing risk that might inform patient treatment to prevent or delay progression to insulin resistance or T2D.
Funding: Royal Hobart Hospital Research Foundation ($20,294)
Scheme: Grant-Clinical Research
Administered By: University of Tasmania
Research Team: Keske MAV; Rattigan S; Sharman JE; Russell R; Premilovac D
Year: 2014

Cardiometabolic benefits of exercise training in type 2 diabetes independent of weight loss (2014)$50,735

Description: This project will recruit an overweight type 2 diabetes cohort, medically assessed for an exercise program. It aims to recruit some with family history of type 2 diabetes and some without. The cohort with exercise test before and after 6 weeks of the exercise program, with type 2 medications discontinued before test. The aim is to show that heart health will not be as good with family history of type 2 and that exercise will improve heart health but will be of more benefit to those with a family history than those without.
Funding: University of Tasmania ($50,735)
Scheme: null
Administered By: University of Tasmania
Research Team: Keske MAV; Greenaway T; Marwick TH; Ross RM; Rattigan S; Sharman JE; Premilovac D
Year: 2014

Role of microvascular flowmotion in skeletal muscle glucose metabolism (2013 - 2015)$576,533

Description: Obesity and type 2 diabetes are nationally and globally reaching epidemic rates. This project investigates the regulation of blood flow within muscle and its impact on metabolism. Outcomes from the study may lead to diagnostic tools and treatments for cardiovascular disease associated with obesity, hypertension and type 2 diabetes.
Funding: National Health & Medical Research Council ($576,533)
Scheme: Grant-Project
Administered By: University of Tasmania
Research Team: Rattigan S; Keske MAV; Richards SM; Ross RM
Period: 2013 - 2015
Grant Reference: 1043474_HF

Neural regulation of skeletal muscle insulin sensitivity (2012)$9,825

Funding: The Select Foundation ($9,825)
Scheme: Grant-Small Grants Scheme
Administered By: University of Tasmania
Research Team: Rattigan S; Keske MAV; Dickson TC
Year: 2012

Actions of the polyphenol epigallocatechin 3-gallate on insulin sensitivity (2011 - 2013)$395,518

Funding: National Health & Medical Research Council ($395,518)
Scheme: Grant-Project
Administered By: University of Tasmania
Research Team: Keske MAV; Rattigan S; Quon M
Period: 2011 - 2013
Grant Reference: 1009962

Microvascular Defects and Insulin Resistance (2011 - 2012)$127,490

Funding: Heart Foundation ($127,490)
Scheme: Grant-In-Aid
Administered By: University of Tasmania
Research Team: Rattigan S; Keske MAV; Richards SM
Period: 2011 - 2012

Near Miss - Microvascular Blood Flow in Cardiovascular Disease (2011)$12,500

Funding: University of Tasmania ($12,500)
Scheme: Grant-Near Misses
Administered By: University of Tasmania
Research Team: Rattigan S
Year: 2011

Does exercise increase skeletal muscle insulin sensitivity via nitric oxide? (2011 - 2013)$543,390

Funding: National Health & Medical Research Council ($543,390)
Scheme: Grant-Project
Administered By: Victoria University
Research Team: McConnell G; Rattigan S
Period: 2011 - 2013
Grant Reference: 1012181

Ambulatory central blood pressure as a novel explanation for diabetes-associated brain damage (2011)$55,597

Funding: Diabetes Australia Research Trust ($55,597)
Scheme: Grant-Research [1 year]
Administered By: University of Tasmania
Research Team: Sharman JE; Rattigan S; Srikanth V
Year: 2011

Steve Rattigan_Discretionary Account (2008 - 2009)$20,000

Funding: Menzies Institute for Medical Research ($20,000)
Scheme: Consultancy
Administered By: University of Tasmania
Research Team: Rattigan S
Period: 2008 - 2009

NHMRC Standard Equipment Grant - 2008 (2008)$72,611

Funding: National Health & Medical Research Council ($72,611)
Scheme: Grant-Equipment
Administered By: University of Tasmania
Research Team: Keske MAV; Rattigan S; Richards SM
Year: 2008
Grant Reference: 580023

Blood Flow Routes in Muscle (2008 - 2010)$390,000

Funding: Australian Research Council ($390,000)
Scheme: Grant-Discovery Projects
Administered By: University of Tasmania
Research Team: Keske MAV; Rattigan S
Period: 2008 - 2010
Grant Reference: DP0877385

NHMRC Research Fellowship (SRFA) (2008 - 2013)$655,657

Funding: National Health & Medical Research Council ($655,657)
Scheme: Fellowship-Research
Administered By: University of Tasmania
Research Team: Rattigan S
Period: 2008 - 2013
Grant Reference: 490034

Interaction between adiponectin and insulin in vascular control of glucose uptake in muscle (2008 - 2009)$119,574

Funding: Heart Foundation ($119,574)
Scheme: Grant-In-Aid
Administered By: University of Tasmania
Research Team: Rattigan S; Richards SM
Period: 2008 - 2009

Central and Peripheral Actions of Insulin for the Control of Muscle Capillary Recruitment (2007 - 2009)$417,750

Funding: National Health & Medical Research Council ($417,750)
Scheme: Grant-Project
Administered By: University of Tasmania
Research Team: Clark MG; Rattigan S; Richards SM; Choi-Lundberg DL
Period: 2007 - 2009
Grant Reference: 457603

Endothelin-1, type2 diabetes and hypertension (2007 - 2008)$112,680

Funding: Heart Foundation ($112,680)
Scheme: Grant-In-Aid
Administered By: University of Tasmania
Research Team: Clark MG; Rattigan S; Richards SM; Kolka CM
Period: 2007 - 2008

The Effects of Insulin on the Microvasculature (2006 - 2010)$347,499

Funding: National Institutes of Health ($347,499)
Scheme: Grant
Administered By: University of Virginia
Research Team: Clark MG; Rattigan S; Richards SM
Period: 2006 - 2010

Isoelectric Focussing System (2006)$15,080

Funding: National Health & Medical Research Council ($15,080)
Scheme: Grant-Equipment
Administered By: University of Tasmania
Research Team: Richards SM; Rattigan S
Year: 2006
Grant Reference: 361670

Nutrient and Hormone Delivery to Muscle: Interactions between Insulin and Exercise (2005 - 2007)$299,500

Funding: National Health & Medical Research Council ($299,500)
Scheme: Grant-Project Three Year
Administered By: University of Tasmania
Research Team: Clark MG; Rattigan S; Richards SM
Period: 2005 - 2007
Grant Reference: 352600

Novel Therapeutic Interventions to Increase Blood Flow to Skeletal Muscle (2005 - 2007)$354,750

Funding: National Health & Medical Research Council ($354,750)
Scheme: Grant-Project
Administered By: National Health & Medical Research Council
Research Team: Febbraio M; Clark MG; Hill M; Hiscock N; Rattigan S
Period: 2005 - 2007
Grant Reference: 342115

Leica DMIRB Inverted Microscope Configured for Fluorescence and Bright Field with Phase Contrast (2005)$10,000

Funding: National Health & Medical Research Council ($10,000)
Scheme: Grant-Equipment
Administered By: University of Tasmania
Research Team: Chuah MI; West AK; Holloway AF; Rattigan S; Richards SM; Chung RS; Foa LC
Year: 2005
Grant Reference: 264668

NIDDM-GSK-Comparing Rosiglitazone and Metformnum for Microvascular Action in Muscle (2004 - 2005)$106,400

Funding: GlaxoSmithKline Australia ($106,400)
Scheme: Contract Research
Administered By: University of Tasmania
Research Team: Clark MG; Rattigan S
Period: 2004 - 2005

Muscle Vascular Research and Gene Therapy Using Ultrasound (2004)$142,900

Funding: Australian Research Council ($102,900)
Collaborators: Deakin University ($10,000); Royal Melbourne Institute of Technology University ($10,000); University of Melbourne ($10,000); University of New South Wales ($10,000)
Scheme: Grant-Linkage Infrastructure
Administered By: University of Tasmania
Research Team: Clark MG; Rattigan S; Richards SM
Year: 2004
Grant Reference: LE0452281

Refrigerated Benchtop Centrifuge (2004)$12,941

Funding: National Health & Medical Research Council ($12,941)
Scheme: Grant-Equipment
Administered By: University of Tasmania
Research Team: Holloway AF; West AK; Chuah MI; Rattigan S; Richards SM
Year: 2004
Grant Reference: 264536

The Role of the Endothelium in Insulin's In Vivo Action Upon Skeletal Muscle Metabolism (2004 - 2006)$444,750

Funding: National Health & Medical Research Council ($444,750)
Scheme: Grant-Project Three Year
Administered By: University of Tasmania
Research Team: Rattigan S
Period: 2004 - 2006
Grant Reference: 302200

Heart Foundation Career Development Fellowship (2004 - 2008)$433,000

Funding: Heart Foundation ($433,000)
Scheme: Fellowship-Postdoctoral
Administered By: University of Tasmania
Research Team: Rattigan S
Period: 2004 - 2008

Gradient Thermal Cycler for PCR (2004)$7,055

Funding: National Health & Medical Research Council ($7,055)
Scheme: Grant-Equipment
Administered By: University of Tasmania
Research Team: Richards SM; Rattigan S
Year: 2004
Grant Reference: 264536

Augmenting Microvascular Blood Flow in Muscle (2003 - 2005)$210,000

Funding: National Health & Medical Research Council ($210,000)
Scheme: Grant-Project Three Year
Administered By: University of Tasmania
Research Team: Clark MG; Richards SM; Rattigan S
Period: 2003 - 2005
Grant Reference: 253900

Relationship Between Muscle Insulin Resistance and High Blood Pressure (2003 - 2004)$90,000

Funding: Heart Foundation ($90,000)
Scheme: Grant-In-Aid
Administered By: University of Tasmania
Research Team: Clark MG; Rattigan S; Richards SM
Period: 2003 - 2004

Mechanisms Linking Insulin-Mediated Muscle Capillary Recruitment and Glucose Uptake (2002 - 2004)$315,000

Funding: National Health & Medical Research Council ($315,000)
Scheme: Grant-Project Three Year
Administered By: University of Tasmania
Research Team: Clark MG; Rattigan S
Period: 2002 - 2004
Grant Reference: 211302

The Physiological Effect of Insulin on Microvascular Flow (2001 - 2005)$686,437

Funding: National Institutes of Health ($686,437)
Scheme: Grant
Administered By: University of Virginia
Research Team: Clark MG; Rattigan S; Clark ADH
Period: 2001 - 2005

Detrimental Haemodynamic Changes in Skeletal Muscle From Chronic Heart Failure (2001 - 2002)$68,400

Funding: Heart Foundation ($68,400)
Scheme: Grant-In-Aid
Administered By: University of Tasmania
Research Team: Clark MG; Rattigan S; Richards SM
Period: 2001 - 2002

Development of Laser Doppler Flowmetry for Assessment of Muscle Microvascular Flow in Insulin Resistance (2000)$32,200

Funding: Clifford Craig Foundation ($32,200)
Scheme: Grant
Administered By: University of Tasmania
Research Team: Clark MG; Rattigan S; Richards SM; Clark ADH
Year: 2000

The Role of Nutritive and Non-nutritive Blood Flow on Lipid Clearance by Normal and Insulin-resistant Muscle (1999 - 2000)$73,514

Funding: Heart Foundation ($73,514)
Scheme: Grant-In-Aid
Administered By: University of Tasmania
Research Team: Clark MG; Rattigan S; Richards SM
Period: 1999 - 2000

Haemodynamic Effects of Tumour Necrosis Factor-A to cause Muscle Insulin Resistance (1999)$20,000

Funding: Diabetes Australia Research Trust ($20,000)
Scheme: Grant-Research [1 year]
Administered By: University of Tasmania
Research Team: Clark MG; Rattigan S; Clark ADH
Year: 1999

Skeletal Muscle Capillary Recruitment and Insulin Action (1999 - 2001)$56,591

Funding: American Diabetes Association ($56,591)
Scheme: Grant
Administered By: University of Tasmania
Research Team: Clark MG; Rattigan S; Clark ADH
Period: 1999 - 2001

Insulin resistance in muscle from haemodynamic changes (1998 - 2002)$574,676

Funding: National Health & Medical Research Council ($574,676)
Scheme: Grant-MRC:Project-Extended
Administered By: University of Tasmania
Research Team: Clark MG; Rattigan S
Period: 1998 - 2002
Grant Reference: 981520

A muscle haemodynamic basis for hypertriglyceridemia and insulin resistance of hypertension. (1997 - 1998)$86,000

Funding: Heart Foundation ($86,000)
Scheme: Grant-Biomedical
Administered By: University of Tasmania
Research Team: Clark MG; Rattigan S
Period: 1997 - 1998

Effects of vasomodulators on lipid clearance by perfused muscle (1996 - 1998)$183,593

Funding: National Health & Medical Research Council ($183,593)
Scheme: Grant-MRC Project
Administered By: University of Tasmania
Research Team: Clark MG; Rattigan S
Period: 1996 - 1998
Grant Reference: 961020

A haemodynamic basis for insulin resistance in skeletal muscle (1995 - 1997)$224,961

Funding: National Health & Medical Research Council ($224,961)
Scheme: Grant-MRC Project
Administered By: University of Tasmania
Research Team: Clark MG; Rattigan S
Period: 1995 - 1997
Grant Reference: 951225

Insulin resistant diabetes resulting from haemodynamic changes within muscle (1995)$100,000

Funding: Australian Mutual Provident Society ($100,000)
Scheme: Grant
Administered By: University of Tasmania
Research Team: Clark MG; Rattigan S
Year: 1995

Diode array detector (1994)$10,400

Funding: National Health & Medical Research Council ($10,400)
Scheme: Grant-Equipment
Administered By: University of Tasmania
Research Team: Clark MG; Colquhoun EQ; Rattigan S
Year: 1994
Grant Reference: 941406

Insulin resistance and obesity from vascular shunting in muscle (1992 - 1994)$266,078

Funding: National Health & Medical Research Council ($266,078)
Scheme: Grant-MRC Project
Administered By: University of Tasmania
Research Team: Clark MG; Colquhoun EQ; Rattigan S
Period: 1992 - 1994
Grant Reference: 921081

Development of pharmacological and dietary factors for the control of obesity (1990 - 1991)$75,115

Funding: National Health & Medical Research Council ($75,115)
Scheme: Grant-MRC Project
Administered By: University of Tasmania
Research Team: Clark MG; Colquhoun EQ; Montgomery IM; Rattigan S
Period: 1990 - 1991
Grant Reference: 900489

Glucose transport in normal and diabetic vascular smooth muscle (1990)$15,000

Funding: Diabetes Australia Research Trust ($15,000)
Scheme: Grant-Research [1 year]
Administered By: University of Tasmania
Research Team: Clark MG; Colquhoun EQ; Rattigan S
Year: 1990

Research Supervision

Professor Rattigan as supervised over 25 successful PhD students, and is currently supervising 3 PhD candidates.

Completed

Degree	Title	Completed
PhD	Role of Adipose Tissue Microvascular Blood Flow in Type 2 Diabetes Candidate: Donghua Hu	2018
PhD	Inflammation is Not a Contributing Factor in the Development of Insulin Resistance in Diet Induced Obesity in Rats Candidate: Aascha Adriana Brown	2017
PhD	Characterisation of Flowmotion in Healthy Controls and Type 2 Diabetes Candidate: Sarah Joan Blackwood	2017
PhD	Effect of the Green Tea Polyphenol, EGCG, on Insulin Sensitivity Candidate: Huei Leng Helena Ng	2014
PhD	Exercise Haemodynamics: Physiology and Clinical Consequences Candidate: Martin Gregory Schultz	2013
PhD	Microvascular Dysfunction and the Development of Muscle Insulin Resistance Candidate: Dino Premilovac	2012
PhD	Hemodynamic and Metabolic Actions of Adiponectin in Muscle Candidate: Carol Therese Bussey	2011
PhD	Role of the Microvasculature in the Development of Muscle Insulin Resistance Candidate: Philippe St-Pierre	2010
Masters	Vascular and Metabolic Actions of Insulin and AMPK Activation in Muscle Candidate: Eloise Alice Bradley	2009
PhD	Enhancing Blood Flow and Glucose Uptake in Insulin-Resistant Skeletal Muscle Candidate: Amanda Joan Genders	2009
PhD	Exercise and Insulin: Muscle Haemodynamics and Metabolism Candidate: Renee Ross	2007
PhD	Glucose Uptake in Skeletal Muscle Candidate: Cathryn Mary Kolka	2006
PhD	Insulin-Mediated Capillary Recruitment: Regulatory and Anatomical Aspects Candidate: Lei Zhang	2005
PhD	Hemodynamic and metabolic changes in muscle in relation to insulin action Candidate: Hema Mahajan	2005
PhD	Novel Technologies and Measurement of Microvascular Blood Flow in Muscle Candidate: Andrew Douglas Hastings Clark	2005
PhD	Interactions between contraction, insulin and thiazolidinediones in skeletal muscle; a focus on capillary recruitment Candidate: Catherine Mary Wheatley	2004
PhD	Relationship of microvascular flow distibution to skeletal muscle metabolism Candidate: John Malcolm Newman	2002
PhD	Regulation of skeletal muscle metabolism Candidate: Carla Francesconi	2002
PhD	Vascular & metabolic actions of insulin Candidate: Michelle Gaye Wallis	2002
PhD	Muscle fuel uptake: a result of hormone and substrate interaction affecting regional blood flow Candidate: Lucy Henrietta Clerk	2002
PhD	Vascular effects of vasoconstrictors on muscle metabolism Candidate: Michelle Anne Vincent	2000
PhD	Nutritive and Non-Nutritive Blood Flow in Muscle Candidate: Joanne Maree Youd	2000
PhD	Vascular control and hindlimb metabolism Candidate: Chung Ying Alex Tong	1998
PhD	Title: The release of purine and pyrimidine nucleotide catabolites from working blood vessels Candidate: Stephen Michael Richards	1993