The Behavioural Neuroscience Group

Our aim is to unravel the complex neural and molecular mechanisms that mediate normal and abnormal behaviour, and determine how these mechanisms overlap with the brain functions that sustain fundamental processes such as emotion, motivation, attention and memory.

We tackle some of the big challenges modern society faces, including addiction, stress and anxiety, and obesity. To provide novel explanations and solutions for these challenges we use a variety of model systems and a myriad of methodological and treatment approaches, ranging from pharmacology, neurochemistry and neuroanatomy to optogenetics, nutritional interventions and fine-grained behavioural analysis and modification. We welcome applications from PhD students seeking to join a thriving multidisciplinary group and pursue a research career.

Expertise

  • Animal models of disease
  • Behavioural pharmacology
  • Molecular pharmacology
  • Neurohistology/imaging
  • Neurochemistry
  • Electrophysiology
  • Cell culture
  • Neurosurgery
  • Immunology

Projects

Investigation of the trace amine-associated receptor 1 (TAAR1) as a target for pharmacotherapy in addictive disorders

This project investigates the therapeutic potential of TAAR1 agonists in animal models of addiction

Modelling addictive behaviour in invertebrates

This project investigates the neurobiology and pharmacology on addictive-like behaviour in flatworms

Mapping of fear memories in the amygdala

This project uses molecular imaging and electrophysiology to unravel the encoding of fear memories in the amygdala complex

Role of MEK inhibitors in the treatment of post-traumatic stress disorder

This project explores the use of MEK inhibitors to interfere with memory consolidation processes in the amygdala associated with maladaptive fear memories

Role of intestinal microbiome and exercise in obesity and brain function

This project studies the relationship between the integrity of enteric microbiome, motivation to exercise and brain plasticity

Influence of gut microbiota on mood and cognition

This project investigates the effect of probiotics on anxiety-like behaviour, depressive symptomatology and memory function

Novel behavioural and pharmacological interventions to halt the development of type 2 diabetes

This project will examine the extent to which increased 1-deoxySL concentrations compromise the functionality of skeletal muscle, glucose metabolism

Biochemical mechanisms of inflammatory disease

This project focuses on chronic intestinal inflammation and colorectal cancer and aims to provide a better understanding of IBD pathogenesis and treatment

Affiliation

School of Psychological Sciences

Contact

Email: juan.canales@utas.edu.au

Group Leader(s)

Group members