Neuroscience PhD Project

How do multiple sclerosis-associated gene variants drive brain pathophysiology in vivo?

Degree type

PhD

Closing date

1 June 2024

Campus

Hobart

Citizenship requirement

Domestic

About the research project

The Neuroscience PhD Candidate will work within Professor Kaylene Young's Glial Research Team (https://discover.utas.edu.au/Kaylene.Young), and use CRISPR-Cas9 modified mice and unique human stem cell resources to determine how multiple sclerosis-associated gene variants contribute to neuropathology and disease progression in high risk families.  The Neuroscience PhD Candidate will study the impact that rare gene variants have on brain repair and behavior following a multiple sclerosis-like injury.  They will study glial and vascular cell morphology in the brain using immunohistochemistry, confocal microscopy and transcriptomics.  The candidate will work collaboratively with neuroscience, computational genetics, immunology, and clinical neurology collaborators.

Primary Supervisor

Meet Prof Kaylene Young

Funding

Applicants will be considered for a Research Training Program (RTP) scholarship or Tasmania Graduate Research Scholarship (TGRS) which, if successful, provides:

  • a living allowance stipend of $32,192 per annum (2024 rate, indexed annually) for 3.5 years
  • a relocation allowance of up to $2,000
  • a tuition fees offset covering the cost of tuition fees for up to four years (domestic applicants only)

If successful, international applicants will receive a University of Tasmania Fees Offset for up to four years.

As part of the application process you may indicate if you do not wish to be considered for scholarship funding.

Other funding opportunities and fees

For further information regarding other scholarships on offer, and the various fees of undertaking a research degree, please visit our Scholarships and fees on research degrees page.

Eligibility

Applicants should review the Higher Degree by Research minimum entry requirements.

Ensure your eligibility for the scholarship round by referring to our Key Dates.

Additional eligibility criteria specific to this project/scholarship:

  • Applicants must be able to undertake the project on-campus
  • Bachelor of Science with first class honors (or equivalent)

Selection Criteria

The project is competitively assessed and awarded.  Selection is based on academic merit and suitability to the project as determined by the College.

Additional essential selection criteria specific to this project:

  • Experience conducting research within a PC2 laboratory
  • Undergraduate training in neuroscience
  • Ability to clearly and accurately communicate research findings in written and oral formats

Additional desirable selection criteria specific to this project:

  • Experience in cryosectioning and immunohistochemistry
  • Working knowledge of rodent neuroanatomy
  • Knowledge of glial cell biology literature
  • Knowledge of multiple sclerosis pathology literature
  • Experience with rodent models of demyelination

Application process

  1. Select your project, and check that you meet the eligibility and selection criteria, including citizenship;
  2. Contact Prof Kaylene Young to discuss your suitability and the project's requirements; and
  3. In your application:
    • Copy and paste the title of the project from this advertisement into your application. If you don’t correctly do this your application may be rejected.
    • Submit a signed supervisory support form, a CV including contact details of 2 referees and your project research proposal.
  4. Apply prior to 1 June 2024.

Full details of the application process can be found under the 'How to apply' section of the Research Degrees website.

Following the closing date applications will be assessed within the College. Applicants should expect to receive notification of the outcome by email by the advertised outcome date.

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